| 利用者成果(英) |
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17602
Someya Y, Kobayashi S, Toriumi K, Takeda S, Adachi N, Kurosawa A.
A Cell System-Assisted Strategy for Evaluating the Natural Antioxidant-Induced Double-Stranded DNA Break (DSB) Style
Genes (Basel)
2023
14(2):420
PubMed ID: 36833347
DOI: 10.3390/genes14020420
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17619
Ebata H, Umeda K, Nishizawa K, Nagao W, Inokuchi S, Sugino Y, Miyamoto T, Mizuno D.
Activity-dependent glassy cell mechanics Ⅰ: Mechanical properties measured with active microrheology
Biophys J
2023
;S0006-3495(23)00241-2
PubMed ID: 37050875
DOI: 10.1016/j.bpj.2023.04.011
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17786
Nakagawa Y, Hishida T, Sumaru K, Morishita K, Kirito K, Yokojima S, Sakamoto Y, Nakamura S, Uchida K.
Phototunable Cell Killing by Photochromic Diarylethene of Thiazoyl and Thienyl Derivatives
J Med Chem
2023
;66(8):5937-5949
PubMed ID: 37128763
DOI: 10.1021/acs.jmedchem.3c00164
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17799
Zhu Z, Kitano T, Morimatsu M, Ochiai K, Ishiguro-Oonuma T, Oosumi K, Lin X, Orino K, Yoshikawa Y.
A Highly Conserved Region in BRCA2 Suppresses the RAD51-Interaction Activity of BRC Repeats
Vet Sci
2023
10(2):145
PubMed ID: 36851449
DOI: 10.3390/vetsci10020145
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17801
Ryo Kobori, Ryo Doge, Momoka Takae, Atoru Aoki, Takashi Kawasaki, Akiko Saito
Potential of Raspberry Flower Petals as a Rich Source of Bioactive Flavan-3-ol Derivatives Revealed by Polyphenolic Profiling
Nutraceuticals
2023
3:196-209
DOI: 10.3390/nutraceuticals3020015
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17804
Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, and Hiroyuki Kawahara
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases
iScience
2023
DOI: 10.1016/ j.isci.2023.106652
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20972
Tojima T, Miyashiro D, Kosugi Y, Nakano A.
Super-Resolution Live Imaging of Cargo Traffic Through the Golgi Apparatus in Mammalian Cells.
Methods Mol Biol
2023
2557:127-140
PubMed ID: 36512214
DOI: 10.1007/978-1-0716-2639-9_10
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20990
Wang Y, Suzuki R, Fujii A, Ieki K, Goda W, Yasui M, Abe Y.
A tyrosine-based YXXΦ motif regulates the degradation of aquaporin-4 via both lysosomal and proteasomal pathways and is functionally inhibited by a ten-amino-acid sequence within its C-terminus.
FEBS J
2023
PubMed ID: 36597763
DOI: 10.1111/febs.16717
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20991
Jin X, Tanaka H, Jin M, Fujita K, Homma H, Inotsume M, Yong H, Umeda K, Kodera N, Ando T, Okazawa H.
PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions.
Nat Commun
2023
14(1):9
PubMed ID: 36599853
DOI: 10.1038/s41467-022-35602-w
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21014
Yamada I, Kataoka T, Ikeda R, Tagaya M.
Investigation into the Photochemical Properties of Methylene Blue-Immobilized Hydroxyapatite Nanoparticles for Theranostic Application.
ACS Appl Bio Mater
2023
PubMed ID: 36648755
DOI: 10.1021/acsabm.2c00756
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21065
Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
J Am Chem Soc
2023
145(1):135-142
PubMed ID: 36538570
DOI: 10.1021/jacs.2c08974
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21072
Onishi K, Ishihara S, Takahashi M, Sakai A, Enomoto A, Suzuki K, Haga H.
Substrate stiffness induces nuclear localization of myosin regulatory light chain to suppress apoptosis.
FEBS Lett
2023
PubMed ID: 36723402
DOI: 10.1002/1873-3468.14592
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21168
Yang J, Liu L, Oda Y, Wada K, Ago M, Matsuda S, Hattori M, Goto T, Kawashima Y, Matsuzaki Y, Taketani T.
Highly-purified rapidly expanding clones, RECs, are superior for functional-mitochondrial transfer.
Stem Cell Res Ther
2023
14(1):40
PubMed ID: 36927781
DOI: 10.1186/s13287-023-03274-y
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21332
Ueda H, Tran QTH, Tran LNT, Higasa K, Ikeda Y, Kondo N, Hashiyada M, Sato C, Sato Y, Ashida A, Nishio S, Iwata Y, Iida H, Matsuoka D, Hidaka Y, Fukui K, Itami S, Kawashita N, Sugimoto K, Nozu K, Hattori M, Tsukaguchi H.
Characterization of cytoskeletal and structural effects of INF2 variants causing glomerulopathy and neuropathy.
Sci Rep
2023
13(1):12003
PubMed ID: 37491439
DOI: 10.1038/s41598-023-38588-7
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21366
Takahashi D, Ora T, Sasaki S, Ishii N, Tanaka T, Matsuda T, Ikeda M, Moriyama J, Cho N, Nara H, Maezaki H, Kamaura M, Shimokawa K, Arimoto H.
Second-Generation AUTACs for Targeted Autophagic Degradation.
J Med Chem
2023
PubMed ID: 37589438
DOI: 10.1021/acs.jmedchem.3c00861
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21373
Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.
TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.
Nat Commun
2023
14(1):4521
PubMed ID: 37607907
DOI: 10.1038/s41467-023-40243-8
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17560
Ueoka R, Sondermann P, Leopold-Messer S, Liu Y, Suo R, Bhushan A, Vadakumchery L, Greczmiel U, Yashiroda Y, Kimura H, Nishimura S, Hoshikawa Y, Yoshida M, Oxenius A, Matsunaga S, Williamson RT, Carreira EM, Piel J.
Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium
Nat Chem
2022
Nat Chem . 2022 Oct;14(10):1193-1201.
PubMed ID: 36064972
DOI: 10.1038/s41557-022-01020-0
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17700
Tan A, Xu F, Yokoyama C, Yano S, Konno H.
Design, synthesis, and evaluation of the self-assembled antimicrobial peptides based on the ovalbumin-derived peptide TK913
J Pept Sci
2022
28(4):e3375
PubMed ID: 34725889
DOI: 10.1002/psc.3375
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17709
Kimura A, Arai T, Ueno M, Oyama K, Yu H, Yamashita S, Otome Y, Taguchi M.
Synthesis of Small Peptide Nanogels Using Radiation Crosslinking as a Platform for Nano-Imaging Agents for Pancreatic Cancer Diagnosis
Pharmaceutics
2022
14(11):2400
PubMed ID: 36365217
DOI: 10.3390/pharmaceutics14112400
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17783
Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N.
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
J Cell Biol
2022
221(10):e202203102
PubMed ID: 36066504
DOI: 10.1083/jcb.202203102
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17788
Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.
First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Commun Biol
2022
5(1):1132
PubMed ID: 36289442
DOI: 10.1038/s42003-022-04110-4
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20504
Suzuki M, Iwaki K, Kikuchi M, Fujiwara K, Doi N.
Characterization of the membrane penetration-enhancing peptide S19 derived from human syncytin-1 for the intracellular delivery of TAT-fused proteins.
Biochem Biophys Res Commun
2022
586:63-67
PubMed ID: 34826702
DOI: 10.1016/j.bbrc.2021.11.065
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20518
Kadota A, Moriguchi M, Watanabe T, Sekine Y, Nakamura S, Yasuno T, Ohe T, Mashino T, Fujimuro M.
A pyridinium‑type fullerene derivative suppresses primary effusion lymphoma cell viability via the downregulation of the Wnt signaling pathway through the destabilization of β‑catenin.
Oncol Rep
2022
47(3)
PubMed ID: 35014678
DOI: 10.3892/or.2022.8257
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16222
Xiaobo Yin, Takayuki Konishi, Kazuo Horikawa, Ryota Tanaka, Yuki Togo, Takanori Noda, Miho Hosoi, Mie Tsuchida, Tatsuki Kunoh, Shuichi Wada, Toshinobu Nakamura, Eisuke Tsuda, Ryuzo Sasaki, Tamio Mizukami, Makoto Hasegawa
Structure and Function of Potential Glycosylation Sites of Dynactin-Associated Protein dynAP
Mol Biotechnol
2022
Jan 13
PubMed ID: 35022995
DOI: 10.1007/s12033-021-00435-3
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16386
Haraguchi T, Koujin T, Shindo T, Bilir Ş, Osakada H, Nishimura K, Hirano Y, Asakawa H, Mori C, Kobayashi S, Okada Y, Chikashige Y, Fukagawa T, Shibata S, Hiraoka Y.
Transfected plasmid DNA is incorporated into the nucleus via nuclear envelope reformation at telophase
Commun Biol
2022
5(1):78
PubMed ID: 35058555
DOI: 10.1038/s42003-022-03021-8
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16391
Sakamoto T, Yu Z, Otani Y.
Dual-Color Fluorescence Switch-On Probe for Imaging G-Quadruplex and Double-Stranded DNA in Living Cells
Anal Chem
2022
Mar 2
PubMed ID: 35234461
DOI: 10.1021/acs.analchem.1c04804
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16428
Fukushima S, Shimohata T, Inoue Y, Kido J, Uebanso T, Mawatari K, Takahashi A.
Recruitment of LC3 by Campylobacter jejuni to Bacterial Invasion Site on Host Cells via the Rac1-Mediated Signaling Pathway
Front Cell Infect Microbiol
2022
12:829682
PubMed ID: 35310852
DOI: 10.3389/fcimb.2022.829682
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20613
Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.
Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.
Analyst
2022
PubMed ID: 35297918
DOI: 10.1039/d2an00052k
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20616
Liu JY, Inoshita T, Shiba-Fukushima K, Yoshida S, Ogata K, Ishihama Y, Imai Y, Hattori N.
Ubiquitination at the lysine 27 residue of the parkin ubiquitin-like domain is suggestive of a new mechanism of parkin activation.
Hum Mol Genet
2022
PubMed ID: 35313349
DOI: 10.1093/hmg/ddac064
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20645
Oda R, Shou J, Zhong W, Ozeki Y, Yasui M, Nuriya M.
Direct visualization of general anesthetic propofol on neurons by stimulated Raman scattering microscopy.
iScience
2022
25(3):103936
PubMed ID: 35252821
DOI: 10.1016/j.isci.2022.103936
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20659
Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.
EMBO Rep
2022
e54801
PubMed ID: 35417087
DOI: 10.15252/embr.202254801
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20669
Nakahata M, Tominaga N, Saito K, Nishiyama K, Tanino Y, Saiki K, Kojima M, Sakai S.
A bio-synthetic hybrid hydrogel formed under physiological conditions consisting of mucin and a synthetic polymer carrying boronic acid.
Macromol Biosci
2022
e2200055
PubMed ID: 35429097
DOI: 10.1002/mabi.202200055
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16520
Nagayama K, Hanzawa T.
Cell type-specific orientation and migration responses for a microgrooved surface with shallow grooves
Biomed Mater Eng
2022
Feb 14
PubMed ID: 35180105
DOI: 10.3233/BME-211356
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20725
Inagaki E, Arai E, Hatou S, Sayano T, Taniguchi H, Negishi K, Kanai Y, Sato Y, Okano H, Tsubota K, Shimmura S.
The Anterior Eye Chamber as a Visible Medium for In Vivo Tumorigenicity Tests.
Stem Cells Transl Med
2022
PubMed ID: 35666752
DOI: 10.1093/stcltm/szac036
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20751
Wada KI, Hosokawa K, Ito Y, Maeda M, Harada Y, Yonemitsu Y.
Generation of transmitochondrial cybrids using a microfluidic device.
Exp Cell Res
2022
418(1):113233
PubMed ID: 35659971
DOI: 10.1016/j.yexcr.2022.113233
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20752
Shindo S, Shioya A, Watanabe M, Sasaki T, Suzuki H, Kumagai T, Hwang GW, Nagata K.
Development of an adenovirus-mediated reporter assay system to detect a low concentration of retinoic acid in MCF-7 cells.
J Toxicol Sci
2022
47(6):249-255
PubMed ID: 35650141
DOI: 10.2131/jts.47.249
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20755
Sonoda K, Bogahawatta S, Katayama A, Ujike S, Kuroki S, Kitagawa N, Hirotsuru K, Suzuki N, Miyata T, Kawaguchi SI, Tsujita T.
Prolyl Hydroxylase Domain Protein Inhibitor Not Harboring a 2-Oxoglutarate Scaffold Protects against Hypoxic Stress.
ACS Pharmacol Transl Sci
2022
5(5):362-372
PubMed ID: 35592438
DOI: 10.1021/acsptsci.2c00002
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16707
Yasuyuki Morita
A Technique for Measuring the 3D Deformation of a Multiphase Structure to Elucidate the Mechanism of Tumor Invasion
Multidisciplinary Computational Anatomy
2022
139-143
DOI: 10.1007/978-981-16-4325-5_16
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16712
Chukai Y, Ito G, Konno M, Sakata Y, Ozaki T.
Mitochondrial calpain-5 truncates caspase-4 during endoplasmic reticulum stress
Biochem Biophys Res Commun
2022
608:156-162
PubMed ID: 35398613
DOI: 10.1016/j.bbrc.2022.03.156
|
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16720
Yoshiro Tahara, Kenichi Ueyama, Michiaki Matsumoto
Glycine-Mediated Paclitaxel Dispersion in a Phospholipid Complex
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN
2022
55:225-229
DOI: 10.1252/jcej.21we113
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16721
Tatsuno T, Ishigaki Y.
Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m 6 A Reader YTHDC1 in Human Cells
Cells
2022
11(9):146
PubMed ID: 35563766
DOI: 10.3390/cells11091461
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16732
Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.
BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents
Int J Mol Sci
2022
23(7):4060
PubMed ID: 35409418
DOI: 10.3390/ijms23074060
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20840
Haraguchi-Suzuki K, Kawabata-Iwakawa R, Suzuki T, Suto T, Takazawa T, Saito S.
Local anesthetic lidocaine-inducible gene, growth differentiation factor-15 suppresses the growth of cancer cell lines.
Sci Rep
2022
12(1):14520
PubMed ID: 36008442
DOI: 10.1038/s41598-022-18572-3
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20894
Kubota F, Satrialdi, Takano Y, Maeki M, Tokeshi M, Harashima H, Yamada Y.
Fine-tuning the encapsulation of a photosensitizer in nanoparticles reveals the relationship between internal structure and phototherapeutic effects.
J Biophotonics
2022
e202200119
PubMed ID: 36054273
DOI: 10.1002/jbio.202200119
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20895
Yoneda Y, Yahagi T, Harada K, Okamoto Y, Motai S, Matsuzaki K, Kubo M, Fukuyama Y, Ohsaki A.
Anchietins A-E: 30-norfriedelane-type triterpenes from Anchietea pyrifolia.
Phytochemistry
2022
203:113388
PubMed ID: 36075316
DOI: 10.1016/j.phytochem.2022.113388
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20917
Debnath T, Hattori R, Okamoto S, Shibata T, Santra TS, Nagai M.
Automated detection of patterned single-cells within hydrogel using deep learning.
Sci Rep
2022
12(1):18343
PubMed ID: 36316380
DOI: 10.1038/s41598-022-22774-0
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20927
Nakamura M, Fujiwara K, Doi N.
Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide.
J Nanobiotechnology
2022
20(1):458
PubMed ID: 36303212
DOI: 10.1186/s12951-022-01667-4
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20954
Ohe S, Kubota Y, Yamaguchi K, Takagi Y, Nashimoto J, Kozuka-Hata H, Oyama M, Furukawa Y, Takekawa M.
ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II.
Nat Commun
2022
13(1):7476
PubMed ID: 36463234
DOI: 10.1038/s41467-022-35230-4
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20955
Morotomi-Yano K, Hiromoto Y, Higaki T, Yano KI.
Disease-associated H58Y mutation affects the nuclear dynamics of human DNA topoisomerase IIβ.
Sci Rep
2022
12(1):20627
PubMed ID: 36450898
DOI: 10.1038/s41598-022-24883-2
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21166
Ogushi S, Kimura T.
The Difference in Zinc Concentrations Required for Induction among Metallothionein Isoforms Can Be Explained by the Different MTF1 Affinities to MREs in Its Promoter.
Int J Mol Sci
2022
24(1)
PubMed ID: 36613726
DOI: 10.3390/ijms24010283
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13251
Saito M.
Fluorescent Labeling of Connexin with As Complex and X-Y Coordinate Registration of Target Single Cells Based on a Triangle Standard Chip for the Image Analysis of Gap Junctional Communication.
Methods Mol Biol
2021
PubMed ID: 32989705
DOI: 10.1007/7651_2020_330
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13328
Kagabu M, Yoshino N, Saito T, Miura Y, Takeshita R, Murakami K, Kawamura H, Baba T, Sugiyama T.
The efficacy of a third-generation oncolytic herpes simplex viral therapy for an HPV-related uterine cervical cancer model.
Int J Clin Oncol
2021
26(3):591-597.
PubMed ID: 33146805
DOI: 10.1007/s10147-020-01823-6
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13367
Yamaguchi K, Otomo K, Kozawa Y, Tsutsumi M, Inose T, Hirai K, Sato S, Nemoto T, Uji-I H.
Adaptive Optical Two-Photon Microscopy for Surface-Profiled Living Biological Specimens.
ACS Omega
2021
PubMed ID: 33458495
DOI: 10.1021/acsomega.0c04888
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20001
Fukuchi M, Oyama K, Mizuno H, Miyagawa A, Koumoto K, Fukuhara G.
Hydrostatic Pressure-Regulated Cellular Calcium Responses.
Langmuir
2021
37(2) 820-826
PubMed ID: 33410684
DOI: 10.1021/acs.langmuir.0c03141
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13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
PubMed ID: 33615198
DOI: 10.1016/j.isci.2021.102090
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20019
Chau S, Fujii A, Wang Y, Vandebroek A, Goda W, Yasui M, Abe Y.
Di-lysine motif-like sequences formed by deleting the C-terminal domain of aquaporin-4 prevent its trafficking to the plasma membrane.
Genes Cells
2021
PubMed ID: 33474763
DOI: 10.1111/gtc.12829
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20040
Nara T, Nakagawa Y, Tsuganezawa K, Yuki H, Sekimata K, Koyama H, Ogawa N, Honma T, Shirouzu M, Fukami T, Matsuo Y, Inaoka DK, Kita K, Tanaka A.
The ubiquinone synthesis pathway is a promising drug target for Chagas disease.
PLoS One
2021
16(2):e0243855
PubMed ID: 33539347
DOI: 10.1371/journal.pone.0243855
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20048
Liu X, Suyama K, Nose T, Shimohigashi M, Shimohigashi Y.
Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding.
PLoS One
2021
16(2):e0246583
PubMed ID: 33561155
DOI: 10.1371/journal.pone.0246583
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20053
Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.
Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.
Pediatr Hematol Oncol
2021
1-16
PubMed ID: 33622161
DOI: 10.1080/08880018.2021.1887984
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20078
Chukai Y, Iwamoto T, Itoh K, Tomita H, Ozaki T.
Characterization of mitochondrial calpain-5.
Biochim Biophys Acta Mol Cell Res
2021
1868(5):118989
PubMed ID: 33607190
DOI: 10.1016/j.bbamcr.2021.118989
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20112
Liu X, Matsuyama Y, Shimohigashi M, Shimohigashi Y.
ERα-agonist and ERβ-antagonist bifunctional next-generation bisphenols with no halogens: BPAP, BPB, and BPZ.
Toxicol Lett
2021
345:24-33
PubMed ID: 33857583
DOI: 10.1016/j.toxlet.2021.04.001
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14002
Vong K, Tahara T, Urano S, Nasibullin I, Tsubokura K, Nakao Y, Kurbangalieva A, Onoe H, Watanabe Y, Tanaka K. タイトル
Disrupting tumor onset and growth via selective cell tagging (SeCT) therapy
Sci Adv
2021
7(17):eabg4038
PubMed ID: 33893089
DOI: 10.1126/sciadv.abg4038
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14183
Okawa F, Hama Y, Zhang S, Morishita H, Yamamoto H, Levine TP, Mizushima N.
Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1
J Cell Sci
2021
134(8):jcs255877
PubMed ID: 33771928
DOI: 10.1242/jcs.255877
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20153
Yin X, Yamada S, Kobayashi H, Tanaka R, Togo Y, Hosoi M, Tsuchida M, Kunoh T, Wada S, Nakamura T, Sasaki R, Mizukami T, Hasegawa M.
Expression and cell transformation activity of dynactin-associated protein isoforms.
FEBS Open Bio
2021
PubMed ID: 34043884
DOI: 10.1002/2211-5463.13202
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20156
Oyama TG, Oyama K, Kimura A, Yoshida F, Ishida R, Yamazaki M, Miyoshi H, Taguchi M.
Collagen hydrogels with controllable combined cues of elasticity and topography to regulate cellular processes.
Biomed Mater
2021
PubMed ID: 34030146
DOI: 10.1088/1748-605X/ac0452
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20003
Inaba H, Miao Q, Nakata T.
Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling
Biol Chem
2021
296:100290
PubMed ID: 33453281
DOI: 10.1016/j.jbc.2021.100290
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14869
Torii C, Maishi N, Kawamoto T, Morimoto M, Akiyama K, Yoshioka Y, Minami T, Tsumita T, Alam MT, Ochiya T, Hida Y, Hida K.
miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells
Sci Rep
2021
11(1):13502
PubMed ID: 34226586
DOI: 10.1038/s41598-021-92879-5
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15011
Sekino Y, Imaizumi A, Komune N, Ono M, Sato K, Masuda S, Fujimura A, Koike K, Hongo T, Uchi R, Onishi H, Nakagawa T.
Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma
FEBS Open Bio
2021
Jun 11
PubMed ID: 34115931
DOI: 10.1002/2211-5463.13225
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20253
Yanagi T, Kaminaga K, Suzuki M, Abe H, Yamamoto H, Ohshima T, Kuwahata A, Sekino M, Imaoka T, Kakinuma S, Sugi T, Kada W, Hanaizumi O, Igarashi R.
All-Optical Wide-Field Selective Imaging of Fluorescent Nanodiamonds in Cells, In Vivo and Ex Vivo.
ACS Nano
2021
PubMed ID: 34339180
DOI: 10.1021/acsnano.0c07740
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20290
Kimura A, Ueno M, Arai T, Oyama K, Taguchi M.
Radiation Crosslinked Smart Peptide Nanoparticles: A New Platform for Tumor Imaging.
Nanomaterials (Basel)
2021
11(3)
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Protocol for synthesis and use of a turn-on fluorescent probe for quantifying labile Zn2+ in the Golgi apparatus in live cells.
STAR Protoc
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Ternary Complexes of pDNA, Neuron-Binding Peptide, and PEGylated Polyethyleneimine for Brain Delivery with Nano-Bubbles and Ultrasound.
Pharmaceutics
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DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency
Nat Commun
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Tomoko Gowa Oyama, Kotaro Oyama, Hiromi Miyoshi, Mitsumasa Taguchi
3D cell sheets formed via cell-driven buckling-delamination of patterned thin films
Materials & Design
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2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition.
Sci Rep
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Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms.
J Cell Sci
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A novel endoplasmic stress mediator, Kelch domain containing 7B (KLHDC7B), increased Harakiri (HRK) in the SubAB-induced apoptosis signaling pathway.
Cell Death Discov
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Constitutive activation of S1P receptors at the trans-Golgi network is required for surface transport carrier formation.
iScience
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Sawa C, Yofu S, Kiriyama K, Sutoh K, Saito T, Kishi S, Gunji M, Inoue Y, Sugi M, Shioda S, Honda K.
High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.
Heliyon
2021
7(11):e08318
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Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display
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Tsuzuki H, Nagatsuka Y, Iwata M, Kitamura N, Nagasawa Y, Matsumoto T, Ito R, Takahashi T, Ito M, Nakamura H, Takei M.
Antinuclear antibodies produced in HLA-DR transgenic humanized mice developed chronic graft-versus-host disease.
Heliyon
2021
7(11):e08380
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Hepatocyte-Specific Co-Delivery of Zinc Ions and Plasmid DNA by Lactosylated Poly(1-vinylimidazole) for Suppression of Insulin Receptor Internalization
Pharmaceutics
2021
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Arung ET, Ramadhan R, Khairunnisa B, Amen Y, Matsumoto M, Nagata M, Kusuma IW, Paramita S, Sukemi, Yadi, Tandirogang N, Takemoto N, Syafrizal, Kim YU, Shimizu K.
Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines
Saudi J Biol Sci
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Suzuka J, Tsuda M, Wang L, Kohsaka S, Kishida K, Semba S, Sugino H, Aburatani S, Frauenlob M, Kurokawa T, Kojima S, Ueno T, Ohmiya Y, Mano H, Yasuda K, Gong JP, Tanaka S.
Rapid reprogramming of tumour cells into cancer stem cells on double-network hydrogels
Nat Biomed Eng
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Small molecule targeting r(UGGAA) n disrupts RNA foci and alleviates disease phenotype in Drosophila model
Nat Commun
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Structure Elucidation of Calyxoside B, a Bipolar Sphingolipid from a Marine Sponge Cladocroce sp. through the Use of Beckmann Rearrangement.
Mar Drugs
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3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images
Elife
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Fayez S, Cacciatore A, Sun S, Kim M, Aké Assi L, Feineis D, Awale S, Bringmann G.
Ancistrobrevidines A-C and related naphthylisoquinoline alkaloids with cytotoxic activities against HeLa and pancreatic cancer cells, from the liana Ancistrocladus abbreviatus
Bioorg Med Chem
2021
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The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43
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Nakagami A, Mao Q, Gouhier G, Arima H, Kitagishi H.
FRET-Based In-Cell Detection of Highly Selective Supramolecular Complexes of meso-Tetraarylporphyrin with Peptide/BODIPY-Modified Per-O-Methyl-β-Cyclodextrins
Chembiochem
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Super-multiplex imaging of cellular dynamics and heterogeneity by integrated stimulated Raman and fluorescence microscopy
iScience
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Kazuyuki Todoroki, Mariko Funasaki, Tadahiro Etoh, Keiichi Matsuzaki, Ayumi Ohsaki
Two Erythrina alkaloids and three diarylpropanoids from Erythrina velutina
Tetrahedron
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Okada H, Mimura M, Tomita S, Kurita R.
Affinity Diversification of a Polymer Probe for Pattern-recognition-based Biosensing Using Chemical Additives
Anal Sci
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Nakamoto H, Katanosaka Y, Chijimatsu R, Mori D, Xuan F, Yano F, Omata Y, Maenohara Y, Murahashi Y, Kawaguchi K, Yamagami R, Inui H, Taketomi S, Taniguchi Y, Kanagawa M, Naruse K, Tanaka S, Saito T.
Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage
Arthritis Rheumatol
2021
73(8):1441-1450
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Takuya Kataoka, Sadaki Samitsu, Mitsuhiro Okuda, Daisuke Kawagoe, Motohiro Tagaya
Highly Luminescent Hydroxyapatite Nanoparticles Hybridized with Citric Acid for Their Bifunctional Cell-Labeling and Cytostatic Suppression Properties
ACS Applied Nano Materials
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Nagasawa I, Muroi M, Kawatani M, Ohishi T, Ohba SI, Kawada M, Osada H.
Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA.
Cell Chem Biol
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27(2):186-196
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Hamao K, Ono T, Matsushita M, Hosoya H.
ZIP kinase phosphorylated and activated by Rho kinase/ROCK contributes to cytokinesis in mammalian cultured cells.
Exp Cell Res
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386(1):111707
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Mai T T Nguyen, Khang D H Nguyen, Phu H Dang, Hai X Nguyen, Suresh Awale 1, Nhan T Nguyen
Calosides A-F, Cardenolides From Calotropis gigantea and Their Cytotoxic Activity
J Nat Prod
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Ryosuke Koyama, Yui Kano, Kaori Kikushima, Ayaka Mizutani, Yuta Soeda, Kazuki Miura, Takako Hirano, Toshiyuki Nishio, Wataru Hakamata
A Novel Golgi Mannosidase Inhibitor: Molecular Design, Synthesis, Enzyme Inhibition, and Inhibition of Spheroid Formation
Bioorg Med Chem
2020
28(11):115492
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Wada Y, Kikuchi A, Kaga A, Shimizu N, Ito J, Onuma R, Fujishima F, Totsune E, Sato R, Niihori T, Shirota M, Funayama R, Sato K, Nakazawa T, Nakayama K, Aoki Y, Aiba S, Nakagawa K, Kure S.
Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice.
PLoS Genet.
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Chemical manipulations to facilitate membrane blebbing and vesicle shedding on the cellular cortex.
Biotechnol. Lett.
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Tomoko G. Oyama, Atsushi Kimura, Naotsugu Nagasawa, Kotaro Oyama and Mitsumasa Taguchi
Development of Advanced Biodevices Using Quantum Beam Microfabrication Technology
Quantum Beam Sci
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Nagai M, Kato K, Soga S, Santra TS, Shibata T.
Scalable Parallel Manipulation of Single Cells Using Micronozzle Array Integrated with Bidirectional Electrokinetic Pumps.
Micromachines (Basel)
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Sano M, Yada R, Nomura Y, Kusukawa T, Ando H, Matsumoto K, Wada K, Tanaka T, Ohara H, Aso Y.
Microbial Screening Based on the Mizoroki-Heck Reaction Permits Exploration of Hydroxyhexylitaconic-Acid-Producing Fungi in Soils.
Microorganisms
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Kojima H, Itoh T.
Preparation and Use of Turn-on Fluorescent Probe for Detection and Live Cell Imaging of Vitamin D Receptor as a Target Protein.
STAR Protoc
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PubMed ID: 33111084
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Ishihara K, Mitera K, Inoue Y, Fukazawa K.
Effects of molecular interactions at various polymer brush surfaces on fibronectin adsorption induced cell adhesion.
Colloids Surf B Biointerfaces
2020
PubMed ID: 32592945
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Nagayama K, Ohata S, Obata S, Sato A.
Macroscopic and microscopic analysis of the mechanical properties and adhesion force of cells using a single cell tensile test and atomic force microscopy: Remarkable differences in cell types.
J Mech Behav Biomed Mater
2020
PubMed ID: 32957229
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Miyano K, Okamoto S, Yamauchi A, Kawai C, Kajikawa M, Kiyohara T, Tamura M, Taura M, Kuribayashi F.
The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein.
J Biol Chem
2020
PubMed ID: 32616654
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Matsuura Y, Noguchi A, Sakai S, Yokota N, Kawahara H.
Nuclear accumulation of ZFP36L1 is cell cycle-dependent and determined by a C-terminal serine-rich cluster.
J Biochem
2020
PubMed ID: 32687160
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Miura K, Onodera C, Takagi M, Koyama R, Hirano T, Nishio T, Hakamata W.
Screening, Synthesis, and Evaluation of Novel Isoflavone Derivatives as Inhibitors of Human Golgi β-Galactosidase.
Chem Pharm Bull (Tokyo)
2020
PubMed ID: 32741916
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Fang J, Gao S, Islam R, Teramoto Y, Maeda H.
Extracts of Phellinus linteus, Bamboo (Sasa senanensis) Leaf and Chaga Mushroom (Inonotus obliquus) Exhibit Antitumor Activity through Activating Innate Immunity.
Nutrients
2020
PubMed ID: 32751371
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Ertunc N, Sato C, Kitajima K.
Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.
Biosci Biotechnol Biochem
2020
PubMed ID: 32752946
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Yamanaka R, Shindo Y, Hotta K, Hiroi N, Oka K.
Cellular thermogenesis compensates environmental temperature fluctuations for maintaining intracellular temperature.
Biochem Biophys Res Commun
2020
PubMed ID: 32928506
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Ono T, Terada F, Okumura M, Chihara T, Hamao K.
Impairment of cytokinesis by cancer-associated DAPK3 mutations.
Biochem Biophys Res Commun
2020
PubMed ID: 33032825
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Nakane W, Nakamura H, Nakazato T, Kaminaga N, Nakano M, Sakamoto T, Nishiko M, Bono H, Ogiwara I, Kitano Y, Iwabuchi K, Kinoshita K, Simpson RJ, Tabunoki H.
Construction of TUATinsecta database that integrated plant and insect database for screening phytophagous insect metabolic products with medicinal potential.
Sci Rep
2020
PubMed ID: 33060804
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Yanaizu M, Washizu C, Nukina N, Satoh JI, Kino Y.
CELF2 regulates the species-specific alternative splicing of TREM2.
Sci Rep
2020
PubMed ID: 33093587
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Kuwahara Y, Iehara T, Ichise E, Katsumi Y, Ouchi K, Tsuchiya K, Miyachi M, Konishi E, Sasajima H, Nakamura S, Fumino S, Tajiri T, Johann PD, FrÜhwald MC, Yoshida T, Okuda T, Hosoi H.
Novel Two MRT Cell Lines Established from Multiple Sites of a Synchronous MRT Patient.
Anticancer Res
2020
PubMed ID: 33109553
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Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J.
Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival.
Sci Rep
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PubMed ID: 33144618
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Chinnathambi S, Hanagata N, Yamazaki T, Shirahata N.
Nano-Bio Interaction between Blood Plasma Proteins and Water-Soluble Silicon Quantum Dots with Enabled Cellular Uptake and Minimal Cytotoxicity.
Nanomaterials (Basel)
2020
PubMed ID: 33202926
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Yokosawa T, Sato A, Wakasugi K.
Tryptophan Depletion Modulates Tryptophanyl-tRNA Synthetase-Mediated High-Affinity Tryptophan Uptake into Human Cells.
Genes (Basel)
2020
PubMed ID: 33261077
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13372
Nuryadi H, Sumimoto S, Teruya T, Suenaga K, Suda S.
Characterization of Macroscopic Colony-Forming Filamentous Cyanobacteria from Okinawan Coasts as Potential Sources of Bioactive Compounds.
Mar Biotechnol (NY)
2020
PubMed ID: 33244658
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13424
Hiroaki Kitagishi, Misa Jiromaru, and Naomi Hasegawa
Intracellular Delivery of Adamantane-Tagged Small Molecule, Proteins, and Liposomes Using an Octaarginine-Conjugated β-Cyclodextrin
ACS Appl. Bio Mater.
2020
PubMed ID: 35021734
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13445
Rahman Md Moshikur, Md. KorbanAli, Rie Wakabayashi, Muhammad Moniruzzaman, Masahiro Goto
Formation and potential application of micelles composed of biocompatible N-lauroyl-amino acid ionic liquids surfactant
Journal of Molecular Liquids
2020
DOI: 10.1016/j.molliq.2020.114424
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Ueno M, Matsunaga A, Teratake Y, Ishizaka Y.
Retrotransposition and senescence in mouse heart tissue by viral protein R of human immunodeficiency virus-1
Exp Mol Pathol
2020
114:104433
PubMed ID: 32243892
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13577
Shimada K, Kobayashi N, Oka N, Takahashi M, Kondo K.
Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B
Microbiol Immunol
2020
64(11):747-761
PubMed ID: 32910457
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13578
Tan A, Suzuki R, Yokoyama C, Yano S, Konno H.
Antimicrobial activity and secondary structure of a novel peptide derived from ovalbumin
J Pept Sci
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26(10):e3276
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Miura K, Aoyama Y, Natsu Y, Koyama R, Hirano T, Nishio T, Hakamata W.
Development of Specific Fluorogenic Substrates for Human β-N-Acetyl-D-hexosaminidase A for Cell-Based Assays
Chem Pharm Bull (Tokyo)
2020
68(6):526-53
PubMed ID: 32475856
DOI: 10.1248/cpb.c20-00069
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Chee Kei Kong, Yen Nee Tan, Fook Yee Chye, Nam Weng Sit
Nutritional composition and biological activities of the edible shoots of Bambusa vulgaris and Gigantochloa ligulata
Food Bioscience
2020
36:100650
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16416
Sugai H, Tomita S, Ishihara S, Yoshioka K, Kurita R.
Microfluidic Sensing System with a Multichannel Surface Plasmon Resonance Chip: Damage-Free Characterization of Cells by Pattern Recognition
Anal Chem
2020
92(22):14939-14946
PubMed ID: 33112611
DOI: 10.1021/acs.analchem.0c02220
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Wakabayashi K, Sakurai F, Ono R, Fujiwara T, Mizuguchi H.
Development of a Novel Oncolytic Adenovirus Expressing a Short-hairpin RNA Against Cullin 4A
Anticancer Res
2020
40(1):161-168
PubMed ID: 31892564
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16625
Fayez S, Bruhn T, Feineis D, Assi LA, Awale S, Bringmann G.
Ancistrosecolines A-F, Unprecedented seco-Naphthylisoquinoline Alkaloids from the Roots of Ancistrocladus abbreviatus, with Apoptosis-Inducing Potential against HeLa Cancer Cells
J Nat Prod
2020
83(4):1139-1151
PubMed ID: 32125158
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16820
CK Kong, YN Tan, FY Chy, NW Sit
Nutritional compositions, biological activities, and phytochemical contents of the edible bamboo shoot, Dendrocalamus asper, from Malaysia
Food Research Journal
2020
27(3):546-556
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Ishihara K, Ito M, Fukazawa K, Inoue Y.
Interface of Phospholipid Polymer Grafting Layers to Analyze Functions of Immobilized Oligopeptides Involved in Cell Adhesion
ACS Biomater Sci Eng
2020
6(7):3984-3993
PubMed ID: 33463330
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Ahmed Ashour, Yhiya Amen, Ahmed E. Allam, Takashi Kudo, Maki Nagata, Koichiro Ohnuki, Kuniyoshi Shimizu
New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus
Phytochemistry Letters
2019
32:10-14
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Mitsuhashi H, Homma S, Beermann ML, Ishimaru S, Takeda H, Yu BK, Liu K, Duraiswamy S, Boyce FM, Miller JB.
Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers.
Sci Rep
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PubMed ID: 30783185
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Bannai H, Hirose M, Niwa F, Mikoshiba K.
Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators.
J Vis Exp
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PubMed ID: 30958464
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Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
2019
76(5):797-810
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Kurosawa N, Wakata Y, Ida K, Midorikawa A, Isobe M.
High throughput development of TCR-mimic antibody that targets survivin-2B80-88/HLA-A*A24 and its application in a bispecific T-cell engager.
Sci Rep
2019
PubMed ID: 31285464
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11675
Dr. Ze Yuan, Prof. Toshihiro Nakamura, Dr. Shanmugavel Chinnathambi, Prof. Yanbai Pu, Prof. Naoto Shirahata, Prof. Kiyoto Matsuishi
Facile Formation of Stable Water‐Dispersed Luminescent Silicon Nanocrystals by Laser Processing in Liquid: Toward Fluorescent Labeling for Bio‐Imaging
CHEMNANOMAT
2019
DOI: 10.1002/cnma.201900289
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p125 is localized in endoplasmic reticulum exit sites and involved in their organization.
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Apoptosis-mediated Cytotoxicity of Prodigiosin-Like Red Pigment Produced by gamma-Proteobacterium and Its Multiple Bioactivities
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Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye
Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines
J Agric Food Chem
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Hirohisa Matsushita, Hiroaki Kuwabara, Satoko Ishikawa, Masataka Mochizuki
Apoptosis Induced in Human Cell Lines by a Butanol Extract from Chlorophytum comosum Roots
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Evaluation of nuclear transfer and transcription of plasmid DNA condensed with protamine by microinjection: the use of a nuclear transfer score
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A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.
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Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins.
Bioconjug Chem
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High-level expression of the coxsackievirus and adenovirus receptor messenger RNA in osteosarcoma, Ewing's sarcoma, and benign neurogenic tumors among musculoskeletal tumors.
Clin Cancer Res
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Kazuhiko OCHIAI, Masami MORIMATSU2, Yasunaga YOSHIKAWA, Bunei SYUTO and Kazuyoshi HASHIZUM
Brca2 C-terminus interacts with Rad51 and contributes to nuclear focus for-mation in double-strand break repair of DNA
Biomedical Research
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NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence.
Mol Biol Cell
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Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex.
J Biol Chem
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Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein.
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Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.
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Glutathione S-transferase P1 has protective effects on cell viability against camptothecin
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The 14-3-3 protein epsilon isoform expressed in reactive astrocytes in demyelinating lesions of multiple sclerosis binds to vimentin and glial fibrillary acidic protein in cultured human astrocytes
Am J Pathol
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Inhibition of attachment of virions of Norwalk virus to mammalian cells by soluble histone molecules.
Arch Virol
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Gaf-1b is an alternative splice variant of Gaf-1/Rip11.
Biochem Biophys Res Commun
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SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation.
Mol Biol Cell
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Remarkably size-regulated cell invasion by artificial viruses. Saccharide-dependent self-aggregation of glycoviruses and its consequences in glycoviral gene delivery.
J Am Chem Soc
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Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines.
Toxicol Sci
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Masahiro Nagahama, Shinya Hayashi, Shinsuke Morimitsu, Jun Sakurai
Biological Activities and Pore Formation of Clostridium Perfringens Beta Toxin in HL 60 Cells
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Ca(2+)-dependent and caspase-3-independent apoptosis caused by damage in Golgi apparatus due to 2,4,5,7-tetrabromorhodamine 123 bromide-induced photodynamic effects
Photochem Photobiol
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Jpn J Cancer Res
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Possible existence of common internalization mechanisms among arginine-rich peptides.
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Takashi KANAZAWA, Masahiko WATANABE, Fumihiko KANZAWA, Yuko MATSUSHIMA-HIBIYA, Kotaro KOYAMA, Noriaki TANAKA, Takashi SUGIMURA, Keiji WAKABAYASHI
Pierisin-1 from cabbage butterfly suppresses HeLa tumor growth in nude mice
Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences
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MASAKI YODA, KEISUKE G TAKAHASHI, KATSUYOSHI MORI
Telomerase activity detected in eyed embryos of rainbow trout Oncorhynchus mykiss
Fisheries Science
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MASAKI YODA, KEISUKE G. TAKAHASHI, KATSUYOSHI MORI
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Fisheries science
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Selective antiproliferative activity of caffeic acid phenethyl ester analogues on highly liver-metastatic murine colon 26-L5 carcinoma cell line
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Hepatitis C virus core protein inhibits apoptosis via enhanced Bcl-xL expression
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Role of the UL25 Gene Product in Packaging DNA Into the Herpes Simplex Virus Capsid: Location of UL25 Product in the Capsid and Demonstration That It Binds DNA
J Virol
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