Search
CELL BANK Website

Back Back
RCB0876 : RGM1  update : 2018/07/06
CommentSo called clear cells from rat stomach mucosa.
Comment from the depositor
Terms and conditionsA prior written permission of the approver(Depositor) is necessary for any kind of use including academic use and for-profit use.
Remarks
approver's address
×
English
Address
Graduate School of Comprehensive Human Sciences, University of Tsukuba

1-1-1, Tenno-dai, Tsukuba, Ibaraki, 305-8577, Japan
Dr.Matsui, Hirofumi
Fax. +81-29-853-3321
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Matsui, Hirofumi
Originator Matsui, H. & Ohno, T.
Year of deposit 1993
Animal rat < Mammals
Strain name Wistar
Genus Rattus
Species norvegicus
Gender Male
Age at sampling 3 months
Tissue gastric mucosa
Classification other
Year of origin 1989
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM/HamF12 + 20% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 1-2 times/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
Isozyme LD, NP, MPI, PepB
Reference information Reference 15
User's Publication 125


To topTop
Reference
3511  Kusuhara H, Matsuyuki H, Matsuura M, Imayoshi T, Okumoto T, Matsui H.  Induction of apoptotic DNA fragmentation by nonsteroidal anti-inflammatory drugs in cultured rat gastric mucosal cells.  Eur J Pharmacol  1998  360(2-3):273-80  PubMed ID: 9851595
3840  Matsui H, Murata Y, Kobayashi F, Shiba R, Momo K, Kondo Y, Nakahara A, Muto H.  Diclofenac-induced gastric mucosal fluorescence in rats.  Dig Dis Sci  2001  46(2):338-44  PubMed ID: 1281183
3879  Kaneko T, Matsui H, Shimokawa O, Nakahara A, Hyodo I.  Cellular membrane fluidity measurement by fluorescence polarization in indomethacin-induced gastric cellular injury in vitro.  J Gastroenterol  2007  42(12):939-46  PubMed ID: 18085350
3880  Ushida Y, Shimokawa Y, Toida T, Matsui H, Takase M.  Bovine alpha-lactalbumin stimulates mucus metabolism in gastric mucosa.  J Dairy Sci  2007  90(2):541-6  PubMed ID: 17235130
3883  Sekiguchi F, Saito S, Takaoka K, Hayashi H, Nagataki M, Nagasawa K, Nishikawa H, Matsui H, Kawabata A.  Mechanisms for prostaglandin E2 formation caused by proteinase-activated receptor-1 activation in rat gastric mucosal epithelial cells.  Biochem Pharmacol  2007  73(1):103-14  PubMed ID: 17069767
3888  Shimokawa O, Matsui H, Nagano Y, Kaneko T, Shibahara T, Nakahara A, Hyodo I, Yanaka A, Majima HJ, Nakamura Y, Matsuzaki Y.  Neoplastic transformation and induction of H+,K+ -adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line.  In Vitro Cell Dev Biol Anim  2008  44(1-2):26-30  PubMed ID: 18034283
3898  SB Olaleye, CH Cho  Antiulcerogenic Effects of Kolaviron: Inhibition of Apoptosis induced by Indomethacin in the intact Rat Stomach and Rat Gastric Mucosa Cell line  African Journal of Biomedical Research  2010  13 
3903  Matsui H, Nagano Y, Shimokawa O, Kaneko T, Rai K, Udo J, Hirayama A, Nakamura Y, Indo HP, Majima HJ, Hyodo I.  Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells.  J Gastroenterol  2011  46(10):1167-76  PubMed ID: 21789481
3904  Hitomi Okada, Yuji Naito, Tomohisa Takagi, Megumi Takaoka, Tomoko Oya-Ito, Kohei Fukumoto, Kazuhiko Uchiyama, Osamu Handa, Satoshi Kokura, Yumiko Nagano, Hirofumi Matsui, Yoji Kato, Toshihiko Osawa, Toshikazu Yoshikawa  Detection of Nε-(hexanoyl)lysine in the tropomyosin 1 protein in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric cancer cells  Journal of Clinical Biochemistry and Nutrition  2011  50 :47 
3905  Nagano Y, Matsui H, Tamura M, Shimokawa O, Nakamura Y, Kaneko T, Hyodo I.  NSAIDs and acidic environment induce gastric mucosal cellular mitochondrial dysfunction.  Digestion  2012  85(2):131-5  PubMed ID: 22269294
3906  Nagano Y, Matsui H, Shimokawa O, Hirayama A, Tamura M, Nakamura Y, Kaneko T, Rai K, Indo HP, Majima HJ, Hyodo I.  Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells.  J Physiol Pharmacol  2012  63(2):137-42  PubMed ID: 22653900
3908  Nagano Y, Matsui H, Shimokawa O, Hirayama A, Nakamura Y, Tamura M, Rai K, Kaneko T, Hyodo I.  Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation.  J Clin Biochem Nutr  2012  51(3):196-203  PubMed ID: 23170047
3912  Nakamizo H, Suzuki H, Miura S, Mogami S, Kishikawa H, Yoshida H, Matsui H, Hibi T.  Transmural pressure loading enhances gastric mucosal cell proliferation.  Dig Dis Sci  2012  57(10):2545-54  PubMed ID: 22644739
3913  Kazuhiro Hiyama, Hirofumi Matsui, Masato Tamura, Osamu Shimokawa, Mariko Hiyama, Tsuyoshi Kaneko, Yumiko Nagano, Ichinosuke Hyodo, Junko Tanaka, Yoshihiro Miwa, Tetsuo Ogawa, Takeo Nakanishi and Ikumi Tamai  Cancer cells uptake porphyrins via heme carrier protein 1  Journal of Porphyrins and Phthalocyanines  2013  17:36-43 
3915  Okabe S, Okamoto T, Zhao CM, Chen D, Matsui H.  Acetic acid induces cell death: an in vitro study using normal rat gastric mucosal cell line and rat and human gastric cancer and mesothelioma cell lines.  J Gastroenterol Hepatol  2014  29 Suppl 4:65-9  PubMed ID: 25521736

To topTop
User's Publication
3429  Stoicov, Calin, Cai, Xun, Li, Hanchen, Klucevsek, Kristine, Carlson, Jane, Saffari, Reza, Houghton, Jeanmarie  Major histocompatibility complex class II inhibits fas antigen-mediated gastric mucosal cell apoptosis through actin-dependent inhibition of receptor aggregation.  Infect Immun  2005  73:6311-21  PubMed ID: 16177302
2049  Hassan S, Kinoshita Y, Min D, Nakata H, Kishi K, Matsushima Y, Asahara M, Wang, H Y, Okada A, Maekawa T, Matsui H, Chiba T  Presence of prostaglandin EP4 receptor gene expression in a rat gastric mucosal cell line.  Digestion  1996  57:196-200  PubMed ID: 8739095
3062  Odashima, Masaru, Otaka, Michiro, Jin, Mario, Konishi, Noriaki, Sato, Toshihiro, Kato, Sayuri, Matsuhashi, Tamotsu, Nakamura, Chieko, Watanabe, Sumio  Induction of a 72-kDa heat-shock protein in cultured rat gastric mucosal cells and rat gastric mucosa by zinc L-carnosine.  Dig Dis Sci  2002  47:2799-804  PubMed ID: 12498304
3367  Luo, Jiing Chyuan, Shin, Vivian Yvonne, Yang, Ying Hua, Wu, William Ka Kei, Ye, Yi Ni, So, Wallace Hau Leung, Chang, Full Young, Cho, Chi Hin  Tumor necrosis factor-alpha stimulates gastric epithelial cell proliferation.  Am J Physiol Gastrointest Liver Physiol  2005  288:G32-8  PubMed ID: 15256360
2847  Mustonen, Harri, Kiviluoto, Tuula, Paimela, Hannu, Puolakkainen, Pauli, Kivilaakso, Eero  Calcium signaling is involved in ethanol-induced volume decrease and gap junction closure in cultured rat gastric mucosal cells.  Dig Dis Sci  2005  50:103-10  PubMed ID: 15712646
3192  Mustonen, Harri, Lepisto, Anna, Lehtonen, Sanna, Lehtonen, Eero, Puolakkainen, Pauli, Kivilaakso, Eero  CD2AP contributes to cell migration and adhesion in cultured gastric epithelium.  Biochem Biophys Res Commun  2005  332:426-32  PubMed ID: 15910750
7344  Kumar JD, Steele I, Moore AR, Murugesan SV, Rakonczay Z, Venglovecz V, Pritchard DM, Dimaline R, Tiszlavicz L, Varro A, Dockray GJ.  Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration.  Am. J. Physiol. Gastrointest. Liver Physiol.  2015  309:G78-86  PubMed ID: 25977510
7654  Habe H, Sato S, Fukuoka T, Kitamoto D, Sakaki K.  Effect of glyceric acid calcium salt on the viability of ethanol-dosed gastric cells.  J Oleo Sci  2011  60:585-90  PubMed ID: 22027025
7751  Rai K, Matsui H, Kaneko T, Nagano Y, Shimokawa O, Udo J, Hirayama A, Hyodo I, Indo HP, Majima HJ.  Lansoprazole inhibits mitochondrial superoxide production and cellular lipid peroxidation induced by indomethacin in RGM1 cells.  J Clin Biochem Nutr  2011  49:25-30  PubMed ID: 21765603
7899  Naito Y, Takagi T, Katada K, Tomatsuri N, Mizushima K, Handa O, Kokura S, Yagi N, Ichikawa H, Yoshikawa T.  Gastric peroxisome proliferator activator receptor-γ expression and cytoprotective actions of its ligands against ischemia-reperfusion injury in rats.  J Clin Biochem Nutr  2011  48:170-7  PubMed ID: 21373272
7944  Sekiguchi F, Ohi A, Maeda Y, Takaoka K, Sekimoto T, Nishikawa H, Kawabata A.  Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells.  J. Cell. Biochem.  2011  112:909-15  PubMed ID: 21328464
8019  Endo S, Matsunaga T, Ohta C, Soda M, Kanamori A, Kitade Y, Ohno S, Tajima K, El-Kabbani O, Hara A.  Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.  Chem. Biol. Interact.  2010  191:261-8  PubMed ID: 21187079
8204  Jones MK, Padilla OR, Zhu E.  Survivin is a key factor in the differential susceptibility of gastric endothelial and epithelial cells to alcohol-induced injury.  J. Physiol. Pharmacol.  2010  61:253-64  PubMed ID: 20610854
8267  Chai J, Norng M, Modak C, Reavis KM, Mouazzen W, Pham J.  CCN1 induces a reversible epithelial-mesenchymal transition in gastric epithelial cells.  Lab. Invest.  2010  90:1140-51  PubMed ID: 20458273
8381  Xu Y, Watanabe T, Tanigawa T, Machida H, Okazaki H, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Oshitani N, Arakawa T.  Bile acids induce cdx2 expression through the farnesoid x receptor in gastric epithelial cells.  J Clin Biochem Nutr  2010  46:81-6  PubMed ID: 20104269
8384  Amagase K, Nakamura E, Endo T, Hayashi S, Hasumura M, Uneyama H, Torii K, Takeuchi K.  New frontiers in gut nutrient sensor research: prophylactic effect of glutamine against Helicobacter pylori-induced gastric diseases in Mongolian gerbils.  J. Pharmacol. Sci.  2010  112:25-32  PubMed ID: 20093785
8435  Takaoka K, Sekiguchi F, Shigi H, Maeda Y, Nishikawa H, Kawabata A.  Opposite effects of two thiazolidinediones, ciglitazone and troglitazone, on proteinase-activated receptor-1-triggered prostaglandin E(2) release.  Toxicology  2010  268:40-5  PubMed ID: 19954759
8484  Luo JC, Cho CH, Ng KM, Hsiang KW, Lu CL, Chen TS, Chang FY, Lin HC, Perng CL, Lee SD.  Dexamethasone inhibits tumor necrosis factor-alpha-stimulated gastric epithelial cell migration.  J Chin Med Assoc  2009  72:509-14  PubMed ID: 19837644
8528  Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T.  Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.  J. Pharmacol. Exp. Ther.  2009  331:255-64  PubMed ID: 19628634
8712  Mustonen H, Puolakkainen P, Kemppainen E, Kiviluoto T, Kivilaakso E.  Taurocholate potentiates ethanol-induced NF-kappaB activation and inhibits caspase-3 activity in cultured rat gastric mucosal cells.  Dig. Dis. Sci.  2009  54:928-36  PubMed ID: 18989778
8735  Luo JC, Lin HY, Lu CL, Wang LY, Chang FY, Lin HC, Huang YC, Ng KM, Chi CW, Lee SD.  Dexamethasone inhibits basic fibroblast growth factor-stimulated gastric epithelial cell proliferation.  Biochem. Pharmacol.  2008  76:841-9  PubMed ID: 18692028
8853  Luo JC, Chi CW, Lin HY, Chang FY, Lu CL, Chen CY, Lee SD.  Dexamethasone inhibits epidermal growth factor-stimulated gastric epithelial cell proliferation.  J. Pharmacol. Exp. Ther.  2006  320:687-94  PubMed ID: 17077316
8878  Yang YH, Wu WK, Tai EK, Wong HP, Lam EK, So WH, Shin VY, Cho CH.  The cationic host defense peptide rCRAMP promotes gastric ulcer healing in rats.  J. Pharmacol. Exp. Ther.  2006  318:547-54  PubMed ID: 16670350
8886  Ni Z, Okeley NM, Smart BP, Gelb MH.  Intracellular actions of group IIA secreted phospholipase A2 and group IVA cytosolic phospholipase A2 contribute to arachidonic acid release and prostaglandin production in rat gastric mucosal cells and transfected human embryonic kidney cells.  J. Biol. Chem.  2006  281:16245-55  PubMed ID: 16603549
10331  Tu PS, Tung YT, Lee WT, Yen GC.  Protective Effect of Camellia Oil (Camellia oleifera Abel.) against Ethanol-Induced Acute Oxidative Injury of the Gastric Mucosa in Mice.  J. Agric. Food Chem.  2017  65:4932-4941  PubMed ID: 28562049
11447  Ahluwalia A, Jones MK, Hoa N, Tarnawski AS.  Mitochondria in gastric epithelial cells are the key targets for NSAIDs-induced injury and NGF cytoprotection.  J. Cell. Biochem.  2019    PubMed ID: 30790334
3757  Osada T, Watanabe S, Tanaka H, Hirose M, Miyazaki A, Sato N.  Effect of mechanical strain on gastric cellular migration and proliferation during mucosal healing: role of Rho dependent and Rac dependent cytoskeletal reorganisation.  Gut  1999  45(4):508-15  PubMed ID: 10486357
3763  Takaishi S, Sawada M, Morita Y, Seno H, Fukuzawa H, Chiba T.  Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells.  Biochem Biophys Res Commun  2000  19;267(2):658-62  PubMed ID: 10631118
3776  Pai R, Szabo IL, Giap AQ, Kawanaka H, Tarnawski AS.  Nonsteroidal anti-inflammatory drugs inhibit re-epithelialization of wounded gastric monolayers by interfering with actin, Src, FAK, and tensin signaling.  Life Sci  2001  69(25-26):3055-71  PubMed ID: 11758831
3782  Pai R, Soreghan B, Szabo IL, Pavelka M, Baatar D, Tarnawski AS.  Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy.  Nat Med  2002  8(3):289-93  PubMed ID: 11875501
3798  Netzer P, Halter F, Ma TY, Hoa N, Nguyen N, Nakamura T, Tarnawski AS.  Interaction of hepatocyte growth factor and non-steroidal anti-inflammatory drugs during gastric epithelial wound healing.  Digestion  2003  67(3):118-28  PubMed ID: 12853723
3799  Kinoshita Y1, Nakata H, Hassan S, Asahara M, Kawanami C, Matsushima Y, Naribayashi-Inomoto Y, Ping CY, Min D, Nakamura A, et al.  Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions.  Gastroenterology  1995  109(4):1068-77  PubMed ID: 7557071
3800  Kobayashi I, Kawano S, Tsuji S, Matsui H, Nakama A, Sawaoka H, Masuda E, Takei Y, Nagano K, Fusamoto H, Ohno T, Fukutomi H, Kamada T.  RGM1, a cell line derived from normal gastric mucosa of rat.  In Vitro Cell Dev Biol Anim  1996  32(5):259-61  PubMed ID: 8792153
3801  Miyazaki Y, Shinomura Y, Tsutsui S, Yasunaga Y, Zushi S, Higashiyama S, Taniguchi N, Matsuzawa Y.  Oxidative stress increases gene expression of heparin-binding EGF-like growth factor and amphiregulin in cultured rat gastric epithelial cells.  Biochem Biophys Res Commun  1996  226(2):542-6  PubMed ID: 8806670
3802  Miyazaki Y, Shinomura Y, Higashiyama S, Kanayama S, Higashimoto Y, Tsutsui S, Zushi S, Taniguchi N, Matsuzawa Y.  Heparin-binding EGF-like growth factor is an autocrine growth factor for rat gastric epithelial cells.  Biochem Biophys Res Commun  1996  223(1):36-41  PubMed ID: 8660375
3803  Shoji I, Aizaki H, Tani H, Ishii K, Chiba T, Saito I, Miyamura T, Matsuura Y.  Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors.  J Gen Virol  1997  78 ( Pt 10):2657-64  PubMed ID: 9349488
3804  Yoshikawa T, Naito Y, Masui K, Fujii T, Boku Y, Nakagawa S, Yoshida N, Kondo M.  Free radical-scavenging activity of Crassostera gigas extract (JCOE).  Biomed Pharmacother.   1997  51(8):328-32  PubMed ID: 9436525
3805  Furukawa O, Nakamura E, Okabe S.  Characterization of a novel cell damage model induced by acid and pepsin using rat gastric epithelial cells: protective effect of sucralfate.  J Gastroenterol Hepatol  1997  12(2):115-21  PubMed ID: 9083912
3807  Horie-Sakata K1, Shimada T, Hiraishi H, Terano A.  Role of cyclooxygenase 2 in hepatocyte growth factor-mediated gastric epithelial restitution.  J Clin Gastroenterol  1998  Suppl 1:S40-6  PubMed ID: 9872497
3809  Hassan S, Kinoshita Y, Okada A, Maekawa T, Fukui H, Chiba T.  Geranylgeranylacetone, an anti-ulcer drug, stimulates hexosamine production in a rat gastric mucosal cell line through binding to a specific cytosolic protein.  J Gastroenterol Hepatol.  1998  13(8):809-15  PubMed ID: 9736174
3810  Yuzuru Kubohara, Kenji Kabeya, Hirofumi Matsui, Koichi Ishikawa  Effects of DIF-1, an Anti-Tumor Agent Isolated from Dictyostelium discoideum, on Rat Gastric Mucosal RGM-1 and Leptomeningeal Cells  Zoological Science  2018  15(5):713-721 
3811  Sawaoka H, Tsuji S, Tsujii M, Gunawan ES, Kawai N, Sasaki Y, Hori M, Kawano S.  Involvement of cyclooxygenase-2 in proliferation and morphogenesis induced by transforming growth factor alpha in gastric epithelial cells.  Prostaglandins Leukot Essent Fatty Acids  1999  61(5):315-22.  PubMed ID: 10670694
3812  Pai R, Cover TL, Tarnawski AS.  Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells.  Biochem Biophys Res Commun  1999  262(1):245-50  PubMed ID: 10448099
3813  Maekawa T, Waki S, Okada A, Fukui H, Kinoshita Y, Chiba T.  Midkine gene expression in the healing process of gastric ulcer.  J Lab Clin Med  1999  133(4):349-52  PubMed ID: 10218765
3814  Hayashida Y, Nakata K, Ishikawa H, Taniguchi K, Migita K, Nakao K, Kato Y, Eguchi K.  Epidermal growth factor-mediated cell maturation and apoptosis in RGM-1 rat gastric mucosal cells.  Int J Mol Med  1999  4(3):253-6  PubMed ID: 10425274
3815  Miyazaki Y, Shinomura Y, Tsutsui S, Zushi S, Higashimoto Y, Kanayama S, Higashiyama S, Taniguchi N, Matsuzawa Y.  Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor.  Gastroenterology.  1999  116(1):78-89  PubMed ID: 9869605
3816  Noguchi H, Sakamoto C, Wada K, Akamatsu T, Uchida T, Tatsuguchi A, Matsui H, Fukui H, Fujimori T, Kasuga M.  Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells.  Gastroenterology  1999  117(5):1119-27  PubMed ID: 10535875
3817  Nakamura E, Takahashi S, Ishikawa M, Okabe S.  Inhibitory effect of macrophage-derived factors on the recovery of wounds induced in rat gastric epithelial monolayers.  Biochem Pharmacol  1999  58(7):1221-7  PubMed ID: 10484080
3818  Jones MK, Sasaki E, Halter F, Pai R, Nakamura T, Arakawa T, Kuroki T, Tarnawski AS.  HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: action mediated through the ERK2 signaling pathway.  FASEB J  1999  13(15):2186-94  PubMed ID: 10593866
3819  Ishikawa M, Tsukimi Y, Ogawa T, Okabe S.  Endogenous nitric oxide proves not to be involved in the inhibition by IL-1beta of TGF-alpha-stimulated proliferation of RGM1 cells.  J Physiol Pharmacol  2000  51(3):411-9  PubMed ID: 11016861
3820  Naito Y, Yoshikawa T, Boku Y, Fujii T, Masui Y, Tanaka Y, Fujita N, Yoshida N, Kondo M.  Protective role of intracellular glutathione against nitric oxide-induced necrosis in rat gastric mucosal cells.  Aliment Pharmacol Ther  2000  14 Suppl 1:145-52  PubMed ID: 10807416
3821  Suzuki H, Mori M, Seto K, Shibata F, Nagahashi S, Kawaguchi C, Suzuki M, Matsui H, Watanabe K, Miura S, Ishii H.  Rat CXC chemokine GRO/CINC-1 paradoxically stimulates the growth of gastric epithelial cells.  Aliment Pharmacol Ther  2000  14 Suppl 1:94-100.  PubMed ID: 10807410
3822  Akiba S, Hatazawa R, Ono K, Hayama M, Matsui H, Sato T.  Transforming growth factor-alpha stimulates prostaglandin generation through cytosolic phospholipase A(2) under the control of p11 in rat gastric epithelial cells.  Br J Pharmacol  2000  131(5):1004-10  PubMed ID: 11053223
3823  Pai R, Sasaki E, Tarnawski AS.  Helicobacter pylori vacuolating cytotoxin (VacA) alters cytoskeleton-associated proteins and interferes with re-epithelialization of wounded gastric epithelial monolayers.  Cell Biol Int  2000  24(5):291-301  PubMed ID: 10805963
3824  Yasuyoshi Fujii et al  Mitochondrial Cytochrome c Release and Caspase-3-Like Protease Activation During Indomethacin-Induced Apoptosis In Rat Gastric Mucosal Cells (44521)  Experimental Biology and Medicine  2000  224 
3825  Tominaga K, Higuchi K, Tsuno M, Watanabe T, Fujiwara Y, Kim S, Arakawa T, Iwao H, Kuroki T.  Induction of signal transduction pathways in rat gastric epithelial cells stimulated with interleukin-1beta.  Aliment Pharmacol Ther  2000  14 Suppl 1:101-8  PubMed ID: 10807411
3826  Shimada T, Hiraishi H, Terano A.  Hepatocyte growth factor protects gastric epithelial cells against ceramide-induced apoptosis through induction of cyclooxygenase-2.  Life Sci  2000  68(5):539-46  PubMed ID: 11197751
3827  Wang H, Tomikawa M, Jones MK, Pai R, Sarfeh IJ, Tarnawski AS.  Sequential expression of adrenomedullin and its receptor during gastric ulcer healing in rats.  Dig Dis Sci  2000  45(3):591-8  PubMed ID: 10749338
3828  Tominaga K, Arakawa T, Tsuno M, Kim S, Iwao H, Kuroki T.  Increased mitogen-activated protein kinase activities stimulated with interleukin-1-beta and mechanism(s) of the kinase signaling pathways in rat gastric epithelial cells.  Digestion  2000  61(1):30-8  PubMed ID: 10671772
3829  Houghton J, Macera-Bloch LS, Harrison L, Kim KH, Korah RM.  Tumor necrosis factor alpha and interleukin 1beta up-regulate gastric mucosal Fas antigen expression in Helicobacter pylori infection.  Infect Immun  2000  68:1189–1195 
3831  Fuji Y, Matsura T, Kai M, Kawasaki H, Yamada K.  Protection by polaprezinc, an anti-ulcer drug, against indomethacin-induced apoptosis in rat gastric mucosal cells.  Jpn J Pharmacol  2000  84(1):63-70  PubMed ID: 11043455
3832  Mizuno M, Okayama N, Kasugai K, Yoshida T, Miyata M, Nitta M, Kataoka H, Akita S, Joh T, Itoh M, Asai K, Kato T.  Acid stimulates E-cadherin surface expression on gastric epithelial cells to stabilize barrier functions via influx of calcium.  Eur J Gastroenterol Hepatol.  2001  13(2):127-36  PubMed ID: 11246611
3833  Dekigai H, Nakamura H, Bai J, Tanito M, Masutani H, Hirota K, Matsui H, Murakami M, Yodoi J.  Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes.  Free Radic Res  2001  35(1):23-30  PubMed ID: 11697114
3834  Miyake K, McNeil PL, Suzuki K, Tsunoda R, Sugai N.  An actin barrier to resealing.  J Cell Sci  2001  114(Pt 19):3487-94.  PubMed ID: 11682608
3835  Miyazaki Y, Hiraoka S, Tsutsui S, Kitamura S, Shinomura Y, Matsuzawa Y.  Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells.  Gastroenterology.  2001  120(1):108-16  PubMed ID: 11208719
3836  Akiba S1, Hatazawa R, Ono K, Kitatani K, Hayama M, Sato T.  Secretory phospholipase A2 mediates cooperative prostaglandin generation by growth factor and cytokine independently of preceding cytosolic phospholipase A2 expression in rat gastric epithelial cells.  J Biol Chem.   2001  276(24):21854-62  PubMed ID: 11274144
3837  Nakaya A, Wakabayashi H, Imamura L, Fukuta K, Makimoto S, Naganuma K, Orihara T, Minemura M, Shimizu Y, Nagasawa T, Hamazaki T, Watanabe A.  Helicobacter pylori alters n-6 fatty acid metabolism and prostaglandin E2 synthesis in rat gastric mucosal cells.  J Gastroenterol Hepatol  2001  16(11):1197-205  PubMed ID: 11903735
3838  Terano A, Sakata-Horie K, Shimada T, Hiraishi H, Yoshiura K, Yoneda M, Takahashi M, Fujimori T.  The role of cellular migration in the repair process of gastric epithelial cells.  Life Sci  2001  69(25-26):3083-9  PubMed ID: 11758833
3839  Pohle T, Becker JC, Markmann A, Lügering N, Pauels HG, Konturek JW, Domschke W.  Aspirin effects on gastric epithelial cell proliferation and cytokine expression.  Microsc Res Tech  2001  53(5):354-9  PubMed ID: 11376496
3841  Hiraoka S, Miyazaki Y, Kitamura S, Toyota M, Kiyohara T, Shinomura Y, Mukaida N, Matsuzawa Y.  Gastrin induces CXC chemokine expression in gastric epithelial cells through activation of NF-kappaB.  Am J Physiol Gastrointest Liver Physiol  2001  281(3):G735-42  PubMed ID: 11518686
3842  Giap AQ, Tarnawski A, Hoa NT, Akotia V, Ma TY.  NSAID inhibition of RGM1 gastric monolayer wound re-epithelialization: comparison of selective Cox-2 versus non-selective Cox inhibitors.  Life Sci  2002  70(25):3029-37  PubMed ID: 12138016
3843  Konda Y, Chiba T.  Rat gastric mucosal epithelial cell culture.  Methods Mol Biol  2002  188:17-25  PubMed ID: 11987542
3844  Naito Y, Handa O, Takagi T, Ishikawa T, Imamoto E, Nakagawa S, Yamaguchi T, Yoshida N, Matsui H, Yoshikawa T.  Ubiquitin-proteasome inhibitor enhances tumour necrosis factor-alpha-induced apoptosis in rat gastric epithelial cells.  Aliment Pharmacol Ther  2002  16 Suppl 2:59-66  PubMed ID: 11966525
3845  Shin VY, Liu ES, Koo MW, Luo JC, So WH, Cho CH.  Nicotine suppresses gastric wound repair via the inhibition of polyamine and K(+) channel expression.  Eur J Pharmacol  2002  444(1-2):115-21.  PubMed ID: 12191590
3846  Gao Y, Zhou S, Wen J, Huang M, Xu A.  Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin-induced lesions in the rat.  Life Sci  2002  72(6):731-45  PubMed ID: 12467913
3847  Hirose M, Miwa H, Kobayashi O, Oshida K, Misawa H, Kurosawa A, Watanabe S, Sato N.  Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway.  Aliment Pharmacol Ther.  2002  Suppl 2:83-9.  PubMed ID: 11966528
3848  Katsushi Nishihara Motoko Nakano Yoshihisa Nozawa Hirofusa Ajioka Atsuhiro Kanda Naosuke Matsuura Hidekazu Miyake  Effect of lafutidine on CGRP release from cultured rat dorsal root ganglion cells  InflammoPharmacology  2002  10:505–514 
3849  Shin VY, Liu ES, Koo MW, Wang JY, Matsui H, Cho CH.  Cigarette smoke extracts delay wound healing in the stomach: involvement of polyamine synthesis.  Exp Biol Med (Maywood)  2002  227(2):114-24  PubMed ID: 11815675
3850  Nakamura E, Hagen SJ.  Role of glutamine and arginase in protection against ammonia-induced cell death in gastric epithelial cells.  Am J Physiol Gastrointest Liver Physiol  2002  283(6):G1264-75  PubMed ID: 12388179
3851  Sasaki E, Tominaga K, Watanabe T, Fujiwara Y, Oshitani N, Matsumoto T, Higuchi K, Tarnawski AS, Arakawa T.  COX-2 is essential for EGF induction of cell proliferation in gastric RGM1 cells.  Dig Dis Sci  2003  48(12):2257-62  PubMed ID: 14714610
3852  Joh T, Takezono Y, Oshima T, Sasaki M, Seno K, Yokoyama Y, Ohara H, Nomura T, Alexander JS, Itoh M.  The protective effect of rebamipide on paracellular permeability of rat gastric epithelial cells.  Aliment Pharmacol Ther  2003  18 Suppl 1:133-8  PubMed ID: 12925151
3853  Kato S, Aihara E, Nakamura A, Xin H, Matsui H, Kohama K, Takeuchi K.  Expression of vanilloid receptors in rat gastric epithelial cells: role in cellular protection.  Biochem Pharmacol  2003  66(6):1115-21  PubMed ID: 12963499
3854  Honda K, Kato K, Dairaku N, Iijima K, Koike T, Imatani A, Sekine H, Ohara S, Matsui H, Shimosegawa T.  High levels of intracellular ATP prevent nitric oxide-induced apoptosis in rat gastric mucosal cells.  Int J Exp Pathol  2003  84(6):281-8  PubMed ID: 14748747
3855  Toyoda N, Gabazza EC, Inoue H, Araki K, Nakashima S, Oka S, Taguchi Y, Nakamura M, Suzuki Y, Taguchi O, Imoto I, Suzuki K, Adachi Y.  Expression and cytoprotective effect of protease-activated receptor-1 in gastric epithelial cells.  Scand J Gastroenterol  2003  38(3):253-9  PubMed ID: 12737439
3856  Becker JC, Hertel M, Markmann A, Shahin M, Werner S, Domschke W, Pohle T.  Dynamics and localization of activin A expression in rat gastric ulcers.  Scand J Gastroenterol  2003  38(3):260-7  PubMed ID: 12737440
3857  Aburatani S, Tashiro K, Savoie CJ, Nishizawa M, Hayashi K, Ito Y, Muta S, Yamamoto K, Ogawa M, Enomoto A, Masaki M, Watanabe S, Maki Y, Takahashi Y, Eguchi Y, Sakaki Y, Kuhara S.  Discovery of novel transcription control relationships with gene regulatory networks generated from multiple-disruption full genome expression libraries.  DNA Res  2003  10(1):1-8  PubMed ID: 12693549
3858  Takezono Y, Joh T, Oshima T, Suzuki H, Seno K, Yokoyama Y, Alexander JS, Itoh M.  Role of prostaglandins in maintaining gastric mucus-cell permeability against acid exposure.  J Lab Clin Med  2004  143(1):52-8  PubMed ID: 14749685
3859  Dairaku N, Kato K, Honda K, Koike T, Iijima K, Imatani A, Sekine H, Ohara S, Matsui H, Shimosegawa T.  Oligomycin and antimycin A prevent nitric oxide-induced apoptosis by blocking cytochrome C leakage.  J Lab Clin Med  2004  143(3):143-51  PubMed ID: 15007303
3860  Handa O, Naito Y, Takagi T, Shimozawa M, Kokura S, Yoshida N, Matsui H, Cepinskas G, Kvietys PR, Yoshikawa T.  Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB.  J Pharmacol Exp Ther  2004  309(2):670-6  PubMed ID: 14747614
3861  Chai J, Baatar D, Tarnawski A  Serum response factor promotes re-epithelialization and muscular structure restoration during gastric ulcer healing.  Gastroenterology.  2004  126(7):1809-18  PubMed ID: 15188176
3862  Tarnawski AS, Chai J, Pai R, Chiou SK.  Rebamipide activates genes encoding angiogenic growth factors and Cox2 and stimulates angiogenesis: a key to its ulcer healing action?  Dig Dis Sci  2004  49(2):202-9  PubMed ID: 15104358
3863  Katada K, Naito Y, Shimozawa M, Mizushima K, Kuroda M, Takagi T, Kokura S, Ichikawa H, Yoshida N, Matsui H, Yoshikawa T.  Gene expression analysis following hypoxia-reoxygenation in rat gastric epithelial cells using a high-density oligonucleotide array.  Redox Rep  2004  9(6):337-42  PubMed ID: 15720829
3864  Kubota Y, Kato K, Dairaku N, Koike T, Iijima K, Imatani A, Sekine H, Ohara S, Matsui H, Shimosegawa T.  Contribution of glutamine synthetase to ammonia-induced apoptosis in gastric mucosal cells.  Digestion  2004  69(3):140-8  PubMed ID: 15114044
3866  Bidel S, Mustonen H, Khalighi-Sikaroudi G, Lehtonen E, Puolakkainen P, Kiviluoto T, Kivilaakso E.  Effect of the ulcerogenic agents ethanol, acetylsalicylic acid and taurocholate on actin cytoskeleton and cell motility in cultured rat gastric mucosal cells.  World J Gastroenterol  2005  11(26):4032-9  PubMed ID: 15996028
3868  Yuji Naito et al  Rebamipide, a Gastroprotective Drug, Inhibits Indomethacin-Induced Apoptosis in Cultured Rat Gastric Mucosal Cells: Association with the Inhibition of Growth Arrest and DNA Damage-Induced 45α Expression  Digestive Diseases and Sciences  2005  5S:104–S112 
3869  Oyake J, Otaka M, Matsuhashi T, Jin M, Odashima M, Komatsu K, Wada I, Horikawa Y, Ohba R, Hatakeyama N, Itoh H, Watanabe S.  Over-expression of 70-kDa heat shock protein confers protection against monochloramine-induced gastric mucosal cell injury.  Life Sci  2006  79(3):300-5  PubMed ID: 16492383
3870  Wu WK, Li GR, Wong HP, Hui MK, Tai EK, Lam EK, Shin VY, Ye YN, Li P, Yang YH, Luo JC, Cho CH.  Involvement of Kv1.1 and Nav1.5 in proliferation of gastric epithelial cells.  J Cell Physiol  2006  207(2):437-44  PubMed ID: 16331678
3871  Katada K, Naito Y, Mizushima K, Takagi T, Handa O, Kokura S, Ichikawa H, Yoshida N, Matsui H, Yoshikawa T.  Gene expression profiles on hypoxia and reoxygenation in rat gastric epithelial cells: a high-density DNA microarray analysis.  Digestion  2006  73(2-3):89-100  PubMed ID: 16788290
3872  Shen 1, Sun WH, Xue QP, Wu J, Cheng YL, Ding GX, Fu HY, Tsuji S, Kawano S.  Influences of Helicobacter pylori on cyclooxygenase-2 expression and prostaglandinE2 synthesis in rat gastric epithelial cells in vitro.  J Gastroenterol Hepatic  2006  21(4):754-8.  PubMed ID: 16677165
3873  Nakagiri A, Fukushima K, Kato S, Takeuchi K.  Less irritative action of wine and Japanese sake in rat stomachs: a comparative study with ethanol.  Dig Dis Sci  2006  51(2):289-97  PubMed ID: 1653467
3874  M. OTAKA T. MATSUHASHI M. ODASHIMA H. ITOH M. JIN I. WADA K. KOMATSU Y. HORIKAWA R. OHBA J. OYAKE N. HATAKEYAMA S. WATANABE  Enhancement of cytoprotective ability and cell restoration in 70‐kDa heat shock protein gene‐transfected rat gastric mucosal cells  Aliment Pharmacol Ther   2006  24:272–277 
3875  Gower WR Jr1, Carter GM, McAfee Q, Solivan SM.  Identification, regulation and anti-proliferative role of the NPR-C receptor in gastric epithelial cells.  Mol Cell Biochem  2006  293(1-2):103-18  PubMed ID: 16786190
3876  Becker JC, Grosser N, Waltke C, Schulz S, Erdmann K, Domschke W, Schröder H, Pohle T.  Beyond gastric acid reduction: proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells.  Biochem Biophys Res Commun  2006  345(3):1014-21  PubMed ID: 1671279
3778  Yonezawa D, Sekiguchi F, Miyamoto M, Taniguchi E, Honjo M, Masuko T, Nishikawa H, Kawabata A.  A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium.  Toxicology  2007  241(1-2):11-8  PubMed ID: 17825973
3878  Tan A, Nakamura H, Kondo N, Tanito M, Kwon YW, Ahsan MK, Matsui H, Narita M, Yodoi J.  Thioredoxin-1 attenuates indomethacin-induced gastric mucosal injury in mice.  Free Radic Res  2007  41(8):861-9  PubMed ID: 17654042
3881  Fu HY, Asahi K, Hayashi Y, Eguchi H, Murata H, Tsujii M, Tsuji S, Azuma T, Kawano S.  East Asian-type Helicobacter pylori cytotoxin-associated gene A protein has a more significant effect on growth of rat gastric mucosal cells than the Western type.  J Gastroenterol Hepatol  2007  22(3):355-62  PubMed ID: 17295767
3882  Wu WK, Law PT, Wong HP, Lam EK, Tai EK, Shin VY, Cho CH.  Shift of homeostasis from parenchymal regeneration to fibroblast proliferation induced by lipopolysaccharide-activated macrophages in gastric mucosal healing in vitro.  Wound Repair Regen  2007  15(2):221-6  PubMed ID: 17352754
3884  Odashima M, Otaka M, Matsuhashi T, Jin M, Horikawa Y, Ohba R, Itoh H, Watanabe S.  Mechanical strain stress suppresses expression of HSP70 and wound restoration in gastric mucosal cells.  Dig Dis Sci  2007  52(11):3087-91  PubMed ID: 17393320
3885  Nguyen T, Chai J, Li A, Akahoshi T, Tanigawa T, Tarnawski AS.  Novel roles of local insulin-like growth factor-1 activation in gastric ulcer healing: promotes actin polymerization, cell proliferation, re-epithelialization, and induces cyclooxygenase-2 in a phosphatidylinositol 3-kinase-dependent manner.  Am J Pathol  2007  170(4):1219-28  PubMed ID: 17392162
3886  Matsuhashi T, Otaka M, Odashima M, Jin M, Komatsu K, Wada I, Horikawa Y, Ohba R, Oyake J, Hatakeyama N, Watanabe S.  Protective effect of a novel rice extract against ethanol-induced gastric mucosal injury in rat.  Dig Dis Sci  2007  52(2):434-41  PubMed ID: 17216574
3887  Nylander-Koski O, Kiviluoto T, Puolakkainen P, Kivilaakso E, Mustonen H.  The effect of nitric oxide, growth factors, and estrogen on gastric cell migration.  J Surg Res  2007  143(2):230-7  PubMed ID: 17950324
3889  Suzuki T, Yoshida N, Nakabe N, Isozaki Y, Kajikawa H, Takagi T, Handa O, Kokura S, Ichikawa H, Naito Y, Matsui H, Yoshikawa T.  Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution.  J Pharmacol Sci  2008  106(3):469-77  PubMed ID: 18360096
3890  Wu WK1, Li GR, Wong TM, Wang JY, Yu L, Cho CH.  Involvement of voltage-gated K+ and Na+ channels in gastric epithelial cell migration.  Mol Cell Biochem  2008  308(1-2):219-26  PubMed ID: 17978865
3891  Li H, Cai X, Fan X, Moquin B, Stoicov C, Houghton J.  Fas Ag-FasL coupling leads to ERK1/2-mediated proliferation of gastric mucosal cells.  Am J Physiol Gastrointest Liver Physiol  2008  294(1):G263-75  PubMed ID: 17991709
3892  Ng KM, Cho CH, Chang FY, Luo JC, Lin HC, Lin HY, Chi CW, Lee SD.  Omeprazole promotes gastric epithelial cell migration.  J Pharm Pharmacol  2008  60(5):655-60  PubMed ID: 18416943
3893  Jones MK1, Padilla OR, Webb NA, Norng M.  The anti-apoptosis protein, survivin, mediates gastric epithelial cell cytoprotection against ethanol-induced injury via activation of the p34(cdc2) cyclin-dependent kinase.  J Cell Physiol  2008  215(3):750-64  PubMed ID: 18181150
3896  Alli AA1, Gower WR Jr.  The C type natriuretic peptide receptor tethers AHNAK1 at the plasma membrane to potentiate arachidonic acid-induced calcium mobilization.  Am J Physiol Cell Physiol.  2009  297(5):C1157-67  PubMed ID: 19710363
3897  Olaleye SB, Wu KK, Cho CH.  Catecholamines inhibit gastric epithelial [RGM-1] cell proliferation via β adrenoceptors.  Niger J Physiol Sci.   2010  25(1):5-16  PubMed ID: 22314897
3899  Chai JY, Modak C, Mouazzen W, Narvaez R, Pham J.  Epithelial or mesenchymal: Where to draw the line?  Biosci Trends  2010  4(3):130-42  PubMed ID: 20592463
3907  Tatsugami M, Ito M, Tanaka S, Yoshihara M, Matsui H, Haruma K, Chayama K.  Bile acid promotes intestinal metaplasia and gastric carcinogenesis.  Cancer Epidemiol Biomarkers Prev  2012  21(11):2101-7  PubMed ID: 23010643
3910  Luo JC, Huo TI, Hou MC, Lin HY, Li CP, Lin HC, Chang FY, Lee FY.  Clopidogrel delays gastric ulcer healing in rats.  Eur J Pharmacol  2012  15;695(1-3):112-9  PubMed ID: 22975710
3911  Suemasu S, Yamakawa N, Ishihara T, Asano T, Tahara K, Tanaka K, Matsui H, Okamoto Y, Otsuka M, Takeuchi K, Suzuki H, Mizushima T.  Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity.  Biochem Pharmacol  2012  84(11):1470-81  PubMed ID: 23022227
3918  Saito R1, Tamura M1, Matsui H1, Nagano Y1, Suzuki H1, Kaneko T1, Mizokami Y1, Hyodo I1.  Qing Dai attenuates nonsteroidal anti-inflammatory drug-induced mitochondrial reactive oxygen species in gastrointestinal epithelial cells.  J Clin Biochem Nutr  2015  56(1):8-14  PubMed ID: 25678747
3919  Tatsunobu MatsuiM.S. et al  Histidine deficiency attenuates cell viability in rat intestinal epithelial cells by apoptosis via mitochondrial dysfunction  Journal of Nutrition & Intermediary Metabolism  2017  8:21-28 
3920  Paehler Vor der Nolte A, Chodisetti G, Yuan Z, Busch F, Riederer B, Luo M, Yu Y, Menon MB, Schneider A, Stripecke R, Nikolovska K, Yeruva S, Seidler U.  Na+ /H+ exchanger NHE1 and NHE2 have opposite effects on migration velocity in rat gastric surface cells.  J Cell Physiol.  2017  232(7):1669-1680  PubMed ID: 28019659



Back Back Return Top Page