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RCB0535 : RAW 264  update : 2018/07/31
CommentBuck-up culture of ECA8510291 . Mouse leukemic monocyte. Abelson leukemia virus induced. Application consideration
Comment from the depositor
Restriction (Category)a
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor ECACC
Year of deposit 1990
Animal mouse < Mammals
Strain name BALB/c
Tissue leukemic monocyte
Classification transformed
History overseas, ECACC
Lifespan infinite
Morphology other
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 10% FBS + 0.1mM NEAA
Antibiotics Free
Passage method 0.25% trypsin + 0.02% EDTA
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP (mouse) OK
Images
deposit info
lot info
Reference information Reference 1
User's Publication 238


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Reference
716  Ralph P, Nakoinz I  Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS.  J Immunol  1977  119:950-54  PubMed ID: 894031

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User's Publication
2890  Ito T, Morimatsu M, Oonuma T, Shiina T, Kitamura H, Syuto B  Transcriptional regulation of the MAIL gene in LPS-stimulated RAW264 mouse macrophages.  Gene  2004  342:137-43  PubMed ID: 15527973
2903  Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K  Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation.  Biochem Biophys Res Commun  2005  332:793-9  PubMed ID: 15907790
2904  Itoh CE, Kizaki T, Hitomi Y, Hanawa T, Kamiya S, Ookawara T, Suzuki K, Izawa T, Saitoh D, Haga S, Ohno H  Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.  Biochem Biophys Res Commun  2004  322:979-84  PubMed ID: 15336560
1645  Tanida N, Ohno N, Adachi Y, Matsuura M, Nakano M, Kiso M, Hasegawa A, Yadomae T  Modification of Immunopharmacologicaln Activities of Synthetic Monosaccharide Lipid A Analogue, GLA60, by Lysozyme  J Biochem (Tokyo)  1992  112:616-623 
2366  Yamashita M, Niki H, Yamada M, Mue S, Ohuchi K  Induction of nitric oxide synthase by lipopolysaccharide and its inhibition by auranofin in RAW 264.7 cells.  Eur J Pharmacol  1997  338:151-8 
2423  Okada S, Zhang H, Hatano M, Tokuhisa T  A physiologic role of Bcl-xL induced in activated macrophages.  J Immunol  1998  160:2590-6 
3224  Abe-Dohmae S, Suzuki S, Wada Y, Aburatani H, Vance, D E, Yokoyama S  Characterization of apolipoprotein-mediated HDL generation induced by cAMP in a murine macrophage cell line.  Biochemistry  2000  39:11092-9 
3225  Suzuki S, Abe-Dohmae S, Fukutomi T, Ito S, Itoh M, Yokoyama S  Enhancement of the cAMP-induced apolipoprotein-mediated cellular lipid release by calmodulin inhibitors W7 and W5 from RAW 264 mouse macrophage cell line cells.  J Cardiovasc Pharmacol  2000  36:609-16 
2504  Haruta I, Kato Y, Hashimoto E, Minjares C, Kennedy S, Uto H, Yamauchi K, Kobayashi M, Yusa S, Muller U, Hayashi N, Miyazaki T  Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages.  J Biol Chem  2001  276:22910-4 
2973  Shiina T, Morimatsu M, Kitamura H, Ito T, Kidou S, Matsubara K, Matsuda Y, Saito M, Syuto B  Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene.  Immunogenetics  2001  53:649-55 
2664  Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoe, Kazunori, Day, Noorbibi K, Good, Robert A, Ohno, Hideki  Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages.  Proc Natl Acad Sci U S A  2002  99:9392-7  PubMed ID: 12089332
2654  Muroi, Masashi, Tanamoto, Ken-Ichi  The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4.  Infect Immun  2002  70:6043-7  PubMed ID: 12379680
3200  Suzuki, Shogo, Nishimaki-Mogami, Tomoko, Tamehiro, Norimasa, Inoue, Kazuhide, Arakawa, Reijiro, Abe-Dohmae, Sumiko, Tanaka, Arowu R, Ueda, Kazumitsu, Yokoyama, Shinji  Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.  Arterioscler Thromb Vasc Biol  2004  24:519-25  PubMed ID: 14726413
3229  Okuhira, Kei-ichiro, Tsujita, Maki, Yamauchi, Yoshio, Abe-Dohmae, Sumiko, Kato, Koichi, Handa, Tetsurou, Yokoyama, Shinji  Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL.  J Lipid Res  2004  45:645-52  PubMed ID: 14729855
3193  Ban, Hyun Seung, Suzuki, Katsuya, Lim, Soon Sung, Jung, Sang Hoon, Lee, Sanghyun, Ji, Jun, Lee, Hye Seung, Lee, Yeon Sil, Shin, Kuk Hyun, Ohuchi, Kazuo  Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells.  Biochem Pharmacol  2004  67:1549-57  PubMed ID: 15041472
3212  Kato, Sawako, Yuzawa, Yukio, Tsuboi, Naotake, Maruyama, Shoichi, Morita, Yoshiki, Matsuguchi, Tetsuya, Matsuo, Seiichi  Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.  J Am Soc Nephrol  2004  15:1289-99 
2688  Takahashi, Tetsuyuki, Takasuka, Nobuo, Iigo, Masaaki, Baba, Masaki, Nishino, Hoyoku, Tsuda, Hiroyuki, Okuyama, Toru  Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.  Cancer Sci  2004  95:448-53  PubMed ID: 15132774
3220  Adachi, Yoshiyuki, Ishii, Takashi, Ikeda, Yoshihiko, Hoshino, Akiyoshi, Tamura, Hiroshi, Aketagawa, Jun, Tanaka, Shigenori, Ohno, Naohito  Characterization of beta-glucan recognition site on C-type lectin, dectin 1.  Infect Immun  2004  72:4159-71  PubMed ID: 15213161
3364  Hatao, Fumihiko, Muroi, Masashi, Hiki, Naoki, Ogawa, Toshihisa, Mimura, Yoshikazu, Kaminishi, Michio, Tanamoto, Ken-ichi  Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.  J Leukoc Biol  2004  76:904-8  PubMed ID: 15258191
3197  Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa  Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.  J Biol Chem  2004  279:45969-79  PubMed ID: 15304486
2865  Ikeda, Fumiyo, Nishimura, Riko, Matsubara, Takuma, Tanaka, Sakae, Inoue, Jun-ichiro, Reddy, Sakamuri V, Hata, Kenji, Yamashita, Kenji, Hiraga, Toru, Watanabe, Toshiyuki, Kukita, Toshio, Yoshioka, Katsuji, Rao, Anjana, Yoneda, Toshiyuki  Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.  J Clin Invest  2004  114:475-84  PubMed ID: 15314684
2922  Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya  Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.  Blood  2005  105:711-20  PubMed ID: 15345588
3365  Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi  Characterization of inorganic phosphate transport in osteoclast-like cells.  Am J Physiol Cell Physiol  2005  288:C921-31  PubMed ID: 15601753
3392  Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko  Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages.  Genes Cells  2005  10:357-68 
3232  Arakawa, Reijiro, Tamehiro, Norimasa, Nishimaki-Mogami, Tomoko, Ueda, Kazumitsu, Yokoyama, Shinji  Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner.  Arterioscler Thromb Vasc Biol  2005  25:1193-7  PubMed ID: 15790930
3210  Hou, De-Xing, Yanagita, Takashi, Uto, Takuhiro, Masuzaki, Satoko, Fujii, Makoto  Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved.  Biochem Pharmacol  2005  70:417-25  PubMed ID: 15963474
3190  Hassan, Ferdaus, Islam, Shamima, Mu, Mya Mya, Ito, Hiroyasu, Koide, Naoki, Mori, Isamu, Yoshida, Tomoaki, Yokochi, Takashi  Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation.  Mol Cancer Res  2005  3:373-9  PubMed ID: 16046548
3098  Suganami, Takayoshi, Nishida, Junko, Ogawa, Yoshihiro  A Paracrine Loop Between Adipocytes and Macrophages Aggravates Inflammatory Changes. Role of Free Fatty Acids and Tumor Necrosis Factor {alpha}  Arterioscler Thromb Vasc Biol  2005  25:2062-2068 
3209  Uto, Takuhiro, Fujii, Makoto, Hou, De-Xing  6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.  Biochem Pharmacol  2005  70:1211-21  PubMed ID: 16139249
7036  Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y.  Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.  Sci Rep  2017  7:44754  PubMed ID: 28303974
7077  Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.  Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.  Sci Rep  2016  6:23097  PubMed ID: 26975571
7094  Ryohei Hamaguchi, Yukihiro Kuroda  A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs.  Chromatography  2016  37:35-38 
7119  Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T.  Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice.  Peptides  2015  75:101-8  PubMed ID: 26643956
7137  Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K.  Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.  Sci Rep  2015  5:17205  PubMed ID: 26598133
7148  Ohta T, Kusano K, Ido A, Miura C, Miura T.  Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response.  Carbohydr Polym  2015  136:995-1001  PubMed ID: 26572439
7157  Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K.  Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.  Biosci. Biotechnol. Biochem.  2015  80:501-9  PubMed ID: 26540411
7221  Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K.  Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade.  Mol Nutr Food Res  2015  59:2502-10  PubMed ID: 26346532
7230  Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T.  Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans.  Microb. Pathog.  2015  94:2-11  PubMed ID: 26318142
7274  Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638
7293  Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.  Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.  Endocrinology  2015  156:3680-94  PubMed ID: 26132918
7321  Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S.  Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity.  J. Dent. Res.  2015  94:1085-91  PubMed ID: 26040283
7340  Suzuki N, Takimoto K, Kawashima N.  Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions.  J Endod  2015  41:1474-9  PubMed ID: 25990199
7420  Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O.  Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation.  J. Cell. Biochem.  2015  116:2247-57  PubMed ID: 25820496
7448  Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y.  ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.  Biol. Pharm. Bull.  2015  38:482-6  PubMed ID: 25757932
7451  Hashimoto M, Imazato S.  Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages.  Dent Mater  2015  31:556-64  PubMed ID: 25749564
7467  Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H.  Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.  Biosci. Biotechnol. Biochem.  2015  79:799-807  PubMed ID: 25721815
7469  Hashimoto M, Sasaki J, Imazato S.  Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2015  104:241-52  PubMed ID: 25715832
7492  Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.  Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.  Am. J. Physiol. Renal Physiol.  2015  308:F878-87  PubMed ID: 25656369
7505  Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T.  Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages.  Biosci. Biotechnol. Biochem.  2015  79:82-7  PubMed ID: 25603813
7517  Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T.  Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice.  Biopolymers  2015  104:73-83  PubMed ID: 25581614
7526  F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi  Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid).  Polymer Journal  2015  47:631-638 
7581  Hiroi M, Sakaeda Y, Yamaguchi H, Ohmori Y.  Anti-inflammatory cytokine interleukin-4 inhibits inducible nitric oxide synthase gene expression in the mouse macrophage cell line RAW264.7 through the repression of octamer-dependent transcription.  Mediators Inflamm.  2014  2013:369693  PubMed ID: 24459328
7584  T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka  Effects of Atractylodis Lanceae Rhizoma on in?ammatory mediator production from the RAW264 macrophage cell line.  J Traditional Medicines  2013  30:124-131 
7589  Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S.  A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.  J Crohns Colitis  2012  6:215-25  PubMed ID: 22325176
7599  Takano K, Sato K, Negishi Y, Aramaki Y.  Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes.  Arch. Biochem. Biophys.  2011  518:89-94  PubMed ID: 22203089
7608  Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H.  Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction.  Cell. Immunol.  2011  273:73-8  PubMed ID: 22177846
7609  Uto T, Morinaga O, Tanaka H, Shoyama Y.  Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.  Biochem. Biophys. Res. Commun.  2011  417:473-8  PubMed ID: 22178686
7621  Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.  Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.  Inflammation  2011  35:1062-8  PubMed ID: 22134422
7633  Yamamoto H, Abe Y, Miyazato A, Tanno D, Tanaka M, Miyasaka T, Ishii K, Kawakami K.  Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi.  FEMS Immunol. Med. Microbiol.  2011  63:363-72  PubMed ID: 22092563
7639  Uto T, Qin GW, Morinaga O, Shoyama Y.  17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.  Int. Immunopharmacol.  2011  12:101-9  PubMed ID: 22080918
7667  Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H.  Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.  J Physiol Sci  2011  62:59-62  PubMed ID: 21968540
7678  Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H.  Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression.  Innate Immun  2011  18:429-37  PubMed ID: 21948282
7702  Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX.  A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages.  Nutr Cancer  2011  63:1064-73  PubMed ID: 21864060
7725  Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T.  An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages.  Biosci. Biotechnol. Biochem.  2011  75:1582-7  PubMed ID: 21821941
7745  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M.  Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.  Biochem. Biophys. Res. Commun.  2011  411:143-9  PubMed ID: 21723254
7750  Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y.  Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell.  Mol. Immunol.  2011  48:2052-8  PubMed ID: 21764457
7789  Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y.  Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.  Toxicol. Appl. Pharmacol.  2011  255:32-9  PubMed ID: 21651925
7794  Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.  An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.  Cancer Immunol. Immunother.  2011  60:1439-46  PubMed ID: 21644032
7850  Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.  The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.  Bone  2011  49:264-74  PubMed ID: 21504804
7851  Akagi T, Shima F, Akashi M.  Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.  Biomaterials  2011  32:4959-67  PubMed ID: 21482432
7901  Yamazaki Y, Kawano Y.  Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.  Chem. Pharm. Bull.  2011  59:388-91  PubMed ID: 21372424
7921  Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.  Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.  Exp. Cell Res.  2011  317:1134-46  PubMed ID: 21338601
7949  Arisaka M, Takano K, Negishi Y, Arima H, Aramaki Y.  Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes.  Arch. Biochem. Biophys.  2011  508:72-7  PubMed ID: 21315683
7966  Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.  Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans.  Diabetes  2011  60:819-26  PubMed ID: 21282371
8010  Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway.  Microbiol. Immunol.  2011  55:160-7  PubMed ID: 21204955
8050  Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M.  Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms.  J. Agric. Food Chem.  2010  58:12735-43  PubMed ID: 21082860
8052  Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O.  Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion.  Anal. Biochem.  2010  410:7-12  PubMed ID: 21078287
8058  Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, Oshima M.  Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors.  Gastroenterology  2010  140:596-607.e7  PubMed ID: 21070778
8060  Ueda H, Ippoushi K, Takeuchi A.  Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties.  Biosci. Biotechnol. Biochem.  2010  74:2248-52  PubMed ID: 21071834
8066  Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT.  Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo.  Eur. J. Pharmacol.  2010  650:511-8  PubMed ID: 21047508
8067  Kamio N, Akifusa S, Yamashita Y.  Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species.  Free Radic. Res.  2010  45:336-41  PubMed ID: 21034360
8085  Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.  Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.  In Vivo  2010  24:735-43  PubMed ID: 20952742
8102  Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.  Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.  Biol. Pharm. Bull.  2010  33:1733-9  PubMed ID: 20930384
8113  Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.  Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.  Mol. Cancer Ther.  2010  9:2960-9  PubMed ID: 20858724
8135  Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K.  The effective therapy of cyclosporine A with drug delivery system in experimental colitis.  J Drug Target  2010  19:458-67  PubMed ID: 20804404
8136  Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y.  Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.  Toxicol. Lett.  2010  199:123-8  PubMed ID: 20804833
8168  Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T.  Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.  Biol. Pharm. Bull.  2010  33:1355-9  PubMed ID: 20686231
8181  Nakatsuka R, Nozaki T, Shinohara M, Ohura K.  Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.  J. Pharmacol. Sci.  2010  113:271-5  PubMed ID: 20647687
8208  Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.  Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.  Eur. J. Appl. Physiol.  2010  110:797-803  PubMed ID: 20602110
8210  Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53.  Cancer Invest.  2010  28:806-12  PubMed ID: 20594067
8214  Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M.  Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts.  Am. J. Physiol., Cell Physiol.  2010  299:C570-8  PubMed ID: 20592242
8221  Yasuzaki Y, Yamada Y, Harashima H.  Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.  Biochem. Biophys. Res. Commun.  2010  397:181-6  PubMed ID: 20580633
8224  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y.  Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells.  J. Cell. Biochem.  2010  111:597-606  PubMed ID: 20564237
8228  Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T.  Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.  Horm. Metab. Res.  2010  42:632-6  PubMed ID: 20560107
8229  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.  Cell. Immunol.  2010  264:114-8  PubMed ID: 20557878
8249  Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T.  Polaprezinc Protects Mice against Endotoxin Shock.  J Clin Biochem Nutr  2010  46:234-43  PubMed ID: 20490319
8258  Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y.  Expression levels of adiponectin receptors and periodontitis.  J. Periodont. Res.  2010  45:296-300  PubMed ID: 20470261
8273  Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K.  Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.  Cell. Immunol.  2010  263:241-50  PubMed ID: 20451901
8282  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.  Immunol. Lett.  2010  131:166-9  PubMed ID: 20417662
8286  Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.  Immunology  2010  131:59-66  PubMed ID: 20406300
8335  Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y.  Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.  Exp. Anim.  2010  59:47-55  PubMed ID: 20224169
8359  Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.  Inhibitory effect of luteolin on osteoclast differentiation and function.  Cytotechnology  2010  61:125-34  PubMed ID: 20162352
8368  Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.  Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.  J Med Food  2010  13:156-62  PubMed ID: 20136450
8369  Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M.  Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.  Int. Immunol.  2010  22:271-80  PubMed ID: 20133493
8372  Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y.  Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.  FEBS Lett.  2010  584:1016-20  PubMed ID: 20122929
8373  Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.  Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.  J. Immunol.  2010  184:2442-8  PubMed ID: 20118276
8396  Suzuki T, Chang MO, Kitajima M, Takaku H.  Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.  Cell. Immunol.  2010  262:35-43  PubMed ID: 20060108
8415  Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.  Innate Immun  2009  17:97-105  PubMed ID: 20023007
8426  Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T.  Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages.  Mol Nutr Food Res  2009  54:797-804  PubMed ID: 19998383
8455  Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y.  Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).  Innate Immun  2009  17:3-15  PubMed ID: 19897531
8462  Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T.  Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.  J. Bone Miner. Res.  2009  25:1068-76  PubMed ID: 19874196
8465  Sugiyama K, Muroi M, Tanamoto K, Nishijima M, Sugita-Konishi Y.  Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells.  Toxicol. Lett.  2009  192:150-4  PubMed ID: 19857559
8488  Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K.  Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages.  Eur J Nutr  2009  49:119-26  PubMed ID: 19784539
8495  Katsuura S, Imamura T, Bando N, Yamanishi R.  beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages.  Mol Nutr Food Res  2009  53:1396-405  PubMed ID: 19760679
8549  Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K.  Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide.  Biochim. Biophys. Acta  2009  1792:1011-8  PubMed ID: 19559790
8550  Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y.  Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.  FEMS Immunol. Med. Microbiol.  2009  56:241-7  PubMed ID: 19552715
8551  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice.  FEMS Immunol. Med. Microbiol.  2009  56:204-11  PubMed ID: 19538513
8578  Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.  Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.  Infect. Immun.  2009  77:3056-64  PubMed ID: 19433551
8589  Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y.  Extract from Calotropis procera latex activates murine macrophages.  J Nat Med  2009  63:297-303  PubMed ID: 19399577
8637  Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H.  Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.  J. Bone Miner. Res.  2009  24:1194-205  PubMed ID: 19257825
8640  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nishihara T, Yamashita Y.  Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.  Free Radic. Biol. Med.  2009  46:1308-16  PubMed ID: 19250964
8641  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Involvement of Ca(2+) in globular adiponectin-induced reactive oxygen species.  Biochem. Biophys. Res. Commun.  2009  381:649-53  PubMed ID: 19249286
8642  Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T.  Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.  Cell. Immunol.  2009  256:99-103  PubMed ID: 19251253
8648  Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T.  Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells.  Immunopharmacol Immunotoxicol  2009  31:103-7  PubMed ID: 19234958
8654  Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.  Clin. Exp. Immunol.  2009  155:552-8  PubMed ID: 19220841
8663  Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T.  Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.  Innate Immun  2009  15:33-41  PubMed ID: 19201823
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8731  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.  Free Radic. Biol. Med.  2008  45:1326-39  PubMed ID: 18775488
8739  Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S.  Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.  J Nat Med  2008  63:21-7  PubMed ID: 18636311
8740  Nakamura T, Kodama N, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ueno K, Ishikawa T, Yano S.  Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7.  J Nat Med  2008  63:107-10  PubMed ID: 18626726
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8754  Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T.  Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages.  Shock  2008  30:734-9  PubMed ID: 18496239
8815  Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y.  Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion.  Dent Mater J  2007  25:726-32  PubMed ID: 17338307
8850  Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.  Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.  FEMS Immunol. Med. Microbiol.  2006  49:28-34  PubMed ID: 17094790
8917  Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai  Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids  Yonago Acta Med.  2006  49:39-47 
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9122  Kobayashi Y, Mizoguchi T, Take I, Kurihara S, Udagawa N, Takahashi N.  Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1.  J. Biol. Chem.  2005  280:11395-403  PubMed ID: 15647289
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9550  Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y.  N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.  Bone Rep  2016  5:15-21  PubMed ID: 28326343
9554  Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H.  Acid-inducible proton influx currents in the plasma membrane of murine osteoclast-like cells.  Pflugers Arch.  2016  468:837-47  PubMed ID: 26843093
9564  Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.  Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.  J. Biol. Chem.  2016  291:7004-16  PubMed ID: 26865635
9569  Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.  NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.  Phytomedicine  2016  23:417-28  PubMed ID: 27002412
9607  Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K.  NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol.  J Toxicol Sci  2016  41:273-9  PubMed ID: 26961612
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9612  Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.  TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells.  J. Cell. Physiol.  2016  231:2761-7  PubMed ID: 26989816
9690  Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K.  Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells.  Mediators Inflamm.  2016  2016:5701959  PubMed ID: 27313399
9692  Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T.  Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect.  J. Agric. Food Chem.  2016  64:4246-54  PubMed ID: 27170112
9706  Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G.  Effect of macrophages on in vitro corrosion behavior of magnesium alloy.  J Biomed Mater Res A  2016  104:2476-87  PubMed ID: 27223576
9723  Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K.  DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.  J. Cell. Physiol.  2017  232:617-624  PubMed ID: 27312515
9740  Sunarso , Toita R, Tsuru K, Ishikawa K.  A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses.  J Mater Sci Mater Med  2016  27:127  PubMed ID: 27344451
9747  Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.  Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.  Eur. J. Pharmacol.  2016  789:17-26  PubMed ID: 27373848
9818  Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.  A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.  Sci Rep  2016  6:32259  PubMed ID: 27573075
9882  Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.  γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.  Sci Rep  2016  6:35930  PubMed ID: 27775020
9922  Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J.  The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.  Invest. Ophthalmol. Vis. Sci.  2016  57:5945-5953  PubMed ID: 27820950
9944  Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y.  RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.  FASEB J.  2017  31:781-792  PubMed ID: 27836987
9964  Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N.  Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.  Biochem. Biophys. Res. Commun.  2017  482:1122-1128  PubMed ID: 27914813
9969  Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.  Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.  Sci Rep  2016  6:38013  PubMed ID: 27892542
10001  Quan H, Park HC, Kim Y, Yang HC.  Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation.  J Biomed Mater Res A  2017  105:1479-1486  PubMed ID: 27998010
10074  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646
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10122  Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T.  Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase.  J. Pept. Sci.  2017  23:252-260  PubMed ID: 28185358
10165  Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y.  Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation.  Biol. Pharm. Bull.  2017  40:352-356  PubMed ID: 28250278
10169  Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G.  Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method.  Mater Sci Eng C Mater Biol Appl  2017  75:1178-1183  PubMed ID: 28415404
10190  Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M.  Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.  Microbiologyopen  2017  6:  PubMed ID: 28294553
10215  Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K.  CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.  J. Oral Maxillofac. Surg.  2017  75:2144-2153  PubMed ID: 28399391
10230  Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S.  Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.  J Proteomics  2017  161:26-37  PubMed ID: 28373035
10285  Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y.  Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice.  PLoS ONE  2017  12:e0176324  PubMed ID: 28448521
10288  Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.  Effect of physicochemical character differences on the genotoxic potency of kaolin.  Genes Environ  2017  39:12  PubMed ID: 28469735
10335  Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX.  Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators.  J. Agric. Food Chem.  2017  65:5133-5141  PubMed ID: 28573848
10342  Fujihara Y, Hikita A, Takato T, Hoshi K.  Roles of macrophage migration inhibitory factor in cartilage tissue engineering.  J. Cell. Physiol.  2018  233:1490-1499  PubMed ID: 28574571
10380  Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.  Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.  Clin. Exp. Immunol.  2017  190:54-67  PubMed ID: 28640392
10432  Tokuyama-Nakai S, Kimura H, Ishihara T, Jisaka M, Yokota K.  In Vitro Anti-inflammatory and Antioxidant Activities of 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-O-Glycosides and Their Aglycone from Leaves of Polygonum tinctorium Lour.  Appl. Biochem. Biotechnol.  2018  184:414-431  PubMed ID: 28721651
10551  Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K.  The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content.  Food Funct  2017  8:4150-4158  PubMed ID: 29022634
10557  Elfeky M, Yoneshiro T, Okamatsu-Ogura Y, Kimura K.  Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells.  J. Biochem.  2018  163:143-153  PubMed ID: 29048484
10569  Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation.  J. Cell. Mol. Med.  2018  22:1138-1147  PubMed ID: 29063666
10614  Stockler-Pinto MB, Soulage CO, Borges NA, Cardozo LFMF, Dolenga CJ, Nakao LS, Pecoits-Filho R, Fouque D, Mafra D.  From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-κB/Nrf2 expression.  Int Urol Nephrol  2018  50:347-354  PubMed ID: 29151180
10645  Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.  Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.  Biochem. Biophys. Res. Commun.  2018  495:1901-1907  PubMed ID: 29225172
10696  Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y.  Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages.  Biol. Pharm. Bull.  2018  41:132-137  PubMed ID: 29311475
10704  Hanagata N, Li X, Chen MH, Li J, Hattori S.  Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities.  Int J Nanomedicine  2018  13:43-62  PubMed ID: 29317815
10708  Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K.  CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.  Int J Mol Sci  2018  19:  PubMed ID: 29316651
10711  Egami Y, Araki N.  Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis.  Microscopy (Oxf)  2018  67:68-74  PubMed ID: 29340604
10714  Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.  Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.  J Clin Biochem Nutr  2018  62:139-147  PubMed ID: 29610553
10782  Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K.  Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages.  J Oleo Sci  2018  67:471-477  PubMed ID: 29526880
10790  El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M.  Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence.  Phytomedicine  2018  42:126-134  PubMed ID: 29655678
10799  Kawai C, Yamauchi A, Kuribayashi F.  Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.  Microbiol. Immunol.  2018  62:269-280  PubMed ID: 29573449
10852  Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang  In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root  Journal of the Taiwan Institute of Chemical Engineers  2016  61:75-82 
10857    Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients   Journal of Cosmetics, Dermatological Sciences and Applications  2016  6, 9-18 
10869    Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves  Food Science and Technology Research  2016  22 
10915    Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity  Journal of Biomaterials and Tissue Engineering,  2017  7, 139-146 
10949    Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells  International Journal of Chemistry  2017  9 
11027  Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.  Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy  Mol Ther Nucleic Acids  2018  10:159-169  PubMed ID: 29499930
11198  Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.  Coupling of bone resorption and formation by RANKL reverse signalling.  Nature  2018    PubMed ID: 30185903
4050  Mukai Y, Yamanishi R.  Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line.  Food Sci Nutr  2018    PubMed ID: 30258608
11098  Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T.  The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.  Sci Rep  2018    PubMed ID: 29892000
11116  Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y.  Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein.  Anticancer Res.  2018    PubMed ID: 29970565
11122  Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T.  Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel.  Biomacromolecules  2018    PubMed ID: 29985587
11167  Chaweewannakorn W, Ariyoshi W, Okinaga T, Fujita Y, Maki K, Nishihara T.  Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1).  J. Cell. Physiol.  2018    PubMed ID: 30105896
11173  Madhyastha R, Madhyastha H, Pengjam Y, Nurrahmah QI, Nakajima Y, Maruyama M.  The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin.  J Nat Med  2018    PubMed ID: 30116953
11186  Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y.  Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.  Biosci. Biotechnol. Biochem.  2018    PubMed ID: 30146952
11200  Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.  Sendai virus C protein limits NO production in infected RAW264.7 macrophages.  Innate Immun  2018    PubMed ID: 30189760
11074  Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.  Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.  J. Biol. Chem.  2018    PubMed ID: 29760187
11112  Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  Biochem. Pharmacol.  2018    PubMed ID: 29940171
11249  Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S.  2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.  Food Chem. Toxicol.  2018    PubMed ID: 30316843
11279  Sun S, Li K, Xiao L, Lei Z, Zhang Z.  Characterization of polysaccharide from Helicteres angustifolia L. and its immunomodulatory activities on macrophages RAW264.7.  Biomed. Pharmacother.  2019    PubMed ID: 30396084
11335  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Ando K, Tanimoto K.  The effect of mesenchymal stem cells on osteoclast precursor cell differentiation.  J Oral Sci  2019    PubMed ID: 30541990
11493  Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice.  Polymers (Basel)  2018    PubMed ID: 30961309
11349  Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura SI.  5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages.  BMC Immunol.  2018    PubMed ID: 30567499
11361  Islam Z, Inui T, Ishibashi O.  Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30595385
11380  Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H.  Liposomes with temperature-responsive reversible surface properties.  Colloids Surf B Biointerfaces  2019    PubMed ID: 30641302
11396  Yoshinaga N, Uchida S, Naito M, Osada K, Cabral H, Kataoka K.  Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.  Biomaterials  2019    PubMed ID: 30669016
11383  Manabe Y, Hirata T, Sugawara T.  Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors.  J Oleo Sci  2019    PubMed ID: 30651415
11389  Wang W, Nakashima KI, Hirai T, Inoue M.  Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers.  J Nat Med  2019    PubMed ID: 30656541
11457  Takahashi S, Yoshida M, Watanabe MM, Isoda H.  Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells.  Biomed Res Int  2019    PubMed ID: 30809537
11437  Yanagihara Y, Inoue K, Saeki N, Sawada Y, Yoshida S, Lee J, Iimura T, Imai Y.  Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin.  Bone  2019    PubMed ID: 30771488
11454  Antwi CA, Amisigo CM, Adjimani JP, Gwira TM.  In vitro activity and mode of action of phenolic compounds on Leishmania donovani.  PLoS Negl Trop Dis  2019    PubMed ID: 30802252
11477  Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T.  Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.  Cell Chem Biol  2019    PubMed ID: 30853417
4441  Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi  Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels  Trends in Immunotherapy  2018  2 
4324  Quan H, Kim Y, Park HC, Yang HC.  Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages.  J Biomed Mater Res A  2018    PubMed ID: 29781181
4325  Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K.  Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.  Int J Nanomedicine  2018    PubMed ID: 30122920
4326  Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K.  Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30301531
4327  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K.  Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull.  J Dent Sci  2018    PubMed ID: 30895145
4328  Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K.  The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells.  J Oral Sci  2018    PubMed ID: 29925706
4329  Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T.  Mechanisms involved in enhancement of osteoclast formation by activin-A.  J. Cell. Biochem.  2018    PubMed ID: 29737562
4330  Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.  Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.  Int. Immunopharmacol.  2018    PubMed ID: 30005227
4331  El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S.  New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella.  Fitoterapia  2018    PubMed ID: 29729401
4332  Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K.  Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.  Oxid Med Cell Longev  2018    PubMed ID: 30533177
4333  Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H.  Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis.  Biosci. Biotechnol. Biochem.  2018    PubMed ID: 29165050
4334  Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y.  Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.  Cancer Sci.  2018    PubMed ID: 29444368
4335  Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N.  Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase.  Biochim Biophys Acta Mol Cell Biol Lipids  2018    PubMed ID: 29447909
4336  Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H.  Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells.  Front Physiol  2018    PubMed ID: 30319432
4496  Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ.  Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.  Bone  2018  116:232-247  PubMed ID: 30125729
4497  Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka T, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.  Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells.  Int J Nanomedicine  2018  13:6079-6088  PubMed ID: 30323595
4498  Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H.  Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide.  Biochem. Cell Biol.  2018  96(6):769-776  PubMed ID: 29958095
4499  Choodej S, Pudhom K, Mitsunaga T.  Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.  Planta Med.  2018  84(5):329-335  PubMed ID: 28962049
4526  Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata  Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells  Mutation Research/Genetic Toxicology and Environmental Mutagenesis  2017  818, 7-16  PubMed ID: 28477879



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