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Cell No. : Cell Name
RCB5324 : LIG4-TK6  update : 2022/09/06
CommentCurrently not ready.
Comment from the depositorTK6 cells are one of the most commonly used human B lymphocyte-derived cell for cancer research. LIG4- disrupted TK6 cells.
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Expected time Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
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Reference
17857  Akagawa R, Trinh HT, Saha LK, Tsuda M, Hirota K, Yamada S, Shibata A, Kanemaki MT, Nakada S, Takeda S, Sasanuma H.  UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks  iScience  2020  23(4):101027  PubMed ID: 32283528   DOI: 10.1016/j.isci.2020.101027
17839  Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.  Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes  Mol Cell  2016  64(3):580-592  PubMed ID: 27814490   DOI: 10.1016/j.molcel.2016.10.011
17842  Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H.  Smarcal1 promotes double-strand-break repair by nonhomologous end-joining  Nucleic Acids Res  2015  43(13):6359-72  PubMed ID: 26089390   DOI: 10.1093/nar/gkv621
279  Skopek TR, Liber HL, Penman BW, Thilly WG.  Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay  Biochem Biophys Res Commun  1978  84(2):411-6  PubMed ID: 214074   DOI: 10.1016/0006-291x(78)90185-7
281  Levy JA, Buell DN, Creech C, Hirshaut Y, Silverberg H.  Further characterization of the WI-L1 and WI-L2 lymphoblastoid lines  J Natl Cancer Inst  1971  46(3):647-54  PubMed ID: 4323138  
280  Levy JA, Virolainen M, Defendi V.  Human lymphoblastoid lines from lymph node and spleen  Cancer  1968  22(3):517-24  PubMed ID: 5673231   DOI: 10.1002/1097-0142(196809)22:3<517::aid-cncr2820220305>3.0.co;2-a

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