CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB0001 : Vero]

細胞番号 : 細胞名
RCB0001 : Vero update : 2024/09/06

細胞特性(Comment:英)

CITES. A cell line derived from kidney of African green monkey. Susceptible to many kinds of virus. Useful for development of vaccine. Used as an indicator cell line for mycoplasma testing. Require import and export permits according to the Convention on International Trade in Endangered Species (CITES). Origin animal species details

細胞特性(日)

アフリカミドリザル腎由来細胞株。ウイルス研究やワクチン開発研究に多用されている。マイコプラズマ汚染検査用細胞としても使用されている。ワシントン条約対象細胞。

細胞特性(寄託者記述:英)

細胞特性(寄託者記述:日)

使用条件(英)

There is no restriction regarding use for basic researches. In relation to the use by for-profit entities and/or the use for profit (commercial use, patent filing, etc.), a prior written permission of the DEPOSITOR is necessary.

使用条件(日)

基礎的研究につきましては、使用制限はありません。営利機関による利用もしくは営利を目的とする利用の場合は、事前に寄託者の承諾を必要とする。

備考(英)

備考(日)

承諾者住所

提供申込書類(英)

Order Form(C-0005.pdf) Approval Form(C-0006.pdf) MTA(C-0007.pdf) MTA(C-0007p.pdf)

Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).

提供申込書類(日)

依頼書C-0001.pdf 承諾書C-0002.pdf 同意書(非営利学術目的)C-0003.pdf 同意書(営利目的)C-0003p.pdf

提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。

提供手数料

手数料とお支払いについてはこちらをご覧ください。

細胞基本情報

寄託者

Simizu, Bunsiti

樹立者

Yasumura, Y. & Kawakita, Y.

寄託日

1988

動物種

_monkey < Mammals

動物系統名

African green Origin animal species details

属名

Cercopithecus

種名

aethiops

齢

adult

採取組織

kidney

転移

細胞分類

other

初代培養日

1962

入手歴

at passage 110 from Prof. B. S850821

細胞寿命

infinite

細胞形態

epithelial-like

Cellosaurus(Expasy)

CVCL_0059

細胞培養・検査情報

寄託時情報

ロット情報

培地・試薬情報

培地・試薬一覧はこちらをご覧ください。

培養形態

Adherent cells

培地

MEM + 10% FBS

抗生物質

Free

継代方法

0.25% Trypsin

継代密度

1 : 8 split

継代・培地交換頻度

Subculture : 2 times/week

培養最適温度

37 ℃

二酸化炭素濃度

5 %

凍結培地

Medium + 10% DMSO

凍結方法

Slow freezing

マイコプラズマ/アコレプラズマ

(-)

動物種PCR

ウィルス（HIV)

(-)

アイソザイム検査

LD, NP, AST

染色体検査

54-61(50) : 54(1),56(1),58(6),59(38),60(2),61(2)

画像情報

寄託時情報

ロット情報

文献情報

Reference(英)

7件

Reference(日)

3件

利用者成果(英)

88件

利用者成果(日)

0件

ページトップへ

Reference(英)

4 Shimizu E, Shirasawa H, Kodama K, Sato T, Simizu B. Expression, regulation and polymorphism of the mxi1 genes Gene 1996 176(1-2):45-8 PubMed ID: 8918230 DOI: 10.1016/0378-1119(96)00206-5

966 Simizu, B. and Terasima, T. (eds) Vero Cells - Origin, Properties and Biomedical Applications Vero Cells - Origin, Properties and Biomedical Applications. 1988 1-234

937 Sorimachi K, Yasumura Y. The autorelease of alkaline phosphatase from the plasma membrane during the incubation of cultured liver cell homogenates J Biochem 1988 103(1):195-200 PubMed ID: 3360760 DOI: 10.1093/oxfordjournals.jbchem.a122231

361 Rhim, J S, Schell K, Creasy B, Case W Biological characteristics and viral susceptibility of an African green monkey kidney cell line (Vero). Proc Soc Exp Biol Med 1969 132:670-8 PubMed ID: 4982209 DOI: 10.3181/00379727-132-34285

3 Rhim JS, Simizu B, Wiebenga NH. Multiplication of Machupo virus, the etiological agent of Bolivian hemorrhagic fever, in cell cultures Proc Soc Exp Biol Med 1969 130(2):382-7 PubMed ID: 5765269 DOI: 10.3181/00379727-130-33560

1 Simizu B, Rhim JS, Wiebenga NH. Characterization of the Tacaribe group of arboviruses. I. Propagation and plaque assay of Tacaribe virus in a line of African green monkey kidney cells (Vero) Proc Soc Exp Biol Med 1967 125(1):119-23 PubMed ID: 6027511 DOI: 10.3181/00379727-125-32029

2 Rhim JS, Simizu B, Wiebenga NH. Growth of Junin virus, the etiological agent of Argentinian hemorrhagic fever, in cell cultures Arch Gesamte Virusforsch 1967 21(2):243-5 PubMed ID: 5591575 DOI: 10.1007/BF01241448

ページトップへ

Reference(日)

1710 安村美博 アフリカミドリザル : Vero 生体の科学 1992 43:402-403

359 Ito, H. et al アフリカミドリザル腎細胞由来ー株細胞 Vero 組織培養 1981 7:43294

360 Yasumura, Y. et al 組織培養によるSV40の研究　--- ガラス器内における癌研究の予備段階 --- 日本臨床 1963 21:175-179

ページトップへ

利用者成果(英)

19797 Kurosawa M, Kato F, Hishiki T, Ito S, Fujisawa H, Yamaguchi T, Moriguchi M, Hosokawa K, Watanabe T, Saito-Tarashima N, Minakawa N, Fujimuro M. Sofosbuvir Suppresses the Genome Replication of DENV1 in Human Hepatic Huh7 Cells Int J Mol Sci 2024 25(4):2022 PubMed ID: 38396699 DOI: 10.3390/ijms25042022

22139 Ge N, Suzuki K, Sato I, Noguchi M, Nakamura Y, Matsuo-Takasaki M, Fujishiro J, Hayashi Y. Generation of human induced pluripotent stem cell lines derived from patients of cystic biliary atresia. Hum Cell 2024 38(1):18 PubMed ID: 39532815 DOI: 10.1007/s13577-024-01147-x

22164 Sibal PA, Matsumura S, Ichinose T, Bustos-Villalobos I, Morimoto D, Eissa IR, Abdelmoneim M, Aboalela MAM, Mukoyama N, Tanaka M, Naoe Y, Kasuya H. STING activator 2'3'-cGAMP enhanced HSV-1-based oncolytic viral therapy. Mol Oncol 2024 18(5):1259-1277 PubMed ID: 38400597 DOI: 10.1002/1878-0261.13603

17565 Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y. Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists iScience 2023 26(1):105742 PubMed ID: 36507221 DOI: 10.1016/j.isci.2022.105742

19773 Yuan L, Nakamichi R, Hirata Y, Matsuda A, Shinohara Y, Yamada A, Masuda Y, Honjoh KI, Miyamoto T. Mechanism for inhibition of cytotoxicity of Shiga toxin by luteolin Toxicol In Vitro 2023 87:105537 PubMed ID: 36535555 DOI: 10.1016/j.tiv.2022.105537

21334 Tashiro K, Segawa T, Futami T, Suzuki M, Itou T. Establishment and characterization of a novel kidney cell line derived from the common bottlenose dolphin. In Vitro Cell Dev Biol Anim 2023 PubMed ID: 37524977 DOI: 10.1007/s11626-023-00786-y

17638 Jimbo E, Kobayashi T, Takeshita A, Mine K, Nagafuchi S, Fukui T, Yagihashi S. Immunohistochemical detection of enteroviruses in pancreatic tissues of patients with type 1 diabetes using a polyclonal antibody against 2A protease of Coxsackievirus J Diabetes Investig 2022 13(3):435-442 PubMed ID: 34669264 DOI: 10.1111/jdi.13700

19505 Abdelmoneim M, Eissa IR, Aboalela MA, Naoe Y, Matsumura S, Sibal PA, Bustos-Villalobos I, Tanaka M, Kodera Y, Kasuya H. Metformin enhances the antitumor activity of oncolytic herpes simplex virus HF10 (canerpaturev) in a pancreatic cell cancer subcutaneous model Sci Rep 2022 12(1):21570 PubMed ID: 36513720 DOI: 10.1038/s41598-022-25065-w

20618 Shimizu T, Matsuo-Takasaki M, Luijkx D, Takami M, Arai Y, Noguchi M, Nakamura Y, Hayata T, Saito MK, Hayashi Y. Generation of human induced pluripotent stem cell lines derived from four DiGeorge syndrome patients with 22q11.2 deletion. Stem Cell Res 2022 61:102744 PubMed ID: 35292424 DOI: 10.1016/j.scr.2022.102744

20923 Isobe A, Arai Y, Kuroda D, Okumura N, Ono T, Ushiba S, Nakakita SI, Daidoji T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y. ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner. Commun Biol 2022 5(1):1188 PubMed ID: 36335195 DOI: 10.1038/s42003-022-04170-6

18099 Kato T, Nakamori M, Matsumura S, Nakamura M, Ojima T, Fukuhara H, Ino Y, Todo T, Yamaue H. Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer Oncol Lett 2021 21(6):490 PubMed ID: 33968206 DOI: 10.3892/ol.2021.12751

14066 Yada Y, Kondo T, Suga M, Tsukita K, Enami T, Shibukawa R, Sagara Y, Okanishi Y, Imamura K, Kihara T, Inoue H. Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification Stem Cell Res 2021 53:102274 PubMed ID: 33714066 DOI: 10.1016/j.scr.2021.102274

20174 Tsukamoto S, Nakade K, Wakabayashi T, Nakashima K, Takami M, Hemmi Y, Kuramochi Y, Shimizu T, Arai Y, Matsuo-Takasaki M, Noguchi M, Nakamura Y, Miwa Y, Hayashi Y. Generation of two ISL1-tdTomato reporter human induced pluripotent stem cell lines using CRISPR-Cas9 genome editing. Stem Cell Res 2021 53:102363 PubMed ID: 34087992 DOI: 10.1016/j.scr.2021.102363

20398 Ohtsuka J, Imai M, Fukumura M, Maeda M, Eguchi A, Ono R, Maemura T, Ito M, Yamayoshi S, Kataoka Y, Kawaoka Y, Nosaka T. Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2. iScience 2021 103379 PubMed ID: 34805782 DOI: 10.1016/j.isci.2021.103379

16130 Yajima S, Sugawara K, Iwai M, Tanaka M, Seto Y, Todo T. Efficacy and safety of a third-generation oncolytic herpes virus G47Δ in models of human esophageal carcinoma Mol Ther Oncolytics 2021 ;23:402-411 PubMed ID: 34853811 DOI: 10.1016/j.omto.2021.10.012

16433 Fukuchi K, Koshikawa T, Asai D, Inomata M, Sakagami H, Takemura H, Kanamoto T, Aimi H, Kikkawa Y. Lignosulfonate Rapidly Inactivates Human Immunodeficiency and Herpes Simplex Viruses Medicines (Basel) 2021 8(10):56 PubMed ID: 34677485 DOI: 10.3390/medicines8100056

16829 Yada Y, Suga M, Shibukawa R, Sagara Y, Okanishi Y, Enami T, Tsukita K, Kondo T, Imamura K, Sugihara G, Murai T, Inoue H. Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins Stem Cell Res 2021 55:102504 PubMed ID: 34419750 DOI: 10.1016/j.scr.2021.102504

16879 Kuramochi Y, Awaya T, Matsuo-Takasaki M, Takami M, An Y, Li J, Hemmi Y, Wakabayashi T, Arai Y, Inoue J, Noguchi M, Nakamura Y, Asaka I, Akimoto K, Saito MK, Hayashi Y. Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations Stem Cell Res 2021 53:102337 PubMed ID: 33901816 DOI: 10.1016/j.scr.2021.102337

9897 Yutaka Arai, Miho Takami, Yuri An, Mami Matsuo-Takasaki, Yasuko Hemmi, Tamami Wakabayashi, Jun Inoue, Michiya Noguchi, Yukio Nakamura, Keisuke Sugimoto, Tsukasa Takemura, Keisuke Okita, Kenji Osafune, Minoru Takasato, Tadayoshi Hayata, Yohei Hayashi Generation of Two Human Induced Pluripotent Stem Cell Lines Derived From Two Juvenile Nephronophthisis Patients With NPHP1 Deletion Stem Cell Res 2020 45:101815 PubMed ID: 32361464 DOI: 10.1016/j.scr.2020.101815

12341 Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H. Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration Stem Cell Res 2020 45:101787 PubMed ID: 32416577 DOI: 10.1016/j.scr.2020.101787

12344 Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H. Generation of a human induced pluripotent stem cell line, BRCi005-A, derived from a Best disease patient with BEST1 mutations Stem Cell Res 2020 45:101782 PubMed ID: 32416576 DOI: 10.1016/j.scr.2020.101782

12345 Katagami Y, Kondo T, Suga M, Yada Y, Imamura K, Shibukawa R, Sagara Y, Okanishi Y, Tsukita K, Hirayama K, Era T, Inoue H. Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a Stem Cell Res 2020 49:102095 PubMed ID: 33291009 DOI: 10.1016/j.scr.2020.102095

13613 Saito H, Murata Y, Nonaka M, Kato K. Screening of a library of traditional Chinese medicines to identify compounds and extracts which inhibit Toxoplasma gondii growth J Vet Med Sci 2020 82(2):184-187. PubMed ID: 31904004 DOI: 10.1292/jvms.19-0241

13628 Han Y, Adeyemi OS, Kabir MHB, Kato K. Screening of compound libraries for inhibitors of Toxoplasma growth and invasion Parasitol Res 2020 119(5):1675-1681 PubMed ID: 32236711 DOI: 10.1007/s00436-020-06673-9

14846 Esaki S, Goshima F, Ozaki H, Takano G, Hatano Y, Kawakita D, Ijichi K, Watanabe T, Sato Y, Murata T, Iwata H, Shibamoto Y, Murakami S, Nishiyama Y, Kimura H. Oncolytic activity of HF10 in head and neck squamous cell carcinomas Cancer Gene Ther 2020 27(7-8):585-59 PubMed ID: 31477804 DOI: 10.1038/s41417-019-0129-3

16897 Takano G, Esaki S, Goshima F, Enomoto A, Hatano Y, Ozaki H, Watanabe T, Sato Y, Kawakita D, Murakami S, Murata T, Nishiyama Y, Iwasaki S, Kimura H. Oncolytic activity of naturally attenuated herpes-simplex virus HF10 against an immunocompetent model of oral carcinoma Mol Ther Oncolytics 2020 20:220-227 PubMed ID: 33665360 DOI: 10.1016/j.omto.2020.12.007

11776 Vinh PT, Shinohara Y, Yamada A, Duc HM, Nakayama M, Ozawa T, Sato J, Masuda Y, Honjoh KI, Miyamoto T. Baicalein Inhibits Stx1 and 2 of EHE: Effects of Baicalein on the Cytotoxicity, Production, and Secretion of Shiga Toxins of Enterohaemorrhagic Escherichia coli. Toxins (Basel) 2019 PubMed ID: 31470657 DOI: 10.3390/toxins11090505

9129 Hideyuki Matsushima, Masaki Kaibori, Masahiko Hatta, Morihiko Ishizaki, Richi Nakatake, Tadayoshi Okumura, Kengo Yoshii, Tomoki Todo Efficacy of a Third-Generation Oncolytic Herpes Simplex Virus in Neuroendocrine Tumor Xenograft Models Oncotarget 2019 10 (67), 7132-7141 PubMed ID: 31903171 DOI: 10.18632/oncotarget.27391

13006 Suga M, Kondo T, Imamura K, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Enami T, Furujo M, Saijo K, Nakamura Y, Osawa M, Saito MK, Yamanaka S, Inoue H. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I. Stem Cell Res 2019 PubMed ID: 30849633 DOI: 10.1016/j.scr.2019.101406

11494 Shima T, Morikawa M, Kaneshiro J, Kambara T, Kamimura S, Yagi T, Iwamoto H, Uemura S, Shigematsu H, Shirouzu M, Ichimura T, Watanabe TM, Nitta R, Okada Y, Hirokawa N. Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport. J. Cell Biol. 2018 217(12):4164-4183 PubMed ID: 30297389 DOI: 10.1083/jcb.201711178

4370 Nakatake R, Kaibori M, Nakamura Y, Tanaka Y, Matushima H, Okumura T, Murakami T, Ino Y, Todo T, Kon M. Third-generation oncolytic herpes simplex virus inhibits the growth of liver tumors in mice. Cancer Sci. 2018 109(3):600-610 PubMed ID: 29288515 DOI: 10.1111/cas.13492

4465 Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Kajikawa J, Hiramatsu H, Sriwilaijaroen N, Ono T, Takagi T, Takahashi K, Shioda T, Matsumoto K, Suzuki Y, Nakaya T. Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells. J. Virol. 2018 92(11) PubMed ID: 29563293 DOI: 10.1128/JVI.02004-17

10268 Sato Y, Koshizuka T, Ishibashi K, Hashimoto K, Ishioka K, Ikuta K, Yokota SI, Fujii N, Suzutani T. Involvement of herpes simplex virus type 1 UL13 protein kinase in induction of SOCS genes, the negative regulators of cytokine signaling. Microbiol. Immunol. 2017 61:159-167 PubMed ID: 28419615 DOI: 10.1111/1348-0421.12483

10350 Murata Y, Sugi T, Weiss LM, Kato K. Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites. PLoS ONE 2017 12:e0178203 PubMed ID: 28609444 DOI: 10.1371/journal.pone.0178203

9121 Rui Tanaka, Fumi Goshima, Shinichi Esaki, Yoshitaka Sato, Takayuki Murata, Yukihiro Nishiyama, Daisuke Watanabe, Hiroshi Kimura The Efficacy of Combination Therapy With Oncolytic Herpes Simplex Virus HF10 and Dacarbazine in a Mouse Melanoma Model Am J Cancer Res 2017 7 (8), 1693-1703 PubMed ID: 28861325

9872 Liu W, Al-Oweini R, Meadows K, Bassil BS, Lin Z, Christian JH, Dalal NS, Bossoh AM, Mbomekallé IM, de Oliveira P, Iqbal J, Kortz U. CrIII-Substituted Heteropoly-16-Tungstates [CrIII2(B-β-XIVW8O31)2]14- (X = Si, Ge): Magnetic, Biological, and Electrochemical Studies. Inorg Chem 2016 55:10936-10946 PubMed ID: 27768287 DOI: 10.1021/acs.inorgchem.6b01458

9117 Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masaya Takehara, Masahiro Nagahama Clostridium Perfringens Delta-Toxin Induces Rapid Cell Necrosis PLoS One 2016 11 (1), e0147957 PubMed ID: 26807591 DOI: 10.1371/journal.pone.0147957

9115 Muhammad Ali Hashmi, Hamid Saeed Shah, Afsar Khan, Umar Farooq, Jamshed Iqbal, Viqar Uddin Ahmad and Shagufta Perveen Anticancer and Alkaline Phosphatase Inhibitory Effects of Compounds Isolated from the Leaves of Olea ferruginea Royle Rec Nat Prod 2015 9: 164-168

9104 Fumi Goshima, Shinichi Esaki, Chenhong Luo, Maki Kamakura, Hiroshi Kimura, Yukihiro Nishiyama Oncolytic Viral Therapy With a Combination of HF10, a Herpes Simplex Virus Type 1 Variant and Granulocyte-Macrophage Colony-Stimulating Factor for Murine Ovarian Cancer Int J Cancer 2014 134 (12), 2865-77 PubMed ID: 24265099 DOI: 10.1002/ijc.28631

9105 Takahisa Miyamoto, Seiyo Toyofuku, Narumi Tachiki, Etsuko Kimura, Ting Zhou, Tadahiro Ozawa, Motokazu Nakayama, Naofumi Shigemune, Kanami Shimatani, Hajime Tokuda, Ken-ichi Honjoh Specific inhibition of cytotoxicity of Shiga-like toxin 1 of enterohemorrhagic Escherichia coli by gallocatechin gallate and epigallocatechin gallate Food Control 2014 42, 263-269 DOI: 10.1016/j.foodcont.2014.02.017

9110 Hamid Saeed Shah, Rami Al-Oweini, Ali Haider, Ulrich Kortz, Jamshed Iqbal Cytotoxicity and Enzyme Inhibition Studies of Polyoxometalates and Their Chitosan Nanoassemblies Toxicol Rep 2014 1, 341-352 PubMed ID: 28962250 DOI: 10.1016/j.toxrep.2014.06.001

9098 Shinichi Esaki, Fumi Goshima, Hiroshi Kimura, Shingo Murakami, Yukihiro Nishiyama Enhanced Antitumoral Activity of Oncolytic Herpes Simplex Virus With Gemcitabine Using Colorectal Tumor Models Int J Cancer 2013 132 (7), 1592-601 PubMed ID: 22949155 DOI: 10.1002/ijc.27823

9102 Toshiaki Tsuji, Mikihito Nakamori, Makoto Iwahashi, Masaki Nakamura, Toshiyasu Ojima, Takeshi Iida, Masahiro Katsuda, Keiji Hayata, Yasushi Ino, Tomoki Todo, Hiroki Yamaue An Armed Oncolytic Herpes Simplex Virus Expressing thrombospondin-1 Has an Enhanced in Vivo Antitumor Effect Against Human Gastric Cancer Int J Cancer 2013 132 (2), 485-94 PubMed ID: 22729516 DOI: 10.1002/ijc.27681

9084 Zhuan Li, Yohei Yamauchi, Maki Kamakura, Tsugiya Murayama, Fumi Goshima, Hiroshi Kimura, Yukihiro Nishiyama Herpes Simplex Virus Requires poly(ADP-ribose) Polymerase Activity for Efficient Replication and Induces Extracellular Signal-Related Kinase-Dependent Phosphorylation and ICP0-dependent Nuclear Localization of Tankyrase 1 J Virol 2012 86 (1), 492-503 PubMed ID: 22013039 DOI: 10.1128/JVI.05897-11

9086 Yoshifumi Muto, Fumi Goshima, Yoko Ushijima, Hiroshi Kimura, Yukihiro Nishiyama Generation and Characterization of UL21-Null Herpes Simplex Virus Type 1 Front Microbiol 2012 3, 394 PubMed ID: 23162546 DOI: 10.3389/fmicb.2012.00394

8049 Nagahama M, Ohkubo A, Oda M, Kobayashi K, Amimoto K, Miyamoto K, Sakurai J. Clostridium perfringens TpeL glycosylates the Rac and Ras subfamily proteins. Infect. Immun. 2011 79:905-10 PubMed ID: 21098103 DOI: 10.1128/IAI.01019-10

8106 Fujiwara S, Nawa A, Luo C, Kamakura M, Goshima F, Kondo C, Kiyono T, Kikkawa F, Nishiyama Y. Carrier cell-based delivery of replication-competent HSV-1 mutants enhances antitumor effect for ovarian cancer. Cancer Gene Ther. 2011 18:77-86 PubMed ID: 20885447 DOI: 10.1038/cgt.2010.53

9083 Masahiro Nagahama, Mariko Umezaki, Masataka Oda, Keiko Kobayashi, Shigenobu Tone, Taiji Suda, Kazumi Ishidoh, Jun Sakurai Clostridium Perfringens Iota-Toxin B Induces Rapid Cell Necrosis Infect Immun 2011 79 (11), 4353-60 PubMed ID: 21911469 DOI: 10.1128/IAI.05677-11

9079 Manabu Shimojoh, Taku Kojima, Kohji Nakajima, Kiyoshige Hatta, Akira Katoh, Keisuke Kurita Branched Chitins as Nonnatural Immunomodulatory Biopolymers: Secretions of TNF-alpha and NO by Direct Stimulation of Macrophages Biomacromolecules 2010 11 (5), 1212-6 PubMed ID: 20415471 DOI: 10.1021/bm9013793

18475 Ushijima Y, Goshima F, Kimura H, Nishiyama Y. Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions Virol J 2009 6:168 PubMed ID: 19835589 DOI: 10.1186/1743-422X-6-168

9074 Atsushi Tanaka, Motoi Nagayoshi, Shoichiro Awata, Izumi Tanaka, Hiroshi Kusunoki Differentiation of Human Round Spermatids Into Motile Spermatozoa Through in Vitro Coculture With Vero Cells Reprod Med Biol 2009 8 (4), 169-175 PubMed ID: 29699323 DOI: 10.1007/s12522-009-0030-0

9076 Kohji Yamada, Yuichiro Nakatsu, Akio Onogi, Junji Ueda, Tomomasa Watanabe Specific Intracellular Localization and Antiviral Property of Genetic and Splicing Variants in Bovine Mx1 Viral Immunol 2009 22 (6), 389-95 PubMed ID: 19951175 DOI: 10.1089/vim.2009.0050

9063 Daisuke Watanabe, Fumi Goshima, Isamu Mori, Yasuhiko Tamada, Yoshinari Matsumoto, Yukihiro Nishiyama Oncolytic Virotherapy for Malignant Melanoma With Herpes Simplex Virus Type 1 Mutant HF10 J Dermatol Sci 2008 50 (3), 185-96 PubMed ID: 18226503 DOI: 10.1016/j.jdermsci.2007.12.001

9064 Tomohisa Kato, Atsushi Miyagawa, Maria Carmelita Z Kasuya, Ayaka Ito, Kenichi Hatanaka Purification by Centrifugal Partition Chromatography of Amphiphilic Compounds, Glycolipids and Pseudo-Glycolipids Synthesized by Using Cells J Chromatogr A 2008 1178 (1-2), 154-9 PubMed ID: 18082172 DOI: 10.1016/j.chroma.2007.11.094

9067 Keiko Kobayashi, Masahiro Nagahama, Noriko Ohkubo, Takashi Kojima, Hidenori Shirai, Shinobu Iwamoto, Masataka Oda, Jun Sakurai Role of Ca2+-binding Motif in Cytotoxicity Induced by Clostridium Perfringens Iota-Toxin Microb Pathog 2008 44 (4), 265-70 PubMed ID: 18060735 DOI: 10.1016/j.micpath.2007.10.010

9068 Yasuhiro Yamasaki, Daisuke Katsuo, Seiichiro Nakayasu, Cristina Salati, JingJing Duan, Yanan Zou, Yukihiko Matsuyama, Kenichi Yamaguchi, Tatsuya Oda Purification and Characterization of a Novel High Molecular Weight Exotoxin Produced by Red Tide Phytoplankton, Alexandrium Tamarense J Biochem Mol Toxicol 2008 22 (6), 405-15 PubMed ID: 19111002 DOI: 10.1002/jbt.20253

18933 Miyagawa A, Kasuya MC, Hatanaka K. Alternative methods of globotrioside production using Vero cells: a microcarrier system procedure Chem Cent J 2007 1:26 PubMed ID: 17980049 DOI: 10.1186/1752-153X-1-26

9056 S-I Kohno, C Luo, A Nawa, Y Fujimoto, D Watanabe, F Goshima, T Tsurumi, Y Nishiyama Oncolytic Virotherapy With an HSV Amplicon Vector Expressing Granulocyte-Macrophage Colony-Stimulating Factor Using the Replication-Competent HSV Type 1 Mutant HF10 as a Helper Virus Cancer Gene Ther 2007 14 (11), 918-26 PubMed ID: 17693992 DOI: 10.1038/sj.cgt.7701070

9059 Y-C Jung, E Mizuki, T Akao, J-C Côté Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells J Appl Microbiol 2007 103 (1), 65-79 PubMed ID: 17584453 DOI: 10.1111/j.1365-2672.2006.03260.x

9050 Yoko Ishikawa, Takaharu Kozakai, Hatsue Morita, Kaname Saida, Syuichi Oka, Yoshinori Masuo Rapid Detection of Mycoplasma Contamination in Cell Cultures Using SYBR Green-based Real-Time Polymerase Chain Reaction In Vitro Cell Dev Biol Anim 2006 42 (3-4), 63-9 PubMed ID: 16759150 DOI: 10.1290/0505035.1

9052 Reiko Tsutsumi, Shigemi Fujisaki, Masanori Shozushima, Koichi Saito, Shigehiro Sato Anoikis-resistant MDCK Cells Carrying Susceptibilities to TNF-alpha and Verotoxin That Are Suitable for Influenza Virus Cultivation Cytotechnology 2006 52 (2), 71-85 PubMed ID: 19002866 DOI: 10.1007/s10616-006-9032-5

3168 Mizuta K, Abiko C, Murata T, Matsuzaki Y, Itagaki T, Sanjoh K, Sakamoto M, Hongo S, Murayama S, Hayasaka K Frequent Importation of Enterovirus 71 from Surrounding Countries into the Local Community of Yamagata, Japan, between 1998 and 2003. J Clin Microbiol 2005 43:6171-5 PubMed ID: 16333123 DOI: 10.1128/JCM.43.12.6171-6175.2005

3413 Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells. J Biochem 2005 138:663-72 PubMed ID: 16428294 DOI: 10.1093/jb/mvi177

2892 Katayama H, Yokota H, Akao T, Nakamura O, Ohba M, Mekada E, Mizuki E Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis J Biochem (Tokyo) 2005 137:17-25 PubMed ID: 15713879 DOI: 10.1093/jb/mvi003

9046 Shin-ichi Kohno 1, Chenhong Luo, Fumi Goshima, Yukihiro Nishiyama, Tetsutaro Sata, Yoshinari Ono Herpes Simplex Virus Type 1 Mutant HF10 Oncolytic Viral Therapy for Bladder Cancer Urology 2005 66 (5), 1116-21 PubMed ID: 16286150 DOI: 10.1016/j.urology.2005.05.041

9047 Takuji Nakashima, Tadashi Tamura, Maki Kurachi, Kenichi Yamaguchi, Tatsuya Oda Apoptosis-mediated Cytotoxicity of Prodigiosin-Like Red Pigment Produced by gamma-Proteobacterium and Its Multiple Bioactivities Biol Pharm Bull 2005 28 (12), 2289-95 PubMed ID: 16327167 DOI: 10.1248/bpb.28.2289

9048 Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines J Agric Food Chem 2005 53 (16), 6313-8 PubMed ID: 16076112 DOI: 10.1021/jf0506129

3003 Nakajima K, Hirose H, Taniguchi M, Kurashina H, Arasaki K, Nagahama M, Tani K, Yamamoto A, Tagaya M Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. EMBO J 2004 23:3216-26 PubMed ID: 15272311 DOI: 10.1038/sj.emboj.7600333

3361 Teshigahara, Osamu, Goshima, Fumi, Takao, Kazumasa, Kohno, Shin-ichi, Kimata, Hideto, Nakao, Akimasa, Nishiyama, Yukihiro Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 10. J Surg Oncol 2004 85:42-7 PubMed ID: 14696086 DOI: 10.1002/jso.20005

3042 Shimizu, Takeshi, Hamabata, Takashi, Yoshiki, Akemi, Hori, Takeya, Ito, Satoru, Takeda, Yoshifumi, Hayashi, Hideo An association of 27- and 40-kDa molecules with glycolipids that bind A-B bacterial enterotoxins to cultured cells. Biochim Biophys Acta 2003 1612:186-94 PubMed ID: 12787937 DOI: 10.1016/s0005-2736(03)00130-5

9037 Atsushi Tanaka, Motoki Nagayoshi, Shoichiro Awata, Yoshifumi Mawatari, Izumi Tanaka, Hiroshi Kusunoki Completion of Meiosis in Human Primary Spermatocytes Through in Vitro Coculture With Vero Cells Fertil Steril 2003 79 Suppl 1, 795-801 PubMed ID: 12620493 DOI: 10.1016/s0015-0282(02)04833-1

9038 Masahiro Nagahama, Shinya Hayashi, Shinsuke Morimitsu, Jun Sakurai Biological Activities and Pore Formation of Clostridium Perfringens Beta Toxin in HL 60 Cells J Biol Chem 2003 278 (38), 36934-41 PubMed ID: 12851396 DOI: 10.1074/jbc.M306562200

3037 Nakajima K, Sonoda H, Mizoguchi T, Aoki J, Arai H, Nagahama M, Tagaya M, Tani K A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125. J Biol Chem 2002 277:11329-35 PubMed ID: 11788596 DOI: 10.1074/jbc.M111092200

9034 Masayuki Saijo, Tatsuo Suzutani, Erik De Clercq, Masahiro Niikura, Akihiko Maeda, Shigeru Morikawa, Ichiro Kurane Genotypic and Phenotypic Characterization of the Thymidine Kinase of ACV-resistant HSV-1 Derived From an Acyclovir-Sensitive Herpes Simplex Virus Type 1 Strain Antiviral Res 2002 56 (3), 253-62 PubMed ID: 12406508 DOI: 10.1016/s0166-3542(02)00131-6

9028 M Ogasawara, T Suzutani, I Yoshida, M Azuma Role of the UL25 Gene Product in Packaging DNA Into the Herpes Simplex Virus Capsid: Location of UL25 Product in the Capsid and Demonstration That It Binds DNA J Virol 2001 75 (3), 1427-36 PubMed ID: 11152516 DOI: 10.1128/JVI.75.3.1427-1436.2001

3008 Mizoguchi T, Nakajima K, Hatsuzawa K, Nagahama M, Hauri HP, Tagaya M, Tani K Determination of functional regions of p125, a novel mammalian Sec23p-interacting protein Biochem Cell Biol 2000 279:144-149 PubMed ID: 11112430 DOI: 10.1006/bbrc.2000.3846

2432 Shibata I, Tsuda T, Mori M, Ono M, Sueyoshi M, Uruno K Isolation of porcine epidemic diarrhea virus in porcine cell cultures and experimental infection of pigs of different ages. Vet Microbiol 2000 72:173-82 PubMed ID: 10727829 DOI: 10.1016/s0378-1135(99)00199-6

3013 Tani K, Mizoguchi T, Iwamatsu A, Hatsuzawa K, Tagaya M p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins. J Biol Chem 1999 274:20505-12 PubMed ID: 10400679 DOI: 10.1074/jbc.274.29.20505

3038 Tani K, Oyama Y, Hatsuzawa K, Tagaya M Hypothetical protein KIAA0079 is a mammalian homologue of yeast Sec24p. FEBS Lett 1999 447:247-50 PubMed ID: 10214955 DOI: 10.1016/s0014-5793(99)00303-8

6269 Kawashima H, Li YF, Watanabe N, Hirose J, Hirose M, Miyasaka M. Identification and characterization of ligands for L-selectin in the kidney. I. Versican, a large chondroitin sulfate proteoglycan, is a ligand for L-selectin. Int Immunol 1999 11(3):393-405 PubMed ID: 10221651 DOI: 10.1093/intimm/11.3.393

6270 木村和夫，木村久子，川村杉生，中村吉宏 動物細胞のマイコプラズマ検査 Microbiol Cult Cell Dec 1999 15:59-61

9020 Y Nagao, K Yamashiro, N Hara, Y Horisawa, K Kato, A Uemura Oral-mucosal Administration of IFN-alpha Potentiates Immune Response in Mice J Interferon Cytokine Res 1998 18 (9), 661-6 PubMed ID: 9781804 DOI: 10.1089/jir.1998.18.661

9017 A Tada, H Kato, K Takenaga, S Hasegawa Transforming Growth Factor beta1 Increases the Expressions of High Molecular Weight Tropomyosin Isoforms and Vinculin and Suppresses the Transformed Phenotypes in Human Lung Carcinoma Cells Cancer Lett 1997 121 (1), 31-7 PubMed ID: 9459171 DOI: 10.1016/s0304-3835(97)00319-4

9016 ABDUL MANAF ALI, MUHAMMAD MUKRAM MACKEEN, SALEH H. EI-SHARKAwyl , JUNAINAH A. HAMIDI, NOR HADIANI ISMAILI , FAUJAN B. H. AHMADI and NORDIN H. LAJISI Antiviral and Cytotoxic Activities of Som.e Plants Used in Malaysian Indigenous Medicine Pertanika J Trop Agric Sci 1996 19(2/3): 129-136

9009 H Imamura, S Takao, T Aikou A Modified invasion-3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium Bromide Assay for Quantitating Tumor Cell Invasion Cancer Res 1994 54 (13), 3620-4 PubMed ID: 8012990

9013 T Kukita, A Kukita, K Nagata, H Maeda, K Kurisu, T Watanabe, T Iijima Novel Cell-Surface Ag Expressed on Rat Osteoclasts Regulating the Function of the Calcitonin Receptor J Immunol 1994 153 (11), 5265-73 PubMed ID: 7963580

1404 Ohno T, Saijo-Kurita K, Miyamoto-Eimori N, Kurose T, Aoki Y, Yosimura S A simple method for in situ freezing of anchorage-dependent cells including rat liver parenchymal cells. Cytotechnology 1991 5:273-7 PubMed ID: 1367380 DOI: 10.1007/BF00556297

1918 Ohno T, Wang X, Kurashima J, Saijo-Kurita K, Hirono M. A novel Vero cell line for use as a mammalian host-vector system in serum-free medium Cytotechnology 1991 7(3):165-72 PubMed ID: 1368119 DOI: 10.1007/BF00365927

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