CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB2657 : Colon-26]

5251 Corbett TH, Griswold DP Jr, Roberts BJ, Peckham JC, Schabel FM Jr. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res 1975 35(9):2434-9 PubMed ID: 1149045

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21876 Kawaguchi Y, Terada S, Futaki S. An approach for the intracellular delivery of IgG via enzymatic ligation with a cell-permeable attenuated cationic amphiphilic lytic peptide. Bioorg Med Chem 2024 111:117835 PubMed ID: 39053075 DOI: 10.1016/j.bmc.2024.117835

21933 Okugawa Y, Shirai Y, Fukumori K, Kitajima T, Shimura T, Imaoka H, Kawamura M, Yasuda H, Morimoto Y, Fujiwara T, Mochiki I, Okita Y, Yoshiyama S, Nahata M, Mogami S, Fujitsuka N, Ohi M, Tanaka K, Toiyama Y. Effect of the Japanese herbal medicine Hochuekkito for systemic inflammation, prognostic nutrition index, and body composition status in patients with gastrointestinal cancer. Clin Nutr ESPEN 2024 PubMed ID: 39153597 DOI: 10.1016/j.clnesp.2024.08.004

22244 Yamada S, Sasaki E, Ohno H, Hanaoka K. Heat-guided drug delivery via thermally induced crosslinking of polymeric micelles. Commun Chem 2024 7(1):287 PubMed ID: 39627351 DOI: 10.1038/s42004-024-01383-0

17687 Nomura S, Sukowati EW, Shigeno Y, Takahashi M, Kato A, Benno Y, Yamashita F, Mukai H. Blautia coccoides JCM1395T Achieved Intratumoral Growth with Minimal Inflammation: Evidence for Live Bacterial Therapeutic Potential by an Optimized Sample Preparation and Colony PCR Method Pharmaceutics 2023 15(3):989 PubMed ID: 36986850 DOI: 10.3390/pharmaceutics15030989

19552 Junrong Yang Dynamic Effects of Ketogenic Diet on Autophagy and Cell Cycle in a Mouse Model of CT26+ Colon Cancer Pakistan Journal of Zoology 2023 DOI: 10.17582/journal.pjz/20230222080203

19577 Tamura A, Osawa M, Yui N. Supermolecule-Drug Conjugates Based on Acid-Degradable Polyrotaxanes for pH-Dependent Intracellular Release of Doxorubicin Molecules 2023 28(6):2517 PubMed ID: 36985487 DOI: 10.3390/molecules28062517

19961 Komatsu Y, Yoshitomi T, Doan VTH, Kurokawa H, Fujiwara S, Kawazoe N, Chen G, Matsui H. Locally Administered Photodynamic Therapy for Cancer Using Nano-Adhesive Photosensitizer Pharmaceutics 2023 15(8):2076 PubMed ID: 37631290 DOI: 10.3390/pharmaceutics15082076

21004 Takemoto K, Hao L, Narukawa T, Iji M, Koyama T, Watanabe H. Inhibition of Colorectal Cancer Cell Proliferation by Treatment with Itadori Leaf Extract. J Oleo Sci 2023 PubMed ID: 36631102 DOI: 10.5650/jos.ess22245

21066 Ferdaos N, Harada A, Masuda E, Kasai S, Horaguchi T, Yoshizawa K. Caffeine-Supplemented Diet Prevents Fatigue-Like Behavior in Tumor-Bearing Mice. Nutr Cancer 2023 PubMed ID: 36714982 DOI: 10.1080/01635581.2022.2163669

21076 Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K. Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy. Cancer Med 2023 PubMed ID: 36808261 DOI: 10.1002/cam4.5696

21152 Fukuta T, Ikeda-Imafuku M, Kodama S, Kuse J, Matsui K, Iwao Y. One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique. Pharmaceuticals (Basel) 2023 16(1) PubMed ID: 36678605 DOI: 10.3390/ph16010108

21182 Tsubaki M, Takeda T, Matsuda T, Kishimoto K, Takefuji H, Taniwaki Y, Ueda M, Hoshida T, Tanabe K, Nishida S. Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy. Cancer Cell Int 2023 23(1):73 PubMed ID: 37069612 DOI: 10.1186/s12935-023-02884-z

21250 Miyazaki M, Sawada A, Sawamura D, Yoshida S. Decreased insulin-like growth factor-1 expression in response to mechanical loading is associated with skeletal muscle anabolic resistance in cancer cachexia. Growth Horm IGF Res 2023 69-70:101536 PubMed ID: 37229943 DOI: 10.1016/j.ghir.2023.101536

21411 Asano H, Elhelaly AE, Hyodo F, Iwasaki R, Noda Y, Kato H, Ichihashi K, Tomita H, Murata M, Mori T, Matsuo M. Deuterium Magnetic Resonance Imaging Using Deuterated Water-Induced 2H-Tissue Labeling Allows Monitoring Cancer Treatment at Clinical Field Strength. Clin Cancer Res 2023 PubMed ID: 37732903 DOI: 10.1158/1078-0432.CCR-23-1635

21425 Kametaka S, Isobe M, Komata K, Morinaga M, Nagahata K, Lee-Hotta S, Uchiyama Y, Shibata M, Sugiura H. Protective effects of hachimijiogan (HJG), a Japanese Kampo medicine, on cancer cachectic muscle wasting in mice. Biomed Res 2023 44(5):199-207 PubMed ID: 37779032 DOI: 10.2220/biomedres.44.199

22307 Zhang H, Xie L, Zhang N, Qi X, Lu T, Xing J, Akhtar MF, Li L, Liu G. Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice Genes (Basel) 2023 14(5):1024 PubMed ID: 37239383 DOI: 10.3390/genes14051024

17519 Hama S, Nishi T, Isono E, Itakura S, Yoshikawa Y, Nishimoto A, Suzuki S, Kirimura N, Todo H, Kogure K. Intraperitoneal administration of nanoparticles containing tocopheryl succinate prevents peritoneal dissemination Cancer Sci 2022 113(5):1779-1788 PubMed ID: 35253340 DOI: 10.1111/cas.15321

17523 Sakamoto Y, Suehiro F, Akiba I, Nishimura T. Supramolecular Shear-Thinning Glycopeptide Hydrogels for Injectable Enzyme Prodrug Therapy Applications Langmuir 2022 38(18):5883-5890 PubMed ID: 35471982 DOI: 10.1021/acs.langmuir.2c00504

17665 Masayuki Munekane, Asami Kosugi, Mizuho Yamasaki, Yoko Watanabe, Kento Kannaka, Kohei Sano, Toshihide Yamasaki, Ken-ichi Ogawara, Takahiro Mukai Biodistribution study of indium-111-labeled PEGylated niosomes as novel drug carriers for tumor-targeting Journal of Drug Delivery Science and Technology 2022 75:103648 DOI: 10.1016/j.jddst.2022.103648

17674 Ando H, Ikeda A, Tagami M, Matsuo NCA, Shimizu T, Ishima Y, Eshima K, Ishida T. Oral administration of sodium bicarbonate can enhance the therapeutic outcome of Doxil® via neutralizing the acidic tumor microenvironment J Control Release 2022 350:414-420 PubMed ID: 35988781 DOI: 10.1016/j.jconrel.2022.08.031

19514 Huu Hoang T, Sato-Matsubara M, Yuasa H, Matsubara T, Thuy LTT, Ikenaga H, Phuong DM, Hanh NV, Hieu VN, Hoang DV, Hai H, Okina Y, Enomoto M, Tamori A, Daikoku A, Urushima H, Ikeda K, Dat NQ, Yasui Y, Shinkawa H, Kubo S, Yamagishi R, Ohtani N, Yoshizato K, Gracia-Sancho J, Kawada N. Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms Sci Adv 2022 8(39):eabo5525 PubMed ID: 36170363 DOI: 10.1126/sciadv.abo5525

19521 Okada H, Takahashi K, Yaku H, Kobiyama K, Iwaisako K, Zhao X, Shiokawa M, Uza N, Kodama Y, Ishii KJ, Seno H. In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy Sci Rep 2022 12(1):2132 PubMed ID: 35136110 DOI: 10.1038/s41598-022-05702-0

19530 Hu D, Fumoto S, Miyamoto H, Tanaka M, Nishida K. Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation Pharmaceutics 2022 14(6):1203 PubMed ID: 35745776 DOI: 10.3390/pharmaceutics14061203

20380 Ma L, Sakamoto Y, Ando K, Fujita H, Takahashi A, Takeshima T, Otsuka H, Ebner DK, Kakimi K, Imai T, Shimokawa T. Th balance related host genetic background affects the therapeutic effects of combining carbon-ion radiotherapy with dendritic cell immunotherapy. Int J Radiat Oncol Biol Phys 2022 PubMed ID: 34740767 DOI: 10.1016/j.ijrobp.2021.10.141

20736 Šubr V, Pola R, Gao S, Islam R, Hirata T, Miyake D, Koshino K, Zhou JR, Yokomizo K, Fang J, Etrych T. Tumor Stimulus-Responsive Biodegradable Diblock Copolymer Conjugates as Efficient Anti-Cancer Nanomedicines. J Pers Med 2022 12(5) PubMed ID: 35629120 DOI: 10.3390/jpm12050698

20741 Warashina S, Zouda M, Mohri K, Wada Y, Maeda K, Watanabe Y, Mukai H. 64Cu-labeling of small extracellular vesicle surfaces via a cross-bridged macrocyclic chelator for pharmacokinetic study by positron emission tomography imaging. Int J Pharm 2022 121968 PubMed ID: 35772573 DOI: 10.1016/j.ijpharm.2022.121968

20791 Uemura M, Hiramoto K, Yoneyama H, Harusawa S, Komeda S. Introduction of Fluorine into Antitumor-Active Dinuclear Platinum(II) Complexes Leads to Modulation of In Vivo Antitumor Activity in Mice. Inorg Chem 2022 PubMed ID: 35876345 DOI: 10.1021/acs.inorgchem.2c01126

17104 El Sayed MM, Shimizu T, Abu Lila AS, Elsadek NE, Emam SE, Alaaeldin E, Kamal A, Sarhan HA, Ando H, Ishima Y, Ishida T. A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes Int J Pharm 2022 615:121539 PubMed ID: 35124114 DOI: 10.1016/j.ijpharm.2022.121539

19517 Nomura TK, Heishima K, Sugito N, Sugawara R, Ueda H, Yukihiro A, Honda R. Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains Cell Chem Biol 2021 28(11):1581-1589.e6 PubMed ID: 33964212 DOI: 10.1016/j.chembiol.2021.04.013

19519 Chen CY, Ueha S, Ishiwata Y, Shichino S, Yokochi S, Yang D, Oppenheim JJ, Ogiwara H, Deshimaru S, Kanno Y, Aoki H, Ogawa T, Shibayama S, Matsushima K. Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8+ T Cells Cancer Immunol Res 2021 9(10):1214-1228 PubMed ID: 34344641 DOI: 10.1158/2326-6066.CIR-21-0265

20139 mam SE, Elsadek NE, Abu Lila AS, Takata H, Kawaguchi Y, Shimizu T, Ando H, Ishima Y, Ishida T. Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice. J Control Release 2021 334:327-334 PubMed ID: 33957196 DOI: 10.1016/j.jconrel.2021.05.001

14342 Ando H, Emam SE, Kawaguchi Y, Shimizu T, Ishima Y, Eshima K, Ishida T. Increasing Tumor Extracellular pH by an Oral Alkalinizing Agent Improves Antitumor Responses of Anti-PD-1 Antibody: Implication of Relationships between Serum Bicarbonate Concentrations, Urinary pH, and Therapeutic Outcomes Biol Pharm Bull 2021 44(6):844-852 PubMed ID: 34078817 DOI: 10.1248/bpb.b21-00076

15150 Morinaga M, Sako N, Isobe M, Lee-Hotta S, Sugiura H, Kametaka S. Aerobic Exercise Ameliorates Cancer Cachexia-Induced Muscle Wasting through Adiponectin Signaling Int J Mol Sci 2021 22(6):3110 PubMed ID: 33803685 DOI: 10.3390/ijms22063110

20320 Kitaoka Y, Miyazaki M, Kikuchi S. Voluntary exercise prevents abnormal muscle mitochondrial morphology in cancer cachexia mice. Physiol Rep 2021 9(16):e15016 PubMed ID: 34427401 DOI: 10.14814/phy2.15016

16067 Lazarova D, Semkova S, Zlateva G, Tatsuya H, Aoki I, Bakalova R. Quantum Sensors To Track Total Redox-Status and Oxidative Stress in Cells and Tissues Using Electron-Paramagnetic Resonance, Magnetic Resonance Imaging, and Optical Imaging Anal Chem 2021 93(5):2828-2837 PubMed ID: 33508934 DOI: 10.1021/acs.analchem.0c04116

16096 Sato Y, Fu Y, Liu H, Lee MY, Shaw MH. Tumor-immune profiling of CT-26 and Colon 26 syngeneic mouse models reveals mechanism of anti-PD-1 response BMC Cancer 2021 21(1):122 PubMed ID: 34774008 DOI: 10.1186/s12885-021-08974-3

16121 Sano K, Ishida Y, Tanaka T, Mizukami T, Nagayama T, Haratake Y, Munekane M, Yamasaki T, Mukai T. Enhanced Delivery of Thermoresponsive Polymer-Based Medicine into Tumors by Using Heat Produced from Gold Nanorods Irradiated with Near-Infrared Light Cancers (Basel) 2021 13(19):5005 PubMed ID: 34638489 DOI: 10.3390/cancers13195005

17865 Akiko OHKI, Yuhki YOKOYAMA, Tomoyo YASUDA, Shihori KOUDA, Satoshi SHIBATA, Yuki SHIMOMURA, Xin WU, Yoshinosuke HAMADA, Seiji MORI, Tsutomu TAKEDA, Kenya MURASE, Susumu TANAKA, Hirofumi YAMAMOTO Determining the Tumor Suppressive Effects of a New Drug Delivery System Loaded with Iron Oxide Nanoparticles Nano Biomedicine 2020 12 DOI: 10.11344/nano.12.43

19339 Zhang N, Liu C, Jin L, Zhang R, Wang T, Wang Q, Chen J, Yang F, Siebert HC, Zheng X. Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer J Agric Food Chem 2020 68(40):11182-11196 PubMed ID: 32786841 DOI: 10.1021/acs.jafc.0c04041

19511 Asato Tonegawa, Atsushi Tamura, Shunyao Zhang, Nobuhiko Yui Hydrophobicity of acyl groups in α-cyclodextrin-threaded polyrotaxanes dominates the formation and stability of self-assembled nanoparticles Polymer 2020 200:122537 DOI: 10.1016/j.polymer.2020.122537

11792 Mimura A, Inaoka Y, Asakawa S, Murase K. A Novel Cellular Imaging Method Using Hemagglutinating Virus of Japan-Envelope (HVJ-E) Vector and Magnetic Particle Imaging. J Nanosci Nanotechnol 2020 PubMed ID: 31492206 DOI: 10.1166/jnn.2020.17322

12327 Mahib MR, Hosojima S, Kushiyama H, Kinoshita T, Shiroishi T, Suda T, Tsuchiya K. Caspase-7 mediates caspase-1-induced apoptosis independently of Bid Microbiol Immunol 2020 64(2):143-152 PubMed ID: 31687791 DOI: 10.1111/1348-0421.12756

13004 Yamada T, Ashida Y, Tatebayashi D, Abe M, Himori K. Cancer Cachexia Induces Preferential Skeletal Muscle Myosin Loss When Combined With Denervation. Front Physiol 2020 PubMed ID: 32425814 DOI: 10.3389/fphys.2020.00445

13266 Nomura S, Takahashi M, Kato AH, Wada Y, Watanabe Y, Yamashita F, Mukai H. Biosorption-based ⁶⁴Cu-labeling of bacteria for pharmacokinetic positron-emission tomography. Int J Pharm 2020 PubMed ID: 33027635 DOI: 10.1016/j.ijpharm.2020.119950

13300 Takayama T, Shimizu T, Lila ASA, Kanazawa Y, Ando H, Ishima Y, Ishida T. Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil^®) in C26 Tumor-Bearing Immunocompetent Mice. Pharmaceutics 2020 PubMed ID: 33086690 DOI: 10.3390/pharmaceutics12100990

13584 Uda RM, Yoshida N, Iwasaki T, Hayashi K. pH-triggered solubility and cytotoxicity changes of malachite green derivatives incorporated in liposomes for killing cancer cells J Mater Chem B 2020 8(36):8242-8248 PubMed ID: 32794526 DOI: 10.1039/d0tb01346c

13603 Imanishi M, Yamakawa Y, Fukushima K, Ikuto R, Maegawa A, Izawa-Ishizawa Y, Horinouchi Y, Kondo M, Kishuku M, Goda M, Zamami Y, Takechi K, Chuma M, Ikeda Y, Tsuchiya K, Fujino H, Tsuneyama K, Ishizawa K. Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model Naunyn Schmiedebergs Arch Pharmacol 2020 393(7):1239-1250. PubMed ID: 32307577 DOI: 10.1007/s00210-020-01859-5

13631 Mei T, Shashni B, Maeda H, Nagasaki Y. Fibrinolytic tissue plasminogen activator installed redox-active nanoparticles (t-PA@iRNP) for cancer therapy Biomaterials 2020 259:120290 PubMed ID: 32829147 DOI: 10.1016/j.biomaterials.2020.120290

15161 Kudláčová J, Kotrchová L, Kostka L, Randárová E, Filipová M, Janoušková O, Fang J, Etrych T. Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study Pharmaceutics 2020 12(12):1242 PubMed ID: 33419291 DOI: 10.3390/pharmaceutics12121242

11341 Fukuda T, Nanjo Y, Fujimoto M, Yoshida K, Natsui Y, Ishibashi F, Okazaki F, To H, Iwao M. Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold. Bioorg. Med. Chem. 2019 PubMed ID: 30553626 DOI: 10.1016/j.bmc.2018.11.037

4573 Hatai M, Horiyama S, Yoshikawa N, Kinoshita E, Kagota S, Shinozuka K, Nakamura K. trans-2-Pentenal, an Active Compound in Cigarette Smoke, Identified via Its Ability to Form Adducts with Glutathione. Chem Pharm Bull (Tokyo) 2019 67(9):1000-1005 PubMed ID: 31474722 DOI: 10.1248/cpb.c19-00345

11506 Hayashi K, Watanabe M, Iwasaki T, Shudou M, Uda RM. Endosomal escape by photo-activated fusion of liposomes containing a malachite green derivative: a novel class of photoresponsive liposomes for drug delivery vehicles. Photochem. Photobiol. Sci. 2019 PubMed ID: 30964475 DOI: 10.1039/c8pp00495a

11530 Uda RM, Nishimoto N, Matsui T, Takagi S. Photoinduced binding of malachite green copolymer to parallel G-quadruplex DNA. Soft Matter 2019 PubMed ID: 31073583 DOI: 10.1039/c9sm00411d

11539 Suzuka H, Mimura A, Inaoka Y, Murase K. Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging. J Nanosci Nanotechnol 2019 PubMed ID: 31039837 DOI: 10.1166/jnn.2019.16619

11546 Tsuchiya K, Nakajima S, Hosojima S, Thi Nguyen D, Hattori T, Manh Le T, Hori O, Mahib MR, Yamaguchi Y, Miura M, Kinoshita T, Kushiyama H, Sakurai M, Shiroishi T, Suda T. Caspase-1 initiates apoptosis in the absence of gasdermin D. Nat Commun 2019 PubMed ID: 31064994 DOI: 10.1038/s41467-019-09753-2

11847 Matsui S, Kataoka H, Tanaka JI, Kikuchi M, Fukamachi H, Morisaki H, Matsushima H, Mishima K, Hironaka S, Takaki T, Okahashi N, Maruoka Y, Kuwata H. Dysregulation of intestinal microbiota elicited by food allergy induces IgA-mediated oral dysbiosis. Infect. Immun. 2019 PubMed ID: 31611274 DOI: 10.1128/IAI.00741-19

11859 Emam SE, Selim Abu Lila A, Elsadek NE, Ando H, Shimizu T, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Ishid T. Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues. Eur J Pharm Biopharm 2019 PubMed ID: 31629787 DOI: 10.1016/j.ejpb.2019.10.005

9811 Eiji Kasumi, Norifumi Sato A Ketogenic Diet Improves the Prognosis in a Mouse Model of Peritoneal Dissemination Without Tumor Regression J Clin Biochem Nutr 2019 64(3):201-208 PubMed ID: 31138953 DOI: 10.3164/jcbn.18-103

10421 Yoshimi Inaoka, Tamami Keii, Atsushi Mimura, Kenya Murase A Novel Therapeutic Strategy Combining Use of Intracellular Magnetic Nanoparticles under an Alternating Magnetic Field and Bleomycin Open Journal of Applied Sciences 2019 9, Article ID:91110,17 DOI: 10.4236/ojapps.2019.93008

10589 Seiji Komeda, Masako Uemura, Hiroki Yoneyama, Shinya Harusawa and Keiichi Hiramoto In Vitro Cytotoxicity and In Vivo Antitumor Efficacy of Tetrazolato-Bridged Dinuclear Platinum(II) Complexes with a Bulky Substituent at Tetrazole C5 Inorganics 2019 7(1):5 DOI: 10.3390/inorganics7010005

12407 Peng JQ, Fumoto S, Suga T, Miyamoto H, Kuroda N, Kawakami S, Nishida K. Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles J Control Release 2019 302:42-53 PubMed ID: 30926479 DOI: 10.1016/j.jconrel.2019.03.021

12408 Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells Cancer Sci 2019 110(10):3027-3037 PubMed ID: 31348591 DOI: 10.1111/cas.14144

12409 Yamamoto S, Yamashita T, Ito M, Caaveiro JMM, Egashira N, Tozaki-Saitoh H, Tsuda M. New pharmacological effect of fulvestrant to prevent oxaliplatin-induced neurodegeneration and mechanical allodynia in rats Int J Cancer 2019 145(8):2107-2113 PubMed ID: 30515800 DOI: 10.1002/ijc.32043

10546 Miyamoto H, Tsujimoto H, Horii T, Ozamoto Y, Ueda J, Takagi T, Saitoh N, Hagiwara A. The influences of a novel anti-adhesion device, thermally cross-linked gelatin film on peritoneal dissemination of tumor cells: The in vitro and in vivo experiments using murine carcinomatous peritonitis models. J. Biomed. Mater. Res. Part B Appl. Biomater. 2018 106(6):2122-2130 PubMed ID: 29024447 DOI: 10.1002/jbm.b.34017

10733 Kawami M, Yamada Y, Issarachot O, Junyaprasert VB, Yumoto R, Takano M. P-gp modulating effect of Azadirachta indica extract in multidrug-resistant cancer cell lines. Pharmazie 2018 73:104-109 PubMed ID: 29442013 DOI: 10.1691/ph.2018.7116

10746 Miura K, Haraguchi M, Ito H, Tai A. Potential Antitumor Activity of 2-O-α-d-Glucopyranosyl-6-O-(2-Pentylheptanoyl)-l-Ascorbic Acid. Int J Mol Sci 2018 19: PubMed ID: 29439410 DOI: 10.3390/ijms19020535

10772 Morio H, Sun Y, Harada M, Ide H, Shimozato O, Zhou X, Higashi K, Yuki R, Yamaguchi N, Hofbauer JP, Guttmann-Gruber C, Anzai N, Akita H, Chiba K, Furihata T. Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker. Biol. Pharm. Bull. 2018 41:445-449 PubMed ID: 29491222 DOI: 10.1248/bpb.b17-00743

10827 Hatai M, Yoshikawa N, Kinoshita E, Horiyama S, Kagota S, Shinozuka K, Nakamura K. Invasion-inhibiting Effects of Gaseous Components in Cigarette Smoke on Mouse Rectal Carcinoma Colon-26 Cells. In Vivo 2018 32:493-497 PubMed ID: 29695551 DOI: 10.21873/invivo.11266

10831 Emam SE, Ando H, Abu Lila AS, Shimizu T, Ukawa M, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Ishida T. A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research. Biol. Pharm. Bull. 2018 41:733-742 PubMed ID: 29709910 DOI: 10.1248/bpb.b17-00919

11060 Hayashi K, Mitsuyoshi Y, Kamei T, Shimanouchi T, Suga K, Okamoto Y, Nakamura H, Umakoshi H. Design of Pyrene–Fatty Acid Conjugates for Real-Time Monitoring of Drug Delivery and Controllability of Drug Release ACS Omega 2018 3:3572-3580 PubMed ID: 30023872 DOI: 10.1021/acsomega.7b02061

11199 Kuroda K, Yamashita M, Murahata Y, Azuma K, Osaki T, Tsuka T, Ito N, Imagawa T, Okamoto Y. Use of ozonated water as a new therapeutic approach to solve current concerns around antitumor treatment. Exp Ther Med 2018 16(3):1597-1602 PubMed ID: 30186377 DOI: 10.3892/etm.2018.6415

11187 Noji M, So M, Yamaguchi K, Hojo H, Onda M, Akazawa-Ogawa Y, Hagihara Y, Goto Y. Heat-Induced Aggregation of Hen Ovalbumin Suggests a Key Factor Responsible for Serpin Polymerization. Biochemistry 2018 57(37):5415-5426 PubMed ID: 30148614 DOI: 10.1021/acs.biochem.8b00619

11224 Emam SE, Ando H, Lila ASA, Shimizu T, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Sagawa I, Ishida T. Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways. Sci Rep 2018 PubMed ID: 30262875 DOI: 10.1038/s41598-018-32861-w

4079 Yuba E, Osaki T, Ono M, Park S, Harada A, Yamashita M, Azuma K, Tsuka T, Ito N, Imagawa T, Okamoto Y. Bleomycin-Loaded pH-Sensitive Polymer–Lipid-Incorporated Liposomes for Cancer Chemotherapy Polymers 2018 10, 74 PubMed ID: 30966109 DOI: 10.3390/polym10010074

4179 Tatebayashi D, Himori K, Yamada R, Ashida Y, Miyazaki M, Yamada T. High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice. PLoS ONE 2018 PubMed ID: 29894511 DOI: 10.1371/journal.pone.0199050

14600 Sano K, Kanada Y, Takahashi K, Ding N, Kanazaki K, Mukai T, Ono M, Saji H. Enhanced Delivery of Radiolabeled Polyoxazoline into Tumors via Self-Aggregation under Hyperthermic Conditions Mol Pharm 2018 15(9):3997-4003 PubMed ID: 30036483 DOI: 10.1021/acs.molpharmaceut.8b00441

10278 Miura K, Tai A. 2-O-α-D-Glucopyranosyl-l-ascorbic acid as an antitumor agent for infusion therapy. Biochem Biophys Rep 2017 10:232-236 PubMed ID: 28955751 DOI: 10.1016/j.bbrep.2017.04.014

10424 Maeda M, Muragaki Y, Okamoto J, Yoshizawa S, Abe N, Nakamoto H, Ishii H, Kawabata K, Umemura S, Nishiyama N, Kataoka K, Iseki H. Sonodynamic Therapy Based on Combined Use of Low Dose Administration of Epirubicin-Incorporating Drug Delivery System and Focused Ultrasound. Ultrasound Med Biol 2017 43:2295-2301 PubMed ID: 28705555 DOI: 10.1016/j.ultrasmedbio.2017.06.003

10545 Ikemura M, Hashida T. Effect of Hyperglycemia on Antitumor Activity and Survival in Tumor-bearing Mice Receiving Oxaliplatin and Fluorouracil. Anticancer Res. 2017 37:5463-5468 PubMed ID: 28982857 DOI: 10.21873/anticanres.11975

10991 AKIKO OHKI, MINORI TANOUE, SAYUMI KOBAYASHI, KENYA MURASE Magnetic Particle Imaging for Quantitative Evaluation of Tumor Response to Magnetic Hyperthermia Treatment Combined with Chemotherapy Using Cisplatin Thermal Medicine 2017 33, 39-51 DOI: 10.3191/thermalmed.33.39

11017 Comparative Study of Extracellular and Intracellular Magnetic Hyperthermia Treatments Using Magnetic Particle Imaging Open Journal of Applied Sciences 2017 7, 647-660 DOI: 10.4236/ojapps.2017.712047

5395 Kokuryo D, Aoki I, Yuba E, Kono K, Aoshima S, Kershaw J, Saga T. Evaluation of a combination tumor treatment using thermo-triggered liposomal drug delivery and carbon ion irradiation. Transl Res 2017 185:24-33 PubMed ID: 28482173 DOI: 10.1016/j.trsl.2017.04.001

10855 Shimaoka H, Takeno S, Maki K, Sasaki T, Hasegawa S, Yamashita Y. A cytokine signal inhibitor for rheumatoid arthritis enhances cancer metastasis via depletion of NK cells in an experimental lung metastasis mouse model of colon cancer Oncol Lett 2017 14(3):3019-3027 PubMed ID: 28928840 DOI: 10.3892/ol.2017.6473

14669 Gao Z, Nakanishi Y, Noda S, Omachi H, Shinohara H, Kimura H, Nagasaki Y. Development of Gd 3 N@C 80 encapsulated redox nanoparticles for high-performance magnetic resonance imaging J Biomater Sci Polym Ed 2017 28(10-12):1036-1050 PubMed ID: 28132586 DOI: 10.1080/09205063.2017.1288774

14719 Sano K, Ohashi M, Kanazaki K, Makino A, Ding N, Deguchi J, Kanada Y, Ono M, Saji H. Indocyanine Green-Labeled Polysarcosine for in Vivo Photoacoustic Tumor Imaging Bioconjug Chem 2017 28(4):1024-1030 PubMed ID: 28166625 DOI: 10.1021/acs.bioconjchem.6b00715

14720 Ohyama A, Higashi T, Motoyama K, Arima H. Ternary complexes of folate-PEG-appended dendrimer (G4)/α-cyclodextrin conjugate, siRNA and low-molecular-weight polysaccharide sacran as a novel tumor-selective siRNA delivery system Int J Biol Macromol 2017 99:21-28 PubMed ID: 28223132 DOI: 10.1016/j.ijbiomac.2017.02.045

14721 Miki K, Enomoto A, Inoue T, Nabeshima T, Saino S, Shimizu S, Matsuoka H, Ohe K. Polymeric Self-Assemblies with Boron-Containing Near-Infrared Dye Dimers for Photoacoustic Imaging Probes Biomacromolecules 2017 18(1):249-256 PubMed ID: 27936606 DOI: 10.1021/acs.biomac.6b01568

14722 Kanemaru H, Yamane F, Fukushima K, Matsuki T, Kawasaki T, Ebina I, Kuniyoshi K, Tanaka H, Maruyama K, Maeda K, Satoh T, Akira S. Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages Proc Natl Acad Sci U S A 2017 114(35):E7331-E7340 PubMed ID: 28808017 DOI: 10.1073/pnas.1708598114

14736 Takara K, Eino D, Ando K, Yasuda D, Naito H, Tsukada Y, Iba T, Wakabayashi T, Muramatsu F, Kidoya H, Fukuhara S, Mochizuki N, Ishii S, Kishima H, Takakura N. Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact Cell Rep 2017 20(9):2072-2086 PubMed ID: 28854359 DOI: 10.1016/j.celrep.2017.07.080

14748 Yamamoto S, Ushio S, Egashira N, Kawashiri T, Mitsuyasu S, Higuchi H, Ozawa N, Masuguchi K, Ono Y, Masuda S. Excessive spinal glutamate transmission is involved in oxaliplatin-induced mechanical allodynia: a possibility for riluzole as a prophylactic drug Sci Rep 2017 7(1):9661 PubMed ID: 28851920 DOI: 10.1038/s41598-017-08891-1

7141 Vong LB, Nagasaki Y. Combination Treatment of Murine Colon Cancer with Doxorubicin and Redox Nanoparticles. Mol. Pharm. 2016 13:449-55 PubMed ID: 26605906 DOI: 10.1021/acs.molpharmaceut.5b00676

7209 Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y. Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate. Ultrason Sonochem 2016 28:161-168 PubMed ID: 26384895 DOI: 10.1016/j.ultsonch.2015.07.013

9507 Ohyama A, Higashi T, Motoyama K, Arima H. In Vitro and In Vivo Tumor-Targeting siRNA Delivery Using Folate-PEG-appended Dendrimer (G4)/α-Cyclodextrin Conjugates. Bioconjug. Chem. 2016 27:521-32 PubMed ID: 26715308 DOI: 10.1021/acs.bioconjchem.5b00545

9753 Gao Z, Horiguchi Y, Nakai K, Matsumura A, Suzuki M, Ono K, Nagasaki Y. Use of boron cluster-containing redox nanoparticles with ROS scavenging ability in boron neutron capture therapy to achieve high therapeutic efficiency and low adverse effects. Biomaterials 2016 104:201-12 PubMed ID: 27467416 DOI: 10.1016/j.biomaterials.2016.06.046

9856 Kanazaki K, Sano K, Makino A, Homma T, Ono M, Saji H. Polyoxazoline multivalently conjugated with indocyanine green for sensitive in vivo photoacoustic imaging of tumors. Sci Rep 2016 6:33798 PubMed ID: 27667374 DOI: 10.1038/srep33798

9995 Yamano T, Kubo S, Fukumoto M, Yano A, Mawatari-Furukawa Y, Okamura H, Tomita N. Whole cell vaccination using immunogenic cell death by an oncolytic adenovirus is effective against a colorectal cancer model. Mol Ther Oncolytics 2016 3:16031 PubMed ID: 28035331 DOI: 10.1038/mto.2016.31

10859 Tomomi Kuboyabu, Isamu Yabata, Marina Aoki, Natsuo Banura, Kohei Nishimoto, Atsushi Mimura, Kenya Murase Magnetic Particle Imaging for Magnetic Hyperthermia Treatment: Visualization and Quantification of the Intratumoral Distribution and Temporal Change of Magnetic Nanoparticles in Vivo Open Journal of Medical Imaging 2016 6:1-15 DOI: 10.4236/ojmi.2016.61001

10896 Tomomi Kuboyabu, Mikiko Yamawaki, Marina Aoki, Akiko Ohki, Kenya Murase Quantitative Evaluation of Tumor Early Response to Magnetic Hyperthermia combined with Vascular Disrupting Therapy using Magnetic Particle Imaging International Journal of Nanomedicine and Nanosurgery 2016 2.3 DOI: 10.16966/2470-3206.114

12406 Akiko Ohki, Tomomi Kuboyabu, Marina Aoki, Mikiko Yamawaki, Kenya Murase Quantitative Evaluation of Tumor Response to combination of Magnetic Hyperthermia Treatment and Radiation Therapy using Magnetic Particle Imaging Int J Nanomed Nanosurg 2016 2.3 DOI: 10.16966/2470-3206.117

12691 Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K. Tumor growth suppression by the combination of nanobubbles and ultrasound Cancer Sci 2016 107(3):217-23 PubMed ID: 26707839 DOI: 10.1111/cas.12867

14132 Okazaki F, Matsunaga N, Okazaki H, Azuma H, Hamamura K, Tsuruta A, Tsurudome Y, Ogino T, Hara Y, Suzuki T, Hyodo K, Ishihara H, Kikuchi H, To H, Aramaki H, Koyanagi S, Ohdo S. Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression J Biol Chem 2016 291(13):7017-28 PubMed ID: 26797126 DOI: 10.1074/jbc.M115.713412

17834 Kurokawa H, Ito H, Inoue M, Tabata K, Sato Y, Yamagata K, Kizaka-Kondoh S, Kadonosono T, Yano S, Inoue M, Kamachi T. High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime Sci Rep 2015 5:10657 PubMed ID: 26065366 DOI: 10.1038/srep10657

7116 Hayashi K, Kiriishi M, Suga K, Okamoto Y, Umakoshi H. Investigation of Fatty Acid Ketohydrazone Modified Liposome's Properties as a Drug Carrier. J Drug Deliv 2015 2015:481670 PubMed ID: 26649201 DOI: 10.1155/2015/481670

7167 Kuroda K, Azuma K, Mori T, Kawamoto K, Murahata Y, Tsuka T, Osaki T, Ito N, Imagawa T, Itoh F, Okamoto Y. The Safety and Anti-Tumor Effects of Ozonated Water in Vivo. Int J Mol Sci 2015 16:25108-20 PubMed ID: 26506343 DOI: 10.3390/ijms161025108

7195 Narayanan NK, Kunimasa K, Yamori Y, Mori M, Mori H, Nakamura K, Miller G, Manne U, Tiwari AK, Narayanan B. Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo. Cancer Med 2015 4:1767-80 PubMed ID: 26408414 DOI: 10.1002/cam4.520

7261 Aikawa T, Ito S, Shinohara M, Kaneko M, Kondo T, Yuasa M. A drug formulation using an alginate hydrogel matrix for efficient oral delivery of the manganese porphyrin-based superoxide dismutase mimic. Biomater Sci 2015 3:861-9 PubMed ID: 26221846 DOI: 10.1039/c5bm00056d

7364 Arai Y, Yamamoto T, Minamikawa T, Takamatsu T, Nagai T. Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy. PLoS ONE 2015 10:e0125733 PubMed ID: 25950513 DOI: 10.1371/journal.pone.0125733

7366 Vong LB, Yoshitomi T, Matsui H, Nagasaki Y. Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer. Biomaterials 2015 55:54-63 PubMed ID: 25934452 DOI: 10.1016/j.biomaterials.2015.03.037

7555 Ryota Araki, Shoji Nishida, Yosuke Hiraki, Takeshi Yabe Kamikihito ameliorates tumor‐induced sickness behavior in mice. Traditional & Kampo Medicine 2015 2:93-96 DOI: 10.1002/tkm2.1025

7571 Y. Miura, A. B. Tsuji, A. Sugyo, H. Sudo, I. Aoki, M. Inubushi, M. Yashiro, K. Hirakawa, H. Cabral, N. Nishiyama, T. Saga, K. Kataoka Polymeric Micelle Platform for Multimodal Tomographic Imaging to Detect Scirrhous Gastric Cancer. ACS Biomater Sci Eng 2015 1:1067?1076 PubMed ID: 33429548 DOI: 10.1021/acsbiomaterials.5b00142

12246 Kaori Miura, Futoshi Yazama, Akihiro Tai Oxidative stress-mediated antitumor activity of erythorbic acid in high doses Biochem Biophys Rep 2015 3:117-122 PubMed ID: 29124174 DOI: 10.1016/j.bbrep.2015.07.018

15071 Shinya T, Yokota T, Nakayama S, Oki S, Mutoh J, Takahashi S, Sato K. Orally Administered Mucolytic Drug l-Carbocisteine Inhibits Angiogenesis and Tumor Growth in Mice J Pharmacol Exp Ther 2015 354(3):269-78 PubMed ID: 26126534 DOI: 10.1124/jpet.115.224816

11037 Takemura R, Takaki H, Okada S, Shime H, Akazawa T, Oshiumi H, Matsumoto M, Teshima T, Seya T. PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo Cancer Immunol Res 2015 3(8):902-14 PubMed ID: 25898986 DOI: 10.1158/2326-6066.CIR-14-0219

15236 Kudo S, Nagasaki Y. A novel nitric oxide-based anticancer therapeutics by macrophage-targeted poly(l-arginine)-based nanoparticles J Control Release 2015 217:256-62 PubMed ID: 26386436 DOI: 10.1016/j.jconrel.2015.09.019

15437 Miki K, Inoue T, Kobayashi Y, Nakano K, Matsuoka H, Yamauchi F, Yano T, Ohe K. Near-infrared dye-conjugated amphiphilic hyaluronic acid derivatives as a dual contrast agent for in vivo optical and photoacoustic tumor imaging Biomacromolecules 2015 16(1):219-27 PubMed ID: 25402751 DOI: 10.1021/bm501438e

15481 Fujita S, Ushio S, Ozawa N, Masuguchi K, Kawashiri T, Oishi R, Egashira N. Exenatide Facilitates Recovery from Oxaliplatin-Induced Peripheral Neuropathy in Rats PLoS One 2015 10(11):e0141921 PubMed ID: 26536615 DOI: 10.1371/journal.pone.0141921

19513 Kanazaki K, Sano K, Makino A, Takahashi A, Deguchi J, Ohashi M, Temma T, Ono M, Saji H. Development of human serum albumin conjugated with near-infrared dye for photoacoustic tumor imaging J Biomed Opt 2014 19(9):96002. PubMed ID: 25191833 DOI: 10.1117/1.JBO.19.9.096002

19515 Abdelwahab AF, Ohyama A, Higashi T, Motoyama K, Khaled KA, Sarhan HA, Hussein AK, Arima H. Preparation and evaluation of polyamidoamine dendrimer conjugate with glucuronylglucosyl-β-cyclodextrin (G3) as a novel carrier for siRNA J Drug Target 2014 22(10):927-34 PubMed ID: 25148608 DOI: 10.3109/1061186X.2014.950663

19516 Motoyama K, Mitsuyasu R, Akao C, Tanaka T, Ohyama A, Sato N, Higashi T, Arima H. Design and evaluation of thioalkylated mannose-modified dendrimer (G3)/α-cyclodextrin conjugates as antigen-presenting cell-selective siRNA carriers AAPS J 2014 16(6):1298-308 PubMed ID: 25236864 DOI: 10.1208/s12248-014-9665-9

19523 Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M. In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages Biol Pharm Bull 2014 37(1):137-44 PubMed ID: 24141263 DOI: 10.1248/bpb.b13-00659

19524 Migita K, Sho M, Shimada K, Yasuda S, Yamato I, Takayama T, Matsumoto S, Wakatsuki K, Hotta K, Tanaka T, Ito M, Konishi N, Nakajima Y. Significant involvement of herpesvirus entry mediator in human esophageal squamous cell carcinoma Cancer 2014 120(6):808-17. PubMed ID: 24249528 DOI: 10.1002/cncr.28491

15819 Gong ZY, Kidoya H, Mohri T, Han Y, Takakura N. DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells PLoS One 2014 21;9(10):e110483 PubMed ID: 25334017 DOI: 10.1371/journal.pone.0110483

16092 Hałupka-Bryl M, Asai K, Thangavel S, Bednarowicz M, Krzyminiewski R, Nagasaki Y. Synthesis and in vitro and in vivo evaluations of poly(ethylene glycol)-block-poly(4-vinylbenzylphosphonate) magnetic nanoparticles containing doxorubicin as a potential targeted drug delivery system Colloids Surf B Biointerfaces 2014 118:140-7 PubMed ID: 24769390 DOI: 10.1016/j.colsurfb.2014.03.025

16093 Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice J Drug Target 2014 22(5):439-49 PubMed ID: 24579693 DOI: 10.3109/1061186X.2014.880443

17153 Haga E, Endo Y, Haruta M, Koba C, Matsumura K, Takamatsu K, Ikeda T, Nishimura Y, Senju S. Therapy of peritoneally disseminated colon cancer by TAP-deficient embryonic stem cell-derived macrophages in allogeneic recipients J Immunol 2014 193(4):2024-33 PubMed ID: 25031460 DOI: 10.4049/jimmunol.1303473

18594 Yasuda S, Sho M, Yamato I, Yoshiji H, Wakatsuki K, Nishiwada S, Yagita H, Nakajima Y. Simultaneous blockade of programmed death 1 and vascular endothelial growth factor receptor 2 (VEGFR2) induces synergistic anti-tumour effect in vivo Clin Exp Immunol 2013 172(3):500-6 PubMed ID: 23600839 DOI: 10.1111/cei.12069

19520 Asano R, Nagami A, Fukumoto Y, Yazama F, Ito H, Sakata I, Tai A. Synthesis and biological evaluation of new chlorin derivatives as potential photosensitizers for photodynamic therapy Bioorg Med Chem 2013 21(8):2298-2304 PubMed ID: 23477944 DOI: 10.1016/j.bmc.2013.02.005

19526 Miyauchi E, Ogita T, Miyamoto J, Kawamoto S, Morita H, Ohno H, Suzuki T, Tanabe S. Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis by suppressing IL-17A response: involvement of intestinal epithelial costimulatory molecules PLoS One 2013 8(11):e79735 PubMed ID: 24255712 DOI: 10.1371/journal.pone.0079735

9089 Ryoko Yumoto, Saki Kakizoe, Junya Nagai, Denpong Patanasethanont, Bung-Orn Sripanidkulchai, Mikihisa Takano Flow Cytometry Analysis of Cancer Cell Death Induced by the Extract of Thai Plant Ellipeiopsis Cherrevensis Drug Metab Pharmacokinet 2013 28 (2), 159-63 PubMed ID: 22850758 DOI: 10.2133/dmpk.dmpk-12-nt-056

15985 Kokuryo D, Anraku Y, Kishimura A, Tanaka S, Kano MR, Kershaw J, Nishiyama N, Saga T, Aoki I, Kataoka K. SPIO-PICsome: development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes) J Control Release 2013 169(3):220-7 PubMed ID: 23542239 DOI: 10.1016/j.jconrel.2013.03.016

16084 Murayama S , Jo JI , Shibata Y , Liang K , Santa T , Saga T , Aoki I , Kato M . The simple preparation of polyethylene glycol-based soft nanoparticles containing dual imaging probes J Mater Chem B 2013 1(38):4932-4938 PubMed ID: 32261082 DOI: 10.1039/c3tb20828a

19518 Motoyama K, Hayashida K, Higashi T, Arima H. Polypseudorotaxanes of pegylated α-cyclodextrin/polyamidoamine dendrimer conjugate with cyclodextrins as a sustained release system for DNA Bioorg Med Chem 2012 20(4):1425-33 PubMed ID: 22277591 DOI: 10.1016/j.bmc.2011.12.060

19522 Arima H, Yoshimatsu A, Ikeda H, Ohyama A, Motoyama K, Higashi T, Tsuchiya A, Niidome T, Katayama Y, Hattori K, Takeuchi T. Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier Mol Pharm 2012 9(9):2591-604 PubMed ID: 22873579 DOI: 10.1021/mp300188f

19527 The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy Oncogene 2012 31(27):3254-64 PubMed ID: 22037214 DOI: 10.1038/onc.2011.489

16077 Kei Asai, Naoki Kanayama, Yukio Nagasaki Preparation and evaluation of highly dispersible and Ca2+ level responsive PEGylated calcium phosphate nanoparticle with PEG-block-poly(4-vinylbenzylphosphonate) for the application of drug carrier Transactions of the Materials Research Society of Japan 2012 37:337-340 DOI: 10.14723/tmrsj.37.337

7692 Arima H, Tsutsumi T, Yoshimatsu A, Ikeda H, Motoyama K, Higashi T, Hirayama F, Uekama K. Inhibitory effect of siRNA complexes with polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) on endogenous gene expression. Eur J Pharm Sci 2011 44:375-84 PubMed ID: 21896329 DOI: 10.1016/j.ejps.2011.08.019

7811 Azuma H, Aizawa Y, Higashitani N, Tsumori T, Kojima-Yuasa A, Matsui-Yuasa I, Nagasaki T. Biological activity of water-soluble inclusion complexes of 1'-acetoxychavicol acetate with cyclodextrins. Bioorg. Med. Chem. 2011 19:3855-63 PubMed ID: 21596572 DOI: 10.1016/j.bmc.2011.04.038

19528 Habeeb BS, Kitayama J, Nagawa H. Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells Cancer Sci 2011 102(5):999-1006 PubMed ID: 21299716 DOI: 10.1111/j.1349-7006.2011.01902.x

15358 Yoriki R, Akashi S, Sho M, Nomi T, Yamato I, Hotta K, Takayama T, Matsumoto S, Wakatsuki K, Migita K, Yagita H, Nakajima Y. Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer Exp Ther Med 2011 2(1):103-108 PubMed ID: 22977477 DOI: 10.3892/etm.2010.181

8168 Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T. Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity. Biol. Pharm. Bull. 2010 33:1355-9 PubMed ID: 20686231 DOI: 10.1248/bpb.33.1355

8283 Matsumura K, Bae JY, Hyon SH. Polyampholytes as cryoprotective agents for mammalian cell cryopreservation. Cell Transplant 2010 19(6):691-9 PubMed ID: 20525437 DOI: 10.3727/096368910X508780