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RCB2202 : 293T  update : 2018/07/06
CommentHuman cell line expressing SV40 large T antigen abundantly.
Comment from the depositor
Restriction (Category)a
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Miyoshi, Hiroyuki
Year of deposit 2005
Original cell HEK293
Animal human < Mammals
Genus Homo
Species sapiens
Age at sampling embryo
Tissue kidney
Classification transformed
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM (low glucose) + 10% FBS (heat inactivated)
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 10 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Animal PCR OK
Images
deposit info
lot info
Reference information Reference 0
User's Publication 106


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Reference

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User's Publication
Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.  Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.  Nature  2017  552:101-105  PubMed ID: 29186116
Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.  Five colour variants of bright luminescent protein for real-time multicolour bioimaging.  Nat Commun  2016  7:13718  PubMed ID: 27966527
Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M.  Forward-genetics analysis of sleep in randomly mutagenized mice.  Nature  2016  539:378-383  PubMed ID: 27806374
Kanda S, Yanagitani K, Yokota Y, Esaki Y, Kohno K.  Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E5886-E5895  PubMed ID: 27651490
Hashimoto T, Horikawa DD, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, Toyoda A, Kunieda T.  Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.  Nat Commun  2016  7:12808  PubMed ID: 27649274
Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I.  Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.  Nat. Biotechnol.  2016  34:1060-1065  PubMed ID: 27571369
Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.  Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.  Nature  2016  534:402-6  PubMed ID: 27281199
Ichijo Y, Mochimaru Y, Azuma M, Satou K, Negishi J, Nakakura T, Oshima N, Mogi C, Sato K, Matsuda K, Okajima F, Tomura H.  Two zebrafish G2A homologs activate multiple intracellular signaling pathways in acidic environment.  Biochem. Biophys. Res. Commun.  2015  469:81-86  PubMed ID: 26614909
Hang Q, Isaji T, Hou S, Im S, Fukuda T, Gu J.  Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.  J. Biol. Chem.  2015  290:29345-60  PubMed ID: 26483551
Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S.  Integrated molecular analysis of adult T cell leukemia/lymphoma.  Nat. Genet.  2015  47:1304-15  PubMed ID: 26437031
Aoki N, Yamaguchi S, Kitajima T, Takehara A, Katagiri-Nakagawa S, Matsui R, Watanabe D, Matsushima T, Homma KJ.  Critical role of the neural pathway from the intermediate medial mesopallium to the intermediate hyperpallium apicale in filial imprinting of domestic chicks (Gallus gallus domesticus).  Neuroscience  2015  308:115-24  PubMed ID: 26362886
Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlotzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.  Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.  Lab. Invest.  2015  95:1291-304  PubMed ID: 26302187
Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.  Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.  Sci Rep  2015  5:12841  PubMed ID: 26269411
Kikuta S, Hou BH, Sato R, Frommer WB, Kikawada T.  FRET sensor-based quantification of intracellular trehalose in mammalian cells.  Biosci. Biotechnol. Biochem.  2015  80:162-5  PubMed ID: 26214383
Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.  The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.  Cell. Signal.  2015  27:2087-98  PubMed ID: 26208882
Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638
Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.  Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.  J. Immunol.  2015  194:5426-36  PubMed ID: 25917084
Ito T, Hioki H, Sohn J, Okamoto S, Kaneko T, Iino S, Oliver DL.  Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons.  J. Comp. Neurol.  2015  523:2277-96  PubMed ID: 25879870
Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y.  Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.  J. Cell. Physiol.  2015  230:2510-21  PubMed ID: 25802132
Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.  A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.  PLoS ONE  2015  10:e0120047  PubMed ID: 25781496
Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.  LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.  PLoS ONE  2015  10:e0118662  PubMed ID: 25723520
Mochimaru Y, Azuma M, Oshima N, Ichijo Y, Satou K, Matsuda K, Asaoka Y, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Tomura H.  Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish.  Biochem. Biophys. Res. Commun.  2015  457:493-9  PubMed ID: 25576873
Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.  Participation of the extracellular domain in (pro)renin receptor dimerization.  Biochem. Biophys. Res. Commun.  2014  444:461-6  PubMed ID: 24472541
Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.  Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.  Int. J. Cancer  2011  131:E649-58  PubMed ID: 22109656
Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.  Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.  Microbiol. Immunol.  2011  55:760-7  PubMed ID: 21851384
Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.  Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.  Biochem. Biophys. Res. Commun.  2011  405:620-5  PubMed ID: 21272567
Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.  Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .  Biochemistry  2010  49:6494-503  PubMed ID: 20568732
Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.  The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.  Mol. Cell. Biol.  2010  30:3994-4005  PubMed ID: 20530197
Shigemura T, Shiohara M, Tanaka M, Takeuchi K, Koike K.  Effect of the mutant microphthalmia-associated transcription factor found in Tietz syndrome on the in vitro development of mast cells.  J. Pediatr. Hematol. Oncol.  2010  32:442-7  PubMed ID: 20485200
Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, Ohno M, Nishi K, Eto K, Kimura Y, Nakanishi Y, Ikegami K, Yoshikawa T, Fukuda A, Kawada K, Sakai Y, Ito A, Yoshida M, Kimura T, Chiba T, Nishi E, Seno H.  Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.  JCI Insight  2018  3:  PubMed ID: 29669932
Hagiwara A, Ogiwara K, Takahashi T.  Expression of Membrane Progestin Receptors (mPRs) in Granulosa Cells of Medaka Preovulatory Follicles.  Zool. Sci.  2016  33:98-105  PubMed ID: 26853875
Koguchi T, Tanikawa C, Mori J, Kojima Y, Matsuda K.  Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway.  Int. J. Oncol.  2016  48:2415-24  PubMed ID: 27035231
Tsuchiya M, Niwa Y, Simizu S.  N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/β-catenin signaling-enhancing activity.  Oncol Lett  2016  11:3279-3286  PubMed ID: 27123103
Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett AJ, Yasukawa M.  Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia.  Clin. Cancer Res.  2016  22:4405-16  PubMed ID: 27091408
Hirayasu K, Saito F, Suenaga T, Shida K, Arase N, Oikawa K, Yamaoka T, Murota H, Chibana H, Nakagawa I, Kubori T, Nagai H, Nakamaru Y, Katayama I, Colonna M, Arase H.  Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2.  Nat Microbiol  2016  1:16054  PubMed ID: 27572839
Khanom R, Nguyen CT, Kayamori K, Zhao X, Morita K, Miki Y, Katsube K, Yamaguchi A, Sakamoto K.  Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth.  PLoS ONE  2016  11:e0161163  PubMed ID: 27512993
Yamaura K, Kiyonaka S, Numata T, Inoue R, Hamachi I.  Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.  Nat. Chem. Biol.  2016  12:822-30  PubMed ID: 27526031
Kobayashi T, Yagi Y, Nakamura T.  Development of Genome Engineering Tools from Plant-Specific PPR Proteins Using Animal Cultured Cells.  Methods Mol. Biol.  2016  1469:147-55  PubMed ID: 27557692
Kondoh Y, Honda K, Hiranuma S, Hayashi T, Shimizu T, Watanabe N, Osada H.  Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.  Sci Rep  2016  6:29881  PubMed ID: 27431267
Hazawa M, Yasuda T, Saotome-Nakamura A, Tomiyama K, Obara C, Goto T, Tajima K.  Intra- and extracellular plasminogen activator inhibitor-1 regulate effect of vitronectin against radiation-induced endothelial cell death.  Vascul. Pharmacol.  2016  87:150-158  PubMed ID: 27650166
Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J.  N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.  Sci Rep  2016  6:33507  PubMed ID: 27641064
Kanehira M, Fujiwara T, Nakajima S, Okitsu Y, Onishi Y, Fukuhara N, Ichinohasama R, Okada Y, Harigae H.  An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.  Stem Cells  2017  35:739-753  PubMed ID: 27641212
Chung J, Aburaya S, Aoki W, Ueda M.  Molecular changes in appearance of a cancer cell among normal HEK293T cells.  J. Biosci. Bioeng.  2017  123:281-286  PubMed ID: 27777049
Kurita K, Maeda M, Mansour MA, Kokuryo T, Uehara K, Yokoyama Y, Nagino M, Hamaguchi M, Senga T.  TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion.  Oncol Lett  2016  12:5240-5246  PubMed ID: 28105232
Nishimura T, Ito S, Saito H, Hiver S, Shigetomi K, Ikenouchi J, Takeichi M.  DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.  J. Cell Biol.  2016  215:559-573  PubMed ID: 27807130
Takayama I, Tanabe H, Nishiyama T, Ito H, Amizuka N, Li M, Katsube KI, Kii I, Kudo A.  Periostin is required for matricellular localization of CCN3 in periodontal ligament of mice.  J Cell Commun Signal  2017  11:5-13  PubMed ID: 28013443
Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.  Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.  Sci Rep  2016  6:39557  PubMed ID: 28008968
Hirayama S, Hori Y, Benedek Z, Suzuki T, Kikuchi K.  Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking.  Nat. Chem. Biol.  2016  12:853-9  PubMed ID: 27547921
Hou S, Hang Q, Isaji T, Lu J, Fukuda T, Gu J.  Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation.  FASEB J.  2016  30:4120-4131  PubMed ID: 27565712
Matsui T, Hori A, Hamako J, Matsushita F, Ozeki Y, Sakurai Y, Hayakawa M, Matsumoto M, Fujimura Y.  Mutant botrocetin-2 inhibits von Willebrand factor-induced platelet agglutination.  J. Thromb. Haemost.  2017  15:538-548  PubMed ID: 28071872
Tsukamoto T, Chiba Y, Nakazaki A, Ishikawa Y, Nakane Y, Cho Y, Yotsu-Yamashita M, Nishikawa T, Wakamori M, Konoki K.  Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.  Bioorg. Med. Chem. Lett.  2017  27:1247-1251  PubMed ID: 28143690
Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K.  EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.  Neoplasia  2017  19:185-195  PubMed ID: 28152424
Hang Q, Isaji T, Hou S, Wang Y, Fukuda T, Gu J.  A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin α5 for Cell Migration.  Mol. Cell. Biol.  2017  37:  PubMed ID: 28167607
Kawaguchi Y, Nariki H, Kawamoto N, Kanehiro Y, Miyazaki S, Suzuki M, Magari M, Tokumitsu H, Kanayama N.  SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.  Biochem. Biophys. Res. Commun.  2017  485:261-266  PubMed ID: 28235482
Wada Y, Orba Y, Sasaki M, Kobayashi S, Carr MJ, Nobori H, Sato A, Hall WW, Sawa H.  Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.  Virology  2017  505:102-112  PubMed ID: 28236746
Yamagata K, Kobayashi A.  The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K36.  J. Biochem.  2017  161:327-330  PubMed ID: 28130413
Tatebe H, Murayama S, Yonekura T, Hatano T, Richter D, Furuya T, Kataoka S, Furuita K, Kojima C, Shiozaki K.  Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.  Elife  2017  6:  PubMed ID: 28264193
Hossain MS, Abe Y, Ali F, Youssef M, Honsho M, Fujiki Y, Katafuchi T.  Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-κB Signal Leading to Microglial Activation.  J. Neurosci.  2017  37:4074-4092  PubMed ID: 28292831
Guo L, Elcioglu NH, Mizumoto S, Wang Z, Noyan B, Albayrak HM, Yamada S, Matsumoto N, Miyake N, Nishimura G, Ikegawa S.  Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia.  J. Hum. Genet.  2017  62:797-801  PubMed ID: 28331220
Hashimoto H, Suda Y, Miyashita T, Ochiai A, Tsuboi M, Masutomi K, Kiyono T, Ishii G.  A novel method to generate single-cell-derived cancer-associated fibroblast clones.  J. Cancer Res. Clin. Oncol.  2017  143:1409-1419  PubMed ID: 28364361
Goyal S, Suzuki T, Li JR, Maeda S, Kishima M, Nishimura H, Shimizu Y, Suzuki H.  RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions.  BMC Mol. Biol.  2017  18:9  PubMed ID: 28376714
Hiwa R, Ohmura K, Arase N, Jin H, Hirayasu K, Kohyama M, Suenaga T, Saito F, Terao C, Atsumi T, Iwatani H, Mimori T, Arase H.  Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.    2017  69:2069-2080  PubMed ID: 28575531
Takahashi Y, Tanikawa C, Miyamoto T, Hirata M, Wang G, Ueda K, Komatsu T, Matsuda K.  Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.  Int. J. Oncol.  2017  51:724-736  PubMed ID: 28714518
Ishii T, Homma K, Mano A, Akagi T, Shigematsu Y, Shimoda Y, Inoue H, Kakinuma Y, Kaneda M.  Novel channel-mediated choline transport in cholinergic neurons of the mouse retina.  J. Neurophysiol.  2017  118:1952-1961  PubMed ID: 28701543
Morita K, Maeda S, Suzuki K, Kiyose H, Taniguchi J, Liu PP, Sugiyama H, Adachi S, Kamikubo Y.  Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions.  Blood Adv  2017  1:1440-1451  PubMed ID: 29296785
Oda K, Oda T, Matoba Y, Sato M, Irie T, Sakaguchi T.  Structural analysis of the STAT1:STAT2 heterodimer revealed the mechanism of Sendai virus C protein-mediated blockade of type 1 interferon signaling.  J. Biol. Chem.  2017  292:19752-19766  PubMed ID: 28978648
Hirano K, Namihira M.  FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.  FEBS Open Bio  2017  7:1932-1942  PubMed ID: 29226080
Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.  An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.  BMC Nephrol  2017  18:353  PubMed ID: 29202719
Suzuki T, Maeda S, Furuhata E, Shimizu Y, Nishimura H, Kishima M, Suzuki H.  A screening system to identify transcription factors that induce binding site-directed DNA demethylation.  Epigenetics Chromatin  2017  10:60  PubMed ID: 29221486
Koshizuka T, Kobayashi T, Ishioka K, Suzutani T.  Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.  Sci Rep  2018  8:4447  PubMed ID: 29535361
Mochimaru Y, Negishi J, Murakami S, Musha S, Sato K, Okajima F, Tomura H.  Metals Differentially Activate Ovarian Cancer G Protein-Coupled Receptor 1 in Various Species.  Zool. Sci.  2018  35:109-114  PubMed ID: 29623784
Yamashita W, Takahashi M, Kikkawa T, Gotoh H, Osumi N, Ono K, Nomura T.  Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain.  Development  2018  145:  PubMed ID: 29661783
Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Cherasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q.  Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.  Nat Commun  2018    PubMed ID: 29795268
Iuchi K, Morisada Y, Yoshino Y, Himuro T, Saito Y, Murakami T, Hisatomi H.  Cold atmospheric-pressure nitrogen plasma induces the production of reactive nitrogen species and cell death by increasing intracellular calcium in HEK293T cells.  Arch. Biochem. Biophys.  2018    PubMed ID: 30026027
Funakohi-Tago M, Sakata T, Fujiwara S, Sakakura A, Sugai T, Tago K, Tamura H.  Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells.  Eur. J. Pharmacol.  2018    PubMed ID: 30053409
Ali F, Hossain MS, Sejimo S, Akashi K.  Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.  Mol. Neurobiol.  2018    PubMed ID: 30128650
Kawaguchi M, Tani T, Hombu R, Ieda N, Nakagawa H.  Development and cellular application of visible-light-controllable HNO releasers based on caged Piloty's acid.  Chem. Commun. (Camb.)  2018    PubMed ID: 30152479
Shiozawa Y, Malcovati L, Galli A, Sato-Otsubo A, Kataoka K, Sato Y, Watatani Y, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Makishima H, Shiraishi Y, Chiba K, Hellstrom-Lindberg E, Miyano S, Ogawa S, Cazzola M.  Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.  Nat Commun  2018    PubMed ID: 30194306
Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.  UBL3 modification influences protein sorting to small extracellular vesicles.  Nat Commun  2018    PubMed ID: 30258067
Aoshima K, Fukui Y, Gulay KCM, Erdemsurakh O, Morita A, Kobayashi A, Kimura T.  Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells.  BMC Vet. Res.  2018    PubMed ID: 30285832
Ito S, Kayukawa N, Ueda T, Taniguchi H, Morioka Y, Hongo F, Ukimura O.  MRGBP promotes AR-mediated transactivation of KLK3 and TMPRSS2 via acetylation of histone H2A.Z in prostate cancer cells.  Biochim Biophys Acta Gene Regul Mech  2018    PubMed ID: 30076933
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Matsumoto N, Nakanishi-Matsui M.  Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30717974
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Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.  Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.  Sci Rep  2019    PubMed ID: 30837480
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Kandori S, Kojima T, Matsuoka T, Yoshino T, Sugiyama A, Nakamura E, Shimazui T, Funakoshi Y, Kanaho Y, Nishiyama H.  Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin.  Cancer Sci.  2018    PubMed ID: 29660846
Hirose Y, Onishi T, Miura S, Hatazawa Y, Kamei Y.  Vitamin D Attenuates FOXO1-Target Atrophy Gene Expression in C2C12 Muscle Cells.  J. Nutr. Sci. Vitaminol.  2018    PubMed ID: 29962435
Miyagawa Y, Matsushita Y, Suzuki H, Komatsu M, Yoshimaru T, Kimura R, Yanai A, Honda J, Tangoku A, Sasa M, Miyoshi Y, Katagiri T.  Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer.  Int. J. Oncol.  2018    PubMed ID: 29512727
Kumeta M, Panina Y, Yamazaki H, Takeyasu K, Yoshimura SH.  N-terminal dual lipidation-coupled molecular targeting into the primary cilium.  Genes Cells  2018    PubMed ID: 29900630
Kato Y, Ninomiya K, Ohashi K, Tomida S, Makimoto G, Watanabe H, Kudo K, Matsumoto S, Umemura S, Goto K, Ichihara E, Ninomiya T, Kubo T, Sato A, Hotta K, Tabata M, Toyooka S, Maeda Y, Kiura K.  Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.  Cancer Sci.  2018    PubMed ID: 30053332
Ito S, Ueno A, Ueda T, Nakagawa H, Taniguchi H, Kayukawa N, Fujihara-Iwata A, Hongo F, Okihara K, Ukimura O.  CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.  Oncotarget  2018    PubMed ID: 29707137
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