利用者成果(英) |
22181
Tomihari M, Iwasaki M, Ishikawa M.
Propranolol and landiolol inhibit cell proliferation enhanced by noradrenaline in human lung adenocarcinoma cells.
Biomed Res
2024:253-259
45(6)
PubMed ID: 39581614
DOI: 10.2220/biomedres.45.253
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21542
Morihiro K, Morita S, Harada N, Baba M, Yum J, Naito M, Miyata K, Nagae G, Okamoto A.
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality.
J Am Chem Soc
2024
PubMed ID: 38170469
DOI: 10.1021/jacs.3c09524
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21618
Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, Ohama T.
PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
J Biol Chem
2024
300(1):105584
PubMed ID: 38141761
DOI: 10.1016/j.jbc.2023.105584
|
21652
Yoshida T, Goto K, Kodama A, Bolidong D, Seto T, Hanayama R.
Extracellular vesicles promote silica nanoparticle aggregation that inhibits silica-induced cytotoxicity.
Arch Biochem Biophys
2024
755:109964
PubMed ID: 38527699
DOI: 10.1016/j.abb.2024.109964
|
21806
Suzuki M, Kobayashi H, Hara D, Hanaoka H.
Elimination of radiation-induced senescent cancer cells and stromal cells in vitro by near-infrared photoimmunotherapy.
Cancer Med
2024
13(12):e7381
PubMed ID: 38888415
DOI: 10.1002/cam4.7381
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21821
Ito T, Tamashiro S, Okuda H, Yamazoe E, Tahara K.
Cryomilled electrospun nanofiber mats containing d-mannitol exhibit suitable for aerosol delivery of proteins.
Int J Pharm
2024
661:124425
PubMed ID: 38971509
DOI: 10.1016/j.ijpharm.2024.124425
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21833
Hata M, Kadoya Y, Ueno J, Taki M, Kodera M.
Dicopper Complexes of p-Cresol-2,6-bis(amide-tether-dpa4-X) (X = MeO and Cl): Selective ROS Generation and Cytotoxicity Enhancement Controlled by Electronic and Hydrophobic Effects of the MeO and Cl Groups.
Inorg Chem
2024
PubMed ID: 39011904
DOI: 10.1021/acs.inorgchem.4c01072
|
21878
Kimura R, Hashimoto S, Eguchi H, Morikawa Y, Suenami K, Yoshino Y, Matsunaga T, Endo S, Ikari A.
Enhancement of chemoresistance by claudin-1-mediated formation of amino acid barriers in human lung adenocarcinoma A549 cells.
Arch Biochem Biophys
2024
110106
PubMed ID: 39067558
DOI: 10.1016/j.abb.2024.110106
|
21889
Nii T, Hijii S, Kaneko R, Tanito K, Yamanaka K, Kishimura A, Mori T, Katayama Y.
In vitro evaluation of novel SN-38 prodrug activated by α-rhamnosidase of exogenous enzyme.
Anal Sci
2024
40(8):1529-1535
PubMed ID: 38748393
DOI: 10.1007/s44211-024-00593-9
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22013
Takahashi K, Tanaka T, Ishihara A, Ohta T.
Strobilurin X acts as an anticancer drug by inhibiting protein synthesis and suppressing mitochondrial respiratory chain activity.
Discov Oncol
2024
15(1):177
PubMed ID: 38769217
DOI: 10.1007/s12672-024-01041-w
|
22182
Pustimbara A, Umami RW, Prakoso NM, Rozaliyani A, Zaini J, Dwiranti A, Ogura SI, Bowolaksono A.
Hemin Promotes Higher Effectiveness of Aminolevulinic-Photodynamic Therapy (ALA-PDT) in A549 Lung Cancer Cell Line by Interrupting ABCG2 Expression.
Med Sci (Basel)
2024
12(4)
PubMed ID: 39584916
DOI: 10.3390/medsci12040066
|
17622
Maruyama S, Sakabe N, Ito C, Shimoyama Y, Sato S, Ikeda K.
Effect of Specimen Processing Technique on Cell Detection and Classification by Artificial Intelligence
Am J Clin Pathol
2023
aqac178
PubMed ID: 36933198
DOI: 10.1093/ajcp/aqac178
|
17769
Primadharsini PP, Nagashima S, Tanaka T, Jirintai S, Takahashi M, Murata K, Okamoto H.
Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone
Viruses
2023
15(4):845
PubMed ID: 37112827
DOI: 10.3390/v15040845
|
17785
Ikeda K, Sakabe N, Maruyama S, Ito C, Shimoyama Y, Oboshi W, Komene T, Yamaguchi Y, Sato S, Nagata K.
Relationship between a deep learning model and liquid-based cytological processing techniques
Cytopathology
2023
Apr 13
PubMed ID: 37051774
DOI: 10.1111/cyt.13235
|
17792
Ryo Doge, Yuki Nishino, Akiko Saito
Fluorinated Derivatives of Digalloyl-Flavan-3-ol Induce Autophagic Cell Death by Forming Granular Aggregates Containing Mitochondria
BioChem
2023
3:61-77
DOI: 10.3390/biochem3020005
|
17808
Sato Y, Yoshino H, Sato K, Kashiwakura I, Tsuruga E.
DAP3-mediated cell cycle regulation and its association with radioresistance in human lung adenocarcinoma cell lines
J Radiat Res
2023
rrad016
PubMed ID: 37023702
DOI: 10.1093/jrr/rrad016
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17814
Tamai M, Taba S, Mise T, Yamashita M, Ishikawa H, Shintake T.
Ethanol vapor inhalation treatment inhibits lethal respiratory viral infection with Influenza A
J Infect Dis
2023
jiad089
PubMed ID: 37101418
DOI: 10.1093/infdis/jiad089
|
17816
Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, William Ewan Hume, Hisashi Doi, Yasuyoshi Watanabe
In vitro evaluation of (S)-2-amino-3-[3-(2-18F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid (18F-FIMP) as a positron emission tomography probe for imaging amino acid transporters
EJNMMI Research
2023
13
PubMed ID: 37115356
DOI: 10.1186/s13550-023-00988-1
|
19547
Yang J, Liu L, Oda Y, Wada K, Ago M, Matsuda S, Hattori M, Goto T, Ishibashi S, Kawashima-Sonoyama Y, Matsuzaki Y, Taketani T.
Extracellular Vesicles and Cx43-Gap Junction Channels Are the Main Routes for Mitochondrial Transfer from Ultra-Purified Mesenchymal Stem Cells, RECs
Int J Mol Sci
2023
24(12):10294
PubMed ID: 37373439
DOI: 10.3390/ijms241210294
|
19548
Morita TY, Yu J, Kashima Y, Kamata R, Yamamoto G, Minamide T, Mashima C, Yoshiya M, Sakae Y, Yamauchi T, Hakozaki Y, Kageyama SI, Nakamura A, Lightcap E, Tanaka K, Niu H, Kannan K, Ohashi A.
CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade
Nat Commun
2023
14(1):7490
PubMed ID: 37980406
DOI: 10.1038/s41467-023-43274-3
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19549
Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
Proc Natl Acad Sci U S A
2023
120(42):e2304139120
PubMed ID: 37831739
DOI: 10.1073/pnas.2304139120
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19550
Oka N, Shimada K, Ishii A, Kobayashi N, Kondo K.
SARS-CoV-2 S1 protein causes brain inflammation by reducing intracerebral acetylcholine production
iScience
2023
26(6):106954
PubMed ID: 37275532
DOI: 10.1016/j.isci.2023.106954
|
19554
Amma C, Inomata Y, Kohno R, Satake M, Furukawa A, Nagata Y, Sugiyama H, Seto T, Suzuki R.
Copper in airborne fine particulate matter (PM2.5) from urban sites causes the upregulation of pro-inflammatory cytokine IL-8 in human lung epithelial A549 cells
Environ Geochem Health
2023
45(8):5879-5891
PubMed ID: 37179508
DOI: 10.1007/s10653-023-01599-4
|
19555
Kobayashi A, Hiroyama Y, Mamiya T, Oikawa M, Konishi T.
The COX-2/PGE2 Response Pathway Upregulates Radioresistance in A549 Human Lung Cancer Cells through Radiation-Induced Bystander Signaling
Biology (Basel)
2023
12(11):1368
PubMed ID: 37997966
DOI: 10.3390/biology12111368
|
19605
Zhang D, Shimokawa T, Guo Q, Dan S, Miki Y, Sunada S.
Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break
Cancer Sci
2023
114(3):1108-1117.
PubMed ID: 36385507
DOI: 10.1111/cas.15659
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19918
Horie M, Fujita K, Endoh S, Sugino S, Maru J, Moriyama A, Ogura I.
Contaminant microorganisms in the in vitro evaluation of cellular responses of cellulose nanofibers and their microbial inactivation using gamma irradiation
Toxicol Mech Methods
2023
33(9):741-754
PubMed ID: 37496379
DOI: 10.1080/15376516.2023.2238061
|
19960
Nakano M, Sakamoto T, Kitano Y, Bono H, Simpson RJ, Tabunoki H.
An extract from the frass of swallowtail butterfly (Papilio machaon) larvae inhibits HCT116 colon cancer cell proliferation but not other cancer cell types
BMC Genomics
2023
24(1):735
PubMed ID: 38049715
DOI: 10.1186/s12864-023-09841-0
|
19976
Gunasekaran P, Hwang YS, Lee GH, Park J, Kim JG, La YK, Park NY, Kothandaraman R, Yim MS, Choi J, Kim HN, Park IY, Lee SJ, Kim MH, Cha-Molstad H, Shin SY, Ryu EK, Bang JK.
Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer
J Med Chem
2023
Dec 17
PubMed ID: 38105611
DOI: 10.1021/acs.jmedchem.3c01493
|
21065
Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
J Am Chem Soc
2023
145(1):135-142
PubMed ID: 36538570
DOI: 10.1021/jacs.2c08974
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21080
Miura K, Koyanagi-Aoi M, Maniwa Y, Aoi T.
Chorioallantoic membrane assay revealed the role of TIPARP (2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible poly (ADP-ribose) polymerase) in lung adenocarcinoma-induced angiogenesis.
Cancer Cell Int
2023
23(1):34
PubMed ID: 36841751
DOI: 10.1186/s12935-023-02870-5
|
21168
Yang J, Liu L, Oda Y, Wada K, Ago M, Matsuda S, Hattori M, Goto T, Kawashima Y, Matsuzaki Y, Taketani T.
Highly-purified rapidly expanding clones, RECs, are superior for functional-mitochondrial transfer.
Stem Cell Res Ther
2023
14(1):40
PubMed ID: 36927781
DOI: 10.1186/s13287-023-03274-y
|
21185
Sugimoto Y, Suga T, Umino M, Yamayoshi A, Mukai H, Kawakami S.
Investigation of enhanced intracellular delivery of nanomaterials modified with novel cell-penetrating zwitterionic peptide-lipid derivatives.
Drug Deliv
2023
30(1):2191891
PubMed ID: 36964673
DOI: 10.1080/10717544.2023.2191891
|
21259
Takata J, Kiura K, Nakasuka T, Hirabae A, Arimoto-Kobayashi S.
Chemo-preventive effects and antitumorigenic mechanisms of beer and nonalcoholic beer toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) - induced lung tumorigenesis in A/J mice.
Genes Environ
2023
45(1):19
PubMed ID: 37280663
DOI: 10.1186/s41021-023-00276-3
|
21379
Hata M, Ueno J, Hitomi Y, Kodera M.
Roles of DNA Target in Cancer Cell-Selective Cytotoxicity by Dicopper Complexes with DNA Target/Ligand Conjugates.
ACS Omega
2023
8(31):28690-28701
PubMed ID: 37576680
DOI: 10.1021/acsomega.3c03387
|
21380
Tagawa Y, Sakagami H, Tanuma SI, Amano S, Uota S, Bandow K, Tomomura M, Uesawa Y, Takao K, Sugita Y, Yamamoto N, Sakashita H, Nakakaji R, Koizumi T, Mitsudo K, Tohnai I.
Potentiation of Anticancer Activity of G2/M Blockers by Mild Hyperthermia.
Anticancer Res
2023
43(8):3429-3439
PubMed ID: 37500171
DOI: 10.21873/anticanres.16518
|
21514
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N.
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nat Commun
2023
14(1):8095
PubMed ID: 38092728
DOI: 10.1038/s41467-023-43630-3
|
21516
Wang H, Zhang H, Tamura R, Da B, Abdellatef SA, Watanabe I, Ishida N, Fujita D, Hanagata N, Nakagawa T, Nakanishi J.
Mapping stress inside living cells by atomic force microscopy in response to environmental stimuli.
Sci Technol Adv Mater
2023
24(1):2265434
PubMed ID: 37867575
DOI: 10.1080/14686996.2023.2265434
|
21526
Pan Y, Suzuki T, Sakai K, Hirano Y, Ikeda H, Hattori A, Dohmae N, Nishio K, Kakeya H.
Bisabosqual A: A novel asparagine synthetase inhibitor suppressing the proliferation and migration of human non-small cell lung cancer A549 cells.
Eur J Pharmacol
2023
960:176156
PubMed ID: 38059445
DOI: 10.1016/j.ejphar.2023.176156
|
21547
Autsavapromporn N, Kobayashi A, Liu C, Duangya A, Oikawa M, Tengku Ahmad TA, Konishi T.
Primary and Secondary Bystander Effects of Proton Microbeam Irradiation on Human Lung Cancer Cells under Hypoxic Conditions.
Biology (Basel)
2023
12(12)
PubMed ID: 38132311
DOI: 10.3390/biology12121485
|
17494
Maeda A, Fujimura T, Hirakawa N, Baba K, Kawamoto S.
A Methoxyflavanone from Perilla frutescens Induces Cellular Senescence in A549 Human Lung Adenocarcinoma Cells but Not in Normal Human Bronchial Epithelial Cells
Biol Pharm Bull
2022
45(10):1581-1584
PubMed ID: 35979561
DOI: 10.1248/bpb.b22-00310
|
17595
Maki M, JeongMin H, Nakagawa T, Kawai H, Sakamoto N, Sato Y, Noguchi M.
Aberrant OCIAD2 demethylation in lung adenocarcinoma is associated with outcome
Pathol Int
2022
72(10):496-505
PubMed ID: 35920378
DOI: 10.1111/pin.13262
|
17647
Tamari S, Menju T, Toyazaki T, Miyamoto H, Chiba N, Noguchi M, Ishikawa H, Miyata R, Kayawake H, Tanaka S, Yamada Y, Yutaka Y, Nakajima D, Ohsumi A, Hamaji M, Date H.
Nrf2/p‑Fyn/ABCB1 axis accompanied by p‑Fyn nuclear accumulation plays pivotal roles in vinorelbine resistance in non‑small cell lung cancer
Oncol Rep
2022
48(4):171
PubMed ID: 35959810
DOI: 10.3892/or.2022.8386
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18224
Sadahiro Y, Hitora Y, Kimura I, Hitora-Imamura N, Onodera R, Motoyama K, Tsukamoto S.
Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53
Chem Res Toxicol
2022
35(9):1598-1603
PubMed ID: 36027604
DOI: 10.1021/acs.chemrestox.2c00202
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13435
Funato N, Yanagisawa H.
TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties
Sci Rep
2022
12(1):20188
PubMed ID: 36418889
DOI: 10.1038/s41598-022-24604-9
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20214
Ando H, Murakami Y, Eshima K, Ishida T.
A novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML).
Cancer Rep (Hoboken)
2022
e1485
PubMed ID: 34173723
DOI: 10.1002/cnr2.1485
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20391
Fardous J, Omoso Y, Yoshida K, Ono F, Patwary MKA, Ijima H.
Gel-in-water nanodispersion for potential application in intravenous delivery of anticancer drugs.
J Biosci Bioeng
2022
PubMed ID: 34789413
DOI: 10.1016/j.jbiosc.2021.10.001
|
20408
Ikeda K, Oboshi W, Hashimoto Y, Komene T, Yamaguchi Y, Sato S, Maruyama S, Furukawa N, Sakabe N, Nagata K.
Characterizing the Effect of Processing Technique and Solution Type on Cytomorphology Using Liquid-Based Cytology.
Acta Cytol
2022
1-6
PubMed ID: 34644702
DOI: 10.1159/000519335
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20410
Autsavapromporn N, Kobayashi A, Liu C, Jaikang C, Ahmad TAT, Oikawa M, Konishi T.
Hypoxia and Proton microbeam: Role of Gap Junction Intercellular Communication in Inducing Bystander Responses on Human Lung Cancer Cells and Normal Cells.
Radiat Res
2022
PubMed ID: 34634126
DOI: 10.1667/RADE-21-00112.1
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20486
Horibe S, Ishikawa K, Nakada K, Wake M, Takeda N, Tanaka T, Kawauchi S, Sasaki N, Rikitake Y.
Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells.
Oncol Rep
2022
47(2)
PubMed ID: 34935060
DOI: 10.3892/or.2021.8243
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16353
Tsujiya Y, Hasegawa A, Yamamori M, Okamura N.
Troglitazone-Induced Autophagic Cytotoxicity in Lung Adenocarcinoma Cell Lines
Biol Pharm Bull
2022
45(3):276-283
PubMed ID: 35228393
DOI: 10.1248/bpb.b21-00785
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20590
Hagimori M, Hara F, Mizuyama N, Fujino T, Saji H, Mukai T.
High-Affinity Ratiometric Fluorescence Probe Based on 6-Amino-2,2'-Bipyridine Scaffold for Endogenous Zn2+ and Its Application to Living Cells.
Molecules
2022
27(4)
PubMed ID: 35209077
DOI: 10.3390/molecules27041287
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20595
Matsushige T, Sakabe T, Umekita Y.
Investigation of the Subcellular Localization-Dependent Anti- or Pro-Tumor Functions of Maspin in Human Lung Adenocarcinoma Cell Line.
Yonago Acta Med
2022
65(1):44-52
PubMed ID: 35221759
DOI: 10.33160/yam.2022.02.006
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20613
Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.
Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.
Analyst
2022
PubMed ID: 35297918
DOI: 10.1039/d2an00052k
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20657
Fukumoto Y, Matsuhashi K, Tanaka YK, Suzuki N, Ogra Y.
Band 3/anion exchanger 1/solute carrier family 4 member 1 expression as determinant of cellular sensitivity to selenite exposure.
Biochem Biophys Rep
2022
29:101223
PubMed ID: 35146136
DOI: 10.1016/j.bbrep.2022.101223
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20674
Ito K, Nagata K, Ohta S, Matsuda Y, Ukai T, Yasuda I, Ota A, Kobayashi R, Kabata M, Sankoda N, Maeda T, Woltjen K, Yang L, Maruyama R, Katayama R, Yamamoto T, Yamada Y.
The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
Cell Rep
2022
39(4):110721
PubMed ID: 35476996
DOI: 10.1016/j.celrep.2022.110721
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20684
Fujimoto M, Higashiyama R, Yasui H, Yamashita K, Inanami O.
Preclinical studies for improving radiosensitivity of non-small cell lung cancer cell lines by combining glutaminase inhibition and senolysis.
Transl Oncol
2022
21:101431
PubMed ID: 35452996
DOI: 10.1016/j.tranon.2022.101431
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16485
Toma T, Tateishi H, Kawakami K, Ali TFS, Kamo M, Monde K, Nakashima Y, Fujita M, Otsuka M.
Novel Inhibitor for Downstream Targeting of Transforming Growth Factor-β Signaling to Suppress Epithelial to Mesenchymal Transition and Cell Migration
Int J Mol Sci
2022
23(9):5047
PubMed ID: 35563439
DOI: 10.3390/ijms23095047
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16496
Siswanto FM, Tamura A, Sakuma R, Imaoka S.
Yeast β-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway
Mol Pharmacol
2022
101(4):257-273
PubMed ID: 35193967
DOI: 10.1124/molpharm.121.000475
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16710
Alaa N. Hassan, Tsugumasa Toma, Halilibrahim Ciftci, Tanima Biswas, Yurika Tahara, Mohamed O. Radwan, Hiroshi Tateishi, Mikako Fujita, Masami Otsuka
A vitamin D C/D ring-derived compound with cytotoxicity
Medicinal Chemistry Research
2022
1120-1125
DOI: 10.1007/s00044-021-02842-2
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20799
Fujimoto M, Takii R, Matsumoto M, Okada M, Nakayama KI, Nakato R, Fujiki K, Shirahige K, Nakai A.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.
Nat Commun
2022
13(1):4355
PubMed ID: 35906200
DOI: 10.1038/s41467-022-32034-4
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20808
Riko Nakagawa, Hiroshi Tateishi, Mohamed O. Radwan, Takuma Chinen, Halilibrahim Ciftci, Kana Iwamaru, Nanami Baba, Yuna Tominaga, Ryoko Koga, Tsugumasa Toma, Jun-ichiro Inoue, Kazuo Umezawa, Mikako Fujita, Masami Otsuka
A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity
Chemical and Pharmaceutical Bulletin
2022
477-482
PubMed ID: 35786566
DOI: 10.1248/cpb.c21-01087
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16959
Tsugumasa Toma, Junpei Yamashita, Mohamed O. Radwan, Mostafa M. Badran, Takuya Masunaga, Masahiro Kamo, Ryoko Koga, Yoshinari Okamoto, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
Tranilast-tyrosine hybrid molecule exhibits dual activity: suppression of epithelial-mesenchymal transition and induction of cytotoxicity in cancer cells
Medicinal Chemistry Research
2022
31:1584-1593
DOI: 10.1007/s00044-022-02939-2
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20884
Shindo A, Kusano M, Sakagami H, Amano S, Inomata M, Abe M, Okazawa M, Ooka T.
Comparison of UVC Sensitivity and Dectin-2 Expression Between Malignant and Non-malignant Cells.
In Vivo
2022
36(5):2116-2125
PubMed ID: 36099100
DOI: 10.21873/invivo.12937
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20896
Ikeda K, Sakabe N, Maruyama S, Ito C, Shimoyama Y, Sato S, Nagata K.
Relationship between Liquid-Based Cytology Preservative Solutions and Artificial Intelligence: Liquid-Based Cytology Specimen Cell Detection Using YOLOv5 Deep Convolutional Neural Network.
Acta Cytol
2022
1-9
PubMed ID: 36067744
DOI: 10.1159/000526098
|
20912
Kotani N, Nakano T, Kuwahara R.
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.
J Biol Chem
2022
298(11):102500
PubMed ID: 36152751
DOI: 10.1016/j.jbc.2022.102500
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20963
Takata J, Miyake N, Saiki Y, Tada M, Sasaki K, Kubo T, Kiura K, Arimoto-Kobayashi S.
Chemopreventive effects and anti-tumorigenic mechanisms of Actinidia arguta, known as sarunashi in Japan toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)- induced lung tumorigenesis in a/J mouse.
Genes Environ
2022
44(1):26
PubMed ID: 36494703
DOI: 10.1186/s41021-022-00255-0
|
12851
Kamo M, Ito M, Toma T, Gotoh H, Shimozono R, Nakagawa R, Koga R, Monde K, Tateishi H, Misumi S, Otsuka M, Fujita M.
Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M
Bioorg Chem
2021
107:104627
PubMed ID: 33476868
DOI: 10.1016/j.bioorg.2021.104627
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13332
Hase H, Aoki M, Matsumoto K, Nakai S, Nagata T, Takeda A, Ueda K, Minami K, Kitae K, Jingushi K, Ueda Y, Yamamoto M, Furukawa T, Sato M, Tsujikawa K.
Cancer type‑SLCO1B3 promotes epithelial‑mesenchymal transition resulting in the tumour progression of non‑small cell lung cancer.
Oncol Rep
2021
PubMed ID: 33155667
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GP96 Drives Exacerbation of Secondary Bacterial Pneumonia following Influenza A Virus Infection
mBio
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Chemopreventive effects and anti-tumorigenic mechanisms of 2,6-dimethoxy-1,4-benzoquinone, a constituent of Vitis coignetiae Pulliat (crimson glory vine, known as yamabudo in Japan), toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.
Food Chem Toxicol
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Design, synthesis, and evaluation of a novel prodrug, a S-trityl-l-cysteine derivative targeting kinesin spindle protein.
Eur J Med Chem
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Diosgenin suppresses COX-2 and mPGES-1 via GR and improves LPS-induced liver injury in mouse
Prostaglandins Other Lipid Mediat
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LAT1 inhibitor JPH203 sensitizes cancer cells to radiation by enhancing radiation-induced cellular senescence
Transl Oncol
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DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency
Nat Commun
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Air-liquid interphase culture confers SARS-CoV-2 susceptibility to A549 alveolar epithelial cells.
Biochem Biophys Res Commun
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Lurasidone Sensitizes Cancer Cells to Osimertinib by Inducing Autophagy and Reduction of Survivin.
Anticancer Res
2021
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Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.
Biomolecules
2021
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High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.
Heliyon
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Shindo Y, Arai W, Konno T, Kohno T, Kodera Y, Chiba H, Miyajima M, Sakuma Y, Watanabe A, Kojima T.
Effects of histone deacetylase inhibitors Tricostatin A and Quisinostat on tight junction proteins of human lung adenocarcinoma A549 cells and normal lung epithelial cells.
Histochem Cell Biol
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5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience
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SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis
Nat Commun
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Takasaka M, Kobayashi S, Usui Y, Haniu H, Tsuruoka S, Aoki K, Saito N.
Biokinetic Evaluation of Contrast Media Loaded Carbon Nanotubes Using a Radiographic Device.
Toxics
2021
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Increased expression of REV7 in small cell lung carcinomas and its association with tumor cell survival and proliferation
Pathol Int
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DAP3 Is Involved in Modulation of Cellular Radiation Response by RIG-I-Like Receptor Agonist in Human Lung Adenocarcinoma Cells
Int J Mol Sci
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22(1):420
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Jeongmin Hong, Aya Shiba‐Ishii, Yunjung Kim, Masayuki Noguchi, Noriaki Sakamoto
Ovarian carcinoma immunoreactive antigen domain 2 controls mitochondrial apoptosis in lung adenocarcinoma
Cancer Sci
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Not Only Hypoxia- but Radiation-Induced Epithelial-Mesenchymal Transition Is Modulated by Hypoxia-Inducible Factor 1 in A549 Lung Cancer Cells
Folia Biol (Praha)
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Upregulation of Chemoresistance by Mg 2+ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells
Cells
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Takeru Yamazaki, Kohe Arima, Riku Kubota, Kiyoshi Sato, Hiroyoshi Kawakami
Preparation of Mitochondria‐ and Epigenetics‐Targeting Nanoparticles for Suppression of Cancer Metastasis
Particle & Particle Systems Characterization
2021
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Hirofumi Kurita, Yoshie Minamijima, Kazunori Takashima
Characterization of intracellular reactive species production stimulated by cold atmospheric pressure plasma irradiation
Int. J. Plasma Environ. Sci. Technol
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Claudin-2 binding peptides, VPDSM and DSMKF, down-regulate claudin-2 expression and anticancer resistance in human lung adenocarcinoma A549 cells.
Biochim Biophys Acta Mol Cell Res.
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Growth Differentiation Factor 15 Facilitates Lung Fibrosis by Activating Macrophages and Fibroblasts
Exp Cell Res
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Keisuke Toda, Mai Ueyama, Shomu Tanaka, Izumi Tsukayama, Takuto Mega, Yuka Konoike, Asako Tamenobu, Februadi Bastian, Iria Akai, Hideyuki Ito, Yuki Kawakami, Yoshitaka Takahashi, Toshiko Suzuki-Yamamoto
Ellagitannins From Punica granatum Leaves Suppress Microsomal Prostaglandin E synthase-1 Expression and Induce Lung Cancer Cells to Undergo Apoptosis
Biosci Biotechnol Biochem
2020
84(4):757-763
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Enhancement of membrane lipid peroxidation in lung cancer cells irradiated with monoenergetic X-rays at the K-shell resonance absorption peak of phosphorus.
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Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.
Biochim Biophys Acta Mol Cell Biol Lipids
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Morita S, Horii T, Kimura M, Hatada I.
Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9-SunTag Platform
Int J Mol Sci
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Effect of transforming growth factor-β1 on functional expression of monocarboxylate transporter 1 in alveolar epithelial A549 cells
Naunyn Schmiedebergs Arch Pharmacol
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Dukaew N, Konishi T, Chairatvit K, Autsavapromporn N, Soonthornchareonnon N, Wongnoppavich A.
Enhancement of Radiosensitivity by Eurycomalactone in Human NSCLC Cells Through G₂/M Cell Cycle Arrest and Delayed DNA Double-Strand Break Repair
Oncol Res
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28(2):161-175
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Endo M, Ohba K, Sato S, Yokota Y, Takahashi K.
Increased soluble (pro)renin receptor protein by autophagy inhibition in cultured cancer cells.
Genes Cells
2020
PubMed ID: 32314441
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Eguchi H, Matsunaga T, Endo S, Ichihara K, Ikari A.
Kaempferide Enhances Chemosensitivity of Human Lung Adenocarcinoma A549 Cells Mediated by the Decrease in Phosphorylation of Akt and Claudin-2 Expression.
Nutrients
2020
PubMed ID: 32340376
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Matsumoto Y, Hattori K, Arima H, Motoyama K, Higashi T, Ishikawa H, Fukumitsu N, Aihara T, Nakai K, Kumada H, Sakurai H.
Folate-appended cyclodextrin improves the intratumoral accumulation of existing boron compounds.
Appl Radiat Isot
2020
PubMed ID: 32561042
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Ihara H, Mitsuishi Y, Kato M, Takahashi F, Tajima K, Hayashi T, Hidayat M, Winardi W, Wirawan A, Hayakawa D, Kanamori K, Matsumoto N, Yae T, Sato T, Sasaki S, Takamochi K, Suehara Y, Ogura D, Niwa SI, Suzuki K, Takahashi K.
Nintedanib inhibits epithelial-mesenchymal transition in A549 alveolar epithelial cells through regulation of the TGF-β/Smad pathway.
Respir Investig
2020
PubMed ID: 32359980
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Kurita H, Haruta N, Uchihashi Y, Seto T, Takashima K.
Strand breaks and chemical modification of intracellular DNA induced by cold atmospheric pressure plasma irradiation.
PLoS One
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PubMed ID: 32374749
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Ahmed S, Kobayashi H, Afroz T, Ma N, Oikawa S, Kawanishi S, Murata M, Hiraku Y.
Nitrative DNA damage in lung epithelial cells exposed to indium nanoparticles and indium ions.
Sci Rep
2020
PubMed ID: 32612147
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Kikuchi N, Soga T, Nomura M, Sato T, Sakamoto Y, Tanaka R, Abe J, Morita M, Shima H, Okada Y, Tanuma N.
Comparison of the ischemic and non-ischemic lung cancer metabolome reveals hyper activity of the TCA cycle and autophagy.
Biochem Biophys Res Commun
2020
PubMed ID: 32828300
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Togami K, Maruta Y, Nanbu M, Tada H, Chono S.
Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycin-induced pulmonary fibrosis.
Drug Dev Ind Pharm
2020
PubMed ID: 32940095
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Inoue Y, Okamoto T, Honda T, Nukui Y, Akashi T, Takemura T, Tozuka M, Miyazaki Y.
Disruption in the balance between apolipoprotein A-I and mast cell chymase in chronic hypersensitivity pneumonitis.
Immun Inflamm Dis
2020
PubMed ID: 33016012
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Doi T, Ogawa H, Tanaka Y, Hayashi Y, Maniwa Y.
Bex1 significantly contributes to the proliferation and invasiveness of malignant tumor cells.
Oncol Lett
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PubMed ID: 33133262
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Chinnathambi S, Hanagata N, Yamazaki T, Shirahata N.
Nano-Bio Interaction between Blood Plasma Proteins and Water-Soluble Silicon Quantum Dots with Enabled Cellular Uptake and Minimal Cytotoxicity.
Nanomaterials (Basel)
2020
PubMed ID: 33202926
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Hitomi Fujisaki, Sugiko Futaki, Masashi Yamada, Kiyotoshi Sekiguchi, Toshihiko Hayashi, Shunji Hattori
Adhesion to type I collagen fibrous gels induces E- to N-cadherin switching without other EMT-related phenotypes in lung carcinoma cell A549
bioRxiv
2020
October 04
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RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells
RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells
DNA Repair (Amst)
2020
91-92:102872
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Kenta Shinha, Tatsuto Ono, Ryota Nakazato, Hiroshi Kimura
Combination of a multi-organ microphysiological system (MO–MPS) and a pharmacokinetic-pharmacodynamic (PK–PD) model to evaluate drug–drug interactions (DDI)
Authorea Preprints
2020
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Sato Y, Yoshino H, Tsuruga E, Kashiwakura I.
Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-like Receptor Agonist and Radiation
Curr Cancer Drug Targets
2020
20(5):372-381
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Togami K, Yamaguchi K, Tada H, Chono S.
Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis
Pharmazie
2020
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Eguchi R, Wakabayashi I.
HDGF enhances VEGF‑dependent angiogenesis and FGF‑2 is a VEGF‑independent angiogenic factor in non‑small cell lung cancer
Oncol Rep
2020
44(1):14-28
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Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y.
Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines
Arch Virol
2020
165(1):207-214
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Punzalan LL, Jiang L, Mao D, Mahapatra AD, Sato S, Takemoto Y, Tsujimura M, Kusamori K, Nishikawa M, Zhou L, Uesugi M.
Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library
Cell Chem Biol
2020
27(6):708-718.e1
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Chikuma K, Arima K, Asaba Y, Kubota R, Asayama S, Sato K, Kawakami H.
The potential of lipid-polymer nanoparticles as epigenetic and ROS control approaches for COPD
Free Radic Res
2020
54(11-12):829-840
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Shinha K, Nihei W, Ono T, Nakazato R, Kimura H.
A pharmacokinetic-pharmacodynamic model based on multi-organ-on-a-chip for drug-drug interaction studies.
Biomicrofluidics
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Futami K, Kimoto M, Lim YWS, Hirao I.
Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells.
Mol Ther Nucleic Acids
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Aki T, Unuma K, Noritake K, Hirayama N, Funakoshi T, Uemura K.
Formation of high molecular weight p62 by CORM-3.
PLoS ONE
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Kobayashi A, Autsavapromporn N, Ahmad TAFT, Oikawa M, Homma-Takeda S, Furusawa Y, Wang J, Konishi T.
BYSTANDER WI-38 CELLS MODULATE DNA DOUBLE-STRAND BREAK REPAIR IN MICROBEAM-TARGETED A549 CELLS THROUGH GAP JUNCTION INTERCELLULAR COMMUNICATION.
Radiat Prot Dosimetry
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Halil I. Ciftci, Mohamed O. Radwan, Safiye E. Ozturk, N. Gokce Ulusoy, Ece Sozer, Doha E. Ellakwa, Zeynep Ocak, Mustafa Can, Taha F.S. Ali, Howaida I. Abd-Alla, Nurettin Yayli, Hiroshi Tateishi, Masami Otsuka and Mikako Fujita
Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity
Molecules
2019
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Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
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Sugiyama Y, Shudo T, Hosokawa S, Watanabe A, Nakano M, Kakizuka A.
Emodin, as a mitochondrial uncoupler, induces strong decreases in adenosine triphosphate (ATP) levels and proliferation of B16F10 cells, owing to their poor glycolytic reserve.
Genes Cells
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PubMed ID: 31234244
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Autsavapromporn N, Liu C, Kobayashi A, Ahmad TAFT, Oikawa M, Dukaew N, Wang J, Wongnoppavichb A, Konishic T.
Emerging Role of Secondary Bystander Effects Induced by Fractionated Proton Microbeam Radiation.
Radiat. Res.
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Dr. Ze Yuan, Prof. Toshihiro Nakamura, Dr. Shanmugavel Chinnathambi, Prof. Yanbai Pu, Prof. Naoto Shirahata, Prof. Kiyoto Matsuishi
Facile Formation of Stable Water‐Dispersed Luminescent Silicon Nanocrystals by Laser Processing in Liquid: Toward Fluorescent Labeling for Bio‐Imaging
CHEMNANOMAT
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Sanomachi T, Suzuki S, Togashi K, Seino S, Yoshioka T, Kitanaka C, Okada M, Yamamoto M.
Brexpiprazole Reduces Survivin and Reverses EGFR Tyrosine Kinase Inhibitor Resistance in Lung and Pancreatic Cancer.
Anticancer Res.
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Sanomachi T, Suzuki S, Togashi K, Sugai A, Seino S, Okada M, Yoshioka T, Kitanaka C, Yamamoto M.
Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs.
Cancers (Basel)
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Matsumoto Y, Kuriki H, Kitamura T, Takahashi D, Toshima K.
Total Synthesis and Structure-Activity Relationship Study of Vineomycin A1.
J. Org. Chem.
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Hiromasa Fujita, Katsumi Hirose, Mariko Sato, Ichitaro Fujioka, Tamaki Fujita, Masahiko Aoki, Yoshihiro Takai
Metformin Attenuates Hypoxia-Induced Resistance to Cisplatin in the HepG2 Cell Line
Oncol Lett
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Belgin Sever, Mehlika Dilek Altıntop, Mohamed O Radwan, Ahmet Özdemir, Masami Otsuka, Mikako Fujita, Halil I Ciftci
Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
Eur J Med Chem
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Mutation Research/Genetic Toxicology and Environmental Mutagenesis
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Mar Drugs
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Transl Oncol
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Bioorg Med Chem
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BMC Cancer
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Part Fibre Toxicol
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Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair
Cancer Sci
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Selective DNA Recognition and Cytotoxicity of Water-Soluble Helical Metallosupramolecular Polymers
Bioconjug Chem
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Aripiprazole, an Antipsychotic and Partial Dopamine Agonist, Inhibits Cancer Stem Cells and Reverses Chemoresistance
Anticancer Res
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A Nucleoside Anticancer Drug, 1-(3-C-Ethynyl-β-D-Ribo-Pentofuranosyl)Cytosine, Induces Depth-Dependent Enhancement of Tumor Cell Death in Spread-Out Bragg Peak (SOBP) of Proton Beam
PLoS One
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Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark
Chem Biodivers
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Nanoscience and Nanotechnology Letters
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Development of a Sortase A-mediated Peptide-labeled Liposome Applicable to Drug-delivery Systems.
Anticancer Res
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PLoS One
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Mol Med Rep
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A Theoretical Model for the Hormetic Dose-response Curve for Anticancer Agents
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