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RCB1189 : THP-1  update : 2018/07/31
CommentDifferentates to macrophage-like cells after treatment with phorbol ester. The variant subline (RCB2128 A-THP-1). Application consideration
Comment from the depositor
Restriction (Category)a
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor DSMZ
Year of deposit 1995
Animal human < Mammals
Genus Homo
Species sapiens
Gender Male
Age at sampling 1 year
Tissue peripheral blood
Case history acute monocytic leukemia
Classification cancer
History overseas, DMSZ (ACC16)
Lifespan infinite
Morphology lymphocyte-like
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 10 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Virus (HIV) LT 400
Virus (HTLV-1) (-)
Isozyme LD, NP
Chromosome mode 83-94(50) : /88(7), 89(3), 90(6), 91(8), 92(11)/
Images
deposit info
lot info
Reference information Reference 0
User's Publication 48


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Reference

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User's Publication
3393  Isse, Kumiko, Harada, Kenichi, Zen, Yoh, Kamihira, Takashi, Shimoda, Shinji, Harada, Mine, Nakanuma, Yasuni  Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts.  Hepatology  2005  41:506-16 
7231  Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S.  The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.  Nat. Immunol.  2015  16:1034-43  PubMed ID: 26322480
7239  Nagahama M, Seike S, Shirai H, Takagishi T, Kobayashi K, Takehara M, Sakurai J.  Role of P2X7 receptor in Clostridium perfringens beta-toxin-mediated cellular injury.  Biochim. Biophys. Acta  2015  1850:2159-67  PubMed ID: 26299247
7251  Yanagisawa K, Ogawa Y, Uchiumi H, Gohda F, Mawatari M, Ishizaki T, Mitsui T, Yokohama A, Handa H, Tsukamoto N, Nojima Y.  Gene polymorphisms of mannose-binding lectin confer susceptibility to Pneumocystis pneumonia in HIV-infected patients.  J. Infect. Chemother.  2015  21:769-75  PubMed ID: 26271591
7288  Inoue T, Ishikawa M, Sumiya Y, Kohda H, Inui T, Kuchiike D, Kubo K, Uto Y, Nishikata T.  Establishment of a Macrophage-activating Factor Assay System Using the Human Monocytic Cell Line THP-1.  Anticancer Res.  2015  35:4441-5  PubMed ID: 26168484
7316  Ito M, Shichita T, Okada M, Komine R, Noguchi Y, Yoshimura A, Morita R.  Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.  Nat Commun  2015  6:7360  PubMed ID: 26059659
7533  Jian Sun, Hiroko Shigemi, Yukie Tanaka, Takahiro Yamauchi, Takanori Ueda, Hiromichi Iwasaki  Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-κB signaling pathways.  Biochemistry and Biophysics Reports  2015  4:397-404 
7556  S Yoshimatsu, T Kato-Matsumaru, A Aono, K Chikamatsu, H Yamada, S Mitarai  Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads.  International Journal of Mycobacteriology  2015  4:245-249 
7638  Satoh J, Shimamura Y, Tabunoki H.  Gene expression profile of THP-1 monocytes following knockdown of DAP12, a causative gene for Nasu-Hakola disease.  Cell. Mol. Neurobiol.  2011  32:337-43  PubMed ID: 22080356
7695  Kanai Y, Hiroki S, Koshino H, Konoki K, Cho Y, Cayme M, Fukuyo Y, Yotsu-Yamashita M.  Identification of novel oxidized levuglandin D2 in marine red alga and mouse tissue.  J. Lipid Res.  2011  52:2245-54  PubMed ID: 21893678
7701  Oya K, Sakamoto N, Ohashi T, Sato M.  Combined stimulation with cyclic stretching and hypoxia increases production of matrix metalloproteinase-9 and cytokines by macrophages.  Biochem. Biophys. Res. Commun.  2011  412:678-82  PubMed ID: 21867689
7704  Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.  Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.  Atherosclerosis  2011  219:141-50  PubMed ID: 21862012
7813  Taira M, Shimoyama Y, Kagiya T, Sasaki M, Nezu T, Harada H, Kimura S.  Proteome analyses of human macrophages exposed to low cytotoxic IC90 copper (2+) ions.  Dent Mater J  2011  30:293-9  PubMed ID: 21597227
8120  Mizuno K, Toyoda Y, Fukami T, Nakajima M, Yokoi T.  Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.  Arch. Toxicol.  2010  85:199-207  PubMed ID: 20848085
8130  Mizuno K, Fukami T, Toyoda Y, Nakajima M, Yokoi T.  Terbinafine stimulates the pro-inflammatory responses in human monocytic THP-1 cells through an ERK signaling pathway.  Life Sci.  2010  87:537-44  PubMed ID: 20816994
8264  Yokoi H, Mizukami H, Nagatsu A, Tanabe H, Inoue M.  Hydroxy monounsaturated fatty acids as agonists for peroxisome proliferator-activated receptors.  Biol. Pharm. Bull.  2010  33:854-61  PubMed ID: 20460766
8393  Uto-Kondo H, Ayaori M, Ogura M, Nakaya K, Ito M, Suzuki A, Takiguchi S, Yakushiji E, Terao Y, Ozasa H, Hisada T, Sasaki M, Ohsuzu F, Ikewaki K.  Coffee consumption enhances high-density lipoprotein-mediated cholesterol efflux in macrophages.  Circ. Res.  2010  106:779-87  PubMed ID: 20075335
8402  Iizuka M, Tani M, Kishimoto Y, Saita E, Toyozaki M, Kondo K.  Inhibitory effects of balsamic vinegar on LDL oxidation and lipid accumulation in THP-1 macrophages.  J. Nutr. Sci. Vitaminol.  2010  56:421-7  PubMed ID: 21422711
8413  Lu X, Ohata K, Kondo Y, Espinoza JL, Qi Z, Nakao S.  Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis.  Cancer Sci.  2009  101:609-15  PubMed ID: 20028385
8456  Fujimoto A, Akifusa S, Kamio N, Hirofuji T, Nonaka K, Yamashita Y.  Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.  Free Radic. Res.  2009  44:128-34  PubMed ID: 19886750
8526  Taira M, Kagiya T, Harada H, Sasaki M, Kimura S, Narushima T, Nezu T, Araki Y.  Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.  J Mater Sci Mater Med  2009  21:267-75  PubMed ID: 19644653
8535  Watanabe T, Nishio H, Tanigawa T, Yamagami H, Okazaki H, Watanabe K, Tominaga K, Fujiwara Y, Oshitani N, Asahara T, Nomoto K, Higuchi K, Takeuchi K, Arakawa T.  Probiotic Lactobacillus casei strain Shirota prevents indomethacin-induced small intestinal injury: involvement of lactic acid.  Am. J. Physiol. Gastrointest. Liver Physiol.  2009  297:G506-13  PubMed ID: 19589943
8547  Hojo-Nakashima I, Sato R, Nakashima K, Hagiwara T, Yamada M.  Dynamic expression of peptidylarginine deiminase 2 in human monocytic leukaemia THP-1 cells during macrophage differentiation.  J. Biochem.  2009  146:471-9  PubMed ID: 19564157
8564  Ara T, Kurata K, Hirai K, Uchihashi T, Uematsu T, Imamura Y, Furusawa K, Kurihara S, Wang PL.  Human gingival fibroblasts are critical in sustaining inflammation in periodontal disease.  J. Periodont. Res.  2009  44:21-7  PubMed ID: 19515019
8579  Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M.  Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells.  J. Steroid Biochem. Mol. Biol.  2009  114:144-51  PubMed ID: 19429444
8604  Matsuki K, Tamasawa N, Yamashita M, Tanabe J, Murakami H, Matsui J, Imaizumi T, Satoh K, Suda T.  Metformin restores impaired HDL-mediated cholesterol efflux due to glycation.  Atherosclerosis  2009  206:434-8  PubMed ID: 19376519
8616  Miki Y, Itoh T, Hirano K, Eda S, Hayashi A, Yamanaka M, Beppu M.  Clearance of oxidatively damaged cells by macrophages: recognition of glycoprotein clusters by macrophage-surface nucleolin as early apoptotic cells.  Biol. Pharm. Bull.  2009  32:564-72  PubMed ID: 19336885
8700  Ishii S, Katsumura T, Shiozuka C, Ooyauchi K, Kawasaki K, Takigawa S, Fukushima T, Tokuji Y, Kinoshita M, Ohnishi M, Kawahara M, Ohba K.  Anti-inflammatory effect of buckwheat sprouts in lipopolysaccharide-activated human colon cancer cells and mice.  Biosci. Biotechnol. Biochem.  2008  72:3148-57  PubMed ID: 19060399
8818  Matsumoto E, Hatanaka M, Bohgaki M, Maeda S.  PKC pathway and ERK/MAPK pathway are required for induction of cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced differentiation of myeloleukemia cells.  Kobe J Med Sci  2007  52:181-94  PubMed ID: 17329956
8914  Hisakage Funabashi, Riko Matsuzawaa, Makiko Nakamura, Masayasu Mie and Eiry Kobatake  Bioluminescent enumeration of surface antigen-specific cells using the streptavidin?luciferase fusion protein  Sensors and Actuators B: Chemical  2006  120:51-56 
8953  Inamura J, Ikuta K, Jimbo J, Shindo M, Sato K, Torimoto Y, Kohgo Y.  Upregulation of hepcidin by interleukin-1beta in human hepatoma cell lines.  Hepatol. Res.  2005  33:198-205  PubMed ID: 16198622
9865  Seike S, Takehara M, Kobayashi K, Nagahama M.  Role of pannexin 1 in Clostridium perfringens beta-toxin-caused cell death.  Biochim. Biophys. Acta  2016  1858:3150-3156  PubMed ID: 27720686
9972  Uchida H, Hasegawa Y, Takahashi H, Makishima M.  1α-Dihydroxyvitamin D3 and Retinoic Acid Increase Nuclear Vitamin D Receptor Expression in Monocytic THP-1 Cells.  Anticancer Res.  2016  36:6297-6301  PubMed ID: 27919949
10181  Yoshino H, Kumai Y, Kashiwakura I.  Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages.  Mol Med Rep  2017  15:2867-2872  PubMed ID: 28447729
10592  Yamazoe H.  Multifunctional protein microparticles for medical applications.  Biomaterials  2018  155:1-12  PubMed ID: 29154040
11096  Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, Takihara Y, Sonoda Y.  A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells.  Nat Commun  2018    PubMed ID: 29875383
11176  Watanabe K, Suzuki H, Nishida T, Mishima M, Tachibana M, Fujishima M, Shimizu T, Watarai M.  Identification of novel Legionella genes required for endosymbiosis in Paramecium based on comparative genome analysis with Holospora spp.  FEMS Microbiol. Ecol.  2018    PubMed ID: 30124811
4052  Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N.  Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis  Nat Commun  2019  10:1072  PubMed ID: 30842549
11247  Zhitnyuk Y, Gee P, Lung MSY, Sasakawa N, Xu H, Saito H, Hotta A.  Efficient mRNA delivery system utilizing chimeric VSVG-L7Ae virus-like particles.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30316514
11288  Segawa S, Kondo Y, Nakai Y, Iizuka A, Kaneko S, Yokosawa M, Furuyama K, Tsuboi H, Goto D, Matsumoto I, Sumida T.  Placenta Specific 8 Suppresses IL-18 Production through Regulation of Autophagy and Is Associated with Adult Still Disease.  J. Immunol.  2018    PubMed ID: 30404814
4362  Nagai K, Domon H, Maekawa T, Oda M, Hiyoshi T, Tamura H, Yonezawa D, Arai Y, Yokoji M, Tabeta K, Habuka R, Saitoh A, Yamaguchi M, Kawabata S, Terao Y.  Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4.  Cell. Immunol.  2018    PubMed ID: 29366563
4363  Yoshino H, Konno H, Ogura K, Sato Y, Kashiwakura I.  Relationship between the Regulation of Caspase-8-Mediated Apoptosis and Radioresistance in Human THP-1-Derived Macrophages.  Int J Mol Sci  2018    PubMed ID: 30322167
4364  Mashiba R, Ishikawa M, Sumiya YU, Kawakatsu K, Tran NK, Nishikata T.  Phagocytic Activation of Macrophages with Serum MAF Depends on Engulfment Efficiency and Not Migratory Activity.  Anticancer Res.  2018    PubMed ID: 29970564
4365  Fukatsu H, Koide N, Tada-Oikawa S, Izuoka K, Ikegami A, Ichihara S, Ukaji T, Morita N, Naiki Y, Komatsu T, Umezawa K.  NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model.  Mol Med Rep  2018    PubMed ID: 30320338
4366  Komoda H, Shiraki A, Oyama JI, Nishikido T, Node K.  Azelnidipine Inhibits the Differentiation and Activation of THP-1 Macrophages through the L-Type Calcium Channel.  J. Atheroscler. Thromb.  2018    PubMed ID: 29398679
4506  Ebe H, Matsumoto I, Kawaguchi H, Kurata I, Tanaka Y, Inoue A, Kondo Y, Tsuboi H, Sumida T.  Clinical and functional significance of STEAP4-splice variant in CD14<sup>+</sup> monocytes in patients with rheumatoid arthritis.  Clin. Exp. Immunol.  2018  191(3):338-348  PubMed ID: 29080328
4507  Yoshida K, Nakashima A, Doi S, Ueno T, Okubo T, Kawano KI, Kanawa M, Kato Y, Higashi Y, Masaki T.  Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis.  Stem Cells Transl Med  2018  7(12):893-905  PubMed ID: 30269426
4520  Ken-ichiro Minato, Akihiro Ohara, and Masashi Mizuno  A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action  Mediators of Inflammation  2017  9 



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