Search
CELL BANK Website

Back Back
RCB1972 : PK-1  update : 2018/08/02
CommentHuman pancreatic carcinoma cell line. RCB2138 was derived from the same patient. TKG0239 (Deposited from Tohoku Univ.).
Comment from the depositor
Restriction (Category)a
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Obinata, Masuo
Originator Kobari, M.
Year of deposit 2004
Original cell TKG0239
Animal human < Mammals
Genus Homo
Species sapiens
Tissue pancreas
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0239)
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 3
User's Publication 10


To topTop
Reference
Kobari M, Matsuno S, Sato T, Kan M, Tachibana T  Establishment of a human pancreatic cancer cell line and detection of pancreatic cancer associated antigen.  Tohoku J Exp Med  1984  143:33-46 
Yamada T, Okajima F, Ohwada S, Kondo Y  Growth inhibition of human pancreatic cancer cells by sphingosylphosphorylcholine and influence of culture conditions.  Cell Mol Life Sci  1997  53:435-41 
Shibata K, Mori M, Tanaka S, Kitano S, Akiyoshi T  Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer.  Biochem Biophys Res Commun  1998  246:205-9 

To topTop
User's Publication
Kanno, Syu-Ichi, Tomizawa, Ayako, Hiura, Takako, Osanai, Yuu, Shouji, Ai, Ujibe, Mayuko, Ohtake, Takaharu, Kimura, Katsuhiko, Ishikawa, Masaaki  Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice.  Biol Pharm Bull  2005  28:527-30  PubMed ID: 15744083
Miyamae M, Komatsu S, Ichikawa D, Kawaguchi T, Hirajima S, Okajima W, Ohashi T, Imamura T, Konishi H, Shiozaki A, Morimura R, Ikoma H, Ochiai T, Okamoto K, Taniguchi H, Otsuji E.  Plasma microRNA profiles: identification of miR-744 as a novel diagnostic and prognostic biomarker in pancreatic cancer.  Br. J. Cancer  2015  113:1467-76  PubMed ID: 26505678
Namba T, Kodama R, Moritomo S, Hoshino T, Mizushima T.  Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3β-Snail pathway.  Cell Death Dis  2015  6:e1795  PubMed ID: 26111057
Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S.  Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer.  Cancer Res.  2015  75:2629-40  PubMed ID: 25952647
Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.  Insulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer.  World J. Gastroenterol.  2010  16:1854-8  PubMed ID: 20397262
Suzuki J, Murakami Y, Samejima K, Ohtani KK, Oka T.  Antizyme is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells.  Endocr. Relat. Cancer  2009  16:649-59  PubMed ID: 19349429
Hijiya N, Tsukamoto Y, Nakada C, Tung Nguyen L, Kai T, Matsuura K, Shibata K, Inomata M, Uchida T, Tokunaga A, Amada K, Shirao K, Yamada Y, Mori H, Takeuchi I, Seto M, Aoki M, Takekawa M, Moriyama M.  Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma.  Cancer Res.  2016  76:2612-25  PubMed ID: 26941286
Ellebaek S, Brix S, Grandal M, Lantto J, Horak ID, Kragh M, Poulsen TT.  Pan-HER-An antibody mixture targeting EGFR, HER2 and HER3 abrogates preformed and ligand-induced EGFR homo- and heterodimers.  Int. J. Cancer  2016  139:2095-105  PubMed ID: 27342948
Machihara K, Tanaka H, Hayashi Y, Murakami I, Namba T.  Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78.  Biochem. Biophys. Res. Commun.  2017  492:33-40  PubMed ID: 28811106
Okura R, Fujihara S, Iwama H, Morishita A, Chiyo T, Watanabe M, Hirose K, Kobayashi K, Fujimori T, Kato K, Kamada H, Kobara H, Mori H, Niki T, Hirashima M, Okano K, Suzuki Y, Masaki T.  MicroRNA profiles during galectin-9-induced apoptosis of pancreatic cancer cells.  Oncol Lett  2018  15:407-414  PubMed ID: 29387226



Back Back Return Top Page