| 利用者成果(英) |
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19508
Watanabe S, Takagi A, Yuba E, Kojima C, Dei N, Matsumoto A, Tanikawa J, Kawamura T, De Silva NH, Izawa T, Akazawa T, Kanegi R, Hatoya S, Inaba T, Sugiura K.
In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitum
FASEB J
2023
37(11):e23228
PubMed ID: 37815518
DOI: 10.1096/fj.202202036R
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21030
Hattori K, Takagi H, Ogata Y, Yamada T, Horiba H, Fukata K, Sakaida T, Yashiro Y, Hasegawa S, Tanaka H.
Immunostimulatory effects of a subcritical water extract of Ganoderma.
Biomed Rep
2023
PubMed ID: 36544853
DOI: 10.3892/br.2022.1583
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18101
Sugimoto C, Murakami Y, Ishii E, Fujita H, Wakao H.
Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity
Elife
2022
11:e70848
PubMed ID: 35379387
DOI: 10.7554/eLife.70848
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20556
Watanabe S, Yuba E, Akazawa T, Wijewardana V, Kakihara Y, Azuma A, Hagimori K, Kanegi R, Hatoya S, Inoue N, Inaba T, Sugiura K.
Potent adjuvant effect elicited for tumor immunotherapy by a liposome conjugated pH-sensitive polymer and dendritic cell-targeting Toll-like-receptor ligand.
Vaccine
2022
PubMed ID: 35131134
DOI: 10.1016/j.vaccine.2022.01.048
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6934
Baba K, Kuwada S, Nakao A, Li X, Okuda N, Nishida A, Mitsuda S, Fukuoka N, Kakeya H, Kataoka T.
Different localization of lysosomal-associated membrane protein 1 (LAMP1) in mammalian cultured cell lines.
Histochem Cell Biol
2020
PubMed ID: 31907597
DOI: 10.1007/s00418-019-01842-z
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13949
Wijesekera DPH, Yuba E, De Silva NH, Watanabe SI, Tsukamoto M, Ichida C, Izawa T, Itoh K, Kanegi R, Hatoya S, Yamate J, Inaba T, Sugiura K.
Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy
FASEB Bioadv
2020
2(1):5-17
PubMed ID: 32123853
DOI: 10.1096/fba.2019-00052
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4374
Une S, Nonaka K, Akiyama J.
Lectin Isolated from Japanese Red Sword Beans (Canavalia gladiata) as a Potential Cancer Chemopreventive Agent.
J. Food Sci.
2018
83(3):837-843
PubMed ID: 29437230
DOI: 10.1111/1750-3841.14057
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14549
Tsuji R, Ikado K, Fujiwara D.
Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production
Int J Mol Sci
2017
19(1):64
PubMed ID: 29278400
DOI: 10.3390/ijms19010064
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9804
Kiniwa T, Enomoto Y, Terazawa N, Omi A, Miyata N, Ishiwata K, Miyajima A.
NK cells activated by Interleukin-4 in cooperation with Interleukin-15 exhibit distinctive characteristics.
Proc. Natl. Acad. Sci. U.S.A.
2016
113:10139-44
PubMed ID: 27551096
DOI: 10.1073/pnas.1600112113
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12986
Romero-Pérez GA, Egashira M, Harada Y, Tsuruta T, Oda Y, Ueda F, Tsukahara T, Tsukamoto Y, Inoue R.
Orally Administered Salacia reticulata Extract Reduces H1N1 Influenza Clinical Symptoms in Murine Lung Tissues Putatively Due to Enhanced Natural Killer Cell Activity
Front Immunol
2016
7:115
PubMed ID: 27066007
DOI: 10.3389/fimmu.2016.00115
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15248
Kawahara T, Takahashi T, Oishi K, Tanaka H, Masuda M, Takahashi S, Takano M, Kawakami T, Fukushima K, Kanazawa H, Suzuki T.
Consecutive oral administration of Bifidobacterium longum MM-2 improves the defense system against influenza virus infection by enhancing natural killer cell activity in a murine model
Microbiol Immunol
2015
59(1):1-12
PubMed ID: 25400245
DOI: 10.1111/1348-0421.12210
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17089
Omi A, Enomoto Y, Kiniwa T, Miyata N, Miyajima A.
Mature resting Ly6C(high) natural killer cells can be reactivated by IL-15
Eur J Immunol
2014
44(9):2638-47
PubMed ID: 24995967
DOI: 10.1002/eji.201444570
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17114
Murata K, Abe Y, Futamura-Masudaa M, Uwaya A, Isami F, Matsuda H.
Activation of cell-mediated immunity by Morinda citrifolia fruit extract and its constituents
Nat Prod Commun
2014
9(4):445-50
PubMed ID: 24868850
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9095
N Meshii, G Takahashi, S Okunaga, M Hamada, S Iwai, A Takasu, Y Ogawa, Y Yura
Enhancement of Systemic Tumor Immunity for Squamous Cell Carcinoma Cells by an Oncolytic Herpes Simplex Virus
Cancer Gene Ther
2013
20 (9), 493-8
PubMed ID: 23887644
DOI: 10.1038/cgt.2013.45
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15341
Kovacs-Nolan J, Kanatani H, Nakamura A, Ibuki M, Mine Y.
β-1,4-mannobiose stimulates innate immune responses and induces TLR4-dependent activation of mouse macrophages but reduces severity of inflammation during endotoxemia in mice
J Nutr
2013
143(3):384-91
PubMed ID: 23343679
DOI: 10.3945/jn.112.167866
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18670
Yoshida N, Ino K, Ishida Y, Kajiyama H, Yamamoto E, Shibata K, Terauchi M, Nawa A, Akimoto H, Takikawa O, Isobe K, Kikkawa F.
Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model
Clin Cancer Res
2008
14(22):7251-9
PubMed ID: 19010841
DOI: 10.1158/1078-0432.CCR-08-0991
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18759
Kimura Y, Sumiyoshi M, Baba K.
Anti-tumor actions of major component 3'-O-acetylhamaudol of Angelica japonica roots through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation
Cancer Lett
2008
265(1):84-97
PubMed ID: 18358599
DOI: 10.1016/j.canlet.2008.02.009
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18763
Kimura Y, Sumiyoshi M, Suzuki T, Suzuki T, Sakanaka M.
Effects of water-soluble low-molecular-weight beta-1, 3-D-glucan (branch beta-1, 6) isolated from Aureobasidium pullulans 1A1 strain black yeast on restraint stress in mice
J Pharm Pharmacol
2007
59(8):1137-44
PubMed ID: 17725857
DOI: 10.1211/jpp.59.8.0012
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3329
Iinuma, Hisae, Okinaga, Kota, Fukushima, Ryoji, Inaba, Tsuyoshi, Iwasaki, Kota, Okinaga, Akira, Takahashi, Ichiro, Kaneko, Michio
Superior protective and therapeutic effects of IL-12 and IL-18 gene-transduced dendritic neuroblastoma fusion cells on liver metastasis of murine neuroblastoma.
J Immunol
2006
176:3461-9
PubMed ID: 16517714
DOI: 10.4049/jimmunol.176.6.3461
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3331
Ebata, Kazumi, Shimizu, Yukihiro, Nakayama, Yasuhiro, Minemura, Masami, Murakami, Jun, Kato, Tsutomu, Yasumura, Satoshi, Takahara, Terumi, Sugiyama, Toshiro, Saito, Shigeru
Immature NK cells suppress dendritic cell functions during the development of leukemia in a mouse model.
J Immunol
2006
176:4113-24
PubMed ID: 16547247
DOI: 10.4049/jimmunol.176.7.4113
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3169
Koga, Tomoaki, Harada, Hideki, Shi, Tea Seow, Okada, Seiji, Suico, Mary Ann, Shuto, Tsuyoshi, Kai, Hirofumi
Hyperthermia suppresses the cytotoxicity of NK cells via down-regulation of perforin/granzyme B expression.
Biochem Biophys Res Commun
2005
337:1319-23
PubMed ID: 16236268
DOI: 10.1016/j.bbrc.2005.09.184
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18760
Kimura Y, Sumiyoshi M.
Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice
J Ethnopharmacol
2004
95(2-3):447-53
PubMed ID: 15507373
DOI: 10.1016/j.jep.2004.08.027
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6153
Misawa E, Sakurai T, Yamada M, Tamura Y, Motoyoshi K.
Administration of macrophage colony-stimulating factor mobilized both CD11b+CD11c+ cells and NK1.1+ cells into peripheral blood.
Int Immunopharmacol
2004
4(6):791-803
PubMed ID: 15135320
DOI: 10.1016/j.intimp.2004.03.004
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17307
Peng Baogang, Liang Lijian, Liu Shuqin, Huang Jiefu, He Qiang, Lu Mingde, Leong Kam W, Ohno Tadao
Fixed-tumor vaccine: A practical formulation with cytokine-microspheres for protective and therapeutic antitumor immunity
The Chinese-German Journal of Clinical Oncology
2003
2:196-202
DOI: 10.1007/bf02835455
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2637
Kasahara M, Watanabe Y, Sumasu M, Nagata T
A family of MHC class I-like genes located in the vicinity of the mouse leukocyte receptor complex.
Proc Natl Acad Sci U S A
2002
99:13687-92
PubMed ID: 12370446
DOI: 10.1073/pnas.212375299
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4711
Tanji H, Yahata H, Hayamizu K, Shinozaki K, Okimoto T, Sakaguchi T, Asahara T.
Augmentation of local antitumor immunity in liver by interleukin-2 gene transfer via portal vein.
Cancer Gene Ther
2002
9(8):655-64
PubMed ID: 12136426
DOI: 10.1038/sj.cgt.7700483
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16911
Akasaki Y, Kikuchi T, Homma S, Abe T, Kofe D, Ohno T.
Antitumor effect of immunizations with fusions of dendritic and glioma cells in a mouse brain tumor model
J Immunother
2001
24(2):106-13.
PubMed ID: 11265767
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18801
Joki T, Kikuchi T, Akasaki Y, Saitoh S, Abe T, Ohno T.
Induction of effective antitumor immunity in a mouse brain tumor model using B7-1 (CD80) and intercellular adhesive molecule 1 (ICAM-1; CD54) transfection and recombinant interleukin 12
Int J Cancer
1999
82(5):714-20
PubMed ID: 10417770
DOI: 10.1002/(sici)1097-0215(19990827)82:5<714::aid-ijc15>3.0.co;2-q
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17885
Takahashi JA, Fukumoto M, Kozai Y, Ito N, Oda Y, Kikuchi H, Hatanaka M.
Induction of cytotoxic cell activities by a novel cyclic disulfide compound, SA3443 in vivo
Immunopharmacol Immunotoxicol
1991
13(1-2):121-33
PubMed ID: 1770215
DOI: 10.3109/08923979109019695
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