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RCB0558 : LLC  update : 2018/07/31
CommentHighly metastatic and drug-resistant mouse tumor. Application consideration
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Sugimoto, Yoshikazu
Originator Sugimoto, Y. (in vitro)
Year of deposit 1990
Another name Lewis lung carcinoma
Animal mouse < Mammals
Tissue lung
Metastastatic ability Yes
Classification cancer
Lifespan infinite
Morphology other
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM (low glucose) + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 4-6 split
SC frequency Subculture : 1-2 times/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP (mouse) OK
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 2
User's Publication 33


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Reference
1371  Bertram, J S, Janik P  Establishment of a cloned line of Lewis Lung Carcinoma cells adapted to cell culture.  Cancer Lett  1980  11:63-73  PubMed ID: 7226139
4767  Janik P, Assaf A, Bertram JS.  Inhibition of growth of primary and metastatic Lewis lung carcinoma cells by the phosphodiesterase inhibitor isobutylmethylxanthine.  Cancer Res  1980  40(6):1950-4  PubMed ID: 6154533

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User's Publication
3290  Nakamura, Kazuki, Yoshikawa, Noriko, Yamaguchi, Yu, Kagota, Satomi, Shinozuka, Kazumasa, Kunitomo, Masaru  Antitumor effect of cordycepin (3'-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation.  Anticancer Res  2006  26:43-7  PubMed ID: 16475677
2636  Fujisawa H  Inhibitory role of neutrophils on influenza virus multiplication in the lungs of mice.  Microbiol Immunol  2001  45:679-88  PubMed ID: 11762750
2199  Sumimoto H, Tani K, Nakazaki Y, Tanabe T, Hibino H, Hamada H, Azuma M, Asano S  GM-CSF and B7-1 (CD80) co-stimulatory signals co-operate in the induction of effective anti-tumor immunity in syngeneic mice.  Int J Cancer  1997  73:556-61  PubMed ID: 9389572
2270  Sumimoto H, Tani K, Nakazaki Y, Tanabe T, Hibino H, Wu, M S, Izawa K, Hamada H, Asano S  Superiority of interleukin-12 taransduced murine lung cancer cells to GM-CSF or B7-1 (CD80) transfectants for therapeutic antitumor immunity in syngeneic immunocompetent mice  Cancer Gene Therapy  1998  5:29-37  PubMed ID: 9476964
2355  Nakamura K, Yamaguchi Y, Kagota S, Kwon, Y M, Shinozuka K, Kunitomo M  Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice.  Jpn J Pharmacol  1999  79:335-41  PubMed ID: 10230862
7088  Mukai H, Muramatsu A, Mashud R, Kubouchi K, Tsujimoto S, Hongu T, Kanaho Y, Tsubaki M, Nishida S, Shioi G, Danno S, Mehruba M, Satoh R, Sugiura R.  PKN3 is the major regulator of angiogenesis and tumor metastasis in mice.  Sci Rep  2016  6:18979  PubMed ID: 26742562
7872  Hara K, Kasahara E, Takahashi N, Konishi M, Inoue J, Jikumaru M, Kubo S, Okamura H, Sato E, Inoue M.  Mitochondria determine the efficacy of anticancer agents that interact with DNA but not the cytoskeleton.  J. Pharmacol. Exp. Ther.  2011  337:838-45  PubMed ID: 21421738
8218  Yin X, Yan X, Yang Q, Cao H, Liang H.  Antitumor mechanism of recombinant murine interleukin-12 vaccine.  Cancer Biother. Radiopharm.  2010  25:263-8  PubMed ID: 20578831
8326  Izukuri K, Suzuki K, Yajima N, Ozawa S, Ito S, Kubota E, Hata R.  Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected]  Transgenic Res.  2010  19:1109-17  PubMed ID: 20333465
8438  Yin XL, Yan X, Wen M, Peng ZP, Li SL.  Synergistic antitumor effects of 131I-LC-1 IgM and IL-12 vaccine on Lewis lung carcinoma.  Int. Immunopharmacol.  2009  10:284-9  PubMed ID: 19951748
8763  Jung YK, Jin JS, Jeong JH, Kim HN, Park NR, Choi JY.  DICAM, a novel dual immunoglobulin domain containing cell adhesion molecule interacts with alphavbeta3 integrin.  J. Cell. Physiol.  2008  216:603-14  PubMed ID: 18366072
8812  Yamamura H, Hirano N, Koyama H, Nishizawa Y, Takahashi K.  Loss of smooth muscle calponin results in impaired blood vessel maturation in the tumor-host microenvironment.  Cancer Sci.  2007  98:757-63  PubMed ID: 17391313
9613  Wang X, Li X, Yoshiyuki K, Watanabe Y, Sogo Y, Ohno T, Tsuji NM, Ito A.  Comprehensive Mechanism Analysis of Mesoporous-Silica-Nanoparticle-Induced Cancer Immunotherapy.  Adv Healthc Mater  2016  5:1169-76  PubMed ID: 26987867
9643  Naito H, Wakabayashi T, Kidoya H, Muramatsu F, Takara K, Eino D, Yamane K, Iba T, Takakura N.  Endothelial Side Population Cells Contribute to Tumor Angiogenesis and Antiangiogenic Drug Resistance.  Cancer Res.  2016  76:3200-10  PubMed ID: 27197162
9904  Hanaoka Y, Yamaguchi Y, Yamamoto H, Ishii M, Nagase T, Kurihara H, Akishita M, Ouchi Y.  In Vitro and In Vivo Anticancer Activity of Human β-Defensin-3 and Its Mouse Homolog.  Anticancer Res.  2016  36:5999-6004  PubMed ID: 27793926
10609  Omori K, Morikawa T, Kunita A, Nakamura T, Aritake K, Urade Y, Fukayama M, Murata T.  Lipocalin-type prostaglandin D synthase-derived PGD2 attenuates malignant properties of tumor endothelial cells.  J. Pathol.  2018  244:84-96  PubMed ID: 29124765
10663  Okuma A, Hanyu A, Watanabe S, Hara E.  p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis.  Nat Commun  2017  8:2050  PubMed ID: 29234059
10811  Yamakawa D, Jia W, Kidoya H, Hosojima S, Torigata M, Zhang L, Takakura N.  Visualization of Proliferative Vascular Endothelial Cells in Tumors in Vivo by Imaging Their Partner of Sld5-1 Promoter Activity.  Am. J. Pathol.  2018  188:1300-1314  PubMed ID: 29650228
4047  Naito H, Iba T, Wakabayashi T, Tai-Nagara I, Suehiro JI, Jia W, Eino D, Sakimoto S, Muramatsu F, Kidoya H, Sakurai H, Satoh T, Akira S, Kubota Y, Takakura N.  TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity  Dev Cell  2019  48(2):151-166  PubMed ID: 30639056
11311  Umakoshi M, Takahashi S, Itoh G, Kuriyama S, Sasaki Y, Yanagihara K, Yashiro M, Maeda D, Goto A, Tanaka M.  Macrophage-mediated transfer of cancer-derived components to stromal cells contributes to establishment of a pro-tumor microenvironment.  Oncogene  2019    PubMed ID: 30459356
11310  Wang Y, Zenkoh J, Gerelchuluun A, Sun L, Cai S, Li X, Tsuboi K.  Administration of Dendritic Cells and Anti-PD-1 Antibody Converts X-ray Irradiated Tumors Into Effective In situ Vaccines.  Int. J. Radiat. Oncol. Biol. Phys.  2019    PubMed ID: 30458232
5370  Hamada K, Mikasa K, Yunou Y, Kurioka T, Majima T, Narita N, Kita E.  Adjuvant effect of clarithromycin on chemotherapy for murine lung cancer.  Chemotherapy  2000  46(1):49-61  PubMed ID: 10601798
5373  Kawashiri T, Egashira N, Itoh Y, Shimazoe T, Ikegami Y, Yano T, Yoshimura M, Oishi R.  Neurotropin reverses paclitaxel-induced neuropathy without affecting anti-tumour efficacy.  Eur J Cancer  2009  45(1):154-63  PubMed ID: 19027286
5377  Mizumoto S, Takahashi J, Sugahara K.  Receptor for advanced glycation end products (RAGE) functions as receptor for specific sulfated glycosaminoglycans, and anti-RAGE antibody or sulfated glycosaminoglycans delivered in vivo inhibit pulmonary metastasis of tumor cells.  J Biol Chem  2012  287(23):18985-94  PubMed ID: 22493510
5392  Tsutsumi K, Kaname T1, Shiraishi H1, Kawashiri T1, Egashira N.  Polaprezinc reduces paclitaxel-induced peripheral neuropathy in rats without affecting anti-tumor activity.  J Pharmacol Sci  2016  131(2):146-9  PubMed ID: 27262900
3567  Yoshikawa N, Nakamura K, Yamaguchi Y, Kagota S, Shinozuka K, Kunitomo M.  Reinforcement of antitumor effect of Cordyceps sinensis by 2'-deoxycoformycin, an adenosine deaminase inhibitor.  In Vivo  2007  21(2):291-5  PubMed ID: 17436579
3952  Akatsu T, Ono K, Katayama Y, Tamura T, Nishikawa M, Kugai N, Yamamoto M, Nagata N.  The mouse mammary tumor cell line, MMT060562, produces prostaglandin E2 and leukemia inhibitory factor and supports osteoclast formation in vitro via a stromal cell-dependent pathway.  J Bone Miner Res  1998  13(3):400-8  PubMed ID: 9525340
6261  Matsui H, Ohnishi J, Takahashi T.  Proteolytic activation of tissue-type plasminogen activator by the culture media of mouse cancer cells.  Zoolog Sci  1998  15(4):499-505  PubMed ID: 18462028
6266  Matsui H, Kimura A, Yamashiki N, Moriyama A, Kaya M, Yoshida I, Takagi N, Takahashi T.  Molecular and biochemical characterization of a serine proteinase predominantly expressed in the medulla oblongata and cerebellar white matter of mouse brain.  J Biol Chem  2000  275(15):11050-7  PubMed ID: 10753908
6293  Imai N, Hashimoto T, Kihara M, Yoshida S, Kawana I, Yazawa T, Kitamura H, Umemura S.  Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis.  Lab Invest  2007  87(2):189-98  PubMed ID: 17318197
6338  Yu R, Zheng Y, Lucas MB, Tong YG.  Elusive liver factor that causes pancreatic α cell hyperplasia: A review of literature.  World J Gastrointest Pathophysiol  2015  6(4):131-9  PubMed ID: 26600971
6349  Ponzio G, Rezzonico R, Bourget I, Allan R, Nottet N, Popa A, Magnone V, Rios G, Mari B, Barbry P.  A new long noncoding RNA (lncRNA) is induced in cutaneous squamous cell carcinoma and down-regulates several anticancer and cell differentiation genes in mouse.  J Biol Chem.   2017  292(30):12483-12495  PubMed ID: 28596382
3336  Kuang M, Liu, S Q, Saijo K, Uchimura E, Huang L, Leong, K W, Lu, M D, Huang, J F, Ohno T  Microwave tumour coagulation plus in situ treatment with cytokine-microparticles: induction of potent anti-residual tumour immunity.  Int J Hyperthermia  2005  21:247-57  PubMed ID: 16019851



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