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19831
Yamaguchi F, Sakane H, Akasaki K.
Comparative study of the steady-state subcellular distribution of lysosome-associated membrane glycoprotein-2 (LAMP-2) isoforms with GYXXΦ-type tyrosine-based motifs that interact differently with four adaptor protein (AP) complexes
J Biochem
2024
175(3):275-287
PubMed ID: 37983719
DOI: 10.1093/jb/mvad096
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19873
Kataoka H, Akiyoshi T, Uchida Y, Imaoka A, Terasaki T, Ohtani H.
The effects of N-glycosylation on the expression and transport activity of OATP1A2 and OATP2B1
J Pharm Sci
2024
S0022-3549(24)00058-3
PubMed ID: 38432624
DOI: 10.1016/j.xphs.2024.02.012
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19956
Mixich L, Boonstra E, Masuda K, Li SW, Nakashima Y, Meng F, Sakata M, Goda T, Uchida S, Cabral H.
Ionizable Polymeric Micelles with Phenylalanine Moieties Enhance Intracellular Delivery of Self-Replicating RNA for Long-Lasting Protein Expression In Vivo
Biomacromolecules
2024
Jan 5
PubMed ID: 38181450
DOI: 10.1021/acs.biomac.3c01102
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21560
Wang A, Uchida K, Yokoyama A, Higashino F, Yasuda M.
Human adenovirus oncolytic properties and the inhibitory role of E4 orf4 and E4 orf6/7 on endogenously activated NF-κB.
Biochem Biophys Rep
2024
37:101616
PubMed ID: 38205184
DOI: 10.1016/j.bbrep.2023.101616
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21700
Katayama K, Ito J, Murakami R, Yamashita A, Sasajima H, Narahashi S, Chiba J, Yamamoto I, Fujii W, Tochigi Y, Suzuki H.
Mutation of the Thap4 gene causes dwarfism and testicular anomalies in rats and mice.
Mamm Genome
2024
PubMed ID: 38658415
DOI: 10.1007/s00335-024-10041-8
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21741
Kato S, Tamura K, Masuda Y, Konishi M, Yamanaka K, Oikawa T.
A novel type IIb L-asparaginase from Latilactobacillus sakei LK-145: characterization and application.
Arch Microbiol
2024
206(6):266
PubMed ID: 38761213
DOI: 10.1007/s00203-024-03979-5
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21778
Imamura I, Kiyama R.
Potential involvement of KANK1 haploinsufficiency in centrosome aberrations.
Biochim Biophys Acta Gen Subj
2024
130648
PubMed ID: 38830559
DOI: 10.1016/j.bbagen.2024.130648
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21794
Zhou J, Murata H, Tomonobu N, Mizuta N, Yamakawa A, Yamamoto KI, Kinoshita R, Sakaguchi M.
S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway.
In Vitro Cell Dev Biol Anim
2024
PubMed ID: 38842658
DOI: 10.1007/s11626-024-00930-2
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21796
Hara Y, Ichiraku A, Matsuda T, Sakane A, Sasaki T, Nagai T, Horikawa K.
High-affinity tuning of single fluorescent protein-type indicators by flexible linker length optimization in topology mutant.
Commun Biol
2024
PubMed ID: 38851844
DOI: 10.1038/s42003-024-06394-0
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21798
Ichiyama-Kobayashi S, Hata K, Wakamori K, Takahata Y, Murakami T, Yamanaka H, Takano H, Yao R, Uzawa N, Nishimura R.
Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.
JCI Insight
2024
9(11)
PubMed ID: 38855864
DOI: 10.1172/jci.insight.175486
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21799
Yamamoto R, Segawa R, Kato H, Niino Y, Sato T, Hiratsuka M, Hirasawa N.
Identification of amino acids in transmembrane domains of mutated cytokine receptor-like factor 2 and interleukin-7 receptor α required for constitutive signal transduction.
Biochim Biophys Acta Biomembr
2024
184359
PubMed ID: 38862034
DOI: 10.1016/j.bbamem.2024.184359
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21837
Maruyama Y, Ohsawa Y, Suzuki T, Yamauchi Y, Ohno K, Inoue H, Yamamoto A, Hayashi M, Okuhara Y, Muramatsu W, Namiki K, Hagiwara N, Miyauchi M, Miyao T, Ishikawa T, Horie K, Hayama M, Akiyama N, Hirokawa T, Akiyama T.
Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist.
Nat Commun
2024
15(1):5743
PubMed ID: 39030171
DOI: 10.1038/s41467-024-49893-8
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21962
Okamoto Y, Kitakaze K, Takenouchi Y, Matsui R, Koga D, Miyashima R, Ishimaru H, Tsuboi K.
GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression.
Biochim Biophys Acta Mol Cell Res
2024
1871(7):119798
PubMed ID: 39047914
DOI: 10.1016/j.bbamcr.2024.119798
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22008
Kawaue H, Matsubara T, Nagano K, Ikedo A, Rojasawasthien T, Yoshimura A, Nakatomi C, Imai Y, Kakuta Y, Addison WN, Kokabu S.
KIF22 regulates mitosis and proliferation of chondrocyte cells.
iScience
2024
27(7):110151
PubMed ID: 38989461
DOI: 10.1016/j.isci.2024.110151
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22009
Ishizawa M, Takano M, Kittaka A, Matsumoto T, Makishima M.
2α-Substituted Vitamin D Derivatives Effectively Enhance the Osteoblast Differentiation of Dedifferentiated Fat Cells.
Biomolecules
2024
14(6)
PubMed ID: 38927109
DOI: 10.3390/biom14060706
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22068
Kato S, Deguchi K, Obana M, Fujio Y, Fukuda Y, Inoue T.
Metabolite phosphatase from anhydrobiotic tardigrades.
FEBS J
2024
PubMed ID: 39417615
DOI: 10.1111/febs.17296
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22088
Oyama S, Zhang H, Ferdous R, Tomochika Y, Chen B, Jiang S, Islam MS, Hasan MM, Zhai Q, Waliullah ASM, Ping Y, Yan J, Mimi MA, Zhang C, Aramaki S, Takanashi Y, Kahyo T, Hashizume Y, Kaneda D, Setou M.
UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies Their Intracellular Sorting.
Neurol Int
2024
16(6):1175-1188
PubMed ID: 39449505
DOI: 10.3390/neurolint16060089
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22131
Kawataki S, Kubota Y, Katayama K, Imoto S, Takekawa M.
GADD45β-MTK1 signaling axis mediates oncogenic stress-induced activation of the p38 and JNK pathways.
Cancer Sci
2024
PubMed ID: 39526327
DOI: 10.1111/cas.16389
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22236
Lin N, Miyamoto K, Ogawara T, Sakurai S, Kizaka-Kondoh S, Kadonosono T.
Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing
Commun Biol
2024
7(1):652
PubMed ID: 38806676
DOI: 10.1038/s42003-024-06363-7
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22237
Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S.
Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
Elife
2024
12:RP92342
PubMed ID: 38512724
DOI: 10.7554/eLife.92342
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22336
Kaneda-Nakashima K, Shirakami Y, Hisada K, Feng S, Kadonaga Y, Ooe K, Watabe T, Manabe Y, Shimoyama A, Murakami M, Toyoshima A, Haba H, Kanai Y, Fukase K.
Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211
Int J Mol Sci
2024
25(22):12386
PubMed ID: 39596451
DOI: 10.3390/ijms252212386
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17776
Arasawa T, Hiwasa T, Kagaya A, Maruyama T, Uesato M, Kano M, Kobayashi S, Takizawa H, Iwase K, Nomura F, Matsushita K, Matsubara H.
Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels
BMC Cancer
2023
23(1):356
PubMed ID: 37072777
DOI: 10.1186/s12885-023-10845-y
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17778
Shinya Usui, Qiunan Zhu, Hisakazu Komori, Yui Iwamoto, Takumi Nishiuchi, Yoshiyuki Shirasaka, Ikumi Tamai
Apple-derived extracellular vesicles modulate the expression of human intestinal bile acid transporter ASBT/SLC10A2 via downregulation of transcription factor RARα
Drug Metabolism and Pharmacokinetics
2023
DOI: 10.1016/j.dmpk.2023.100512
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19535
Yan J, Zhang H, Tomochika Y, Chen B, Ping Y, Islam MS, Aramaki S, Sato T, Nagashima Y, Nakamura T, Kahyo T, Kaneda D, Ogawa K, Yoshida M, Setou M.
UBL3 Interaction with α-Synuclein Is Downregulated by Silencing MGST3
Biomedicines
2023
11(9):2491
PubMed ID: 37760932
DOI: 10.3390/biomedicines11092491
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19666
Aso A, Nabetani H, Matsuura Y, Kadonaga Y, Shirakami Y, Watabe T, Yoshiya T, Mochizuki M, Ooe K, Kawakami A, Jinno N, Toyoshima A, Haba H, Wang Y, Cardinale J, Giesel FL, Shimoyama A, Kaneda-Nakashima K, Fukase K.
Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine
Int J Mol Sci
2023
24(10):8701
PubMed ID: 37240044
DOI: 10.3390/ijms24108701
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19686
Takeuchi M, Nishisho T, Toki S, Kawaguchi S, Tamaki S, Oya T, Uto Y, Katagiri T, Sairyo K.
Blue light induces apoptosis and autophagy by promoting ROS-mediated mitochondr
Cancer Med
2023
12(8):9668-9683
PubMed ID: 36722116
DOI: 10.1002/cam4.5664
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19701
Yamamoto R, Segawa R, Liu J, Isaji T, Gu J, Hiratsuka M, Hirasawa N.
Effect of N-glycosylation on constitutive signal transduction by mutated cytokine receptor-like factor 2
Biochim Biophys Acta Gen Subj
2023
1867(11):130465
PubMed ID: 37748663
DOI: 10.1016/j.bbagen.2023.130465
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19785
Yamamoto H, Tanaka Y, Sawada M, Kihara S.
ERRα Attenuates Vascular Inflammation via Enhanced NFκB Degradation Pathway
Endocrinology
2023
164(3):bqac212
PubMed ID: 36534970
DOI: 10.1210/endocr/bqac212
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19803
Murase W, Kubota A, Ikeda-Araki A, Terasaki M, Nakagawa K, Shizu R, Yoshinari K, Kojima H.
Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays
Toxicology
2023
494:153577
PubMed ID: 37302725
DOI: 10.1016/j.tox.2023.153577
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19809
Tezuka M, Yonekubo-Awaka S, Tamai Y, Tsuchioka K, Kobayashi K, Kuramochi Y, Tatemichi S, Nagasawa T, Kiguchi S.
Suppression of hypothalamic-pituitary-gonadal function by linzagolix in benign prostatic hyperplasia and polycystic ovary syndrome animal models
Clin Exp Pharmacol Physiol
2023
50(11):914-923
PubMed ID: 37622483
DOI: 10.1111/1440-1681.13817
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19876
Maekawa K, Ishizawa M, Ikawa T, Sajiki H, Matsumoto T, Tokiwa H, Makishima M, Yamada S.
Syntheses of 25-Adamantyl-25-alkyl-2-methylidene-1α,25-dihydroxyvitamin D3 Derivatives with Structure-Function Studies of Antagonistic and Agonistic Active Vitamin D Analogs
Biomolecules
2023
13(7):1082
PubMed ID: 37509118
DOI: 10.3390/biom13071082
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19899
Nakamura T, Sugeno N, Hasegawa T, Ikeda K, Yoshida S, Ishiyama S, Sato K, Takeda A, Aoki M.
Alpha-synuclein promotes PRMT5-mediated H4R3me2s histone methylation by interacting with the BAF complex
FEBS J
2023
Dec 17
PubMed ID: 38105619
DOI: 10.1111/febs.17037
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19947
Moriizumi H, Kubota Y, Tsuchiya T, Naka R, Takekawa M.
Caspase 3-specific cleavage of MEK1 suppresses ERK signaling and sensitizes cells to stress-induced apoptosis
FEBS Open Bio
2023
13(4):684-700
PubMed ID: 36776127
DOI: 10.1002/2211-5463.13574
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19987
Miyajima Y, Noguchi-Yachide T, Ochiai K, Fujii S.
Physicochemical characterization of B-hydroxyphenyl phosphine borane derivatives and their evaluation as nuclear estrogen receptor ligands
RSC Med Chem
2023
15(1):119-12
PubMed ID: 38283218
DOI: 10.1039/d3md00350g
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21018
Nakashima KI, Okamura M, Matsumoto I, Kameda N, Tsuboi T, Yamaguchi E, Itoh A, Inoue M.
Regulation of adipogenesis through retinoid X receptor and/or peroxisome proliferator-activated receptor by designed lignans based on natural products in 3T3-L1 cells.
J Nat Med
2023
PubMed ID: 36607539
DOI: 10.1007/s11418-022-01674-7
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21023
Nakamura Y, Aizawa C, Kawata H, Nakanishi T.
N-glycosylation Modifies Prostaglandin E2 Uptake by Reducing Cell Surface Expression of SLCO2A1.
Prostaglandins Other Lipid Mediat
2023
106714
PubMed ID: 36706979
DOI: 10.1016/j.prostaglandins.2023.106714
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21041
Shiraki A, Shimizu S.
The molecular associations in clathrin-coated pit regulate β-arrestin-mediated MAPK signaling downstream of μ-opioid receptor.
Biochem Biophys Res Commun
2023
640:64-72
PubMed ID: 36502633
DOI: 10.1016/j.bbrc.2022.11.098
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21068
Yamakado N, Okuda S, Tobiume K, Uetsuki R, Ono S, Mizuta K, Nakagawa T, Aikawa T.
Chemical inhibition of LSD1 leads to epithelial to mesenchymal transition in vitro of an oral squamous cell carcinoma OM-1 cell line via release from LSD1-dependent suppression of ZEB1.
Biochem Biophys Res Commun
2023
647:23-29
PubMed ID: 36709669
DOI: 10.1016/j.bbrc.2023.01.062
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21100
Suzuki Y, Nakamoto C, Watanabe-Iida I, Watanabe M, Takeuchi T, Sasaoka T, Abe M, Sakimura K.
Quantitative analysis of NMDA receptor subunits proteins in mouse brain.
Neurochem Int
2023
105517
PubMed ID: 36913980
DOI: 10.1016/j.neuint.2023.105517
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21116
Komuro R, Honda Y, Yanaizu M, Nagahama M, Kino Y.
Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins.
Cells
2023
12(4)
PubMed ID: 36831269
DOI: 10.3390/cells12040602
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21153
Yang W, Miyazaki T, Nakagawa Y, Boonstra E, Masuda K, Nakashima Y, Chen P, Mixich L, Barthelmes K, Matsumoto A, Mi P, Uchida S, Cabral H.
Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π-π stacking-assisted micellar assembly.
Sci Technol Adv Mater
2023
24(1):2170164
PubMed ID: 36950277
DOI: 10.1080/14686996.2023.2170164
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21214
Ohba K, Sehara Y, Enoki T, Mineno J, Ozawa K, Mizukami H.
Adeno-associated virus vector system controlling capsid expression improves viral quantity and quality.
iScience
2023
26(4):106487
PubMed ID: 37096037
DOI: 10.1016/j.isci.2023.106487
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21246
Ishiyama S, Hasegawa T, Sugeno N, Kobayashi J, Yoshida S, Miki Y, Wakabayashi K, Fukuda M, Kawata Y, Nakamura T, Sato K, Ezura M, Kikuchi A, Takeda A, Aoki M.
Sortilin acts as an endocytic receptor for α-synuclein fibril.
FASEB J
2023
37(7):e23017
PubMed ID: 37272890
DOI: 10.1096/fj.202201605RR
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21270
Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.
The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.
PLoS One
2023
18(6):e0287249
PubMed ID: 37352201
DOI: 10.1371/journal.pone.0287249
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21333
Kogaki T, Hase H, Tanimoto M, Tashiro A, Kitae K, Ueda Y, Jingushi K, Tsujikawa K.
ALKBH4 is a novel enzyme that promotes translation through modified uridine regulation.
J Biol Chem
2023
105093
PubMed ID: 37507018
DOI: 10.1016/j.jbc.2023.105093
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21384
Nishida K, Wang G, Kobatake E, Mie M.
Sensitive Detection of Tumor Cells Using Protein Nanoparticles with Multiple Displays of DNA Aptamers and Bioluminescent Reporters.
ACS Biomater Sci Eng
2023
PubMed ID: 37642536
DOI: 10.1021/acsbiomaterials.3c00712
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21453
Yajima K, Akiyoshi T, Sakamoto K, Suzuki Y, Oka T, Imaoka A, Yamamura H, Kurokawa J, Ohtani H.
Determination of single-molecule transport activity of OATP2B1 by measuring the number of transporter molecules using electrophysiological approach.
J Pharmacol Sci
2023
153(3):153-160
PubMed ID: 37770156
DOI: 10.1016/j.jphs.2023.08.008
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21467
Suzuki S, Saito S, Narushima Y, Kodani S, Kagaya N, Suenaga H, Shin-Ya K, Arai MA.
Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation.
J Antibiot (Tokyo)
2023
PubMed ID: 37938761
DOI: 10.1038/s41429-023-00673-4
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21485
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S, Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K, Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki S, Suzuki T, Suzuki T.
Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell
2023
PubMed ID: 37992713
DOI: 10.1016/j.cell.2023.10.026
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21508
Kenji Ohba, Hiroaki Mizukami
Protocol for producing an adeno-associated virus vector by controlling capsid expression timing
STAR Protocols
2023
4:102542
PubMed ID: 38103199
DOI: 10.1016/j.xpro.2023.102542
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21534
Ohkawa Y, Kanto N, Nakano M, Fujinawa R, Kizuka Y, Johnson EL, Harada Y, Tamura JI, Taniguchi N.
Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model.
J Biol Chem
2023
299(8):105052
PubMed ID: 37454739
DOI: 10.1016/j.jbc.2023.105052
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22290
Chen B, Hasan MM, Zhang H, Zhai Q, Waliullah ASM, Ping Y, Zhang C, Oyama S, Mimi MA, Tomochika Y, Nagashima Y, Nakamura T, Kahyo T, Ogawa K, Kaneda D, Yoshida M, Setou M.
UBL3 Interacts with Alpha-Synuclein in Cells and the Interaction Is Downregulated by the EGFR Pathway Inhibitor Osimertinib
Biomedicines
2023
11(6):1685
PubMed ID: 37371780
DOI: 10.3390/biomedicines11061685
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17537
Emiko Kinoshita-Kikuta, Yoko Ino, Yayoi Kimura, Tomoko Akiyama, Eiji Kinoshita, Tohru Koike
Use of Escherichia coli expression system for analyzing kinase motifs
Journal of Electrophoresis
2022
66:13-20
DOI: 10.2198/jelectroph.66.13
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17583
Han H, Akiyoshi T, Morita T, Kataoka H, Katayama K, Yajima K, Imaoka A, Ohtani H.
Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants
Drug Metab Pharmacokinet
2022
47:100470
PubMed ID: 36116173
DOI: 10.1016/j.dmpk.2022.100470
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17609
Yoshihara A, Kawasaki H, Masuno H, Takada K, Numoto N, Ito N, Hirata N, Kanda Y, Ishizawa M, Makishima M, Kagechika H, Tanatani A.
Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists
Biomolecules
2022
12(1):130
PubMed ID: 35053278
DOI: 10.3390/biom12010130
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17708
Nakamura Y, Kozakai H, Nishio T, Yoshida K, Nakanishi T.
Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1
Drug Metab Pharmacokinet
2022
44:100452
PubMed ID: 35299026
DOI: 10.1016/j.dmpk.2022.100452
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17798
Chen P, Yang W, Hong T, Miyazaki T, Dirisala A, Kataoka K, Cabral H.
Nanocarriers escaping from hyperacidified endo/lysosomes in cancer cells allow tumor-targeted intracellular delivery of antibodies to therapeutically inhibit c-MYC
Biomaterials
2022
288:121748
PubMed ID: 36038419
DOI: 10.1016/j.biomaterials.2022.121748
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15439
Shams R, Matsukawa A, Ochi Y, Ito Y, Miyatake H.
In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1
J Med Chem
2022
Jun 30
PubMed ID: 34191518
DOI: 10.1021/acs.jmedchem.1c00536
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20553
Urabe T, Miyoshi H, Narasaki S, Yanase Y, Uchida K, Noguchi S, Hide M, Tsutsumi YM, Sakai N.
Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic.
PLoS One
2022
17(2):e0263395
PubMed ID: 35104283
DOI: 10.1371/journal.pone.0263395
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16391
Sakamoto T, Yu Z, Otani Y.
Dual-Color Fluorescence Switch-On Probe for Imaging G-Quadruplex and Double-Stranded DNA in Living Cells
Anal Chem
2022
Mar 2
PubMed ID: 35234461
DOI: 10.1021/acs.analchem.1c04804
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20612
Yamatoya K, Nagai Y, Teramoto N, Kang W, Miyado K, Nakata K, Yagi T, Miyamoto Y.
Cryopreservation of undifferentiated and differentiated human neuronal cells.
Regen Ther
2022
19:58-68
PubMed ID: 35059480
DOI: 10.1016/j.reth.2021.12.007
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20616
Liu JY, Inoshita T, Shiba-Fukushima K, Yoshida S, Ogata K, Ishihama Y, Imai Y, Hattori N.
Ubiquitination at the lysine 27 residue of the parkin ubiquitin-like domain is suggestive of a new mechanism of parkin activation.
Hum Mol Genet
2022
PubMed ID: 35313349
DOI: 10.1093/hmg/ddac064
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20649
Liu Y, Nisisako T.
Microfluidic generation of monodispersed Janus alginate hydrogel microparticles using water-in-oil emulsion reactant.
Biomicrofluidics
2022
16(2):024101
PubMed ID: 35282035
DOI: 10.1063/5.0077916
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20657
Fukumoto Y, Matsuhashi K, Tanaka YK, Suzuki N, Ogra Y.
Band 3/anion exchanger 1/solute carrier family 4 member 1 expression as determinant of cellular sensitivity to selenite exposure.
Biochem Biophys Rep
2022
29:101223
PubMed ID: 35146136
DOI: 10.1016/j.bbrep.2022.101223
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20701
Yonezawa H, Ikeda A, Takahashi R, Endo H, Sugawara Y, Goto M, Kanno M, Ogawa S, Nakamura K, Ujiie H, Iwatsuki M, Hirose T, Sunazuka T, Uehara Y, Nishiya N.
Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases.
iScience
2022
25(3):103912
PubMed ID: 35530256
DOI: 10.1016/j.isci.2022.103912
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20774
Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M.
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun
2022
13(1):4063
PubMed ID: 35831322
DOI: 10.1038/s41467-022-31690-w
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20796
Honda T, Kawasaki N, Yanagihara R, Tamura R, Murakami K, Ichimiya T, Matsumoto N, Nishihara S, Yamamoto K.
Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).
PLoS One
2022
17(7):e0268485
PubMed ID: 35901072
DOI: 10.1371/journal.pone.0268485
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20807
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Sulfation of sialic acid is ubiquitous and essential for vertebrate development.
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Molecular Cloning and Biochemical Characterization of Medaka (Oryzias Latipes) Lysosomal neu4 Sialidase
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β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.
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Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B
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Molecular cloning and characterization of canine fractalkine and its receptor CX3CR1
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Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification.
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Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages
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Naofen, a novel WD40-repeat protein, mediates spontaneous and tumor necrosis factor-induced apoptosis.
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Biochem Biophys Res Commun
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Kazunori Yamaguchi, Koichi Koseki, Momo Shiozaki, Yukiko Shimada, Tadashi Wada, Taeko Miyagi
Regulation of Plasma-Membrane-Associated Sialidase NEU3 Gene by Sp1/Sp3 Transcription Factors
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Cryptochrome Genes Are Highly Expressed in the Ovary of the African Clawed Frog, Xenopus Tropicalis
PLoS One
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Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway
Mol Immunol
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47(6):1283-91
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Yoshikawa F, Banno Y, Otani Y, Yamaguchi Y, Nagakura-Takagi Y, Morita N, Sato Y, Saruta C, Nishibe H, Sadakata T, Shinoda Y, Hayashi K, Mishima Y, Baba H, Furuichi T.
Phospholipase D family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia
PLoS One
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J. Pharmacol. Sci.
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Forkhead transcription factor Foxo1 is essential for adipocyte differentiation.
In Vitro Cell. Dev. Biol. Anim.
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A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.
Clin. Cancer Res.
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Interference with cellular differentiation by D-serine through antagonism at N-methyl-D-aspartate receptors composed of NR1 and NR3A subunits in chondrocytes.
J. Cell. Physiol.
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Interference by adrenaline with chondrogenic differentiation through suppression of gene transactivation mediated by Sox9 family members.
Bone
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45:568-78
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Shinkai Y, Sumi D, Toyama T, Kaji T, Kumagai Y.
Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.
Toxicol. Appl. Pharmacol.
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237:232-6
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Miki Y, Itoh T, Hirano K, Eda S, Hayashi A, Yamanaka M, Beppu M.
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Novel high-throughput screening system for identifying STAT3-SH2 antagonists.
Biochem. Biophys. Res. Commun.
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Calcineurin regulates phosphorylation status of transcription factor osterix.
Biochem. Biophys. Res. Commun.
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Hsp105beta upregulates hsp70 gene expression through signal transducer and activator of transcription-3
FEBS J
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Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N.
Enzymological analysis of mutant protein kinase Cgamma causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis
J Biol Chem
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Matsubara T, Kida K, Yamaguchi A, Hata K, Ichida F, Meguro H, Aburatani H, Nishimura R, Yoneda T.
BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation
J Biol Chem
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Shibata T, Kokubu A, Gotoh M, Ojima H, Ohta T, Yamamoto M, Hirohashi S.
Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer
Gastroenterology
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Nemoto Y, Zhou YM, Tatsumi E, Nakayama Y.
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Bioconjug Chem
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Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1
Anal Biochem
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Sakurai M, Misawa T, Shiba H, Iida T, Ohashi T, Yanaga K.
A novel approach for gene transduction with adenovirus vector and the fibrin glue system.
Anticancer Res
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Toyoda E, Doi R, Kami K, Mori T, Ito D, Koizumi M, Kida A, Nagai K, Ito T, Masui T, Wada M, Tagawa M, Uemoto S.
Midkine promoter-based conditionally replicative adenovirus therapy for midkine-expressing human pancreatic cancer
J Exp Clin Cancer Res
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Kira Y1, Nishikawa M.
The identification and characterization of a new GTP-binding protein (Gbp45) involved in cell proliferation and death related to mitochondrial function.
Cell Mol Biol Lett
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Hata K, Nishimura R, Muramatsu S, Matsuda A, Matsubara T, Amano K, Ikeda F, Harley VR, Yoneda T.
Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice.
J Clin Invest
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JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts
J Bone Miner Res
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Nakao N, Ono H, Yamamura T, Anraku T, Takagi T, Higashi K, Yasuo S, Katou Y, Kageyama S, Uno Y, Kasukawa T, Iigo M, Sharp PJ, Iwasawa A, Suzuki Y, Sugano S, Niimi T, Mizutani M, Namikawa T, Ebihara S, Ueda HR, Yoshimura T.
Thyrotrophin in the pars tuberalis triggers photoperiodic response
Nature
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Shimizu N, Yoshikawa N, Wada T, Handa H, Sano M, Fukuda K, Suematsu M, Sawai T, Morimoto C, Tanaka H.
Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes by hexamethylene bisacetamide-inducible protein 1
Mol Endocrinol
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Cys669-Cys713 disulfide bridge formation is a key to dystroglycan cleavage and subunit association
Genes Cells
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Takada E, Okahira S, Sasai M, Funami K, Seya T, Matsumoto M.
C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission
Mol Immunol
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Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling
Cancer Res
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67(3):911-8
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Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).
Genes Chromosomes Cancer
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CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways.
Biochem Biophys Res Commun
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PTEN reduces cuff-induced neointima formation and proinflammatory cytokines
Am J Physiol Heart Circ Physiol
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Suppression of centrosome amplification after DNA damage depends on p27 accumulation.
Cancer Res
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Molecular cloning, mRNA expression, and immunocytochemical localization of a putative blue-light photoreceptor CRY4 in the chicken pineal gland.
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RNAi silencing of exogenous and endogenous reporter genes using a macrocyclic octaamine as a "compact" siRNA carrier. Studies on the nonsilenced residual activity.
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Sasai M, Shingai M, Funami K, Yoneyama M, Fujita T, Matsumoto M, Seya T.
NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction
J Immunol
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Kanno T, Yamamoto H, Yaguchi T, Hi R, Mukasa T, Fujikawa H, Nagata T, Yamamoto S, Tanaka A, Nishizaki T.
The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site
J Lipid Res
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A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.
Oncogene
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Osamu Hashimoto, Yuuki Ushiro, Kazunari Sekiyama, Osamu Yamaguchi, Kazuki Yoshioka, Ken-ichiro Mutoh, Yoshihisa Hasegawa
Impaired Growth of Pancreatic Exocrine Cells in Transgenic Mice Expressing Human Activin betaE Subunit
Biochem Biophys Res Commun
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341(2):416-24
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Ishii N, Ozaki K, Sato H, Mizuno H, Susumu Saito, Takahashi A, Miyamoto Y, Ikegawa S, Kamatani N, Hori M, Satoshi Saito, Nakamura Y, Tanaka T.
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction
J Hum Genet
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Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor.
J Biol Chem
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Hata, Kenji, Nishimura, Riko, Ueda, Mio, Ikeda, Fumiyo, Matsubara, Takuma, Ichida, Fumitaka, Hisada, Kunihiro, Nokubi, Takashi, Yamaguchi, Akira, Yoneda, Toshiyuki
A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes.
Mol Cell Biol
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25:1971-9
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Nagayoshi, Ryusaku, Nagai, Taku, Matsushita, Kakushi, Sato, Katsuaki, Sunahara, Nobuhiko, Matsuda, Takemasa, Nakamura, Tadashi, Komiya, Setsuro, Onda, Masanori, Matsuyama, Takami
Effectiveness of anti-folate receptor beta antibody conjugated with truncated Pseudomonas exotoxin in the targeting of rheumatoid arthritis synovial macrophages.
Arthritis Rheum
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150-kD oxygen-regulated protein is an essential factor for insulin release
Pancreas
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A multifunctional shuttling protein nucleolin is a macrophage receptor for apoptotic cells.
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Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis
J Neuropathol Exp Neurol
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The 14-3-3 protein forms a molecular complex with heat shock protein Hsp60 and cellular prion protein
J Neuropathol Exp Neurol
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64(10):858-68
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Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex
Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex
Gastroenterology
2005
128(7):1919-36
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A novel mitochondrial C1-tetrahydrofolate synthetase is upregulated in human colon adenocarcinoma.
Biochem Biophys Res Commun
2004
315(1):204-11
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Ariyasu T, Matsumoto S, Kyono F, Hanaya T, Arai S, Ikeda M, Kurimoto M.
Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose.
In Vitro Cell. Dev. Biol. Anim.
2003
39:80-8
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JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation.
EMBO J
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Byoung-Hee Lee, Kumiko Yoshimatsu, Akihiko Maeda, Kazuhiko Ochiai, Masami Morimatsu, Koichi Araki, Michiko Ogino, Shigeru Morikawa, Jiro Arikawa
Association of the Nucleocapsid Protein of the Seoul and Hantaan Hantaviruses With Small Ubiquitin-Like modifier-1-related Molecules
Virus Res
2003
98 (1), 83-91
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Hiroyuki Oshiumi, Miwa Sasai, Kyoko Shida, Takashi Fujita, Misako Matsumoto, Tsukasa Seya
TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-Like Receptor 4 TICAM-1 That Induces Interferon-Beta
J Biol Chem
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278(50):49751-62
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Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkappaBalpha super-repressor
Cancer Sci
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Epitope-Tagged Metallothionein: Its Biochemical and Immunocytochemical Applications.
Journal of Health Science
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Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines
Biochem Biophys Res Commun
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300(3):669-73
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Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12
Bone
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31(2):303-12
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Irie N, Sakai N, Ueyama T, Kajimoto T, Shirai Y, Saito N.
Subtype- and species-specific knockdown of PKC using short interfering RNA
Biochem Biophys Res Commun
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Restoration of epithelial cell polarity in a colorectal cancer cell line by suppression of beta-catenin/T-cell factor 4-mediated gene transactivation
Cancer Res
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Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells
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Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways.
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The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2.
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