| 利用者成果(英) |
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21175
Zhang X, Wang Y, Zhang X, Shen Y, Yang K, Ma Q, Qiao Y, Shi J, Wang Y, Xu L, Yang B, Ge G, Hu L, Kong X, Yang C, Chen Y, Ding J, Meng L.
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors.
Signal Transduct Target Ther
2023
8(1):153
PubMed ID: 37041169
DOI: 10.1038/s41392-023-01359-x
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16142
Dong X, Chen X, Lu D, Diao D, Liu X, Mai S, Feng S, Xiong G.
LncRNA miR205HG hinders HNRNPA0 translation: anti-oncogenic effects in esophageal carcinoma
Mol Oncol
2022
16(3):795-812
PubMed ID: 34821009
DOI: 10.1002/1878-0261.13142
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20614
Tsuchihashi K, Hirata Y, Yamasaki J, Suina K, Tanoue K, Yae T, Masuda K, Baba E, Akashi K, Kitagawa Y, Saya H, Nagano O.
Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer.
Biochem Biophys Rep
2022
30:101246
PubMed ID: 35330672
DOI: 10.1016/j.bbrep.2022.101246
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20682
Masuda T, Tazawa H, Hashimoto Y, Ieda T, Kikuchi S, Kuroda S, Noma K, Urata Y, Kagawa S, Fujiwara T.
Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells.
Acta Med Okayama
2022
76(2):203-215
PubMed ID: 35503449
DOI: 10.18926/AMO/63425
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16116
Kobayashi T, Makino T, Yamashita K, Saito T, Tanaka K, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Morii E, Eguchi H, Doki Y.
APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutation
Br J Cancer
2021
125(11):1523-1532
PubMed ID: 34599296
DOI: 10.1038/s41416-021-01561-0
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6883
Terayama M, Yamada K, Hagiwara T, Inazuka F, Sezaki T, Igari T, Yokoi C, Nohara K, Soma D, Dohi T, Kawamura Y.
Glutathione S-transferase omega 2 regulates cell growth and the expression of E-cadherin via post-transcriptional downregulation of β-catenin in human esophageal squamous cells.
Carcinogenesis
2020
41(7):875-886
PubMed ID: 31738399
DOI: 10.1093/carcin/bgz189
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13600
Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.
p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers
Biochem Biophys Res Commun
2020
529(3):582-589.
PubMed ID: 32736677
DOI: 10.1016/j.bbrc.2020.05.168
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11511
Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature
2019
PubMed ID: 30971826
DOI: 10.1038/s41586-019-1103-9
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11631
Konishi T, Shiozaki A, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Otsuji E.
LRRC8A Expression Influences Growth of Esophageal Squamous Cell Carcinoma.
Am. J. Pathol.
2019
PubMed ID: 31323188
DOI: 10.1016/j.ajpath.2019.06.006
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11699
Kiyozumi Y, Baba Y, Okadome K, Yagi T, Ogata Y, Eto K, Hiyoshi Y, Ishimoto T, Iwatsuki M, Iwagami S, Miyamoto Y, Yoshida N, Watanabe M, Baba H.
Indoleamine 2, 3-dioxygenase 1 promoter hypomethylation is associated with poor prognosis in patients with esophageal cancer.
Cancer Sci
2019
110(6):1863-1871
PubMed ID: 31012515
DOI: 10.1111/cas.14028
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12594
Kalikawe R, Baba Y, Nomoto D, Okadome K, Miyake K, Eto K, Hiyoshi Y, Nagai Y, Iwatsuki M, Ishimoto T, Iwagami S, Miyamoto Y, Yoshida N, Watanabe M, Baba H.
Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer
Cancer Sci
2019
110(12):3727-3737
PubMed ID: 31599475
DOI: 10.1111/cas.14214
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12595
Sawayama H, Ogata Y, Ishimoto T, Mima K, Hiyoshi Y, Iwatsuki M, Baba Y, Miyamoto Y, Yoshida N, Baba H.
Glucose transporter 1 regulates the proliferation and cisplatin sensitivity of esophageal cancer
Cancer Sci
2019
110(5):1705-1714
PubMed ID: 30861255
DOI: 10.1111/cas.13995
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10798
Shinno N, Kimura H, Sada R, Takiguchi S, Mori M, Fumoto K, Doki Y, Kikuchi A.
Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.
Oncogene
2018
37(26):3471-3484
PubMed ID: 29563607
DOI: 10.1038/s41388-018-0179-2
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11088
Thomenius MJ, Totman J, Harvey D, Mitchell LH, Riera TV, Cosmopoulos K, Grassian AR, Klaus C, Foley M, Admirand EA, Jahic H, Majer C, Wigle T, Jacques SL, Gureasko J, Brach D, Lingaraj T, West K, Smith S, Rioux N, Waters NJ, Tang C, Raimondi A, Munchhof M, Mills JE, Ribich S, Porter Scott M, Kuntz KW, Janzen WP, Moyer M, Smith JJ, Chesworth R, Copeland RA, Boriack-Sjodin PA.
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
PLoS ONE
2018
13(6):e0197372
PubMed ID: 29856759
DOI: 10.1371/journal.pone.0197372
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4355
Furukawa H, Makino T, Yamasaki M, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.
PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.
Cancer Sci.
2018
109(2):412-421
PubMed ID: 29168598
DOI: 10.1111/cas.13454
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9448
Chihiro Kajiwara, Katsumi Fumoto, Hirokazu Kimura, Satoshi Nojima, Keita Asano, Kazuki Odagiri, Makoto Yamasaki, Hayato Hikita, Tetsuo Takehara, Yuichiro Doki, Eiichi Morii, Akira Kikuchii
p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Cancer Res
2018
78(21):6107-6120
PubMed ID: 30181180
DOI: 10.1158/0008-5472.CAN-18-1749
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13126
Gaowa S, Futamura M, Tsuneki M, Kamino H, Tajima JY, Mori R, Arakawa H, Yoshida K.
Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Cancer Sci
2018
PubMed ID: 30290054
DOI: 10.1111/cas.13824
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14921
Lee TS, Song IH, Shin JI, Park YS, Kim JY, Kim KI, Lee YJ, Kang JH.
PET Imaging Biomarkers of Anti-EGFR Immunotherapy in Esophageal Squamous Cell Carcinoma Models
Cells
2018
7(11):187
PubMed ID: 30373221
DOI: 10.3390/cells7110187
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10141
Sugase T, Takahashi T, Serada S, Nakatsuka R, Fujimoto M, Ohkawara T, Hara H, Nishigaki T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Kishimoto T, Mori M, Doki Y, Naka T.
Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice.
Int. J. Cancer
2017
140:2608-2621
PubMed ID: 28233302
DOI: 10.1002/ijc.30666
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10353
Kawaguchi T, Komatsu S, Ichikawa D, Hirajima S, Nishimura Y, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.
Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.
Tumour Biol.
2017
39:1010428317700409
PubMed ID: 28618928
DOI: 10.1177/1010428317700409
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10365
Yamamoto M, Yamasaki M, Tsukao Y, Tanaka K, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.
Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma.
Oncol Lett
2017
14:1581-1587
PubMed ID: 28789382
DOI: 10.3892/ol.2017.6334
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14217
Sugase T, Takahashi T, Serada S, Fujimoto M, Hiramatsu K, Ohkawara T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Kishimoto T, Mori M, Doki Y, Naka T.
SOCS1 Gene Therapy Improves Radiosensitivity and Enhances Irradiation-Induced DNA Damage in Esophageal Squamous Cell Carcinoma
Cancer Res
2017
77(24):6975-6986
PubMed ID: 29042418
DOI: 10.1158/0008-5472.CAN-17-1525
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14559
Sci Rep
MiR-338-5p enhances the radiosensitivity of esophageal squamous cell carcinoma by inducing apoptosis through targeting survivin
2017
7(1):10932
PubMed ID: 28883406
DOI: 10.1038/s41598-017-10977-9
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9656
Nakahara Y, Yamasaki M, Sawada G, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mimori K, Mori M, Doki Y.
Downregulation of SIRT4 Expression Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma.
Oncology
2016
90:347-55
PubMed ID: 27082627
DOI: 10.1159/000445323
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12618
Kosumi K, Baba Y, Sakamoto A, Ishimoto T, Harada K, Nakamura K, Kurashige J, Hiyoshi Y, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Hino S, Nakao M, Baba H.
Lysine-specific demethylase-1 contributes to malignant behavior by regulation of invasive activity and metabolic shift in esophageal cancer
Int J Cancer
2016
138(2):428-39
PubMed ID: 26240060
DOI: 10.1002/ijc.29714
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12663
Song IH, Lee TS, Park YS, Lee JS, Lee BC, Moon BS, An GI, Lee HW, Kim KI, Lee YJ, Kang JH, Lim SM.
Immuno-PET Imaging and Radioimmunotherapy of 64Cu-/177Lu-Labeled Anti-EGFR Antibody in Esophageal Squamous Cell Carcinoma Model
J Nucl Med
2016
57(7):1105-11
PubMed ID: 26917708
DOI: 10.2967/jnumed.115.167155
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12969
Hamada J, Shoda K, Masuda K, Fujita Y, Naruto T, Kohmoto T, Miyakami Y, Watanabe M, Kudo Y, Fujiwara H, Ichikawa D, Otsuji E, Imoto I.
Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma
Oncotarget
2016
7(13):17111-28
PubMed ID: 26958940
DOI: 10.18632/oncotarget.7937
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13992
Nakamura K, Baba Y, Kosumi K, Harada K, Shigaki H, Miyake K, Kiyozumi Y, Ohuchi M, Kurashige J, Ishimoto T, Iwatsuki M, Sakamoto Y, Yoshida N, Watanabe M, Nakao M, Baba H.
UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma
Oncotarget
2016
7(36):57821-5783
PubMed ID: 27507047
DOI: 10.18632/oncotarget.11067
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14119
Park M, Yoon HJ, Kang MC, Kwon J, Lee HW.
PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma
Tumour Biol
2016
37(10):14217-14224
PubMed ID: 27557627
DOI: 10.1007/s13277-016-5288-3
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7382
Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor AK, Yasuda Y, Niki T.
The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.
BMC Cancer
2015
15:82
PubMed ID: 25884729
DOI: 10.1186/s12885-015-1065-8
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15184
Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Oki E, Watanabe M, Baba H.
Suppressor microRNA-145 Is Epigenetically Regulated by Promoter Hypermethylation in Esophageal Squamous Cell Carcinom
Anticancer Res
2015
35(9):4617-24
PubMed ID: 26254350
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15448
Fujii S, Fujihara A, Natori K, Abe A, Kuboki Y, Higuchi Y, Aizawa M, Kuwata T, Kinoshita T, Yasui W, Ochiai A.
TEM1 expression in cancer-associated fibroblasts is correlated with a poor prognosis in patients with gastric cancer
Cancer Med
2015
4(11):1667-78
PubMed ID: 26336878
DOI: 10.1002/cam4.515
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5608
Zhou X, Koizumi Y, Zhang M, Natsui M, Koyota S, Yamada M, Kondo Y, Hamada F, Sugiyama T.
Cadmium-coordinated supramolecule suppresses tumor growth of T-cell leukemia in mice
Cancer Sci
2015
106(5):635-41
PubMed ID: 25735932
DOI: 10.1111/cas.12651
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13765
Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Sugihara H, Kurashige J, Hirashima K, Iwatsuki M, Baba Y, Oki E, Morita M, Shiose Y, Baba H.
Small molecule agonists of PPAR-γ exert therapeutic effects in esophageal cancer
Cancer Res
2014
74(2):575-85
PubMed ID: 24272485
DOI: 10.1158/0008-5472.CAN-13-1836
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15825
Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment
Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment
Cancer Sci
2014
105(10):1236-44
PubMed ID: 25154680
DOI: 10.1111/cas.12503
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16011
Zhang S, Tang W, Weng S, Liu X, Rao B, Gu J, Chen S, Wang Q, Shen X, Xue R, Dong L.
Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma
Oncotarget
2014
5(16):7183-97
PubMed ID: 25216531
DOI: 10.18632/oncotarget.2293
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17149
Yeo SY, Ha SY, Yu EJ, Lee KW, Kim JH, Kim SH.
ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, pr
Oncotarget
2014
5(23):12260-72
PubMed ID: 25373738
DOI: 10.18632/oncotarget.2630
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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