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Cell No. : Cell Name
RCB0007 : HeLa  update : 2022/05/12
CommentHuman cell line derived from cervical cancer.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Soeda, Eiichi
Originator Gey, G. O. et al.
Year of deposit 1986
Animal human < Mammals
Genus Homo
Species sapiens
Gender Female
Age at sampling 31 years
Tissue cervix
Disease name cervical carcinoma
Classification cancer
Year of origin 1952
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_0030
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 10% CS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 1-2 times/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
STR(human) OK
deposit info
lot info
Reference information Reference 3
User's Publication 386

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4660  EAGLE H.  The minimum vitamin requirements of the L and HeLa cells in tissue culture, the production of specific vitamin deficiencies, and their cure.  J Exp Med  1955  102(5):595-600  PubMed ID: 13271674
150  Gey,G.O., Coffman,W.D. and Kubicek,M.T.  Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium.  Cancer Res  1952  12:264-265 

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User's Publication
16222  Xiaobo Yin, Takayuki Konishi, Kazuo Horikawa, Ryota Tanaka, Yuki Togo, Takanori Noda, Miho Hosoi, Mie Tsuchida, Tatsuki Kunoh, Shuichi Wada, Toshinobu Nakamura, Eisuke Tsuda, Ryuzo Sasaki, Tamio Mizukami, Makoto Hasegawa  Structure and Function of Potential Glycosylation Sites of Dynactin-Associated Protein dynAP  Mol Biotechnol  2022  Jan 13  PubMed ID: 35022995
16386  Haraguchi T, Koujin T, Shindo T, Bilir Ş, Osakada H, Nishimura K, Hirano Y, Asakawa H, Mori C, Kobayashi S, Okada Y, Chikashige Y, Fukagawa T, Shibata S, Hiraoka Y.  Transfected plasmid DNA is incorporated into the nucleus via nuclear envelope reformation at telophase  Commun Biol  2022  5(1):78  PubMed ID: 35058555
16391  Sakamoto T, Yu Z, Otani Y.  Dual-Color Fluorescence Switch-On Probe for Imaging G-Quadruplex and Double-Stranded DNA in Living Cells  Anal Chem  2022  Mar 2  PubMed ID: 35234461
16428  Fukushima S, Shimohata T, Inoue Y, Kido J, Uebanso T, Mawatari K, Takahashi A.  Recruitment of LC3 by Campylobacter jejuni to Bacterial Invasion Site on Host Cells via the Rac1-Mediated Signaling Pathway  Front Cell Infect Microbiol  2022  12:829682  PubMed ID: 35310852
20613  Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.  Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.  Analyst  2022    PubMed ID: 35297918
20645  Oda R, Shou J, Zhong W, Ozeki Y, Yasui M, Nuriya M.  Direct visualization of general anesthetic propofol on neurons by stimulated Raman scattering microscopy.  iScience  2022  25(3):103936  PubMed ID: 35252821
20659  Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.  Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.  EMBO Rep  2022  e54801  PubMed ID: 35417087
20669  Nakahata M, Tominaga N, Saito K, Nishiyama K, Tanino Y, Saiki K, Kojima M, Sakai S.  A bio-synthetic hybrid hydrogel formed under physiological conditions consisting of mucin and a synthetic polymer carrying boronic acid.  Macromol Biosci  2022  e2200055  PubMed ID: 35429097
16520  Nagayama K, Hanzawa T.  Cell type-specific orientation and migration responses for a microgrooved surface with shallow grooves  Biomed Mater Eng  2022  Feb 14  PubMed ID: 35180105
20725  Inagaki E, Arai E, Hatou S, Sayano T, Taniguchi H, Negishi K, Kanai Y, Sato Y, Okano H, Tsubota K, Shimmura S.  The Anterior Eye Chamber as a Visible Medium for In Vivo Tumorigenicity Tests.  Stem Cells Transl Med  2022    PubMed ID: 35666752
13251  Saito M.  Fluorescent Labeling of Connexin with As Complex and X-Y Coordinate Registration of Target Single Cells Based on a Triangle Standard Chip for the Image Analysis of Gap Junctional Communication.  Methods Mol Biol  2021    PubMed ID: 32989705
13367  Yamaguchi K, Otomo K, Kozawa Y, Tsutsumi M, Inose T, Hirai K, Sato S, Nemoto T, Uji-I H.  Adaptive Optical Two-Photon Microscopy for Surface-Profiled Living Biological Specimens.  ACS Omega  2021    PubMed ID: 33458495
20001  Fukuchi M, Oyama K, Mizuno H, Miyagawa A, Koumoto K, Fukuhara G.  Hydrostatic Pressure-Regulated Cellular Calcium Responses.  Langmuir  2021  37(2) 820-826  PubMed ID: 33410684
13463  Shota Someya et al  Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells  iScienc  2021  24  PubMed ID: 33615198
20019  Chau S, Fujii A, Wang Y, Vandebroek A, Goda W, Yasui M, Abe Y.  Di-lysine motif-like sequences formed by deleting the C-terminal domain of aquaporin-4 prevent its trafficking to the plasma membrane.  Genes Cells  2021    PubMed ID: 33474763
20040  Nara T, Nakagawa Y, Tsuganezawa K, Yuki H, Sekimata K, Koyama H, Ogawa N, Honma T, Shirouzu M, Fukami T, Matsuo Y, Inaoka DK, Kita K, Tanaka A.  The ubiquinone synthesis pathway is a promising drug target for Chagas disease.  PLoS One  2021  16(2):e0243855  PubMed ID: 33539347
20048  Liu X, Suyama K, Nose T, Shimohigashi M, Shimohigashi Y.  Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding.  PLoS One  2021  16(2):e0246583  PubMed ID: 33561155
20078  Chukai Y, Iwamoto T, Itoh K, Tomita H, Ozaki T.  Characterization of mitochondrial calpain-5.  Biochim Biophys Acta Mol Cell Res  2021  1868(5):118989  PubMed ID: 33607190
20112  Liu X, Matsuyama Y, Shimohigashi M, Shimohigashi Y.  ERα-agonist and ERβ-antagonist bifunctional next-generation bisphenols with no halogens: BPAP, BPB, and BPZ.  Toxicol Lett  2021  345:24-33  PubMed ID: 33857583
14002  Vong K, Tahara T, Urano S, Nasibullin I, Tsubokura K, Nakao Y, Kurbangalieva A, Onoe H, Watanabe Y, Tanaka K. タイトル   Disrupting tumor onset and growth via selective cell tagging (SeCT) therapy  Sci Adv  2021  7(17):eabg4038  PubMed ID: 33893089
14183  Okawa F, Hama Y, Zhang S, Morishita H, Yamamoto H, Levine TP, Mizushima N.  Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1  J Cell Sci  2021  134(8):jcs255877  PubMed ID: 33771928
20153  Yin X, Yamada S, Kobayashi H, Tanaka R, Togo Y, Hosoi M, Tsuchida M, Kunoh T, Wada S, Nakamura T, Sasaki R, Mizukami T, Hasegawa M.  Expression and cell transformation activity of dynactin-associated protein isoforms.  FEBS Open Bio  2021    PubMed ID: 34043884
20156  Oyama TG, Oyama K, Kimura A, Yoshida F, Ishida R, Yamazaki M, Miyoshi H, Taguchi M.  Collagen hydrogels with controllable combined cues of elasticity and topography to regulate cellular processes.  Biomed Mater  2021    PubMed ID: 34030146
20003  Inaba H, Miao Q, Nakata T.  Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling  Biol Chem  2021  296:100290  PubMed ID: 33453281
14869  Torii C, Maishi N, Kawamoto T, Morimoto M, Akiyama K, Yoshioka Y, Minami T, Tsumita T, Alam MT, Ochiya T, Hida Y, Hida K.  miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells  Sci Rep  2021  11(1):13502  PubMed ID: 34226586
15011  Sekino Y, Imaizumi A, Komune N, Ono M, Sato K, Masuda S, Fujimura A, Koike K, Hongo T, Uchi R, Onishi H, Nakagawa T.  Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma  FEBS Open Bio  2021  Jun 11  PubMed ID: 34115931
20253  Yanagi T, Kaminaga K, Suzuki M, Abe H, Yamamoto H, Ohshima T, Kuwahata A, Sekino M, Imaoka T, Kakinuma S, Sugi T, Kada W, Hanaizumi O, Igarashi R.  All-Optical Wide-Field Selective Imaging of Fluorescent Nanodiamonds in Cells, In Vivo and Ex Vivo.  ACS Nano  2021    PubMed ID: 34339180
20290  Kimura A, Ueno M, Arai T, Oyama K, Taguchi M.  Radiation Crosslinked Smart Peptide Nanoparticles: A New Platform for Tumor Imaging.  Nanomaterials (Basel)  2021  11(3) 
20291  Kowada T, Watanabe T, Liu R, Mizukami S.  Protocol for synthesis and use of a turn-on fluorescent probe for quantifying labile Zn2+ in the Golgi apparatus in live cells.  STAR Protoc  2021  2(2)  PubMed ID: 33796872
20310  Endo-Takahashi Y, Kurokawa R, Sato K, Takizawa N, Katagiri F, Hamano N, Suzuki R, Maruyama K, Nomizu M, Takagi N, Negishi Y.  Ternary Complexes of pDNA, Neuron-Binding Peptide, and PEGylated Polyethyleneimine for Brain Delivery with Nano-Bubbles and Ultrasound.  Pharmaceutics  2021  13(7):  PubMed ID: 34371694
15504  Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, Ozawa M, Saitou M, Shinkai Y, Yamamoto T, Yamada Y.  DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency  Nat Commun  2021  12(1):5041  PubMed ID: 34413299
15520  Tomoko Gowa Oyama, Kotaro Oyama, Hiromi Miyoshi, Mitsumasa Taguchi  3D cell sheets formed via cell-driven buckling-delamination of patterned thin films  Materials & Design  2021  208:109975 
20364  Fukasawa K, Gotoh M, Uwamizu A, Hirokawa T, Ishikawa M, Shimizu Y, Yamamoto S, Iwasa K, Yoshikawa K, Aoki J, Murakami-Murofushi K.  2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition.  Sci Rep  2021  11(1):17360  PubMed ID: 34462512
20374  Kato S, Arasaki K, Tokutomi N, Imai Y, Inoshita T, Hattori N, Sasaki T, Sato M, Wakana Y, Inoue H, Tagaya M.  Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms.  J Cell Sci  2021    PubMed ID: 34704591
20402  Yahiro K, Ogura K, Tsutsuki H, Iyoda S, Ohnishi M, Moss J.  A novel endoplasmic stress mediator, Kelch domain containing 7B (KLHDC7B), increased Harakiri (HRK) in the SubAB-induced apoptosis signaling pathway.  Cell Death Discov  2021  7(1):360  PubMed ID: 34799565
20404  Okada T, Nishida S, Zhang L, Ibrahim Mohamed NN, Wang T, Ijuin T, Kajimoto T, Nakamura SI.  Constitutive activation of S1P receptors at the trans-Golgi network is required for surface transport carrier formation.  iScience  2021  24(11):103351  PubMed ID: 34805799
20406  Sawa C, Yofu S, Kiriyama K, Sutoh K, Saito T, Kishi S, Gunji M, Inoue Y, Sugi M, Shioda S, Honda K.  High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.  Heliyon  2021  7(11):e08318  PubMed ID: 34816032
15887  See K, Kadonosono T, Miyamoto K, Tsubaki T, Ota Y, Katsumi M, Ryo S, Aida K, Minegishi M, Isozaki T, Kuchimaru T, Kizaka-Kondoh S.  Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display  Sci Rep  2021  11(1):22098  PubMed ID: 34764369
20503  Tsuzuki H, Nagatsuka Y, Iwata M, Kitamura N, Nagasawa Y, Matsumoto T, Ito R, Takahashi T, Ito M, Nakamura H, Takei M.  Antinuclear antibodies produced in HLA-DR transgenic humanized mice developed chronic graft-versus-host disease.  Heliyon  2021  7(11):e08380  PubMed ID: 34825089
16049  Endo A, Asayama S.  Hepatocyte-Specific Co-Delivery of Zinc Ions and Plasmid DNA by Lactosylated Poly(1-vinylimidazole) for Suppression of Insulin Receptor Internalization  Pharmaceutics  2021  13(12):2084  PubMed ID: 34959365
16102  Arung ET, Ramadhan R, Khairunnisa B, Amen Y, Matsumoto M, Nagata M, Kusuma IW, Paramita S, Sukemi, Yadi, Tandirogang N, Takemoto N, Syafrizal, Kim YU, Shimizu K.  Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines  Saudi J Biol Sci  2021  ;28(12):7182-7189  PubMed ID: 34867021
16173  Suzuka J, Tsuda M, Wang L, Kohsaka S, Kishida K, Semba S, Sugino H, Aburatani S, Frauenlob M, Kurokawa T, Kojima S, Ueno T, Ohmiya Y, Mano H, Yasuda K, Gong JP, Tanaka S.  Rapid reprogramming of tumour cells into cancer stem cells on double-network hydrogels  Nat Biomed Eng  2021  5(8):914-925  PubMed ID: 33782572
16283  Shibata T, Nagano K, Ueyama M, Ninomiya K, Hirose T, Nagai Y, Ishikawa K, Kawai G, Nakatani K.  Small molecule targeting r(UGGAA) n disrupts RNA foci and alleviates disease phenotype in Drosophila model  Nat Commun  2021  12(1):236  PubMed ID: 33431896
20672  Sugawara K, Watarai H, Ise Y, Yokose H, Morii Y, Yamawaki N, Okada S, Matsunaga S.  Structure Elucidation of Calyxoside B, a Bipolar Sphingolipid from a Marine Sponge Cladocroce sp. through the Use of Beckmann Rearrangement.  Mar Drugs  2021  19(6)  PubMed ID: 34063932
16519  Wen C, Miura T, Voleti V, Yamaguchi K, Tsutsumi M, Yamamoto K, Otomo K, Fujie Y, Teramoto T, Ishihara T, Aoki K, Nemoto T, Hillman EM, Kimura KD.  3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images  Elife  2021  10:e59187.  PubMed ID: 33781383
16627  Fayez S, Cacciatore A, Sun S, Kim M, Aké Assi L, Feineis D, Awale S, Bringmann G.  Ancistrobrevidines A-C and related naphthylisoquinoline alkaloids with cytotoxic activities against HeLa and pancreatic cancer cells, from the liana Ancistrocladus abbreviatus  Bioorg Med Chem  2021  30:115950  PubMed ID: 33383442
6918  Nagasawa I, Muroi M, Kawatani M, Ohishi T, Ohba SI, Kawada M, Osada H.  Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA.  Cell Chem Biol  2020  27(2):186-196  PubMed ID: 31813846
6961  Hamao K, Ono T, Matsushita M, Hosoya H.  ZIP kinase phosphorylated and activated by Rho kinase/ROCK contributes to cytokinesis in mammalian cultured cells.  Exp Cell Res  2020  386(1):111707  PubMed ID: 31693874
9820  Mai T T Nguyen, Khang D H Nguyen, Phu H Dang, Hai X Nguyen, Suresh Awale 1, Nhan T Nguyen  Calosides A-F, Cardenolides From Calotropis gigantea and Their Cytotoxic Activity  J Nat Prod  2020  83(2):385-391  PubMed ID: 31967821
9937  Ryosuke Koyama, Yui Kano, Kaori Kikushima, Ayaka Mizutani, Yuta Soeda, Kazuki Miura, Takako Hirano, Toshiyuki Nishio, Wataru Hakamata  A Novel Golgi Mannosidase Inhibitor: Molecular Design, Synthesis, Enzyme Inhibition, and Inhibition of Spheroid Formation  Bioorg Med Chem  2020  28(11):115492  PubMed ID: 32291147
12067  Wada Y, Kikuchi A, Kaga A, Shimizu N, Ito J, Onuma R, Fujishima F, Totsune E, Sato R, Niihori T, Shirota M, Funayama R, Sato K, Nakazawa T, Nakayama K, Aoki Y, Aiba S, Nakagawa K, Kure S.  Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice.  PLoS Genet.  2020    PubMed ID: 32101538
12069  Okada S, Fukai Y, Yoshimoto F, Saitoh H.  Chemical manipulations to facilitate membrane blebbing and vesicle shedding on the cellular cortex.  Biotechnol. Lett.  2020  42(7)  PubMed ID: 32112174
12155  Tomoko G. Oyama, Atsushi Kimura, Naotsugu Nagasawa, Kotaro Oyama and Mitsumasa Taguchi  Development of Advanced Biodevices Using Quantum Beam Microfabrication Technology  Quantum Beam Sci  2020   
12996  Nagai M, Kato K, Soga S, Santra TS, Shibata T.  Scalable Parallel Manipulation of Single Cells Using Micronozzle Array Integrated with Bidirectional Electrokinetic Pumps.  Micromachines (Basel)  2020    PubMed ID: 32331468
13016  Sano M, Yada R, Nomura Y, Kusukawa T, Ando H, Matsumoto K, Wada K, Tanaka T, Ohara H, Aso Y.  Microbial Screening Based on the Mizoroki-Heck Reaction Permits Exploration of Hydroxyhexylitaconic-Acid-Producing Fungi in Soils.  Microorganisms  2020    PubMed ID: 32365722
13055  Kojima H, Itoh T.  Preparation and Use of Turn-on Fluorescent Probe for Detection and Live Cell Imaging of Vitamin D Receptor as a Target Protein.  STAR Protoc  2020    PubMed ID: 33111084
13075  Ishihara K, Mitera K, Inoue Y, Fukazawa K.  Effects of molecular interactions at various polymer brush surfaces on fibronectin adsorption induced cell adhesion.  Colloids Surf B Biointerfaces  2020    PubMed ID: 32592945
13096  Nagayama K, Ohata S, Obata S, Sato A.  Macroscopic and microscopic analysis of the mechanical properties and adhesion force of cells using a single cell tensile test and atomic force microscopy: Remarkable differences in cell types.  J Mech Behav Biomed Mater  2020    PubMed ID: 32957229
13098  Miyano K, Okamoto S, Yamauchi A, Kawai C, Kajikawa M, Kiyohara T, Tamura M, Taura M, Kuribayashi F.  The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein.  J Biol Chem  2020    PubMed ID: 32616654
13117  Matsuura Y, Noguchi A, Sakai S, Yokota N, Kawahara H.  Nuclear accumulation of ZFP36L1 is cell cycle-dependent and determined by a C-terminal serine-rich cluster.  J Biochem  2020    PubMed ID: 32687160
13135  Miura K, Onodera C, Takagi M, Koyama R, Hirano T, Nishio T, Hakamata W.  Screening, Synthesis, and Evaluation of Novel Isoflavone Derivatives as Inhibitors of Human Golgi β-Galactosidase.  Chem Pharm Bull (Tokyo)  2020    PubMed ID: 32741916
13140  Fang J, Gao S, Islam R, Teramoto Y, Maeda H.  Extracts of Phellinus linteus, Bamboo (Sasa senanensis) Leaf and Chaga Mushroom (Inonotus obliquus) Exhibit Antitumor Activity through Activating Innate Immunity.  Nutrients  2020    PubMed ID: 32751371
13146  Ertunc N, Sato C, Kitajima K.  Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.  Biosci Biotechnol Biochem  2020    PubMed ID: 32752946
13217  Yamanaka R, Shindo Y, Hotta K, Hiroi N, Oka K.  Cellular thermogenesis compensates environmental temperature fluctuations for maintaining intracellular temperature.  Biochem Biophys Res Commun  2020    PubMed ID: 32928506
13265  Ono T, Terada F, Okumura M, Chihara T, Hamao K.  Impairment of cytokinesis by cancer-associated DAPK3 mutations.  Biochem Biophys Res Commun  2020    PubMed ID: 33032825
13290  Nakane W, Nakamura H, Nakazato T, Kaminaga N, Nakano M, Sakamoto T, Nishiko M, Bono H, Ogiwara I, Kitano Y, Iwabuchi K, Kinoshita K, Simpson RJ, Tabunoki H.  Construction of TUATinsecta database that integrated plant and insect database for screening phytophagous insect metabolic products with medicinal potential.  Sci Rep  2020    PubMed ID: 33060804
13307  Yanaizu M, Washizu C, Nukina N, Satoh JI, Kino Y.  CELF2 regulates the species-specific alternative splicing of TREM2.  Sci Rep  2020    PubMed ID: 33093587
13312  Kuwahara Y, Iehara T, Ichise E, Katsumi Y, Ouchi K, Tsuchiya K, Miyachi M, Konishi E, Sasajima H, Nakamura S, Fumino S, Tajiri T, Johann PD, FrÜhwald MC, Yoshida T, Okuda T, Hosoi H.  Novel Two MRT Cell Lines Established from Multiple Sites of a Synchronous MRT Patient.  Anticancer Res  2020    PubMed ID: 33109553
13324  Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J.  Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival.  Sci Rep  2020    PubMed ID: 33144618
13342  Chinnathambi S, Hanagata N, Yamazaki T, Shirahata N.  Nano-Bio Interaction between Blood Plasma Proteins and Water-Soluble Silicon Quantum Dots with Enabled Cellular Uptake and Minimal Cytotoxicity.  Nanomaterials (Basel)  2020    PubMed ID: 33202926
13363  Yokosawa T, Sato A, Wakasugi K.  Tryptophan Depletion Modulates Tryptophanyl-tRNA Synthetase-Mediated High-Affinity Tryptophan Uptake into Human Cells.  Genes (Basel)  2020    PubMed ID: 33261077
13372  Nuryadi H, Sumimoto S, Teruya T, Suenaga K, Suda S.  Characterization of Macroscopic Colony-Forming Filamentous Cyanobacteria from Okinawan Coasts as Potential Sources of Bioactive Compounds.  Mar Biotechnol (NY)  2020    PubMed ID: 33244658
13424  Hiroaki Kitagishi, Misa Jiromaru, and Naomi Hasegawa  Intracellular Delivery of Adamantane-Tagged Small Molecule, Proteins, and Liposomes Using an Octaarginine-Conjugated β-Cyclodextrin  ACS Appl. Bio Mater.  2020   
13445  Rahman Md Moshikur, Md. KorbanAli, Rie Wakabayashi, Muhammad Moniruzzaman, Masahiro Goto  Formation and potential application of micelles composed of biocompatible N-lauroyl-amino acid ionic liquids surfactant  Journal of Molecular Liquids  2020   
13498  Ueno M, Matsunaga A, Teratake Y, Ishizaka Y.  Retrotransposition and senescence in mouse heart tissue by viral protein R of human immunodeficiency virus-1  Exp Mol Pathol  2020  114:104433  PubMed ID: 32243892
13577  Shimada K, Kobayashi N, Oka N, Takahashi M, Kondo K.  Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B  Microbiol Immunol  2020  64(11):747-761  PubMed ID: 32910457
13578  Tan A, Suzuki R, Yokoyama C, Yano S, Konno H.  Antimicrobial activity and secondary structure of a novel peptide derived from ovalbumin  J Pept Sci  2020  26(10):e3276  PubMed ID: 32715598
13846  Miura K, Aoyama Y, Natsu Y, Koyama R, Hirano T, Nishio T, Hakamata W.  Development of Specific Fluorogenic Substrates for Human β-N-Acetyl-D-hexosaminidase A for Cell-Based Assays  Chem Pharm Bull (Tokyo)  2020  68(6):526-53  PubMed ID: 32475856
14874  Chee Kei Kong, Yen Nee Tan, Fook Yee Chye, Nam Weng Sit  Nutritional composition and biological activities of the edible shoots of Bambusa vulgaris and Gigantochloa ligulata  Food Bioscience  2020  36:100650 
16416  Sugai H, Tomita S, Ishihara S, Yoshioka K, Kurita R.  Microfluidic Sensing System with a Multichannel Surface Plasmon Resonance Chip: Damage-Free Characterization of Cells by Pattern Recognition  Anal Chem  2020  92(22):14939-14946  PubMed ID: 33112611
16623  Wakabayashi K, Sakurai F, Ono R, Fujiwara T, Mizuguchi H.  Development of a Novel Oncolytic Adenovirus Expressing a Short-hairpin RNA Against Cullin 4A  Anticancer Res  2020  40(1):161-168  PubMed ID: 31892564
16625  Fayez S, Bruhn T, Feineis D, Assi LA, Awale S, Bringmann G.  Ancistrosecolines A-F, Unprecedented seco-Naphthylisoquinoline Alkaloids from the Roots of Ancistrocladus abbreviatus, with Apoptosis-Inducing Potential against HeLa Cancer Cells  J Nat Prod  2020  83(4):1139-1151  PubMed ID: 32125158
11444  Mitsuhashi H, Homma S, Beermann ML, Ishimaru S, Takeda H, Yu BK, Liu K, Duraiswamy S, Boyce FM, Miller JB.  Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers.  Sci Rep  2019    PubMed ID: 30783185
11492  Bannai H, Hirose M, Niwa F, Mikoshiba K.  Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators.  J Vis Exp  2019    PubMed ID: 30958464
5344  Tomoko Gowa Oyama, View ORCID ProfileKotaro Oyama, Atsushi Kimura, Fumiya Yoshida, Ryo Ishida, Masashi Yamazaki, Hiromi Miyoshi, View ORCID ProfileMitsumasa Taguchi  Elasticity and Topography-Controlled Collagen Hydrogels Mimicking Native Cellular Milieus  bioRxiv  2019  July 18 
5357  Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.  Mol Cell  2019  76(5):797-810  PubMed ID: 31606272
11625  Kurosawa N, Wakata Y, Ida K, Midorikawa A, Isobe M.  High throughput development of TCR-mimic antibody that targets survivin-2B80-88/HLA-A*A24 and its application in a bispecific T-cell engager.  Sci Rep  2019    PubMed ID: 31285464
11675  Dr. Ze Yuan, Prof. Toshihiro Nakamura, Dr. Shanmugavel Chinnathambi, Prof. Yanbai Pu, Prof. Naoto Shirahata, Prof. Kiyoto Matsuishi  Facile Formation of Stable Water‐Dispersed Luminescent Silicon Nanocrystals by Laser Processing in Liquid: Toward Fluorescent Labeling for Bio‐Imaging  CHEMNANOMAT  2019   
11756  Hirano K, Fujimaki M, Sasazawa Y, Yamaguchi A, Ishikawa KI, Miyamoto K, Souma S, Furuya N, Imamichi Y, Yamada D, Saya H, Akamatsu W, Saiki S, Hattori N.  Neuroprotective effects of memantine via enhancement of autophagy.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31431260
11805  Kikuchi S, Noguchi K, Wakai K, Hamazaki Y, Tozawa K, Jomori T, Sasako M, Miwa H.  Propagermanium Induces NK Cell Maturation and Tends to Prolong Overall Survival of Patients With Refractory Cancer.  Anticancer Res.  2019    PubMed ID: 31519568
4508  Kawai T, Ota N, Okada K, Imasato A, Owa Y, Morita M, Tada M, Tanaka Y.  Ultrasensitive Single Cell Metabolomics by Capillary Electrophoresis-Mass Spectrometry with a Thin-Walled Tapered Emitter and Large-Volume Dual Sample Preconcentration.  Anal Chem  2019  91(16):10564-10572  PubMed ID: 31357863
6914  Matsuura R, Inabe K, Otsuki H, Kurokawa K, Dohmae N, Aida Y.  Three YXXL Sequences of a Bovine Leukemia Virus Transmembrane Protein are Independently Required for Fusion Activity by Controlling Expression on the Cell Membrane.  Viruses  2019  11(12):1140  PubMed ID: 31835517
9728  Sayaka Akieda-Asai, Hao Ma, Yukari Date  Palmitic Acid Induces Guanylin Gene Expression Through the Toll-like Receptor 4/nuclear factor-κB Pathway in Rat Macrophages  Am J Physiol Cell Physiol  2019  317(6):C1239-C1246  PubMed ID: 31553648
9939  Kazuki Miura, Takumi Tsukagoshi, Takako Hirano, Toshiyuki Nishio, Wataru Hakamata  Development of Fluorogenic Substrates of α-l-Fucosidase Useful for Inhibitor Screening and Gene-expression Profiling  ACS Med Chem Lett   2019  10(9):1309-1313  PubMed ID: 31531202
10594  Safrina Dyah Hardiningtyas, Rie Wakabayashi, Ryutaro Ishiyama, Yuki Owada, Masahiro Goto, Noriho Kamiya  Enhanced Potential of Therapeutic Applications of Curcumin Using Solid-in-Water Nanodispersion Technique  JOURNAL OF CHEMICAL ENGINEERING OF JAPAN  2019  5:138-143 
10597  Rahman Md.Moshikura Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara, Muhammad Moniruzzaman, Masahiro Goto  Ionic liquids with methotrexate moieties as a potential anticancer prodrug: Synthesis, characterization and solubility evaluation  Journal of Molecular Liquids  2019  278:226-233 
12286  Nilufar Rahimova, Hasan Babazada, Yuriko Higuchi, Fumiyoshi Yamashita, Mitsuru Hashida   Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells  Biochim Biophys Acta Mol Cell Res   2019  1866(2):190-198  PubMed ID: 30391277
12380  Chinnathambi S, Hanagata N.  Photostability of quantum dot micelles under ultraviolet irradiation  Luminescence  2019  34(5):472-479  PubMed ID: 30809921
12430  Moriguchi M, Watanabe T, Fujimuro M.  Capsaicin Induces ATF4 Translation with Upregulation of CHOP, GADD34 and PUMA  Biol Pharm Bull  2019  42(8):1428-1432  PubMed ID: 31366879
12431  Sato K, Sato M, Yokoyama M, Hirai M, Furuta A.  nfluence of Culture Conditions on Cell Proliferation in a Microfluidic Channel  Anal Sci  2019  35(1):49-56  PubMed ID: 30473567
12432  Nagase K, Hasegawa M, Ayano E, Maitani Y, Kanazawa H.  Effect of Polymer Phase Transition Behavior on Temperature-Responsive Polymer-Modified Liposomes for siRNA Transfection  Int J Mol Sci  2019  20(2):430  PubMed ID: 30669495
12433  Khanmohammadi M, Sakai S, Taya M.  Characterization of encapsulated cells within hyaluronic acid and alginate microcapsules produced via horseradish peroxidase-catalyzed crosslinking  J Biomater Sci Polym Ed  2019  30(4):295-307  PubMed ID: 30593259
12434  Takeuchi T, Tamura M, Ishiwata K, Hamasaki M, Hamano S, Arata Y, Hatanaka T.  Galectin-2 suppresses nematode development by binding to the invertebrate-specific galactoseβ1-4fucose glyco-epitope  Glycobiology  2019  29(6):504-512  PubMed ID: 30874734
12435  Baba Y, Yamamoto K, Yoshida W.  Multicolor bioluminescence resonance energy transfer assay for qua  Anal Bioanal Chem  2019  411(19):4765-4773  PubMed ID: 30659325
12436  Ozeki K, Sugiyama M, Akter KA, Nishiwaki K, Asano-Inami E, Senga T.  FAM98A is localized to stress granules and associates with multiple stress granule-localized proteins  Mol Cell Biochem  2019  451(1-2):107-115  PubMed ID: 29992460
12437  Hara N, Osago H, Hiyoshi M, Kobayashi-Miura M, Tsuchiya M.  Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry  PLoS One  2019  14(3):e0214000  PubMed ID: 30875389
12517  Satria D, Amen Y, Niwa Y, Ashour A, Allam AE, Shimizu K.  Lucidumol D, a new lanostane-type triterpene from fruiting bodies of Reishi (Ganoderma lingzhi)  Nat Prod Res  2019  33(2):189-195  PubMed ID: 29457741
16624  Hana Kimura, Kohei Arasaki, Moe Iitsuka, Mitsuo Tagaya  Syntaxin 17 Recruits ACSL3 to Lipid Microdomains in Lipid Droplet Biogenesis  Contact  2019  2:251525641983871 
16626  Wakabayashi K, Machitani M, Tachibana M, Sakurai F, Mizuguchi H.  A MicroRNA Derived from Adenovirus Virus-Associated RNAII Promotes Virus Infection via Posttranscriptional Gene Silencing  J Virol   2019  93(2):e01265-18  PubMed ID: 30355689
9502  Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.  PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.  Cancer Cell  2018  33:355-367.e7  PubMed ID: 29533781
9505  Yoshida W, Saikyo H, Nakabayashi K, Yoshioka H, Bay DH, Iida K, Kawai T, Hata K, Ikebukuro K, Nagasawa K, Karube I.  Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand.  Sci Rep  2018  8:3116  PubMed ID: 29449667
10629  Baba Y, Shigemi Z, Hara N, Moriguchi M, Ikeda M, Watanabe T, Fujimuro M.  Arctigenin induces the apoptosis of primary effusion lymphoma cells under conditions of glucose deprivation.  Int. J. Oncol.  2018  52:505-517  PubMed ID: 29207179
10751  Noguchi A, Adachi S, Yokota N, Hatta T, Natsume T, Kawahara H.  ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.  Biol Open  2018  7:  PubMed ID: 29449217
10807  Tsunoyama TA, Watanabe Y, Goto J, Naito K, Kasai RS, Suzuki KGN, Fujiwara TK, Kusumi A.  Super-long single-molecule tracking reveals dynamic-anchorage-induced integrin function.  Nat. Chem. Biol.  2018  14:497-506  PubMed ID: 29610485
10812  Morisaku T, Yui H.  Laser-induced surface deformation microscope for the study of the dynamic viscoelasticity of plasma membrane in a living cell.  Analyst  2018  143:2397-2404  PubMed ID: 29700531
11117  Tang Q, Onitsuka M, Tabata A, Tomoyasu T, Nagamune H.  Construction of Anti-HER2 Recombinants as Targeting Modules for a Drug-delivery System Against HER2-positive Cells.  Anticancer Res.  2018  38(7):4319-4325  PubMed ID: 29970568
11158  Matsumoto S, Caliskan N, Rodnina MV, Murata A, Nakatani K.  Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting.  Nucleic Acids Res.  2018  46(16):8079-8089  PubMed ID: 30085309
11494  Shima T, Morikawa M, Kaneshiro J, Kambara T, Kamimura S, Yagi T, Iwamoto H, Uemura S, Shigematsu H, Shirouzu M, Ichimura T, Watanabe TM, Nitta R, Okada Y, Hirokawa N.  Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport.  J. Cell Biol.  2018  217(12):4164-4183  PubMed ID: 30297389
4058  Inoue Y, Onodera Y, Ishihara K.  Initial Cell Adhesion onto a Phospholipid Polymer Brush Surface Modified with a Terminal Cell Adhesion Peptide.  ACS Appl Mater Interfaces  2018  10:15250-15257  PubMed ID: 29652126
4087  Ryo Taguchia, Takuya Teraia, Tasuku Uenoa, Toru Komatsua, Kenjiro Hanaokaa, Yasuteru Urano  A protein-coupled fluorescent probe for organelle-specific imaging of Na+  Sensors and Actuators B: Chemical   2018  265, 575-581 
4089  Taketoshi Kajimoto, Shun-ichi Nakamura   Quantitative Analysis of Cargo Density in Single-extracellular Vesicles by Imaging   bio-protocol  2018  8 
4205  Shintani Y, Hayata-Takano A, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H.  β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.  PLoS ONE  2018    PubMed ID: 29734363
4206  Miyamoto T, Mizuno N, Kosaka M, Fujitani Y, Ohno E, Ohtsuka A.  Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4-Positive Cancer Cell Population.  Stem Cells  2018    PubMed ID: 29770522
4207  Takahashi T, Mine Y, Okamoto T.  2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) Disrupts Carbohydrate Metabolism of HeLa Cells by Adduct Formation with Intracellular Free Sulfhydryl-Groups, and Induces ATP Depletion and Necrosis.  Biol. Pharm. Bull.  2018    PubMed ID: 30504682
4208  Suzuki T, Yanai Y, Nishigaki N, Nakatsu Y, Tsuzuki T, Kamiya H.  Effects of mismatches distant from the target position on gene correction with a 5'-tailed duplex.  J. Biosci. Bioeng.  2018    PubMed ID: 29361419
4210  Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Nakamura Y, Chuang VTG, Kinoshita R, Nishida K, Tanaka R, Enoki Y, Ishima Y, Kuniyasu A, Kobashigawa Y, Morioka H, Futaki S, Otagiri M, Maruyama T.  Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.  J Control Release  2018    PubMed ID: 29530390
4478  Omachi K, Kamura M, Teramoto K, Kojima H, Yokota T, Kaseda S, Kuwazuru J, Fukuda R, Koyama K, Matsuyama S, Motomura K, Shuto T, Suico MA, Kai H.  A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.  Cell Chem Biol  2018  25(5):634-643.e4  PubMed ID: 29526710
4479  Takahashi T, Mine Y, Okamoto T.  Intracellular reduction of coenzyme Q homologues with a short isoprenoid side chain induces apoptosis of HeLa cells.  J. Biochem.  2018  163(4):329-339  PubMed ID: 29319808
4480  Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, Tagaya M.  Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3.  J. Lipid Res.  2018  59(5):805-819  PubMed ID: 29549094
4481  Blaise Kimbadi Lombe, Doris Feineis, Virima Mudogo, Reto Brun, Suresh Awale and Gerhard Bringmann  Michellamines A6 and A7, and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese Ancistrocladus liana and their antiausterity activities against pancreatic cancer cells  RSC Adv  2018  8:5243 
9940  Ryosuke Koyama, Wataru Hakamata, Takako Hirano, Toshiyuki Nishio  Identification of Small-Molecule Inhibitors of Human Golgi Mannosidase via a Drug Repositioning Screen  Chem Pharm Bull (Tokyo)  2018  66(6):678-681  PubMed ID: 29540634
14896  Miyanokoshi M, Yokosawa T, Wakasugi K.  Tryptophanyl-tRNA synthetase mediates high-affinity tryptophan uptake into human cells  J Biol Chem  2018  293(22):8428-8438  PubMed ID: 29666190
16293  Arasaki K, Nagashima H, Kurosawa Y, Kimura H, Nishida N, Dohmae N, Yamamoto A, Yanagi S, Wakana Y, Inoue H, Tagaya M.  MAP1B-LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules  EMBO Rep  2018  19(8):e45584  PubMed ID: 29925525
16521  Mitsuhashi H, Ishimaru S, Homma S, Yu B, Honma Y, Beermann ML, Miller JB.  Functional domains of the FSHD-associated DUX4 protein  Biol Open  2018  7(4):bio033977  PubMed ID: 29618456
10129  Hozumi Y, Fujiwara H, Kaneko K, Fujii S, Topham MK, Watanabe M, Goto K.  Diacylglycerol kinase ε localizes to subsurface cisterns of cerebellar Purkinje cells.  Cell Tissue Res.  2017  368:441-458  PubMed ID: 28191598
10236  Sudo K, Niikura K, Iwaki K, Kohyama S, Fujiwara K, Doi N.  Human-derived fusogenic peptides for the intracellular delivery of proteins.  J Control Release  2017  255:1-11  PubMed ID: 28385674
10475  Ono T, Sakamoto C, Nakao M, Saitoh N, Hirano T.  Condensin II plays an essential role in reversible assembly of mitotic chromosomes in situ.  Mol. Biol. Cell  2017  28:2875-2886  PubMed ID: 28835373
10628  Goto M, Osada S, Imagawa M, Nishizuka M.  FAD104, a regulator of adipogenesis, is a novel suppressor of TGF-β-mediated EMT in cervical cancer cells.  Sci Rep  2017  7:16365  PubMed ID: 29180690
10637  Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.  An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.  BMC Nephrol  2017  18:353  PubMed ID: 29202719
10924    Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin  RSC Adv  2017  7, 2392-2402 
10945    Development of a Cartridge-type Cell Culture Device Combined with Poly(N-isopropylacrylamide) Coated Substrates  IEEJ Transactions on Sensors and Micromachines  2017  137, 78-83 
11011  Nagai M, Kato K, Oohara K, Shibata T.  Pick-and-Place Operation of Single Cell Using Optical and Electrical Measurements for Robust Manipulation  Micromachines (Basel)  2017  8(12). pii: E350  PubMed ID: 30400543
4530  Yuki Hiruta, ORCID logo, Yuki Kanda, Naoya Katsuyama and Hideko Kanazawa  Dual temperature- and pH-responsive polymeric micelle for selective and efficient two-step doxorubicin delivery  RSC Adv.  2017  7, 29540-29549 
4546  Arasaki K, Mikami Y, Shames SR, Inoue H, Wakana Y, Tagaya M.  Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17.  Nat Commun  2017  8:15406  PubMed ID: 28504273
12208  Yuki Hiruta, Ryo Nemoto, Hideko Kanazawa  Design and synthesis of temperature-responsive polymer/silica hybrid nanoparticles and application to thermally controlled cellular uptake  Colloids Surf B Biointerfaces  2017  153:2-9  PubMed ID: 28192714
12225  Jian Wang, Eri Ayano, Yoshie Maitani, Hideko Kanazawa  Enhanced cellular uptake and gene silencing activity of siRNA using temperature-responsive polymer-modified liposome  Int J Pharm  2017  523(1):217-228.  PubMed ID: 28330734
14220  Wang J, Ayano E, Maitani Y, Kanazawa H.  Tunable Surface Properties of Temperature-Responsive Polymer-Modified Liposomes Induce Faster Cellular Uptake  ACS Omega  2017  ;2(1):316-325  PubMed ID: 31457232
14226  Hama K, Fujiwara Y, Tabata H, Takahashi H, Yokoyama K.  Comprehensive Quantitation Using Two Stable Isotopically Labeled Species and Direct Detection of N-Acyl Moiety of Sphingomyelin  Lipids  2017  52(9):789-799  PubMed ID: 28770378
14374  Yuichi Miyamoto, Yuri Yamaguchi, Hatsuki Tajima  Effects of Photofrin-mediated photodynamic treatment on sensitivity to cisplatin in HeLa cells and the resistant subline  IFMBE Proceedings  2017  13-15 
14611  Ueda T, Tsubamoto H, Inoue K, Sakata K, Shibahara H, Sonoda T.  Itraconazole Modulates Hedgehog, WNT/β-catenin, as well as Akt Signalling, and Inhibits Proliferation of Cervical Cancer Cells  Anticancer Res  2017  3521-3526  PubMed ID: 28668841
14363  Takiguchi E, Nishimura M, Mineda A, Kawakita T, Abe A, Irahara M.  Growth inhibitory effect of the Src inhibitor dasatinib in combination with anticancer agents on uterine cervical adenocarcinoma cells  Exp Ther Med  2017  14(5):4293-4299  PubMed ID: 29067110
14661  Naotsugu Nagasawa, Atsushi Kimura, Akira Idesaki, Naoto Yamada, Masashi Koka, Takahiro Satoh, Yasuyuki Ishii, Mitsumasa Taguchi  Microfabrication of biocompatible hydrogels by proton beam writing  Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms  2017  409:102-106 
14676  Suzuki T, Imada T, Komatsu Y, Kamiya H.  Comparison of DNA fragments as donor DNAs upon sequence conversion of cleaved target DNA  Nucleosides Nucleotides Nucleic Acids  2017  36(6):428-434  PubMed ID: 28486036
14725  Minegishi S, Yumura A, Miyoshi H, Negi S, Taketani S, Motterlini R, Foresti R, Kano K, Kitagishi H.  Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes  J Am Chem Soc  2017  139(16):5984-5991  PubMed ID: 28388069
14757  Yamauchi I, Sakane Y, Fukuda Y, Fujii T, Taura D, Hirata M, Hirota K, Ueda Y, Kanai Y, Yamashita Y, Kondo E, Sone M, Yasoda A, Inagaki N.  Clinical Features of Nivolumab-Induced Thyroiditis: A Case Series Study  Thyroid  2017  27(7):894-901  PubMed ID: 28537531
14762  Nakagawa T, Suzuki-Nakagawa C, Watanabe A, Asami E, Matsumoto M, Nakano M, Ebihara A, Uddin MN, Suzuki F.  Site-1 protease is required for the generation of soluble (pro)renin receptor  J Biochem  2017  161(4):369-379  PubMed ID: 28013223
14769  Motohiro Tagaya, Shigeaki Abe, Satoshi Motozuka, Kota Shiba, Taro Takemura, Ikuo Hayashi, Yoshimitsu Sakaguchi  Surface-engineered mesoporous silica particles with luminescent, cytocompatible and targeting properties for cancer cell imaging  RSC Advances  2017  7:13643-13652 
16616  Machitani M, Sakurai F, Wakabayashi K, Tachibana M, Fujiwara T, Mizuguchi H.  Enhanced Oncolytic Activities of the Telomerase-Specific Replication-Competent Adenovirus Expressing Short-Hairpin RNA against Dicer  Mol Cancer Ther  2017  16(1):251-259  PubMed ID: 27760834
16617  Konno H, Onuma T, Nitanai I, Wakabayashi M, Yano S, Teruya K, Akaji K.  Synthesis and evaluation of phenylisoserine derivatives for the SARS-CoV 3CL protease inhibitor  Bioorg Med Chem Lett  2017  27(12):2746-2751  PubMed ID: 28454669
16628  Machitani M, Sakurai F, Wakabayashi K, Nakatani K, Tachibana M, Mizuguchi H.  MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2  J Virol  2017  91(12):e00159-17  PubMed ID: 28356525
7046  Bonneau B, Ando H, Kawaai K, Hirose M, Takahashi-Iwanaga H, Mikoshiba K.  IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact.  Elife  2016  5:  PubMed ID: 27995898
7048  Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.  Five colour variants of bright luminescent protein for real-time multicolour bioimaging.  Nat Commun  2016  7:13718  PubMed ID: 27966527
7058  Ueyama T, Ninoyu Y, Nishio SY, Miyoshi T, Torii H, Nishimura K, Sugahara K, Sakata H, Thumkeo D, Sakaguchi H, Watanabe N, Usami SI, Saito N, Kitajiri SI.  Constitutive activation of DIA1 (DIAPH1) via C-terminal truncation causes human sensorineural hearing loss.  EMBO Mol Med  2016  8:1310-1324  PubMed ID: 27707755
7060  Kanda S, Yanagitani K, Yokota Y, Esaki Y, Kohno K.  Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E5886-E5895  PubMed ID: 27651490
7090  Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, Kataoka K, Saito T, Chung UI, Ohba S.  Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.  Sci Rep  2016  6:18743  PubMed ID: 26728350
7092  M Khanmohammadi, S Sakai, T Ashida, M Taya  Production of hyaluronic-acid-based cell-enclosing microparticles and microcapsules via enzymatic reaction using a microfluidic system.  J Applied Polymer Science  2016  133:43107 
9802  Hane M, Kitajima K, Sato C.  Effects of intronic single nucleotide polymorphisms (iSNPs) of a polysialyltransferase, ST8SIA2 gene found in psychiatric disorders on its gene products.  Biochem. Biophys. Res. Commun.  2016  478:1123-9  PubMed ID: 27565727
10018  Niwa F, Sakuragi S, Kobayashi A, Takagi S, Oda Y, Bannai H, Mikoshiba K.  Dissection of local Ca(2+) signals inside cytosol by ER-targeted Ca(2+) indicator.  Biochem. Biophys. Res. Commun.  2016  479:67-73  PubMed ID: 27616195
10024  Matsumura K, Nakata S, Taniguchi K, Ii H, Ashihara E, Kageyama S, Kawauchi A, Yoshiki T.  Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation.  BMC Cancer  2016  16:748  PubMed ID: 27658708
10913    Clinical potential of DAC-70 sol  Integr Mol Med  2016  3: 645-648 
9941  Kazuki Miura, Wataru Hakamata, Ayako Tanaka, Takako Hirano, Toshiyuki Nishio  Discovery of Human Golgi β-Galactosidase With No Identified Glycosidase Using a QMC Substrate Design Platform for Exo-Glycosidase  Bioorg Med Chem  2016  24(6):1369-75  PubMed ID: 26875935
12668  Suzuki T, Imada T, Nishigaki N, Kobayashi M, Matsuoka I, Kamiya H.  Cleavage of Target DNA Promotes Sequence Conversion with a Tailed Duplex  Biol Pharm Bull  2016  39(8):1392-5  PubMed ID: 27476948
12689  Yoshida M, Onda Y, Masuda Y, Doi T.  Potent oxazoline analog of apratoxin C: Synthesis, biological evaluation, and conformational analysis  Biopolymers  2016  106(4):404-14  PubMed ID: 26584466
12872  Niikura K, Horisawa K, Doi N.  Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation  J Biochem   2016  159(1):123-32.  PubMed ID: 26338729
6909  Fujita S, Onuki-Nagasaki R, Ikuta K, Hara Y.  A simple method for producing multiple copies of controlled release small molecule microarrays for cell-based screening  Biofabrication  2016  9(1):011001  PubMed ID: 27917820
12853  Henmi Y, Oe N, Kono N, Taguchi T, Takei K, Tanabe K.  Phosphatidic acid induces EHD3-containing membrane tubulation and is required for receptor recycling  Exp Cell Res  2016  342(1):1-10  PubMed ID: 26896729
14188  Daisuke Takahashi, Takashi Nagao, Shota Sotokawa, Kazunobu Toshima  Target-selective photo-degradation of a sialyl Lewis a (sLea) conjugate and photo-cytotoxicity against sLea positive cancer cells using an anthraquinone-antibody hybrid  MedChemComm  2016  7:1224-1228 
7100  Bannai H, Niwa F, Sherwood MW, Shrivastava AN, Arizono M, Miyamoto A, Sugiura K, Levi S, Triller A, Mikoshiba K.  Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium.  Cell Rep  2015  13:2768-80  PubMed ID: 26711343
7154  Abe N, Matsumoto K, Nishihara M, Nakano Y, Shibata A, Maruyama H, Shuto S, Matsuda A, Yoshida M, Ito Y, Abe H.  Rolling Circle Translation of Circular RNA in Living Human Cells.  Sci Rep  2015  5:16435  PubMed ID: 26553571
7339  Kobayashi S, Koujin T, Kojidani T, Osakada H, Mori C, Hiraoka Y, Haraguchi T.  BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy.  Proc. Natl. Acad. Sci. U.S.A.  2015  112:7027-32  PubMed ID: 25991860
7454  Takeda I, Kawanabe M, Kaneko A.  Autonomous patterning of cells on microstructured fine particles.  Mater Sci Eng C Mater Biol Appl  2015  50:173-8  PubMed ID: 25746259
5372  Nakajima Y, Kanno T, Nagaya T, Kuribayashi K, Nakano T, Gotoh A, Nishizaki T.  Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.  Cell Physiol Biochem  2015  35(1):51-60  PubMed ID: 25547995
6612  Okuma T, Hirata M, Yano F, Mori D, Kawaguchi H, Chung UI, Tanaka S, Saito T.  Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins.  Biomed Res  2015  36(1):21-9  PubMed ID: 25749148
9955  Wataru Hakamata, Kazuki Miura, Takako Hirano, Toshiyuki Nishio  Identification of a Novel Glycan Processing Enzyme With Exo-Acting β-Allosidase Activity in the Golgi Apparatus Using a New Platform for the Synthesis of Fluorescent Substrates  Bioorg Med Chem  2015  23(1):73-9  PubMed ID: 25497961
12243  Takuma Nozoe, Shigemi Goda, Roman Selyanchyn, Tao Wang, Kohji Nakazawa, Takeshi Hirano, Hidetaka Matsui, Seung-Woo Lee  In vitro detection of small molecule metabolites excreted from cancer cells using a Tenax TA thin-film microextraction device  J Chromatogr B Analyt Technol Biomed Life Sci  2015  991:99-107.  PubMed ID: 25932789
12244  Shigeru Negi, Yuka Terada, Misato Suzuyama, Haruka Matsumoto, Akino Honbo, Yoko Amagase, Yumiko Mizukawa, Akiko Kiriyama, Katsumi Iga, Tetsuro Urushidaini, Yukio Sugiura  Intrinsic cell permeability of the GAGA zinc finger protein into HeLa cells  Biochem Biophys Res Commun  2015  464(4):1034-1039  PubMed ID: 26187668
12253  Kazuaki Nagayama, Yumi Hamaji, Yuji Sato, Takeo Matsumoto  Mechanical trapping of the nucleus on micropillared surfaces inhibits the proliferation of vascular smooth muscle cells but not cervical cancer HeLa cells  J Biomech  2015  48(10):1796-803  PubMed ID: 26054426
12254  Keisuke Niikura, Kenichi Horisawa, Nobuhide Doi  A fusogenic peptide from a sea urchin fertilization protein promotes intracellular delivery of biomacromolecules by facilitating endosomal escape  J Control Release  2015  212:85-93  PubMed ID: 26091921
14968  Ishigaki Y, Nakamura Y, Tatsuno T, Ma S, Tomosugi N.  Phosphorylation status of human RNA-binding protein 8A in cells and its inhibitory regulation by Magoh  Exp Biol Med (Maywood)   2015  240(4):438-45  PubMed ID: 25349214
14982  Miyagawa-Yamaguchi A, Kotani N, Honke K.  Each GPI-anchored protein species forms a specific lipid raft depending on its GPI attachment signa  Glycoconj J  2015  32(7):531-40  PubMed ID: 25948169
14999  Kondo T, Okada M, Kunihiro K, Takahashi M, Yaoita Y, Hosoya H, Hamao K.  Characterization of myosin II regulatory light chain isoforms in HeLa cells  Cytoskeleton (Hoboken)  2015  72(12):609-20  PubMed ID: 26663899
15132  Iwamoto Y, Kodera M, Hitomi Y.  Uncaging a catalytic hydrogen peroxide generator through the photo-induced release of nitric oxide from a {MnNO}(6) complex  Chem Commun (Camb)  2015  51(46):9539-42  PubMed ID: 25967395
15160  Yuki Hiruta, Takaaki Funatsu, Minami Matsuura, Jian Wang, Eri Ayano, Hideko Kanazawa  pH/temperature-responsive fluorescence polymer probe with pH-controlled cellular uptake  Sensors and Actuators B: Chemical  2015  207:724-731 
15194  Ahmed F. M. El-Mahdy, Takayuki Shibata, Tsutomu Kabashima, Qinchang Zhu, Masaaki Kai  Delivery of siRNA using siRNA/cationic vector complexes encapsulated in dendrimer-like polymeric DNAs  RSC Advances  2015  5:32775-32785 
15209  Kasai A, Arafuka S, Koshiba N, Takahashi D, Toshima K.  Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells  Org Biomol Chem  2015  13(42):10556-68  PubMed ID: 26340595
15239  Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I.  Hydroxylated fullerene: a potential antiinflammatory and antioxidant agent for preventing mouse preterm birth  Am J Obstet Gynecol  2015  213(5):708.e1-9  PubMed ID: 26196453
6814  Liew YJ, Soh WT, Jiemy WF, Hwang JS.  Mutagenesis and functional analysis of the pore-forming toxin HALT-1 from Hydra magnipapillata  Toxins (Basel)  2015  7(2):407-22  PubMed ID: 25654788
13624  Tamura M, Yanagawa F, Sugiura S, Takagi T, Sumaru K, Kanamori T.  Click-crosslinkable and photodegradable gelatin hydrogels for cytocompatible optical cell manipulation in natural environment  Sci Rep  2015  5:15060  PubMed ID: 26450015
4056  Xu B, Ju Y, Cui Y, Song G, Iwase Y, Hosoi A, Morita Y.  tLyP-1-conjugated Au-nanorod@SiO(2) core-shell nanoparticles for tumor-targeted drug delivery and photothermal therapy.  Langmuir  2014  30:7789-97  PubMed ID: 24921672
5643  Ishikawa K, Ishikawa A, Shoji Y, Imai T.  A genotoxic stress-responsive miRNA, miR-574-3p, delays cell growth by suppressing the enhancer of rudimentary homolog gene in vitro.  Int J Mol Sci  2014  15(2):2971-90  PubMed ID: 24566139
6331  Miura Y, Sato T, Sakurai Y, Sakai R, Hiraoka W, Endo T.  Hyper-O-GlcNAcylation inhibits the induction of heat shock protein 70 (Hsp 70) by sodium arsenite in HeLa cells.  Biol Pharm Bull  2014  37(8):1308-14  PubMed ID: 25087952
9979  Wataru Hakamata, Saori Tamura, Takako Hirano, Toshiyuki Nishio  Multicolor Imaging of Endoplasmic Reticulum-Located Esterase as a Prodrug Activation Enzyme  ACS Med Chem Lett .  2014  5(4):321-5  PubMed ID: 24900834
15861  Junedi S, Yasuhara K, Nagao S, Kikuchi J, Hirota S.  Morphological change of cell membrane by interaction with domain-swapped cytochrome c oligomers  Chembiochem  2014  15(4):517-21  PubMed ID: 24449526
15862  Kuroda A, Ishigaki Y, Nilsson M, Sato K, Sato K.  Microfluidics-based in situ padlock/rolling circle amplification system for counting single DNA molecules in a cell  Anal Sci  2014  30(12):1107-12  PubMed ID: 25492458
15865  Yutaka Hitomi, Toshiyuki Takeyasu, Masahito Kodera  Development of Green-Emitting Iron Complex-Based Fluorescent Probes for Intracellular Hydrogen Peroxide Imaging  Bulletin of the Chemical Society of Japan  2014  87:819-824 
15900  Hirofumi Shintaku, Kazumi Hakamada, Hiroshi Fujimoto, Takeshi Nagata, Jun Miyake, Satoyuki Kawano  Measurement of local electric field in microdevices for low-voltage electroporation of adherent cells  Microsystem Technologies  2014  20:303-313 
15901  Kadonosono T, Yabe E, Furuta T, Yamano A, Tsubaki T, Sekine T, Kuchimaru T, Sakurai M, Kizaka-Kondoh S.  A fluorescent protein scaffold for presenting structurally constrained peptides provides an effective screening system to identify high affinity target-binding peptides  PLoS One  2014  ;9(8):e103397.  PubMed ID: 25084350
3914  Kazuhiro Hiyama, Hirofumi Matsui, Masato Tamura, Osamu Shimokawa, Mariko Hiyama, Tsuyoshi Kaneko, Yumiko Nagano, Ichinosuke Hyodo, Junko Tanaka, Yoshihiro Miwa, Tetsuo Ogawa, Takeo Nakanishi and Ikumi Tamai  Cancer cells uptake porphyrins via heme carrier protein 1  Journal of Porphyrins and Phthalocyanines  2013  17:36-43 
6565  Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H.  β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.  Arthritis Rheum  2013  65(2):429-35  PubMed ID: 23124878
15769  Tanaka T, Okada M, Hozumi Y, Tachibana K, Kitanaka C, Hamamoto Y, Martelli AM, Topham MK, Iino M, Goto K.  Cytoplasmic localization of DGKζ exerts a protective effect against p53-mediated cytotoxicity  J Cell Sci  2013  126(Pt 13):2785-97  PubMed ID: 23606744
15786  Ono T, Yamashita D, Hirano T.  Condensin II initiates sister chromatid resolution during S phase  J Cell Biol  2013  200(4):429-41  PubMed ID: 23401001
15788  Kajimoto T, Okada T, Miya S, Zhang L, Nakamura S.  Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes  Nat Commun  2013  4:2712  PubMed ID: 24231649
15922  Fujitani N, Furukawa J, Araki K, Fujioka T, Takegawa Y, Piao J, Nishioka T, Tamura T, Nikaido T, Ito M, Nakamura Y, Shinohara Y.  Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers  Proc Natl Acad Sci U S A   2013  110(6):2105-10  PubMed ID: 23345451
15938  Himeda T, Hosomi T, Okuwa T, Muraki Y, Ohara Y.  Saffold virus type 3 (SAFV-3) persists in HeLa cells  PLoS One  2013  e53194  PubMed ID: 23308162
15939  Uchida K, Nakahira K, Mimura K, Shimizu T, De Seta F, Wakimoto T, Kawai Y, Nomiyama M, Kuwano K, Guaschino S, Yanagihara I.  Effects of Ureaplasma parvum lipoprotein multiple-banded antigen on pregnancy outcome in mice  J Reprod Immunol  2013  100(2):118-27  PubMed ID: 24238827
15943  Tsuyoshi KIMURA, Yukie KANDA, Asami SANO, Kwangwoo NAM, Yoshihiro SASAKI, Kazunari AKIYOSHI, Toshiya FUJISATO, Akio KISHIDA  High Hydrostatic Pressurized Lipoplex Enhances Transfection Efficiency In Vitro  Advanced Biomedical Engineering  2013  2:80-83 
15945  Ayaki Miyama, Masumi Yamada, Sari Sugaya, Minoru Seki  A droplet-based microfluidic process to produce yarn-ball-shaped hydrogel microbeads  RSC Advances  2013  3:12299 
15971  Satoshi Fujita, Reiko Onuki-Nagasaki, Junji Fukuda, Junko Enomoto, Suichi Yamaguchi, Masato Miyake  Development of super-dense transfected cell microarrays generated by piezoelectric inkjet printing  Lab Chip  2013  13:77-80 
7614  Kondo T, Isoda R, Uchimura T, Sugiyama M, Hamao K, Hosoya H.  Diphosphorylated but not monophosphorylated myosin II regulatory light chain localizes to the midzone without its heavy chain during cytokinesis.  Biochem. Biophys. Res. Commun.  2012  417:686-91  PubMed ID: 22166199
7617  Satow R, Shitashige M, Jigami T, Fukami K, Honda K, Kitabayashi I, Yamada T.  β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.  Gastroenterology  2012  142:572-81  PubMed ID: 22155184
6096  Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, Kayamori K, Katsube K, Yamaguchi A.  Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms.  Lab Invest  2012  92(5):688-702  PubMed ID: 22330335
6318  Miura Y, Sakurai Y, Endo T.  O-GlcNAc modification affects the ATM-mediated DNA damage response.  Biochim Biophys Acta  2012  1820(10):1678-85  PubMed ID: 22759405
6433  Hiratochi M, Tatani K, Shimizu K, Kuramochi Y, Kikuchi N, Kamada N, Itoh F, Isaji M.  Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides.  Eur J Pharmacol  2012  690(1-3):183-91  PubMed ID: 22709993
9161  Takahiro Seki, Ken-ich Yoshino, Shigeru Tanaka, Eisuke Dohi, Tomoya Onji, Kazuhiro Yamamoto, Izumi Hide, Henry L Paulson, Naoaki Saito, Norio Sakai  Establishment of a Novel Fluorescence-Based Method to Evaluate Chaperone-Mediated Autophagy in a Single Neuron  PLoS One   2012  7 (2), e31232  PubMed ID: 22363588
14005  Sato Y, Hatakeyama H, Sakurai Y, Hyodo M, Akita H, Harashima H.  A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo  J Control Release   2012  163(3):267-76  PubMed ID: 23000694
15735  Kondo T, Itakura S, Hamao K, Hosoya H.  Phosphorylation of myosin II regulatory light chain controls its accumulation, not that of actin, at the contractile ring in HeLa cells  Exp Cell Res  2012  318(8):915-24  PubMed ID: 22374324
15738  Kawai S, Amano A.  BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex  J Cell Biol  2012  197(2):201-8  PubMed ID: 22492723
15748  Sugimoto M, Watanabe T, Sugimoto Y.  The molecular effects of a polymorphism in the 5'UTR of solute carrier family 44, member 5 that is associated with birth weight in Holsteins  PLoS One  2012  7(7):e41267  PubMed ID: 22815983
15750  Tatsuya Nishihara, Hiroshi Nonaka, Tatsuya Naganuma, Kazuhiro Ichikawa, Shinsuke Sando  Mouse lactate dehydrogenase X: A promising magnetic resonance reporter protein using hyperpolarized pyruvic acid derivative Y  Chem. Sci  2012  3:800-806 
15757  Niwa F, Bannai H, Arizono M, Fukatsu K, Triller A, Mikoshiba K.  Gephyrin-independent GABA(A)R mobility and clustering during plasticity  PLoS One  2012  7(4):e36148  PubMed ID: 22563445
15944  Motohiro Tagaya, Nobutaka Hanagata, Toshiyuki Ikoma, Takaomi Kobayashi, Kota Shiba, Tomohiko Yoshioka, Junzo Tnaka  Cytotoxicity and Cancer Detection Ability of the Luminescent Nanoporous Silica Spheres Immobilized with Folic Acid Derivative  Key Engineering Materials  2012  529-530:630-635 
15966  Masumi Yamada, Sari Sugaya, Yoji Naganuma, Minoru Seki  Microfluidic synthesis of chemically and physically anisotropic hydrogel microfibers for guided cell growth and networking  Soft Matter  2012  8:3122 
15970  Md. Shariful Islam, Yoshihumi Kusumoto, Md. Abdulla-Al-Mamun, Yuji Horie, Hirotaka Manaka  Enhancement of cumulative photoirradiated and ac magnetic-field induced cancer (HeLa) cell killing efficacy of mixed α and γ-Fe2O3 magnetic nanoparticles  New Journal of Chemistry  2012  36:1201 
15972  Masahito BAN, Yuuya KOGI, Fusako SASAKI  Cytotoxicity of Photosensitizing Crystalline C60 Particles Formed by Ink-jet Method  Journal of the Imaging Society of Japan  2012  51:496-500 
15974  Burroughs AM, Kawano M, Ando Y, Daub CO, Hayashizaki Y.  pre-miRNA profiles obtained through application of locked nucleic acids and deep sequencing reveals complex 5'/3' arm variation including concomitant cleavage and polyuridylation patterns  Nucleic Acids Res  2012  40(4):1424-37  PubMed ID: 22058130
15975  Taira N, Mimoto R, Kurata M, Yamaguchi T, Kitagawa M, Miki Y, Yoshida K.  DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells  J Clin Invest  2012  122(3):859-72  PubMed ID: 22307329
15976  Takuma TSUJI, and Jiro USUKURA  Assessment on a Biological Toxicity Caused by Single-walled Carbon Nanotubes  Nano Biomedicine  2012  4:125-132 
15977  Sato H, Yamada R, Yanagihara M, Okuzawa H, Iwata H, Kurosawa A, Ichinomiya S, Suzuki R, Okabe H, Yano T, Kumamoto T, Suzuki N, Ishikawa T, Ueno K.  New 2-aryl-1,4-naphthoquinone-1-oxime methyl ether compound induces microtubule depolymerization and subsequent apoptosis  J Pharmacol Sci  2012  118(4):467-78  PubMed ID: 22447301
15978  Yuma Yamada, Eriko Kawamura, Hideyoshi Harashima  Mitochondrial-targeted DNA delivery using a DF-MITO-Porter, an innovative nano carrier with cytoplasmic and mitochondrial fusogenic envelopes  Journal of Nanoparticle Research  2012  14 
16311  Md. Shariful Islam, Yoshihumi Kusumoto, Md. Abdulla-Al-Mamun, Yuji Horie  Synergistic Cell Killing by Magnetic and Photoirradiation Effects of Neck-structured α-Fe2O3against Cancer (HeLa) Cells  Chemistry Letters  2012  40:773-775 
16569  Ooe H, Chen Q, Kon J, Sasaki K, Miyoshi H, Ichinohe N, Tanimizu N, Mitaka T.  Proliferation of rat small hepatocytes requires follistatin expression  J Cell Physiol  2012  227(6):2363-70  PubMed ID: 21826650
16570  Karasugi K, Kitagishi H, Kano K.  Modification of a dioxygen carrier, hemoCD, with PEGylated dendrons for extension of circulation time in the bloodstream  Bioconjug Chem  2012  23(12):2365-76  PubMed ID: 23136812
16577  Hirano Y, Hizume K, Kimura H, Takeyasu K, Haraguchi T, Hiraoka Y.  Lamin B receptor recognizes specific modifications of histone H4 in heterochromatin formation  J Biol Chem  2012  287(51):42654-63  PubMed ID: 23100253
16578  Yoshikawa Y, Ochiai K, Morimatsu M, Suzuki Y, Wada S, Taoda T, Iwai S, Chikazawa S, Orino K, Watanabe K.  Effects of the missense mutations in canine BRCA2 on BRC repeat 3 functions and comparative analyses between canine and human BRC repeat 3  PLoS One  2012  7(10):e45833  PubMed ID: 23071527
16579  Bae JY, Mie M, Kobatake E.  Targeted gene delivery via PEI complexed with an antibody  Appl Biochem Biotechnol  2012  168(8):2184-90  PubMed ID: 23054824
16580  Shiheido H, Naito Y, Kimura H, Genma H, Takashima H, Tokunaga M, Ono T, Hirano T, Du W, Yamada T, Doi N, Iijima S, Hattori Y, Yanagawa H.  An anilinoquinazoline derivative inhibits tumor growth through interaction with hCAP-G2, a subunit of condensin II  PLoS One  2012  7(9):e44889  PubMed ID: 23028663
16581  Kubo T, Yanagihara K, Sato Y, Morita Y, Seyama T.  Enhancement of gene silencing effect and membrane permeability by Peptide-conjugated 27-nucleotide small interfering RNA  Molecules  2012  17(9):11089-102  PubMed ID: 22983148
16582  Ogasawara J, Sakurai T, Kizaki T, Ishibashi Y, Izawa T, Sumitani Y, Ishida H, Radak Z, Haga S, Ohno H.  Higher levels of ATGL are associated with exercise-induced enhancement of lipolysis in rat epididymal adipocytes  PLoS One  2012  7(7):e40876.  PubMed ID: 22815850
16583  Shiheido H, Terada F, Tabata N, Hayakawa I, Matsumura N, Takashima H, Ogawa Y, Du W, Yamada T, Shoji M, Sugai T, Doi N, Iijima S, Hattori Y, Yanagawa H.  A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma  PLoS One  2012  7(6):e38878.  PubMed ID: 22761710
16584  Yamaguchi M, Ito A, Okamoto N, Kawabe Y, Kamihira M.  Heat-inducible transgene expression system incorporating a positive feedback loop of transcriptional amplification for hyperthermia-induced gene therapy  J Biosci Bioeng  2012  114(4):460-5  PubMed ID: 22658541
16585  Sakai S, Inagaki H, Liu Y, Matsuyama T, Kihara T, Miyake J, Kawakami K, Taya M.  Rapidly serum-degradable hydrogel templating fabrication of spherical tissues and curved tubular structures  Biotechnol Bioeng  2012  109(11):2911-9  PubMed ID: 22566297
16586  Xu L, Li X, Takemura T, Hanagata N, Wu G, Chou LL.  Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel  J Nanobiotechnology  2012  10:16  PubMed ID: 22548743
16587  Toyama K, Yamada M, Seki M.  Isolation of cell nuclei in microchannels by short-term chemical treatment via two-step carrier medium exchange  Biomed Microdevices  2012  14(4):751-7  PubMed ID: 22544390
16588  Kondo Y, Ishitsuka Y, Kadowaki D, Kuroda M, Tanaka Y, Nagatome M, Irikura M, Hirata S, Sato K, Maruyama T, Hamasaki N, Irie T.  Phosphoenolpyruvic acid, an intermediary metabolite of glycolysis, as a potential cytoprotectant and anti-oxidant in HeLa cells  Biol Pharm Bull  2012  35(4):606-11  PubMed ID: 22466568
16589  Nakase I, Konishi Y, Ueda M, Saji H, Futaki S.  Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo  J Control Release  2012  159(2):181-8  PubMed ID: 22285548
16590  Sakai S, Inamoto K, Liu Y, Tanaka S, Arii S, Taya M.  Multicellular tumor spheroid formation in duplex microcapsules for analysis of chemosensitivity  Cancer Sci  2012  103(3):549-54  PubMed ID: 22168771
16591  Yamada Y, Harashima H.  Delivery of bioactive molecules to the mitochondrial genome using a membrane-fusing, liposome-based carrier, DF-MITO-Porter  Biomaterials  2012  33(5):1589-95  PubMed ID: 22105068
16592  Li Y, Mitsuhashi S, Ikejo M, Miura N, Kawamura T, Hamakubo T, Ubukata M.  Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1  Biosci Biotechnol Biochem  2012  76(3):486-94  PubMed ID: 10.1271/bbb.1107722451389
16593  Takahashi M, Elbarbary RA, Abe M, Sato M, Yoshida T, Yamada Y, Tamura M, Nashimoto M.  Elimination of specific miRNAs by naked 14-nt sgRNAs  PLoS One  2012  7(6):e38496  PubMed ID: 22675569
7662  Byambaa B, Konno T, Ishihara K.  Cell adhesion control on photoreactive phospholipid polymer surfaces.  Colloids Surf B Biointerfaces  2011  99:1-6  PubMed ID: 21982212
7809  Ochiai K, Yoshikawa Y, Yoshimatsu K, Oonuma T, Tomioka Y, Takeda E, Arikawa J, Mominoki K, Omi T, Hashizume K, Morimatsu M.  Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51.  FEBS Lett.  2011  585:1771-7  PubMed ID: 21601571
7923  Okano K, Yu D, Matsui A, Maezawa Y, Hosokawa Y, Kira A, Matsubara M, Liau I, Tsubokawa H, Masuhara H.  Induction of cell-cell connections by using in situ laser lithography on a perfluoroalkyl-coated cultivation platform.  Chembiochem  2011  12:795-801  PubMed ID: 21341350
7953  Watanabe S, Wakasugi K.  Module M1 of zebrafish neuroglobin acts as a structural and functional protein building block for a cell-membrane-penetrating activity.  PLoS ONE  2011  6:e16808  PubMed ID: 21304818
7983  Kondo T, Hamao K, Kamijo K, Kimura H, Morita M, Takahashi M, Hosoya H.  Enhancement of myosin II/actin turnover at the contractile ring induces slower furrowing in dividing HeLa cells.  Biochem. J.  2011  435:569-76  PubMed ID: 21231914
7995  Kaneko S, Nakayama H, Yoshino Y, Fushimi D, Yamaguchi K, Horiike Y, Nakanishi J.  Photocontrol of cell adhesion on amino-bearing surfaces by reversible conjugation of poly(ethylene glycol) via a photocleavable linker.  Phys Chem Chem Phys  2011  13:4051-9  PubMed ID: 21225032
8016  Li G, Kawashima H, Ogose A, Ariizumi T, Xu Y, Hotta T, Urata Y, Fujiwara T, Endo N.  Efficient virotherapy for osteosarcoma by telomerase-specific oncolytic adenovirus.  J. Cancer Res. Clin. Oncol.  2011  137:1037-51  PubMed ID: 21193997
8025  Furukawa R, Yamada Y, Takenaga M, Igarashi R, Harashima H.  Octaarginine-modified liposomes enhance the anti-oxidant effect of Lecithinized superoxide dismutase by increasing its cellular uptake.  Biochem. Biophys. Res. Commun.  2011  404:796-801  PubMed ID: 21168389
3711  Fukushima T, Kawaguchi M, Yamasaki M, Tanaka H, Yorita K, Kataoka H.  Hepatocyte growth factor activator inhibitor type 1 suppresses metastatic pulmonary colonization of pancreatic carcinoma cells.  Cancer Sci  2011  102(2):407-13  PubMed ID: 21166957
6391  Fujitani N, Takegawa Y, Ishibashi Y, Araki K, Furukawa J, Mitsutake S, Igarashi Y, Ito M, Shinohara Y.  Qualitative and quantitative cellular glycomics of glycosphingolipids based on rhodococcal endoglycosylceramidase-assisted glycan cleavage, glycoblotting-assisted sample preparation, and matrix-assisted laser desorption ionization tandem time-of-flight mass spectrometry analysis.  J Biol Chem  2011  286(48):41669-79  PubMed ID: 21965662
4886  Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N.  Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways.  Development  2011  138(8):1507-19  PubMed ID: 21367821
8358  Zhang W, Tsurushima H, Oyane A, Yazaki Y, Sogo Y, Ito A, Matsumura A.  BMP-2 gene-fibronectin-apatite composite layer enhances bone formation.  J Biomed Sci  2011  18:62  PubMed ID: 21859498
12233  Yuma Yamada, Ryo Furukawa, Yukari Yasuzaki, Hideyoshi Harashima  Dual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery  Mol Ther  2011  19(8):1449-56  PubMed ID: 21694702
15718  Kawatani M, Takayama H, Muroi M, Kimura S, Maekawa T, Osada H.  Identification of a small-molecule inhibitor of DNA topoisomerase II by proteomic profiling  Chem Biol  2011  18(6):743-51  PubMed ID: 21700210
16169  Md. Shariful Islam, Yoshihumi Kusumoto, Md. Abdulla-Al-Mamun, Yuji Horie  Photocatalytic and AC magnetic-field induced enhanced cytotoxicity of Fe3O4–TiO2 core-shell nanocomposites against HeLa cells  Catalysis Communications  2011  16:39-44 
16312  Auer S, Hable V, Greubel C, Drexler GA, Schmid TE, Belka C, Dollinger G, Friedl AA.  Survival of tumor cells after proton irradiation with ultra-high dose rates  Radiat Oncol  2011  6:139  PubMed ID: 22008289
16317  Ishikawa T, Saito T, Kurosawa A, Watanabe T, Maruyama S, Ichikawa Y, Yamada R, Okuzawa H, Sato H, Ueno K.  2-Aryl-1,4-naphthoquinone-1-oxime methyl ethers: their cytotoxic activity  Chem Pharm Bull (Tokyo)  2011  59(4):472-5  PubMed ID: 21467676
16318  Toshiro Kibe, Michiko Kishida, Masayuki Kamino, Mikio Iijima, Lin Chen, Mika Habu, Akihiko Miyawaki, Hiroshi Hijioka, Norifumi Nakamura, Tohru Kiyono, Shosei Kishida  Immortalization and characterization of normal oral epithelial cells without using HPV and SV40 genes  Oral Science International  2011  8:20-28 
16564  Ishibashi O, Ali MM, Luo SS, Ohba T, Katabuchi H, Takeshita T, Takizawa T.  Short RNA duplexes elicit RIG-I-mediated apoptosis in a cell type- and length-dependent manner  Sci Signal  2011  4(198):ra74.  PubMed ID: 22067459
16565  Kaida A, Sawai N, Sakaguchi K, Miura M.  Fluorescence kinetics in HeLa cells after treatment with cell cycle arrest inducers visualized with Fucci (fluorescent ubiquitination-based cell cycle indicator)  Cell Biol Int  2011  35(4):359-63  PubMed ID: 21231917
16566  Yamasuji M, Shibata T, Kabashima T, Kai M.  Chemiluminescence detection of telomere DNA in human cells on a membrane by using fluorescein-5-isothiocyanate-labeled primers  Anal Biochem  2011  413(1):50-4  PubMed ID: 21300019
16567  Sakurai Y, Hatakeyama H, Sato Y, Akita H, Takayama K, Kobayashi S, Futaki S, Harashima H.  Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA  Biomaterials  2011  32(24):5733-42  PubMed ID: 21605898
16568  Shaheen SM, Akita H, Yamashita A, Katoono R, Yui N, Biju V, Ishikawa M, Harashima H.  Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET  Nucleic Acids Res  2011  39(7):e48  PubMed ID: 21288880
8341  Hakoda M, Wakizaka Y, Hirota Y.  Separation of viable and nonviable animal cell using dielectrophoretic filter.  Biotechnol. Prog.  2010  26:1061-7  PubMed ID: 20205163
6010  Shinji Sugiura, Koji Hattori and Toshiyuki Kanamori  Integrated Perfusion Culture Microchamber Array Chip for High-Throughput Drug Dose Response Assay  ECS Trans  2010  33(8):197-207 
6119  Okahashi N, Nakata M, Sakurai A, Terao Y, Hoshino T, Yamaguchi M, Isoda R, Sumitomo T, Nakano K, Kawabata S, Ooshima T.  Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion.  Biochem Biophys Res Commun  2010  391(2):1192-6  PubMed ID: 20004645
6305  Aoki S, Honma M, Kariya Y, Nakamichi Y, Ninomiya T, Takahashi N, Udagawa N, Suzuki H.  Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis.  J Bone Miner Res  2010  25(9):1907-2  PubMed ID: 20560139
4665  Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H.  Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.  Nat Med  2010  16(6):678-86  PubMed ID: 20495570
12759  Maruichi T, Fukami T, Nakajima M, Yokoi T.  Transcriptional regulation of human carboxylesterase 1A1 by nuclear factor-erythroid 2 related factor 2 (Nrf2)  Biochem Pharmacol  2010  79(2):288-95  PubMed ID: 19715681
12760  Ando H, Horibata Y, Yamashita S, Oyama T, Sugimoto H.  Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro  Biochim Biophys Acta  2010  1801(4):487-95  PubMed ID: 20045741
15692  Yoshikawa F, Banno Y, Otani Y, Yamaguchi Y, Nagakura-Takagi Y, Morita N, Sato Y, Saruta C, Nishibe H, Sadakata T, Shinoda Y, Hayashi K, Mishima Y, Baba H, Furuichi T.  Phospholipase D family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia  PLoS One  2010  5(11):e13932  PubMed ID: 21085684
16518  Li F, Awale S, Tezuka Y, Kadota S.  Cytotoxicity of constituents from Mexican propolis against a panel of six different cancer cell lines  Nat Prod Commun  2010  5(10):1601-6.  PubMed ID: 21121257
8436  Li F, Awale S, Tezuka Y, Kadota S.  Cytotoxic constituents of propolis from Myanmar and their structure-activity relationship.  Biol. Pharm. Bull.  2009  32:2075-8  PubMed ID: 19952433
8509  Awale S, Miyamoto T, Linn TZ, Li F, Win NN, Tezuka Y, Esumi H, Kadota S.  Cytotoxic constituents of Soymida febrifuga from Myanmar.  J. Nat. Prod.  2009  72:1631-6  PubMed ID: 19689125
8605  Asano S, Hamao K, Hosoya H.  Direct evidence for roles of phosphorylated regulatory light chain of myosin II in furrow ingression during cytokinesis in HeLa cells.  Genes Cells  2009  14:555-68  PubMed ID: 19371382
8606  Hamao K, Morita M, Hosoya H.  New function of the proline rich domain in dynamin-2 to negatively regulate its interaction with microtubules in mammalian cells.  Exp. Cell Res.  2009  315:1336-45  PubMed ID: 19331814
8644  Yamamoto N, Takemori Y, Sakurai M, Sugiyama K, Sakurai H.  Differential recognition of heat shock elements by members of the heat shock transcription factor family.  FEBS J.  2009  276:1962-74  PubMed ID: 19250318
8677  Koichi Baba, Hitoshi Kasai, Akito Masuhara, Hidetoshi Oikawa, and Hachiro Nakanishi  Organic Solvent-Free Fluorescence Confocal Imaging of Living Cells Using Pure Nanocrystal Forms of Fluorescent Dyes  Jpn J Appl Phys.  2009  48:117002-1-117002-4 
6301  Kariya Y, Honma M, Aoki S, Chiba A, Suzuki H.  Vps33a mediates RANKL storage in secretory lysosomes in osteoblastic cells.  J Bone Miner Res  2009  24(10):1741-52  PubMed ID: 19419298
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309
10911  Kayoko Kawai, Akiko Saito, Tatsuhiko Sudo, Hiroyuki Osada  A p38 Mitogen-Activated Protein Kinase Inhibitor Screening Method Using Growth Recovery of Escherichia Coli as an Index  Anal Biochem  2009  388(1):128-33  PubMed ID: 19248755
16556  Nakase I, Hirose H, Tanaka G, Tadokoro A, Kobayashi S, Takeuchi T, Futaki S.  Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis  Mol Ther  2009  17(11):1868-76  PubMed ID: 19707187
8759  Watanabe S, Wakasugi K.  Zebrafish neuroglobin is a cell-membrane-penetrating globin.  Biochemistry  2008  47:5266-70  PubMed ID: 18416560
3576  Ikeda M, Kanouchi H, Minatogawa Y.  Characterization of peroxisomal targeting signals on alanine: glyoxylate aminotransferase.  Biol Pharm Bull  2008  31(1):131-4  PubMed ID: 18175955
9068  Yasuhiro Yamasaki, Daisuke Katsuo, Seiichiro Nakayasu, Cristina Salati, JingJing Duan, Yanan Zou, Yukihiko Matsuyama, Kenichi Yamaguchi, Tatsuya Oda  Purification and Characterization of a Novel High Molecular Weight Exotoxin Produced by Red Tide Phytoplankton, Alexandrium Tamarense  J Biochem Mol Toxicol  2008  22 (6), 405-15  PubMed ID: 19111002
12794  Takahashi T, Okuno M, Okamoto T, Kishi T.  NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells  Biofactors  2008  32(1-4):59-70  PubMed ID: 19096101
16645  Li F, Awale S, Tezuka Y, Kadota S.  Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship  Bioorg Med Chem  2008  16(10):5434-40  PubMed ID: 18440233
16656  Shimizu N, Yoshikawa N, Wada T, Handa H, Sano M, Fukuda K, Suematsu M, Sawai T, Morimoto C, Tanaka H.  Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes by hexamethylene bisacetamide-inducible protein 1  Mol Endocrinol  2008  22(12):2609-23  PubMed ID: 18801933
8791  Wakasugi K.  Human tryptophanyl-tRNA synthetase binds with heme to enhance its aminoacylation activity.  Biochemistry  2007  46:11291-8  PubMed ID: 17877375
8808  Nakayama T, Nomura N, Matsumura M.  The effect of copper concentration on the virulence of pathogenic Vibrio harveyi.  J. Appl. Microbiol.  2007  102:1300-6  PubMed ID: 17448165
3577  Ikeda M, Inoue S, Muramatsu M, Minatogawa Y.  Characterization and identification of a steroid receptor-binding protein, SRB-RGS.  Biol Pharm Bull  2007  30(6):1056-64  PubMed ID: 17541154
7380  Yamamoto T, Kambe F, Cao X, Lu X, Ishiguro N, Seo H.  Parathyroid hormone activates phosphoinositide 3-kinase-Akt-Bad cascade in osteoblast-like cells.  Bone  2007  40(2):354-9  PubMed ID: 17046344
9059  Y-C Jung, E Mizuki, T Akao, J-C Côté  Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells  J Appl Microbiol  2007  103 (1), 65-79  PubMed ID: 17584453
9060  Paola Neri, Saori Itoh Nagano, Shin-ichiro Yokoyama, Hirofumi Dohi, Kazukiyo Kobayashi, Tsuyoshi Miura, Toshiyuki Inazu, Tsuyoshi Sugiyama, Yoshihiro Nishida, Hiroshi Mori  Neutralizing Activity of Polyvalent Gb3, Gb2 and Galacto-Trehalose Models Against Shiga Toxins  Microbiol Immunol  2007  51 (6), 581-92  PubMed ID: 17579269
16605  Hama S, Akita H, Iida S, Mizuguchi H, Harashima H.  Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex  Nucleic Acids Res  2007  1533-43  PubMed ID: 17287293
3389  Akita, Hidetaka, Tanimoto, Mitsuhide, Masuda, Tomoya, Kogure, Kentaro, Hama, Susumu, Ninomiya, Keiko, Futaki, Shiroh, Harashima, Hideyoshi  Evaluation of the nuclear delivery and intra-nuclear transcription of plasmid DNA condensed with micro (mu) and NLS-micro by cytoplasmic and nuclear microinjection: a comparative study with poly-L-lysine.  J Gene Med  2006  8:198-206  PubMed ID: 16285003
8810  Sasaki Y, Matsui K, Aoyama Y, Kikuchi J.  Cerasome as an infusible and cell-friendly gene carrier: synthesis of cerasome-forming lipids and transfection using cerasome.  Nat Protoc  2006  1:1227-34  PubMed ID: 17406406
8856  Miyauchi K, Yamamoto Y, Kosaka T, Hosoya H.  Myosin II activity is not essential for recruitment of myosin II to the furrow in dividing HeLa cells.  Biochem. Biophys. Res. Commun.  2006  350:543-8  PubMed ID: 17022938
8860  Horiuchi S, Aoyama Y.  Systematic lactose-functionalization of amphiphilic octaamine macrocycle as a gene carrier. Optimization of the charge, size, toxicity, and receptor factors for hepatocyte targeting.  J Control Release  2006  116:107-14  PubMed ID: 16905218
8864  Nakayama T, Nomura N, Matsumura M.  Study on the relationship of protease production and luminescence in Vibrio harveyi.  J. Appl. Microbiol.  2006  101:200-5  PubMed ID: 16834607
8880  Nakayama T, Ito E, Nomura N, Nomura N, Matsumura M.  Comparison of Vibrio harveyi strains isolated from shrimp farms and from culture collection in terms of toxicity and antibiotic resistance.  FEMS Microbiol. Lett.  2006  258:194-9  PubMed ID: 16640572
8903  Matsui K, Horiuchi S, Sando S, Sera T, Aoyama Y.  RNAi silencing of exogenous and endogenous reporter genes using a macrocyclic octaamine as a "compact" siRNA carrier. Studies on the nonsilenced residual activity.  Bioconjug. Chem.  2006  17:132-8  PubMed ID: 16417261
6447  Yasutake K, Binh ND, Kagoshima K, Uemori A, Ohgushi A, Maeda M, Mizuki E, Yu YM, Ohba M.  Occurrence of parasporin-producing Bacillus thuringiensis in Vietnam.  Can J Microbiol  2006  52(4):365-72  PubMed ID: 16699587
3335  Yoshino K, Iimura E, Saijo K, Iwase S, Fukami K, Ohno T, Obata Y, Nakamura Y.  Essential role for gene profiling analysis in the authentication of human cell lines.  Hum Cell  2006  19(1):43-8  PubMed ID: 16643607
12298  Reiko Hayashi, Yuya Goto, Ryuji Ikeda, Kazunari K Yokoyama, Kenichi Yoshida  CDCA4 is an E2F transcription factor family-induced nuclear factor that regulates E2F-dependent transcriptional activation and cell proliferation  J Biol Chem  2006  281(47):35633-48  PubMed ID: 16984923
15552  Maeshima K, Yahata K, Sasaki Y, Nakatomi R, Tachibana T, Hashikawa T, Imamoto F, Imamoto N.  Cell-cycle-dependent dynamics of nuclear pores: pore-free islands and lamins  J Cell Sci   2006  119(Pt 21):4442-51  PubMed ID: 17074834
3413  Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio  Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.  J Biochem  2005  138:663-72  PubMed ID: 16428294
2892  Katayama H, Yokota H, Akao T, Nakamura O, Ohba M, Mekada E, Mizuki E  Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis  J Biochem (Tokyo)  2005  137:17-25  PubMed ID: 15713879
2955  Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H  The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor.  Mol Endocrinol  2005  19:1110-24  PubMed ID: 15677712
2844  Mise-Omata S, Obata Y, Iwase S, Mise N, Doi TS.  Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells.  Biochem Biophys Res Commun  2005  328(4):1034-42  PubMed ID: 15707982
2861  Tsuji AB, Sudo H, Sugyo A, Otsuki M, Miyagishi M, Taira K, Imai T, Harada YN.  A fast, simple method for screening radiation susceptibility genes by RNA interference.  Biochem Biophys Res Commun  2005  333(4):1370-7  PubMed ID: 15979584
2881  Fukushima-Nakase Y, Naoe Y, Taniuchi I, Hosoi H, Sugimoto T, Okuda T.  Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.  Blood  2005  105(11):4298-307  PubMed ID: 15713794
2957  Isogawa Y, Kon T, Inoue T, Ohkura R, Yamakawa H, Ohara O, Sutoh K.  The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site.  Biochemistry  2005  44(16):6190-6  PubMed ID: 15835906
3001  Shimoi W, Ezawa I, Nakamoto K, Uesaki S, Gabreski G, Aridor M, Yamamoto A, Nagahama M, Tagaya M, Tani K.  p125 is localized in endoplasmic reticulum exit sites and involved in their organization.  J Biol Chem  2005  280(11):10141-8  PubMed ID: 15623529
9047  Takuji Nakashima, Tadashi Tamura, Maki Kurachi, Kenichi Yamaguchi, Tatsuya Oda  Apoptosis-mediated Cytotoxicity of Prodigiosin-Like Red Pigment Produced by gamma-Proteobacterium and Its Multiple Bioactivities  Biol Pharm Bull  2005  28 (12), 2289-95  PubMed ID: 16327167
9048  Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye  Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines  J Agric Food Chem  2005  53 (16), 6313-8  PubMed ID: 16076112
15551  Hirohisa Matsushita, Hiroaki Kuwabara, Satoko Ishikawa, Masataka Mochizuki  Apoptosis Induced in Human Cell Lines by a Butanol Extract from Chlorophytum comosum Roots  Journal of Health Science  2005  51:341-345 
2894  Ito, Akio, Sasaguri, Yasuyuki, Kitada, Sakae, Kusaka, Yoshitomo, Kuwano, Kyoko, Masutomi, Kenjiro, Mizuki, Eiichi, Akao, Tetsuyuki, Ohba, Michio  A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.  J Biol Chem  2004  279:21282-6  PubMed ID: 15026424
2702  Futaki S, Niwa M, Nakase I, Tadokoro A, Zhang Y, Nagaoka M, Wakako N, Sugiura Y.  Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins.  Bioconjug Chem  2004  15(3):475-81  PubMed ID: 15149174
2887  Gu W, Ogose A, Kawashima H, Ito M, Ito T, Matsuba A, Kitahara H, Hotta T, Tokunaga K, Hatano H, Morita T, Urakawa S, Yoshizawa T, Kawashima H, Kuwano R, Endo N.  High-level expression of the coxsackievirus and adenovirus receptor messenger RNA in osteosarcoma, Ewing's sarcoma, and benign neurogenic tumors among musculoskeletal tumors.  Clin Cancer Res  2004  10(11):3831-8  PubMed ID: 15173092
2992  Kazuhiko OCHIAI, Masami MORIMATSU2, Yasunaga YOSHIKAWA, Bunei SYUTO and Kazuyoshi HASHIZUM  Brca2 C-terminus interacts with Rad51 and contributes to nuclear focus for-mation in double-strand break repair of DNA  Biomedical Research  2004  25:269-275 
3002  Nagahama M, Hara Y, Seki A, Yamazoe T, Kawate Y, Shinohara T, Hatsuzawa K, Tani K, Tagaya M.  NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence.  Mol Biol Cell  2004  15(12):5712-23  PubMed ID: 15469983
3004  Hirose H, Arasaki K, Dohmae N, Takio K, Hatsuzawa K, Nagahama M, Tani K, Yamamoto A, Tohyama M, Tagaya M.  Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.  EMBO J  2004  23(6):1267-78  PubMed ID: 15029241
3179  Kajimoto T, Shirai Y, Sakai N, Yamamoto T, Matsuzaki H, Kikkawa U, Saito N.  Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex.  J Biol Chem  2004  279(13):12668-76  PubMed ID: 14715667
3181  Suico MA1, Yoshida H, Seki Y, Uchikawa T, Lu Z, Shuto T, Matsuzaki K, Nakao M, Li JD, Kai H.  Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein.  J Biol Chem  2004  279(18):19091-8  PubMed ID: 14976184
3196  Hattori M, Suzuki AZ, Higo T, Miyauchi H, Michikawa T, Nakamura T, Inoue T, Mikoshiba K.  Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.  J Biol Chem  2004  279(12):11967-75  PubMed ID: 14707143
16654  Hara T, Ishii T, Fujishiro M, Masuda M, Ito T, Nakajima J, Inoue T, Matsuse T.  Glutathione S-transferase P1 has protective effects on cell viability against camptothecin  Cancer Lett  2004  203(2):199-207.  PubMed ID: 14732228
2701  Tamura M, Natori K, Kobayashi M, Miyamura T, Takeda N  Inhibition of attachment of virions of Norwalk virus to mammalian cells by soluble histone molecules.  Arch Virol  2003  148:1659-70  PubMed ID: 14505080
3005  Kawase K, Shibata M, Kawashima H, Hatsuzawa K, Nagahama M, Tagaya M, Tani K.  Gaf-1b is an alternative splice variant of Gaf-1/Rip11.  Biochem Biophys Res Commun  2003  303(4):1042-6  PubMed ID: 12684040
3006  Nagahama M, Suzuki M, Hamada Y, Hatsuzawa K, Tani K, Yamamoto A, Tagaya M.  SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation.  Mol Biol Cell  2003  14(1):262-73  PubMed ID: 12529442
6275  Nakai T, Kanamori T, Sando S, Aoyama Y.  Remarkably size-regulated cell invasion by artificial viruses. Saccharide-dependent self-aggregation of glycoviruses and its consequences in glycoviral gene delivery.  J Am Chem Soc  2003  125(28):8465-75  PubMed ID: 12848552
6401  Tsuchiya Y, Nakajima M, Itoh S, Iwanari M, Yokoi T.  Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines.  Toxicol Sci  2003  72(2):253-9  PubMed ID: 12655030
9038  Masahiro Nagahama, Shinya Hayashi, Shinsuke Morimitsu, Jun Sakurai  Biological Activities and Pore Formation of Clostridium Perfringens Beta Toxin in HL 60 Cells  J Biol Chem  2003  278 (38), 36934-41  PubMed ID: 12851396
4462  Ogata M, Inanami O, Nakajima M, Nakajima T, Hiraoka W, Kuwabara M.  Ca(2+)-dependent and caspase-3-independent apoptosis caused by damage in Golgi apparatus due to 2,4,5,7-tetrabromorhodamine 123 bromide-induced photodynamic effects  Photochem Photobiol  2003  78(3):241-7.  PubMed ID: 14556310
2648  Ugai H, Watanabe S, Suzuki E, Tsutsui-Nakata H, Yokoyama KK, Murata T.  Stability of a recombinant adenoviral vector: optimization of conditions for storage, transport and delivery.  Jpn J Cancer Res  2002  93(5):598-603  PubMed ID: 12036457
2667  Suzuki T, Futaki S, Niwa M, Tanaka S, Ueda K, Sugiura Y.  Possible existence of common internalization mechanisms among arginine-rich peptides.  J Biol Chem  2002  277(4):2437-43  PubMed ID: 11711547
13696  Takashi KANAZAWA, Masahiko WATANABE, Fumihiko KANZAWA, Yuko MATSUSHIMA-HIBIYA, Kotaro KOYAMA, Noriaki TANAKA, Takashi SUGIMURA, Keiji WAKABAYASHI  Pierisin-1 from cabbage butterfly suppresses HeLa tumor growth in nude mice  Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences  2002  8:305-308 
15594  Ueda K, Murata-Hori M, Tatsuka M, Hosoya H.  Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells  Oncogene  2002  21(38):5852-60  PubMed ID: 12185584
15618  MASAKI YODA, KEISUKE G TAKAHASHI, KATSUYOSHI MORI  Telomerase activity detected in eyed embryos of rainbow trout Oncorhynchus mykiss  Fisheries Science  2002  68:132-137 
15619  MASAKI YODA, KEISUKE G. TAKAHASHI, KATSUYOSHI MORI  Telomerase expression in normal cells from the kidney of masu salmon, Oncorhynchus masou  Fisheries science  2002  68:1299-1300 
16609  Nagaoka T, Banskota AH, Tezuka Y, Saiki I, Kadota S.  Selective antiproliferative activity of caffeic acid phenethyl ester analogues on highly liver-metastatic murine colon 26-L5 carcinoma cell line  Bioorg Med Chem  2002  10(10):3351-9  PubMed ID: 12150882
5965  Suzuki J, Ohnsihi H, Shibata H, Wada A, Hirayama T, Iiri T, Ueda N, Kanamaru C, Tsuchida T, Mashima H, Yasuda H, Fujita T.  Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA.  J Clin Invest  2001  107(3):363-70  PubMed ID: 11160160
2531  Masters JR, Thomson JA, Daly-Burns B, Reid YA, Dirks WG, Packer P, Toji LH, Ohno T, Tanabe H, Arlett CF, Kelland LR, Harrison M, Virmani A, Ward TH, Ayres KL, Debenham PG.  Short tandem repeat profiling provides an international reference standard for human cell lines.  Proc Natl Acad Sci U S A.  2001  98(14):8012-7  PubMed ID: 11416159
9028  M Ogasawara, T Suzutani, I Yoshida, M Azuma  Role of the UL25 Gene Product in Packaging DNA Into the Herpes Simplex Virus Capsid: Location of UL25 Product in the Capsid and Demonstration That It Binds DNA  J Virol  2001  75 (3), 1427-36  PubMed ID: 11152516
13875  Satoh JI, Kuroda Y.  Alpha-synuclein expression is up-regulated in NTera2 cells during neuronal differentiation but unaffected by exposure to cytokines and neurotrophic factors  Parkinsonism Relat Disord  2001  8(1):7-17  PubMed ID: 11472875
15595  Murata-Hori M, Fukuta Y, Ueda K, Iwasaki T, Hosoya H.  HeLa ZIP kinase induces diphosphorylation of myosin II regulatory light chain and reorganization of actin filaments in nonmuscle cells  Oncogene  2001  20(57):8175-8  PubMed ID: 11781833
15620  Cantarelli VV, Takahashi A, Yanagihara I, Akeda Y, Imura K, Kodama T, Kono G, Sato Y, Honda T.  Talin, a host cell protein, interacts directly with the translocated intimin receptor, Tir, of enteropathogenic Escherichia coli, and is essential for pedestal formation  Cell Microbiol  2001  3:745-51  PubMed ID: 11696034
15624  Ishida R, Takashima R, Koujin T, Shibata M, Nozaki N, Seto M, Mori H, Haraguchi T, Hiraoka Y.  Mitotic specific phosphorylation of serine-1212 in human DNA topoisomerase IIalpha  Cell Struct Funct  2001  26(4):215-26  PubMed ID: 11699638
16517  Fukusaki E, Oishi T, Tanaka H, Kajiyama S, Kobayashi A.  Identification of genes induced by taxol application using a combination of differential display RT-PCR and DNA microarray analysis  Z Naturforsch C J Biosci  2001  56(9-10):814-9  PubMed ID: 11724388
3011  Hatsuzawa K, Hirose H, Tani K, Yamamoto A, Scheller RH, Tagaya M.  Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking.  J Biol Chem  2000  275(18):13713-20  PubMed ID: 10788491
3978  Tanioka T, Nakatani Y, Semmyo N, Murakami M, Kudo I.  Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis.  J Biol Chem  2000  275(42):32775-82  PubMed ID: 10922363
5968  Satoh J, Kuroda Y.  Beta-catenin expression in human neural cell lines following exposure to cytokines and growth factors.  Neuropathology  2000  20(2):113-23  PubMed ID: 10935448
3524  Nie Z, Ning W, Amagai M, Hashimoto T.  C-Terminus of desmoyokin/AHNAK protein is responsible for its translocation between the nucleus and cytoplasm.  J Invest Dermatol  2000  114(5):1044-9  PubMed ID: 10771490
9024  Vlademir Cantarelli; Kenichi Nagayama; Akira Takahashi; Takeshi Honda; Paulo F. Cauduro; Cícero A.G. Dias; Adelina Mezzari; Teresa Brodt  Isolation of Shiga toxin-producing Escherichia coli (STEC) serotype 091: H21 from a child with diarrhea in Porto Alegre city, RS, Brazil  Brazilian Journal of Microbiology  2000  31:266-270 
1507  Hino M, Kurogi K, Okubo MA, Murata-Hori M, Hosoya H.  Small heat shock protein 27 (HSP27) associates with tubulin/microtubules in HeLa cells  Biochem Biophys Res Commun  2000  271(1):164-9  PubMed ID: 10777697
1897  Lee DW, Akao T, Yamashita S, Katayama H, Maeda M, Saitoh H, Mizuki E, Ohba M.  Noninsecticidal parasporal proteins of a Bacillus thuringiensis serovar shandongiensis isolate exhibit a preferential cytotoxicity against human leukemic T cells  Biochem Biophys Res Commun  2000  272(1):218-23  PubMed ID: 10872830
11971  Watabe M, Kakeya H, Onose R, Osada H.  Activation of MST/Krs and c-Jun N-terminal kinases by different signaling pathways during cytotrienin A-induced apoptosis  J Biol Chem  2000  275(12):8766-71  PubMed ID: 10722720
2382  Niidome T, Takaji K, Urakawa M, Ohmori N, Wada A, Hirayama T, Aoyagi H  Chain length of cationic alpha-helical peptide sufficient for gene delivery into cells.  Bioconjug Chem  1999  10:773-80  PubMed ID: 10502342
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6163  Makino Y, Yoshikawa N, Okamoto K, Hirota K, Yodoi J, Makino I, Tanaka H.  Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function.  J Biol Chem  1999  274(5):3182-8  PubMed ID: 9915858
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