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20238
Linda K, Lewerissa EI, Verboven AHA, Gabriele M, Frega M, Klein Gunnewiek TM, Devilee L, Ulferts E, Hommersom M, Oudakker A, Schoenmaker C, van Bokhoven H, Schubert D, Testa G, Koolen DA, de Vries BBA, Nadif Kasri N.
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.
Autophagy
2022
1-20
PubMed ID: 34286667
DOI: 10.1080/15548627.2021.1936777
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16702
Song D, Takahashi G, Zheng YW, Matsuo-Takasaki M, Li J, Takami M, An Y, Hemmi Y, Miharada N, Fujioka T, Noguchi M, Nakajima T, Saito MK, Nakamura Y, Oda T, Miyaoka Y, Hayashi Y.
Retinoids rescue ceruloplasmin secretion and alleviate oxidative stress in Wilson's disease-specific hepatocytes
Hum Mol Genet
2022
Apr 7;ddac080
PubMed ID: 35388883
DOI: 10.1093/hmg/ddac080
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16844
Cruceanu C, Dony L, Krontira AC, Fischer DS, Roeh S, Di Giaimo R, Kyrousi C, Kaspar L, Arloth J, Czamara D, Gerstner N, Martinelli S, Wehner S, Breen MS, Koedel M, Sauer S, Sportelli V, Rex-Haffner M, Cappello S, Theis FJ, Binder EB.
Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study
Am J Psychiatry
2022
179(5):375-387
PubMed ID: 34698522
DOI: 10.1176/appi.ajp.2021.21010095
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20851
Chow SYA, Nakayama K, Osaki T, Sugiyama M, Yamada M, Takeuchi H, Ikeuchi Y.
Human sensory neurons modulate melanocytes through secretion of RGMB.
Cell Rep
2022
40(12):111366
PubMed ID: 36130522
DOI: 10.1016/j.celrep.2022.111366
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20875
Okawa R, Sogawa K, Shiozaki M, Yachiku K, Miura T, Shibata T, Ezoe S.
The effects of continuous exposure to low-dose chlorine dioxide gas on the characteristics of induced pluripotent stem cells.
Regen Ther
2022
21:250-257
PubMed ID: 36092508
DOI: 10.1016/j.reth.2022.07.014
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20878
Fleck JS, Jansen SMJ, Wollny D, Zenk F, Seimiya M, Jain A, Okamoto R, Santel M, He Z, Camp JG, Treutlein B.
Inferring and perturbing cell fate regulomes in human brain organoids.
Nature
2022
PubMed ID: 36198796
DOI: 10.1038/s41586-022-05279-8
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20936
Yoshida S, Kato TM, Sato Y, Umekage M, Ichisaka T, Tsukahara M, Takasu N, Yamanaka S.
A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population.
Med (N Y)
2022
PubMed ID: 36395757
DOI: 10.1016/j.medj.2022.10.003
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13380
Fukusumi H, Togo K, Sumida M, Nakamori M, Obika S, Baba K, Shofuda T, Ito D, Okano H, Mochizuki H, Kanemura Y.
Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
FEBS Open Bio
2021
11(2):354-366
PubMed ID: 33301617
DOI: 10.1002/2211-5463.13060
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20014
Matsuo M, Nadanaka S, Soga M, Sugiyama T, Serigano S, Shimano K, Ichinose F, Nakamura T, Maeda T, Houkin K, Era T, Kitagawa H.
Vulnerability to shear stress caused by altered peri-endothelial matrix is a key feature of Moyamoya disease.
Sci Rep
2021
11(1):1552
PubMed ID: 33452387
DOI: 10.1038/s41598-021-81282-9
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20221
Sato M, Inohaya A, Yasuda E, Mogami H, Chigusa Y, Kawasaki K, Kawamura Y, Ueda Y, Takai H, Mandai M, Kondoh E.
Three-dimensional human placenta-like bud synthesized from induced pluripotent stem cells
Sci Rep
2021
11(1):14167
PubMed ID: 34239021
DOI: 10.1159/000253996
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20257
Lin HC, He Z, Ebert S, Schörnig M, Santel M, Nikolova MT, Weigert A, Hevers W, Kasri NN, Taverna E, Camp JG, Treutlein B.
NGN2 induces diverse neuron types from human pluripotency.
Stem Cell Reports
2021
PubMed ID: 34358451
DOI: 10.1016/j.stemcr.2021.07.006
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15507
Koike H, Iwasawa K, Ouchi R, Maezawa M, Kimura M, Kodaka A, Nishii S, Thompson WL, Takebe T.
Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells
Nat Protoc
2021
16(2):919-936
PubMed ID: 33432231
DOI: 10.1038/s41596-020-00441-w
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15523
Abe T, Uosaki H, Shibata H, Hara H, Sarentonglaga B, Nagao Y, Hanazono Y.
Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells
Exp Hematol
2021
95:46-57.e8
PubMed ID: 33395577
DOI: 10.1016/j.exphem.2020.12.006
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20366
Hisatsune C, Shimada T, Miyamoto A, Lee A, Yamagata K.
Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca2+ Influx via L-Type Ca2+ Channels.
J Neurosci
2021
41(39):8134-8149
PubMed ID: 34417327
DOI: 10.1523/JNEUROSCI.1930-20.2021
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15683
Vita Stepanova, Kaja Ewa Moczulska, Guido N Vacano, Ilia Kurochkin, Xiangchun Ju, Stephan Riesenberg, Dominik Macak, Tomislav Maricic, Linda Dombrowski, Maria Schörnig, Konstantinos Anastassiadis, Oliver Baker, Ronald Naumann, Ekaterina Khrameeva, Anna Vanushkina, Elena Stekolshchikova, Alina Egorova, Anna Tkachev, Randall Mazzarino, Nathan Duval, Dmitri Zubkov, Patrick Giavalisco, Terry G Wilkinson, David Patterson, Philipp Khaitovich, Svante Pääbo
Reduced purine biosynthesis in humans after their divergence from Neandertals
eLife
2021
10:2021-5-4
PubMed ID: 33942714
DOI: 10.7554/elife.58741
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15899
Kashiwagi K, Shichino Y, Osaki T, Sakamoto A, Nishimoto M, Takahashi M, Mito M, Weber F, Ikeuchi Y, Iwasaki S, Ito T.
eIF2B-capturing viral protein NSs suppresses the integrated stress response
Nat Commun
2021
12(1):7102
PubMed ID: 34876589
DOI: 10.1038/s41467-021-27337-x
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20491
Tadokoro S, Tokuyama-Toda R, Tatehara S, Ide S, Umeki H, Miyoshi K, Noma T, Satomura K.
A New Induction Method for the Controlled Differentiation of Human-Induced Pluripotent Stem Cells Using Frozen Sections.
Cells
2021
10(11)
PubMed ID: 34831050
DOI: 10.3390/cells10112827
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6879
Kasai T, Suga H, Sakakibara M, Ozone C, Matsumoto R, Kano M, Mitsumoto K, Ogawa K, Kodani Y, Nagasaki H, Inoshita N, Sugiyama M, Onoue T, Tsunekawa T, Ito Y, Takagi H, Hagiwara D, Iwama S, Goto M, Banno R, Takahashi J, Arima H.
Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells.
Cell Rep
2020
30(1):18-24
PubMed ID: 31914385
DOI: 10.1016/j.celrep.2019.12.009
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10143
Tomoyo Sawada, Thomas E Chater, Yohei Sasagawa, Mika Yoshimura, Noriko Fujimori-Tonou, Kaori Tanaka, Kynon J M Benjamin, Apuã C M Paquola, Jennifer A Erwin, Yukiko Goda, Itoshi Nikaido, Tadafumi Kato
Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids
Mol Psychiatry
2020
25(11):2695-2711
PubMed ID: 32764691
DOI: 10.1038/s41380-020-0844-z
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11989
Dayem AA, Won J, Goo HG, Yang GM, Seo DS, Jeon BM, Choi HY, Park SE, Lim KM, Jang SH, Lee SB, Choi SB, Kim K, Kang GH, Yeon GB, Kim DS, Cho SG.
The immobilization of fibronectin- and fibroblast growth factor 2-derived peptides on a culture plate supports the attachment and proliferation of human pluripotent stem cells.
Stem Cell Res
2020
PubMed ID: 31981882
DOI: 10.1016/j.scr.2020.101700
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13010
Misawa R, Minami T, Okamoto A, Ikeuchi Y.
A Light-Inducible Hedgehog Signaling Activator Modulates Proliferation and Differentiation of Neural Cells.
ACS Chem Biol
2020
PubMed ID: 32343549
DOI: 10.1021/acschembio.0c00195
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13064
Maurissen TL, Woltjen K.
Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation.
Nat Commun
2020
PubMed ID: 32513994
DOI: 10.1038/s41467-020-16643-5
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13174
Yokouchi Y, Suzuki S, Ohtsuki N, Yamamoto K, Noguchi S, Soejima Y, Goto M, Ishioka K, Nakamura I, Suzuki S, Takenoshita S, Era T.
Rapid repair of human disease-specific single-nucleotide variants by One-SHOT genome editing.
Sci Rep
2020
PubMed ID: 32811847
DOI: 10.1038/s41598-020-70401-7
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13381
Sim H, Seo JH, Kim J, Oh M, Lee JE, Baek A, Lee SY, Chung SK, Son MY, Chae JI, Jeon YJ, Kim J.
Quantitative Proteomic Analysis of Primitive Neural Stem Cells from LRRK2 G2019S-Associated Parkinson's Disease Patient-Derived iPSCs.
Life (Basel)
2020
PubMed ID: 33297425
DOI: 10.3390/life10120331
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14062
Ayo-Martin AC, Kyrousi C, Di Giaimo R, Cappello S.
GNG5 Controls the Number of Apical and Basal Progenitors and Alters Neuronal Migration During Cortical Development
Front Mol Biosci
2020
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14943
Krieger TG, Tirier SM, Park J, Jechow K, Eisemann T, Peterziel H, Angel P, Eils R, Conrad C.
Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics
Neuro Oncol
2020
22(8):1138-1149
PubMed ID: 32297954
DOI: 10.1093/neuonc/noaa091
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16212
Kotaro Tsuboyama, Tatsuya Osaki, Eriko Matsuura-Suzuki, Hiroko Kozuka-Hata, Yuki Okada, Masaaki Oyama, Yoshiho Ikeuchi, Shintaro Iwasaki, Yukihide Tomari
A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation
PLoS Biol
2020
18(3):e3000632
PubMed ID: 32163402
DOI: 10.1371/journal.pbio.3000632
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16885
Osman A, Oze M, Afify SM, Hassan G, El-Ghlban S, Nawara HM, Fu X, Zahra MH, Seno A, Winer I, Salomon DS, Seno M.
Tumor-associated macrophages derived from cancer stem cells
Acta Histochem
2020
122(8):151628
PubMed ID: 32992123
DOI: 10.1016/j.acthis.2020.151628
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11304
Ueda M, Hashimoto Y, Honda Y, Baba S, Morita S.
Comparison of the characteristics of mesenchymal stem-like cells derived by integration-free induced pluripotent stem cells in different single-cell culture media under feeder-free conditions.
Med Mol Morphol
2019
PubMed ID: 30446810
DOI: 10.1007/s00795-018-0211-1
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4572
Kuroda T, Yasuda S, Tachi S, Matsuyama S, Kusakawa S, Tano K, Miura T, Matsuyama A, Sato Y.
SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation.
Nat Commun
2019
10(1):2175
PubMed ID: 31092818
DOI: 10.1038/s41467-019-09511-4
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5346
Kirihara T, Luo Z, Chow SYA, Misawa R, Kawada J, Shibata S, Khoyratee F, Vollette CA, Volz V, Levi T, Fujii T, Ikeuchi Y.
A Human Induced Pluripotent Stem Cell-Derived Tissue Model of a Cerebral Tract Connecting Two Cortical Regions.
iScience
2019
14:301-311
PubMed ID: 31006610
DOI: 10.1016/j.isci.2019.03.012
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11576
Komatsu Y, Takeuchi D, Tokunaga T, Sakurai H, Makino A, Honda T, Ikeda Y, Tomonaga K.
RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs.
Mol Ther Methods Clin Dev
2019
14:47-55
PubMed ID: 31309127
DOI: 10.1016/j.omtm.2019.05.010
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11589
Aoki H, Yamashita M, Hashita T, Nakayama M, Yagi M, Iwao T, Matsunaga T.
Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.
Biochem. Biophys. Res. Commun.
2019
515(4):672-678
PubMed ID: 31178142
DOI: 10.1016/j.bbrc.2019.05.179
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11744
Riesenberg S, Chintalapati M, Macak D, Kanis P, Maricic T, Pääbo S.
Simultaneous precise editing of multiple genes in human cells.
Nucleic Acids Res.
2019
PubMed ID: 31392986
DOI: 10.1093/nar/gkz669
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11860
Kanton S, Boyle MJ, He Z, Santel M, Weigert A, Sanchís-Calleja F, Guijarro P, Sidow L, Fleck JS, Han D, Qian Z, Heide M, Huttner WB, Khaitovich P, Pääbo S, Treutlein B, Camp JG.
Organoid single-cell genomic atlas uncovers human-specific features of brain development.
Nature
2019
PubMed ID: 31619793
DOI: 10.1038/s41586-019-1654-9
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10578
Yuki Maeda, Keiichi Motoyama, Taishi Higashi, Risako Onodera, Toru Takeo, Naomi Nakagata, Yuki Kurauchi, Hiroshi Katsuki, Yoichi Ishitsuka, Yuki Kondo, Tetsumi Irie, Takumi Era, Hidetoshi Arima
Lowering effect of dimethyl-α-cyclodextrin on GM1-ganglioside accumulation in GM1-gangliosidosis model cells and in brain of β-galactosidase-knockout mice
Journal of Inclusion Phenomena and Macrocyclic Chemistry
2019
93:53–66
DOI: 10.1007/s10847-018-0835-8
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12368
Kimura Y, Shofuda T, Higuchi Y, Nagamori I, Oda M, Nakamori M, Onodera M, Kanematsu D, Yamamoto A, Katsuma A, Suemizu H, Nakano T, Kanemura Y, Mochizuki H.
Human Genomic Safe Harbors and the Suicide Gene-Based Safeguard System for iPSC-Based Cell Therapy
Stem Cells Transl Med
2019
8(7):627-638
PubMed ID: 30887735
DOI: 10.1002/sctm.18-0039
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Akiyama T, Sato S, Chikazawa-Nohtomi N, Soma A, Kimura H, Wakabayashi S, Ko SBH, Ko MSH.
Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing.
Sci Rep
2018
8:1189
PubMed ID: 29352121
DOI: 10.1038/s41598-017-19114-y
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Sato-Nishiuchi R, Li S, Ebisu F, Sekiguchi K.
Recombinant laminin fragments endowed with collagen-binding activity: A tool for conferring laminin-like cell-adhesive activity to collagen matrices.
Matrix Biol.
2018
65:75-90
PubMed ID: 28801205
DOI: 10.1016/j.matbio.2017.08.001
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Yasuda S, Kusakawa S, Kuroda T, Miura T, Tano K, Takada N, Matsuyama S, Matsuyama A, Nasu M, Umezawa A, Hayakawa T, Tsutsumi H, Sato Y.
Tumorigenicity-associated characteristics of human iPS cell lines.
PLoS ONE
2018
PubMed ID: 30286143
DOI: 10.1371/journal.pone.0205022
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4124
Ikeda K, Kawasaki Y, Matsuda H, Kishida S, Iwasaki A, Ohata S, Urashima Y, Hirotani Y.
Approach for differentiating trophoblast cell lineage from human induced pluripotent stem cells with retinoic acid in the absence of bone morphogenetic protein 4.
Placenta
2018
PubMed ID: 30415744
DOI: 10.1016/j.placenta.2018.10.001
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5348
Yoshinori Hasegawa, Masashi Ikeno, Nobutaka Suzuki, Manabu Nakayama, Osamu Ohara
Improving the efficiency of gene insertion in a human artificial chromosome vector and its transfer in human-induced pluripotent stem cells
Biology Methods and Protocols
2018
1–10
PubMed ID: 32161806
DOI: 10.1093/biomethods/bpy013
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Yokoi T, Tanaka T, Matsuzaka E, Tamalu F, Watanabe SI, Nishina S, Azuma N.
Effects of neuroactive agents on axonal growth and pathfinding of retinal ganglion cells generated from human stem cells.
Sci Rep
2017
7:16757
PubMed ID: 29196712
DOI: 10.1038/s41598-017-16727-1
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7015
Kawada J, Kaneda S, Kirihara T, Maroof A, Levi T, Eggan K, Fujii T, Ikeuchi Y.
Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons.
Stem Cell Reports
2017
9:1441-1449
PubMed ID: 29107592
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7026
Koui Y, Kido T, Ito T, Oyama H, Chen SW, Katou Y, Shirahige K, Miyajima A.
An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells.
Stem Cell Reports
2017
9:490-498
PubMed ID: 28757162
DOI: 10.1016/j.stemcr.2017.06.010
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7031
Ikeda K, Nagata S, Okitsu T, Takeuchi S.
Cell fiber-based three-dimensional culture system for highly efficient expansion of human induced pluripotent stem cells.
Sci Rep
2017
7:2850
PubMed ID: 28588295
DOI: 10.1038/s41598-017-03246-2
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9918
Shimizu Y, Satou M, Hayashi K, Nakamura Y, Fujimaki M, Horibata Y, Ando H, Watanabe T, Shiobara T, Chibana K, Takemasa A, Sugimoto H, Anzai N, Ishii Y.
Matrix-assisted laser desorption/ionization imaging mass spectrometry reveals changes of phospholipid distribution in induced pluripotent stem cell colony differentiation.
Anal Bioanal Chem
2017
409:1007-1016
PubMed ID: 27815610
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Zuiki M, Chiyonobu T, Yoshida M, Maeda H, Yamashita S, Kidowaki S, Hasegawa T, Gotoh H, Nomura T, Ono K, Hosoi H, Morimoto M.
Luteolin attenuates interleukin-6-mediated astrogliosis in human iPSC-derived neural aggregates: A candidate preventive substance for maternal immune activation-induced abnormalities.
Neurosci. Lett.
2017
653:296-301
PubMed ID: 28595950
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Bamba Y, Kanemura Y, Okano H, Yamasaki M.
Visualization of migration of human cortical neurons generated from induced pluripotent stem cells.
J. Neurosci. Methods
2017
289:57-63
PubMed ID: 28694214
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5774
Miyagoe-Suzuki Y, Nishiyama T, Nakamura M, Narita A, Takemura F, Masuda S, Minami N, Murayama K, Komaki H, Goto YI, Takeda S.
Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status.
Stem Cells Int
2017
2017:7906843
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6234
Nakamura Y, Shimizu Y, Horibata Y, Tei R, Koike R, Masawa M, Watanabe T, Shiobara T, Arai R, Chibana K, Takemasa A, Sugimoto H, Ishii Y.
Changes of plasmalogen phospholipid levels during differentiation of induced pluripotent stem cells 409B2 to endothelial phenotype cells.
Sci Rep
2017
7(1):9377
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Maeda T, Nagano S, Ichise H, Kataoka K, Yamada D, Ogawa S, Koseki H, Kitawaki T, Kadowaki N, Takaori-Kondo A, Masuda K, Kawamoto H.
Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity.
Cancer Res.
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76:6839-6850
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Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development.
Elife
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Kido T, Koui Y, Suzuki K, Kobayashi A, Miura Y, Chern EY, Tanaka M, Miyajima A.
CPM Is a Useful Cell Surface Marker to Isolate Expandable Bi-Potential Liver Progenitor Cells Derived from Human iPS Cells.
Stem Cell Reports
2015
5:508-15
PubMed ID: 26365514
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5451
Tanaka T, Yokoi T, Tamalu F, Watanabe S, Nishina S, Azuma N.
Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells.
Sci Rep
2015
5:8344
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Baden MY, Fukui K, Hosokawa Y, Iwahashi H, Imagawa A, Shimomura I.
Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue.
PLoS One
2015
10(12):e0144606
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Sasaki H, Wada H, Baghdadi M, Tsuji H, Otsuka R, Morita K, Shinohara N, Seino K.
New Immunosuppressive Cell Therapy to Prolong Survival of Induced Pluripotent Stem Cell-Derived Allografts
Transplantation
2015
99(11):2301-10
PubMed ID: 26360665
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5741
Tano K, Yasuda S, Kuroda T, Saito H, Umezawa A, Sato Y.
A novel in vitro method for detecting undifferentiated human pluripotent stem cells as impurities in cell therapy products using a highly efficient culture system.
PLoS One
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9(10):e110496
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Chemoreflex sensitization augments sympathetic vasomotor outflow in awake humans.
Adv. Exp. Med. Biol.
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