細胞番号 : 細胞名 RCB3532 : A129L  update : 2023/10/16
細胞特性(Comment:英)			Human cell line derived from lung adenocarcinoma cells.
細胞特性(日)			ヒト肺腺癌由来細胞株。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)			In publishing research results obtained by the use of the BIOLOGICAL RESOURCE, a citation of the literature ref. (Chest 2002;122:282-288.) designated by the DEPOSITOR is required.
使用条件(日)			利用者は、研究成果の公表にあたって寄託者の指定する文献 (Chest 2002;122:282-288) を引用すること。
備考(英)
備考(日)
提供申込書類(英)			Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)
			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日)			依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf
			提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料			手数料とお支払いについてはこちらをご覧ください。
細胞基本情報		寄託者	Hanagiri, Takeshi
		樹立者	Takenoyama, Mitsuhiro
		寄託日	2010
		動物種	_human < Mammals
		属名	Homo
		種名	sapiens
		人種	Japanese
		性別	Male
		齢	64 years
		採取組織	lung
		病名	adenocarcinoma
		細胞分類	cancer
		初代培養日	1996
		細胞寿命	infinite
		細胞形態	epithelial-like
		Cellosaurus(Expasy)	CVCL_U094
細胞培養・検査情報			寄託時情報	ロット情報
	培地・試薬情報		培地・試薬一覧はこちらをご覧ください。
		培養形態		Adherent cells
		培地		RPMI1640 + 10mM HEPES + 10% FBS
		抗生物質		Free
		継代方法		0.25% Trypsin
		継代密度		1 : 4-6 split
		継代・培地交換頻度		Subculture : once/week, Medium Renewal : 2 times/week
		培養最適温度		37 ℃
		二酸化炭素濃度		5 %
		凍結培地		Medium + 10% DMSO
		凍結方法		Slow freezing
		マイコプラズマ		(-)
		動物種PCR		OK
		個体識別検査		OK
画像情報			寄託時情報	ロット情報
文献情報		Reference(英)	11件
		Reference(日)	0件
		利用者成果(英)	1件
		利用者成果(日)	0件

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Reference(英)

8991  Manabu Yasuda, Takeshi Hanagiri, Yoshiki Shigematsu, Takamitsu Onitsuka, Kouji Kuroda, Tetsurou Baba, Makiko Mizukami, Yoshinobu Ichiki, Hidetaka Uramoto, Mitsuhiro Takenoyama, Kosei Yasumoto  Identification of a Tumour Associated Antigen in Lung Cancer Patients With Asbestos Exposure  Anticancer Res  2010  30 (7), 2631-9  PubMed ID: 20682992

8990  Kosei Yasumoto, Takeshi Hanagiri, Mitsuhiro Takenoyama  Lung Cancer-Associated Tumor Antigens and the Present Status of Immunotherapy Against Non-Small-Cell Lung Cancer  Gen Thorac Cardiovasc Surg  2009  57 (9), 449-57  PubMed ID: 19756930   DOI: 10.1007/s11748-008-0433-6

3628  Baba T, Hanagiri T, Ichiki Y, Kuroda K, Shigematsu Y, Mizukami M, Sugaya M, Takenoyama M, Sugio K, Yasumoto K.  Lack and restoration of sensitivity of lung cancer cells to cellular attack with special reference to expression of human leukocyte antigen class I and/or major histocompatibility complex class I chain related molecules A/B.  Cancer Sci  2007  98(11):1795-802  PubMed ID: 17725806   DOI: 10.1111/j.1349-7006.2007.00586.x

3637  Sugaya M, Takenoyama M, Shigematsu Y, Baba T, Fukuyama T, Nagata Y, Mizukami M, So T, Ichiki Y, Yasuda M, So T, Hanagiri T, Sugio K, Yasumoto K.  Identification of HLA-A24 restricted shared antigen recognized by autologous cytotoxic T lymphocytes from a patient with large cell carcinoma of the lung.  Int J Cancer  2007  120(5):1055-62  PubMed ID: 17131342   DOI: 10.1002/ijc.22396

8995  Takashi Fukuyama, Yoshinobu Ichiki, Sousuke Yamada, Yoshiki Shigematsu, Tetsuro Baba, Yoshika Nagata, Makiko Mizukami, Masakazu Sugaya, Mitsuhiro Takenoyama, Takeshi Hanagiri, Kenji Sugio, Kosei Yasumoto  Cytokine Production of Lung Cancer Cell Lines: Correlation Between Their Production and the Inflammatory/Immunological Responses Both in Vivo and in Vitro  Cancer Sci  2007  98 (7), 1048-54  PubMed ID: 17511773   DOI: 10.1111/j.1349-7006.2007.00507.x

9004  Makiko Mizukami, Takeshi Hanagiri, Manabu Yasuda, Koji Kuroda, Yoshiki Shigematsu, Tetsuro Baba, Takashi Fukuyama, Yoshika Nagata, Tetsuya So, Yoshinobu Ichiki, Masakazu Sugaya, Tomoko So, Mitsuhiro Takenoyama, Kenji Sugio, Kosei Yasumoto  Antitumor Effect of Antibody Against a SEREX-defined Antigen (UOEH-LC-1) on Lung Cancer Xenotransplanted Into Severe Combined Immunodeficiency Mice  Cancer Res  2007  67 (17), 8351-7  PubMed ID: 17804751   DOI: 10.1158/0008-5472.CAN-06-3889

8988  Takashi Fukuyama, Takeshi Hanagiri, Mitsuhiro Takenoyama, Yoshinobu Ichiki, Makiko Mizukami, Tetsuya So, Masakazu Sugaya, Tomoko So, Kenji Sugio, Kosei Yasumoto  Identification of a New Cancer/Germline Gene, KK-LC-1, Encoding an Antigen Recognized by Autologous CTL Induced on Human Lung Adenocarcinoma  Cancer Res  2006  66 (9), 4922-8  PubMed ID: 16651449   DOI: 10.1158/0008-5472.CAN-05-3840

7413  Mizukami M, Hanagiri T, Baba T, Fukuyama T, Nagata Y, So T, Ichiki Y, Sugaya M, Yasuda M, Takenoyama M, Sugio K, Yasumoto K.  Identification of tumor associated antigens recognized by IgG from tumor-infiltrating B cells of lung cancer: correlation between Ab titer of the patient's sera and the clinical course.  Cancer Sci  2005  96(12):882-8  PubMed ID: 16367908   DOI: 10.1111/j.1349-7006.2005.00119.x

8998  Yoshinobu Ichiki, Takeshi Hanagiri, Mitsuhiro Takenoyama, Tetsuro Baba, Takashi Fukuyama, Yoshika Nagata, Makiko Mizukami, Tetsuya So, Masakazu Sugaya, Manabu Yasuda, Tomoko So, Kenji Sugio, Kosei Yasumoto  Tumor Specific Expression of survivin-2B in Lung Cancer as a Novel Target of Immunotherapy  Lung Cancer  2005  48 (2), 281-9  PubMed ID: 15829330   DOI: 10.1016/j.lungcan.2004.10.017

3638  Sugaya M, Takenoyama M, Osaki T, Yasuda M, Nagashima A, Sugio K, Yasumoto K.  Establishment of 15 cancer cell lines from patients with lung cancer and the potential tools for immunotherapy.  Chest  2002  122(1):282-8  PubMed ID: 12114371   DOI: 10.1378/chest.122.1.282

8994  R Eifuku, M Takenoyama, I Yoshino, S Imahayashi, T So, M Yasuda, M Sugaya, K Yasumoto  Analysis of MAGE-3 Derived Synthetic Peptide as a Human Lung Cancer Antigen Recognized by Cytotoxic T Lymphocytes  Int J Clin Oncol  2001  6 (1), 34-9  PubMed ID: 11706525   DOI: 10.1007/pl00012077

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Reference(日)

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利用者成果(英)

9006  Lilong Xia, Xinhai Zhu 1, Lei Zhang 1, Yanhui Xu 1, Guoping Chen 1, Jing Luo 1  EZH2 Enhances Expression of CCL5 to Promote Recruitment of Macrophages and Invasion in Lung Cancer  Biotechnol Appl Biochem  2020  67(6):1011-1019  PubMed ID: 31855281   DOI: 10.1002/bab.1875

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利用者成果(日)