CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB0993 : IEC 6]

1831 Quaroni A, Wands J, Trelstad, R L, Isselbacher, K J Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria. J Cell Biol 1979 80:248-65 PubMed ID: 88453 DOI: 10.1083/jcb.80.2.248

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19858 Mohamad Ishak NS, Kikuchi M, Ikemoto K. Dietary pyrroloquinoline quinone hinders aging progression in male mice and D-galactose-induced cells Front Aging 2024 5:1351860 PubMed ID: 38487591 DOI: 10.3389/fragi.2024.1351860

22002 Sadia Afrin Rimi, Md Jahangir Alam, Jaroslav Kristof, Abubakar Hamza Sadiq, Mahedi Hasan, Md. Al Mamun, Mitsutoshi Setou, Kazuo Shimizu Lipidomics of Microplasma-Irradiated Cells at Optimized Discharge Conditions for the Absorption of High-Molecule Drug Applied Sciences 2024 14:3978 DOI: 10.3390/app14103978

22153 Takizawa Y, Furuya T, Uno M, Ohashi R, Mimura E, Kurita T, Nakajima T. Specific inhibitory effects of exogenous d-Aspartate on the proliferation of intestinal epithelial cells. Biochem Biophys Res Commun 2024 734:150659 PubMed ID: 39245027 DOI: 10.1016/j.bbrc.2024.150659

17775 Yusuke Takizawa*, Koume Yoda, Miho Ishii, Yuka Nagai, Takuro Kurita, Takanori Nakajima The influence of 2-acetyl-4(5)-tetrahydroxybutylimidazole (THI) in caramel coloring III on gastrointestinal epithelial cells J. Excipients and Food Chem 2023 14:22-32

19613 Sadia Afrin Rimi, Jaroslav Kristof, Md Jahangir Alam, Kyohei Oishi, Takumi Okada, Abubakar Hamza Sadiq, Kazuo Shimizu Changes in Membrane Lipid Order of Cells by Optimized Microplasma Irradiation for High-Molecule Drug Absorption Plasma Medicine 2023 13:15-32 DOI: 10.1615/plasmamed.2023050304

20460 Akao Y, Kuranaga Y, Heishima K, Sugito N, Morikawa K, Ito Y, Soga T, Ito T. Plant hvu-MIR168-3p enhances expression of glucose transporter 1 (SLC2A1) in human cells by silencing genes related to mitochondrial electron transport chain complex I. J Nutr Biochem 2022 108922 PubMed ID: 34856354 DOI: 10.1016/j.jnutbio.2021.108922

16737 Yusuke Takizawa, Junya Oguri, Masaya Uno, Ami Onsui, Atsushi Ishimura, Takuro Kurita, Takanori Nakajima Effects of A GLP‑1 Receptor Agonist on Gastrointestinal Epithelial Cells Scholars Academic Journal of Pharmacy 2022 11:60-66 DOI: 10.36347/sajp.2022.v11i04.002

20951 Huang IH, Miyashita SI, Hata T, Karatsu S, Hosoya K, Sagane Y. Complete subunit structure of serotype C and D botulinum progenitor toxin complex induces vacuolation in the specific epithelial cell line. Biochem Biophys Res Commun 2022 632:55-61 PubMed ID: 36201881 DOI: 10.1016/j.bbrc.2022.09.093

21150 Hosoya K, Miyashita SI, Karatsu S, Huang IH, Sagane Y. Species-specific gene duplication in Clostridia produces variations of cholesterol-dependent cytolysin with different cytotoxicity. Biochem Biophys Res Commun 2022 637:240-246 PubMed ID: 36410272 DOI: 10.1016/j.bbrc.2022.11.043

17777 Yusuke Takizawa*, Mizuki Arakawa, Takuro Kurita, Takanori Nakajima The influence of 4-methylimidazole on the gastrointestinal epithelial cells J. Excipients and Food Chem 2021 12:4-15

20151 Guo M, Xu W, Yamamoto Y, Suzuki T. Curcumin increases heat shock protein 70 expression via different signaling pathways in intestinal epithelial cells. Arch Biochem Biophys 2021 707:108938 PubMed ID: 34051214 DOI: 10.1016/j.abb.2021.108938

20343 Xu W, Watanabe K, Mizukami Y, Yamamoto Y, Suzuki T. Hydrogen sulfide suppresses the proliferation of intestinal epithelial cells through cell cycle arrest. Arch Biochem Biophys 2021 109044 PubMed ID: 34597656 DOI: 10.1016/j.abb.2021.109044

16834 Ito Y, Taniguchi K, Kuranaga Y, Eid N, Inomata Y, Lee SW, Uchiyama K. Uptake of MicroRNAs from Exosome-Like Nanovesicles of Edible Plant Juice by Rat Enterocytes Int J Mol Sci 2021 22(7):3749 PubMed ID: 33916868 DOI: 10.3390/ijms22073749

11431 Matsui T, Ichikawa H, Fujita T, Takemura S, Takagi T, Osada-Oka M, Minamiyama Y. Histidine and arginine modulate intestinal cell restitution via transforming growth factor-β1. Eur. J. Pharmacol. 2019 PubMed ID: 30753862 DOI: 10.1016/j.ejphar.2019.02.006

9160 Minori Kubota, Kazuki Kakimoto, Takatoshi Nakagawa, Eiko Koubayashi, Kei Nakazawa, Hideki Tawa, Yuki Hirata, Toshihiko Okada, Ken Kawakami, Akira Asai, Shuhei Hosomi, Toshihisa Takeuchi, Shinya Fukunishi, Takuya Inoue, Michio Asahi, Kazuhide Higuchi Autophagy Deficiency Exacerbates Colitis Through Excessive Oxidative Stress and MAPK Signaling Pathway Activation PLoS One 2019 14 (11), e0225066 PubMed ID: 31703091 DOI: 10.1371/journal.pone.0225066

12474 Makino Y, Munakata S, Ueyama T, Honjo K, Kawano S, Takahashi M, Kojima Y, Tomiki Y, Sakamoto K. Effects of Receptor for Advanced Glycation End-Products (RAGE) Signaling on Intestinal Ischemic Damage in Mice Eur Surg Res 2019 60(5-6):239-247 PubMed ID: 31914449 DOI: 10.1159/000504751

10726 Mashima H, Watanabe N, Sekine M, Matsumoto S, Asano T, Yuhashi K, Sagihara N, Urayoshi S, Uehara T, Fujiwara J, Ishii T, Tsuboi R, Miyatani H, Ohnishi H. The role of Gαq/Gα11 signaling in intestinal epithelial cells. Biochem Biophys Rep 2018 13:93-98 PubMed ID: 29387814 DOI: 10.1016/j.bbrep.2018.01.003

10825 Islam MS, Kaji N, Mikawa S, Yang Q, Kusabe M, Hori M, Ozaki H. Induction of myosin light chain kinase and CPI-17 by TGF-β accelerates contractile activity in intestinal epithelial cells. J. Vet. Med. Sci. 2018 80(6):977-984 PubMed ID: 29695674 DOI: 10.1292/jvms.17-0684

12475 Kawano M, Miura T, Fujita M, Koike S, Imadome K, Ishikawa A, Yasuda T, Imamura T, Imai T, Nakayama F. The FGF1/CPP-C chimera protein protects against intestinal adverse effects of C-ion radiotherapy without exacerbating pancreatic carcinoma Clin Transl Radiat Oncol 2018 14:8-16 PubMed ID: 30406211 DOI: 10.1016/j.ctro.2018.10.004

9907 Kojo Y, Matsunaga S, Suzuki H, Sato H, Seto Y, Onoue S. Improved oral absorption profile of itraconazole in hypochlorhydria by self-micellizing solid dispersion approach. Eur J Pharm Sci 2017 97:55-61 PubMed ID: 27810562 DOI: 10.1016/j.ejps.2016.10.032

10382 Tsukahara T, Hamouda N, Utsumi D, Matsumoto K, Amagase K, Kato S. G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells. Pharmacol. Res. 2017 123:27-39 PubMed ID: 28648739 DOI: 10.1016/j.phrs.2017.06.009

10414 Kamao M, Hirota Y, Suhara Y, Tsugawa N, Nakagawa K, Okano T, Hasegawa H. Determination of Menadione by Liquid Chromatography-Tandem Mass Spectrometry Using Pseudo Multiple Reaction Monitoring. Anal Sci 2017 33:863-867 PubMed ID: 28690267 DOI: 10.2116/analsci.33.863

3919 Tatsunobu Matsui, Hiroshi Ichikawa, Tomoka Fujita, Tomohisa Takagi, Mayuko Osada-Oka, Yukiko Minamiyama Histidine deficiency attenuates cell viability in rat intestinal epithelial cells by apoptosis via mitochondrial dysfunction Journal of Nutrition & Intermediary Metabolism 2017 8:21-28 DOI: 10.1016/j.jnim.2017.05.002

9781 Miyashita S, Sagane Y, Suzuki T, Matsumoto T, Niwa K, Watanabe T. Non-Toxic Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity. Sci Rep 2016 6:31043 PubMed ID: 27507612 DOI: 10.1038/srep31043

10931 Interleukin-33, an interleukin-1 like cytokine accelerates cell migration in IEC-6 cells Asian Journal of Medical and Biological Research 2016 2 DOI: 10.3329/ajmbr.v2i4.30999

12692 Narita T, Naganuma T, Sase Y, Kihara A. Long-chain bases of sphingolipids are transported into cells via the acyl-CoA synthetases Sci Rep 2016 6:25469 PubMed ID: 27136724 DOI: 10.1038/srep25469

13969 Islam MS, Horiguchi K, Iino S, Kaji N, Mikawa S, Hori M, Ozaki H. Epidermal growth factor is a critical regulator of the cytokine IL-33 in intestinal epithelial cells Br J Pharmacol 2016 173(16):2532-42 PubMed ID: 27300306 DOI: 10.1111/bph.13535

7156 Yokoe S, Nakagawa T, Kojima Y, Higuchi K, Asahi M. Indomethacin-induced intestinal epithelial cell damage is mediated by pVHL activation through the degradation of collagen I and HIF-1α. Biochem. Biophys. Res. Commun. 2015 468:671-6 PubMed ID: 26551465 DOI: 10.1016/j.bbrc.2015.11.014

9147 Satoshi Harada, Takatoshi Nakagawa, Shunichi Yokoe, Shoko Edogawa, Toshihisa Takeuchi, Takuya Inoue, Kazuhide Higuchi, Michio Asahi Autophagy Deficiency Diminishes Indomethacin-Induced Intestinal Epithelial Cell Damage Through Activation of the ERK/Nrf2/HO-1 Pathway J Pharmacol Exp Ther 2015 355 (3), 353-61 PubMed ID: 26404472 DOI: 10.1124/jpet.115.226431

9191 Ken Narabayashi, Yuko Ito, Nabil Eid, Kentaro Maemura, Takuya Inoue, Toshihisa Takeuchi, Yoshinori Otsuki, Kazuhide Higuchi Indomethacin Suppresses LAMP-2 Expression and Induces Lipophagy and Lipoapoptosis in Rat Enterocytes via the ER Stress Pathway J Gastroenterol 2015 50 (5), 541-54 PubMed ID: 25212253 DOI: 10.1007/s00535-014-0995-2

15199 Miyata K, Suzuki T, Hayashi S, Miyashita S, Ohyama T, Niwa K, Watanabe T, Sagane Y. Hemagglutinin gene shuffling among Clostridium botulinum serotypes C and D yields distinct sugar recognition of the botulinum toxin complex Pathog Dis 2015 73(7):ftv05 PubMed ID: 26223883 DOI: 10.1093/femspd/ftv054

16235 Saito R, Tamura M, Matsui H, Nagano Y, Suzuki H, Kaneko T, Mizokami Y, Hyodo I. Qing Dai attenuates nonsteroidal anti-inflammatory drug-induced mitochondrial reactive oxygen species in gastrointestinal epithelial cells J Clin Biochem Nutr 2015 56(1):8-14 PubMed ID: 25678747 DOI: 10.3164/jcbn.14-59

10262 Shin-Ichiro Miyashita, Koichi Niwa, Toshihiro Watanabe, Yoshimasa Sagane Host-cell Specificity and Transcytosis of Nontoxic Nonhemagglutinin Protein of Botulinum Neurotoxin Serotype D FEMS Microbiol Lett 2014 2014 Aug;357(2):115-22 PubMed ID: 25041523 DOI: 10.1111/1574-6968.12527

15923 Yamawaki H, Mihara H, Suzuki N, Nishizono H, Uchida K, Watanabe S, Tominaga M, Sugiyama T. Role of transient receptor potential vanilloid 4 activation in indomethacin-induced intestinal damage Am J Physiol Gastrointest Liver Physiol 2014 307(1):G33-40 PubMed ID: 24789205 DOI: 10.1152/ajpgi.00105.2013

19008 Yamada Y, Mashima H, Sakai T, Matsuhashi T, Jin M, Ohnishi H. Functional roles of TGF-β1 in intestinal epithelial cells through Smad-dependent and non-Smad pathways Dig Dis Sci 2013 58(5):1207-17 PubMed ID: 23306843 DOI: 10.1007/s10620-012-2515-7

12707 Sekiya M, Kiyohara H, Maruyama H, Yabe T, Yamada H. Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito, and its active ingredients J Nat Med 2013 67(3):626-35 PubMed ID: 23203627 DOI: 10.1007/s11418-012-0724-1

12728 Miyashita S, Sagane Y, Inui K, Hayashi S, Miyata K, Suzuki T, Ohyama T, Watanabe T, Niwa K. Botulinum toxin complex increases paracellular permeability in intestinal epithelial cells via activation of p38 mitogen-activated protein kinase J Vet Med Sci 2013 75(12):1637-42 PubMed ID: 23884081 DOI: 10.1292/jvms.13-0164

12709 Miyashita S, Sagane Y, Niwa K, Watanabe T. Transport of the botulinum neurotoxin-associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer FEMS Microbiol Lett 2013 346(1):73-80 PubMed ID: 23809018 DOI: 10.1111/1574-6968.12205

16297 Hirota Y, Tsugawa N, Nakagawa K, Suhara Y, Tanaka K, Uchino Y, Takeuchi A, Sawada N, Kamao M, Wada A, Okitsu T, Okano T. Menadione (vitamin K3) is a catabolic product of oral phylloquinone (vitamin K1) in the intestine and a circulating precursor of tissue menaquinone-4 (vitamin K2) in rats J Biol Chem 2013 288(46):33071-80 PubMed ID: 24085302 DOI: 10.1074/jbc.M113.477356

7726 Tamaki K, Otaka M, Shibuya T, Sakamoto N, Yamamoto S, Odashima M, Itoh H, Watanabe S. Traditional Herbal Medicine, Rikkunshito, Induces HSP60 and Enhances Cytoprotection of Small Intestinal Mucosal Cells as a Nontoxic Chaperone Inducer. Evid Based Complement Alternat Med 2012 2012:278958 PubMed ID: 21822440 DOI: 10.1155/2012/278958

3894 Nagano Y1, Matsui H, Shimokawa O, Hirayama A, Tamura M, Nakamura Y, Kaneko T, Rai K, Indo HP, Majima HJ, Hyodo I. Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells. J Physiol Pharmacol 2012 63(2):137-42 PubMed ID: 22653900

3909 Nagano Y, Matsui H, Shimokawa O, Hirayama A, Nakamura Y, Tamura M, Rai K, Kaneko T, Hyodo I. Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation. J Clin Biochem Nutr 2012 51(3):196-203 PubMed ID: 23170047 DOI: 10.3164/jcbn.12-41

17936 Nakayama F, Yasuda T, Umeda S, Asada M, Imamura T, Meineke V, Akashi M. Fibroblast growth factor-12 (FGF12) translocation into intestinal epithelial cells is dependent on a novel cell-penetrating peptide domain: involvement of internalization in the in vivo role of exogenous FGF12 J Biol Chem 2011 286(29):25823-34 PubMed ID: 21518765 DOI: 10.1074/jbc.M110.198267

7796 Matsuo T, Miyata K, Inui K, Ito H, Horiuchi R, Suzuki T, Yoneyama T, Oguma K, Niwa K, Watanabe T, Ohyama T. Characterization of sugar recognition by the toxin complex produced by the Clostridium botulinum serotype C variant strain Yoichi. FEMS Immunol. Med. Microbiol. 2011 63:35-43 PubMed ID: 21635567 DOI: 10.1111/j.1574-695X.2011.00825.x

7890 Ishihara H, Tanaka I, Yakumaru H, Tanaka M, Satoh A, Ishiwata A, Yokochi K, Kurematsu A, Ueda J, Shibata T, Hachiya M, Akashi M. Acceleration of regeneration of mucosa in small intestine damaged by ionizing radiation using anabolic steroids. Radiat. Res. 2011 175:367-74 PubMed ID: 21388280 DOI: 10.1667/RR2154.1

7981 Tamaki K, Otaka M, Takada M, Yamamoto S, Odashima M, Itoh H, Watanabe S. Evidence for enhanced cytoprotective function of HSP90-overexpressing small intestinal epithelial cells. Dig. Dis. Sci. 2011 56:1954-61 PubMed ID: 21253835 DOI: 10.1007/s10620-010-1558-x

7998 Ito H, Sagane Y, Miyata K, Inui K, Matsuo T, Horiuchi R, Ikeda T, Suzuki T, Hasegawa K, Kouguchi H, Oguma K, Niwa K, Ohyama T, Watanabe T. HA-33 facilitates transport of the serotype D botulinum toxin across a rat intestinal epithelial cell monolayer. FEMS Immunol. Med. Microbiol. 2011 61:323-31 PubMed ID: 21219447 DOI: 10.1111/j.1574-695X.2011.00779.x

8245 Takeda K, Hashimoto K, Uchikawa R, Tegoshi T, Yamada M, Arizono N. Direct effects of IL-4/IL-13 and the nematode Nippostrongylus brasiliensis on intestinal epithelial cells in vitro. Parasite Immunol. 2010 32:420-9 PubMed ID: 20500673 DOI: 10.1111/j.1365-3024.2010.01200.x

8339 Sato N, Morimoto H, Baba R, Nakamata J, Doi Y, Yamaguchi K. Functional expression of double-stranded RNA-dependent protein kinase in rat intestinal epithelial cells. J. Cell. Biochem. 2010 110:104-11 PubMed ID: 20213745 DOI: 10.1002/jcb.22513

8361 Takada M, Otaka M, Takahashi T, Izumi Y, Tamaki K, Shibuya T, Sakamoto N, Osada T, Yamamoto S, Ishida R, Odashima M, Itoh H, Watanabe S. Overexpression of a 60-kDa heat shock protein enhances cytoprotective function of small intestinal epithelial cells. Life Sci. 2010 86:499-504 PubMed ID: 20159025 DOI: 10.1016/j.lfs.2010.02.010

8485 Niwa K, Yoneyama T, Ito H, Taira M, Chikai T, Kouguchi H, Suzuki T, Hasegawa K, Miyata K, Inui K, Ikeda T, Watanabe T, Ohyama T. Sialic acid-dependent binding and transcytosis of serotype D botulinum neurotoxin and toxin complex in rat intestinal epithelial cells. Vet. Microbiol. 2010 141:312-20 PubMed ID: 19786330 DOI: 10.1016/j.vetmic.2009.09.008

12756 Inui K, Ito H, Miyata K, Matsuo T, Horiuchi R, Ikeda T, Watanabe T, Ohyama T, Niwa K. Involvement of sialic acid in transport of serotype C1 botulinum toxins through rat intestinal epithelial cells J Vet Med Sci 2010 72(9):1251-5 PubMed ID: 20453451 DOI: 10.1292/jvms.10-0090

12806 Shoji H, Oguchi S, Shinohara K, Shimizu T, Yamashiro Y. Effects of iron-unsaturated human lactoferrin on hydrogen peroxide-induced oxidative damage in intestinal epithelial cells Pediatr Res 2007 61(1):89-92. PubMed ID: 17211147 DOI: 10.1203/01.pdr.0000250198.22735.20

3877 Yuki T, Ishihara S, Rumi MA, Ortega-Cava CF, Kadowaki Y, Kazumori H, Ishimura N, Amano Y, Moriyama N, Kinoshita Y. Increased expression of midkine in the rat colon during healing of experimental colitis. Am J Physiol Gastrointest Liver Physiol 2006 291(4):G735-43 PubMed ID: 16959957 DOI: 10.1152/ajpgi.00388.2005

3408 Qian, Wei, Nishikawa, Manabu, Haque, Anwarul Md, Hirose, Masaki, Mashimo, Masayuki, Sato, Eisuke, Inoue, Masayasu Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death. Am J Physiol Cell Physiol 2005 289:C1466-75 PubMed ID: 16107504 DOI: 10.1152/ajpcell.00265.2005

2907 Uesaka T, Kageyama N, Watanabe H Identifying target genes regulated downstream of Cdx2 by microarray analysis. J Mol Biol 2004 337:647-60 PubMed ID: 15019784 DOI: 10.1016/j.jmb.2004.01.061

2864 Ikenoue, Tsuneo, Hikiba, Yohko, Kanai, Fumihiko, Aragaki, Jun, Tanaka, Yasuo, Imamura, Jun, Imamura, Takaaki, Ohta, Miki, Ijichi, Hideaki, Tateishi, Keisuke, Kawakami, Takayuki, Matsumura, Masayuki, Kawabe, Takao, Omata, Masao Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation. Cancer Res 2004 64:3428-35 PubMed ID: 15150094 DOI: 10.1158/0008-5472.CAN-03-3591

3178 Uesaka, Toshihiro, Kageyama, Noriko Cdx2 homeodomain protein regulates the expression of MOK, a member of the mitogen-activated protein kinase superfamily, in the intestinal epithelial cells. FEBS Lett 2004 573:147-54 PubMed ID: 15327990 DOI: 10.1016/j.febslet.2004.07.070

18572 Kuroda A, Uchikawa R, Matsuda S, Yamada M, Tegoshi T, Arizono N. Up-regulation of Fas (CD95) and induction of apoptosis in intestinal epithelial cells by nematode-derived molecules Infect Immun 2002 70(8):4002-8 PubMed ID: 12117905 DOI: 10.1128/IAI.70.8.4002-4008.2002

18647 Yoshida S, Kajimoto Y, Yasuda T, Watada H, Fujitani Y, Kosaka H, Gotow T, Miyatsuka T, Umayahara Y, Yamasaki Y, Hori M. PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells Diabetes 2002 51(8):2505-13 PubMed ID: 12145164 DOI: 10.2337/diabetes.51.8.2505

3789 Uesaka T, Lu H, Katoh O, Watanabe H. Heparin-binding EGF-like growth factor gene transcription regulated by Cdx2 in the intestinal epithelium. Am J Physiol Gastrointest Liver Physiol 2002 283(4):G840-7 PubMed ID: 12223343 DOI: 10.1152/ajpgi.00075.2002

2306 Hiyoshi M, Ohkubo T, Tsuji K, Hagihara M, Nakasaki H, Mukai M, Makuuchi H, Yamamura M, Tsuda M. Hepatocyte proliferation factors from neonatal pig liver: purification and characterization Biofactors 2002 16(1-2):1-14 PubMed ID: 12515911 DOI: 10.1002/biof.5520160101

3832 Mizuno M, Okayama N, Kasugai K, Yoshida T, Miyata M, Nitta M, Kataoka H, Akita S, Joh T, Itoh M, Asai K, Kato T. Acid stimulates E-cadherin surface expression on gastric epithelial cells to stabilize barrier functions via influx of calcium. Eur J Gastroenterol Hepatol. 2001 13(2):127-36 PubMed ID: 11246611 DOI: 10.1097/00042737-200102000-00007

3809 Hassan S, Kinoshita Y, Okada A, Maekawa T, Fukui H, Chiba T. Geranylgeranylacetone, an anti-ulcer drug, stimulates hexosamine production in a rat gastric mucosal cell line through binding to a specific cytosolic protein. J Gastroenterol Hepatol. 1998 13(8):809-15 PubMed ID: 9736174 DOI: 10.1111/j.1440-1746.1998.tb00737.x

1397 Nishikawa M, Takeda K, Sato EF, Kuroki T, Inoue M. Nitric oxide regulates energy metabolism and Bcl-2 expression in intestinal epithelial cells Am J Physiol 1998 274(5):G797-801 PubMed ID: 9612258 DOI: 10.1152/ajpgi.1998.274.5.G797