Cell No. : Cell Name RCB1433 : TEN  update : 2022/04/02
Comment			Human cell line derived from endometrial cancer. Clear cell carcinoma. Said c-erb-2(+), cathepsin D(+), CA125(+) in a part of cells.
Comment from the depositor
Terms and conditions			There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form			Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)
			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
	Basic information	Depositor	Izumi, Rikuichi
		Originator	Fushiki, Hiroshi
		Year of deposit	1998
		Animal	_human < Mammals
		Genus	Homo
		Species	sapiens
		Race	Japanese
		Gender	Female
		Age at sampling	74 years
		Tissue	endometrium
		Disease name	Endometrial cancer
		Metastatic ability	Yes
		Classification	cancer
		Year of origin	1993
		Lifespan	infinite
		Morphology	epithelial-like
		Cellosaurus(Expasy)	CVCL_E063
			deposit info	lot info
		Medium	Medium List
		Culture type		Adherent cells
		Culture medium		MEM + 10% FBS
		Antibiotics		Free
		Passage method		0.25% Trypsin
	Culture information	Passage ratio		1 : 4-8 split
		SC frequency		Subculture : once/week, Medium Renewal : 2 times/week
		Temperature		37 ℃
		CO2 concentration		5 %
		Freeze medium		Medium + 10% DMSO
		Freezing method		Slow freezing
		Mycoplasma		(-)
		Isozyme		LD, NP
		Chromosome mode		72-79(50) : 72(2), 73(6), 74(14), 75(12), 76(10)/
		STR(human)		OK
Images			deposit info	lot info
Reference information		Reference	1
		User's Publication	2

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Reference

2383  Fushiki H, Hidaka T, Fujimura M, Yasoshima K, Yamakawa Y, Izumi R  Characterization of a newly established human tumor cell line (TEN) from a patient with clear cell carcinoma of the uterine body and its sensitivity to anti-cancer agents.  Hum Cell  1997  10:199-208  PubMed ID: 9436040

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User's Publication

4359  Kogata Y, Tanaka T, Ono YJ, Hayashi M, Terai Y, Ohmichi M.  Foretinib (GSK1363089) induces p53-dependent apoptosis in endometrial cancer.  Oncotarget  2018  9(32):22769-22784  PubMed ID: 29854314   DOI: 10.18632/oncotarget.25232

14682  Tanaka T, Terai Y, Ashihara K, Fujiwara S, Tanaka Y, Sasaki H, Tsunetoh S, Ohmichi M.  The efficacy of the cyclin-dependent kinase 4/6 inhibitor in endometrial cancer  PLoS One  2017  12(5):e0177019  PubMed ID: 28472136   DOI: 10.1371/journal.pone.0177019