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RCB1886 : Hep G2  update : 2018/08/01
CommentHuman cell line derived from hepatocyte carcinoma. TKG0205 (Deposited from Tohoku Univ.). Information
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Obinata, Masuo
Year of deposit 2004
Original cell TKG0205 HepG2
Animal human < Mammals
Genus Homo
Species sapiens
Race Caucasian
Gender Male
Age at sampling 15 years
Tissue liver
Case history hepatocyte carcinoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0205)
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM (low glucose) + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Virus (HBV) (-)
Virus (HCV) (-)
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 3
User's Publication 76


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Reference
465  Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line.  Aden, D P, Fogel A, Plotkin S, Damjanov I, Knowles, B B  Nature  1979  282:615-6  PubMed ID: 233137
1155  Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen.  Knowles, B B, Howe, C C, Aden, D P  Science  1980  209:497-9  PubMed ID: 6248960
4984  Metabolic activation of benzo[a]pyrene by a human hepatoma cell line.  Diamond L1, Kruszewski F, Aden DP, Knowles BB, Baird WM.  Carcinogenesis  1980  1(10):871-5  PubMed ID: 11219860

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User's Publication
7067  Fluorescence probes to detect lipid-derived radicals.  Yamada K, Mito F, Matsuoka Y, Ide S, Shikimachi K, Fujiki A, Kusakabe D, Ishida Y, Enoki M, Tada A, Ariyoshi M, Yamasaki T, Yamato M.  Nat. Chem. Biol.  2016  12:608-13  PubMed ID: 27294322
7092  Production of hyaluronic-acid-based cell-enclosing microparticles and microcapsules via enzymatic reaction using a microfluidic system.  M Khanmohammadi, S Sakai, T Ashida, M Taya  J Applied Polymer Science  2016  133:43107 
7125  Constitutive Effects of Lead on Aryl Hydrocarbon Receptor Gene Battery and Protection by β-carotene and Ascorbic Acid in Human HepG2 Cells.  Darwish WS, Ikenaka Y, Nakayama SM, Mizukawa H, Ishizuka M.  J. Food Sci.  2015  81:T275-81  PubMed ID: 26630500
7128  Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines.  Sato Y, Sasaki T, Takahashi S, Kumagai T, Nagata K.  J Pharm Pharm Sci  2015  18:316-27  PubMed ID: 26626238
7153  Effects of scorched food leachates with or without activated charcoal pretreatment on AhR activation in cultured cells.  Takahashi S, Morita K, Kinoshita M, Fujimori S, Ishikawa T.  J Toxicol Sci  2015  40:777-86  PubMed ID: 26558458
7219  In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice.  Yamaza T, Alatas FS, Yuniartha R, Yamaza H, Fujiyoshi JK, Yanagi Y, Yoshimaru K, Hayashida M, Matsuura T, Aijima R, Ihara K, Ohga S, Shi S, Nonaka K, Taguchi T.  Stem Cell Res Ther  2015  6:171  PubMed ID: 26358689
7238  Abnormal Localization of STK17A in Bile Canaliculi in Liver Allografts: An Early Sign of Chronic Rejection.  Ozeki M, Salah A, Aini W, Tamaki K, Haga H, Miyagawa-Hayashino A.  PLoS ONE  2015  10:e0136381  PubMed ID: 26305096
7257  Detoxification of selenite to form selenocyanate in mammalian cells.  Anan Y, Kimura M, Hayashi M, Koike R, Ogra Y.  Chem. Res. Toxicol.  2015  28:1803-14  PubMed ID: 26243445
7270  Vascular-like network prepared using hollow hydrogel microfibers.  Takei T, Kitazono Z, Ozuno Y, Yoshinaga T, Nishimata H, Yoshida M.  J. Biosci. Bioeng.  2015  121:336-40  PubMed ID: 26199226
7278  Cannabidiol induces expression of human cytochrome P450 1A1 that is possibly mediated through aryl hydrocarbon receptor signaling in HepG2 cells.  Yamaori S, Kinugasa Y, Jiang R, Takeda S, Yamamoto I, Watanabe K.  Life Sci.  2015  136:87-93  PubMed ID: 26187180
7324  One-step scalable preparation method for non-cationic liposomes with high siRNA content.  Somiya M, Yamaguchi K, Liu Q, Niimi T, Maturana AD, Iijima M, Yoshimoto N, Kuroda S.  Int J Pharm  2015  490:316-23  PubMed ID: 26027493
7373  Fabrication of uniformly cell-laden porous scaffolds using a gas-in-liquid templating technique.  Takei T, Aokawa R, Shigemitsu T, Kawakami K, Yoshida M.  J. Biosci. Bioeng.  2015  120:577-81  PubMed ID: 25912452
7474  Metabolism and cytotoxic effects of phosphatidylcholine hydroperoxide in human hepatoma HepG2 cells.  Suzuki Y, Nakagawa K, Kato S, Tatewaki N, Mizuochi S, Ito J, Eitsuka T, Nishida H, Miyazawa T.  Biochem. Biophys. Res. Commun.  2015  458:920-7  PubMed ID: 25704087
7476  Generation and In Vitro Expansion of Hepatic Progenitor Cells from Human iPS Cells.  Yanagida A, Nakauchi H, Kamiya A.  Methods Mol. Biol.  2015  1357:295-310  PubMed ID: 25697415
7553  Natural geochemical risk in the Pollino Massif: a case-study of chromium.  Priscilla Boccia, Claudia Meconi, Elena Sturchio, Salvatore Margiotta, Pietro Ragone, Vito Summa  Frontiers in Genetics  2015  6: 
7568  Chemical Constituents from the Aerial Parts of Bupleurum falcatum L. and Biological Evidences.  Tung NH, Uto T, Morinaga O, Shoyama Y  Natural Product Sciences  2015  21:71-75 
9536  Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor.  Kumagai T, Aratsu Y, Sugawara R, Sasaki T, Miyairi S, Nagata K.  Drug Metab. Pharmacokinet.  2016  31:139-45  PubMed ID: 26987505
9555  Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells.  Watanabe S, Moniaga CS, Nielsen S, Hara-Chikuma M.  Biochem. Biophys. Res. Commun.  2016  471:191-7  PubMed ID: 26837049
9642  Effects of Hepatoprotective Compounds from the Leaves of Lumnitzera racemosa on Acetaminophen-Induced Liver Damage in Vitro.  Darwish AG, Samy MN, Sugimoto S, Otsuka H, Abdel-Salam H, Matsunami K.  Chem. Pharm. Bull.  2016  64:360-5  PubMed ID: 27039833
9701  Lipid droplets affect elimination of Porphyromonas gingivalis in HepG2 cells by altering the autophagy-lysosome system.  Zaitsu Y, Iwatake M, Sato K, Tsukuba T.  Microbes Infect.  2016  18:565-71  PubMed ID: 27237960
9717  Tetrandrine induces lipid accumulation through blockade of autophagy in a hepatic stellate cell line.  Miyamae Y, Nishito Y, Nakai N, Nagumo Y, Usui T, Masuda S, Kambe T, Nagao M.  Biochem. Biophys. Res. Commun.  2016  477:40-6  PubMed ID: 27270032
9775  Enzymatically-gellable galactosylated chitosan: Hydrogel characteristics and hepatic cell behavior.  Khoshfetrat AB, Khanmohammadi M, Sakai S, Taya M.  Int. J. Biol. Macromol.  2016  92:892-899  PubMed ID: 27496605
9812  Molecular hydrogen suppresses activated Wnt/β-catenin signaling.  Lin Y, Ohkawara B, Ito M, Misawa N, Miyamoto K, Takegami Y, Masuda A, Toyokuni S, Ohno K.  Sci Rep  2016  6:31986  PubMed ID: 27558955
9841  δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling.  Burdeos GC, Ito J, Eitsuka T, Nakagawa K, Kimura F, Miyazawa T.  Food Funct  2016  7:4170-4174  PubMed ID: 27713963
9946  Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator.  Abiko Y, Lin FY, Lee H, Puga A, Kumagai Y.  J Toxicol Sci  2016  41:775-781  PubMed ID: 27853106
9988  Purification, antitumor and immunomodulatory activity of polysaccharides from soybean residue fermented with Morchella esculenta.  Li S, Gao A, Dong S, Chen Y, Sun S, Lei Z, Zhang Z.  Int. J. Biol. Macromol.  2017  96:26-34  PubMed ID: 27939510
9990  Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression.  Tanaka Y, Tateishi K, Nakatsuka T, Kudo Y, Takahashi R, Miyabayashi K, Yamamoto K, Asaoka Y, Ijichi H, Tateishi R, Shibahara J, Fukayama M, Ishizawa T, Hasegawa K, Kokudo N, Koike K.  Oncogenesis  2016  5:e277  PubMed ID: 27941932
9996  ACE in three tunicae of rat aorta: expression in smooth muscle and effect of renovascular hypertension.  Arnal JF, Battle T, Rasetti C, Challah M, Costerousse O, Vicaut E, Michel JB, Alhenc-Gelas F.  Am. J. Physiol.  1994  267:H1777-84  PubMed ID: 7977808
10002  Cell death in a co-culture of hepatocellular carcinoma cells and human umbilical vascular endothelial cells in a medium lacking glucose and arginine.  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Oncol Lett  2017  13:258-262  PubMed ID: 28123551
10080  Correlation between luminescence intensity and cytotoxicity in cell-based cytotoxicity assay using luciferase.  Wakuri S, Yamakage K, Kazuki Y, Kazuki K, Oshimura M, Aburatani S, Yasunaga M, Nakajima Y.  Anal. Biochem.  2017  522:18-29  PubMed ID: 28111305
10167  Bioavailability Comparison of Nine Bioselenocompounds In Vitro and In Vivo.  Takahashi K, Suzuki N, Ogra Y.  Int J Mol Sci  2017  18:  PubMed ID: 28245633
10236  Human-derived fusogenic peptides for the intracellular delivery of proteins.  Sudo K, Niikura K, Iwaki K, Kohyama S, Fujiwara K, Doi N.  J Control Release  2017  255:1-11  PubMed ID: 28385674
10351  Gerontoxanthone B from Maclura cochinchinensis var. gerontogea exhibits anti-inflammatory potential as an aryl hydrocarbon receptor agonist.  Nakashima KI, Ogiwara T, Hirai T, Tanaka T, Murata H, Kaburagi K, Fujii-Kuriyama Y, Hayashi H, Inoue M.  Bioorg. Med. Chem.  2017  25:4253-4258  PubMed ID: 28662965
10392  Mechanisms of chromosomal aberrations induced by sesamin metabolites in Chinese hamster lung cells.  Ono Y, Tomimori N, Hori H, Kitagawa Y, Shibata H.  Mutat. Res.  2017  822:19-26  PubMed ID: 28844238
10435  Quassinoids from the Root of Eurycoma longifolia and Their Antiproliferative Activity on Human Cancer Cell Lines.  Tung NH, Uto T, Hai NT, Li G, Shoyama Y.  Pharmacogn Mag  2017  13:459-462  PubMed ID: 28839372
10446  Profiling of cardiolipins and their hydroperoxides in HepG2 cells by LC/MS.  Chen Z, Wu Y, Ma YS, Kobayashi Y, Zhao YY, Miura Y, Chiba H, Hui SP.  Anal Bioanal Chem  2017  409:5735-5745  PubMed ID: 28762068
10466  Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78.  Machihara K, Tanaka H, Hayashi Y, Murakami I, Namba T.  Biochem. Biophys. Res. Commun.  2017  492:33-40  PubMed ID: 28811106
10470  Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition.  Xu Z, Huo J, Ding X, Yang M, Li L, Dai J, Hosoe K, Kubo H, Mori M, Higuchi K, Sawashita J.  Sci Rep  2017  7:8253  PubMed ID: 28811612
10478  Multiple-endpoints gene alteration-based (MEGA) assay: A toxicogenomics approach for water quality assessment of wastewater effluents.  Fukushima T, Hara-Yamamura H, Nakashima K, Tan LC, Okabe S.  Chemosphere  2017  188:312-319  PubMed ID: 28888119
10488  Caffeine Has a Synergistic Anticancer Effect with Cisplatin via Inhibiting Fanconi Anemia Group D2 Protein Monoubiquitination in Hepatocellular Carcinoma Cells.  Oda Y, Hidaka M, Suzuki A.  Biol. Pharm. Bull.  2017  40:2005-2009  PubMed ID: 28855448
10490  Nicotine transport in lung and non-lung epithelial cells.  Takano M, Kamei H, Nagahiro M, Kawami M, Yumoto R.  Life Sci.  2017  188:76-82  PubMed ID: 28866099
10491  SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes.  Inoue C, Zhao C, Tsuduki Y, Udono M, Wang L, Nomura M, Katakura Y.  NPJ Aging Mech Dis  2017  3:11  PubMed ID: 28868154
10494  Low dose of alcohol attenuates pro-atherosclerotic activity of thrombin.  Toda M, Totoki T, Nakamura C, Yasuma T, D' Alessandro-Gabazza CN, Mifuji-Moroka R, Nishihama K, Iwasa M, Horiki N, Gabazza EC, Takei Y.  Atherosclerosis  2017  265:215-224  PubMed ID: 28923781
10495  Sake lees hydrolysate protects against acetaminophen-induced hepatotoxicity via activation of the Nrf2 antioxidant pathway.  Kawakami K, Moritani C, Uraji M, Fujita A, Kawakami K, Hatanaka T, Suzaki E, Tsuboi S.  J Clin Biochem Nutr  2017  61:203-209  PubMed ID: 29203962
10519  Inhibition of fucosylation by 2-fluorofucose suppresses human liver cancer HepG2 cell proliferation and migration as well as tumor formation.  Zhou Y, Fukuda T, Hang Q, Hou S, Isaji T, Kameyama A, Gu J.  Sci Rep  2017  7:11563  PubMed ID: 28912543
10531  Telmisartan inhibits hepatocellular carcinoma cell proliferation in vitro by inducing cell cycle arrest.  Oura K, Tadokoro T, Fujihara S, Morishita A, Chiyo T, Samukawa E, Yamana Y, Fujita K, Sakamoto T, Nomura T, Yoneyama H, Kobara H, Mori H, Iwama H, Okano K, Suzuki Y, Masaki T.  Oncol. Rep.  2017  38:2825-2835  PubMed ID: 29048654
10552  Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships.  Okubo S, Uto T, Goto A, Tanaka H, Nishioku T, Yamada K, Shoyama Y.  Am. J. Chin. Med.  2017  45:1497-1511  PubMed ID: 29025293
10622  Prognostic significance of promoter DNA hypermethylation of the cysteine dioxygenase 1 (CDO1) gene in primary gallbladder cancer and gallbladder disease.  Igarashi K, Yamashita K, Katoh H, Kojima K, Ooizumi Y, Nishizawa N, Nishiyama R, Kawamata H, Tajima H, Kaizu T, Kumamoto Y, Watanabe M.  PLoS ONE  2017  12:e0188178  PubMed ID: 29161283
10634  Detection of hepatitis B virus DNA and HBsAg from postmortem blood and bloodstains.  Hara J, Tanaka Y, Kaneko H, Itoh Y, Ikegaya H.  Arch. Virol.  2018  163:633-637  PubMed ID: 29198036
10641  Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.  Kaji K, Nishimura N, Seki K, Sato S, Saikawa S, Nakanishi K, Furukawa M, Kawaratani H, Kitade M, Moriya K, Namisaki T, Yoshiji H.  Int. J. Cancer  2018  142:1712-1722  PubMed ID: 29205334
10660  β-carotene and retinol reduce benzo[a]pyrene-induced mutagenicity and oxidative stress via transcriptional modulation of xenobiotic metabolizing enzymes in human HepG2 cell line.  Darwish WS, Ikenaka Y, Nakayama S, Mizukawa H, Thompson LA, Ishizuka M.  Environ Sci Pollut Res Int  2018  25:6320-6328  PubMed ID: 29247416
10774  Development of a perfusable 3D liver cell cultivation system via bundling-up assembly of cell-laden microfibers.  Yajima Y, Lee CN, Yamada M, Utoh R, Seki M.  J. Biosci. Bioeng.  2018  126(1):111-118  PubMed ID: 29502942
10786  Origami-based self-folding of co-cultured NIH/3T3 and HepG2 cells into 3D microstructures.  He Q, Okajima T, Onoe H, Subagyo A, Sueoka K, Kuribayashi-Shigetomi K.  Sci Rep  2018  8:4556  PubMed ID: 29540810
10847  Cysteine dioxygenase type 1 (CDO1) gene promoter methylation during the adenoma-carcinoma sequence in colorectal cancer.  Kojima K, Nakamura T, Ohbu M, Katoh H, Ooizumi Y, Igarashi K, Ishii S, Tanaka T, Yokoi K, Nishizawa N, Yokota K, Kosaka Y, Sato T, Watanabe M, Yamashita K.  PLoS ONE  2018  13:e0194785  PubMed ID: 29746493
10930  Bioactive Compounds from the Leaves of Lumnitzera racemosa against Acetaminophen-induced Liver damage in vitro    Journal of Arid Land Studies  2016  26, 179 - 182 
10936  Cell Sheet Fabrication Using RGD Peptide-Coupled Alginate Hydrogels Fabricated by an Electrodeposition Method    Chem. Lett.  2017  46, 605–608 
10959  Induction of Drug Resistance in Human Hepatoma Cells Cultured on a Silicate Fiber-Based 3D Scaffold    Adv Biochem Biotechnol  2017  112 
10975  Collagen Microparticle-mediated 3D Cell Organization: A Facile Route to Bottom-Up Engineering of Thick and Porous Tissues    ACS Biomater. Sci. Eng.  2017  3, 2144–2154 
10985  Effects of Cytokines and Immunosuppressants on the Production of Serum Amyloid A Protein and C-reactive    Dokkyo Journal of Medical Sciences  2003  30(2):131-139 
10990  CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element    Fundamental Toxicological Sciences  2017  4, 229-239 
11025  Isolation of activating factors of serotonin N-acetyltransferase from rice peptides    Journal of Functional Foods  2018  41, 148-154 
11089  Immune responses of human T lymphocytes to novel hepatitis B virus-derived peptides.  Yamamiya D, Mizukoshi E, Kaji K, Terashima T, Kitahara M, Yamashita T, Arai K, Fushimi K, Honda M, Kaneko S.  PLoS ONE  2018  13(6):e0198264  PubMed ID: 29856876
11139  Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein.  Saikawa S, Kaji K, Nishimura N, Seki K, Sato S, Nakanishi K, Kitagawa K, Kawaratani H, Kitade M, Moriya K, Namisaki T, Mitoro A, Yoshiji H.  Cancer Lett.  2018  434:120-129  PubMed ID: 30031758
11113  Profiling of N-linked glycans from 100 cells by capillary electrophoresis with large-volume dual preconcentration by isotachophoresis and stacking.  Kawai T, Ota N, Imasato A, Shirasaki Y, Otsuka K, Tanaka Y.  J Chromatogr A  2018  1565:138-144  PubMed ID: 29945790
11160  In Vitro Evaluation of Cytotoxic Activities of Marketed Herbal Products in Ghana.  Languon S, Tuffour I, Quayson EE, Appiah-Opong R, Quaye O.  J Evid Based Integr Med  2018    PubMed ID: 30088418
11292  A Three-dimensional Cell Culture Method with a Micromesh Sheet and Its Application to Hepatic Cells.  Hori T, Kurosawa O.  Tissue Eng Part C Methods  2018    PubMed ID: 30412042
4452  Comparative Gene Expression Profiling in Cultured Cell Lines after Treatment with Wasabi-derived Isothiocyanates  Phoebe Trio1, Atsuyoshi Kawahara, Satoru Fujisaki, De-Xing Hou  KIMIKA  2018  29, 1-10 
4224  Effects of Vitamin K₂ on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR.  Sultana H, Watanabe K, Rana MM, Takashima R, Ohashi A, Komai M, Shirakawa H.  Nutrients  2018    PubMed ID: 30060524
4225  Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors.  Takashima Y, Horisawa K, Udono M, Ohkawa Y, Suzuki A.  Cancer Sci.  2018    PubMed ID: 30220099
4483  Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response.  Anusornvongchai T, Nangaku M, Jao TM, Wu CH, Ishimoto Y, Maekawa H, Tanaka T, Shimizu A, Yamamoto M, Suzuki N, Sassa R, Inagi R.  Kidney Int.  2018  94(3):536-550  PubMed ID: 29887316
4484  Edaravone, a cytoprotective drug, enhances transgene expression mediated by lipoplexes in HepG2 cells and mice.  Wang S, Fumoto S, Miyamoto H, Tanaka M, Nishida K.  Int J Pharm  2018  548(1):173-181  PubMed ID: 29969708
5357  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.  Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.  Mol Cell  2019  76(5):797-810  PubMed ID: 31606272
6039  Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.  Badr H, Kozai D, Sakaguchi R, Numata T, Mori Y.  Front Pharmacol  2016  7:19  PubMed ID: 26903865
11522  Aluminum chloride causes 5-fluorouracil resistance in hepatocellular carcinoma HepG2 cells.  Li M, Cui ZG, Zakki SA, Feng Q, Sun L, Feril LB Jr, Inadera H.  J. Cell. Physiol.  2019    PubMed ID: 30993729
11857  Importance of the Proximity and Orientation of Ligand-Linkage to the Design of Cinnamate-GW9662 Hybrid Compounds as Covalent PPARγ Agonists.  Utsugi Y, Kobuchi H, Kawamura Y, Atito ASA, Nagao M, Isoda H, Miyamae Y.  Molecules  2019    PubMed ID: 31137814
6837  Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves.  Bouallagui Z, Mahmoudi A, Maalej A, Hadrich F, Isoda H, Sayadi S.  Anticancer Agents Med Chem  2019  19(13):1651-1657  PubMed ID: 31038081



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