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RCB2100 : TE-11  update : 2018/08/02
CommentHuman cell line derived from esophageal cancer. Moderately differentiated squamous cell carcinoma. TKG0262 (Deposited from Tohoku Univ.).
Comment from the depositor
Terms and conditionsA prior written permission of the approver(Originator) is necessary for any kind of use including academic use and for-profit use.
Remarks
approver's address
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English
Address
Koseikai Hospital

320-1 Yamada, Kawagoe city, Saitama 350-8588, Japan
Dr.Nishihira, Tetsuro
Fax. +81-49-223-5713
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Obinata, Masuo
Originator Nishihira, Tetsuro
Year of deposit 2005
Original cell TKG0262
Animal human < Mammals
Genus Homo
Species sapiens
Age at sampling 58 years
Tissue esophagus
Case history Moderately differntiated squamous carcinoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0262)
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 0
User's Publication 24


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Reference

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User's Publication
7350  Interleukin-32 expression and Treg infiltration in esophageal squamous cell carcinoma.  Nabeki B, Ishigami S, Uchikado Y, Sasaki K, Kita Y, Okumura H, Arigami T, Kijima Y, Kurahara H, Maemura K, Natsugoe S.  Anticancer Res.  2015  35:2941-7  PubMed ID: 25964580
7382  The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.  Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor AK, Yasuda Y, Niki T.  BMC Cancer  2015  15:82  PubMed ID: 25884729
9599  Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma.  Kikuchi O, Ohashi S, Horibe T, Kohno M, Nakai Y, Miyamoto S, Chiba T, Muto M, Kawakami K.  Sci Rep  2016  6:22452  PubMed ID: 26956916
9656  Downregulation of SIRT4 Expression Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma.  Nakahara Y, Yamasaki M, Sawada G, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mimori K, Mori M, Doki Y.  Oncology  2016  90:347-55  PubMed ID: 27082627
9724  Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma.  Hara H, Takahashi T, Serada S, Fujimoto M, Ohkawara T, Nakatsuka R, Harada E, Nishigaki T, Takahashi Y, Nojima S, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Miyata H, Nakajima K, Takiguchi S, Morii E, Mori M, Doki Y, Naka T.  Br. J. Cancer  2016  115:66-75  PubMed ID: 27310703
10141  Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice.  Sugase T, Takahashi T, Serada S, Nakatsuka R, Fujimoto M, Ohkawara T, Hara H, Nishigaki T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Kishimoto T, Mori M, Doki Y, Naka T.  Int. J. Cancer  2017  140:2608-2621  PubMed ID: 28233302
10353  Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.  Kawaguchi T, Komatsu S, Ichikawa D, Hirajima S, Nishimura Y, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.  Tumour Biol.  2017  39:1010428317700409  PubMed ID: 28618928
10365  Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma.  Yamamoto M, Yamasaki M, Tsukao Y, Tanaka K, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.  Oncol Lett  2017  14:1581-1587  PubMed ID: 28789382
10449  Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.  Yoshioka M, Ohashi S, Ida T, Nakai Y, Kikuchi O, Amanuma Y, Matsubara J, Yamada A, Miyamoto S, Natsuizaka M, Nakagawa H, Chiba T, Seno H, Muto M.  J. Exp. Clin. Cancer Res.  2017  36:101  PubMed ID: 28764725
10555  High Expression of the Mitophagy-Related Protein Pink1 is Associated with a Poor Response to Chemotherapy and a Poor Prognosis for Patients Treated with Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma.  Yamashita K, Miyata H, Makino T, Masuike Y, Furukawa H, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Morii E, Mori M, Doki Y.  Ann. Surg. Oncol.  2017  24:4025-4032  PubMed ID: 29022200
10718  Drug repurposing screening identifies bortezomib and panobinostat as drugs targeting cancer associated fibroblasts (CAFs) by synergistic induction of apoptosis.  Lee HM, Lee E, Yeo SY, Shin S, Park HK, Nam DH, Kim SH.  Invest New Drugs  2018  36(4):545-560  PubMed ID: 29349597
10755  Esophageal squamous cell carcinoma with low mitochondrial copy number has mesenchymal and stem-like characteristics, and contributes to poor prognosis.  Masuike Y, Tanaka K, Makino T, Yamasaki M, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Mori M, Doki Y.  PLoS ONE  2018  13:e0193159  PubMed ID: 29447301
10798  Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.  Shinno N, Kimura H, Sada R, Takiguchi S, Mori M, Fumoto K, Doki Y, Kikuchi A.  Oncogene  2018  37(26):3471-3484  PubMed ID: 29563607
10977  Role of HDM2 Gene in Radio-Sensitivity of Esophageal Cancer Cell Lines to Irradiation    Int J Cancer Manag  2017  10:e8950 
11491  Induction of Apoptosis by a Combination of 2-Deoxyglucose and Metformin in Esophageal Squamous Cell Carcinoma by Targeting Cancer Cell Metabolism.  Shafaee A, Pirayesh Islamian J, Zarei D, Mohammadi M, Nejati-Koshki K, Farajollahi A, Aghamiri SMR, Rahmati Yamchi M, Baradaran B, Asghari Jafarabadi M.  Iran J Med Sci  2019    PubMed ID: 30936596
4355  PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.  Furukawa H, Makino T, Yamasaki M, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.  Cancer Sci.  2018  109(2):412-421  PubMed ID: 29168598
4357  Oncogenic IL7R is downregulated by histone deacetylase inhibitor in esophageal squamous cell carcinoma via modulation of acetylated FOXO1.  Kim MJ, Choi SK, Hong SH, Eun JW, Nam SW, Han JW, You JS.  Int. J. Oncol.  2018  53(1):395-403  PubMed ID: 29749437
4504  B7H4 is associated with stemness and cancer progression in esophageal squamous cell carcinoma.  Piao L, Yang Z, Jin J, Ni W, Qi W, Xuan Y.  Hum. Pathol.  2018  80:152-162  PubMed ID: 29885401
4505  Identification of LETM1 as a marker of cancer stem-like cells and predictor of poor prognosis in esophageal squamous cell carcinoma.  Yang Z, Ni W, Cui C, Qi W, Piao L, Xuan Y.  Hum. Pathol.  2018  81:148-156  PubMed ID: 30031102
4386  Stromal fibroblasts are predictors of disease-related mortality in esophageal squamous cell carcinoma.  Saito S, Morishima K, Ui T, Matsubara D, Tamura T, Oguni S, Hosoya Y, Sata N, Lefor AT, Yasuda Y, Niki T  Oncol Rep  2014  32(1):348-54  PubMed ID: 24859885
11583  PI3Kα inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment.  Shi JJ, Xing H, Wang YX, Zhang X, Zhan QM, Geng MY, Ding J, Meng LH.  Cancer Lett.  2019    PubMed ID: 31173854
11598  The clinical impact of angiotensin-(1-7)/mitochondrial assembly receptor axis in esophageal squamous cell carcinoma patients receiving curative esophagectomy.  Chen YH, Lu HI, Lo CM, Huang CC, Hsiao CC, Li SH.  J. Formos. Med. Assoc.  2019    PubMed ID: 31202501
11791  Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF.  Shin WS, Lee HW, Lee ST.  FASEB J.  2019    PubMed ID: 31490704
6410  Is parainfluenza virus a threatening virus for human cancer cell lines?  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309



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