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細胞番号 : 細胞名
RCB0999 : MKN7  update : 2022/09/15
細胞特性(Comment:英)c-erbB-2 expressing gastric adenocarcinoma. Differentiated type.
細胞特性(日)日本人胃癌細胞株でc-erbB-2高発現株。Regan型アルカリフォスファタ ーゼを産生するという。高分化型管状腺癌由来。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Motoyama, Teiichi
樹立者 Hojo, Haruto
寄託日 1994
動物種 _human < Mammals
属名 Homo
種名 sapiens
人種 Japanese
性別 Male
39 years
採取組織 stomach, lymph node meta
転移 Yes
転移巣 lymph node
遺伝的特徴 Gastric adenocarcinoma
細胞分類 cancer
初代培養日 1975
入手歴 Hojo, Haruto - Motoyama, Teiichi
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_1417
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 RPMI1640 + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : once/week, Medium Renewal : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
ウィルス(HIV) (-)
アイソザイム検査 LD, NP
染色体検査 51-71(50) : /64(1),65(3),66(4),67(6),68(7),69(14)/
個体識別検査 OK
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 6件
Reference(日) 0件
利用者成果(英) 120件
利用者成果(日) 1件

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Reference(英)
4399  Homma N, Tamura G, Honda T, Matsumoto Y, Nishizuka S, Kawata S, Motoyama T.  Spreading of methylation within RUNX3 CpG island in gastric cancer.  Cancer Sci  2006  97(1):51-6  PubMed ID: 16367921   DOI: 10.1111/j.1349-7006.2005.00133.x
4501  Yanagawa N, Tamura G, Honda T, Endoh M, Nishizuka S, Motoyama T.  Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines.  Clin Cancer Res  2004  10(7):2447-51  PubMed ID: 15073123   DOI: 10.1158/1078-0432.ccr-03-0107
5050  Koyama K, Akiyama K, Kawahara H, Egashira A, Murakami H.  Alloimmunization with cultured human stomach cancer cell lines and the establishment of human-human hybridomas producing monoclonal antibodies.  Jpn J Cancer Res  1990  81(10):967-70  PubMed ID: 2121682   DOI: 10.1111/j.1349-7006.1990.tb03332.x
1889  Motoyama T, Hojo H, Watanabe H  Comparison of seven cell lines derived from human gastric carcinomas.  Acta Pathol Jpn  1986  36:65-83  PubMed ID: 3962675   DOI: 10.1111/j.1440-1827.1986.tb01461.x
5075  Nakatani H, Tahara E, Yoshida T, Sakamoto H, Suzuki T, Watanabe H, Sekiguchi M, Kaneko Y, Sakurai M, Terada M, et al.  Detection of amplified DNA sequences in gastric cancers by a DNA renaturation method in gel.  Jpn J Cancer Res  1986  77(9):849-53  PubMed ID: 3095279  
1861  Motoyama T, Watanabe H.  Carcinoembryonic antigen production in human gastric cancer cell lines in vitro and in nude mice.  Gan  1983  74(5):679-86  PubMed ID: 6642141  

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Reference(日)

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利用者成果(英)
21570  Shirasaka Y, Yamada K, Etoh T, Noguchi K, Hasegawa T, Ogawa K, Kobayashi T, Nishizono A, Inomata M.  Cytocidal Effect of Irradiation on Gastric Cancer Cells Infected with a Recombinant Mammalian Orthoreovirus Expressing a Membrane-Targeted KillerRed.  Pharmaceuticals (Basel)  2024  17(1)  PubMed ID: 38256912   DOI: 10.3390/ph17010079
19687  Mori Y, Nishikawa SG, Fratiloiu AR, Tsutsui M, Kataoka H, Joh T, Johnston RN.  Modulation of Reoviral Cytolysis (I): Combination Therapeutics  Viruses  2023  15(7):1472  PubMed ID: 37515160   DOI: 10.3390/v15071472
19939  hiozaki A, Fukami T, Shimizu H, Kosuga T, Kudou M, Takemoto K, Katsurahara K, Nishibeppu K, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Otsuji E.  Effects of TRPV2 on the Expression of PD-L1 and Its Binding Ability to PD-1 in Gastric Cancer  Ann Surg Oncol  2023  30(13):8704-8716  PubMed ID: 37599296   DOI: 10.1245/s10434-023-14084-0
19973  Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K.  Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer  Gastric Cancer  2023  26(6):878-890  PubMed ID: 37542528   DOI: 10.1007/s10120-023-01417-x
21486  Lou M, Iwatsuki M, Wu X, Zhang W, Matsumoto C, Baba H.  Cancer-Associated Fibroblast-Derived IL-8 Upregulates PD-L1 Expression in Gastric Cancer Through the NF-κB Pathway.  Ann Surg Oncol  2023    PubMed ID: 38006530   DOI: 10.1245/s10434-023-14586-x
17567  Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Kamiya H, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.  Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer  Cancer Sci  2022  113(6):1984-1998  PubMed ID: 35307915   DOI: 10.1111/cas.15342
20459  Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.  Ann Surg Oncol  2022    PubMed ID: 34855064   DOI: 10.1245/s10434-021-11132-5
20571  Fu L, Yonemura A, Yasuda-Yoshihara N, Umemoto T, Zhang J, Yasuda T, Uchihara T, Akiyama T, Kitamura F, Yamashita K, Okamoto Y, Bu L, Wei F, Hu X, Liu Y, Ajani JA, Tan P, Baba H, Ishimoto T.  Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer.  Gastric Cancer  2022    PubMed ID: 35166958   DOI: 10.1007/s10120-022-01283-z
20622  Takaki W, Konishi H, Matsubara D, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Kubota T, Okamoto K, Otsuji E.  Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.  Int J Mol Sci  2022  23(6)  PubMed ID: 35328684   DOI: 10.3390/ijms23063264
20627  Soda T, Gen Y, Terasaki K, Iwai N, Kitaichi T, Dohi O, Taketani H, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y, Yasui K.  Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach.  Sci Rep  2022  12(1):5050  PubMed ID: 35322078   DOI: 10.1038/s41598-022-08904-8
20661  Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  Functions and Clinical Significance of CACNA2D1 in Gastric Cancer.  Ann Surg Oncol  2022    PubMed ID: 35445337   DOI: 10.1245/s10434-022-11752-5
13323  Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.  TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer.  J Cancer  2021    PubMed ID: 33391428   DOI: 10.7150/jca.47577
20005  Iwata Y, Yasufuku I, Saigo C, Kito Y, Takeuchi T, Yoshida K.  Anti-fibrotic properties of an adiponectin paralog protein, C1q/TNF-related protein 6 (CTRP6), in diffuse gastric adenocarcinoma.  J Cancer  2021  12(4):1161-1168  PubMed ID: 33442414   DOI: 10.7150/jca.46765
20116  Kurashima K, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.  Gastric Cancer  2021    PubMed ID: 33864161   DOI: 10.1007/s10120-021-01187-4
14345  Katsurahara K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  ANO9 regulates PD-L2 expression and binding ability to PD-1 in gastric cancer  Cancer Sci  2021  112(3):1026-1037.   PubMed ID: 33404124   DOI: 10.1111/cas.14796
16126  Nakamura K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  The expression of the alpha1 subunit of Na +/K +-ATPase is related to tumor development and clinical outcomes in gastric cancer  Gastric Cancer  2021  24(6):1278-1292  PubMed ID: 34251542   DOI: 10.1007/s10120-021-01212-6
16229  Wenzhe Li, Atsushi Okabe, Genki Usui, Masaki Fukuyo, Keisuke Matsusaka, Bahityar Rahmutulla, Yasunobu Mano, Takayuki Hoshii, Sayaka Funata, Nobuhiro Hiura, Masashi Fukayama, Patrick Tan, Tetsuo Ushiku, Atsushi Kaneda  Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer  Cancer Sci  2021  112(8):3349-3362  PubMed ID: 34014591   DOI: 10.1111/cas.14978
16861  Kunzke T, Hölzl FT, Prade VM, Buck A, Huber K, Feuchtinger A, Ebert K, Zwingenberger G, Geffers R, Hauck SM, Haffner I, Luber B, Lordick F, Walch A.  Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer  Clin Transl Med  2021  11(9):e547.  PubMed ID: 34586736   DOI: 10.1002/ctm2.547
12041  Hirano T, Shinsato Y, Tanabe K, Higa N, Kamil M, Kawahara K, Yamamoto M, Minami K, Shimokawa M, Arigami T, Yanagita S, Matushita D, Uenosono Y, Ishigami S, Kijima Y, Maemura K, Kitazono I, Tanimoto A, Furukawa T, Natsugoe S.  FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer.  Oncogenesis  2020    PubMed ID: 32029704   DOI: 10.1038/s41389-020-0190-7
13023  Berlamont H, De Witte C, Bauwens E, Min Jou H, Ducatelle R, De Meester E, Gansemans Y, Deforce D, Van Nieuwerburgh F, Haesebrouck F, Smet A.  Distinct transcriptome signatures of Helicobacter suis and Helicobacter heilmannii strains upon adherence to human gastric epithelial cells.  Vet Res  2020    PubMed ID: 32381076   DOI: 10.1186/s13567-020-00786-w
13131  Okabe A, Huang KK, Matsusaka K, Fukuyo M, Xing M, Ong X, Hoshii T, Usui G, Seki M, Mano Y, Rahmutulla B, Kanda T, Suzuki T, Rha SY, Ushiku T, Fukayama M, Tan P, Kaneda A.  Cross-species chromatin interactions drive transcriptional rewiring in Epstein-Barr virus-positive gastric adenocarcinoma.  Nat Genet  2020    PubMed ID: 32719515   DOI: 10.1038/s41588-020-0665-7
13315  Ebert K, Zwingenberger G, Barbaria E, Keller S, Heck C, Arnold R, Hollerieth V, Mattes J, Geffers R, Raimúndez E, Hasenauer J, Luber B.  Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines.  BMC Cancer  2020    PubMed ID: 33115415   DOI: 10.1186/s12885-020-07540-7
13344  Hinata M, Kunita A, Abe H, Morishita Y, Sakuma K, Yamashita H, Seto Y, Ushiku T, Fukayama M.  Exosomes of Epstein-Barr Virus-Associated Gastric Carcinoma Suppress Dendritic Cell Maturation.  Microorganisms  2020    PubMed ID: 33198173   DOI: 10.3390/microorganisms8111776
13504  Baatar S, Bai T, Yokobori T, Gombodorj N, Nakazawa N, Ubukata Y, Kimura A, Kogure N, Sano A, Sohda M, Sakai M, Tumenjargal A, Ogata K, Kuwano H, Shirabe K, Saeki H.  High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer  Ann Surg Oncol  2020  27(11):4360-4368  PubMed ID: 32356270   DOI: 10.1245/s10434-020-08518-2
13525  Asakawa Y, Okabe A, Fukuyo M, Li W, Ikeda E, Mano Y, Funata S, Namba H, Fujii T, Kita K, Matsusaka K, Kaneda A.  Epstein-Barr virus-positive gastric cancer involves enhancer activation through activating transcription factor 3  Cancer Sci  2020  111(5):1818-1828  PubMed ID: 32119176   DOI: 10.1111/cas.14370
13600  Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.  p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers  Biochem Biophys Res Commun  2020  529(3):582-589.  PubMed ID: 32736677   DOI: 10.1016/j.bbrc.2020.05.168
14832  Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y.  Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines  Arch Virol  2020  165(1):207-214  PubMed ID: 31776677   DOI: 10.1007/s00705-019-04474-9
11505  Kageyama-Yahara N, Yamamichi N, Takahashi Y, Takeuchi C, Matsumoto Y, Sakaguchi Y, Koike K.  Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.  Biochem Biophys Rep  2019  18:100632  PubMed ID: 30993217   DOI: 10.1016/j.bbrep.2019.100632
11568  De Witte C, Demeyere K, De Bruyckere S, Taminiau B, Daube G, Ducatelle R, Meyer E, Haesebrouck F.  Characterization of the non-glandular gastric region microbiota in Helicobacter suis-infected versus non-infected pigs identifies a potential role for Fusobacterium gastrosuis in gastric ulceration.  Vet. Res.  2019  50(1):39  PubMed ID: 31126330   DOI: 10.1186/s13567-019-0656-9
11499  S Zhang et al  Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation  BPB Reports  2019  2,130-133   
14935  Wu D, Yan J, Shen X, Sun Y, Thulin M, Cai Y, Wik L, Shen Q, Oelrich J, Qian X, Dubois KL, Ronquist KG, Nilsson M, Landegren U, Kamali-Moghaddam M.  Profiling surface proteins on individual exosomes using a proximity barcoding assay  Nat Commun  2019  10(1):3854  PubMed ID: 31451692   DOI: 10.1038/s41467-019-11486-1
10787  Shimada S, Akiyama Y, Mogushi K, Ishigami-Yuasa M, Kagechika H, Nagasaki H, Fukamachi H, Yuasa Y, Tanaka S.  Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.  Br. J. Cancer  2018  118:972-984  PubMed ID: 29527007   DOI: 10.1038/s41416-018-0008-y
11145  Li W, Wong CC, Zhang X, Kang W, Nakatsu G, Zhao Q, Chen H, Go MYY, Chiu PWY, Wang X, Ji J, Li X, Cai Z, Ng EKW, Yu J.  CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.  Oncogene  2018  37(50):6383-6398  PubMed ID: 30054562   DOI: 10.1038/s41388-018-0402-1
11095  Kim M, Pyo S, Kang CH, Lee CO, Lee HK, Choi SU, Park CH.  Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer.  PLoS ONE  2018  13(6):e0198347  PubMed ID: 29874279   DOI: 10.1371/journal.pone.0198347
11231  Wang Z, Qu H, Gong W, Liu A.  Up-regulation and tumor-promoting role of SPHK1 were attenuated by miR-330-3p in gastric cancer.  IUBMB Life  2018    PubMed ID: 30281914   DOI: 10.1002/iub.1934
4300  Keller S, Zwingenberger G, Ebert K, Hasenauer J, Wasmuth J, Maier D, Haffner I, Schierle K, Weirich G, Luber B.  Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines.  Mol Oncol  2018    PubMed ID: 29325228   DOI: 10.1002/1878-0261.12170
4313  Kiuchi J, Komatsu S, Imamura T, Nishibeppu K, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Ichikawa D, Tsuda H, Otsuji E.  Overexpression of YEATS4 contributes to malignant outcomes in gastric carcinoma.  Am J Cancer Res  2018    PubMed ID: 30662802  
4380  Yoshioka T, Shien K, Namba K, Torigoe H, Sato H, Tomida S, Yamamoto H, Asano H, Soh J, Tsukuda K, Nagasaka T, Fujiwara T, Toyooka S.  Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer.  Cancer Sci.  2018  109(4):1166-1176  PubMed ID: 29465762   DOI: 10.1111/cas.13546
13126  Gaowa S, Futamura M, Tsuneki M, Kamino H, Tajima JY, Mori R, Arakawa H, Yoshida K.  Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.  Cancer Sci  2018    PubMed ID: 30290054   DOI: 10.1111/cas.13824
9788  Deguchi Y, Okabe H, Oshima N, Hisamori S, Minamiguchi S, Muto M, Sakai Y.  PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma.  Gastric Cancer  2017  20:416-427  PubMed ID: 27517839   DOI: 10.1007/s10120-016-0627-z
9945  Ooi A, Oyama T, Nakamura R, Tajiri R, Ikeda H, Fushida S, Dobashi Y.  Gene amplification of CCNE1, CCND1, and CDK6 in gastric cancers detected by multiplex ligation-dependent probe amplification and fluorescence in situ hybridization.  Hum. Pathol.  2017  61:58-67  PubMed ID: 27864121   DOI: 10.1016/j.humpath.2016.10.025
9978  Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, Zwingenberger G, Weichert W, Luber B.  Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines.  J. Cancer Res. Clin. Oncol.  2017  143:573-600  PubMed ID: 27933395   DOI: 10.1007/s00432-016-2308-z
10134  Qian Y, Wong CC, Xu J, Chen H, Zhang Y, Kang W, Wang H, Zhang L, Li W, Chu ESH, Go MYY, Chiu PWY, Ng EKW, Chan FKL, Sung JJY, Si J, Yu J.  Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.  Cancer Res.  2017  77:1968-1982  PubMed ID: 28202509   DOI: 10.1158/0008-5472.CAN-16-1595
10258  Gen Y, Yasui K, Kitaichi T, Iwai N, Terasaki K, Dohi O, Hashimoto H, Fukui H, Inada Y, Fukui A, Jo M, Moriguchi M, Nishikawa T, Umemura A, Yamaguchi K, Konishi H, Naito Y, Itoh Y.  ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer.  Cancer Lett.  2017  398:52-61  PubMed ID: 28400336   DOI: 10.1016/j.canlet.2017.04.002
10437  Yanoma T, Ogata K, Yokobori T, Ide M, Mochiki E, Toyomasu Y, Yanai M, Kogure N, Kimura A, Suzuki M, Nakazawa N, Bai T, Oyama T, Asao T, Shirabe K, Kuwano H.  Heat shock-induced HIKESHI protects cell viability via nuclear translocation of heat shock protein 70.  Oncol. Rep.  2017  38:1500-1506  PubMed ID: 28731175   DOI: 10.3892/or.2017.5844
10460  Li HK, Morokoshi Y, Nagatsu K, Kamada T, Hasegawa S.  Locoregional therapy with α-emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2-positive gastric cancer in mice.  Cancer Sci.  2017  108:1648-1656  PubMed ID: 28514062   DOI: 10.1111/cas.13282
10586  Ishii S, Yamashita K, Harada H, Ushiku H, Tanaka T, Nishizawa N, Yokoi K, Washio M, Ema A, Mieno H, Moriya H, Hosoda K, Waraya M, Katoh H, Watanabe M.  The H19-PEG10/IGF2BP3 axis promotes gastric cancer progression in patients with high lymph node ratios.  Oncotarget  2017  8:74567-74581  PubMed ID: 29088808   DOI: 10.18632/oncotarget.20209
5806  Shiroki T et al  Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.  Cancer Sci  2017  108(5):931-940  PubMed ID: 28235245   DOI: 10.1111/cas.13211
14227  Okabe A, Funata S, Matsusaka K, Namba H, Fukuyo M, Rahmutulla B, Oshima M, Iwama A, Fukayama M, Kaneda A.  Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus  Sci Rep  2017  7(1):7924   PubMed ID: 28801683   DOI: 10.1038/s41598-017-08370-7
14615  Nambara S, Masuda T, Nishio M, Kuramitsu S, Tobo T, Ogawa Y, Hu Q, Iguchi T, Kuroda Y, Ito S, Eguchi H, Sugimachi K, Saeki H, Oki E, Maehara Y, Suzuki A, Mimori K.  Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer  Oncotarget   2017  8(64):107666-107677  PubMed ID: 29296196   DOI: 10.18632/oncotarget.22587
14631  Funata S, Matsusaka K, Yamanaka R, Yamamoto S, Okabe A, Fukuyo M, Aburatani H, Fukayama M, Kaneda A.  Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection  Oncotarget  2017  8(33):55265-55279  PubMed ID: 28903418   DOI: 10.18632/oncotarget.19423
14663  Ito M, Migita K, Matsumoto S, Wakatsuki K, Tanaka T, Kunishige T, Nakade H, Nakatani M, Nakajima Y.  Overexpression of E3 ubiquitin ligase tripartite motif 32 correlates with a poor prognosis in patients with gastric cancer  Oncol Lett  2017  13(5):3131-3138  PubMed ID: 28521418   DOI: 10.3892/ol.2017.5806
14737  Baba K, Kitajima Y, Miyake S, Nakamura J, Wakiyama K, Sato H, Okuyama K, Kitagawa H, Tanaka T, Hiraki M, Yanagihara K, Noshiro H.  Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines  Sci Rep  2017  7(1):11127  PubMed ID: 28894280   DOI: 10.1038/s41598-017-11769-x
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5869  野田頭 達也, 小田桐 弘毅, 池永 照史郎一期, 丸山 将輝, 佐藤 利行, 袴田 健一  Cre/loxP system を用いた HER2/neu 発現細胞に対する特異的かつ効率的遺伝子導入システムの開発  弘前医学  2010  61:26―34    DOI: 10.32216/hirosakiigaku.61.1_26



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