Cell No. : Cell Name HPS4887 :  update : 2023/03/08
Comment			Currently not ready. Disease specific iPS cell line derived from a patient : Arrhythmogenic right ventricular cardiomyopathy. Genome-edited iPS cell line.
Comment from the depositor			Disease-specific iPS cells. iPS cells were established from the peripheral blood mononuclear cells of arrhythmogenic right ventricular cardiomyopathy patient using Sendai virus vectors encoding OCT3/4, SOX2, KLF4, L-MYC.
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			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
	Basic information	Expected time	Upon a request we will start preparation. Contact us: cellips.brc@riken.jp
Reference information		Reference	1
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Reference

15948  Inoue H, Nakamura S, Higo S, Shiba M, Kohama Y, Kondo T, Kameda S, Tabata T, Okuno S, Ikeda Y, Li J, Liu L, Yamazaki S, Takeda M, Ito E, Takashima S, Miyagawa S, Sawa Y, Hikoso S, Sakata Y.  Modeling reduced contractility and impaired desmosome assembly due to plakophilin-2 deficiency using isogenic iPS cell-derived cardiomyocytes  Stem Cell Reports  2022  S2213-6711(21)00655-X  PubMed ID: 35063130   DOI: 10.1016/j.stemcr.2021.12.016

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