CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [HPS0076 : 409B2]

4005 Kondo T, Imamura K, Funayama M, Tsukita K, Miyake M, Ohta A, Woltjen K, Nakagawa M, Asada T, Arai T, Kawakatsu S, Izumi Y, Kaji R, Iwata N, Inoue H. iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease. Cell Rep 2017 21:2304-2312 PubMed ID: 29166618 DOI: 10.1016/j.celrep.2017.10.109

3676 Okita K1, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka K, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S. A more efficient method to generate integration-free human iPS cells. Nat Methods 2011 8(5):409-12 PubMed ID: 21460823 DOI: 10.1038/nmeth.1591

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22413 Duenki T, Ikeuchi Y. Insulative Compression of Neuronal Tissues on Microelectrode Arrays by Perfluorodecalin Enhances Electrophysiological Measurements. Adv Healthc Mater 2025 e2403771 PubMed ID: 39757474 DOI: 10.1002/adhm.202403771

22484 Kondo T, Thaweesapphithak S, Ambo S, Otake K, Ohori-Morita Y, Mori S, Vinaikosol N, Porntaveetus T, Egusa H. Fabrication of Hard Tissue Constructs from Induced Pluripotent Stem Cells for Exploring Mechanisms of Hereditary Tooth/Skeletal Dysplasia. Int J Mol Sci 2025 26(2) PubMed ID: 39859513 DOI: 10.3390/ijms26020804

22822 Nishie T, Taya T, Omori S, Ueno K, Okamoto Y, Higaki S, Oka M, Mitsuishi Y, Tanaka T, Nakamoto M, Kawahara H, Teraguchi N, Kotaka T, Sawabe M, Takahashi M, Kitaike S, Wada M, Iida K, Yamashita A, Jinno H, Ichimura A, Tooyama I, Sakai N, Hibi M, Hirasawa A, Takada T. Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: a Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos. Environ Health Perspect 2025 PubMed ID: 40359302 DOI: 10.1289/EHP15574

21546 Kuroda T, Yasuda S, Matsuyama S, Miura T, Sawada R, Matsuyama A, Yamamoto Y, Morioka MS, Kawaji H, Kasukawa T, Itoh M, Akutsu H, Kawai J, Sato Y. ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons. Sci Rep 2024 14(1):690 PubMed ID: 38184695 DOI: 10.1038/s41598-023-51082-4

21673 Osaki T, Duenki T, Chow SYA, Ikegami Y, Beaubois R, Levi T, Nakagawa-Tamagawa N, Hirano Y, Ikeuchi Y. Complex activity and short-term plasticity of human cerebral organoids reciprocally connected with axons. Nat Commun 2024 15(1):2945 PubMed ID: 38600094 DOI: 10.1038/s41467-024-46787-7

21811 Zenk F, Fleck JS, Jansen SMJ, Kashanian B, Eisinger B, Santel M, Dupré JS, Camp JG, Treutlein B. Single-cell epigenomic reconstruction of developmental trajectories from pluripotency in human neural organoid systems. Nat Neurosci 2024 PubMed ID: 38914828 DOI: 10.1038/s41593-024-01652-0

21955 Tomuro K, Mito M, Toh H, Kawamoto N, Miyake T, Chow SYA, Doi M, Ikeuchi Y, Shichino Y, Iwasaki S. Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts. Nat Commun 2024 15(1):7061 PubMed ID: 39187487 DOI: 10.1038/s41467-024-51258-0

22087 Niwa R, Matsumoto T, Liu AY, Kawato M, Kondo T, Tsukita K, Gee P, Inoue H, Maurissen TL, Woltjen K. Enrichment of Allelic Editing Outcomes by Prime Editing in Induced Pluripotent Stem Cells. CRISPR J 2024 7(5):293-304 PubMed ID: 39436282 DOI: 10.1089/crispr.2024.0028

22382 Beaubois R, Cheslet J, Duenki T, De Venuto G, Carè M, Khoyratee F, Chiappalone M, Branchereau P, Ikeuchi Y, Levi T. BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network Nat Commun 2024 15(1):5142 PubMed ID: 38902236 DOI: 10.1038/s41467-024-48905-x

19744 Azuma N, Yokoi T, Tanaka T, Matsuzaka E, Saida Y, Nishina S, Terao M, Takada S, Fukami M, Okamura K, Maehara K, Yamasaki T, Hirayama J, Nishina H, Handa H, Yamaguchi Y. Integrator complex subunit 15 controls mRNA splicing and is critical for eye development Hum Mol Genet 2023 32(12):2032-2045 PubMed ID: 36851842 DOI: 10.1093/hmg/ddad034

19819 Zhang D, Eguchi N, Okazaki S, Sora I, Hishimoto A. Telencephalon Organoids Derived from an Individual with ADHD Show Altered Neurodevelopment of Early Cortical Layer Structure Stem Cell Rev Rep 2023 19(5):1482-1491 PubMed ID: 36872412 DOI: 10.1007/s12015-023-10519-z

17483 Nakatsu D, Kunishige R, Taguchi Y, Shinozaki-Narikawa N, Osaka K, Yokomizo K, Ishida M, Takei S, Yamasaki S, Hagiya K, Hattori K, Tsukamoto T, Murata M, Kano F. BMP4-SMAD1/5/9-RUNX2 pathway activation inhibits neurogenesis and oligodendrogenesis in Alzheimer's patients' iPSCs in senescence-related conditions Stem Cell Reports 2023 18(3):688-705 PubMed ID: 36764297 DOI: 10.1016/j.stemcr.2023.01.004

21125 Togo H, Terada K, Ujitsugu A, Hirose Y, Takeuchi H, Kusunoki M. Fabrication Scaffold with High Dimensional Control for Spheroids with Undifferentiated iPS Cell Properties. Cells 2023 12(2) PubMed ID: 36672213 DOI: 10.3390/cells12020278

21170 Kawamata M, Suzuki HI, Kimura R, Suzuki A. Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs. Nat Biomed Eng 2023 PubMed ID: 37037965 DOI: 10.1038/s41551-023-01011-7

21329 Riesenberg S, Kanis P, Macak D, Wollny D, Düsterhöft D, Kowalewski J, Helmbrecht N, Maricic T, Pääbo S. Efficient high-precision homology-directed repair-dependent genome editing by HDRobust. Nat Methods 2023 PubMed ID: 37474806 DOI: 10.1038/s41592-023-01949-1

21371 Bressan C, Snapyan M, Snapyan M, Klaus J, di Matteo F, Robertson SP, Treutlein B, Parent M, Cappello S, Saghatelyan A. Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia. EMBO Mol Med 2023 e16908 PubMed ID: 37609821 DOI: 10.15252/emmm.202216908

21439 Terada E, Bamba Y, Takagaki M, Kawabata S, Tachi T, Nakamura H, Nishida T, Kishima H. Silicate Microfiber Scaffolds Support the Formation and Expansion of the Cortical Neuronal Layer of Cerebral Organoids With a Sheet-Like Configuration. Stem Cells Transl Med 2023 PubMed ID: 37843388 DOI: 10.1093/stcltm/szad066

17541 He Z, Maynard A, Jain A, Gerber T, Petri R, Lin HC, Santel M, Ly K, Dupré JS, Sidow L, Sanchis Calleja F, Jansen SMJ, Riesenberg S, Camp JG, Treutlein B. Lineage recording in human cerebral organoids Nat Methods 2022 19(1):90-99 PubMed ID: 34969984 DOI: 10.1038/s41592-021-01344-8

17579 Hirata M, Ichiyanagi T, Katoh H, Hashimoto T, Suzuki H, Nitta H, Kawase M, Nakai R, Imamura M, Ichiyanagi K. Sequence divergence and retrotransposon insertion underlie interspecific epigenetic differences in primates Mol Biol Evol 2022 39(10):msac208 PubMed ID: 36219870 DOI: 10.1093/molbev/msac208

20238 Linda K, Lewerissa EI, Verboven AHA, Gabriele M, Frega M, Klein Gunnewiek TM, Devilee L, Ulferts E, Hommersom M, Oudakker A, Schoenmaker C, van Bokhoven H, Schubert D, Testa G, Koolen DA, de Vries BBA, Nadif Kasri N. Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders. Autophagy 2022 1-20 PubMed ID: 34286667 DOI: 10.1080/15548627.2021.1936777

16702 Song D, Takahashi G, Zheng YW, Matsuo-Takasaki M, Li J, Takami M, An Y, Hemmi Y, Miharada N, Fujioka T, Noguchi M, Nakajima T, Saito MK, Nakamura Y, Oda T, Miyaoka Y, Hayashi Y. Retinoids rescue ceruloplasmin secretion and alleviate oxidative stress in Wilson's disease-specific hepatocytes Hum Mol Genet 2022 Apr 7;ddac080 PubMed ID: 35388883 DOI: 10.1093/hmg/ddac080

16844 Cruceanu C, Dony L, Krontira AC, Fischer DS, Roeh S, Di Giaimo R, Kyrousi C, Kaspar L, Arloth J, Czamara D, Gerstner N, Martinelli S, Wehner S, Breen MS, Koedel M, Sauer S, Sportelli V, Rex-Haffner M, Cappello S, Theis FJ, Binder EB. Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study Am J Psychiatry 2022 179(5):375-387 PubMed ID: 34698522 DOI: 10.1176/appi.ajp.2021.21010095

20851 Chow SYA, Nakayama K, Osaki T, Sugiyama M, Yamada M, Takeuchi H, Ikeuchi Y. Human sensory neurons modulate melanocytes through secretion of RGMB. Cell Rep 2022 40(12):111366 PubMed ID: 36130522 DOI: 10.1016/j.celrep.2022.111366

20875 Okawa R, Sogawa K, Shiozaki M, Yachiku K, Miura T, Shibata T, Ezoe S. The effects of continuous exposure to low-dose chlorine dioxide gas on the characteristics of induced pluripotent stem cells. Regen Ther 2022 21:250-257 PubMed ID: 36092508 DOI: 10.1016/j.reth.2022.07.014

20878 Fleck JS, Jansen SMJ, Wollny D, Zenk F, Seimiya M, Jain A, Okamoto R, Santel M, He Z, Camp JG, Treutlein B. Inferring and perturbing cell fate regulomes in human brain organoids. Nature 2022 PubMed ID: 36198796 DOI: 10.1038/s41586-022-05279-8

20936 Yoshida S, Kato TM, Sato Y, Umekage M, Ichisaka T, Tsukahara M, Takasu N, Yamanaka S. A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population. Med (N Y) 2022 PubMed ID: 36395757 DOI: 10.1016/j.medj.2022.10.003

18217 Polla DL, Farazi Fard MA, Tabatabaei Z, Habibzadeh P, Levchenko OA, Nikuei P, Makrythanasis P, Hussain M, von Hardenberg S, Zeinali S, Fallah MS, Schuurs-Hoeijmakers JHM, Shahzad M, Fatima F, Fatima N, Kaat LD, Bruggenwirth HT, Fleming LR, Condie J, Ploski R, Pollak A, Pilch J, Demina NA, Chukhrova AL, Sergeeva VS, Venselaar H, Masri AT, Hamamy H, Santoni FA, Linda K, Ahmed ZM, Nadif Kasri N, de Brouwer APM, Bergmann AK, Hethey S, Yavarian M, Ansar M, Riazuddin S, Riazuddin S, Silawi M, Ruggeri G, Pirozzi F, Eftekhar E, Taghipour Sheshdeh A, Bahramjahan S, Mirzaa GM, Lavrov AV, Antonarakis SE, Faghihi MA, van Bokhoven H. Biallelic variants in TMEM222 cause a new autosomal recessive neurodevelopmental disorder Genet Med 2021 23(7):1246-1254 PubMed ID: 33824500 DOI: 10.1038/s41436-021-01133-w

13380 Fukusumi H, Togo K, Sumida M, Nakamori M, Obika S, Baba K, Shofuda T, Ito D, Okano H, Mochizuki H, Kanemura Y. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio 2021 11(2):354-366 PubMed ID: 33301617 DOI: 10.1002/2211-5463.13060

20014 Matsuo M, Nadanaka S, Soga M, Sugiyama T, Serigano S, Shimano K, Ichinose F, Nakamura T, Maeda T, Houkin K, Era T, Kitagawa H. Vulnerability to shear stress caused by altered peri-endothelial matrix is a key feature of Moyamoya disease. Sci Rep 2021 11(1):1552 PubMed ID: 33452387 DOI: 10.1038/s41598-021-81282-9

20221 Sato M, Inohaya A, Yasuda E, Mogami H, Chigusa Y, Kawasaki K, Kawamura Y, Ueda Y, Takai H, Mandai M, Kondoh E. Three-dimensional human placenta-like bud synthesized from induced pluripotent stem cells Sci Rep 2021 11(1):14167 PubMed ID: 34239021 DOI: 10.1038/s41598-021-93766-9

20257 Lin HC, He Z, Ebert S, Schörnig M, Santel M, Nikolova MT, Weigert A, Hevers W, Kasri NN, Taverna E, Camp JG, Treutlein B. NGN2 induces diverse neuron types from human pluripotency. Stem Cell Reports 2021 PubMed ID: 34358451 DOI: 10.1016/j.stemcr.2021.07.006

15507 Koike H, Iwasawa K, Ouchi R, Maezawa M, Kimura M, Kodaka A, Nishii S, Thompson WL, Takebe T. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells Nat Protoc 2021 16(2):919-936 PubMed ID: 33432231 DOI: 10.1038/s41596-020-00441-w

15523 Abe T, Uosaki H, Shibata H, Hara H, Sarentonglaga B, Nagao Y, Hanazono Y. Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells Exp Hematol 2021 95:46-57.e8 PubMed ID: 33395577 DOI: 10.1016/j.exphem.2020.12.006

20366 Hisatsune C, Shimada T, Miyamoto A, Lee A, Yamagata K. Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca2+ Influx via L-Type Ca2+ Channels. J Neurosci 2021 41(39):8134-8149 PubMed ID: 34417327 DOI: 10.1523/JNEUROSCI.1930-20.2021

15683 Vita Stepanova, Kaja Ewa Moczulska, Guido N Vacano, Ilia Kurochkin, Xiangchun Ju, Stephan Riesenberg, Dominik Macak, Tomislav Maricic, Linda Dombrowski, Maria Schörnig, Konstantinos Anastassiadis, Oliver Baker, Ronald Naumann, Ekaterina Khrameeva, Anna Vanushkina, Elena Stekolshchikova, Alina Egorova, Anna Tkachev, Randall Mazzarino, Nathan Duval, Dmitri Zubkov, Patrick Giavalisco, Terry G Wilkinson, David Patterson, Philipp Khaitovich, Svante Pääbo Reduced purine biosynthesis in humans after their divergence from Neandertals eLife 2021 10:2021-5-4 PubMed ID: 33942714 DOI: 10.7554/elife.58741

15899 Kashiwagi K, Shichino Y, Osaki T, Sakamoto A, Nishimoto M, Takahashi M, Mito M, Weber F, Ikeuchi Y, Iwasaki S, Ito T. eIF2B-capturing viral protein NSs suppresses the integrated stress response Nat Commun 2021 12(1):7102 PubMed ID: 34876589 DOI: 10.1038/s41467-021-27337-x

20491 Tadokoro S, Tokuyama-Toda R, Tatehara S, Ide S, Umeki H, Miyoshi K, Noma T, Satomura K. A New Induction Method for the Controlled Differentiation of Human-Induced Pluripotent Stem Cells Using Frozen Sections. Cells 2021 10(11) PubMed ID: 34831050 DOI: 10.3390/cells10112827

6879 Kasai T, Suga H, Sakakibara M, Ozone C, Matsumoto R, Kano M, Mitsumoto K, Ogawa K, Kodani Y, Nagasaki H, Inoshita N, Sugiyama M, Onoue T, Tsunekawa T, Ito Y, Takagi H, Hagiwara D, Iwama S, Goto M, Banno R, Takahashi J, Arima H. Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells. Cell Rep 2020 30(1):18-24 PubMed ID: 31914385 DOI: 10.1016/j.celrep.2019.12.009

10143 Tomoyo Sawada, Thomas E Chater, Yohei Sasagawa, Mika Yoshimura, Noriko Fujimori-Tonou, Kaori Tanaka, Kynon J M Benjamin, Apuã C M Paquola, Jennifer A Erwin, Yukiko Goda, Itoshi Nikaido, Tadafumi Kato Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids Mol Psychiatry 2020 25(11):2695-2711 PubMed ID: 32764691 DOI: 10.1038/s41380-020-0844-z

11989 Dayem AA, Won J, Goo HG, Yang GM, Seo DS, Jeon BM, Choi HY, Park SE, Lim KM, Jang SH, Lee SB, Choi SB, Kim K, Kang GH, Yeon GB, Kim DS, Cho SG. The immobilization of fibronectin- and fibroblast growth factor 2-derived peptides on a culture plate supports the attachment and proliferation of human pluripotent stem cells. Stem Cell Res 2020 PubMed ID: 31981882 DOI: 10.1016/j.scr.2020.101700

13010 Misawa R, Minami T, Okamoto A, Ikeuchi Y. A Light-Inducible Hedgehog Signaling Activator Modulates Proliferation and Differentiation of Neural Cells. ACS Chem Biol 2020 PubMed ID: 32343549 DOI: 10.1021/acschembio.0c00195

13064 Maurissen TL, Woltjen K. Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation. Nat Commun 2020 PubMed ID: 32513994 DOI: 10.1038/s41467-020-16643-5

13174 Yokouchi Y, Suzuki S, Ohtsuki N, Yamamoto K, Noguchi S, Soejima Y, Goto M, Ishioka K, Nakamura I, Suzuki S, Takenoshita S, Era T. Rapid repair of human disease-specific single-nucleotide variants by One-SHOT genome editing. Sci Rep 2020 PubMed ID: 32811847 DOI: 10.1038/s41598-020-70401-7

13381 Sim H, Seo JH, Kim J, Oh M, Lee JE, Baek A, Lee SY, Chung SK, Son MY, Chae JI, Jeon YJ, Kim J. Quantitative Proteomic Analysis of Primitive Neural Stem Cells from LRRK2 G2019S-Associated Parkinson's Disease Patient-Derived iPSCs. Life (Basel) 2020 PubMed ID: 33297425 DOI: 10.3390/life10120331

14062 Ayo-Martin AC, Kyrousi C, Di Giaimo R, Cappello S. GNG5 Controls the Number of Apical and Basal Progenitors and Alters Neuronal Migration During Cortical Development Front Mol Biosci 2020 578137. PubMed ID: 33330619 DOI: 10.3389/fmolb.2020.578137

14943 Krieger TG, Tirier SM, Park J, Jechow K, Eisemann T, Peterziel H, Angel P, Eils R, Conrad C. Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics Neuro Oncol 2020 22(8):1138-1149 PubMed ID: 32297954 DOI: 10.1093/neuonc/noaa091

16212 Kotaro Tsuboyama, Tatsuya Osaki, Eriko Matsuura-Suzuki, Hiroko Kozuka-Hata, Yuki Okada, Masaaki Oyama, Yoshiho Ikeuchi, Shintaro Iwasaki, Yukihide Tomari A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation PLoS Biol 2020 18(3):e3000632 PubMed ID: 32163402 DOI: 10.1371/journal.pbio.3000632

16885 Osman A, Oze M, Afify SM, Hassan G, El-Ghlban S, Nawara HM, Fu X, Zahra MH, Seno A, Winer I, Salomon DS, Seno M. Tumor-associated macrophages derived from cancer stem cells Acta Histochem 2020 122(8):151628 PubMed ID: 32992123 DOI: 10.1016/j.acthis.2020.151628

19492 Kanie K, Bando H, Iguchi G, Muguruma K, Matsumoto R, Hidaka-Takeno R, Okimura Y, Yamamoto M, Fujita Y, Fukuoka H, Yoshida K, Suda K, Nishizawa H, Ogawa W, Takahashi Y. Pathogenesis of Anti-PIT-1 Antibody Syndrome: PIT-1 Presentation by HLA Class I on Anterior Pituitary Cells J Endocr Soc 2019 3(11):1969-1978 PubMed ID: 31620667 DOI: 10.1210/js.2019-00243

11304 Ueda M, Hashimoto Y, Honda Y, Baba S, Morita S. Comparison of the characteristics of mesenchymal stem-like cells derived by integration-free induced pluripotent stem cells in different single-cell culture media under feeder-free conditions. Med Mol Morphol 2019 PubMed ID: 30446810 DOI: 10.1007/s00795-018-0211-1

4572 Kuroda T, Yasuda S, Tachi S, Matsuyama S, Kusakawa S, Tano K, Miura T, Matsuyama A, Sato Y. SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation. Nat Commun 2019 10(1):2175 PubMed ID: 31092818 DOI: 10.1038/s41467-019-09511-4

5346 Kirihara T, Luo Z, Chow SYA, Misawa R, Kawada J, Shibata S, Khoyratee F, Vollette CA, Volz V, Levi T, Fujii T, Ikeuchi Y. A Human Induced Pluripotent Stem Cell-Derived Tissue Model of a Cerebral Tract Connecting Two Cortical Regions. iScience 2019 14:301-311 PubMed ID: 31006610 DOI: 10.1016/j.isci.2019.03.012

11576 Komatsu Y, Takeuchi D, Tokunaga T, Sakurai H, Makino A, Honda T, Ikeda Y, Tomonaga K. RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs. Mol Ther Methods Clin Dev 2019 14:47-55 PubMed ID: 31309127 DOI: 10.1016/j.omtm.2019.05.010

11589 Aoki H, Yamashita M, Hashita T, Nakayama M, Yagi M, Iwao T, Matsunaga T. Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures. Biochem. Biophys. Res. Commun. 2019 515(4):672-678 PubMed ID: 31178142 DOI: 10.1016/j.bbrc.2019.05.179

11744 Riesenberg S, Chintalapati M, Macak D, Kanis P, Maricic T, Pääbo S. Simultaneous precise editing of multiple genes in human cells. Nucleic Acids Res. 2019 PubMed ID: 31392986 DOI: 10.1093/nar/gkz669

11860 Kanton S, Boyle MJ, He Z, Santel M, Weigert A, Sanchís-Calleja F, Guijarro P, Sidow L, Fleck JS, Han D, Qian Z, Heide M, Huttner WB, Khaitovich P, Pääbo S, Treutlein B, Camp JG. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature 2019 PubMed ID: 31619793 DOI: 10.1038/s41586-019-1654-9

10578 Yuki Maeda, Keiichi Motoyama, Taishi Higashi, Risako Onodera, Toru Takeo, Naomi Nakagata, Yuki Kurauchi, Hiroshi Katsuki, Yoichi Ishitsuka, Yuki Kondo, Tetsumi Irie, Takumi Era, Hidetoshi Arima Lowering effect of dimethyl-α-cyclodextrin on GM1-ganglioside accumulation in GM1-gangliosidosis model cells and in brain of β-galactosidase-knockout mice Journal of Inclusion Phenomena and Macrocyclic Chemistry 2019 93:53–66 DOI: 10.1007/s10847-018-0835-8

12368 Kimura Y, Shofuda T, Higuchi Y, Nagamori I, Oda M, Nakamori M, Onodera M, Kanematsu D, Yamamoto A, Katsuma A, Suemizu H, Nakano T, Kanemura Y, Mochizuki H. Human Genomic Safe Harbors and the Suicide Gene-Based Safeguard System for iPSC-Based Cell Therapy Stem Cells Transl Med 2019 8(7):627-638 PubMed ID: 30887735 DOI: 10.1002/sctm.18-0039

7001 Akiyama T, Sato S, Chikazawa-Nohtomi N, Soma A, Kimura H, Wakabayashi S, Ko SBH, Ko MSH. Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing. Sci Rep 2018 8:1189 PubMed ID: 29352121 DOI: 10.1038/s41598-017-19114-y

10463 Sato-Nishiuchi R, Li S, Ebisu F, Sekiguchi K. Recombinant laminin fragments endowed with collagen-binding activity: A tool for conferring laminin-like cell-adhesive activity to collagen matrices. Matrix Biol. 2018 65:75-90 PubMed ID: 28801205 DOI: 10.1016/j.matbio.2017.08.001

11234 Yasuda S, Kusakawa S, Kuroda T, Miura T, Tano K, Takada N, Matsuyama S, Matsuyama A, Nasu M, Umezawa A, Hayakawa T, Tsutsumi H, Sato Y. Tumorigenicity-associated characteristics of human iPS cell lines. PLoS ONE 2018 PubMed ID: 30286143 DOI: 10.1371/journal.pone.0205022

4124 Ikeda K, Kawasaki Y, Matsuda H, Kishida S, Iwasaki A, Ohata S, Urashima Y, Hirotani Y. Approach for differentiating trophoblast cell lineage from human induced pluripotent stem cells with retinoic acid in the absence of bone morphogenetic protein 4. Placenta 2018 PubMed ID: 30415744 DOI: 10.1016/j.placenta.2018.10.001

5348 Yoshinori Hasegawa, Masashi Ikeno, Nobutaka Suzuki, Manabu Nakayama, Osamu Ohara Improving the efficiency of gene insertion in a human artificial chromosome vector and its transfer in human-induced pluripotent stem cells Biology Methods and Protocols 2018 1–10 PubMed ID: 32161806 DOI: 10.1093/biomethods/bpy013

5777 Nakashima Y, Miyagi-Shiohira C, Noguchi H2, Omasa T. Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells. Mol Ther 2018 26(7):1715-1734 PubMed ID: 29929789 DOI: 10.1016/j.ymthe.2018.06.005

7009 Yokoi T, Tanaka T, Matsuzaka E, Tamalu F, Watanabe SI, Nishina S, Azuma N. Effects of neuroactive agents on axonal growth and pathfinding of retinal ganglion cells generated from human stem cells. Sci Rep 2017 7:16757 PubMed ID: 29196712 DOI: 10.1038/s41598-017-16727-1

7015 Kawada J, Kaneda S, Kirihara T, Maroof A, Levi T, Eggan K, Fujii T, Ikeuchi Y. Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons. Stem Cell Reports 2017 9:1441-1449 PubMed ID: 29107592 DOI: 10.1016/j.stemcr.2017.09.021

7026 Koui Y, Kido T, Ito T, Oyama H, Chen SW, Katou Y, Shirahige K, Miyajima A. An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells. Stem Cell Reports 2017 9:490-498 PubMed ID: 28757162 DOI: 10.1016/j.stemcr.2017.06.010

7031 Ikeda K, Nagata S, Okitsu T, Takeuchi S. Cell fiber-based three-dimensional culture system for highly efficient expansion of human induced pluripotent stem cells. Sci Rep 2017 7:2850 PubMed ID: 28588295 DOI: 10.1038/s41598-017-03246-2

9918 Shimizu Y, Satou M, Hayashi K, Nakamura Y, Fujimaki M, Horibata Y, Ando H, Watanabe T, Shiobara T, Chibana K, Takemasa A, Sugimoto H, Anzai N, Ishii Y. Matrix-assisted laser desorption/ionization imaging mass spectrometry reveals changes of phospholipid distribution in induced pluripotent stem cell colony differentiation. Anal Bioanal Chem 2017 409:1007-1016 PubMed ID: 27815610 DOI: 10.1007/s00216-016-0015-x

10345 Zuiki M, Chiyonobu T, Yoshida M, Maeda H, Yamashita S, Kidowaki S, Hasegawa T, Gotoh H, Nomura T, Ono K, Hosoi H, Morimoto M. Luteolin attenuates interleukin-6-mediated astrogliosis in human iPSC-derived neural aggregates: A candidate preventive substance for maternal immune activation-induced abnormalities. Neurosci. Lett. 2017 653:296-301 PubMed ID: 28595950 DOI: 10.1016/j.neulet.2017.06.004

10409 Bamba Y, Kanemura Y, Okano H, Yamasaki M. Visualization of migration of human cortical neurons generated from induced pluripotent stem cells. J. Neurosci. Methods 2017 289:57-63 PubMed ID: 28694214 DOI: 10.1016/j.jneumeth.2017.07.004

5774 Miyagoe-Suzuki Y, Nishiyama T, Nakamura M, Narita A, Takemura F, Masuda S, Minami N, Murayama K, Komaki H, Goto YI, Takeda S. Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status. Stem Cells Int 2017 2017:7906843 PubMed ID: 28491099 DOI: 10.1155/2017/7906843

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