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RCB1126 : MC3T3-E1  update : 2018/07/06
CommentDifferentiate to osteoblasts. Collagen producing.
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC( regarding any kind of for-profit use.
Basic information Depositor Kodama, Hiroaki
Originator Kodama, Hiroaki
Year of deposit 1994
Original cell MC3T3-E1
Animal mouse < Mammals
Strain name C57BL/6
Gender Unknown
Age at sampling 0 day
Tissue newborn, calvaria
Classification other
Lifespan infinite
Morphology fibroblast-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM ALPHA + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 4 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP (mouse) OK
deposit info
lot info
Reference information Reference 9
User's Publication 331

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1848  Kodama,H., Amagai,Y., Sudo,H., Kasai,S. and Yamamoto,S.    Jpn J Oral Biol  1981  23:899-901 
2590  Yamaguchi A, Katagiri T, Ikeda T, Wozney, J M, Rosen V, Wang, E A, Kahn, A J, Suda T, Yoshiki S    J cell Biol  1991  113:681-687 
1992  Hiura K, Sumitani K, Kawata T, Higashino K, Okawa M, Sato T, Hakeda Y, Kumegawa M  Mouse osteoblastic cells (MC3T3-E1) at different stages of differentiation have opposite effects on osteoclastic cell formation.  Endocrinology  1991  128:1630-7 
1991  Hakeda Y, Nakatani Y, Hiramatsu M, Kurihara N, Tsunoi M, Ikeda E, Kumegawa M  Inductive effects of prostaglandins on alkaline phosphatase in osteoblastic cells, clone MC3T3-E1  J Biochem (Tokyo)  1985  97:97-104 
1849  Sudo H, Kodama, H A, Amagai Y, Yamamoto S, Kasai S    J Cell Biochem  1983  69:191-198 
1995  Zhou, H Y, Takita H, Fujisawa R, Mizuno M, Kuboki Y  Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells.  Calcif Tissue Int  1995  56:403-7 
1993  Kobayashi T, Sugimoto T, Saijoh K, Fukase M, Chihara K  Calcitonin directly acts on mouse osteoblastic MC3T3-E1 cells to stimulate mRNA expression of c-fos, insulin-like growth factor-1 and osteoblastic phenotypes (type 1 collagen and osteocalcin).  Biochem Biophys Res Commun  1994  199:876-80 
1994  Tsukamoto T, Matsui T, Takaishi T, Ito M, Fukase M, Chihara K  Retinoic acid differentially affects platelet-derived growth factor-regulated cell growth of mouse osteoblast-like cells  Cell Growth Differ  1994  5:207-212 
4575  Park E, Kim J, Kim MC, Yeo S, Kim J, Park S, Jo M, Choi CW, Jin HS, Lee SW, Li WY, Lee JW, Park JH, Huh D, Jeong SY.  Anti-Osteoporotic Effects of Kukoamine B Isolated from Lycii Radicis Cortex Extract on Osteoblast and Osteoclast Cells and Ovariectomized Osteoporosis Model Mice.  Int J Mol Sci  2019  20(11). pii: E2784  PubMed ID: 31174394

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User's Publication
3398  Ouyang, Xinshou, Fujimoto, Minoru, Nakagawa, Reiko, Serada, Satoshi, Tanaka, Toshio, Nomura, Shintaro, Kawase, Ichiro, Kishimoto, Tadamitsu, Naka, Tetsuji  SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells.  J Cell Physiol  2006  207:428-36  PubMed ID: 16419040
3348  Motokawa M, Kaku M, Tohma Y, Kawata T, Fujita T, Kohno S, Tsutsui K, Ohtani J, Tenjo K, Shigekawa M, Kamada H, Tanne K  Effects of cyclic tensile forces on the expression of vascular endothelial growth factor (VEGF) and macrophage-colony-stimulating factor (M-CSF) in murine osteoblastic MC3T3-E1 cells.  J Dent Res  2005  84:422-7  PubMed ID: 15840777
2356  Kato, H., Ypnezawa, T., Shirai, H., Sano, K., Abe, M.  An Improved Method for the Evaluation of the Effects of Laser Irradiation on Cultured Osteoblastic Cells  Bull Osaka Med Coll  1998  44:19-26 
3055  Arai M., Kinpara K., Takeuchi T., Tsuboi T., Togari A.  The release of alkaline phosphatase from osteoblastic cells stimulated by calcium ionophore A23187  Asia Pacific J of Pharmacology  2000  14:117-119 
3016  Adachi, T. et al  Effect of Actin Filament on Deformation-Induced Ca2+ Response in Osteoblast-Like Cells  JSME International Journal, Series C  2001  44:914-919 
2726  Inoue M, LeGeros RZ, Inoue M, Tsujigiwa H, Nagatsuka H, Yamamoto T, Nagai N  In vitro response of osteoblast-like and odontoblast-like cells to unsubstituted and substituted apatites  J Biomed Mater Res  2004  70A:585-593  PubMed ID: 15307163
2773  Sakiyama H, Nonaka T, Masuda R, Inoue N, Kuboki Y, Iijima M, Hirabayasi Y, Takahagi M, Yoshida K, Kuriiwa K, Yoshida M, Imajoh-Ohmi S  Characterization of mineral deposits formed in cultures of a hamster tartrate-resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) double-positive cell line (CCP).  Cell Tissue Res  2002  309:269-79  PubMed ID: 12172786
2870  Fukuyama R, Fujita T, Azuma Y, Hirano A, Nakamuta H, Koida M, Komori T  Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.  Biochem Biophys Res Commun  2004  315:636-42  PubMed ID: 14975748
2871  Notoya M, Otsuka E, Yamaguchi A, Hagiwara H  Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells.  Biochem Biophys Res Commun  2004  324:655-60  PubMed ID: 15474477
2897  Kim SW, Her SJ, Kim SY, Shin CS  Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts.  Biochem Biophys Res Commun  2005  327:811-9  PubMed ID: 15649418
2915  Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A  Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling.  J Biol Chem  2005  280:15842-8  PubMed ID: 15695512
3017  Adachi T, Sato K, Tomita Y  Directional dependence of osteoblastic calcium response to mechanical stimuli.  Biomech Model Mechanobiol  2003  2:73-82  PubMed ID: 14586810
3018  Sato K, Adachi T, Matsuo M, Tomita Y  Quantitative evaluation of threshold fiber strain that induces reorganization of cytoskeletal actin fiber structure in osteoblastic cells.  J Biomech  2005  38:1895-901  PubMed ID: 16023478
3049  Mogi M, Togari A  Activation of caspases is required for osteoblastic differentiation.  J Biol Chem  2003  278:47477-82  PubMed ID: 12954609
3051  Mogi M, Ozeki N, Nakamura H, Togari A  Dual roles for NF-kappaB activation in osteoblastic cells by serum deprivation: osteoblastic apoptosis and cell-cycle arrest.  Bone  2004  35:507-16 
3053  Kinpara K, Mogi M, Kuzushima M, Togari A, Kinpara K, Mogi M, Kuzushima M, Togari A, Kinpara K, Mogi M, Kuzushima M, Togari A  Osteoclast differentiation factor in human osteosarcoma cell line.  J Immunoassay  2000  21:327-40 
3069  Inoue H, Nishimura K, Oka D, Nakai Y, Shiba M, Tokizane T, Arai Y, Nakayama M, Shimizu K, Takaha N, Nonomura N, Okuyama A  Prostate cancer mediates osteoclastogenesis through two different pathways.  Cancer Lett  2005  223:121-8  PubMed ID: 15890244
3084  Kawate H, Wu Y, Ohnaka K, Nawata H, Takayanagi R  Tob proteins suppress steroid hormone receptor-mediated transcriptional activation.  Mol Cell Endocrinol  2005  230:77-86  PubMed ID: 15664454
2272  Fujishige K, Yanaka N, Akatsuka H, Omori K  Localization of clearance receptor in rat lung and trachea : association with chondrogenic differentiation  Am J Physiol  1998  274(3 Pt 1):425-431  PubMed ID: 9530179
3045  Yamamoto S, Mogi M, Kinpara K, Ishihara Y, Ueda N, Amano K, Nishihara T, Noguchi T, Togari A  Anti-proliferative capsular-like polysaccharide antigen from Actinobacillus actinomycetemcomitans induces apoptotic cell death in mouse osteoblastic MC3T3-E1 cells.  J Dent Res  1999  78:1230-7 
3046  Mogi M, Kinpara K, Kondo A, Togari A  Involvement of nitric oxide and biopterin in proinflammatory cytokine-induced apoptotic cell death in mouse osteoblastic cell line MC3T3-E1.  Biochem Pharmacol  1999  58:649-54 
2420  Yuhara S, Kasagi S, Inoue A, Otsuka E, Hirose S, Hagiwara H  Effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone.  Eur J Pharmacol  1999  383:387-93  PubMed ID: 10594333
3047  Mogi M, Kondo A, Kinpara K, Togari A  Anti-apoptotic action of nerve growth factor in mouse osteoblastic cell line.  Life Sci  2000  67:1197-206 
2480  Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S  Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development.  J Biol Chem  2001  276:3628-34  PubMed ID: 11071891
2487  Fujita T, Izumo N, Fukuyama R, Meguro T, Nakamuta H, Kohno T, Koida M  Phosphate provides an extracellular signal that drives nuclear export of Runx2/Cbfa1 in bone cells.  Biochem Biophys Res Commun  2001  280:348-52  PubMed ID: 11162521
2484  Taira M, Nakao H, Matsumoto T, Takahashi J  Cytotoxic effect of methyl methacrylate on 4 cultured fibroblasts.  Int J Prosthodont  2000  13:311-5  PubMed ID: 11203647
2557  Kusumi T, Nishi T, Tanaka M, Tsuchida S, Kudo H  A murine osteosarcoma cell line with a potential to develop ossification upon transplantation  Jpn J Cancer Res  2001  92:649-658  PubMed ID: 11429054
2771  Sakiyama H, Masuda R, Inoue N, Yamamoto K, Kuriiwa K, Nakagawa K, Yoshida K  Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers.  J Bone Miner Metab  2001  19:220-7  PubMed ID: 11448014
3048  Ozeki, Nobuaki, Mogi, Makio, Nakamura, Hiroshi, Togari, Akifumi  Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells.  Arch Oral Biol  2002  47:511-7  PubMed ID: 12208075
2822  Zhang, Gui Xia, Mizuno, Morimichi, Tsuji, Kiyomi, Tamura, Masato  Regulation of mRNA expression of matrix extracellular phosphoglycoprotein (MEPE)/ osteoblast/osteocyte factor 45 (OF45) by fibroblast growth factor 2 in cultures of rat bone marrow-derived osteoblastic cells.  Endocrine  2004  24:15-24  PubMed ID: 15249699
3407  Ito, Mikiko, Sakai, Yuko, Furumoto, Mari, Segawa, Hiroko, Haito, Sakiko, Yamanaka, Setsuko, Nakamura, Rie, Kuwahata, Masashi, Miyamoto, Ken-ichi  Vitamin D and phosphate regulate fibroblast growth factor-23 in K-562 cells.  Am J Physiol Endocrinol Metab  2005  288:E1101-9  PubMed ID: 15671080
2930  Keselowsky, Benjamin G, Collard, David M, Garcia, Andres J  Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation.  Proc Natl Acad Sci U S A  2005  102:5953-7  PubMed ID: 15827122
7091  M Azadi, A Teimouri, G Mehranzadeh  Preparation, characterization and biocompatible properties of β-chitin/silk fibroin/nanohydroxyapatite composite scaffolds prepared by freeze-drying method.  RSC Adv  2016  6:7048-7060 
7108  Demirta? TT, Goz E, Karakecili A, Gumu?derelio?lu M.  Combined delivery of PDGF-BB and BMP-6 for enhanced osteoblastic differentiation.  J Mater Sci Mater Med  2015  27:12  PubMed ID: 26676858
7118  Shirakawa J, Harada H, Noda M, Ezura Y.  PTH-Induced Osteoblast Proliferation Requires Upregulation of the Ubiquitin-Specific Peptidase 2 (Usp2) Expression.  Calcif. Tissue Int.  2015  98:306-15  PubMed ID: 26643174
7136  Valanezhad A, Odatsu T, Udoh K, Shiraishi T, Sawase T, Watanabe I.  Modification of resin modified glass ionomer cement by addition of bioactive glass nanoparticles.  J Mater Sci Mater Med  2015  27:3  PubMed ID: 26610926
7163  Nishide Y, Tousen Y, Tadaishi M, Inada M, Miyaura C, Kruger MC, Ishimi Y.  Combined Effects of Soy Isoflavones and β-Carotene on Osteoblast Differentiation.  Int J Environ Res Public Health  2015  12:13750-61  PubMed ID: 26516892
7164  Yoneshima E, Okamoto K, Sakai E, Nishishita K, Yoshida N, Tsukuba T.  The Transcription Factor EB (TFEB) Regulates Osteoblast Differentiation Through ATF4/CHOP-Dependent Pathway.  J. Cell. Physiol.  2015  231:1321-33  PubMed ID: 26519689
7178  Chen P, Nagai A, Tsutsumi Y, Ashida M, Doi H, Hanawa T.  Differences in the calcification of preosteoblast cultured on sputter-deposited titanium, zirconium, and gold.  J Biomed Mater Res A  2015  104:639-651  PubMed ID: 26488234
7211  Nakamoto T, Izu Y, Kawasaki M, Notomi T, Hayata T, Noda M, Ezura Y.  Mice Deficient in CIZ/NMP4 Develop an Attenuated Form of K/BxN-Serum Induced Arthritis.  J. Cell. Biochem.  2015  117:970-7  PubMed ID: 26378628
7220  Yang YJ, Tsou HK, Chen YH, Chung CJ, He JL.  Enhancement of bioactivity on medical polymer surface using high power impulse magnetron sputtered titanium dioxide film.  Mater Sci Eng C Mater Biol Appl  2015  57:58-66  PubMed ID: 26354240
7229  Inoue K, Imai Y.  Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation.  Biochim. Biophys. Acta  2015  1852:2432-41  PubMed ID: 26319416
7241  Noguchi T, Ebina K, Hirao M, Kawase R, Ohama T, Yamashita S, Morimoto T, Koizumi K, Kitaguchi K, Matsuoka H, Kaneshiro S, Yoshikawa H.  Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice.  Biochem. Biophys. Res. Commun.  2015  465:638-43  PubMed ID: 26297947
7282  Taniguchi Y, Kakura K, Yamamoto K, Kido H, Yamazaki J.  Accelerated Osteogenic Differentiation and Bone Formation on Zirconia with Surface Grooves Created with Fiber Laser Irradiation.  Clin Implant Dent Relat Res  2015  18:883-894  PubMed ID: 26179832
7290  Uchino K, Okamoto K, Sakai E, Yoneshima E, Iwatake M, Fukuma Y, Nishishita K, Tsukuba T.  Dual Effects of Liquiritigenin on the Proliferation of Bone Cells: Promotion of Osteoblast Differentiation and Inhibition of Osteoclast Differentiation.  Phytother Res  2015  29:1714-21  PubMed ID: 26172226
7302  Wang CH, Guo ZS, Pang F, Zhang LY, Yan M, Yan JH, Li KW, Li XJ, Li Y, Bi L, Han YS.  Effects of graphene modification on the bioactivation of polyethylene-terephthalate-based artificial ligaments.  ACS Appl Mater Interfaces  2015  7:15263-76  PubMed ID: 26111253
7307  Hatano M, Matsumoto Y, Fukushi J, Matsunobu T, Endo M, Okada S, Iura K, Kamura S, Fujiwara T, Iida K, Fujiwara Y, Nabeshima A, Yokoyama N, Fukushima S, Oda Y, Iwamoto Y.  Cadherin-11 regulates the metastasis of Ewing sarcoma cells to bone.  Clin. Exp. Metastasis  2015  32:579-91  PubMed ID: 26092671
7309  Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H.  Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.  PLoS ONE  2015  10:e0129704  PubMed ID: 26083413
7325  Tanaka K, Hirai T, Ishibashi Y, Izumo N, Togari A.  Modulation of osteoblast differentiation and bone mass by 5-HT2A receptor signaling in mice.  Eur. J. Pharmacol.  2015  762:150-7  PubMed ID: 26026645
7332  Gumu?derelio?lu M, Tuncay EO, Kaynak G, Demirta? TT, Ayd?n ST, Hakk? SS.  Encapsulated boron as an osteoinductive agent for bone scaffolds.  J Trace Elem Med Biol  2015  31:120-8  PubMed ID: 26004902
7338  Kaneshiro S, Otsuki D, Yoshida K, Yoshikawa H, Higuchi C.  MEK5 suppresses osteoblastic differentiation.  Biochem. Biophys. Res. Commun.  2015  463:241-7  PubMed ID: 25998381
7374  Yang D, Okamura H, Teramachi J, Haneji T.  Histone demethylase Utx regulates differentiation and mineralization in osteoblasts.  J. Cell. Biochem.  2015  116:2628-36  PubMed ID: 25920016
7431  Lin H, Gao X, Chen G, Sun J, Chu J, Jing K, Li P, Zeng R, Wei B.  Indole-3-carbinol as inhibitors of glucocorticoid-induced apoptosis in osteoblastic cells through blocking ROS-mediated Nrf2 pathway.  Biochem. Biophys. Res. Commun.  2015  460:422-7  PubMed ID: 25795137
7441  Terasawa K, Rajapakshe AR, Podyma-Inoue KA, Mishima-Tsumagari C, Yanagishita M, Hara-Yokoyama M.  Preferential recognition of isocitrate dehydrogenase by a rabbit monoclonal antibody (ab124797) against the C-terminal peptide of RANKL.  J. Immunol. Methods  2015  420:1-10  PubMed ID: 25771969
7444  Siddiqi MZ, Siddiqi MH, Kim YJ, Jin Y, Huq MA, Yang DC.  Effect of Fermented Red Ginseng Extract Enriched in Ginsenoside Rg3 on the Differentiation and Mineralization of Preosteoblastic MC3T3-E1 Cells.  J Med Food  2015  18:542-8  PubMed ID: 25764149
7445  Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H.  Chondroitin sulfate-E mediates estrogen-induced osteoanabolism.  Sci Rep  2015  5:8994  PubMed ID: 25759206
7455  Yamamura K, Miura T, Kou I, Muramatsu T, Furusawa M, Yoshinari M.  Influence of various superhydrophilic treatments of titanium on the initial attachment, proliferation, and differentiation of osteoblast-like cells.  Dent Mater J  2015  34:120-7  PubMed ID: 25748468
7480  Saito T, Teraoka K, Ota K.  Arrayed three-dimensional structures designed to induce and maintain a cell pattern by a topographical effect on cell behavior.  Mater Sci Eng C Mater Biol Appl  2015  49:256-61  PubMed ID: 25686947
7491  Okito A, Nakahama K, Akiyama M, Ono T, Morita I.  Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment.  Biochem. Biophys. Res. Commun.  2015  458:435-40  PubMed ID: 25668130
7519  Abbas Teimouri, Mohammad Azadi, Rahmatollah Emadi, Jalil Lari, Alireza Najafi Chermahini  Preparation, characterization, degradation and biocompatibility of different silk fibroin based composite scaffolds prepared by freeze-drying method for tissue engineering application.  Polym Degrad Stab  2015  121:18-29 
7531  Hsien-Te Chen, Hui-Ying Shu, Chi-Jen Chung, Ju-Liang He  Assessment of Bone Morphogenic Protein and Hydroxyapatite-Titanium Dioxide Composites for Bone Implant Materials.  Surface and Coatings Technology  2015  276:168-174 
7538  Katsuya SATO, Yuki OGAWA, Shin-ichi ITO, Shoichiro FUJISAWA, Kazuyuki MINAMI  Strain magnitude dependent intracellular calcium signaling response to uniaxial stretch in osteoblastic cells.  J Biomechanical Science and Engineering  2015  10:p.15-00242 
7541  L.T. Bang, S. Ramesha,. Purbolaksono, Y.C. Chinga, B.D. Long, Hari Chandran, S. Rameshc, R. Othmand  Effects of silicate and carbonate substitution on the properties of hydroxyapatite prepared by aqueous co-precipitation method.  Materials and Design  2015  87:788?796 
7543  M. Hirano, M. Yamane, N. Ohtsu  Surface characteristics and cell-adhesion performance of titanium treated with direct-current gas plasma comprising nitrogen and oxygen.  Appl Surf Sci.   2015  354:161-167 
7546  Megumi Fuse, Tohru Hayakawa, Tomomi Hashizume-Takizawa, Reiri Takeuchi, Tomoko Kurita-Ochiai, Junko Fujita-Yoshigaki, Masahiko Fukumoto  MC3T3-E1 Cell Assay on Collagen or Fibronectin Immobilized Poly (Lactic Acid-ε-Caprolactone) Film.  J Hard Tissue Biology  2015  24:249-256 
7549  Momoko Takahashi, Masaru Yamaguchi, Yasuhiro Tanimoto, Eriko Yao-Umezawa, Kazutaka Kasai  Biological Evaluation of a Prototype Material made of Polyglycolic Acid and Hydroxyapatite.  J Hard Tissue Biology  2015  24:375-384 
7551  Naofumi Ohtsu, Taro Kozuka, Mitsuhiro Hirano, Hirofumi Arai  Electrolyte effects on the surface chemistry and cellular response of anodized titanium.  Appl Surf Sci.   2015  349:911-915 
7561  Takaaki Arahira, Mitsugu Todo.  Effects of osteoblast-like cell seeding on the mechanical properties of porous composite scaffolds.  Advanced Composite Materials  2015  24:79-90 
7577  Yun Kee Jo, Bong-Hyuk Choi, Cong Zhou, Jin-Soo Ahn, Sang Ho Jun, Hyung Joon Cha  Bioengineered mussel glue incorporated with a cell recognition motif as an osteostimulating bone adhesive for titanium implants.  J Mater Chem B.  2015  3:8102-8114 
7582  Masuda E, Shirai K, Maekubo K, Hirai Y.  A newly established culture method highlights regulatory roles of retinoic acid on morphogenesis and calcification of mammalian limb cartilage.  BioTechniques  2014  58:318-24  PubMed ID: 26054768
7585  Aira Matsugaki, Gento Aramoto, Takayoshi Nakano  The alignment of MC3T3-E1 osteoblasts on steps of slip traces introduced by dislocation motion  Biomaterials  2012  33・30:7327-7335 
7586  Inaguma T, Han J, Isoda H.  Improvement of insulin resistance by Cyanidin 3-glucoside, anthocyanin from black beans through the up-regulation of GLUT4 gene expression.  BMC Proc  2012  5 Suppl 8:P21  PubMed ID: 22373152
7605  Odkhuu E, Koide N, Haque A, Tsolmongyn B, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.  Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine (PQQ).  Immunol. Lett.  2011  142:34-40  PubMed ID: 22193059
7624  Wei K, Li Y, Mugishima H, Teramoto A, Abe K.  Fabrication of core-sheath structured fibers for model drug release and tissue engineering by emulsion electrospinning.  Biotechnol J  2011  7:677-85  PubMed ID: 22125296
7630  Skrtic D, Antonucci JM.  Bioactive polymeric composites for tooth mineral regeneration: physicochemical and cellular aspects.  J Funct Biomater  2011  2:271-307  PubMed ID: 22102967
7634  Han SH, Kim KH, Han JS, Koo KT, Kim TI, Seol YJ, Lee YM, Ku Y, Rhyu IC.  Response of osteoblast-like cells cultured on zirconia to bone morphogenetic protein-2.  J Periodontal Implant Sci  2011  41:227-33  PubMed ID: 22087413
7640  Kim DY, Park YG, Quan HY, Kim SJ, Jung MS, Chung SH.  Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway.  Fitoterapia  2011  83:215-22  PubMed ID: 22061660
7649  Watanabe K, Tsunoda K, Itoh M, Fukui M, Mori H, Hitomi K.  Transglutaminase 2 and Factor XIII catalyze distinct substrates in differentiating osteoblastic cell line: utility of highly reactive substrate peptides.  Amino Acids  2011  44:209-14  PubMed ID: 22045386
7679  Takeuchi N, Machigashira M, Yamashita D, Shirakata Y, Kasuga T, Noguchi K, Ban S.  Cellular compatibility of a gamma-irradiated modified siloxane-poly(lactic acid)-calcium carbonate hybrid membrane for guided bone regeneration.  Dent Mater J  2011  30:730-8  PubMed ID: 21946495
7686  Choi EM.  Deoxyactein stimulates osteoblast function and inhibits bone-resorbing mediators in MC3T3-E1 cells.  J Appl Toxicol  2011  33:190-5  PubMed ID: 21910134
7693  Choi BH, Choi YS, Hwang DS, Cha HJ.  Facile surface functionalization with glycosaminoglycans by direct coating with mussel adhesive protein.  Tissue Eng Part C Methods  2011  18:71-9  PubMed ID: 21895565
7694  Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A.  1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.  J. Bone Miner. Res.  2011  26:2991-3000  PubMed ID: 21898591
7719  Takahata Y, Takarada T, Hinoi E, Nakamura Y, Fujita H, Yoneda Y.  Osteoblastic γ-aminobutyric acid, type B receptors negatively regulate osteoblastogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone.  J. Biol. Chem.  2011  286:32906-17  PubMed ID: 21828041
7744  Yoshida K, Higuchi C, Nakura A, Yoshikawa H.  Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα.  Biochem. Biophys. Res. Commun.  2011  411:774-9  PubMed ID: 21782794
7758  Ren G, Wang K, Chang R, Su Y, Wang J, Su J, Han B.  Simultaneous administration of fluoride and selenite regulates proliferation and apoptosis in murine osteoblast-like MC3T3-E1 cells by altering osteoprotegerin.  Biol Trace Elem Res  2011  144:1437-48  PubMed ID: 21739163
7773  Tsukasaki M, Yamada A, Suzuki D, Aizawa R, Miyazono A, Miyamoto Y, Suzawa T, Takami M, Yoshimura K, Morimura N, Yamamoto M, Kamijo R.  Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α.  Biochem. Biophys. Res. Commun.  2011  410:766-70  PubMed ID: 21689636
7774  Furugaki K, Moriya Y, Iwai T, Yorozu K, Yanagisawa M, Kondoh K, Fujimoto-Ohuchi K, Mori K.  Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292.  Clin. Exp. Metastasis  2011  28:649-59  PubMed ID: 21688034
7777  Okamura H, Yoshida K, Ochiai K, Haneji T.  Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.  Bone  2011  49:368-75  PubMed ID: 21683816
7790  Kataoka Y, Tamaki Y, Miyazaki T.  Synergistic responses of superficial chemistry and micro topography of titanium created by wire-type electric discharge machining.  Biomed Mater Eng  2011  21:113-21  PubMed ID: 21654067
7792  Zhang W, Wang H, Oyane A, Tsurushima H, Chu PK.  Osteoblast differentiation and disinfection induced by nitrogen plasma-treated surfaces.  Biomed Mater Eng  2011  21:75-82  PubMed ID: 21654064
7802  Tagaya M, Ikoma T, Takemura T, Hanagata N, Yoshioka T, Tanaka J.  Effect of interfacial proteins on osteoblast-like cell adhesion to hydroxyapatite nanocrystals.  Langmuir  2011  27:7645-53  PubMed ID: 21615097
7812  Tagaya M, Ikoma T, Takemura T, Hanagata N, Okuda M, Yoshioka T, Tanaka J.  Detection of interfacial phenomena with osteoblast-like cell adhesion on hydroxyapatite and oxidized polystyrene by the quartz crystal microbalance with dissipation.  Langmuir  2011  27:7635-44  PubMed ID: 21595447
7819  Yonezawa T, Lee JW, Hibino A, Asai M, Hojo H, Cha BY, Teruya T, Nagai K, Chung UI, Yagasaki K, Woo JT.  Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling.  Biochem. Biophys. Res. Commun.  2011  409:260-5  PubMed ID: 21570953
7827  Yonezawa T, Lee JW, Akazawa H, Inagaki M, Cha BY, Nagai K, Yagasaki K, Akihisa T, Woo JT.  Osteogenic activity of diphenyl ether-type cyclic diarylheptanoids derived from Acer nikoense.  Bioorg. Med. Chem. Lett.  2011  21:3248-51  PubMed ID: 21550801
7829  Shoji K, Tsubaki M, Yamazoe Y, Satou T, Itoh T, Kidera Y, Tanimori Y, Yanae M, Matsuda H, Taga A, Nakamura H, Nishida S.  Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells.  Arch. Pharm. Res.  2011  34:469-75  PubMed ID: 21547680
7834  Hagiwara K, Goto T, Araki M, Miyazaki H, Hagiwara H.  Olive polyphenol hydroxytyrosol prevents bone loss.  Eur. J. Pharmacol.  2011  662:78-84  PubMed ID: 21539839
7837  Kang KS, Lee SJ, Lee HS, Moon W, Cho DW.  Effects of combined mechanical stimulation on the proliferation and differentiation of pre-osteoblasts.  Exp. Mol. Med.  2011  43:367-73  PubMed ID: 21532314
7855  Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M.  Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells.  J. Biol. Chem.  2011  286:19138-48  PubMed ID: 21471203
7870  Wei K, Li Y, Kim KO, Nakagawa Y, Kim BS, Abe K, Chen GQ, Kim IS.  Fabrication of nano-hydroxyapatite on electrospun silk fibroin nanofiber and their effects in osteoblastic behavior.  J Biomed Mater Res A  2011  97:272-80  PubMed ID: 21442728
7885  Ma C, Zhang J, Fu J, Cheng L, Zhao G, Gu Y.  Up-regulation of VEGF by MC3T3-E1 cells treated with curculigoside.  Phytother Res  2011  25:922-6  PubMed ID: 21394809
7895  Fukuno N, Matsui H, Kanda Y, Suzuki O, Matsumoto K, Sasaki K, Kobayashi T, Tamura S.  TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts.  Biochem. Biophys. Res. Commun.  2011  408:202-7  PubMed ID: 21371434
7911  Tamaki Y, Lee WS, Kataoka Y, Miyazaki T.  A modified porous titanium sheet prepared by plasma-activated sintering for biomedical applications.  J Tissue Eng  2011  2010:425402  PubMed ID: 21350650
7916  Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, Kawaguchi H.  G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone.  J. Biol. Chem.  2011  286:13733-40  PubMed ID: 21345793
7926  Okada E, Yamanaka M, Ishikawa O.  New insights into the mechanism of abnormal calcification in nephrogenic systemic fibrosis - gadolinium promotes calcium deposition of mesenchymal stem cells and dermal fibroblasts.  J. Dermatol. Sci.  2011  62:58-63  PubMed ID: 21334857
7947  Uno K, Takarada T, Nakamura Y, Fujita H, Hinoi E, Yoneda Y.  A negative correlation between expression profiles of runt-related transcription factor-2 and cystine/glutamate antiporter xCT subunit in ovariectomized mouse bone.  J. Pharmacol. Sci.  2011  115:309-19  PubMed ID: 21325781
7950  Miura K, Yamada N, Hanada S, Jung TK, Itoi E.  The bone tissue compatibility of a new Ti-Nb-Sn alloy with a low Young's modulus.  Acta Biomater  2011  7:2320-6  PubMed ID: 21316491
7952  Kihara T, Ichikawa S, Yonezawa T, Lee JW, Akihisa T, Woo JT, Michi Y, Amagasa T, Yamaguchi A.  Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action.  Biochem. Biophys. Res. Commun.  2011  406:211-7  PubMed ID: 21303661
7954  Uno K, Takarada T, Takarada-Iemata M, Nakamura Y, Fujita H, Hinoi E, Yoneda Y.  Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit.  J. Cell. Physiol.  2011  226:2953-64  PubMed ID: 21302293
7969  Mikami Y, Senoo M, Lee M, Yamada K, Ochiai K, Honda MJ, Watanabe E, Watanabe N, Somei M, Takagi M.  Inhibitory effects of a tryptamine derivative on ultraviolet radiation-induced apoptosis in MC3T3-E1 mouse osteoblasts.  J. Pharmacol. Sci.  2011  115:214-20  PubMed ID: 21282935
7996  Kim BY, Yoon HY, Yun SI, Woo ER, Song NK, Kim HG, Jeong SY, Chung YS.  In vitro and in vivo inhibition of glucocorticoid-induced osteoporosis by the hexane extract of Poncirus trifoliata.  Phytother Res  2011  25:1000-10  PubMed ID: 21225901
8017  Lin J, Fan YJ, Mehl C, Zhu JJ, Chen H, Jin LY, Xu JH, Wang HM.  Eucommia ulmoides Oliv. antagonizes H2O2-induced rat osteoblastic MC3T3-E1 apoptosis by inhibiting expressions of caspases 3, 6, 7, and 9.  J Zhejiang Univ Sci B  2011  12:47-54  PubMed ID: 21194186
8029  Chatterjee K, Young MF, Simon CG Jr.  Fabricating gradient hydrogel scaffolds for 3D cell culture.  Comb. Chem. High Throughput Screen.  2010  14:227-36  PubMed ID: 21143178
8054  Chatterjee K, Sun L, Chow LC, Young MF, Simon CG Jr.  Combinatorial screening of osteoblast response to 3D calcium phosphate/poly(ε-caprolactone) scaffolds using gradients and arrays.  Biomaterials  2010  32:1361-9  PubMed ID: 21074846
8064  Lam WM, Pan HB, Fong MK, Cheung WS, Wong KL, Li ZY, Luk KD, Chan WK, Wong CT, Yang C, Lu WW.  In Vitro characterization of low modulus linoleic acid coated strontium-substituted hydroxyapatite containing PMMA bone cement.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2010  96:76-83  PubMed ID: 21053263
8072  Lee JW, Ahn G, Kim JY, Cho DW.  Evaluating cell proliferation based on internal pore size and 3D scaffold architecture fabricated using solid freeform fabrication technology.  J Mater Sci Mater Med  2010  21:3195-205  PubMed ID: 20981473
8082  Sun J, Ding Y, Lin NJ, Zhou J, Ro H, Soles CL, Cicerone MT, Lin-Gibson S.  Exploring cellular contact guidance using gradient nanogratings.  Biomacromolecules  2010  11:3067-72  PubMed ID: 20954734
8084  Nakura A, Higuchi C, Yoshida K, Yoshikawa H.  PKCα suppresses osteoblastic differentiation.  Bone  2010  48:476-84  PubMed ID: 20951242
8098  Zhang F, Tanaka H, Kawato T, Kitami S, Nakai K, Motohashi M, Suzuki N, Wang CL, Ochiai K, Isokawa K, Maeno M.  Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts.  Biochimie  2010  93:296-305  PubMed ID: 20937352
8099  Bae J, Goto S, Mie M, Kobatake E.  Construction of a thermostable cell adhesion protein for reverse transfection.  J. Biotechnol.  2010  150:447-51  PubMed ID: 20934468
8101  Lee JW, Kang KS, Lee SH, Kim JY, Lee BK, Cho DW.  Bone regeneration using a microstereolithography-produced customized poly(propylene fumarate)/diethyl fumarate photopolymer 3D scaffold incorporating BMP-2 loaded PLGA microspheres.  Biomaterials  2010  32:744-52  PubMed ID: 20933279
8105  Ahn G, Park JH, Kang T, Lee JW, Kang HW, Cho DW.  Effect of pore architecture on oxygen diffusion in 3D scaffolds for tissue engineering.  J Biomech Eng  2010  132:104506  PubMed ID: 20887024
8121  Hanagata N, Li X, Morita H, Takemura T, Li J, Minowa T.  Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice.  J. Bone Miner. Metab.  2010  29:279-90  PubMed ID: 20838829
8122  Choi BH, Choi YS, Kang DG, Kim BJ, Song YH, Cha HJ.  Cell behavior on extracellular matrix mimic materials based on mussel adhesive protein fused with functional peptides.  Biomaterials  2010  31:8980-8  PubMed ID: 20832110
8138  Rincon C, Chen CC, Meredith JC.  Effect of poly(3-octylthiophene) doping on the attachment and proliferation of osteoblasts.  Macromol Biosci  2010  10:1536-43  PubMed ID: 20803603
8146  Fukushima T, Ohno J, Hayakawa T, Imayoshi R, Kawaguchi M, Doi Y, Kanaya K, Mitarai M.  Polycationic protamine for water-insoluble complex formation with DNA.  Dent Mater J  2010  29:529-35  PubMed ID: 20733264
8154  Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M.  The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression.  Mol. Cell. Biol.  2010  30:4818-27  PubMed ID: 20713445
8165  Ding Y, Liang C, Yang SY, Ra JC, Choi EM, Kim JA, Kim YH.  Phenolic compounds from Artemisia iwayomogi and their effects on osteoblastic MC3T3-E1 cells.  Biol. Pharm. Bull.  2010  33:1448-53  PubMed ID: 20686247
8173  Fujimoto K, Kiyosaki T, Mitsui N, Mayahara K, Omasa S, Suzuki N, Shimizu N.  Low-intensity laser irradiation stimulates mineralization via increased BMPs in MC3T3-E1 cells.  Lasers Surg Med  2010  42:519-26  PubMed ID: 20662028
8178  Kiyosaki T, Mitsui N, Suzuki N, Shimizu N.  Low-level laser therapy stimulates mineralization via increased Runx2 expression and ERK phosphorylation in osteoblasts.  Photomed Laser Surg  2010  28 Suppl 1:S167-72  PubMed ID: 20649430
8192  Zhang F, Koyama Y, Sanuki R, Mitsui N, Suzuki N, Kimura A, Nakajima A, Shimizu N, Maeno M.  IL-17A stimulates the expression of inflammatory cytokines via celecoxib-blocked prostaglandin in MC3T3-E1 cells.  Arch. Oral Biol.  2010  55:679-88  PubMed ID: 20630498
8203  Cetin D, Kahraman AS, Gumu?derelio?lu M.  Novel scaffolds based on poly(2-hydroxyethyl methacrylate) superporous hydrogels for bone tissue engineering.  J Biomater Sci Polym Ed  2010  22:1157-78  PubMed ID: 20615330
8219  Itoh T, Takeda S, Akao Y.  MicroRNA-208 modulates BMP-2-stimulated mouse preosteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1.  J. Biol. Chem.  2010  285:27745-52  PubMed ID: 20576608
8225  Dhawan P, Christakos S.  Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the Vitamin D receptor in 24(OH)ase transcription.  J. Cell. Biochem.  2010  110:1314-23  PubMed ID: 20564225
8230  Yotsumoto N, Takeoka M, Yokoyama M.  Tail-suspended mice lacking calponin H1 experience decreased bone loss.  Tohoku J. Exp. Med.  2010  221:221-7  PubMed ID: 20551601
8247  Zhang F, Wang CL, Koyama Y, Mitsui N, Shionome C, Sanuki R, Suzuki N, Mayahara K, Shimizu N, Maeno M.  Compressive force stimulates the gene expression of IL-17s and their receptors in MC3T3-E1 cells.  Connect. Tissue Res.  2010  51:359-69  PubMed ID: 20497006
8248  Kishimoto K, Kato A, Osada S, Nishizuka M, Imagawa M.  Fad104, a positive regulator of adipogenesis, negatively regulates osteoblast differentiation.  Biochem. Biophys. Res. Commun.  2010  397:187-91  PubMed ID: 20493170
8285  Rico P, Gonzalez-Garcia C, Petrie TA, Garcia AJ, Salmeron-Sanchez M.  Molecular assembly and biological activity of a recombinant fragment of fibronectin (FNIII(7-10)) on poly(ethyl acrylate).  Colloids Surf B Biointerfaces  2010  78:310-6  PubMed ID: 20409696
8288  Takeda K, Takahashi NH, Yoshizawa M, Shibahara S.  Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes.  J. Biochem.  2010  148:139-48  PubMed ID: 20403807
8291  Hirai T, Kaneshige K, Kurosaki T, Nishio H.  Functional expression of 5-HT2A receptor in osteoblastic MC3T3-E1 cells.  Biochem. Biophys. Res. Commun.  2010  396:278-82  PubMed ID: 20399747
8304  Nakajima K, Komiyama Y, Hojo H, Ohba S, Yano F, Nishikawa N, Ihara S, Aburatani H, Takato T, Chung UI.  Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative.  Biochem. Biophys. Res. Commun.  2010  395:502-8  PubMed ID: 20382113
8306  Nagata M, Lonnerdal B.  Role of zinc in cellular zinc trafficking and mineralization in a murine osteoblast-like cell line.  J. Nutr. Biochem.  2010  22:172-8  PubMed ID: 20378322
8310  Arano T, Sato T, Matsuzaka K, Ikada Y, Yoshinari M.  Osteoblastic cell proliferation with uniform distribution in a large scaffold using radial-flow bioreactor.  Tissue Eng Part C Methods  2010  16:1387-98  PubMed ID: 20367244
8324  Kim BJ, Choi YS, Choi BH, Lim S, Song YH, Cha HJ.  Mussel adhesive protein fused with cell adhesion recognition motif triggers integrin-mediated adhesion and signaling for enhanced cell spreading, proliferation, and survival.  J Biomed Mater Res A  2010  94:886-92  PubMed ID: 20336754
8329  Usui Y, Uematsu T, Uchihashi T, Takahashi M, Takahashi M, Ishizuka M, Doto R, Tanaka H, Komazaki Y, Osawa M, Yamada K, Yamaoka M, Furusawa K.  Inorganic polyphosphate induces osteoblastic differentiation.  J. Dent. Res.  2010  89:504-9  PubMed ID: 20332330
8344  Oya K, Tanaka Y, Moriyama Y, Yoshioka Y, Kimura T, Tsutsumi Y, Doi H, Nomura N, Noda K, Kishida A, Hanawa T.  Differences in the bone differentiation properties of MC3T3-E1 cells on polished bulk and sputter-deposited titanium specimens.  J Biomed Mater Res A  2010  94:611-8  PubMed ID: 20198694
8348  Gonzalez-Garcia C, Sousa SR, Moratal D, Rico P, Salmeron-Sanchez M.  Effect of nanoscale topography on fibronectin adsorption, focal adhesion size and matrix organisation.  Colloids Surf B Biointerfaces  2010  77:181-90  PubMed ID: 20185279
8370  Fernandes H, Dechering K, van Someren E, Steeghs I, Apotheker M, Mentink A, van Blitterswijk C, de Boer J.  Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells.  Cells Tissues Organs (Print)  2010  191:443-52  PubMed ID: 20130390
8376  Yasuda Y, Tatematsu Y, Fujii S, Maeda H, Akamine A, Torabinejad M, Saito T.  Effect of MTAD on the differentiation of osteoblast-like cells.  J Endod  2010  36:260-3  PubMed ID: 20113785
8403  Kyung-Mi Chang, Eun-Mi Choi and Gun-Hee Kim  Chemical constituents of Chrysanthemum indicum L. flower oil and effect on osteoblastic MC3T3-E1 cells  Food Science and Biotechnology  2010  19:815-819 
8404  Yan Ding, Chun Liang, Huu Tung Nguyen, Eun Mi Choi, Jeong Ah Kim, and Young Ho Kim  Chemical Constituents from Acer mandshuricum and Their Effects on the Function of Osteoblastic MC3T3-E1 Cells  Bull. Korean Chem. Soc.  2010  31:929-933 
8408  Sailon AM, Allori AC, Davidson EH, Reformat DD, Allen RJ, Warren SM.  A novel flow-perfusion bioreactor supports 3D dynamic cell culture.  J. Biomed. Biotechnol.  2009  2009:873816  PubMed ID: 20037739
8410  Hsien-Te Chena, Ching-Hung Hsiaoa, Han-Yun Longa, Chi- Jen Chungc, Chih-Hsin Tangd, Keh-Chang Chena, Ju-Liang Hea  Micro-arc oxidation of β-titanium alloy: Structural characterization and osteoblast compatibility  Surface and Coatings Technology  2009  204:1126-1131 
8421  Rincon C, Meredith JC.  Osteoblast adhesion and proliferation on poly(3-octylthiophene) thin films.  Macromol Biosci  2009  10:258-64  PubMed ID: 20014196
8422  Sanuki R, Shionome C, Kuwabara A, Mitsui N, Koyama Y, Suzuki N, Zhang F, Shimizu N, Maeno M.  Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells.  Connect. Tissue Res.  2009  51:150-8  PubMed ID: 20001844
8428  Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y.  Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids.  J. Lipid Res.  2009  51:1010-6  PubMed ID: 19965598
8441  Kamon M, Zhao R, Sakamoto K.  Green tea polyphenol (-)-epigallocatechin gallate suppressed the differentiation of murine osteoblastic MC3T3-E1 cells.  Cell Biol. Int.  2009  34:109-16  PubMed ID: 19947947
8444  Hsi-Kai Tsoua, Ping- Yen Hsieha, Chi-Jen Chung, Chih-Hsin Tang, Tien-Wei Shyr, ju-LiangHe  Low-temperature deposition of anatase TiO2 on medical grade polyetheretherketone to assist osseous integration  Surface and Coatings Technology  2009  204:1121-1125 
8448  Moore NM, Lin NJ, Gallant ND, Becker ML.  The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation.  Biomaterials  2009  31:1604-11  PubMed ID: 19932505
8451  Takahashi S, Yamazoe H, Sassa F, Suzuki H, Fukuda J.  Preparation of coculture system with three extracellular matrices using capillary force lithography and layer-by-layer deposition.  J. Biosci. Bioeng.  2009  108:544-50  PubMed ID: 19914591
8454  Yang D, Yaguchi T, Lim CR, Ishizawa Y, Nakano T, Nishizaki T.  Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal.  Cancer Lett.  2009  291:225-9  PubMed ID: 19900759
8459  Obara M, Sakuma T, Fujikawa K.  The third type III module of human fibronectin mediates cell adhesion and migration.  J. Biochem.  2009  147:327-35  PubMed ID: 19880379
8473  Akman AC, Seda Ti?li R, Gumu?derelio?lu M, Nohutcu RM.  Bone morphogenetic protein-6-loaded chitosan scaffolds enhance the osteoblastic characteristics of MC3T3-E1 cells.  Artif Organs  2009  34:65-74  PubMed ID: 19821811
8481  Watanabe-Takano H, Takano K, Keduka E, Endo T.  M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation.  Exp. Cell Res.  2009  316:477-90  PubMed ID: 19800879
8483  LEE Seung-Jae, LEE In Hwan, PARK Jeong Hun, GWAK So-Jung, RHIE Jong-Won, CHO Dong-Woo, KO Tae Jo & KIM Dong Sung  Development of a hybrid scaffold and a bioreactor for cartilage regeneration  Chinese Science Bulletin  2009  54:3608-3612 
8498  Yamasaki K, Hagiwara H.  Excess iron inhibits osteoblast metabolism.  Toxicol. Lett.  2009  191:211-5  PubMed ID: 19735707
8501  Kasai T, Bandow K, Suzuki H, Chiba N, Kakimoto K, Ohnishi T, Kawamoto S, Nagaoka E, Matsuguchi T.  Osteoblast differentiation is functionally associated with decreased AMP kinase activity.  J. Cell. Physiol.  2009  221:740-9  PubMed ID: 19725053
8506  Hong Z, Mello A, Yoshida T, Luan L, Stern PH, Rossi A, Ellis DE, Ketterson JB.  Osteoblast proliferation on hydroxyapatite coated substrates prepared by right angle magnetron sputtering.  J Biomed Mater Res A  2009  93:878-85  PubMed ID: 19705463
8507  Yang JY, Jung JY, Cho SW, Choi HJ, Kim SW, Kim SY, Kim HJ, Jang CH, Lee MG, Han J, Shin CS.  Chloride intracellular channel 1 regulates osteoblast differentiation.  Bone  2009  45:1175-85  PubMed ID: 19703605
8508  Fernandes H, Dechering K, Van Someren E, Steeghs I, Apotheker M, Leusink A, Bank R, Janeczek K, Van Blitterswijk C, de Boer J.  The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells.  Tissue Eng Part A  2009  15:3857-67  PubMed ID: 19694522
8524  Akihisa Kamikawa, Ying Li, Yoshimitsu Abiko  Hydrogen Peroxide Reduced Osteomodulin Gene Expression in MC3T3-E1  J Hard Tissue Biology  2009  18:59-62 
8525  Mariona Rabionet, Jay Arre Toque, Ari Ide-Ektessabi  In vitro evaluation of osteoblast-like cells on hydroxyapatite-coated porous stainless steel implants by synchrotron radiation x-ray fluorescence  X-Ray Spectrometry  2009  38:278-282 
8538  Okamoto A, Ohnishi T, Bandow K, Kakimoto K, Chiba N, Maeda A, Fukunaga T, Miyawaki S, Matsuguchi T.  Reduction of orthodontic tooth movement by experimentally induced periodontal inflammation in mice.  Eur. J. Oral Sci.  2009  117:238-47  PubMed ID: 19583750
8565  Nagata A, Tanaka T, Minezawa A, Poyurovsky M, Mayama T, Suzuki S, Hashimoto N, Yoshida T, Suyama K, Miyata A, Hosokawa H, Nakayama T, Tatsuno I.  cAMP activation by PACAP/VIP stimulates IL-6 release and inhibits osteoblastic differentiation through VPAC2 receptor in osteoblastic MC3T3 cells.  J. Cell. Physiol.  2009  221:75-83  PubMed ID: 19496170
8572  Itoh T, Nozawa Y, Akao Y.  MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.  J. Biol. Chem.  2009  284:19272-9  PubMed ID: 19454767
8581  Maki M, Miyazaki H, Niisato N, Morihara T, Marunaka Y, Kubo T.  Blockers of K+/Cl- transporter/channels diminish proliferation of osteoblastic cells.  Biomed. Res.  2009  30:137-40  PubMed ID: 19420738
8587  Tung NH, Ding Y, Choi EM, Van Kiem P, Van Minh C, Kim YH.  New anthracene glycosides from Rhodomyrtus tomentosa stimulate osteoblastic differentiation of MC3T3-E1 cells.  Arch. Pharm. Res.  2009  32:515-20  PubMed ID: 19407968
8588  Nakao Y, Koike T, Ohta Y, Manaka T, Imai Y, Takaoka K.  Parathyroid hormone enhances bone morphogenetic protein activity by increasing intracellular 3', 5'-cyclic adenosine monophosphate accumulation in osteoblastic MC3T3-E1 cells.  Bone  2009  44:872-7  PubMed ID: 19442611
8618  Jin Woo Leea, GeunSeon Ahna, Dae Shick Kimb, Dong-Woo Cho  Development of nano- and microscale composite 3D scaffolds using PPF/DEF-HA and micro-stereolithography  Microelectronic Engineering  2009  86:1465-1467 
8628  Dorsey SM, Lin-Gibson S, Simon CG Jr.  X-ray microcomputed tomography for the measurement of cell adhesionand proliferation in polymer scaffolds.  Biomaterials  2009  30:2967-74  PubMed ID: 19286251
8629  Hou CH, Lin J, Huang SC, Hou SM, Tang CH.  Ultrasound stimulates NF-kappaB activation and iNOS expression via the Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts.  J. Cell. Physiol.  2009  220:196-203  PubMed ID: 19288477
8632  Kinugawa M, Fukuzawa S, Tachibana K.  Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine.  J. Bone Miner. Metab.  2009  27:303-14  PubMed ID: 19277454
8633  Nakamura M, Nagai A, Tanaka Y, Sekijima Y, Yamashita K.  Polarized hydroxyapatite promotes spread and motility of osteoblastic cells.  J Biomed Mater Res A  2009  92:783-90  PubMed ID: 19274714
8634  Raynor JE, Petrie TA, Fears KP, Latour RA, Garcia AJ, Collard DM.  Saccharide polymer brushes to control protein and cell adhesion to titanium.  Biomacromolecules  2009  10:748-55  PubMed ID: 19271753
8638  Cho SW, Yang JY, Sun HJ, Jung JY, Her SJ, Cho HY, Choi HJ, Kim SW, Kim SY, Shin CS.  Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells.  Bone  2009  44:1069-77  PubMed ID: 19254785
8645  Yuan Q, Kubo T, Doi K, Morita K, Takeshita R, Katoh S, Shiba T, Gong P, Akagawa Y.  Effect of combined application of bFGF and inorganic polyphosphate on bioactivities of osteoblasts and initial bone regeneration.  Acta Biomater  2009  5:1716-24  PubMed ID: 19251495
8649  Siddappa R, Mulder W, Steeghs I, van de Klundert C, Fernandes H, Liu J, Arends R, van Blitterswijk C, de Boer J.  cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models.  Tissue Eng Part A  2009  15:2135-43  PubMed ID: 19231969
8656  Wada Y, Mizuno M, Tamura M.  Enamel matrix derivative neutralized the effect of lipopolysaccharide on osteoprotegerin and receptor activator of nuclear factor kappa B ligand expression of osteoblasts.  Arch. Oral Biol.  2009  54:306-12  PubMed ID: 19201394
8662  Yoshida T, Clark MF, Stern PH.  The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival.  J. Cell. Biochem.  2009  106:896-902  PubMed ID: 19184980
8664  Lovmand J, Justesen J, Foss M, Lauridsen RH, Lovmand M, Modin C, Besenbacher F, Pedersen FS, Duch M.  The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization.  Biomaterials  2009  30:2015-22  PubMed ID: 19178942
8671  Tung NH, Ding Y, Choi EM, Minh CV, Kim YH.  New neolignan component from Camellia amplexicaulis and effects on osteoblast differentiation.  Chem. Pharm. Bull.  2009  57:65-8  PubMed ID: 19122318
8685  Tohru Hayakawa, Chihiro Mochizuki, Hiroki Hara, Tadao Fukushima, Fei Yang, Hong Shen, Shenguo Wang, Mitsunobu Sato  Influence of Apatite Crystallinity in Porous PLGA/Apatite Composite Scaffold on Cortical Bone Response  J Hard Tissue Biology  2009  18:7-12 
8686  Yasuhiro Tanimoto, Yo Shibata, Asuka Murakami, Takashi Miyazaki, Norihiro Nishiyama  Effect of Varying HAP/TCP Ratios in Tape-cast Biphasic Calcium Phosphate Ceramics on Response In Vitro  J Hard Tissue Biology  2009  18:71-76 
8692  Kim YH, Choi EM.  Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract.  Phytother Res  2008  23:737-9  PubMed ID: 19107859
8708  Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T.  JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation.  J. Bone Miner. Res.  2008  24:398-410  PubMed ID: 19016586
8714  Yamamichi N, Pugdee K, Chang WJ, Lee SY, Yoshinari M, Hayakawa T, Abiko Y.  Gene expression monitoring in osteoblasts on titanium coated with fibronectin-derived peptide.  Dent Mater J  2008  27:744-50  PubMed ID: 18972793
8724  Schulz RM, Wustneck N, van Donkelaar CC, Shelton JC, Bader A.  Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs.  Biotechnol. Bioeng.  2008  101:714-28  PubMed ID: 18814291
8727  Yamauchi M, Kawai S, Kato T, Ooshima T, Amano A.  Odd-skipped related 1 gene expression is regulated by Runx2 and Ikzf1 transcription factors.  Gene  2008  426:81-90  PubMed ID: 18804520
8734  Van Kiem P, Quang TH, Huong TT, Nhung le TH, Cuong NX, Van Minh C, Choi EM, Kim YH.  Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells.  Arch. Pharm. Res.  2008  31:823-9  PubMed ID: 18704321
8743  Cuong NX, Tuan TA, Kiem PV, Minh CV, Choi EM, Kim YH.  New cembranoid diterpenes from the Vietnamese soft coral Sarcophyton mililatensis stimulate osteoblastic differentiation in MC3T3-E1 cells.  Chem. Pharm. Bull.  2008  56:988-92  PubMed ID: 18591816
8766  Yamachika E, Tsujigiwa H, Shirasu N, Ueno T, Sakata Y, Fukunaga J, Mizukawa N, Yamada M, Sugahara T.  Immobilized recombinant human bone morphogenetic protein-2 enhances the phosphorylation of receptor-activated Smads.  J Biomed Mater Res A  2008  88:599-607  PubMed ID: 18314893
8779  Ohki TOMOMATSU, Akira TACHIBANA, Kiyoshi YAMAUCHI and Toshizumi TANABE  A film of collagen/calcium phosphate composite prepared by enzymatic mineralization in an aqueous phase  J The Ceramic Society of Japan  2008  116:10-13 
8785  Yen PH, Kiem PV, Nhiem NX, Tung NH, Quang TH, Minh CV, Kim JW, Choi EM, Kim YH.  A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells.  Arch. Pharm. Res.  2007  30:1179-85  PubMed ID: 18038896
8803  Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A.  Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation.  J. Bone Miner. Res.  2007  22:1362-72  PubMed ID: 17547533
8806  Wang J, Shang F, Jiang R, Liu L, Wang S, Hou J, Huan M, Mei Q.  Nitric oxide-donating genistein prodrug: design, synthesis, and bioactivity on MC3T3-E1 cells.  J. Pharmacol. Sci.  2007  104:82-9  PubMed ID: 17510526
8839  J.?E. Raynor, T.?A. Petrie, A.?J. Garcia, D.?M. Collard  Controlling Cell Adhesion to Titanium: Functionalization of Poly[oligo(ethylene glycol)methacrylate] Brushes with Cell-Adhesive Peptides  Adv Mater  2007  19:1724-1728 
8840  Jiepin Wang, Fujun Shang, Li Liu, Siwang wang, Jianbo Wang, Qibing Mei  In vivo and in vitro activity of genistein in osteoporosis  Indian J Pharmacol   2007  39:103-106 
8841  Ramakrishnaiah Siddappa, Winfried Mulder, Ilse Steeghs, Christine van de Klundert, Jun Liu, Roel Arends, Clemens van Blitterswijk and Jan de Boer  PKA signaling inhibits osteogenic differentiation and bone formation in rodent models  Cellular and Molecular Prerequisites for Bone Tissue Engineering  2007  :73-90 
8879  Hanagata N, Takemura T, Monkawa A, Ikoma T, Tanaka J.  Pre-adsorbed type-I collagen structure-dependent changes in osteoblastic phenotype.  Biochem. Biophys. Res. Commun.  2006  344:1234-40  PubMed ID: 16647688
8952  Lee KH, Choi EM.  Biochanin A stimulates osteoblastic differentiation and inhibits hydrogen peroxide-induced production of inflammatory mediators in MC3T3-E1 cells.  Biol. Pharm. Bull.  2005  28:1948-53  PubMed ID: 16204952
9012  Choi EM.  The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells.  Biochem. Pharmacol.  2005  70:363-8  PubMed ID: 15922308
9055  Kandler B, Maitz P, Fischer MB, Watzek G, Gruber R.  Platelets can neutralize hydrogen peroxide in an acute toxicity model with cells involved in granulation tissue formation.  Bone  2005  36:671-7  PubMed ID: 15784190
9329  Sogo Y. et al.  Zinc containing hydroxyapatite ceramics to promote osteoblastic cell activity.  Materials Schience and Technology  2004  20:1079-1083 
9389  Arai M., Nagasawa T., Tsunashima Y., Matsuda T., Kawamura H., Mogi M., Togari A.  A simple and useful method for evaluating biocompatibility of titanium alloy with heterotopic bone induced by demineralized bone matrix (DBM) pellet in mice.  Oral Therapeutics Pharmacology  2003  22:117-125 
9510  Ribeiro C, Correia V, Martins P, Gama FM, Lanceros-Mendez S.  Proving the suitability of magnetoelectric stimuli for tissue engineering applications.  Colloids Surf B Biointerfaces  2016  140:430-436  PubMed ID: 26797659
9521  Tanaka K, Hirai T, Kodama D, Kondo H, Hamamura K, Togari A.  α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts.  Br. J. Pharmacol.  2016  173:1058-69  PubMed ID: 26750808
9528  Ogawa K, Miyaji H, Kato A, Kosen Y, Momose T, Yoshida T, Nishida E, Miyata S, Murakami S, Takita H, Fugetsu B, Sugaya T, Kawanami M.  Periodontal tissue engineering by nano beta-tricalcium phosphate scaffold and fibroblast growth factor-2 in one-wall infrabony defects of dogs.  J. Periodont. Res.  2016  51:758-767  PubMed ID: 27870141
9565  Iwatsuki M, Matsuoka M.  Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells.  Toxicol. Mech. Methods  2016  26:132-8  PubMed ID: 26862884
9570  Yoo HY, Song YH, Foo M, Seo E, Hwang DS, Seo JH.  Recombinant mussel proximal thread matrix protein promotes osteoblast cell adhesion and proliferation.  BMC Biotechnol.  2016  16:16  PubMed ID: 26879700
9596  Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.  Anthraquinone Glycoside Aloin Induces Osteogenic Initiation of MC3T3-E1 Cells: Involvement of MAPK Mediated Wnt and Bmp Signaling.  Biomol Ther (Seoul)  2016  24:123-31  PubMed ID: 26869456
9597  Kumagai M, Mishima T, Watanabe A, Harada T, Yoshida I, Fujita K, Watai M, Tawata S, Nishikawa K, Morimoto Y.  5,6-Dehydrokawain from Alpinia zerumbet promotes osteoblastic MC3T3-E1 cell differentiation.  Biosci. Biotechnol. Biochem.  2016  80:1425-32  PubMed ID: 26940726
9626  Saito A, Yoshimura K, Miyamoto Y, Kaneko K, Chikazu D, Yamamoto M, Kamijo R.  Enhanced and suppressed mineralization by acetoacetate and β-hydroxybutyrate in osteoblast cultures.  Biochem. Biophys. Res. Commun.  2016  473:537-44  PubMed ID: 27018251
9655  Hase E, Matsubara O, Minamikawa T, Sato K, Yasui T.  In situ time-series monitoring of collagen fibers produced by standing-cultured osteoblasts using a second-harmonic-generation microscope.  Appl Opt  2016  55:3261-7  PubMed ID: 27140096
9689  Correia DM, Sencadas V, Ribeiro C, Martins PM, Martins P, Gama FM, Botelho G, Lanceros-Méndez S.  Processing and size range separation of pristine and magnetic poly(l-lactic acid) based microspheres for biomedical applications.  J Colloid Interface Sci  2016  476:79-86  PubMed ID: 27209393
9707  Zhang Q, Matsui H, Horiuchi H, Liang X, Sasaki K.  A-Raf and C-Raf differentially regulate mechanobiological response of osteoblasts to guide mechanical stress-induced differentiation.  Biochem. Biophys. Res. Commun.  2016  476:438-444  PubMed ID: 27240957
9716  Kitagawa M, Ando T, Subarnbhesaj A, Uchida T, Miyauchi M, Takata T.  N-terminal region of human ameloblastin synthetic peptide promotes bone formation.  Odontology  2017  105:116-121  PubMed ID: 27262724
9745  Kang S, Siddiqi MH, Yoon SJ, Ahn S, Noh HY, Kumar NS, Kim YJ, Yang DC.  Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study.  In Vitro Cell. Dev. Biol. Anim.  2016  52:895-905  PubMed ID: 27368432
9772  Sato M, Chen P, Tsutsumi Y, Shiota M, Hanawa T, Kasugai S.  Effect of strontium ions on calcification of preosteoblasts cultured on porous calcium- and phosphate-containing titanium oxide layers formed by micro-arc oxidation.  Dent Mater J  2016  35:627-34  PubMed ID: 27477229
9776  Rendina-Ruedy E, Graef JL, Lightfoot SA, Ritchey JW, Clarke SL, Lucas EA, Smith BJ.  Impaired glucose tolerance attenuates bone accrual by promoting the maturation of osteoblasts: Role of Beclin1-mediated autophagy.  Bone Rep  2016  5:199-207  PubMed ID: 28580387
9782  Chawalitpong S, Sornkaew N, Suksamrarn A, Palaga T.  Diarylheptanoid from Curcuma comosa Roxb. suppresses RANKL-induced osteoclast differentiation by decreasing NFATc1 and c-Fos expression via MAPK pathway.  Eur. J. Pharmacol.  2016  788:351-359  PubMed ID: 27523282
9825  Teimouri A, Azadi M, Shams Ghahfarokhi Z, Razavizadeh R.  Preparation and characterization of novel β-chitin/nanodiopside/nanohydroxyapatite composite scaffolds for tissue engineering applications.  J Biomater Sci Polym Ed  2017  28:1-14  PubMed ID: 27604099
9832  Yang D, Okamura H, Morimoto H, Teramachi J, Haneji T.  Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.  Lab. Invest.  2016  96:1050-62  PubMed ID: 27617401
9850  Park E, Kim MC, Choi CW, Kim J, Jin HS, Lee R, Lee JW, Park JH, Huh D, Jeong SY.  Effects of Dihydrophaseic Acid 3'-O-β-d-Glucopyranoside Isolated from Lycii radicis Cortex on Osteoblast Differentiation.  Molecules  2016  21:  PubMed ID: 27657033
9870  Takano-Yamamoto T, Fukunaga T, Takeshita N.  Gene Expression Analysis of CCN Protein in Bone Under Mechanical Stress.  Methods Mol. Biol.  2017  1489:283-308  PubMed ID: 27734385
9876  Kaynak Bayrak G, Demirtaş TT, Gümüşderelioğlu M.  Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds.  Carbohydr Polym  2017  157:803-813  PubMed ID: 27987994
9934  Kanazawa I, Tomita T, Miyazaki S, Ozawa E, Yamamoto LA, Sugimoto T.  Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells.  Calcif. Tissue Int.  2017  100:286-297  PubMed ID: 27832315
9942  Pawaputanon Na Mahasarakham C, Izu Y, Nishimori K, Izumi Y, Noda M, Ezura Y.  Lgr4 Expression in Osteoblastic Cells Is Suppressed by Hydrogen Peroxide Treatment.  J. Cell. Physiol.  2017  232:1761-1766  PubMed ID: 27861872
9951  Ode T, Podyma-Inoue KA, Terasawa K, Inokuchi JI, Kobayashi T, Watabe T, Izumi Y, Hara-Yokoyama M.  PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.  Exp. Cell Res.  2017  350:103-114  PubMed ID: 27865938
9960  Noguchi T, Ebina K, Hirao M, Morimoto T, Koizumi K, Kitaguchi K, Matsuoka H, Iwahashi T, Yoshikawa H.  Oxygen ultra-fine bubbles water administration prevents bone loss of glucocorticoid-induced osteoporosis in mice by suppressing osteoclast differentiation.  Osteoporos Int  2017  28:1063-1075  PubMed ID: 27896363
9976  Katsumura S, Izu Y, Yamada T, Griendling K, Harada K, Noda M, Ezura Y.  FGF Suppresses Poldip2 Expression in Osteoblasts.  J. Cell. Biochem.  2017  118:1670-1677  PubMed ID: 27918072
9994  Arahira T, Maruta M, Matsuya S.  Characterization and in vitro evaluation of biphasic α-tricalcium phosphate/β-tricalcium phosphate cement.  Mater Sci Eng C Mater Biol Appl  2017  74:478-484  PubMed ID: 28254321
10042  Tunçay EÖ, Demirtaş TT, Gümüşderelioğlu M.  Microwave-induced production of boron-doped HAp (B-HAp) and B-HAp coated composite scaffolds.  J Trace Elem Med Biol  2017  40:72-81  PubMed ID: 28159225
10058  Nagao M, Tanabe N, Manaka S, Naito M, Sekino J, Takayama T, Kawato T, Torigoe G, Kato S, Tsukune N, Maeno M, Suzuki N, Sato S.  LIPUS suppressed LPS-induced IL-1α through the inhibition of NF-κB nuclear translocation via AT1-PLCβ pathway in MC3T3-E1 cells.  J. Cell. Physiol.  2017  232:3337-3346  PubMed ID: 28063227
10068  Sato Y, Ishihara N, Nagayama D, Saiki A, Tatsuno I.  7-ketocholesterol induces apoptosis of MC3T3-E1 cells associated with reactive oxygen species generation, endoplasmic reticulum stress and caspase-3/7 dependent pathway.  Mol Genet Metab Rep  2017  10:56-60  PubMed ID: 28116245
10074  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646
10084  Kodama D, Hirai T, Kondo H, Hamamura K, Togari A.  Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system.  FEBS Lett.  2017  591:527-539  PubMed ID: 28094440
10139  Tsukune N, Naito M, Kubota T, Ozawa Y, Nagao M, Ohashi A, Sato S, Takahashi T.  Lamin A overexpression promotes osteoblast differentiation and calcification in the MC3T3-E1 preosteoblastic cell line.  Biochem. Biophys. Res. Commun.  2017  488:664-670  PubMed ID: 28237702
10140  Tanaka M, Sato Y, Haniu H, Nomura H, Kobayashi S, Takanashi S, Okamoto M, Takizawa T, Aoki K, Usui Y, Oishi A, Kato H, Saito N.  A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler.  PLoS ONE  2017  12:e0172601  PubMed ID: 28235026
10217  Kusuyama J, Bandow K, Ohnishi T, Hisadome M, Shima K, Semba I, Matsuguchi T.  Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low-molecular weight protein tyrosine phosphatase.  Mol. Biol. Cell  2017  28:1326-1336  PubMed ID: 28331074
10349  Sekiguchi Y, Mano H, Nakatani S, Shimizu J, Kataoka A, Ogura K, Kimira Y, Ebata M, Wada M.  Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation.  Mol Med Rep  2017  16:1328-1332  PubMed ID: 28627701
10352  Nathanael AJ, Oyane A, Nakamura M, Sakamaki I, Nishida E, Kanemoto Y, Miyaji H.  In Vitro and in Vivo Analysis of Mineralized Collagen-Based Sponges Prepared by a Plasma- and Precursor-Assisted Biomimetic Process.  ACS Appl Mater Interfaces  2017  9:22185-22194  PubMed ID: 28621514
10376  Nagao M, Tanabe N, Manaka S, Takayama T, Kawato T, Torigoe G, Sekino J, Tsukune N, Ozaki M, Maeno M, Suzuki N, Sato S.  Low-intensity pulsed ultrasound inhibits lipopolysaccharide-induced IL-6 and RANKL expression in osteoblasts.  J Oral Sci  2017  59:303-309  PubMed ID: 28637991
10405  Yahara M, Tei K, Tamura M.  Inhibition of neuropeptide Y Y1 receptor induces osteoblast differentiation in MC3T3‑E1 cells.  Mol Med Rep  2017  16:2779-2784  PubMed ID: 28656295
10429  Nakatsu Y, Nakagawa F, Higashi S, Ohsumi T, Shiiba S, Watanabe S, Takeuchi H.  Effect of acetaminophen on osteoblastic differentiation and migration of MC3T3-E1 cells.  Pharmacol Rep  2018  70:29-36  PubMed ID: 29306760
10441  Rodriguez R, Yoshimura K, Shibata Y, Miyamoto Y, Tanaka R, Uyama R, Sasa K, Suzuki D, Miyazaki T, Kamijo R.  Nanoindentation time-dependent deformation/recovery suggestive of methylglyoxal induced glycation in calcified nodules.  Nanomedicine  2017  13:2545-2553  PubMed ID: 28754466
10469  Matsuyama A, Higashi S, Tanizaki S, Morotomi T, Washio A, Ohsumi T, Kitamura C, Takeuchi H.  Celecoxib inhibits osteoblast differentiation independent of cyclooxygenase activity.  Clin. Exp. Pharmacol. Physiol.  2018  45:75-83  PubMed ID: 28815657
10502  Chen P, Miyake M, Tsukamoto M, Tsutsumi Y, Hanawa T.  Response of preosteoblasts to titanium with periodic micro/nanometer scale grooves produced by femtosecond laser irradiation.  J Biomed Mater Res A  2017  105:3456-3464  PubMed ID: 28879673
10528  Saiki A, Motoyoshi M, Motozawa K, Okamura T, Ueki K, Shimizu N, Asano M.  EMMPRIN Inhibits bFGF-Induced IL-6 Secretion in an Osteoblastic Cell Line, MC3T3-E1.  Int J Med Sci  2017  14:1173-1180  PubMed ID: 29104472
10542  Matsumoto K, Shimo T, Kurio N, Okui T, Ibaragi S, Kunisada Y, Obata K, Masui M, Pai P, Horikiri Y, Yamanaka N, Takigawa M, Sasaki A.  Low-intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling.  J. Cell. Biochem.  2018  119:4352-4360  PubMed ID: 28981158
10565  Torigoe G, Nagao M, Tanabe N, Manaka S, Kariya T, Kawato T, Sekino J, Kato S, Maeno M, Suzuki N, Shimizu N.  PYK2 mediates BzATP-induced extracellular matrix proteins synthesis.  Biochem. Biophys. Res. Commun.  2017  494:663-667  PubMed ID: 29061307
10643  Mikami R, Mizutani K, Aoki A, Tamura Y, Aoki K, Izumi Y.  Low-level ultrahigh-frequency and ultrashort-pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1.  Lasers Surg Med  2018  50:340-352  PubMed ID: 29214666
10657  Kawai S, Yamauchi M, Amano A.  Zinc-finger transcription factor Odd-skipped related 1 regulates cranial bone formation.  J. Bone Miner. Metab.  2018    PubMed ID: 29234951
10666  Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T.  Inhibition of adenosine monophosphate-activated protein kinase suppresses bone morphogenetic protein-2-induced mineralization of osteoblasts via Smad-independent mechanisms.  Endocr. J.  2018  65:291-298  PubMed ID: 29249772
10701  Kunimatsu R, Gunji H, Tsuka Y, Yoshimi Y, Awada T, Sumi K, Nakajima K, Kimura A, Hiraki T, Abe T, Naoto H, Yanoshita M, Tanimoto K.  Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts.  Lasers Med Sci  2018    PubMed ID: 29302842
10716  Kwon BJ, Seon GM, Lee MH, Koo MA, Kim MS, Kim D, Han JJ, Kim D, Kim J, Park JC.  Locally delivered ethyl-2,5-dihydroxybenzoate using 3D printed bone implant for promotion of bone regeneration in a osteoporotic animal model.  Eur Cell Mater  2018  35:1-12  PubMed ID: 29327779
10764  Takeda T, Tsubaki M, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S.  Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3.  Biomed. Pharmacother.  2018  100:486-494  PubMed ID: 29477912
10789  Yang DU, Siddiqi MH, Ahn S, Kang S, Noh HY, Yang DC.  In vitro evaluation of the potential therapeutic role of Dendropanax morbifera extract in ameliorating osteoporosis and resultant bone impairment using MC3T3-E1 cells.  In Vitro Cell. Dev. Biol. Anim.  2018  54:346-354  PubMed ID: 29560558
10802  Funaki Y, Hasegawa Y, Okazaki R, Yamasaki A, Sueda Y, Yamamoto A, Yanai M, Fukushima T, Harada T, Makino H, Shimizu E.  Resolvin E1 Inhibits Osteoclastogenesis and Bone Resorption by Suppressing IL-17-induced RANKL Expression in Osteoblasts and RANKL-induced Osteoclast Differentiation.  Yonago Acta Med  2018  61:8-18  PubMed ID: 29599617
10846  Fushimi S, Nohno T, Nagatsuka H, Katsuyama H.  Involvement of miR-140-3p in Wnt3a and TGFβ3 signaling pathways during osteoblast differentiation in MC3T3-E1 cells.  Genes Cells  2018    PubMed ID: 29740905
10848  Mohammad Azadi, Abbas Teimouri* and Ghasem Mehranzadeh   Preparation, characterization and biocompatible properties of β-chitin/silk fibroin/nanohydroxyapatite composite scaffolds prepared using a freeze-drying method  RSC Adv.  2016  6, 7048-7060 
10849  Junfeng WANG, Shukei SUGITA, Kazuaki NAGAYAMA, Takeo MATSUMOTO  Dynamics of actin filaments of MC3T3-E1 cells during adhesion process to substrate  Journal of Biomechanical Science and Engineering  2016  11:15-00637 
10860    Fabrication and in vitro characterization of electrospun poly (γ-glutamic acid)-silica hybrid scaffolds for bone regeneration  Polymer  2016  91,106-117 
10865    Functional peptide KP24 enhances submandibular gland tissue growth in vitro  Regenerative Therapy  2016  3, 108-113 
10872    β-Chitin/gelatin/nanohydroxyapatite composite scaffold prepared through freeze-drying method for tissue engineering applications  Polymer Bulletin  2016  73, 3513–3529 
10876    Advanced DLC coating technique on silicone-based tubular medical devices  Surface and Coatings Technology  2016  307, 1084-1087 
10897    Modification of Composite Resin Surface with Carbon Nanotubes Enhances Cell Proliferation  Nano Biomedicine  2016  8 
10898    Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor  Journal of Biomechanical Science and Engineering  2016  11, No.4, 2016 
10900    Cytocompatibility of Ti–6Al–7Nb through High-Pressure Torsion Processing  MATERIALS TRANSACTIONS  2016  57, 2020-2025 
10901    Cell Activity on Type 316L Stainless Steel with Self-Organized Nanopores Formed by Anodic Polarization  Journal of the Japan Institute of Metals and Materials  2018  82, 269-276 
10903    Surface chemistry and osteoblast-like cell response on a titanium surface modified by a focused Nd:YAG laser  Surface and Coatings Technology  2017  309, 220-226 
10909    Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications  Composites Part B: Engineering  2017  111, 37-44 
10918    Effects of a Chemically Synthesized Leucine-Rich Amelogenin Peptide (csLRAP) on Chondrogenic and Osteogenic Cells  Journal of Hard Tissue Biology  2017  26, 51- 60 
10920    Overexpression of RBP4 promotes proliferation, differentiation and mineralization of MC3T3-E1  Int J Clin Exp Pathol  2017  10:8092 
10928    Enhance the Bioactivity and Osseointegration of the Polyethylene-Terephthalate-Based Artificial Ligament via Poly(Dopamine) Coating with Mesoporous Bioactive Glass  Advanced Engineering Materials banner  2017  19 
10935    Antibacterial effect of nickel-titanium alloy owing to nickel ion release  Applied Surface Science  2017  405, 215-219 
10970    Evaluation of the enhancement of osteogenesis by Zn-releasing diamond-like carbon film  Diamond and Related Materials  2017  77, 131-136 
10982    Development of a Ta/TaN/TaNx(Ag)y/TaN nanocomposite coating system and bio-response study for biomedical applications  Vacuum  2017  145, 55-67 
10989    Effects of three-dimensional culture of mouse calvaria-derived osteoblastic cells in a collagen gel with a multichannel structure on the morphogenesis behaviors of engineered bone tissues  ACS Biomater. Sci. Eng.  2017  3 , 3414–3424 
10998    Antibacterial and cytotoxic effects of photoexcited Au clusters via blue high-power or white low-power lightemitting diode irradiation  Biology, Engineering and Medicine  2017  2:4 
11001    Anti-Osteoporotic Effects of Kukoamine B in Osteoblast and Osteoclast Cells and Ovariectomized Mice  Preprints  2017  2017100196 
11003    Influence of Strage in Water after Super-Hydrophilic Treatment of Titanium Surfaces on Osteroblast Behavor  Journal of Japanese Society of Oral Implantology  2017  30, 200-209 
11013    In Situ Observation and Measurement of Actin Stress Fiber Deformation in Stretched Osteoblast like Cell  Advances in Bioscience and Biotechnology,  2017  8, 421-433 
11034    A systematic study for optimal cell seeding and culture conditions in a perfusion mode bone-tissue bioreactor  Biochemical Engineering Journal  2018  132, 100-111 
11037    A Study of a Cell Mechanosensing System Under Mechanical Vibration Considering its Modes of Vibration and Calcium Ion Response  International Mechanical Engineering Congress and Exposition  2017  3 
11041    Ciona intestinalis calcitonin-like peptide promotes osteoblast differentiation and mineralization through MAPK pathway in MC3T3-E1 cells  Process Biochemistry  2018  67, 127-138 
11044    Attachment of Mouse Osteoblast-like Cells onto Fibronectin-or Albumin-immobilized Poly (Lactic Acid-ε-Caprolactone) Films  Journal of Oral Tissue Engineering  2017  15, 3-10 
11068    The Synergistic Effects of IL-6/IL-17A Promote Osteogenic Differentiation by Improving OPG/RANKL Ratio and Adhesion of MC3T3-E1 Cells on Hydroxyapatite  Journal of Cranio-Maxillofacial Surgery  2018  46,1361-1367  PubMed ID: 29805067
11077  Kato K, Morita K, Hirata I, Doi K, Kubo T, Kato K, Tsuga K.  Enhancement of calcification by osteoblasts cultured on hydroxyapatite surfaces with adsorbed inorganic polyphosphate.  In Vitro Cell. Dev. Biol. Anim.  2018    PubMed ID: 29766357
11129  Gonzalez-Garcia C, Cantini M, Ballester-Beltran J, Altankov G, Salmeron-Sanchez M.  The strength of the protein-material interaction determines cell fate.  Acta Biomater  2018    PubMed ID: 30006313
11146  Fujioka-Kobayashi M, Tsuru K, Nagai H, Fujisawa K, Kudoh T, Ohe G, Ishikawa K, Miyamoto Y.  Fabrication and evaluation of carbonate apatite-coated calcium carbonate bone substitutes for bone tissue engineering.  J Tissue Eng Regen Med  2018    PubMed ID: 30058260
11221  Khalid H, Suhaib F, Zahid S, Ahmed S, Jamal A, Kaleem M, Khan AS.  Microwave-assisted synthesis and in vitro osteogenic analysis of novel bioactive glass fibers for biomedical and dental applications.  Biomed Mater  2018    PubMed ID: 30251708
11232  Tsukune N, Naito M, Ohashi A, Ninomiya T, Sato S, Takahashi T.  Forced expression of mouse progerin attenuates the osteoblast differentiation interrupting β-catenin signal pathway in vitro.  Cell Tissue Res.  2018    PubMed ID: 30284086
11138  Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.  SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Nat Commun  2018    PubMed ID: 30026585
11254  Bai Y, Kanno T, Tatsumi H, Miyamoto K, Sha J, Hideshima K, Matsuzaki Y.  Feasibility of a Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/poly-d/l-lactide Composite as a Regenerative Biomaterial in Maxillofacial Surgery.  Materials (Basel)  2018    PubMed ID: 30347816
11258  Nguyen HT, Ono M, Oida Y, Hara ES, Komori T, Akiyama K, Nguyen HTT, Aung KT, Pham HT, Tosa I, Takarada T, Matsuo K, Mizoguchi T, Oohashi T, Kuboki T.  Bone Marrow Cells Inhibit BMP-2-Induced Osteoblast Activity in the Marrow Environment.  J. Bone Miner. Res.  2019    PubMed ID: 30352125
11265  Sato M, Asano T, Hosomichi J, Ono T, Nakata T.  Optogenetic manipulation of intracellular calcium by BACCS promotes differentiation of MC3T3-E1 cells.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30376992
11261  Marcotti S, Maki K, Reilly GC, Lacroix D, Adachi T.  Hyaluronic acid selective anchoring to the cytoskeleton: An atomic force microscopy study.  PLoS ONE  2018    PubMed ID: 30359403
11302  Baba TT, Terashima T, Oida S.  Liver-type of tissue non-specific alkaline phosphatase is induced during mouse bone and tooth cell differentiation.  Arch. Oral Biol.  2019    PubMed ID: 30439569
11267  Oyane A, Nakamura M, Sakamaki I, Shimizu Y, Miyata S, Miyaji H.  Laser-assisted wet coating of calcium phosphate for surface-functionalization of PEEK.  PLoS ONE  2018    PubMed ID: 30379904
11352  Choi H, Magyar CE, Nervina JM, Tetradis S.  Different duration of parathyroid hormone exposure distinctively regulates primary response genes Nurr1 and RANKL in osteoblasts.  PLoS ONE  2018    PubMed ID: 30576321
11486  Abdelrhman Y, Gepreel MA, Kobayashi S, Okano S, Okamoto T.  Biocompatibility of new low-cost (α + β)-type Ti-Mo-Fe alloys for long-term implantation.  Mater Sci Eng C Mater Biol Appl  2019    PubMed ID: 30889729
11445  Kuriya K, Nishio M, Wada S, Katsuzaki H, Nishise M, Okamoto H, Umekawa H.  Antiosteoporotic Effects of Acer palmatum Extract on Osteoclastogenesis and Osteoblastogenesis.  J Med Food  2019    PubMed ID: 30785809
11462  Sasaki JI, Kiba W, Abe GL, Katata C, Hashimoto M, Kitagawa H, Imazato S.  Fabrication of strontium-releasable inorganic cement by incorporation of bioactive glass.  Dent Mater  2019    PubMed ID: 30827799
11484  Kusuyama J, Amir MS, Albertson BG, Bandow K, Ohnishi T, Nakamura T, Noguchi K, Shima K, Semba I, Matsuguchi T.  JNK inactivation suppresses osteogenic differentiation, but robustly induces osteopontin expression in osteoblasts through the induction of inhibitor of DNA binding 4 (Id4).  FASEB J.  2019    PubMed ID: 30884976
11485  Nakamura K, Shirato M, Tenkumo T, Kanno T, Westerlund A, Örtengren U, Sasaki K, Niwano Y.  Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation.  Sci Rep  2019    PubMed ID: 30886168
4411  Yuka Yashima, View ORCID ProfileMasato Kaku, Taeko Yamamoto, Jin Izumino, Haruka Kagawa, Kotaro Tanimoto  Effect of continuous compressive force on the expression of RANKL, OPG, and VEGF in MC3T3-E1 and MLO-Y4 cells  bioRxiv  2018  19 
4412  Katsuya SATO, Manabu KATAYAMA, Shoichiro FUJISAWA, Tasuku NAKAHARA, Kazuyuki MINAMI  Evaluation of initiating characteristics of osteoblastic calcium signaling responses to stretch by video rate time-course observation  Journal of Biomechanical Science and Engineering  2018  13 
4413  Abbas Teimouri, Email author, Shahin Roohafza, Mohammad Azadi, Alireza Najafi Chermahini  Fabrication and characterization of chitosan/gelatin/nanodiopside composite scaffolds for tissue engineering application  Polymer Bulletin  2018  75:1487–1504 
4414    Visible light-induced antibacterial effects of the luminescent complex of hydroxyapatite and 8-hydroxyquinoline with gray titania coating  Applied Surface Science  2018  448, 529-538 
4416    Collagen-derived X-Hyp-Gly-type tripeptides promote differentiation of MC3T3-E1 pre-osteoblasts  Journal of Functional Foods  2018  46, 456-462 
4417    Improving Magnetoelectric Contactless Sensing and Actuation through Anisotropic Nanostructures  J. Phys. Chem.  2018  122:19189-9196 
4418    Effects of lactoferrin on dexamethasone-induced osteoporosis in mice  Take a look at the Recent articles  2018   
4419    Influence of estrogen deficiency on guided bone augmentation: investigation of rat calvarial model and osteoblast‐like MC3T3‐E1 cells  The European Journal of Oral Sciences  2018   
4281  Takahashi A, Mulati M, Saito M, Numata H, Kobayashi Y, Ochi H, Sato S, Kaldis P, Okawa A, Inose H.  Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone.  J. Biol. Chem.  2018    PubMed ID: 30366983
4282  Ando K, Imagama S, Kobayashi K, Ito K, Tsushima M, Morozumi M, Tanaka S, Machino M, Ota K, Nishida K, Nishida Y, Ishiguro N.  Effects of a self-assembling peptide as a scaffold on bone formation in a defect.  PLoS ONE  2018    PubMed ID: 29304115
4283  Kawamoto K, Miyaji H, Nishida E, Miyata S, Kato A, Tateyama A, Furihata T, Shitomi K, Iwanaga T, Sugaya T.  Characterization and evaluation of graphene oxide scaffold for periodontal wound healing of class II furcation defects in dog.  Int J Nanomedicine  2018    PubMed ID: 29713167
4489  iho Inoue, Mio Naritani, Resmi Raju, Mayu Miyagi, Masamitsu Oshima, Masahisa Inoue and Yoshizo Matsuka  Effect of Short-term Tumour Necrosis Factor-alpha (TNF-α)-stimulation on the Growth and Differentiation of MC3T3-E1 Osteoblast-like Cells  Journal of Hard Tissue Biology  2018  27:213-218 
4490  Kenichi Matsuzaka, Tadashi Horikawa, Eitoyo Kokubu and Takashi Inoue  Oral epithelial cells inhibit the proliferation, mRNA expressions of collagen type I, RUNX2 and BGP, and ALP activity of osteoblast-like cells in co-culture.  Biomedical Research  2018  29 (15):3085-3089 
4491  Graef JL, Rendina-Ruedy E, Crockett EK, Ouyang P, King JB, Cichewicz RH, Lucas EA, Smith BJ.  Select polyphenolic fractions from dried plum enhance osteoblast activity through BMP-2 signaling.  J. Nutr. Biochem.  2018  55:59-67  PubMed ID: 29413490
4493  Yoshihara C, Ueno T, Chen P, Tsutsumi Y, Hanawa T, Wakabayashi N.  Inverse response of osteoblasts and fibroblasts to growth on carbon-deposited titanium surfaces.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2018  106(5):1869-1877  PubMed ID: 28926194
4521  Drago Skrtic and Joseph M. Antonucci  Bioactive ACP-Based Polymeric Biocomposite  Biomaterials for Tissue Engineering  2017  4:90-142 
3158  Nishimura, Haruki, Nishimura, Masahiro, Oda, Ryo, Yamanaka, Katsuyuki, Matsubara, Takehiro, Ozaki, Yoshie, Sekiya, Kensuke, Hamada, Taizo, Kato, Yukio  Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds.  Exp Cell Res  2004  295:119-27  PubMed ID: 15051495

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