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RCB0555 : GCIY  update : 2018/07/06
CommentStomach cancer (Borrmann IV). Mucin, CA19-9, CEA, alphafetoprotein positive Cell growth is slow.
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Nozue, Mutsumi
Originator Nozue, Mutsumi
Year of deposit 1990
Original cell TKG0405
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Female
Tissue stomach
Case history adenocarcinoma (Borrmann IV)
Metastastatic ability Yes
Classification cancer
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 15% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/1-2 weeks, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 56-122(50) : /59(4),60(11),61(19),62(3),63(2),66(1)/
Images
deposit info
lot info
Reference information Reference 3
User's Publication 39


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Reference
1324  [Establishment and characterization of a human scirrhus type gastric cancer cell line, GCIY, producing CA19-9]  Nozue M, Nishida M, Todoroki T, Iwasaki Y  Hum Cell  1991  4:71-5  PubMed ID: 1653599
4757  Selection of three out of 24 anti-cancer agents in poorly-differentiated gastric cancer cell lines, evaluated by the AUC/delta IC50 ratio.  Nozue M, Nishida M, Todoroki T, Fukao K, Tanaka M.  Anticancer Drugs  1995  6(2):291-302  PubMed ID: 7795277
4758  5-fu dose-dependency in mtx/s-fu sequential therapy assessed by in-vitro assay using gastric-cancer cell-lines.  Nozue M, Todoroki T, Fukao K.  Oncol Rep  1995  2(5):737-40  PubMed ID: 21597807

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User's Publication
2063  Radioimmunoimaging of Human Colorectal Adenocarcinoma with a Monoclonal Antibody, NCC-CO-411, Against a Human Carcinoembryonic Antigen  Wang, D., S., Ueno, Y., Oyamada, H., and Kojima, S.  Antibody, Immunoconjugates, and Radiopharmaceuticals  1995  8:129-143 
2807  Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.  Shida D, Kitayama J, Yamaguchi H, Hama K, Aoki J, Arai H, Yamashita H, Mori K, Sako A, Konishi T, Watanabe T, Sakai T, Suzuki R, Ohta H, Takuwa Y, Nagawa H  Exp Cell Res  2004  301:168-78  PubMed ID: 15530853
3077  Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T  Mol Cancer Ther  2005  4:399-412  PubMed ID: 15767549
2062  Accumulation of NCC-CO-411 monoclonal antibody in human colorectal adenocarcinoma through binding of the released carcinoembryonic antigen in nude mice.  Wang, D S, Ueno Y, Oyamada H, Kojima S  Biol Pharm Bull  1996  19:915-21  PubMed ID: 8839961
2177  Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines  Tamura G, Sakata K, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R  Jpn J Cancer Res  1996  87:1153-1159  PubMed ID: 9045944
7357  Efficient capturing of circulating tumor cells using a magnetic capture column and a size-selective filter.  Yamamoto S, Fei J, Okochi M, Shimizu K, Yusa A, Kondo N, Iwata H, Nakanishi H, Honda H.  Bioprocess Biosyst Eng  2015  38:1693-704  PubMed ID: 25964183
8118  Bifidobacterium bifidum BF-1 suppresses Helicobacter pylori-induced genes in human epithelial cells.  Shirasawa Y, Shibahara-Sone H, Iino T, Ishikawa F.  J. Dairy Sci.  2010  93:4526-34  PubMed ID: 20854986
9594  Living cells of probiotic Bifidobacterium bifidum YIT 10347 detected on gastric mucosa in humans.  Shibahara-Sone H, Gomi A, Iino T, Kano M, Nonaka C, Watanabe O, Miyazaki K, Ohkusa T.  Benef Microbes  2016  7:319-26  PubMed ID: 26925600
9928  Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.  Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S, Esteller M.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E7535-E7544  PubMed ID: 27821766
10277  Rare cell isolation and recovery on open-channel microfluidic chip.  Masuda T, Song W, Nakanishi H, Lei W, Noor AM, Arai F.  PLoS ONE  2017  12:e0174937  PubMed ID: 28426707
10662  Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells.  Miyamoto S, Nagamura Y, Nakabo A, Okabe A, Yanagihara K, Fukami K, Sakai R, Yamaguchi H.  Biochem. Biophys. Res. Commun.  2018  495:1942-1947  PubMed ID: 29247652
4049  Dietary intake of pyrolyzed deketene curcumin inhibits gastric carcinogenesis  Taichi Yoshida, Takashi Maruyama, Masatomo Miura, Masahiro Inoue, Koji Fukuda, Kazuhiro Shimazu, Daiki Taguchi, Hiroaki Kanda, Masanobu Oshima, Yoshiharu Iwabuchi, Hiroyuki Shibata  Journal of Functional Foods  2018  50:192-200 
4188  High stromal transforming growth factor β-induced expression is a novel marker of progression and poor prognosis in gastric cancer.  Suzuki M, Yokobori T, Gombodorj N, Yashiro M, Turtoi A, Handa T, Ogata K, Oyama T, Shirabe K, Kuwano H.  J Surg Oncol  2018    PubMed ID: 30260476
4380  Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer.  Yoshioka T, Shien K, Namba K, Torigoe H, Sato H, Tomida S, Yamamoto H, Asano H, Soh J, Tsukuda K, Nagasaka T, Fujiwara T, Toyooka S.  Cancer Sci.  2018  109(4):1166-1176  PubMed ID: 29465762
5397  TNF-alpha promotes progression of peritoneal metastasis as demonstrated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line.  Mochizuki Y, Nakanishi H, Kodera Y, Ito S, Yamamura Y, Kato T, Hibi K, Akiyama S, Nakao A, Tatematsu M.  Clin Exp Metastasis  2004  21(1):39-47.  PubMed ID: 15065601
3733  Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer.  Nishikawaji T, Akiyama Y, Shimada S, Kojima K, Kawano T, Eishi Y, Yuasa Y, Tanaka S.  Oncotarget  2016  7(41):67251-67265  PubMed ID: 27572307
3763  Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells.  Takaishi S, Sawada M, Morita Y, Seno H, Fukuzawa H, Chiba T.  Biochem Biophys Res Commun  2000  19;267(2):658-62  PubMed ID: 10631118
3796  Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines.  Fukami T, Fukuhara H, Kuramochi M, Maruyama T, Isogai K, Sakamoto M, Takamoto S, Murakami Y.  Int J Cancer  2003  107(1):53-9  PubMed ID: 12925956
5811  Enhanced expression of semaphorin 3E is involved in the gastric cancer development.  Maejima R et al  Int J Oncol  2016  49(3):887-94  PubMed ID: 27572291
5825  New whole-body multimodality imaging of gastric cancer peritoneal metastasis combining fluorescence imaging with ICG-labeled antibody and MRI in mice.  Ito A, Ito Y, Matsushima S, Tsuchida D, Ogasawara M, Hasegawa J, Misawa K, Kondo E, Kaneda N, Nakanishi H.  Gastric Cancer  2014  17(3):497-507  PubMed ID: 24288123
5845  Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.  Konno-Shimizu M1, Yamamichi N, Inada K, Kageyama-Yahara N, Shiogama K, Takahashi Y, Asada-Hirayama I, Yamamichi-Nishina M, Nakayama C, Ono S, Kodashima S, Fujishiro M, Tsutsumi Y, Ichinose M, Koike K.  PLoS One  2013  8(2):e56766  PubMed ID: 23451082
5847  Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer.  Zhao L, Yasumoto K, Kawashima A, Nakagawa T, Takeuchi S, Yamada T, Matsumoto K, Yonekura K, Yoshie O, Yano S.  Cancer Sci  2013  104(12):1640-6  PubMed ID: 24118504
5853  Noninvasive and real-time fluorescence imaging of peritoneal metastasis in nude mice.  Nakanishi H, Ito S, Matsui M, Ito Y, Misawa K, Kodera Y.  Methods Mol Biol  2012  872:85-95  PubMed ID: 22700405
5856  High mannose-binding antiviral lectin PFL from Pseudomonas fluorescens Pf0-1 promotes cell death of gastric cancer cell MKN28 via interaction with α2-integrin.  Sato Y, Morimoto K, Kubo T, Yanagihara K, Seyama T.  PLoS One  2012  7(9):e45922  PubMed ID: 23029318
5899  Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis.  Yokoyama H, Ikehara Y, Kodera Y, Ikehara S, Yatabe Y, Mochizuki Y, Koike M, Fujiwara M, Nakao A, Tatematsu M, Nakanishi H.  Br J Cancer  2006  95(11):1504-13  PubMed ID: 17088902
5906  Induction of cytotoxic T lymphocytes against human cancer cell lines using dendritic cell-tumor cell hybrids generated by a newly developed electrofusion technique.  Imura K, Ueda Y, Hayashi T, Itoh T, Shimizu K, Tamai H, Yano Y, Naito K, Kohara J, Nakane K, Matsuura Y, Takeda A, Takeda T, Kawai K, Yamagishi H.  Int J Oncol  2006  29(3):531-9  PubMed ID: 16865268
5910  Evaluation of chemosensitivity of micrometastases with green fluorescent protein gene-tagged tumor models in mice.  Nakanishi H, Ito S, Mochizuki Y, Tatematsu M.  Methods Mol Med  2005  2005;111:351-62  PubMed ID: 15911990
5931  Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer.  Terashima M, Fujiwara H, Takagane A, Abe K, Irinoda T, Nakaya T, Yonezawa H, Oyama K, Saito K, Kanzaki N, Ohtani S, Nemoto T, Hoshino Y, Kogure M, Gotoh M.  Gastric Cancer  2003  6 Suppl 1:71-81.  PubMed ID: 12775024
5932  Superior antitumour activity of S-1 in tumours with a high dihydropyrimidine dehydrogenase activity.  Fujiwara 1, Terashima M, Irinoda T, Takagane A, Abe K, Nakaya T, Yonezawa H, Oyama K, Takahashi M, Saito K, Takechi T, Fukushima M, Shirasaka T.  Eur J Cancer  2003  39(16):2387-94  PubMed ID: 14556932
5935  Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.  Dan S, Shirakawa M, Mukai Y, Yoshida Y, Yamazaki K, Kawaguchi T, Matsuura M, Nakamura Y, Yamori T.  Cancer Sci  2003  94(12):1074-82  PubMed ID: 14662023
5941  Quantitative measurement of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level in gastric cancer by real-time RT-PCR.  Fujiwara H, Terashima M, Irinoda T, Takagane A, Abe K, Kashiwaba M, Oyama K, Takahashi M, Maesawa C, Saito K, Takechi T, Fukushima M.  Jpn J Cancer Res  2002  93(12):1342-50  PubMed ID: 12495474
5973  Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines.  Tamura G, Sakata K, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R.  Genes Chromosomes Cancer  1997  20(1):98-102  PubMed ID: 9290961
5302  Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.  Yamaguchi H, Takanashi M, Yoshida N, Ito Y, Kamata R, Fukami K, Yanagihara K, Sakai R.  Cancer Sci  2014  105(5):528-36  PubMed ID: 24612061
6075  Establishment and characterization of novel gastric signet-ring cell and non signet-ring cell poorly differentiated adenocarcinoma cell lines with low and high malignant potential.  Murakami H, Nakanishi H, Tanaka H, Ito S, Misawa K, Ito Y, Ikehara Y, Kondo E, Kodera Y.  Gastric Cancer  2013  16(1):74-83  PubMed ID: 22450770
6386  Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth.  Oji Y, Ogawa H, Tamaki H, Oka Y, Tsuboi A, Kim EH, Soma T, Tatekawa T, Kawakami M, Asada M, Kishimoto T, Sugiyama H.  Jpn J Cancer Res  1999  90(2):194-204  PubMed ID: 10189890
6407  Gastrin receptor gene expression in several human carcinomas.  Matsushima Y, Kinoshita Y, Nakata H, Inomoto-Naribayashi Y, Asahara M, Kawanami C, Nakamura A, Ito M, Matsui T, Fujiwara T, et al.  Jpn J Cancer Res  1994  85(8):819-24  PubMed ID: 7928627
6409  Expression of protooncogene c-kit and its ligand stem cell factor (SCF) in gastric carcinoma cell lines.  Hassan S, Kinoshita Y, Kawanami C, Kishi K, Matsushima Y, Ohashi A, Funasaka Y, Okada A, Maekawa T, He-Yao W, Chiba T.  Dig Dis Sci  1998  43(1):8-14  PubMed ID: 9508539
11505  Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.  Kageyama-Yahara N, Yamamichi N, Takahashi Y, Takeuchi C, Matsumoto Y, Sakaguchi Y, Koike K.  Biochem Biophys Rep  2019  18:100632  PubMed ID: 30993217
6410  Is parainfluenza virus a threatening virus for human cancer cell lines?  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309



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