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RCB1189 : THP-1  update : 2018/07/31
CommentDifferentates to macrophage-like cells after treatment with phorbol ester. The variant subline (RCB2128 A-THP-1). Application consideration
Comment from the depositor
Restriction (Category)a
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor DSMZ
Year of deposit 1995
Animal human < Mammals
Genus Homo
Species sapiens
Gender Male
Age at sampling 1 year
Tissue peripheral blood
Case history acute monocytic leukemia
Classification cancer
History overseas, DMSZ (ACC16)
Lifespan infinite
Morphology lymphocyte-like
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 10 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Virus (HIV) LT 400
Virus (HTLV-1) (-)
Isozyme LD, NP
Chromosome mode 83-94(50) : /88(7), 89(3), 90(6), 91(8), 92(11)/
Images
deposit info
lot info
Reference information Reference 0
User's Publication 40


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Reference

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User's Publication
Isse, Kumiko, Harada, Kenichi, Zen, Yoh, Kamihira, Takashi, Shimoda, Shinji, Harada, Mine, Nakanuma, Yasuni  Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts.  Hepatology  2005  41:506-16 
Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S.  The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.  Nat. Immunol.  2015  16:1034-43  PubMed ID: 26322480
Nagahama M, Seike S, Shirai H, Takagishi T, Kobayashi K, Takehara M, Sakurai J.  Role of P2X7 receptor in Clostridium perfringens beta-toxin-mediated cellular injury.  Biochim. Biophys. Acta  2015  1850:2159-67  PubMed ID: 26299247
Yanagisawa K, Ogawa Y, Uchiumi H, Gohda F, Mawatari M, Ishizaki T, Mitsui T, Yokohama A, Handa H, Tsukamoto N, Nojima Y.  Gene polymorphisms of mannose-binding lectin confer susceptibility to Pneumocystis pneumonia in HIV-infected patients.  J. Infect. Chemother.  2015  21:769-75  PubMed ID: 26271591
Inoue T, Ishikawa M, Sumiya Y, Kohda H, Inui T, Kuchiike D, Kubo K, Uto Y, Nishikata T.  Establishment of a Macrophage-activating Factor Assay System Using the Human Monocytic Cell Line THP-1.  Anticancer Res.  2015  35:4441-5  PubMed ID: 26168484
Ito M, Shichita T, Okada M, Komine R, Noguchi Y, Yoshimura A, Morita R.  Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.  Nat Commun  2015  6:7360  PubMed ID: 26059659
Jian Sun, Hiroko Shigemi, Yukie Tanaka, Takahiro Yamauchi, Takanori Ueda, Hiromichi Iwasaki  Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-κB signaling pathways.  Biochemistry and Biophysics Reports  2015  4:397-404 
S Yoshimatsu, T Kato-Matsumaru, A Aono, K Chikamatsu, H Yamada, S Mitarai  Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads.  International Journal of Mycobacteriology  2015  4:245-249 
Satoh J, Shimamura Y, Tabunoki H.  Gene expression profile of THP-1 monocytes following knockdown of DAP12, a causative gene for Nasu-Hakola disease.  Cell. Mol. Neurobiol.  2011  32:337-43  PubMed ID: 22080356
Kanai Y, Hiroki S, Koshino H, Konoki K, Cho Y, Cayme M, Fukuyo Y, Yotsu-Yamashita M.  Identification of novel oxidized levuglandin D2 in marine red alga and mouse tissue.  J. Lipid Res.  2011  52:2245-54  PubMed ID: 21893678
Oya K, Sakamoto N, Ohashi T, Sato M.  Combined stimulation with cyclic stretching and hypoxia increases production of matrix metalloproteinase-9 and cytokines by macrophages.  Biochem. Biophys. Res. Commun.  2011  412:678-82  PubMed ID: 21867689
Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.  Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.  Atherosclerosis  2011  219:141-50  PubMed ID: 21862012
Taira M, Shimoyama Y, Kagiya T, Sasaki M, Nezu T, Harada H, Kimura S.  Proteome analyses of human macrophages exposed to low cytotoxic IC90 copper (2+) ions.  Dent Mater J  2011  30:293-9  PubMed ID: 21597227
Mizuno K, Toyoda Y, Fukami T, Nakajima M, Yokoi T.  Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.  Arch. Toxicol.  2010  85:199-207  PubMed ID: 20848085
Mizuno K, Fukami T, Toyoda Y, Nakajima M, Yokoi T.  Terbinafine stimulates the pro-inflammatory responses in human monocytic THP-1 cells through an ERK signaling pathway.  Life Sci.  2010  87:537-44  PubMed ID: 20816994
Yokoi H, Mizukami H, Nagatsu A, Tanabe H, Inoue M.  Hydroxy monounsaturated fatty acids as agonists for peroxisome proliferator-activated receptors.  Biol. Pharm. Bull.  2010  33:854-61  PubMed ID: 20460766
Uto-Kondo H, Ayaori M, Ogura M, Nakaya K, Ito M, Suzuki A, Takiguchi S, Yakushiji E, Terao Y, Ozasa H, Hisada T, Sasaki M, Ohsuzu F, Ikewaki K.  Coffee consumption enhances high-density lipoprotein-mediated cholesterol efflux in macrophages.  Circ. Res.  2010  106:779-87  PubMed ID: 20075335
Iizuka M, Tani M, Kishimoto Y, Saita E, Toyozaki M, Kondo K.  Inhibitory effects of balsamic vinegar on LDL oxidation and lipid accumulation in THP-1 macrophages.  J. Nutr. Sci. Vitaminol.  2010  56:421-7  PubMed ID: 21422711
Lu X, Ohata K, Kondo Y, Espinoza JL, Qi Z, Nakao S.  Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis.  Cancer Sci.  2009  101:609-15  PubMed ID: 20028385
Fujimoto A, Akifusa S, Kamio N, Hirofuji T, Nonaka K, Yamashita Y.  Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.  Free Radic. Res.  2009  44:128-34  PubMed ID: 19886750
Taira M, Kagiya T, Harada H, Sasaki M, Kimura S, Narushima T, Nezu T, Araki Y.  Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.  J Mater Sci Mater Med  2009  21:267-75  PubMed ID: 19644653
Watanabe T, Nishio H, Tanigawa T, Yamagami H, Okazaki H, Watanabe K, Tominaga K, Fujiwara Y, Oshitani N, Asahara T, Nomoto K, Higuchi K, Takeuchi K, Arakawa T.  Probiotic Lactobacillus casei strain Shirota prevents indomethacin-induced small intestinal injury: involvement of lactic acid.  Am. J. Physiol. Gastrointest. Liver Physiol.  2009  297:G506-13  PubMed ID: 19589943
Hojo-Nakashima I, Sato R, Nakashima K, Hagiwara T, Yamada M.  Dynamic expression of peptidylarginine deiminase 2 in human monocytic leukaemia THP-1 cells during macrophage differentiation.  J. Biochem.  2009  146:471-9  PubMed ID: 19564157
Ara T, Kurata K, Hirai K, Uchihashi T, Uematsu T, Imamura Y, Furusawa K, Kurihara S, Wang PL.  Human gingival fibroblasts are critical in sustaining inflammation in periodontal disease.  J. Periodont. Res.  2009  44:21-7  PubMed ID: 19515019
Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M.  Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells.  J. Steroid Biochem. Mol. Biol.  2009  114:144-51  PubMed ID: 19429444
Matsuki K, Tamasawa N, Yamashita M, Tanabe J, Murakami H, Matsui J, Imaizumi T, Satoh K, Suda T.  Metformin restores impaired HDL-mediated cholesterol efflux due to glycation.  Atherosclerosis  2009  206:434-8  PubMed ID: 19376519
Miki Y, Itoh T, Hirano K, Eda S, Hayashi A, Yamanaka M, Beppu M.  Clearance of oxidatively damaged cells by macrophages: recognition of glycoprotein clusters by macrophage-surface nucleolin as early apoptotic cells.  Biol. Pharm. Bull.  2009  32:564-72  PubMed ID: 19336885
Ishii S, Katsumura T, Shiozuka C, Ooyauchi K, Kawasaki K, Takigawa S, Fukushima T, Tokuji Y, Kinoshita M, Ohnishi M, Kawahara M, Ohba K.  Anti-inflammatory effect of buckwheat sprouts in lipopolysaccharide-activated human colon cancer cells and mice.  Biosci. Biotechnol. Biochem.  2008  72:3148-57  PubMed ID: 19060399
Matsumoto E, Hatanaka M, Bohgaki M, Maeda S.  PKC pathway and ERK/MAPK pathway are required for induction of cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced differentiation of myeloleukemia cells.  Kobe J Med Sci  2007  52:181-94  PubMed ID: 17329956
Hisakage Funabashi, Riko Matsuzawaa, Makiko Nakamura, Masayasu Mie and Eiry Kobatake  Bioluminescent enumeration of surface antigen-specific cells using the streptavidin?luciferase fusion protein  Sensors and Actuators B: Chemical  2006  120:51-56 
Seike S, Takehara M, Kobayashi K, Nagahama M.  Role of pannexin 1 in Clostridium perfringens beta-toxin-caused cell death.  Biochim. Biophys. Acta  2016  1858:3150-3156  PubMed ID: 27720686
Uchida H, Hasegawa Y, Takahashi H, Makishima M.  1α-Dihydroxyvitamin D3 and Retinoic Acid Increase Nuclear Vitamin D Receptor Expression in Monocytic THP-1 Cells.  Anticancer Res.  2016  36:6297-6301  PubMed ID: 27919949
Yoshino H, Kumai Y, Kashiwakura I.  Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages.  Mol Med Rep  2017  15:2867-2872  PubMed ID: 28447729
Nakajima A, Sato H, Oda S, Yokoi T.  Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro.  Cell Biol. Toxicol.  2018  34:65-77  PubMed ID: 28285358
Yamazoe H.  Multifunctional protein microparticles for medical applications.  Biomaterials  2018  155:1-12  PubMed ID: 29154040
Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, Takihara Y, Sonoda Y.  A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells.  Nat Commun  2018    PubMed ID: 29875383
Watanabe K, Suzuki H, Nishida T, Mishima M, Tachibana M, Fujishima M, Shimizu T, Watarai M.  Identification of novel Legionella genes required for endosymbiosis in Paramecium based on comparative genome analysis with Holospora spp.  FEMS Microbiol. Ecol.  2018    PubMed ID: 30124811
Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N.  Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis  Nat Commun  2019  10:1072  PubMed ID: 30842549
Zhitnyuk Y, Gee P, Lung MSY, Sasakawa N, Xu H, Saito H, Hotta A.  Efficient mRNA delivery system utilizing chimeric VSVG-L7Ae virus-like particles.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30316514
Segawa S, Kondo Y, Nakai Y, Iizuka A, Kaneko S, Yokosawa M, Furuyama K, Tsuboi H, Goto D, Matsumoto I, Sumida T.  Placenta Specific 8 Suppresses IL-18 Production through Regulation of Autophagy and Is Associated with Adult Still Disease.  J. Immunol.  2018    PubMed ID: 30404814



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