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Cell No. : Cell Name
RCB5341 : RAD54-TK6  update : 2022/09/06
CommentCurrently not ready.
Comment from the depositorTK6 cells are one of the most commonly used human B lymphocyte-derived cell for cancer research. RAD54- disrupted TK6 cells.
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Expected time Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
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Reference
17836  Wikiniyadhanee R, Lerksuthirat T, Stitchantrakul W, Chitphuk S, Takeda S, Dejsuphong D.  ATR Inhibitor Synergizes PARP Inhibitor Cytotoxicity in Homologous Recombination Repair Deficiency TK6 Cell Lines  Biomed Res Int  2023  2023:7891753  PubMed ID: 36794257   DOI: 10.1155/2023/7891753
17859  Zhao Z, Wu X, He F, Xiang C, Feng X, Bai X, Liu X, Zhao J, Takeda S, Qing Y.  Critical roles of Rad54 in tolerance to apigenin-induced Top1-mediated DNA damage  Exp Ther Med  2021  21(5):505  PubMed ID: 33791014   DOI: 10.3892/etm.2021.9936
17844  Rahman MM, Mohiuddin M, Shamima Keka I, Yamada K, Tsuda M, Sasanuma H, Andreani J, Guerois R, Borde V, Charbonnier JB, Takeda S.  Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination  J Biol Chem  2020  17460-17475  PubMed ID: 33453991   DOI: 10.1074/jbc.RA120.013521
17862  Naoto Shimizu, Remi Akagawa, Shunichi Takeda, Hiroyuki Sasanuma  The MRE11 nuclease promotes homologous recombination not only in DNA double-strand break resection but also in post-resection in human TK6 cells  Genome Instability & Disease  2020  1:184-196    DOI: 10.1007/s42764-020-00015-w
17840  Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S.  PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching  PLoS One  2019  14(3):e0213383  PubMed ID: 30840704   DOI: 10.1371/journal.pone.0213383
17839  Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.  Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes  Mol Cell  2016  64(3):580-592  PubMed ID: 27814490   DOI: 10.1016/j.molcel.2016.10.011
17830  Hoa NN, Akagawa R, Yamasaki T, Hirota K, Sasa K, Natsume T, Kobayashi J, Sakuma T, Yamamoto T, Komatsu K, Kanemaki MT, Pommier Y, Takeda S, Sasanuma H.  Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines  Genes Cells  2015  20(12):1059-76  PubMed ID: 26525166   DOI: 10.1111/gtc.12310
17842  Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H.  Smarcal1 promotes double-strand-break repair by nonhomologous end-joining  Nucleic Acids Res  2015  43(13):6359-72  PubMed ID: 26089390   DOI: 10.1093/nar/gkv621
279  Skopek TR, Liber HL, Penman BW, Thilly WG.  Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay  Biochem Biophys Res Commun  1978  84(2):411-6  PubMed ID: 214074   DOI: 10.1016/0006-291x(78)90185-7
281  Levy JA, Buell DN, Creech C, Hirshaut Y, Silverberg H.  Further characterization of the WI-L1 and WI-L2 lymphoblastoid lines  J Natl Cancer Inst  1971  46(3):647-54  PubMed ID: 4323138  
280  Levy JA, Virolainen M, Defendi V.  Human lymphoblastoid lines from lymph node and spleen  Cancer  1968  22(3):517-24  PubMed ID: 5673231   DOI: 10.1002/1097-0142(196809)22:3<517::aid-cncr2820220305>3.0.co;2-a

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