利用者成果(英) |
22050
Annagrazia Adornetto, Maria Luisa Laganà, Andrea Satriano, Ester Licastro, Maria Tiziana Corasaniti, Giacinto Bagetta, Rossella Russo
The Antidepressant Drug Amitriptyline Affects Human SH-SY5Y Neuroblastoma Cell Proliferation and Modulates Autophagy
International Journal of Molecular Sciences
2924
25:10415
DOI: 10.3390/ijms251910415
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17739
Hung CH, Yen JB, Chang PJ, Chen LW, Huang TY, Tsai WJ, Tsai YC.
Characterization of Human Norovirus Nonstructural Protein NS1.2 Involved in the Induction of the Filamentous Endoplasmic Reticulum, Enlarged Lipid Droplets, LC3 Recruitment, and Interaction with NTPase and NS4
Viruses
2023
15(3):812
PubMed ID: 36992520
DOI: 10.3390/v15030812
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19944
Aihara S, Torisu K, Uchida Y, Imazu N, Nakano T, Kitazono T.
Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis
Commun Biol
2023
6(1):676
PubMed ID: 37380734
DOI: 10.1038/s42003-023-05057-w
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16429
Kim EY, Lee JM.
Basal Autophagy Is Necessary for A Pharmacologic PPARα Transactivation
Cells
2022
11(4):754
PubMed ID: 35203398
DOI: 10.3390/cells11040754
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20691
Kajiwara K, Osaki H, Greßies S, Kuwata K, Kim JH, Gensch T, Sato Y, Glorius F, Yamaguchi S, Taki M.
A negative-solvatochromic fluorescent probe for visualizing intracellular distributions of fatty acid metabolites.
Nat Commun
2022
13(1):2533
PubMed ID: 35534485
DOI: 10.1038/s41467-022-30153-6
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18096
Qiao Y, Choi JE, Tien JC, Simko SA, Rajendiran T, Vo JN, Delekta AD, Wang L, Xiao L, Hodge NB, Desai P, Mendoza S, Juckette K, Xu A, Soni T, Su F, Wang R, Cao X, Yu J, Kryczek I, Wang XM, Wang X, Siddiqui J, Wang Z, Bernard A, Fernandez-Salas E, Navone NM, Ellison SJ, Ding K, Eskelinen EL, Heath EI, Klionsky DJ, Zou W, Chinnaiyan AM.
Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer
Nat Cancer
2021
2:978-993
PubMed ID: 34738088
DOI: 10.1038/s43018-021-00237-1
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16432
Sarkar R, Sharma KB, Kumari A, Asthana S, Kalia M.
Japanese encephalitis virus capsid protein interacts with non-lipidated MAP1LC3 on replication membranes and lipid droplets
J Gen Virol
2021
Jan;102(1)
PubMed ID: 33095129
DOI: 10.1099/jgv.0.001508
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16981
Uchida Y, Torisu K, Ueki K, Tsuruya K, Nakano T, Kitazono T.
Autophagy gene ATG7 regulates albumin transcytosis in renal tubule epithelial cells
Am J Physiol Renal Physiol
2021
321(5):F572-F586
PubMed ID: 34541900
DOI: 10.1152/ajprenal.00172.2021
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11865
Xu ZD, Wang Y, Liang G, Liu ZQ, Ma WH, Chu CT, Wei HF.
Propofol affects mouse embryonic fibroblast survival and proliferation in vitro via ATG5- and calcium-dependent regulation of autophagy.
Acta Pharmacol. Sin.
2020
41(3):303-310
PubMed ID: 31645660
DOI: 10.1038/s41401-019-0303-z
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11959
Muscolino E, Schmitz R, Loroch S, Caragliano E, Schneider C, Rizzato M, Kim YH, Krause E, Juranić Lisnić V, Sickmann A, Reimer R, Ostermann E, Brune W.
Herpesviruses induce aggregation and selective autophagy of host signalling proteins NEMO and RIPK1 as an immune-evasion mechanism.
Nat Microbiol
2020
PubMed ID: 31844296
DOI: 10.1038/s41564-019-0624-1
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13223
Liu EA, Schultz ML, Mochida C, Chung C, Paulson HL, Lieberman AP.
Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain.
JCI Insight
2020
PubMed ID: 32931479
DOI: 10.1172/jci.insight.136676
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15153
Hitomi K, Okada R, Loo TM, Miyata K, Nakamura AJ, Takahashi A.
DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses
Int J Mol Sci
2020
21(10):3720
PubMed ID: 32466233
DOI: 10.3390/ijms21103720
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11371
Aki T, Unuma K, Noritake K, Hirayama N, Funakoshi T, Uemura K.
Formation of high molecular weight p62 by CORM-3.
PLoS ONE
2019
PubMed ID: 30620762
DOI: 10.1371/journal.pone.0210474
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11463
Iwasawa T, Shinomiya T, Ota N, Shibata N, Nakata K, Shiina I, Nagahara Y.
Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.
Biol. Pharm. Bull.
2019
PubMed ID: 30828072
DOI: 10.1248/bpb.b18-00643
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5357
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
2019
76(5):797-810
PubMed ID: 31606272
DOI: 10.1016/j.molcel.2019.09.009
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11727
Ji CH, Kim HY, Heo AJ, Lee SH, Lee MJ, Kim SB, Srinivasrao G, Mun SR, Cha-Molstad H, Ciechanover A, Choi CY, Lee HG, Kim BY, Kwon YT.
The N-Degron Pathway Mediates ER-phagy.
Mol. Cell
2019
PubMed ID: 31375263
DOI: 10.1016/j.molcel.2019.06.028
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6908
Ko PJ, Woodrow C, Dubreuil MM, Martin BR, Skouta R, Bassik MC, Dixon S.
A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death.
Cell Chem Biol
2019
26(12):1716-1724
PubMed ID: 31631010
DOI: 10.1016/j.chembiol.2019.09.014
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9135
Kiran Bala Sharma, Manish Sharma, Suruchi Aggarwal, Amit Kumar Yadav, Shinjini Bhatnagar, Sudhanshu Vrati, Manjula Kalia
Quantitative Proteome Analysis of Atg5-Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome
mSystems
2019
4 (6) 2019
PubMed ID: 31690592
DOI: 10.1128/mSystems.00481-19
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9181
Huiyin Lan, Mingjia Tan, Qiang Zhang, Fei Yang, Siyuan Wang, Hua Li, Xiufang Xiong, Yi Sun
LSD1 Destabilizes FBXW7 and Abrogates FBXW7 Functions Independent of Its Demethylase Activity
Proc Natl Acad Sci U S A
2019
116 (25), 12311-12320
PubMed ID: 31152129
DOI: 10.1073/pnas.1902012116
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4148
Aki T, Unuma K, Noritake K, Kurahashi H, Funakoshi T, Uemura K.
Interaction of carbon monoxide-releasing ruthenium carbonyl CORM-3 with plasma fibronectin.
Toxicol In Vitro
2018
PubMed ID: 29580987
DOI: 10.1016/j.tiv.2018.03.010
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9173
Alexa R Wilden, Joshua A Molina, Melissa Feuerborn, Daniel Boyle, Stella Y Lee
Glutamine-dependent Lysosome Homeostatic Changes Induced by Starvation and Lysosome Inhibition
Biochim Biophys Acta Mol Cell Res
2018
1865 (9), 1356-1367
PubMed ID: 29966622
DOI: 10.1016/j.bbamcr.2018.06.014
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9180
Sang Mi Shim 1 2, Ha Rim Choi, Ki Woon Sung, Yoon Jee Lee, Sung Tae Kim , Daeho Kim, Su Ran Mun, Joonsung Hwang, Hyunjoo Cha-Molstad, Aaron Ciechanover, Bo Yeon Kim, Yong Tae Kwon
The Endoplasmic Reticulum-Residing Chaperone BiP Is Short-Lived and Metabolized Through N-terminal Arginylation
Sci Signal
2018
11 (511)
PubMed ID: 29295953
DOI: 10.1126/scisignal.aan0630
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15047
Real E, Rodrigues L, Cabal GG, Enguita FJ, Mancio-Silva L, Mello-Vieira J, Beatty W, Vera IM, Zuzarte-Luís V, Figueira TN, Mair GR, Mota MM.
Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes
Nat Microbiol
2018
3(1):17-25
PubMed ID: 29109477
DOI: 10.1038/s41564-017-0054-x
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9185
Hyunjoo Cha-Molstad, Ji Eun Yu, Zhiwei Feng, Su Hyun Lee, Jung Gi Kim, Peng Yang, Bitnara Han, Ki Woon Sung, Young Dong Yoo, Joonsung Hwang, Terry McGuire, Sang Mi Shim, Hyun Dong Song, Srinivasrao Ganipisetti 1, Nuozhou Wang, Jun Min Jang, Min Jae Lee, Seung Jun Kim, Kyung Ho Lee 1, Jin Tae Hong, Aaron Ciechanover , Inhee Mook-Jung, Kwang Pyo Kim, Xiang-Qun Xie, Yong Tae Kwon, Bo Yeon Kim
p62/SQSTM1/Sequestosome-1 Is an N-recognin of the N-end Rule Pathway Which Modulates Autophagosome Biogenesis
Nat Commun
2017
8 (1), 102
PubMed ID: 28740232
DOI: 10.1038/s41467-017-00085-7
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14213
Into T, Horie T, Inomata M, Gohda J, Inoue JI, Murakami Y, Niida S.
Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
Sci Rep
2017
7(1):1009
PubMed ID: 28432355
DOI: 10.1038/s41598-017-01246-w
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14756
Kawano S, Torisu T, Esaki M, Torisu K, Matsuno Y, Kitazono T.
Autophagy promotes degradation of internalized collagen and regulates distribution of focal adhesions to suppress cell adhesion
Biol Open
2017
6(11):1644-1653
PubMed ID: 28970230
DOI: 10.1242/bio.027458
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9158
Nguyen T Tien, Ilker Karaca , Irfan Y Tamboli, Jochen Walter
Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein
J Biol Chem
2016
291 (20), 10528-40
PubMed ID: 26957541
DOI: 10.1074/jbc.M116.719286
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14144
Kumari B, Jain P, Das S, Ghosal S, Hazra B, Trivedi AC, Basu A, Chakrabarti J, Vrati S, Banerjee A.
Dynamic changes in global microRNAome and transcriptome reveal complex miRNA-mRNA regulated host response to Japanese Encephalitis Virus in microglial cells
Sci Rep
2016
6:20263
PubMed ID: 26838068
DOI: 10.1038/srep20263
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9136
Yuko Hirota, Shun-ichi Yamashita, Yusuke Kurihara, Xiulian Jin, Masamune Aihara, Tetsu Saigusa, Dongchon Kang, Tomotake Kanki
Mitophagy Is Primarily Due to Alternative Autophagy and Requires the MAPK1 and MAPK14 Signaling Pathways
Autophagy
2015
11 (2), 332-43
PubMed ID: 25831013
DOI: 10.1080/15548627.2015.1023047
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9164
Bhavya B Chandrika, Cheng Yang, Yang Ou, Xiaoke Feng, Djamali Muhoza, Alexandrea F Holmes, Sue Theus, Sarika Deshmukh, Randy S Haun, Gur P Kaushal
Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection From Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury
PLoS One
2015
10 (10), e0140025
PubMed ID: 26444017
DOI: 10.1371/journal.pone.0140025
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9182
Takahiro Higuchi, Jun Nishikawa, Hiroko Inoue
Sucrose Induces Vesicle Accumulation and Autophagy
J Cell Biochem
2015
116 (4), 609-17
PubMed ID: 25389129
DOI: 10.1002/jcb.25012
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15041
Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT.
Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding
Nat Cell Biol
2015
17(7):917-29
PubMed ID: 26075355
DOI: 10.1038/ncb3177
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15211
Unuma K, Aki T, Funakoshi T, Hashimoto K, Uemura K.
Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy
Autophagy
2015
11(9):1520-36
PubMed ID: 26102061
DOI: 10.1080/15548627.2015.1063765
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9111
Shintaro Kobayashi, Yasuko Orba, Hiroki Yamaguchi, Kenta Takahashi, Michihito Sasaki, Rie Hasebe, Takashi Kimura, Hirofumi Sawa
Autophagy Inhibits Viral Genome Replication and Gene Expression Stages in West Nile Virus Infection
Virus Res
2014
191, 83-91
PubMed ID: 25091564
DOI: 10.1016/j.virusres.2014.07.016
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9137
Isabelle Hamer, Emeline Goffin, Xavier De Bolle, Jean-Jacques Letesson, Michel Jadot
Replication of Brucella Abortus and Brucella Melitensis in Fibroblasts Does Not Require Atg5-dependent Macroautophagy
BMC Microbiol
2014
14, 223
PubMed ID: 25179110
DOI: 10.1186/s12866-014-0223-5
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9184
Bo-Jhih Guan, Dawid Krokowski, Mithu Majumder, Christine L Schmotzer, Scot R Kimball, William C Merrick, Antonis E Koromilas, Maria Hatzoglou
Translational Control During Endoplasmic Reticulum Stress Beyond Phosphorylation of the Translation Initiation Factor eIF2α
J Biol Chem
2014
289 (18), 12593-611
PubMed ID: 24648524
DOI: 10.1074/jbc.M113.543215
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15871
McLelland GL, Soubannier V, Chen CX, McBride HM, Fon EA.
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
EMBO J
2014
33(4):282-95
PubMed ID: 24446486
DOI: 10.1002/embj.201385902
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16009
Sharma M, Bhattacharyya S, Nain M, Kaur M, Sood V, Gupta V, Khasa R, Abdin MZ, Vrati S, Kalia M.
Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes
Autophagy
2014
10(9):1637-51
PubMed ID: 25046112
DOI: 10.4161/auto.29455
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9151
Emi Sato, Shinichi Imafuku, Kazunari Ishii, Ryota Itoh, Bin Chou, Toshinori Soejima, Juichiro Nakayama, Kenji Hiromatsu
Vitamin D-dependent Cathelicidin Inhibits Mycobacterium Marinum Infection in Human Monocytic Cells
J Dermatol Sci
2013
70 (3), 166-72
PubMed ID: 23452544
DOI: 10.1016/j.jdermsci.2013.01.011
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9165
Hiroko Inoue, Katsunori Hase, Arata Segawa, Tsuyoshi Takita
H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulphonamide) Induces Autophagy Independently of Protein Kinase A Inhibition
Eur J Pharmacol
2013
714 (1-3), 170-7
PubMed ID: 23810683
DOI: 10.1016/j.ejphar.2013.06.018
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9168
Shintaro Kobayashi, Tadaki Suzuki, Manabu Igarashi, Yasuko Orba, Noriko Ohtake, Keita Nagakawa, Kenichi Niikura, Takashi Kimura, Harumi Kasamatsu, Hirofumi Sawa
Cysteine Residues in the Major Capsid Protein, Vp1, of the JC Virus Are Important for Protein Stability and Oligomer Formation
PLoS One
2013
8 (10), e76668
PubMed ID: 24130786
DOI: 10.1371/journal.pone.0076668
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9150
Yutaka Ueda, Fan-Yan Wei, Taku-ichiro Hide, Hiroyuki Michiue, Kentaro Takayama, Taku Kaitsuka, Hideo Nakamura, Keishi Makino, Jun-ichi Kuratsu, Shiroh Futaki, Kazuhito Tomizawa
Induction of Autophagic Cell Death of Glioma-Initiating Cells by Cell-Penetrating D-isomer Peptides Consisting of Pas and the p53 C-terminus
Biomaterials
2012
33 (35), 9061-9
PubMed ID: 23006589
DOI: 10.1016/j.biomaterials.2012.09.003
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9153
Satoshi Tsuyuki, Sayuri Fukui, Akari Watanabe, Satoshi Akune, Mizuki Tanabe, Kenichi Yoshida
Delphinidin Induces Autolysosome as Well as Autophagosome Formation and Delphinidin-Induced Autophagy Exerts a Cell Protective Role
J Biochem Mol Toxicol
2012
26 (11), 445-53
PubMed ID: 23129091
DOI: 10.1002/jbt.21443
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9154
Kai Er Eng, Marc D Panas, Deirdre Murphy, Gunilla B Karlsson Hedestam, Gerald M McInerney
Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins
J Virol
2012
86 (10), 5674-85
PubMed ID: 22438538
DOI: 10.1128/JVI.06581-11
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7903
Tian Y, Bustos V, Flajolet M, Greengard P.
A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
FASEB J.
2011
25:1934-42
PubMed ID: 21368103
DOI: 10.1096/fj.10-175158
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Tamboli IY, Hampel H, Tien NT, Tolksdorf K, Breiden B, Mathews PM, Saftig P, Sandhoff K, Walter J.
Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.
J. Neurosci.
2011
31:1837-49
PubMed ID: 21289194
DOI: 10.1523/JNEUROSCI.2954-10.2011
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9148
Chengqun Huang, Allen M Andres, Eric P Ratliff, Genaro Hernandez, Pamela Lee, Roberta A Gottlieb
Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1
PLoS One
2011
6 (6), e20975
PubMed ID: 21687634
DOI: 10.1371/journal.pone.0020975
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9152
Natura Myeku, Maria E Figueiredo-Pereira
Dynamics of the Degradation of Ubiquitinated Proteins by Proteasomes and Autophagy: Association With Sequestosome 1/p62
J Biol Chem
2011
286 (25), 22426-40
PubMed ID: 21536669
DOI: 10.1074/jbc.M110.149252
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9163
Amy Colleran 1, Aideen Ryan, Angela O'Gorman, Coralie Mureau, Catherine Liptrot, Peter Dockery, Howard Fearnhead, Laurence J Egan
Autophagosomal IkappaB Alpha Degradation Plays a Role in the Long Term Control of Tumor Necrosis Factor-Alpha-Induced Nuclear factor-kappaB (NF-kappaB) Activity
J Biol Chem
2011
286 (26), 22886-93
PubMed ID: 21454695
DOI: 10.1074/jbc.M110.199950
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8269
Eng KE, Panas MD, Karlsson Hedestam GB, McInerney GM.
A novel quantitative flow cytometry-based assay for autophagy.
Autophagy
2010
6:634-41
PubMed ID: 20458170
DOI: 10.4161/auto.6.5.12112
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9178
Srikanth Chiliveru, Svend Birkelund, Søren R Paludan
Induction of Interferon-Stimulated Genes by Chlamydia Pneumoniae in Fibroblasts Is Mediated by Intracellular Nucleotide-Sensing Receptors
PLoS One
2010
5 (4), e10005
PubMed ID: 20386592
DOI: 10.1371/journal.pone.0010005
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