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細胞番号 : 細胞名
RCB0001 : Vero  update : 2023/12/25
細胞特性(Comment:英)CITES. A cell line derived from kidney of African green monkey. Susceptible to many kinds of virus. Useful for development of vaccine. Used as an indicator cell line for mycoplasma testing. Require import and export permits according to the Convention on International Trade in Endangered Species (CITES). Origin animal species details
使用条件(英)There is no restriction regarding use for basic researches. In relation to the use by for-profit entities and/or the use for profit (commercial use, patent filing, etc.), a prior written permission of the DEPOSITOR is necessary.
260-8670 千葉県 千葉市中央区亥鼻1-8-1
未来医療教育研究 機構 先生
Fax. 043-226-2832

提供申込書類(英) Order Form(C-0005.pdf)   Approval Form(C-0006.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   承諾書C-0002.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Simizu, Bunsiti
樹立者 Yasumura, Y. & Kawakita, Y.
寄託日 1988
動物種 _monkey < Mammals
動物系統名 African green Origin animal species details
属名 Cercopithecus
種名 aethiops
採取組織 kidney
転移 No
細胞分類 other
初代培養日 1962
入手歴 at passage 110 from Prof. B. S850821
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0059
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 MEM + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
ウィルス(HIV) (-)
アイソザイム検査 LD, NP, AST
染色体検査 54-61(50) : 54(1),56(1),58(6),59(38),60(2),61(2)
文献情報 Reference(英) 6件
Reference(日) 3件
利用者成果(英) 82件
利用者成果(日) 0件

4  Shimizu E, Shirasawa H, Kodama K, Sato T, Simizu B.  Expression, regulation and polymorphism of the mxi1 genes  Gene  1996  176(1-2):45-8  PubMed ID: 8918230   DOI: 10.1016/0378-1119(96)00206-5
966  Simizu, B. and Terasima, T. (eds)  Vero Cells - Origin, Properties and Biomedical Applications  Vero Cells - Origin, Properties and Biomedical Applications.  1988  1-234   
361  Rhim, J S, Schell K, Creasy B, Case W  Biological characteristics and viral susceptibility of an African green monkey kidney cell line (Vero).  Proc Soc Exp Biol Med  1969  132:670-8  PubMed ID: 4982209   DOI: 10.3181/00379727-132-34285
3  Rhim JS, Simizu B, Wiebenga NH.  Multiplication of Machupo virus, the etiological agent of Bolivian hemorrhagic fever, in cell cultures  Proc Soc Exp Biol Med  1969  130(2):382-7  PubMed ID: 5765269   DOI: 10.3181/00379727-130-33560
1  Simizu B, Rhim JS, Wiebenga NH.  Characterization of the Tacaribe group of arboviruses. I. Propagation and plaque assay of Tacaribe virus in a line of African green monkey kidney cells (Vero)  Proc Soc Exp Biol Med  1967  125(1):119-23  PubMed ID: 6027511   DOI: 10.3181/00379727-125-32029
2  Rhim JS, Simizu B, Wiebenga NH.  Growth of Junin virus, the etiological agent of Argentinian hemorrhagic fever, in cell cultures  Arch Gesamte Virusforsch  1967  21(2):243-5  PubMed ID: 5591575   DOI: 10.1007/BF01241448

1710  安村美博  アフリカミドリザル : Vero  生体の科学  1992  43:402-403   
359  Ito, H. et al  アフリカミドリザル腎細胞由来ー株細胞 Vero  組織培養  1981  7:43294   
360  Yasumura, Y. et al  組織培養によるSV40の研究 --- ガラス器内における癌研究の予備段階 ---  日本臨床  1963  21:175-179   

17565  Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y.  Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists  iScience  2023  26(1):105742  PubMed ID: 36507221   DOI: 10.1016/j.isci.2022.105742
21334  Tashiro K, Segawa T, Futami T, Suzuki M, Itou T.  Establishment and characterization of a novel kidney cell line derived from the common bottlenose dolphin.  In Vitro Cell Dev Biol Anim  2023    PubMed ID: 37524977   DOI: 10.1007/s11626-023-00786-y
17638  Jimbo E, Kobayashi T, Takeshita A, Mine K, Nagafuchi S, Fukui T, Yagihashi S.  Immunohistochemical detection of enteroviruses in pancreatic tissues of patients with type 1 diabetes using a polyclonal antibody against 2A protease of Coxsackievirus  J Diabetes Investig  2022  13(3):435-442  PubMed ID: 34669264   DOI: 10.1111/jdi.13700
20618  Shimizu T, Matsuo-Takasaki M, Luijkx D, Takami M, Arai Y, Noguchi M, Nakamura Y, Hayata T, Saito MK, Hayashi Y.  Generation of human induced pluripotent stem cell lines derived from four DiGeorge syndrome patients with 22q11.2 deletion.  Stem Cell Res  2022  61:102744  PubMed ID: 35292424   DOI: 10.1016/j.scr.2022.102744
20923  Isobe A, Arai Y, Kuroda D, Okumura N, Ono T, Ushiba S, Nakakita SI, Daidoji T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.  ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner.  Commun Biol  2022  5(1):1188  PubMed ID: 36335195   DOI: 10.1038/s42003-022-04170-6
18099  Kato T, Nakamori M, Matsumura S, Nakamura M, Ojima T, Fukuhara H, Ino Y, Todo T, Yamaue H.  Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer  Oncol Lett  2021  21(6):490  PubMed ID: 33968206   DOI: 10.3892/ol.2021.12751
14066  Yada Y, Kondo T, Suga M, Tsukita K, Enami T, Shibukawa R, Sagara Y, Okanishi Y, Imamura K, Kihara T, Inoue H.  Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification  Stem Cell Res  2021  53:102274  PubMed ID: 33714066   DOI: 10.1016/j.scr.2021.102274
20174  Tsukamoto S, Nakade K, Wakabayashi T, Nakashima K, Takami M, Hemmi Y, Kuramochi Y, Shimizu T, Arai Y, Matsuo-Takasaki M, Noguchi M, Nakamura Y, Miwa Y, Hayashi Y.  Generation of two ISL1-tdTomato reporter human induced pluripotent stem cell lines using CRISPR-Cas9 genome editing.  Stem Cell Res  2021  53:102363  PubMed ID: 34087992   DOI: 10.1016/j.scr.2021.102363
20398  Ohtsuka J, Imai M, Fukumura M, Maeda M, Eguchi A, Ono R, Maemura T, Ito M, Yamayoshi S, Kataoka Y, Kawaoka Y, Nosaka T.  Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2.  iScience  2021  103379  PubMed ID: 34805782   DOI: 10.1016/j.isci.2021.103379
16130  Yajima S, Sugawara K, Iwai M, Tanaka M, Seto Y, Todo T.  Efficacy and safety of a third-generation oncolytic herpes virus G47Δ in models of human esophageal carcinoma  Mol Ther Oncolytics  2021  ;23:402-411  PubMed ID: 34853811   DOI: 10.1016/j.omto.2021.10.012
16433  Fukuchi K, Koshikawa T, Asai D, Inomata M, Sakagami H, Takemura H, Kanamoto T, Aimi H, Kikkawa Y.  Lignosulfonate Rapidly Inactivates Human Immunodeficiency and Herpes Simplex Viruses  Medicines (Basel)   2021  8(10):56  PubMed ID: 34677485   DOI: 10.3390/medicines8100056
16829  Yada Y, Suga M, Shibukawa R, Sagara Y, Okanishi Y, Enami T, Tsukita K, Kondo T, Imamura K, Sugihara G, Murai T, Inoue H.  Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins  Stem Cell Res  2021  55:102504  PubMed ID: 34419750   DOI: 10.1016/j.scr.2021.102504
16879  Kuramochi Y, Awaya T, Matsuo-Takasaki M, Takami M, An Y, Li J, Hemmi Y, Wakabayashi T, Arai Y, Inoue J, Noguchi M, Nakamura Y, Asaka I, Akimoto K, Saito MK, Hayashi Y.  Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations  Stem Cell Res  2021  53:102337  PubMed ID: 33901816   DOI: 10.1016/j.scr.2021.102337
9897  Yutaka Arai, Miho Takami, Yuri An, Mami Matsuo-Takasaki, Yasuko Hemmi, Tamami Wakabayashi, Jun Inoue, Michiya Noguchi, Yukio Nakamura, Keisuke Sugimoto, Tsukasa Takemura, Keisuke Okita, Kenji Osafune, Minoru Takasato, Tadayoshi Hayata, Yohei Hayashi  Generation of Two Human Induced Pluripotent Stem Cell Lines Derived From Two Juvenile Nephronophthisis Patients With NPHP1 Deletion  Stem Cell Res  2020  45:101815  PubMed ID: 32361464   DOI: 10.1016/j.scr.2020.101815
12341  Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H.  Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration  Stem Cell Res  2020  45:101787  PubMed ID: 32416577   DOI: 10.1016/j.scr.2020.101787
12344  Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H.  Generation of a human induced pluripotent stem cell line, BRCi005-A, derived from a Best disease patient with BEST1 mutations  Stem Cell Res  2020  45:101782  PubMed ID: 32416576   DOI: 10.1016/j.scr.2020.101782
12345  Katagami Y, Kondo T, Suga M, Yada Y, Imamura K, Shibukawa R, Sagara Y, Okanishi Y, Tsukita K, Hirayama K, Era T, Inoue H.  Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a  Stem Cell Res  2020  49:102095  PubMed ID: 33291009   DOI: 10.1016/j.scr.2020.102095
13613  Saito H, Murata Y, Nonaka M, Kato K.  Screening of a library of traditional Chinese medicines to identify compounds and extracts which inhibit Toxoplasma gondii growth  J Vet Med Sci  2020  82(2):184-187.  PubMed ID: 31904004   DOI: 10.1292/jvms.19-0241
13628  Han Y, Adeyemi OS, Kabir MHB, Kato K.  Screening of compound libraries for inhibitors of Toxoplasma growth and invasion  Parasitol Res  2020  119(5):1675-1681  PubMed ID: 32236711   DOI: 10.1007/s00436-020-06673-9
14846  Esaki S, Goshima F, Ozaki H, Takano G, Hatano Y, Kawakita D, Ijichi K, Watanabe T, Sato Y, Murata T, Iwata H, Shibamoto Y, Murakami S, Nishiyama Y, Kimura H.  Oncolytic activity of HF10 in head and neck squamous cell carcinomas  Cancer Gene Ther   2020  27(7-8):585-59  PubMed ID: 31477804   DOI: 10.1038/s41417-019-0129-3
16897  Takano G, Esaki S, Goshima F, Enomoto A, Hatano Y, Ozaki H, Watanabe T, Sato Y, Kawakita D, Murakami S, Murata T, Nishiyama Y, Iwasaki S, Kimura H.  Oncolytic activity of naturally attenuated herpes-simplex virus HF10 against an immunocompetent model of oral carcinoma  Mol Ther Oncolytics  2020  20:220-227  PubMed ID: 33665360   DOI: 10.1016/j.omto.2020.12.007
11776  Vinh PT, Shinohara Y, Yamada A, Duc HM, Nakayama M, Ozawa T, Sato J, Masuda Y, Honjoh KI, Miyamoto T.  Baicalein Inhibits Stx1 and 2 of EHE: Effects of Baicalein on the Cytotoxicity, Production, and Secretion of Shiga Toxins of Enterohaemorrhagic Escherichia coli.  Toxins (Basel)  2019    PubMed ID: 31470657   DOI: 10.3390/toxins11090505
9129  Hideyuki Matsushima, Masaki Kaibori, Masahiko Hatta, Morihiko Ishizaki, Richi Nakatake, Tadayoshi Okumura, Kengo Yoshii, Tomoki Todo  Efficacy of a Third-Generation Oncolytic Herpes Simplex Virus in Neuroendocrine Tumor Xenograft Models  Oncotarget  2019  10 (67), 7132-7141  PubMed ID: 31903171   DOI: 10.18632/oncotarget.27391
13006  Suga M, Kondo T, Imamura K, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Enami T, Furujo M, Saijo K, Nakamura Y, Osawa M, Saito MK, Yamanaka S, Inoue H.  Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I.  Stem Cell Res  2019    PubMed ID: 30849633   DOI: 10.1016/j.scr.2019.101406
11494  Shima T, Morikawa M, Kaneshiro J, Kambara T, Kamimura S, Yagi T, Iwamoto H, Uemura S, Shigematsu H, Shirouzu M, Ichimura T, Watanabe TM, Nitta R, Okada Y, Hirokawa N.  Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport.  J. Cell Biol.  2018  217(12):4164-4183  PubMed ID: 30297389   DOI: 10.1083/jcb.201711178
4370  Nakatake R, Kaibori M, Nakamura Y, Tanaka Y, Matushima H, Okumura T, Murakami T, Ino Y, Todo T, Kon M.  Third-generation oncolytic herpes simplex virus inhibits the growth of liver tumors in mice.  Cancer Sci.  2018  109(3):600-610  PubMed ID: 29288515   DOI: 10.1111/cas.13492
4465  Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Kajikawa J, Hiramatsu H, Sriwilaijaroen N, Ono T, Takagi T, Takahashi K, Shioda T, Matsumoto K, Suzuki Y, Nakaya T.  Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells.  J. Virol.  2018  92(11)  PubMed ID: 29563293   DOI: 10.1128/JVI.02004-17
10268  Sato Y, Koshizuka T, Ishibashi K, Hashimoto K, Ishioka K, Ikuta K, Yokota SI, Fujii N, Suzutani T.  Involvement of herpes simplex virus type 1 UL13 protein kinase in induction of SOCS genes, the negative regulators of cytokine signaling.  Microbiol. Immunol.  2017  61:159-167  PubMed ID: 28419615   DOI: 10.1111/1348-0421.12483
10350  Murata Y, Sugi T, Weiss LM, Kato K.  Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites.  PLoS ONE  2017  12:e0178203  PubMed ID: 28609444   DOI: 10.1371/journal.pone.0178203
9121  Rui Tanaka, Fumi Goshima, Shinichi Esaki, Yoshitaka Sato, Takayuki Murata, Yukihiro Nishiyama, Daisuke Watanabe, Hiroshi Kimura  The Efficacy of Combination Therapy With Oncolytic Herpes Simplex Virus HF10 and Dacarbazine in a Mouse Melanoma Model  Am J Cancer Res  2017  7 (8), 1693-1703  PubMed ID: 28861325  
9872  Liu W, Al-Oweini R, Meadows K, Bassil BS, Lin Z, Christian JH, Dalal NS, Bossoh AM, Mbomekallé IM, de Oliveira P, Iqbal J, Kortz U.  CrIII-Substituted Heteropoly-16-Tungstates [CrIII2(B-β-XIVW8O31)2]14- (X = Si, Ge): Magnetic, Biological, and Electrochemical Studies.  Inorg Chem  2016  55:10936-10946  PubMed ID: 27768287   DOI: 10.1021/acs.inorgchem.6b01458
9117  Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masaya Takehara, Masahiro Nagahama  Clostridium Perfringens Delta-Toxin Induces Rapid Cell Necrosis  PLoS One  2016  11 (1), e0147957  PubMed ID: 26807591   DOI: 10.1371/journal.pone.0147957
9115  Muhammad Ali Hashmi, Hamid Saeed Shah, Afsar Khan, Umar Farooq, Jamshed Iqbal, Viqar Uddin Ahmad and Shagufta Perveen  Anticancer and Alkaline Phosphatase Inhibitory Effects of Compounds Isolated from the Leaves of Olea ferruginea Royle  Rec Nat Prod  2015  9: 164-168   
9104  Fumi Goshima, Shinichi Esaki, Chenhong Luo, Maki Kamakura, Hiroshi Kimura, Yukihiro Nishiyama  Oncolytic Viral Therapy With a Combination of HF10, a Herpes Simplex Virus Type 1 Variant and Granulocyte-Macrophage Colony-Stimulating Factor for Murine Ovarian Cancer  Int J Cancer  2014  134 (12), 2865-77  PubMed ID: 24265099   DOI: 10.1002/ijc.28631
9105  Takahisa Miyamoto, Seiyo Toyofuku, Narumi Tachiki, Etsuko Kimura, Ting Zhou, Tadahiro Ozawa, Motokazu Nakayama, Naofumi Shigemune, Kanami Shimatani, Hajime Tokuda, Ken-ichi Honjoh  Specific inhibition of cytotoxicity of Shiga-like toxin 1 of enterohemorrhagic Escherichia coli by gallocatechin gallate and epigallocatechin gallate  Food Control  2014  42, 263-269    DOI: 10.1016/j.foodcont.2014.02.017
9110  Hamid Saeed Shah, Rami Al-Oweini, Ali Haider, Ulrich Kortz, Jamshed Iqbal  Cytotoxicity and Enzyme Inhibition Studies of Polyoxometalates and Their Chitosan Nanoassemblies  Toxicol Rep  2014  1, 341-352  PubMed ID: 28962250   DOI: 10.1016/j.toxrep.2014.06.001
9098  Shinichi Esaki, Fumi Goshima, Hiroshi Kimura, Shingo Murakami, Yukihiro Nishiyama  Enhanced Antitumoral Activity of Oncolytic Herpes Simplex Virus With Gemcitabine Using Colorectal Tumor Models  Int J Cancer  2013  132 (7), 1592-601  PubMed ID: 22949155   DOI: 10.1002/ijc.27823
9102  Toshiaki Tsuji, Mikihito Nakamori, Makoto Iwahashi, Masaki Nakamura, Toshiyasu Ojima, Takeshi Iida, Masahiro Katsuda, Keiji Hayata, Yasushi Ino, Tomoki Todo, Hiroki Yamaue  An Armed Oncolytic Herpes Simplex Virus Expressing thrombospondin-1 Has an Enhanced in Vivo Antitumor Effect Against Human Gastric Cancer  Int J Cancer  2013  132 (2), 485-94  PubMed ID: 22729516   DOI: 10.1002/ijc.27681
9084  Zhuan Li, Yohei Yamauchi, Maki Kamakura, Tsugiya Murayama, Fumi Goshima, Hiroshi Kimura, Yukihiro Nishiyama  Herpes Simplex Virus Requires poly(ADP-ribose) Polymerase Activity for Efficient Replication and Induces Extracellular Signal-Related Kinase-Dependent Phosphorylation and ICP0-dependent Nuclear Localization of Tankyrase 1  J Virol  2012  86 (1), 492-503  PubMed ID: 22013039   DOI: 10.1128/JVI.05897-11
9086  Yoshifumi Muto, Fumi Goshima, Yoko Ushijima, Hiroshi Kimura, Yukihiro Nishiyama  Generation and Characterization of UL21-Null Herpes Simplex Virus Type 1  Front Microbiol  2012  3, 394  PubMed ID: 23162546   DOI: 10.3389/fmicb.2012.00394
8049  Nagahama M, Ohkubo A, Oda M, Kobayashi K, Amimoto K, Miyamoto K, Sakurai J.  Clostridium perfringens TpeL glycosylates the Rac and Ras subfamily proteins.  Infect. Immun.  2011  79:905-10  PubMed ID: 21098103   DOI: 10.1128/IAI.01019-10
8106  Fujiwara S, Nawa A, Luo C, Kamakura M, Goshima F, Kondo C, Kiyono T, Kikkawa F, Nishiyama Y.  Carrier cell-based delivery of replication-competent HSV-1 mutants enhances antitumor effect for ovarian cancer.  Cancer Gene Ther.  2011  18:77-86  PubMed ID: 20885447   DOI: 10.1038/cgt.2010.53
9083  Masahiro Nagahama, Mariko Umezaki, Masataka Oda, Keiko Kobayashi, Shigenobu Tone, Taiji Suda, Kazumi Ishidoh, Jun Sakurai  Clostridium Perfringens Iota-Toxin B Induces Rapid Cell Necrosis  Infect Immun  2011  79 (11), 4353-60  PubMed ID: 21911469   DOI: 10.1128/IAI.05677-11
9079  Manabu Shimojoh, Taku Kojima, Kohji Nakajima, Kiyoshige Hatta, Akira Katoh, Keisuke Kurita  Branched Chitins as Nonnatural Immunomodulatory Biopolymers: Secretions of TNF-alpha and NO by Direct Stimulation of Macrophages  Biomacromolecules  2010  11 (5), 1212-6  PubMed ID: 20415471   DOI: 10.1021/bm9013793
18475  Ushijima Y, Goshima F, Kimura H, Nishiyama Y.  Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions  Virol J  2009  6:168  PubMed ID: 19835589   DOI: 10.1186/1743-422X-6-168
9074  Atsushi Tanaka, Motoi Nagayoshi, Shoichiro Awata, Izumi Tanaka, Hiroshi Kusunoki  Differentiation of Human Round Spermatids Into Motile Spermatozoa Through in Vitro Coculture With Vero Cells  Reprod Med Biol  2009  8 (4), 169-175  PubMed ID: 29699323   DOI: 10.1007/s12522-009-0030-0
9076  Kohji Yamada, Yuichiro Nakatsu, Akio Onogi, Junji Ueda, Tomomasa Watanabe  Specific Intracellular Localization and Antiviral Property of Genetic and Splicing Variants in Bovine Mx1  Viral Immunol   2009  22 (6), 389-95  PubMed ID: 19951175   DOI: 10.1089/vim.2009.0050
9063  Daisuke Watanabe, Fumi Goshima, Isamu Mori, Yasuhiko Tamada, Yoshinari Matsumoto, Yukihiro Nishiyama  Oncolytic Virotherapy for Malignant Melanoma With Herpes Simplex Virus Type 1 Mutant HF10  J Dermatol Sci  2008  50 (3), 185-96  PubMed ID: 18226503   DOI: 10.1016/j.jdermsci.2007.12.001
9064  Tomohisa Kato, Atsushi Miyagawa, Maria Carmelita Z Kasuya, Ayaka Ito, Kenichi Hatanaka  Purification by Centrifugal Partition Chromatography of Amphiphilic Compounds, Glycolipids and Pseudo-Glycolipids Synthesized by Using Cells  J Chromatogr A  2008  1178 (1-2), 154-9  PubMed ID: 18082172   DOI: 10.1016/j.chroma.2007.11.094
9067  Keiko Kobayashi, Masahiro Nagahama, Noriko Ohkubo, Takashi Kojima, Hidenori Shirai, Shinobu Iwamoto, Masataka Oda, Jun Sakurai  Role of Ca2+-binding Motif in Cytotoxicity Induced by Clostridium Perfringens Iota-Toxin  Microb Pathog  2008  44 (4), 265-70  PubMed ID: 18060735   DOI: 10.1016/j.micpath.2007.10.010
9068  Yasuhiro Yamasaki, Daisuke Katsuo, Seiichiro Nakayasu, Cristina Salati, JingJing Duan, Yanan Zou, Yukihiko Matsuyama, Kenichi Yamaguchi, Tatsuya Oda  Purification and Characterization of a Novel High Molecular Weight Exotoxin Produced by Red Tide Phytoplankton, Alexandrium Tamarense  J Biochem Mol Toxicol  2008  22 (6), 405-15  PubMed ID: 19111002   DOI: 10.1002/jbt.20253
9056  S-I Kohno, C Luo, A Nawa, Y Fujimoto, D Watanabe, F Goshima, T Tsurumi, Y Nishiyama  Oncolytic Virotherapy With an HSV Amplicon Vector Expressing Granulocyte-Macrophage Colony-Stimulating Factor Using the Replication-Competent HSV Type 1 Mutant HF10 as a Helper Virus  Cancer Gene Ther  2007  14 (11), 918-26  PubMed ID: 17693992   DOI: 10.1038/sj.cgt.7701070
9059  Y-C Jung, E Mizuki, T Akao, J-C Côté  Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells  J Appl Microbiol  2007  103 (1), 65-79  PubMed ID: 17584453   DOI: 10.1111/j.1365-2672.2006.03260.x
9050  Yoko Ishikawa, Takaharu Kozakai, Hatsue Morita, Kaname Saida, Syuichi Oka, Yoshinori Masuo  Rapid Detection of Mycoplasma Contamination in Cell Cultures Using SYBR Green-based Real-Time Polymerase Chain Reaction  In Vitro Cell Dev Biol Anim  2006  42 (3-4), 63-9  PubMed ID: 16759150   DOI: 10.1290/0505035.1
9052  Reiko Tsutsumi, Shigemi Fujisaki, Masanori Shozushima, Koichi Saito, Shigehiro Sato  Anoikis-resistant MDCK Cells Carrying Susceptibilities to TNF-alpha and Verotoxin That Are Suitable for Influenza Virus Cultivation  Cytotechnology  2006  52 (2), 71-85  PubMed ID: 19002866   DOI: 10.1007/s10616-006-9032-5
3168  Mizuta K, Abiko C, Murata T, Matsuzaki Y, Itagaki T, Sanjoh K, Sakamoto M, Hongo S, Murayama S, Hayasaka K  Frequent Importation of Enterovirus 71 from Surrounding Countries into the Local Community of Yamagata, Japan, between 1998 and 2003.  J Clin Microbiol  2005  43:6171-5  PubMed ID: 16333123   DOI: 10.1128/JCM.43.12.6171-6175.2005
3413  Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio  Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.  J Biochem  2005  138:663-72  PubMed ID: 16428294   DOI: 10.1093/jb/mvi177
2892  Katayama H, Yokota H, Akao T, Nakamura O, Ohba M, Mekada E, Mizuki E  Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis  J Biochem (Tokyo)  2005  137:17-25  PubMed ID: 15713879   DOI: 10.1093/jb/mvi003
9046  Shin-ichi Kohno 1, Chenhong Luo, Fumi Goshima, Yukihiro Nishiyama, Tetsutaro Sata, Yoshinari Ono  Herpes Simplex Virus Type 1 Mutant HF10 Oncolytic Viral Therapy for Bladder Cancer  Urology  2005  66 (5), 1116-21  PubMed ID: 16286150   DOI: 10.1016/j.urology.2005.05.041
9047  Takuji Nakashima, Tadashi Tamura, Maki Kurachi, Kenichi Yamaguchi, Tatsuya Oda  Apoptosis-mediated Cytotoxicity of Prodigiosin-Like Red Pigment Produced by gamma-Proteobacterium and Its Multiple Bioactivities  Biol Pharm Bull  2005  28 (12), 2289-95  PubMed ID: 16327167   DOI: 10.1248/bpb.28.2289
9048  Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye  Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines  J Agric Food Chem  2005  53 (16), 6313-8  PubMed ID: 16076112   DOI: 10.1021/jf0506129
3003  Nakajima K, Hirose H, Taniguchi M, Kurashina H, Arasaki K, Nagahama M, Tani K, Yamamoto A, Tagaya M  Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.  EMBO J  2004  23:3216-26  PubMed ID: 15272311   DOI: 10.1038/sj.emboj.7600333
3361  Teshigahara, Osamu, Goshima, Fumi, Takao, Kazumasa, Kohno, Shin-ichi, Kimata, Hideto, Nakao, Akimasa, Nishiyama, Yukihiro  Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 10.  J Surg Oncol  2004  85:42-7  PubMed ID: 14696086   DOI: 10.1002/jso.20005
3042  Shimizu, Takeshi, Hamabata, Takashi, Yoshiki, Akemi, Hori, Takeya, Ito, Satoru, Takeda, Yoshifumi, Hayashi, Hideo  An association of 27- and 40-kDa molecules with glycolipids that bind A-B bacterial enterotoxins to cultured cells.  Biochim Biophys Acta  2003  1612:186-94  PubMed ID: 12787937   DOI: 10.1016/s0005-2736(03)00130-5
9037  Atsushi Tanaka, Motoki Nagayoshi, Shoichiro Awata, Yoshifumi Mawatari, Izumi Tanaka, Hiroshi Kusunoki  Completion of Meiosis in Human Primary Spermatocytes Through in Vitro Coculture With Vero Cells  Fertil Steril  2003  79 Suppl 1, 795-801  PubMed ID: 12620493   DOI: 10.1016/s0015-0282(02)04833-1
9038  Masahiro Nagahama, Shinya Hayashi, Shinsuke Morimitsu, Jun Sakurai  Biological Activities and Pore Formation of Clostridium Perfringens Beta Toxin in HL 60 Cells  J Biol Chem  2003  278 (38), 36934-41  PubMed ID: 12851396   DOI: 10.1074/jbc.M306562200
3037  Nakajima K, Sonoda H, Mizoguchi T, Aoki J, Arai H, Nagahama M, Tagaya M, Tani K  A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125.  J Biol Chem  2002  277:11329-35  PubMed ID: 11788596   DOI: 10.1074/jbc.M111092200
9034  Masayuki Saijo, Tatsuo Suzutani, Erik De Clercq, Masahiro Niikura, Akihiko Maeda, Shigeru Morikawa, Ichiro Kurane  Genotypic and Phenotypic Characterization of the Thymidine Kinase of ACV-resistant HSV-1 Derived From an Acyclovir-Sensitive Herpes Simplex Virus Type 1 Strain  Antiviral Res  2002  56 (3), 253-62  PubMed ID: 12406508   DOI: 10.1016/s0166-3542(02)00131-6
9028  M Ogasawara, T Suzutani, I Yoshida, M Azuma  Role of the UL25 Gene Product in Packaging DNA Into the Herpes Simplex Virus Capsid: Location of UL25 Product in the Capsid and Demonstration That It Binds DNA  J Virol  2001  75 (3), 1427-36  PubMed ID: 11152516   DOI: 10.1128/JVI.75.3.1427-1436.2001
3008  Mizoguchi T, Nakajima K, Hatsuzawa K, Nagahama M, Hauri HP, Tagaya M, Tani K  Determination of functional regions of p125, a novel mammalian Sec23p-interacting protein  Biochem Cell Biol  2000  279:144-149  PubMed ID: 11112430   DOI: 10.1006/bbrc.2000.3846
2432  Shibata I, Tsuda T, Mori M, Ono M, Sueyoshi M, Uruno K  Isolation of porcine epidemic diarrhea virus in porcine cell cultures and experimental infection of pigs of different ages.  Vet Microbiol  2000  72:173-82  PubMed ID: 10727829   DOI: 10.1016/s0378-1135(99)00199-6
3013  Tani K, Mizoguchi T, Iwamatsu A, Hatsuzawa K, Tagaya M  p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins.  J Biol Chem  1999  274:20505-12  PubMed ID: 10400679   DOI: 10.1074/jbc.274.29.20505
3038  Tani K, Oyama Y, Hatsuzawa K, Tagaya M  Hypothetical protein KIAA0079 is a mammalian homologue of yeast Sec24p.  FEBS Lett  1999  447:247-50  PubMed ID: 10214955   DOI: 10.1016/s0014-5793(99)00303-8
6269  Kawashima H, Li YF, Watanabe N, Hirose J, Hirose M, Miyasaka M.  Identification and characterization of ligands for L-selectin in the kidney. I. Versican, a large chondroitin sulfate proteoglycan, is a ligand for L-selectin.  Int Immunol  1999  11(3):393-405  PubMed ID: 10221651   DOI: 10.1093/intimm/11.3.393
6270  木村和夫, 木村久子, 川村杉生, 中村吉宏   動物細胞のマイコプラズマ検査  Microbiol Cult Cell Dec  1999  15:59-61   
9020  Y Nagao, K Yamashiro, N Hara, Y Horisawa, K Kato, A Uemura  Oral-mucosal Administration of IFN-alpha Potentiates Immune Response in Mice  J Interferon Cytokine Res  1998  18 (9), 661-6  PubMed ID: 9781804   DOI: 10.1089/jir.1998.18.661
9017  A Tada, H Kato, K Takenaga, S Hasegawa  Transforming Growth Factor beta1 Increases the Expressions of High Molecular Weight Tropomyosin Isoforms and Vinculin and Suppresses the Transformed Phenotypes in Human Lung Carcinoma Cells  Cancer Lett  1997  121 (1), 31-7  PubMed ID: 9459171   DOI: 10.1016/s0304-3835(97)00319-4
9016  ABDUL MANAF ALI, MUHAMMAD MUKRAM MACKEEN, SALEH H. EI-SHARKAwyl , JUNAINAH A. HAMIDI, NOR HADIANI ISMAILI , FAUJAN B. H. AHMADI and NORDIN H. LAJISI  Antiviral and Cytotoxic Activities of Som.e Plants Used in Malaysian Indigenous Medicine  Pertanika J Trop Agric Sci  1996  19(2/3): 129-136   
9009  H Imamura, S Takao, T Aikou  A Modified invasion-3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium Bromide Assay for Quantitating Tumor Cell Invasion  Cancer Res  1994  54 (13), 3620-4  PubMed ID: 8012990  
9013  T Kukita, A Kukita, K Nagata, H Maeda, K Kurisu, T Watanabe, T Iijima  Novel Cell-Surface Ag Expressed on Rat Osteoclasts Regulating the Function of the Calcitonin Receptor  J Immunol  1994  153 (11), 5265-73  PubMed ID: 7963580  
1404  Ohno T, Saijo-Kurita K, Miyamoto-Eimori N, Kurose T, Aoki Y, Yosimura S  A simple method for in situ freezing of anchorage-dependent cells including rat liver parenchymal cells.  Cytotechnology  1991  5:273-7  PubMed ID: 1367380   DOI: 10.1007/BF00556297
1918  Ohno T, Wang X, Kurashima J, Saijo-Kurita K, Hirono M.  A novel Vero cell line for use as a mammalian host-vector system in serum-free medium  Cytotechnology  1991  7(3):165-72  PubMed ID: 1368119   DOI: 10.1007/BF00365927


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