Cell No. : Cell Name
RCB0135 : L5178Y
update : 2021/01/08
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| Comment | Rapidly growing lymphoma |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| Remarks | |
| Order Form |
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
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Basic information
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Depositor |
Kaneko, Ichiro
|
| Year of deposit |
1987
|
| Animal |
mouse
< Mammals
|
| Tissue |
lymph node
|
| Case history |
lymphoma
|
| Classification |
other
|
| History |
RIKEN.-K.Kaneko
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|
Lifespan |
infinite
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| Morphology |
lymphocyte-like
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deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Suspension cells
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| Medium and additives |
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RPMI1640 + 10% FBS
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| Antibiotics |
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Free
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Passage method |
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dilution
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Culture information
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Passage ratio |
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1 : 10 split
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| SC frequency |
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Subculture : 2 times/week
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| Temperature |
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37
℃
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| CO2 concentration |
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5
%
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| Freeze medium |
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Medium + 10% DMSO
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| Freezing method |
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Slow freezing
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| Mycoplasma |
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(-)
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| SSLP(mouse) |
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OK
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| Isozyme |
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LD, NP
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| Chromosome mode |
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32-79(50) : /36(2),37(5),38(10),39(6),40(3),42(5)/
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| Reference information |
Reference |
13
|
| User's Publication |
13
|
| Reference |
|
2617
Applegate, M L, Moore, M M, Broder, C B, Burrell A, Juhn G, Kasweck, K L, Lin, P F, Wadhams A, Hozier, J C
Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells.
Proc Natl Acad Sci U S A
1990
87:51-5
PubMed ID: 1967496
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2616
Chen, L P, Suzuki Y, Liu, C M, Wheelock, E F
Maintenance and cure of the L5178Y murine tumor-dormant state by interleukin 2: dependence of interleukin 2 on induced interferon-gamma and on tumor necrosis factor for its antitumor effects.
Cancer Res
1990
50:1368-74
PubMed ID: 2105837
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2619
Doerr, C L, Harrington-Brock K, Moore, M M
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
Mutat Res
1989
222:191-203
PubMed ID: 2466200
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2618
Furuno-Fukushi I, Ueno, A M, Matsudaira H
Mutation induction by very low dose rate gamma rays in cultured mouse leukemia cells L5178Y.
Radiat Res
1988
115:273-80
PubMed ID: 3406368
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2624
Hama-Inaba H, Hieda-Shiomi N, Shiomi T, Sato K
Isolation and characterization of mitomycin-C-sensitive mouse lymphoma cell mutants.
Mutat Res
1983
108:405-16
PubMed ID: 6403846
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2626
Sato K, Hieda-Shiomi N, Hama-Inaba H
X-ray-sensitive mutant mouse cells with various sensitivities to chemical mutagens.
Mutat Res
1983
121:281-5
PubMed ID: 6413855
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2622
Shiomi T, Hieda-Shiomi N, Sato K
Isolation of UV-sensitive mutants of mouse L5178Y cells by a cell suspension spotting method.
Somatic Cell Genet
1982
8:329-345
PubMed ID: 7112349
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2623
Shiomi T, Hieda-Shiomi N, Sato K
A novel mutant of mouse lymphoma cells sensitive to alkylating agents and caffeine.
Mutat Res
1982
103:61-9
PubMed ID: 7057785
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2621
Sato K, Hieda N
Isolation of a mammalian cell mutant sensitive to 4-nitroquinoline-1-oxide.
Int J Radiat Biol Relat Stud Phys Chem Med
1979
35:83-7
PubMed ID: 109406
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2625
Sato K, Hieda N
Isolation and characterization of a mutant mouse lymphoma cell sensitive to methyl methanesulfonate and X rays.
Radiat Res
1979
78:167-71
PubMed ID: 221956
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238
Suzuki N, Okada S
Isolation of nutrient deficient mutants and quantitative mutation assay by reversion of alanine-requiring L5178Y cells.
Mutat Res
1976
34:489-505
PubMed ID: 817197
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2620
Alexander, P.
Mouse lymphoma cells with different radiosensitivities.
Nature
1961
192:572-573
PubMed ID: 13860357
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237
FISCHER, G A, WELCH, A D
Effect of citrovorum factor and peptones on mouse leukemia cells L-5178 in tissue culture.
Science
1957
126:1018-9
PubMed ID: 13486055
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| User's Publication |
|
11216
Amiri Moghani AR, Sharma MK, Matsumoto Y.
In cellulo phosphorylation of DNA double-strand break repair protein XRCC4 on Ser260 by DNA-PK.
J. Radiat. Res.
2018
PubMed ID: 30247612
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3032
Wada, Seiichi, Kurahayashi, Hidemitsu, Kobayashi, Yasuhiko, Funayama, Tomoo, Yamamoto, Kazuo, Natsuhori, Masahiro, Ito, Nobuhiko
The relationship between cellular radiosensitivity and radiation-induced DNA damage measured by the comet assay.
J Vet Med Sci
2003
65:471-7
PubMed ID: 12736429
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3031
Wada, Seiichi, Khoa, Tran Van, Kobayashi, Yasuhiko, Funayama, Tomoo, Yamamoto, Kazuo, Natsuhori, Masahiro, Ito, Nobuhiko
Detection of radiation-induced apoptosis using the comet assay.
J Vet Med Sci
2003
65:1161-6
PubMed ID: 14665742
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4076
Nonaka M, Ikeda H, Inokuchi T.
Effect of combined photodynamic and chemotherapeutic treatment on lymphoma cells in vitro
Cancer Lett
2002
184(2):171-8
PubMed ID: 12127689
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2380
Yokota S, Yanagi H, Yura T, Kubota H
Cytosolic chaperonin is up-regulated during cell growth. Preferential expression and binding to tubulin at G(1)/S transition through early S phase.
J Biol Chem
1999
274:37070-8
PubMed ID: 10601265
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4067
TAKAHIRO SUZUKI TORU EZURE MASARU ISHIDA
In‐vitro Antitumour Activity of Extracts From Cyanobacteria
Pharmacy and Pharmacology Communications
1999
5:619-622
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2359
Suzuki T, Ezure T, Ishida M
Synergistic effects of some pairs of antioxidants and related agents on mouse leukaemia L5178Y cell growth in-vitro
J Pharm Pharmacol
1998
50:1173-1177
PubMed ID: 9821666
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1944
Suzuki, T., and Ishida, M.
Application of Neural Networks in Quantitative Structure-activity Relationships of Cytotoxicity of Antioxidants
Pharmaceutical Sciences
1995
1:297-300
|
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5411
Nakamura M, Sakanaka C, Aoki Y, Ogasawara H, Tsuji T, Kodama H, Matsumoto T, Shimizu T, Noma M.
Identification of two isoforms of mouse neuropeptide Y-Y1 receptor generated by alternative splicing. Isolation, genomic structure, and functional expression of the receptors.
J Biol Chem
1995
270(50):30102-10
PubMed ID: 8530415
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1850
Suzuki Takahiro, Ohtaguchi Kazuhisa and Koide Kozo
Modelling the cytotoxicity of antioxidants to mouse leukaemia L5178Y cells in vitro
Pharmaceutical Science Communications
1994
4:171-181
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1772
Suzuki, T., Ohtaguchi, K. and Koide, K.
Cell Growth Inhibition in Mouse Leukemia L5178Y Cells In Vitro by Crude Extracts from Freshwater Blue-Green Algae
J Chemical Engineering
1993
26:463-464
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6251
Hye-Sook Chang , Daiji Endoh, Yushi Ishida, Hiroyuki Takahashi, Shuji Ozawa, Masanobu Hayashi, Akira Yabuki, Osamu Yamato
Radioprotective effect of alk(en)yl thiosulfates derived from allium vegetables against DNA damage caused by X-ray irradiation in cultured cells: antiradiation potential of onions and garlic
ScientificWorldJournal
2012
846750
PubMed ID: 22919357
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5901
Masanobu Kawanishi, Katsuyuki Okuyama, Kazunori Shiraishi, Yatsuka Matsuda, Ryoichi Taniguchi, Nobuyuki Shiomi, Morio Yonezawa, Takashi Yagi
Growth retardation of Paramecium and mouse cells by shielding them from background radiation
J Radiat Res
2012
53(3):404-10
PubMed ID: 22739010
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