User's Publication |
20214
Ando H, Murakami Y, Eshima K, Ishida T.
A novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML).
Cancer Rep (Hoboken)
2022
e1485
PubMed ID: 34173723
|
20391
Fardous J, Omoso Y, Yoshida K, Ono F, Patwary MKA, Ijima H.
Gel-in-water nanodispersion for potential application in intravenous delivery of anticancer drugs.
J Biosci Bioeng
2022
PubMed ID: 34789413
|
20408
Ikeda K, Oboshi W, Hashimoto Y, Komene T, Yamaguchi Y, Sato S, Maruyama S, Furukawa N, Sakabe N, Nagata K.
Characterizing the Effect of Processing Technique and Solution Type on Cytomorphology Using Liquid-Based Cytology.
Acta Cytol
2022
1-6
PubMed ID: 34644702
|
20410
Autsavapromporn N, Kobayashi A, Liu C, Jaikang C, Ahmad TAT, Oikawa M, Konishi T.
Hypoxia and Proton microbeam: Role of Gap Junction Intercellular Communication in Inducing Bystander Responses on Human Lung Cancer Cells and Normal Cells.
Radiat Res
2022
PubMed ID: 34634126
|
20486
Horibe S, Ishikawa K, Nakada K, Wake M, Takeda N, Tanaka T, Kawauchi S, Sasaki N, Rikitake Y.
Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells.
Oncol Rep
2022
47(2)
PubMed ID: 34935060
|
16353
Tsujiya Y, Hasegawa A, Yamamori M, Okamura N.
Troglitazone-Induced Autophagic Cytotoxicity in Lung Adenocarcinoma Cell Lines
Biol Pharm Bull
2022
45(3):276-283
PubMed ID: 35228393
|
20590
Hagimori M, Hara F, Mizuyama N, Fujino T, Saji H, Mukai T.
High-Affinity Ratiometric Fluorescence Probe Based on 6-Amino-2,2'-Bipyridine Scaffold for Endogenous Zn2+ and Its Application to Living Cells.
Molecules
2022
27(4)
PubMed ID: 35209077
|
20595
Matsushige T, Sakabe T, Umekita Y.
Investigation of the Subcellular Localization-Dependent Anti- or Pro-Tumor Functions of Maspin in Human Lung Adenocarcinoma Cell Line.
Yonago Acta Med
2022
65(1):44-52
PubMed ID: 35221759
|
20613
Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.
Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.
Analyst
2022
PubMed ID: 35297918
|
20674
Ito K, Nagata K, Ohta S, Matsuda Y, Ukai T, Yasuda I, Ota A, Kobayashi R, Kabata M, Sankoda N, Maeda T, Woltjen K, Yang L, Maruyama R, Katayama R, Yamamoto T, Yamada Y.
The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
Cell Rep
2022
39(4):110721
PubMed ID: 35476996
|
20684
Fujimoto M, Higashiyama R, Yasui H, Yamashita K, Inanami O.
Preclinical studies for improving radiosensitivity of non-small cell lung cancer cell lines by combining glutaminase inhibition and senolysis.
Transl Oncol
2022
21:101431
PubMed ID: 35452996
|
16485
Toma T, Tateishi H, Kawakami K, Ali TFS, Kamo M, Monde K, Nakashima Y, Fujita M, Otsuka M.
Novel Inhibitor for Downstream Targeting of Transforming Growth Factor-β Signaling to Suppress Epithelial to Mesenchymal Transition and Cell Migration
Int J Mol Sci
2022
23(9):5047
PubMed ID: 35563439
|
16496
Siswanto FM, Tamura A, Sakuma R, Imaoka S.
Yeast β-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway
Mol Pharmacol
2022
101(4):257-273
PubMed ID: 35193967
|
12851
Kamo M, Ito M, Toma T, Gotoh H, Shimozono R, Nakagawa R, Koga R, Monde K, Tateishi H, Misumi S, Otsuka M, Fujita M.
Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M
Bioorg Chem
2021
107:104627
PubMed ID: 33476868
|
13332
Hase H, Aoki M, Matsumoto K, Nakai S, Nagata T, Takeda A, Ueda K, Minami K, Kitae K, Jingushi K, Ueda Y, Yamamoto M, Furukawa T, Sato M, Tsujikawa K.
Cancer type‑SLCO1B3 promotes epithelial‑mesenchymal transition resulting in the tumour progression of non‑small cell lung cancer.
Oncol Rep
2021
PubMed ID: 33155667
|
20016
Matsumoto N, Ebihara M, Oishi S, Fujimoto Y, Okada T, Imamura T.
Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells.
Sci Rep
2021
11(1):1492
PubMed ID: 33452347
|
20076
Anam MB, Istiaq A, Kariya R, Kudo M, Ishtiyaq Ahmad SA, Ito N, Okada S, Ohta K.
Ribosome induces transdifferentiation of A549 and H-111-TC cancer cell lines.
Biochem Biophys Rep
2021
26:100946
PubMed ID: 33644423
|
13718
Aida R, Hagiwara K, Okano K, Nakata K, Obata Y, Yamashita T, Yoshida K, Hagiwara H.
miR-34a-5p might have an important role for inducing apoptosis by down-regulation of SNAI1 in apigenin-treated lung cancer cells
Mol Biol Rep
2021
Mar 6
PubMed ID: 33675467
|
13912
Yamamoto S, Nakanishi J.
Epidermal growth factor-gold nanoparticle conjugates-induced cellular responses: Effect of interfacial parameters between cell and nanoparticle
Anal Sci
2021
37(5):741-745
PubMed ID: 33390415
|
20145
Kiba Y, Oyama R, Misawa S, Tanikawa T, Kitamura M, Suzuki R.
Screening for inhibitory effects of crude drugs on furin-like enzymatic activities.
J Nat Med
2021
PubMed ID: 33928494
|
20147
Kariya Y, Oyama M, Suzuki T, Kariya Y.
αvβ3 Integrin induces partial EMT independent of TGF-β signaling.
Commun Biol
2021
4(1):490
PubMed ID: 33883697
|
14339
Sumitomo T, Nakata M, Nagase S, Takahara Y, Honda-Ogawa M, Mori Y, Akamatsu Y, Yamaguchi M, Okamoto S, Kawabata S.
GP96 Drives Exacerbation of Secondary Bacterial Pneumonia following Influenza A Virus Infection
mBio
2021
e0326920
PubMed ID: 34061598
|
20205
Arimoto-Kobayashi S, Sasaki K, Hida R, Miyake N, Fujii N, Saiki Y, Daimaru K, Nakashima H, Kubo T, Kiura K.
Chemopreventive effects and anti-tumorigenic mechanisms of 2,6-dimethoxy-1,4-benzoquinone, a constituent of Vitis coignetiae Pulliat (crimson glory vine, known as yamabudo in Japan), toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.
Food Chem Toxicol
2021
154:112319
PubMed ID: 34087405
|
20278
Fukai R, Ogo N, Ichida T, Yamane M, Sawada JI, Miyoshi N, Murakami H, Asai A.
Design, synthesis, and evaluation of a novel prodrug, a S-trityl-l-cysteine derivative targeting kinesin spindle protein.
Eur J Med Chem
2021
215:113288
PubMed ID: 33640763
|
15273
Tsukayama I, Mega T, Hojo N, Toda K, Kawakami Y, Takahashi Y, Suzuki-Yamamoto T.
Diosgenin suppresses COX-2 and mPGES-1 via GR and improves LPS-induced liver injury in mouse
Prostaglandins Other Lipid Mediat
2021
Jul 9
PubMed ID: 34252545
|
15490
Bo T, Kobayashi S, Inanami O, Fujii J, Nakajima O, Ito T, Yasui H.
LAT1 inhibitor JPH203 sensitizes cancer cells to radiation by enhancing radiation-induced cellular senescence
Transl Oncol
2021
14(11):101212
PubMed ID: 34461558
|
15504
Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, Ozawa M, Saitou M, Shinkai Y, Yamamoto T, Yamada Y.
DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency
Nat Commun
2021
12(1):5041
PubMed ID: 34413299
|
20362
Sasaki M, Kishimoto M, Itakura Y, Tabata K, Intaruck K, Uemura K, Toba S, Sanaki T, Sato A, Hall WW, Orba Y, Sawa H.
Air-liquid interphase culture confers SARS-CoV-2 susceptibility to A549 alveolar epithelial cells.
Biochem Biophys Res Commun
2021
577:146-151
PubMed ID: 34517212
|
20363
Suzuki S, Yamamoto M, Sanomachi T, Togashi K, Seino S, Sugai A, Yoshioka T, Okada M, Kitanaka C.
Lurasidone Sensitizes Cancer Cells to Osimertinib by Inducing Autophagy and Reduction of Survivin.
Anticancer Res
2021
41(9):4321-4331
PubMed ID: 34475052
|
20367
Kariya Y, Oyama M, Kariya Y, Hashimoto Y.
Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.
Biomolecules
2021
11(9)
PubMed ID: 34572536
|
20406
Sawa C, Yofu S, Kiriyama K, Sutoh K, Saito T, Kishi S, Gunji M, Inoue Y, Sugi M, Shioda S, Honda K.
High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.
Heliyon
2021
7(11):e08318
PubMed ID: 34816032
|
20423
Shindo Y, Arai W, Konno T, Kohno T, Kodera Y, Chiba H, Miyajima M, Sakuma Y, Watanabe A, Kojima T.
Effects of histone deacetylase inhibitors Tricostatin A and Quisinostat on tight junction proteins of human lung adenocarcinoma A549 cells and normal lung epithelial cells.
Histochem Cell Biol
2021
155(6):637-653
PubMed ID: 33974136
|
15879
Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience
2021
24(10):103120
PubMed ID: 34541466
|
15881
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis
Nat Commun
2021
12(1):6602
PubMed ID: 34782627
|
20510
Takasaka M, Kobayashi S, Usui Y, Haniu H, Tsuruoka S, Aoki K, Saito N.
Biokinetic Evaluation of Contrast Media Loaded Carbon Nanotubes Using a Radiographic Device.
Toxics
2021
9(12)
PubMed ID: 34941765
|
16128
Sato Y, Yoshino H, Kashiwakura I, Tsuruga E.
DAP3 Is Involved in Modulation of Cellular Radiation Response by RIG-I-Like Receptor Agonist in Human Lung Adenocarcinoma Cells
Int J Mol Sci
2021
22(1):420
PubMed ID: 33401559
|
16219
Jeongmin Hong, Aya Shiba‐Ishii, Yunjung Kim, Masayuki Noguchi, Noriaki Sakamoto
Ovarian carcinoma immunoreactive antigen domain 2 controls mitochondrial apoptosis in lung adenocarcinoma
Cancer Sci
2021
112(12):5114-5126
PubMed ID: 34628698
|
16225
M Sato, K Hirose, K Ichise, H Yoshino, T Harada, Y Hatayama, H Kawaguchi, M Tanaka, I Fujioka, Y Takai, M Aoki
Not Only Hypoxia- but Radiation-Induced Epithelial-Mesenchymal Transition Is Modulated by Hypoxia-Inducible Factor 1 in A549 Lung Cancer Cells
Folia Biol (Praha)
2021
67(2):62-69.
PubMed ID: 34624938
|
16231
Onuma S, Manabe A, Yoshino Y, Matsunaga T, Asai T, Ikari A.
Upregulation of Chemoresistance by Mg 2+ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells
Cells
2021
10(5):1179
PubMed ID: 34066059
|
16523
Takeru Yamazaki, Kohe Arima, Riku Kubota, Kiyoshi Sato, Hiroyoshi Kawakami
Preparation of Mitochondria‐ and Epigenetics‐Targeting Nanoparticles for Suppression of Cancer Metastasis
Particle & Particle Systems Characterization
2021
38:2100003
|
6923
Nasako H, Akizuki R, Takashina Y, Ishikawa Y, Shinoda T, Shirouzu M, Asai T, Matsunaga T, Endo S, Ikari A.
Claudin-2 binding peptides, VPDSM and DSMKF, down-regulate claudin-2 expression and anticancer resistance in human lung adenocarcinoma A549 cells.
Biochim Biophys Acta Mol Cell Res.
2020
1867(4):118642
PubMed ID: 31923533
|
9729
Yasuhiro Takenouchi, Keisuke Kitakaze, Kazuhito Tsuboi, Yasuo Okamoto
Growth Differentiation Factor 15 Facilitates Lung Fibrosis by Activating Macrophages and Fibroblasts
Exp Cell Res
2020
391(2):112010
PubMed ID: 32305327
|
9819
Keisuke Toda, Mai Ueyama, Shomu Tanaka, Izumi Tsukayama, Takuto Mega, Yuka Konoike, Asako Tamenobu, Februadi Bastian, Iria Akai, Hideyuki Ito, Yuki Kawakami, Yoshitaka Takahashi, Toshiko Suzuki-Yamamoto
Ellagitannins From Punica granatum Leaves Suppress Microsomal Prostaglandin E synthase-1 Expression and Induce Lung Cancer Cells to Undergo Apoptosis
Biosci Biotechnol Biochem
2020
84(4):757-763
PubMed ID: 31868102
|
11986
Maezawa H, Indo HP, Usami N, Majima HJ, Ito H, Ohnishi K, Kobayashi K.
Enhancement of membrane lipid peroxidation in lung cancer cells irradiated with monoenergetic X-rays at the K-shell resonance absorption peak of phosphorus.
J. Radiat. Res.
2020
61(2):237-242.
PubMed ID: 31904079
|
12065
Tomizawa S, Tamori M, Tanaka A, Utsumi N, Sato H, Hatakeyama H, Hisaka A, Kohama T, Yamagata K, Honda T, Nakamura H, Murayama T.
Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.
Biochim Biophys Acta Mol Cell Biol Lipids
2020
PubMed ID: 32112978
|
12375
Morita S, Horii T, Kimura M, Hatada I.
Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9-SunTag Platform
Int J Mol Sci
2020
21(5):1574
PubMed ID: 32106616
|
12376
Uddin M, Kawami M, Yumoto R, Takano M.
Effect of transforming growth factor-β1 on functional expression of monocarboxylate transporter 1 in alveolar epithelial A549 cells
Naunyn Schmiedebergs Arch Pharmacol
2020
393(5):889-896
PubMed ID: 31900520
|
12607
Dukaew N, Konishi T, Chairatvit K, Autsavapromporn N, Soonthornchareonnon N, Wongnoppavich A.
Enhancement of Radiosensitivity by Eurycomalactone in Human NSCLC Cells Through G₂/M Cell Cycle Arrest and Delayed DNA Double-Strand Break Repair
Oncol Res
2020
28(2):161-175
PubMed ID: 31727206
|
12989
Endo M, Ohba K, Sato S, Yokota Y, Takahashi K.
Increased soluble (pro)renin receptor protein by autophagy inhibition in cultured cancer cells.
Genes Cells
2020
PubMed ID: 32314441
|
12990
Eguchi H, Matsunaga T, Endo S, Ichihara K, Ikari A.
Kaempferide Enhances Chemosensitivity of Human Lung Adenocarcinoma A549 Cells Mediated by the Decrease in Phosphorylation of Akt and Claudin-2 Expression.
Nutrients
2020
PubMed ID: 32340376
|
12998
Matsumoto Y, Hattori K, Arima H, Motoyama K, Higashi T, Ishikawa H, Fukumitsu N, Aihara T, Nakai K, Kumada H, Sakurai H.
Folate-appended cyclodextrin improves the intratumoral accumulation of existing boron compounds.
Appl Radiat Isot
2020
PubMed ID: 32561042
|
13002
Ihara H, Mitsuishi Y, Kato M, Takahashi F, Tajima K, Hayashi T, Hidayat M, Winardi W, Wirawan A, Hayakawa D, Kanamori K, Matsumoto N, Yae T, Sato T, Sasaki S, Takamochi K, Suehara Y, Ogura D, Niwa SI, Suzuki K, Takahashi K.
Nintedanib inhibits epithelial-mesenchymal transition in A549 alveolar epithelial cells through regulation of the TGF-β/Smad pathway.
Respir Investig
2020
PubMed ID: 32359980
|
13021
Kurita H, Haruta N, Uchihashi Y, Seto T, Takashima K.
Strand breaks and chemical modification of intracellular DNA induced by cold atmospheric pressure plasma irradiation.
PLoS One
2020
PubMed ID: 32374749
|
13089
Ahmed S, Kobayashi H, Afroz T, Ma N, Oikawa S, Kawanishi S, Murata M, Hiraku Y.
Nitrative DNA damage in lung epithelial cells exposed to indium nanoparticles and indium ions.
Sci Rep
2020
PubMed ID: 32612147
|
13167
Kikuchi N, Soga T, Nomura M, Sato T, Sakamoto Y, Tanaka R, Abe J, Morita M, Shima H, Okada Y, Tanuma N.
Comparison of the ischemic and non-ischemic lung cancer metabolome reveals hyper activity of the TCA cycle and autophagy.
Biochem Biophys Res Commun
2020
PubMed ID: 32828300
|
13228
Togami K, Maruta Y, Nanbu M, Tada H, Chono S.
Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycin-induced pulmonary fibrosis.
Drug Dev Ind Pharm
2020
PubMed ID: 32940095
|
13260
Inoue Y, Okamoto T, Honda T, Nukui Y, Akashi T, Takemura T, Tozuka M, Miyazaki Y.
Disruption in the balance between apolipoprotein A-I and mast cell chymase in chronic hypersensitivity pneumonitis.
Immun Inflamm Dis
2020
PubMed ID: 33016012
|
13295
Doi T, Ogawa H, Tanaka Y, Hayashi Y, Maniwa Y.
Bex1 significantly contributes to the proliferation and invasiveness of malignant tumor cells.
Oncol Lett
2020
PubMed ID: 33133262
|
13342
Chinnathambi S, Hanagata N, Yamazaki T, Shirahata N.
Nano-Bio Interaction between Blood Plasma Proteins and Water-Soluble Silicon Quantum Dots with Enabled Cellular Uptake and Minimal Cytotoxicity.
Nanomaterials (Basel)
2020
PubMed ID: 33202926
|
13432
Kenta Shinha, Wataru Nihei, Tatsuto Ono, Ryota Nakazato, Hiroshi Kimura
A pharmacokinetic–pharmacodynamic model based on multi-organ-on-a-chip for drug–drug interaction studies
Biomicrofluidics
2020
|
13523
Hitomi Fujisaki, Sugiko Futaki, Masashi Yamada, Kiyotoshi Sekiguchi, Toshihiko Hayashi, Shunji Hattori
Adhesion to type I collagen fibrous gels induces E- to N-cadherin switching without other EMT-related phenotypes in lung carcinoma cell A549
bioRxiv
2020
October 04
|
13535
RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells
RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells
DNA Repair (Amst)
2020
91-92:102872
PubMed ID: 32502756
|
13568
Kenta Shinha, Tatsuto Ono, Ryota Nakazato, Hiroshi Kimura
Combination of a multi-organ microphysiological system (MO–MPS) and a pharmacokinetic-pharmacodynamic (PK–PD) model to evaluate drug–drug interactions (DDI)
Authorea Preprints
2020
|
13622
Sato Y, Yoshino H, Tsuruga E, Kashiwakura I.
Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-like Receptor Agonist and Radiation
Curr Cancer Drug Targets
2020
20(5):372-381
PubMed ID: 31951181
|
13767
Togami K, Yamaguchi K, Tada H, Chono S.
Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis
Pharmazie
2020
75(8):371-374
PubMed ID: 32758335
|
13841
Eguchi R, Wakabayashi I.
HDGF enhances VEGF‑dependent angiogenesis and FGF‑2 is a VEGF‑independent angiogenic factor in non‑small cell lung cancer
Oncol Rep
2020
44(1):14-28
PubMed ID: 32319650
|
14832
Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y.
Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines
Arch Virol
2020
165(1):207-214
PubMed ID: 31776677
|
14836
Punzalan LL, Jiang L, Mao D, Mahapatra AD, Sato S, Takemoto Y, Tsujimura M, Kusamori K, Nishikawa M, Zhou L, Uesugi M.
Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library
Cell Chem Biol
2020
27(6):708-718.e1
PubMed ID: 32402240
|
14849
Chikuma K, Arima K, Asaba Y, Kubota R, Asayama S, Sato K, Kawakami H.
The potential of lipid-polymer nanoparticles as epigenetic and ROS control approaches for COPD
Free Radic Res
2020
54(11-12):829-840
PubMed ID: 31809610
|
11371
Aki T, Unuma K, Noritake K, Hirayama N, Funakoshi T, Uemura K.
Formation of high molecular weight p62 by CORM-3.
PLoS ONE
2019
PubMed ID: 30620762
|
4061
Kobayashi A, Autsavapromporn N, Ahmad TAFT, Oikawa M, Homma-Takeda S, Furusawa Y, Wang J, Konishi T.
BYSTANDER WI-38 CELLS MODULATE DNA DOUBLE-STRAND BREAK REPAIR IN MICROBEAM-TARGETED A549 CELLS THROUGH GAP JUNCTION INTERCELLULAR COMMUNICATION.
Radiat Prot Dosimetry
2019
PubMed ID: 30535060
|
4759
Halil I. Ciftci, Mohamed O. Radwan, Safiye E. Ozturk, N. Gokce Ulusoy, Ece Sozer, Doha E. Ellakwa, Zeynep Ocak, Mustafa Can, Taha F.S. Ali, Howaida I. Abd-Alla, Nurettin Yayli, Hiroshi Tateishi, Masami Otsuka and Mikako Fujita
Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity
Molecules
2019
24:3535
PubMed ID: 31574910
|
5357
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
2019
76(5):797-810
PubMed ID: 31606272
|
11634
Autsavapromporn N, Liu C, Kobayashi A, Ahmad TAFT, Oikawa M, Dukaew N, Wang J, Wongnoppavichb A, Konishic T.
Emerging Role of Secondary Bystander Effects Induced by Fractionated Proton Microbeam Radiation.
Radiat. Res.
2019
PubMed ID: 30526323
|
11675
Dr. Ze Yuan, Prof. Toshihiro Nakamura, Dr. Shanmugavel Chinnathambi, Prof. Yanbai Pu, Prof. Naoto Shirahata, Prof. Kiyoto Matsuishi
Facile Formation of Stable Water‐Dispersed Luminescent Silicon Nanocrystals by Laser Processing in Liquid: Toward Fluorescent Labeling for Bio‐Imaging
CHEMNANOMAT
2019
|
11808
Sanomachi T, Suzuki S, Togashi K, Seino S, Yoshioka T, Kitanaka C, Okada M, Yamamoto M.
Brexpiprazole Reduces Survivin and Reverses EGFR Tyrosine Kinase Inhibitor Resistance in Lung and Pancreatic Cancer.
Anticancer Res.
2019
PubMed ID: 31519584
|
11848
Sanomachi T, Suzuki S, Togashi K, Sugai A, Seino S, Okada M, Yoshioka T, Kitanaka C, Yamamoto M.
Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs.
Cancers (Basel)
2019
PubMed ID: 31614999
|
11864
Matsumoto Y, Kuriki H, Kitamura T, Takahashi D, Toshima K.
Total Synthesis and Structure-Activity Relationship Study of Vineomycin A1.
J. Org. Chem.
2019
PubMed ID: 31642324
|
9758
Hiromasa Fujita, Katsumi Hirose, Mariko Sato, Ichitaro Fujioka, Tamaki Fujita, Masahiko Aoki, Yoshihiro Takai
Metformin Attenuates Hypoxia-Induced Resistance to Cisplatin in the HepG2 Cell Line
Oncol Lett
2019
17(2):2431-2440
PubMed ID: 30719114
|
10357
Belgin Sever, Mehlika Dilek Altıntop, Mohamed O Radwan, Ahmet Özdemir, Masami Otsuka, Mikako Fujita, Halil I Ciftci
Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
Eur J Med Chem
2019
82:111648
PubMed ID: 31493743
|
12378
Shirai YT, Mizutani A, Nishijima S, Horie M, Kikuguchi C, Elisseeva O, Yamamoto T.
CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development
Oncogene
2019
38(14):2580-2594
PubMed ID: 30531840
|
12379
Shiba-Ishii A, Hong J, Hirokawa T, Kim Y, Nakagawa T, Sakashita S, Sakamoto N, Kozuma Y, Sato Y, Noguchi M.
Stratifin Inhibits SCF FBW7 Formation and Blocks Ubiquitination of Oncoproteins during the Course of Lung Adenocarcinogenesis
Clin Cancer Res
2019
25(9):2809-2820
PubMed ID: 30728155
|
12380
Chinnathambi S, Hanagata N.
Photostability of quantum dot micelles under ultraviolet irradiation
Luminescence
2019
34(5):472-479
PubMed ID: 30809921
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12381
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Photodiagnosis Photodyn Ther
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Detection of circulating tumor cells with a novel microfluidic system in malignant pleural mesothelioma
Cancer Sci
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BMC Cancer
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Micropassage-embedding composite hydrogel fibers enable quantitative evaluation of cancer cell invasion under 3D coculture conditions.
Lab Chip
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Effects of cationic liposomes with stearylamine against virus infection.
Int J Pharm
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Sasaki M, Anindita PD, Ito N, Sugiyama M, Carr M, Fukuhara H, Ose T, Maenaka K, Takada A, Hall WW, Orba Y, Sawa H
The Role of Heparan Sulfate Proteoglycans as an Attachment Factor for Rabies Virus Entry and Infection.
J Infect Dis
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Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
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Damage-less Handling of Exosomes Using an Ion-depletion Zone in a Microchannel.
Anal Sci
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Integr Mol Med
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Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assay.
Virus Res
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Cytotechnology
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Dasatinib Suppresses TGFβ-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Inhibits Pulmonary Fibrosis.
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Involvement of caspase‑8 in apoptosis enhancement by cotreatment with retinoic acid‑inducible gene‑I‑like receptor agonist and ionizing radiation in human non‑small cell lung cancer.
Mol Med Rep
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CD44v-dependent upregulation of xCT is involved in the acquisition of cisplatin-resistance in human lung cancer A549 cells.
Biochem. Biophys. Res. Commun.
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Potential Role of ASC, a Proapoptotic Protein, for Determining the Cisplatin Susceptibility of Lung Cancer Cells.
Tohoku J. Exp. Med.
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Hayashi Y, Higashi T, Motoyama K, Jono H, Ando Y, Arima H.
In vitro and in vivo siRNA delivery to hepatocyte utilizing ternary complexation of lactosylated dendrimer/cyclodextrin conjugates, siRNA and low-molecular-weight sacran.
Int. J. Biol. Macromol.
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Morimoto Y, Kishida T, Kotani SI, Takayama K, Mazda O.
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Biochem. Biophys. Res. Commun.
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Sakashita M, Sakashita S, Murata Y, Shiba-Ishii A, Kim Y, Matsuoka R, Nakano N, Sato Y, Noguchi M.
High expression of ovarian cancer immunoreactive antigen domain containing 2 (OCIAD2) is associated with poor prognosis in lung adenocarcinoma.
Pathol. Int.
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Suzuki S, Okada M, Takeda H, Kuramoto K, Sanomachi T, Togashi K, Seino S, Yamamoto M, Yoshioka T, Kitanaka C.
Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells.
Oncotarget
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Sasaki K, Miyashita Y, Asai D, Funamoto D, Sato K, Yamaguchi Y, Mishima Y, Iino T, Takaishi S, Nagano J, Kishimura A, Mori T, Katayama Y.
A peptide inhibitor of antibody-dependent cell-mediated cytotoxicity against EGFR/folate receptor-α double positive cells.
Medchemcomm
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Kajiura K, Masuda K, Naruto T, Kohmoto T, Watabnabe M, Tsuboi M, Takizawa H, Kondo K, Tangoku A, Imoto I.
Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.
Oncotarget
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Chem. Biodivers.
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Kobayashi A, Tengku Ahmad TAF, Autsavapromporn N, Oikawa M, Homma-Takeda S, Furusawa Y, Wang J, Konishi T.
Enhanced DNA double-strand break repair of microbeam targeted A549 lung carcinoma cells by adjacent WI38 normal lung fibroblast cells via bi-directional signaling.
Mutat. Res.
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Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin
RSC Adv
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Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata
Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
2017
818, 7-16
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Haruhiko Fuwa, Mizuho Sato
A Synthetic Analogue of Neopeltolide, 8,9-Dehydroneopeltolide, Is a Potent Anti-Austerity Agent Against Starved Tumor Cells
Mar Drugs
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Michinori Takashina, Sayaka Inoue, Kei Tomihara, Kengo Tomita, Kohshi Hattori, Qing-Li Zhao, Tokiko Suzuki, Makoto Noguchi, Wakana Ohashi, Yuichi Hattori
Different Effect of Resveratrol to Induction of Apoptosis Depending on the Type of Human Cancer Cells
Int J Oncol
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Cancer Lett
Lipophilic triphenylphosphonium derivatives enhance radiation-induced cell killing via inhibition of mitochondrial energy metabolism in tumor cells
2017
390:160-167
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Kohei Togami, Kotaro Yamaguchi, Sumio Chono, Hitoshi Tada
Evaluation of permeability alteration and epithelial-mesenchymal transition induced by transforming growth factor-β 1 in A549, NCI-H441, and Calu-3 cells: Development of an in vitro model of respiratory epithelial cells in idiopathic pulmonary fibrosis
J Pharmacol Toxicol Methods
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Anticancer effects of novel thalidomide analogs in A549 cells through inhibition of vascular endothelial growth factor and matrix metalloproteinase-2
Biomed Pharmacother
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85:549-555
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Yokota M, Tamachi T, Yokoyama Y, Maezawa Y, Takatori H, Suto A, Suzuki K, Hirose K, Takeda K, Nakajima H.
IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models
Allergy
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miR-3941: A novel microRNA that controls IGBP1 expression and is associated with malignant progression of lung adenocarcinoma
Cancer Sci
2017
108(3):536-542
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Sunada S, Hirakawa H, Fujimori A, Uesaka M, Okayasu R.
Oxygen Enhancement Ratio in Radiation-Induced Initial DSBs by an Optimized Flow Cytometry-based Gamma-H2AX Analysis in A549 Human Cancer Cells
Radiat Res
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188(5):591-594
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Takahashi K, Ohta T.
Membrane translocation of transient receptor potential ankyrin 1 induced by inflammatory cytokines in lung cancer cells
Biochem Biophys Res Commun
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Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy
J Am Chem Soc
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Olanzapine, an Atypical Antipsychotic, Inhibits Survivin Expression and Sensitizes Cancer Cells to Chemotherapeutic Agents
Anticancer Res
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37(11):6177-6188
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Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I.
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Nat. Biotechnol.
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Multicomponent Coculture System of Cancer Cells and Two Types of Stromal Cells for In Vitro Evaluation of Anticancer Drugs.
Tissue Eng Part C Methods
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Shimobaba S, Taga S, Akizuki R, Hichino A, Endo S, Matsunaga T, Watanabe R, Yamaguchi M, Yamazaki Y, Sugatani J, Ikari A.
Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.
Biochim. Biophys. Acta
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Nagashima S, Kobayashi T, Tanaka T, Tanggis , Jirintai S, Takahashi M, Nishizawa T, Okamoto H.
Analysis of adaptive mutations selected during the consecutive passages of hepatitis E virus produced from an infectious cDNA clone.
Virus Res.
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Watarai H, Okada M, Kuramoto K, Takeda H, Sakaki H, Suzuki S, Seino S, Oizumi H, Sadahiro M, Kitanaka C.
Impact of H3K27 Demethylase Inhibitor GSKJ4 on NSCLC Cells Alone and in Combination with Metformin.
Anticancer Res.
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Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masaya Takehara, Masahiro Nagahama
Clostridium Perfringens Delta-Toxin Induces Rapid Cell Necrosis
PLoS One
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11 (1), e0147957
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Takahiro Nomoto, Shigeto Fukushima, Michiaki Kumagai, Kozo Miyazaki, Aki Inoue, Peng Mi, Yoshinori Maeda, Kazuko Toh, Yu Matsumoto, Yuji Morimoto, Akihiro Kishimura, Nobuhiro Nishiyama, Kazunori Kataoka
Calcium Phosphate-Based Organic-Inorganic Hybrid Nanocarriers With pH-responsive on/Off Switch for Photodynamic Therapy
Biomater Sci .
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Tabei Y, Sonoda A, Nakajima Y, Biju V, Makita Y, Yoshida Y, Horie M.
Intracellular accumulation of indium ions released from nanoparticles induces oxidative stress, proinflammatory response and DNA damage
J Biochem
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159(2):225-37
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Takeda H, Okada M, Suzuki S, Kuramoto K, Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T, Kitanaka C.
Rho-Associated Protein Kinase (ROCK) Inhibitors Inhibit Survivin Expression and Sensitize Pancreatic Cancer Stem Cells to Gemcitabine
Anticancer Res
2016
36(12):6311-6318
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Okada M, Kuramoto K, Takeda H, Watarai H, Sakaki H, Seino S, Seino M, Suzuki S, Kitanaka C.
The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo
Oncotarget
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Hino H, Kamiya M, Kitano K, Mizuno K, Tanaka S, Nishiyama N, Kataoka K, Urano Y, Nakajima J.
Rapid Cancer Fluorescence Imaging Using A γ-Glutamyltranspeptidase-Specific Probe For Primary Lung Cancer
Transl Oncol
2016
9(3):203-10
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Husni RE, Shiba-Ishii A, Iiyama S, Shiozawa T, Kim Y, Nakagawa T, Sato T, Kano J, Minami Y, Noguchi M.
DNMT3a expression pattern and its prognostic value in lung adenocarcinoma
Lung Cancer
2016
97:59-65
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Toyama K, Mizuguchi T, Nomura W, Tamamura H.
Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization
Bioorg Med Chem
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24(16):3406-12
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Ali F, Yamaguchi K, Fukuoka M, Elhelaly AE, Kuwata K.
Logical design of an anti-cancer agent targeting the plant homeodomain in Pygopus2
Cancer Sci
2016
107(9):1321-8
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Fukushi S, Yoshino H, Yoshizawa A, Kashiwakura I.
p53-independent structure-activity relationships of 3-ring mesogenic compounds' activity as cytotoxic effects against human non-small cell lung cancer lines
BMC Cancer
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16:521
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Hiraku Y, Guo F, Ma N, Yamada T, Wang S, Kawanishi S, Murata M.
Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation
Part Fibre Toxicol
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Tanabe K.
Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization
Sci Rep
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6:25095
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Sunada S, Kanai H, Lee Y, Yasuda T, Hirakawa H, Liu C, Fujimori A, Uesaka M, Okayasu R.
Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair
Cancer Sci
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107(9):1250-5
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Rana U, Chakraborty C, Pandey RK, Hossain MD, Nagano R, Morita H, Hattori S, Minowa T, Higuchi M.
Selective DNA Recognition and Cytotoxicity of Water-Soluble Helical Metallosupramolecular Polymers
Bioconjug Chem
2016
27(10):2307-2314
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Suzuki S, Okada M, Kuramoto K, Takeda H, Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T, Kitanaka C.
Aripiprazole, an Antipsychotic and Partial Dopamine Agonist, Inhibits Cancer Stem Cells and Reverses Chemoresistance
Anticancer Res
2016
36(10):5153-5161
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Maeda K, Yasui H, Yamamori T, Matsuura T, Takao S, Suzuki M, Matsuda A, Inanami O, Shirato H.
A Nucleoside Anticancer Drug, 1-(3-C-Ethynyl-β-D-Ribo-Pentofuranosyl)Cytosine, Induces Depth-Dependent Enhancement of Tumor Cell Death in Spread-Out Bragg Peak (SOBP) of Proton Beam
PLoS One
2016
11(11):e0166848
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Zhang J, Yamada S, Ogihara E, Kurita M, Banno N, Qu W, Feng F, Akihisa T.
Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark
Chem Biodivers
2016
13(11):1601-1609
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Nozomu Kiyama, Shigeaki Abe, Shuichi Yamagata, Yasuhiro Yoshida, Junichiro Iida
Evaluation of the Biocompatibility of Ceramic Nanoparticles with A549 Lung Epithelial Cells
Nanoscience and Nanotechnology Letters
2016
8:310-315
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Tabata A, Ohkubo Y, Anyoji N, Hojo K, Tomoyasu T, Tatematsu Y, Ohkura K, Nagamune H.
Development of a Sortase A-mediated Peptide-labeled Liposome Applicable to Drug-delivery Systems.
Anticancer Res
2015
35(8):4411-7
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Katono K, Sato Y, Jiang SX, Kobayashi M, Nagashio R, Ryuge S, Fukuda E, Goshima N, Satoh Y, Saegusa M, Masuda N.
Prognostic significance of MYH9 expression in resected non-small cell lung cancer
PLoS One
2015
10(3):e0121460
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Hosokawa Y, Monzen S, Yoshino H, Terashima S, Nakano M, Toshima K, Saga R, Kashiwakura I.
Effects of X‑ray irradiation in combination with ascorbic acid on tumor control
Mol Med Rep
2015
12(4):5449-54
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Yoshimasu T, Ohashi T, Oura S, Kokawa Y, Kawago M, Hirai Y, Miyasaka M, Nishiguchi H, Kawashima S, Yata Y, Honda M, Fujimoto T, Okamura Y.
A Theoretical Model for the Hormetic Dose-response Curve for Anticancer Agents
Anticancer Res
2015
35(11):5851-5
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Okada K, Chikumi H, Takata M, Yamaguchi K, Makino H, Kitaura T, Nakamoto M, Yamasaki A, Igishi T, Burioka N, Shimizu E.
Effect of Clarithromycin on the Expression of UL16-Binding Protein 2 in Human Cells
Yonago Acta Med
2015
58(1):31-8
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Zhang J, Kurita M, Ebina K, Ukiya M, Tokuda H, Yasukawa K, Masters ET, Shimizu N, Akihisa M, Feng F, Akihisa T.
Melanogenesis-inhibitory activity and cancer chemopreventive effect of glucosylcucurbic acid from shea (Vitellaria paradoxa) kernels
Chem Biodivers
2015
12(4):547-58
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Sugano T, Seike M, Noro R, Soeno C, Chiba M, Zou F, Nakamichi S, Nishijima N, Matsumoto M, Miyanaga A, Kubota K, Gemma A.
Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer
Mol Cancer Ther
2015
14(11):2433-40
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Pauli G, Aepfelbacher M, Bauerfeind U, Blümel J, Burger R, Gärtner B, Gröner A, Gürtler L, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Schlenkrich U, Schottstedt V, Seitz R, Strobel J, Willkommen H, Baylis SA, German Advisory Committee Blood (Arbeitskreis Blut), Subgroup ‘Assessment of Pathogens Transmissible by Blood’.
Hepatitis E Virus
Transfus Med Hemother
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2(4):247-65.
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Tabei Y, Sonoda A, Nakajima Y, Biju V, Makita Y, Yoshida Y, Horie M.
In vitro evaluation of the cellular effect of indium tin oxide nanoparticles using the human lung adenocarcinoma A549 cells
Metallomics
2015
7(5):816-27
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Nagashima S, Jirintai S, Takahashi M, Kobayashi T, Tanggis, Nishizawa T, Kouki T, Yashiro T, Okamoto H.
Hepatitis E virus egress depends on the exosomal pathway, with secretory exosomes derived from multivesicular bodies.
J Gen Virol
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Narita K, Matsuda Y, Seike M, Naito Z, Gemma A, Ishiwata T.
Nestin regulates proliferation, migration, invasion and stemness of lung adenocarcinoma
Int J Oncol
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44(4):1118-30
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Kitamura K, Seike M, Okano T, Matsuda K, Miyanaga A, Mizutani H, Noro R, Minegishi Y, Kubota K, Gemma A.
MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells
Mol Cancer Ther
2014
13(2):444-53
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Pan X, Matsumoto M, Nakamura Y, Kikuchi T, Zhang J, Ukiya M, Suzuki T, Koike K, Akihisa R, Akihisa T.
Three new and other limonoids from the hexane extract of Melia azedarach fruits and their cytotoxic activities
Chem Biodivers
2014
11(7):987-1000
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Kitdamrongtham W, Ishii K, Ebina K, Zhang J, Ukiya M, Koike K, Akazawa H, Manosroi A, Manosroi J, Akihisa T.
Limonoids and flavonoids from the flowers of Azadirachta indica var. siamensis, and their melanogenesis-inhibitory and cytotoxic activities
Chem Biodivers
2014
11(1):73-84
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Kazuhiro Hiyama, Hirofumi Matsui, Masato Tamura, Osamu Shimokawa, Mariko Hiyama, Tsuyoshi Kaneko, Yumiko Nagano, Ichinosuke Hyodo, Junko Tanaka, Yoshihiro Miwa, Tetsuo Ogawa, Takeo Nakanishi and Ikumi Tamai
Cancer cells uptake porphyrins via heme carrier protein 1
Journal of Porphyrins and Phthalocyanines
2013
17:36-43
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Masayasu Mie, Mayu Oomuro, Eiry Kobatake
Hydrogel scaffolds composed of genetically synthesized self-assembling peptides for three-dimensional cell culture
Polymer Journal
2013
45:504-508
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Fujitani N, Furukawa J, Araki K, Fujioka T, Takegawa Y, Piao J, Nishioka T, Tamura T, Nikaido T, Ito M, Nakamura Y, Shinohara Y.
Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers
Proc Natl Acad Sci U S A
2013
110(6):2105-10
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Ukiya M, Sawada S, Kikuchi T, Kushi Y, Fukatsu M, Akihisa T.
Cytotoxic and apoptosis-inducing activities of steviol and isosteviol derivatives against human cancer cell lines
Chem Biodivers
2013
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