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RCB1951 : TE-15  update : 2018/08/01
CommentHuman cell line derived from esophageal cancer (highly differentiated squamous cell carcinoma). Not transplantable to nude mouse. TKG0266 (Deposited from Tohoku Univ.).
Comment from the depositor
Use conditionc
Use condition descriptionA prior written permission of the approver(Originator) is necessary for any kind of use including academic use and for-profit use.
approver's address
×
English
Address
Koseikai Hospital

320-1 Yamada, Kawagoe city, Saitama 350-8588 Japan
Dr.Nishihira, Tetsuro
Fax. +81-49-223-5713
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Obinata, Masuo
Originator Nishihira, Tetsuro (Akaishi, T.)
Year of deposit 2004
Original cell TKG0266
Animal human < Mammals
Genus Homo
Species sapiens
Gender Female
Tissue esophagus
Case history squamous carcinoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0266)
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Coating dish type I collagen coated dish
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 2
User's Publication 6


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Reference
Hay, Park, Gazdar, Ed.    Atlas of Human Tumor Cell Lines  1994  269-282 
Nishihira T, Hashimoto Y, Katayama M, Mori S, Kuroki T  Molecular and cellular features of esophageal cancer cells.  J Cancer Res Clin Oncol  1993  119:441-9 

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User's Publication
Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor AK, Yasuda Y, Niki T.  The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.  BMC Cancer  2015  15:82  PubMed ID: 25884729
Ooki A, Yamashita K, Kikuchi S, Sakuramoto S, Katada N, Watanabe M.  Phosphatase of regenerating liver-3 as a convergent therapeutic target for lymph node metastasis in esophageal squamous cell carcinoma.  Int. J. Cancer  2009  127:543-54  PubMed ID: 19960436
Hara H, Takahashi T, Serada S, Fujimoto M, Ohkawara T, Nakatsuka R, Harada E, Nishigaki T, Takahashi Y, Nojima S, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Miyata H, Nakajima K, Takiguchi S, Morii E, Mori M, Doki Y, Naka T.  Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma.  Br. J. Cancer  2016  115:66-75  PubMed ID: 27310703
Sugase T, Takahashi T, Serada S, Nakatsuka R, Fujimoto M, Ohkawara T, Hara H, Nishigaki T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Kishimoto T, Mori M, Doki Y, Naka T.  Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice.  Int. J. Cancer  2017  140:2608-2621  PubMed ID: 28233302
Kawaguchi T, Komatsu S, Ichikawa D, Hirajima S, Nishimura Y, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.  Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.  Tumour Biol.  2017  39:1010428317700409  PubMed ID: 28618928
Hosono M, Koma YI, Takase N, Urakawa N, Higashino N, Suemune K, Kodaira H, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H.  CXCL8 derived from tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression by promoting migration and invasion of cancer cells.  Oncotarget  2017  8:106071-106088  PubMed ID: 29285315



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