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RCB0535 : RAW 264  update : 2019/12/11
CommentMouse leukemic monocyte. Abelson leukemia virus induced. Since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECA85062803 prior to order. Application consideration(PDF 580KB)
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use. However, since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECA85062803 prior to order.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor ECACC
Year of deposit 1990
Animal mouse < Mammals
Strain name BALB/c
Tissue leukemic monocyte
Classification transformed
History overseas, ECACC
Lifespan infinite
Morphology other
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 10% FBS + 0.1mM NEAA
Antibiotics Free
Passage method 0.25% trypsin + 0.02% EDTA
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP (mouse) OK
Images
deposit info
lot info
Reference information Reference 1
User's Publication 288


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Reference
716  Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS.  Ralph P, Nakoinz I  J Immunol  1977  119:950-54  PubMed ID: 894031

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User's Publication
3160  Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.  Wei, Ping, Taniguchi, Susumu, Sakai, Yoshiyuki, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Oda, Shinya, Nakabeppu, Yusaku, Nishimura, Junji, Ikuyama, Shoichiro  J Biochem  2005  138:399-412  PubMed ID: 16272134
2890  Transcriptional regulation of the MAIL gene in LPS-stimulated RAW264 mouse macrophages.  Ito T, Morimatsu M, Oonuma T, Shiina T, Kitamura H, Syuto B  Gene  2004  342:137-43  PubMed ID: 15527973
2903  Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation.  Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K  Biochem Biophys Res Commun  2005  332:793-9  PubMed ID: 15907790
2904  Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.  Itoh CE, Kizaki T, Hitomi Y, Hanawa T, Kamiya S, Ookawara T, Suzuki K, Izawa T, Saitoh D, Haga S, Ohno H  Biochem Biophys Res Commun  2004  322:979-84  PubMed ID: 15336560
1645  Modification of Immunopharmacologicaln Activities of Synthetic Monosaccharide Lipid A Analogue, GLA60, by Lysozyme  Tanida N, Ohno N, Adachi Y, Matsuura M, Nakano M, Kiso M, Hasegawa A, Yadomae T  J Biochem  1992  112:616-623  PubMed ID: 1478920
2366  Induction of nitric oxide synthase by lipopolysaccharide and its inhibition by auranofin in RAW 264.7 cells.  Yamashita M, Niki H, Yamada M, Mue S, Ohuchi K  Eur J Pharmacol  1997  338:151-8  PubMed ID: 9455997
2423  A physiologic role of Bcl-xL induced in activated macrophages.  Okada S, Zhang H, Hatano M, Tokuhisa T  J Immunol  1998  160:2590-6  PubMed ID: 9510156
3224  Characterization of apolipoprotein-mediated HDL generation induced by cAMP in a murine macrophage cell line.  Abe-Dohmae S, Suzuki S, Wada Y, Aburatani H, Vance, D E, Yokoyama S  Biochemistry  2000  39:11092-9  PubMed ID: 10998247
3225  Enhancement of the cAMP-induced apolipoprotein-mediated cellular lipid release by calmodulin inhibitors W7 and W5 from RAW 264 mouse macrophage cell line cells.  Suzuki S, Abe-Dohmae S, Fukutomi T, Ito S, Itoh M, Yokoyama S  J Cardiovasc Pharmacol  2000  36:609-16  PubMed ID: 11065221
2504  Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages.  Haruta I, Kato Y, Hashimoto E, Minjares C, Kennedy S, Uto H, Yamauchi K, Kobayashi M, Yusa S, Muller U, Hayashi N, Miyazaki T  J Biol Chem  2001  276:22910-4  PubMed ID: 11294859
2973  Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene.  Shiina T, Morimatsu M, Kitamura H, Ito T, Kidou S, Matsubara K, Matsuda Y, Saito M, Syuto B  Immunogenetics  2001  53:649-55  PubMed ID: 11797098
2664  Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages.  Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoe, Kazunori, Day, Noorbibi K, Good, Robert A, Ohno, Hideki  Proc Natl Acad Sci U S A  2002  99:9392-7  PubMed ID: 12089332
2654  The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4.  Muroi, Masashi, Tanamoto, Ken-Ichi  Infect Immun  2002  70:6043-7  PubMed ID: 12379680
3200  Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.  Suzuki, Shogo, Nishimaki-Mogami, Tomoko, Tamehiro, Norimasa, Inoue, Kazuhide, Arakawa, Reijiro, Abe-Dohmae, Sumiko, Tanaka, Arowu R, Ueda, Kazumitsu, Yokoyama, Shinji  Arterioscler Thromb Vasc Biol  2004  24:519-25  PubMed ID: 14726413
3229  Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL.  Okuhira, Kei-ichiro, Tsujita, Maki, Yamauchi, Yoshio, Abe-Dohmae, Sumiko, Kato, Koichi, Handa, Tetsurou, Yokoyama, Shinji  J Lipid Res  2004  45:645-52  PubMed ID: 14729855
3193  Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells.  Ban, Hyun Seung, Suzuki, Katsuya, Lim, Soon Sung, Jung, Sang Hoon, Lee, Sanghyun, Ji, Jun, Lee, Hye Seung, Lee, Yeon Sil, Shin, Kuk Hyun, Ohuchi, Kazuo  Biochem Pharmacol  2004  67:1549-57  PubMed ID: 15041472
3212  Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.  Kato, Sawako, Yuzawa, Yukio, Tsuboi, Naotake, Maruyama, Shoichi, Morita, Yoshiki, Matsuguchi, Tetsuya, Matsuo, Seiichi  J Am Soc Nephrol  2004  15:1289-99  PubMed ID: 15100369
2688  Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.  Takahashi, Tetsuyuki, Takasuka, Nobuo, Iigo, Masaaki, Baba, Masaki, Nishino, Hoyoku, Tsuda, Hiroyuki, Okuyama, Toru  Cancer Sci  2004  95:448-53  PubMed ID: 15132774
3220  Characterization of beta-glucan recognition site on C-type lectin, dectin 1.  Adachi, Yoshiyuki, Ishii, Takashi, Ikeda, Yoshihiko, Hoshino, Akiyoshi, Tamura, Hiroshi, Aketagawa, Jun, Tanaka, Shigenori, Ohno, Naohito  Infect Immun  2004  72:4159-71  PubMed ID: 15213161
3364  Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.  Hatao, Fumihiko, Muroi, Masashi, Hiki, Naoki, Ogawa, Toshihisa, Mimura, Yoshikazu, Kaminishi, Michio, Tanamoto, Ken-ichi  J Leukoc Biol  2004  76:904-8  PubMed ID: 15258191
3197  Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.  Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa  J Biol Chem  2004  279:45969-79  PubMed ID: 15304486
2865  Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.  Ikeda, Fumiyo, Nishimura, Riko, Matsubara, Takuma, Tanaka, Sakae, Inoue, Jun-ichiro, Reddy, Sakamuri V, Hata, Kenji, Yamashita, Kenji, Hiraga, Toru, Watanabe, Toshiyuki, Kukita, Toshio, Yoshioka, Katsuji, Rao, Anjana, Yoneda, Toshiyuki  J Clin Invest  2004  114:475-84  PubMed ID: 15314684
2922  Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.  Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya  Blood  2005  105:711-20  PubMed ID: 15345588
3365  Characterization of inorganic phosphate transport in osteoclast-like cells.  Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi  Am J Physiol Cell Physiol  2005  288:C921-31  PubMed ID: 15601753
3392  Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages.  Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko  Genes Cells  2005  10:357-68  PubMed ID: 15773898
3232  Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner.  Arakawa, Reijiro, Tamehiro, Norimasa, Nishimaki-Mogami, Tomoko, Ueda, Kazumitsu, Yokoyama, Shinji  Arterioscler Thromb Vasc Biol  2005  25:1193-7  PubMed ID: 15790930
3210  Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved.  Hou, De-Xing, Yanagita, Takashi, Uto, Takuhiro, Masuzaki, Satoko, Fujii, Makoto  Biochem Pharmacol  2005  70:417-25  PubMed ID: 15963474
3190  Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation.  Hassan, Ferdaus, Islam, Shamima, Mu, Mya Mya, Ito, Hiroyasu, Koide, Naoki, Mori, Isamu, Yoshida, Tomoaki, Yokochi, Takashi  Mol Cancer Res  2005  3:373-9  PubMed ID: 16046548
3098  A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha.  Suganami, Takayoshi, Nishida, Junko, Ogawa, Yoshihiro  Arterioscler Thromb Vasc Biol  2005  25:2062-2068  PubMed ID: 16123319
3209  6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.  Uto, Takuhiro, Fujii, Makoto, Hou, De-Xing  Biochem Pharmacol  2005  70:1211-21  PubMed ID: 16139249
7036  Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.  Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y.  Sci Rep  2017  7:44754  PubMed ID: 28303974
7077  Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.  Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.  Sci Rep  2016  6:23097  PubMed ID: 26975571
7094  A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs.  Ryohei Hamaguchi, Yukihiro Kuroda  Chromatography  2016  37:35-38 
7119  Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice.  Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T.  Peptides  2015  75:101-8  PubMed ID: 26643956
7137  Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.  Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K.  Sci Rep  2015  5:17205  PubMed ID: 26598133
7148  Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response.  Ohta T, Kusano K, Ido A, Miura C, Miura T.  Carbohydr Polym  2015  136:995-1001  PubMed ID: 26572439
7157  Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.  Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K.  Biosci. Biotechnol. Biochem.  2015  80:501-9  PubMed ID: 26540411
7221  Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade.  Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K.  Mol Nutr Food Res  2015  59:2502-10  PubMed ID: 26346532
7230  Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans.  Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T.  Microb. Pathog.  2015  94:2-11  PubMed ID: 26318142
7274  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638
7293  Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.  Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.  Endocrinology  2015  156:3680-94  PubMed ID: 26132918
7321  Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity.  Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S.  J. Dent. Res.  2015  94:1085-91  PubMed ID: 26040283
7340  Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions.  Suzuki N, Takimoto K, Kawashima N.  J Endod  2015  41:1474-9  PubMed ID: 25990199
7420  Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation.  Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O.  J. Cell. Biochem.  2015  116:2247-57  PubMed ID: 25820496
7448  ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.  Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y.  Biol. Pharm. Bull.  2015  38:482-6  PubMed ID: 25757932
7451  Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages.  Hashimoto M, Imazato S.  Dent Mater  2015  31:556-64  PubMed ID: 25749564
7467  Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.  Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H.  Biosci. Biotechnol. Biochem.  2015  79:799-807  PubMed ID: 25721815
7469  Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages.  Hashimoto M, Sasaki J, Imazato S.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2015  104:241-52  PubMed ID: 25715832
7492  Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.  Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.  Am. J. Physiol. Renal Physiol.  2015  308:F878-87  PubMed ID: 25656369
7505  Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages.  Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T.  Biosci. Biotechnol. Biochem.  2015  79:82-7  PubMed ID: 25603813
7517  Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice.  Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T.  Biopolymers  2015  104:73-83  PubMed ID: 25581614
7526  Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid).  F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi  Polymer Journal  2015  47:631-638 
7584  Effects of Atractylodis Lanceae Rhizoma on in?ammatory mediator production from the RAW264 macrophage cell line.  T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka  J Traditional Medicines  2013  30:124-131 
7589  A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.  Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S.  J Crohns Colitis  2012  6:215-25  PubMed ID: 22325176
7599  Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes.  Takano K, Sato K, Negishi Y, Aramaki Y.  Arch. Biochem. Biophys.  2011  518:89-94  PubMed ID: 22203089
7608  Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction.  Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H.  Cell. Immunol.  2011  273:73-8  PubMed ID: 22177846
7609  Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.  Uto T, Morinaga O, Tanaka H, Shoyama Y.  Biochem. Biophys. Res. Commun.  2011  417:473-8  PubMed ID: 22178686
7621  Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.  Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.  Inflammation  2011  35:1062-8  PubMed ID: 22134422
7633  Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi.  Yamamoto H, Abe Y, Miyazato A, Tanno D, Tanaka M, Miyasaka T, Ishii K, Kawakami K.  FEMS Immunol. Med. Microbiol.  2011  63:363-72  PubMed ID: 22092563
7639  17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.  Uto T, Qin GW, Morinaga O, Shoyama Y.  Int. Immunopharmacol.  2011  12:101-9  PubMed ID: 22080918
7667  Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.  Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H.  J Physiol Sci  2011  62:59-62  PubMed ID: 21968540
7678  Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression.  Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H.  Innate Immun  2011  18:429-37  PubMed ID: 21948282
7702  A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages.  Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX.  Nutr Cancer  2011  63:1064-73  PubMed ID: 21864060
7725  An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages.  Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T.  Biosci. Biotechnol. Biochem.  2011  75:1582-7  PubMed ID: 21821941
7745  Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M.  Biochem. Biophys. Res. Commun.  2011  411:143-9  PubMed ID: 21723254
7750  Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell.  Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y.  Mol. Immunol.  2011  48:2052-8  PubMed ID: 21764457
7789  Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.  Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y.  Toxicol. Appl. Pharmacol.  2011  255:32-9  PubMed ID: 21651925
7794  An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.  Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.  Cancer Immunol. Immunother.  2011  60:1439-46  PubMed ID: 21644032
7850  The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.  Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.  Bone  2011  49:264-74  PubMed ID: 21504804
7851  Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.  Akagi T, Shima F, Akashi M.  Biomaterials  2011  32:4959-67  PubMed ID: 21482432
7901  Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.  Yamazaki Y, Kawano Y.  Chem. Pharm. Bull.  2011  59:388-91  PubMed ID: 21372424
7921  Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.  Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.  Exp. Cell Res.  2011  317:1134-46  PubMed ID: 21338601
7949  Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes.  Arisaka M, Takano K, Negishi Y, Arima H, Aramaki Y.  Arch. Biochem. Biophys.  2011  508:72-7  PubMed ID: 21315683
7966  Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans.  Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.  Diabetes  2011  60:819-26  PubMed ID: 21282371
8010  Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway.  Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Microbiol. Immunol.  2011  55:160-7  PubMed ID: 21204955
8050  Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms.  Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M.  J. Agric. Food Chem.  2010  58:12735-43  PubMed ID: 21082860
8052  Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion.  Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O.  Anal. Biochem.  2010  410:7-12  PubMed ID: 21078287
8058  Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors.  Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, Oshima M.  Gastroenterology  2010  140:596-607.e7  PubMed ID: 21070778
8060  Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties.  Ueda H, Ippoushi K, Takeuchi A.  Biosci. Biotechnol. Biochem.  2010  74:2248-52  PubMed ID: 21071834
8066  Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo.  Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT.  Eur. J. Pharmacol.  2010  650:511-8  PubMed ID: 21047508
8067  Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species.  Kamio N, Akifusa S, Yamashita Y.  Free Radic. Res.  2010  45:336-41  PubMed ID: 21034360
8085  Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.  Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.  In Vivo  2010  24:735-43  PubMed ID: 20952742
8102  Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.  Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.  Biol. Pharm. Bull.  2010  33:1733-9  PubMed ID: 20930384
8113  Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.  Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.  Mol. Cancer Ther.  2010  9:2960-9  PubMed ID: 20858724
8135  The effective therapy of cyclosporine A with drug delivery system in experimental colitis.  Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K.  J Drug Target  2010  19:458-67  PubMed ID: 20804404
8136  Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.  Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y.  Toxicol. Lett.  2010  199:123-8  PubMed ID: 20804833
8168  Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.  Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T.  Biol. Pharm. Bull.  2010  33:1355-9  PubMed ID: 20686231
8181  Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.  Nakatsuka R, Nozaki T, Shinohara M, Ohura K.  J. Pharmacol. Sci.  2010  113:271-5  PubMed ID: 20647687
8208  Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.  Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.  Eur. J. Appl. Physiol.  2010  110:797-803  PubMed ID: 20602110
8210  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53.  Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Cancer Invest.  2010  28:806-12  PubMed ID: 20594067
8214  Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts.  Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M.  Am. J. Physiol., Cell Physiol.  2010  299:C570-8  PubMed ID: 20592242
8221  Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.  Yasuzaki Y, Yamada Y, Harashima H.  Biochem. Biophys. Res. Commun.  2010  397:181-6  PubMed ID: 20580633
8224  Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells.  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y.  J. Cell. Biochem.  2010  111:597-606  PubMed ID: 20564237
8228  Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.  Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T.  Horm. Metab. Res.  2010  42:632-6  PubMed ID: 20560107
8229  Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Cell. Immunol.  2010  264:114-8  PubMed ID: 20557878
8249  Polaprezinc Protects Mice against Endotoxin Shock.  Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T.  J Clin Biochem Nutr  2010  46:234-43  PubMed ID: 20490319
8258  Expression levels of adiponectin receptors and periodontitis.  Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y.  J. Periodont. Res.  2010  45:296-300  PubMed ID: 20470261
8273  Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.  Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K.  Cell. Immunol.  2010  263:241-50  PubMed ID: 20451901
8282  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Immunol. Lett.  2010  131:166-9  PubMed ID: 20417662
8286  Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.  Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Immunology  2010  131:59-66  PubMed ID: 20406300
8335  Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.  Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y.  Exp. Anim.  2010  59:47-55  PubMed ID: 20224169
8359  Inhibitory effect of luteolin on osteoclast differentiation and function.  Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.  Cytotechnology  2010  61:125-34  PubMed ID: 20162352
8368  Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.  Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.  J Med Food  2010  13:156-62  PubMed ID: 20136450
8369  Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.  Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M.  Int. Immunol.  2010  22:271-80  PubMed ID: 20133493
8372  Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.  Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y.  FEBS Lett.  2010  584:1016-20  PubMed ID: 20122929
8373  Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.  Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.  J. Immunol.  2010  184:2442-8  PubMed ID: 20118276
8396  Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.  Suzuki T, Chang MO, Kitajima M, Takaku H.  Cell. Immunol.  2010  262:35-43  PubMed ID: 20060108
8415  ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.  Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Innate Immun  2009  17:97-105  PubMed ID: 20023007
8426  Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages.  Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T.  Mol Nutr Food Res  2009  54:797-804  PubMed ID: 19998383
8455  Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).  Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y.  Innate Immun  2009  17:3-15  PubMed ID: 19897531
8462  Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.  Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T.  J. Bone Miner. Res.  2009  25:1068-76  PubMed ID: 19874196
8465  Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells.  Sugiyama K, Muroi M, Tanamoto K, Nishijima M, Sugita-Konishi Y.  Toxicol. Lett.  2009  192:150-4  PubMed ID: 19857559
8488  Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages.  Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K.  Eur J Nutr  2009  49:119-26  PubMed ID: 19784539
8495  beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages.  Katsuura S, Imamura T, Bando N, Yamanishi R.  Mol Nutr Food Res  2009  53:1396-405  PubMed ID: 19760679
8549  Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide.  Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K.  Biochim. Biophys. Acta  2009  1792:1011-8  PubMed ID: 19559790
8550  Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.  Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y.  FEMS Immunol. Med. Microbiol.  2009  56:241-7  PubMed ID: 19552715
8551  Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice.  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  FEMS Immunol. Med. Microbiol.  2009  56:204-11  PubMed ID: 19538513
8578  Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.  Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.  Infect. Immun.  2009  77:3056-64  PubMed ID: 19433551
8589  Extract from Calotropis procera latex activates murine macrophages.  Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y.  J Nat Med  2009  63:297-303  PubMed ID: 19399577
8637  Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.  Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H.  J. Bone Miner. Res.  2009  24:1194-205  PubMed ID: 19257825
8640  Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nishihara T, Yamashita Y.  Free Radic. Biol. Med.  2009  46:1308-16  PubMed ID: 19250964
8641  Involvement of Ca(2+) in globular adiponectin-induced reactive oxygen species.  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Biochem. Biophys. Res. Commun.  2009  381:649-53  PubMed ID: 19249286
8642  Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.  Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T.  Cell. Immunol.  2009  256:99-103  PubMed ID: 19251253
8648  Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells.  Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T.  Immunopharmacol Immunotoxicol  2009  31:103-7  PubMed ID: 19234958
8654  Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.  Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Clin. Exp. Immunol.  2009  155:552-8  PubMed ID: 19220841
8663  Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.  Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T.  Innate Immun  2009  15:33-41  PubMed ID: 19201823
8691  Toll-like receptor 4-dependent activation of myeloid dendritic cells by leukocidin of Staphylococcus aureus.  Inden K, Kaneko J, Miyazato A, Yamamoto N, Mouri S, Shibuya Y, Nakamura K, Aoyagi T, Hatta M, Kunishima H, Hirakata Y, Itoh Y, Kaku M, Kawakami K.  Microbes Infect.  2008  11:245-53  PubMed ID: 19111627
8731  Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Free Radic. Biol. Med.  2008  45:1326-39  PubMed ID: 18775488
8739  Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.  Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S.  J Nat Med  2008  63:21-7  PubMed ID: 18636311
8740  Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7.  Nakamura T, Kodama N, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ueno K, Ishikawa T, Yano S.  J Nat Med  2008  63:107-10  PubMed ID: 18626726
8742  The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells.  Nakamura T, Kodama N, Oda M, Tsuchiya S, Arai Y, Kumamoto T, Ishikawa T, Ueno K, Yano S.  J Nat Med  2008  63:15-20  PubMed ID: 18607531
8754  Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages.  Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T.  Shock  2008  30:734-9  PubMed ID: 18496239
8815  Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion.  Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y.  Dent Mater J  2007  25:726-32  PubMed ID: 17338307
8850  Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.  Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.  FEMS Immunol. Med. Microbiol.  2006  49:28-34  PubMed ID: 17094790
8917  Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids  Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai  Yonago Acta Med.  2006  49:39-47 
8972  Neural connections between embryonic stem cell-derived neurons and vestibular hair cells in vitro.  Kim TS, Nakagawa T, Kita T, Higashi T, Takebayashi S, Matsumoto M, Kojima K, Sakamoto T, Ito J.  Brain Res.  2005  1057:127-33  PubMed ID: 16122715
9122  Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1.  Kobayashi Y, Mizoguchi T, Take I, Kurihara S, Udagawa N, Takahashi N.  J. Biol. Chem.  2005  280:11395-403  PubMed ID: 15647289
3135  Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery.  Kimura T. et al.  Materials Science and Engineering C  2004  24:797-801 
9520  Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages.  Lu Y, Cao L, Egami Y, Kawai K, Araki N.  Microscopy (Oxf)  2016  65:233-42  PubMed ID: 26754560
9550  N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.  Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y.  Bone Rep  2016  5:15-21  PubMed ID: 28326343
9554  Acid-inducible proton influx currents in the plasma membrane of murine osteoclast-like cells.  Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H.  Pflugers Arch.  2016  468:837-47  PubMed ID: 26843093
9564  Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.  Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.  J. Biol. Chem.  2016  291:7004-16  PubMed ID: 26865635
9569  NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.  Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.  Phytomedicine  2016  23:417-28  PubMed ID: 27002412
9607  NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol.  Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K.  J Toxicol Sci  2016  41:273-9  PubMed ID: 26961612
9609  Differentiation signalobody: Demonstration of antigen-dependent osteoclast differentiation from a progenitor cell line.  Nakabayashi H, Aoyama S, Kawahara M, Nagamune T.  J. Biosci. Bioeng.  2016  122:357-63  PubMed ID: 26979343
9612  TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells.  Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.  J. Cell. Physiol.  2016  231:2761-7  PubMed ID: 26989816
9690  Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells.  Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K.  Mediators Inflamm.  2016  2016:5701959  PubMed ID: 27313399
9692  Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect.  Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T.  J. Agric. Food Chem.  2016  64:4246-54  PubMed ID: 27170112
9706  Effect of macrophages on in vitro corrosion behavior of magnesium alloy.  Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G.  J Biomed Mater Res A  2016  104:2476-87  PubMed ID: 27223576
9723  DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.  Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K.  J. Cell. Physiol.  2017  232:617-624  PubMed ID: 27312515
9740  A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses.  Sunarso , Toita R, Tsuru K, Ishikawa K.  J Mater Sci Mater Med  2016  27:127  PubMed ID: 27344451
9747  Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.  Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.  Eur. J. Pharmacol.  2016  789:17-26  PubMed ID: 27373848
9818  A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.  Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.  Sci Rep  2016  6:32259  PubMed ID: 27573075
9882  γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.  Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.  Sci Rep  2016  6:35930  PubMed ID: 27775020
9922  The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.  Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J.  Invest. Ophthalmol. Vis. Sci.  2016  57:5945-5953  PubMed ID: 27820950
9944  RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.  Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y.  FASEB J.  2017  31:781-792  PubMed ID: 27836987
9964  Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.  Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N.  Biochem. Biophys. Res. Commun.  2017  482:1122-1128  PubMed ID: 27914813
9969  Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.  Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.  Sci Rep  2016  6:38013  PubMed ID: 27892542
10001  Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation.  Quan H, Park HC, Kim Y, Yang HC.  J Biomed Mater Res A  2017  105:1479-1486  PubMed ID: 27998010
10074  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646
10085  Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33.  Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T.  J. Cell. Physiol.  2017  232:3481-3495  PubMed ID: 28105703
10122  Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase.  Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T.  J. Pept. Sci.  2017  23:252-260  PubMed ID: 28185358
10165  Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation.  Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y.  Biol. Pharm. Bull.  2017  40:352-356  PubMed ID: 28250278
10169  Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method.  Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G.  Mater Sci Eng C Mater Biol Appl  2017  75:1178-1183  PubMed ID: 28415404
10190  Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.  Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M.  Microbiologyopen  2017  6:  PubMed ID: 28294553
10215  CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.  Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K.  J. Oral Maxillofac. Surg.  2017  75:2144-2153  PubMed ID: 28399391
10230  Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.  Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S.  J Proteomics  2017  161:26-37  PubMed ID: 28373035
10285  Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice.  Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y.  PLoS ONE  2017  12:e0176324  PubMed ID: 28448521
10288  Effect of physicochemical character differences on the genotoxic potency of kaolin.  Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.  Genes Environ  2017  39:12  PubMed ID: 28469735
10335  Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators.  Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX.  J. Agric. Food Chem.  2017  65:5133-5141  PubMed ID: 28573848
10342  Roles of macrophage migration inhibitory factor in cartilage tissue engineering.  Fujihara Y, Hikita A, Takato T, Hoshi K.  J. Cell. Physiol.  2018  233:1490-1499  PubMed ID: 28574571
10380  Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.  Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.  Clin. Exp. Immunol.  2017  190:54-67  PubMed ID: 28640392
10432  In Vitro Anti-inflammatory and Antioxidant Activities of 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-O-Glycosides and Their Aglycone from Leaves of Polygonum tinctorium Lour.  Tokuyama-Nakai S, Kimura H, Ishihara T, Jisaka M, Yokota K.  Appl. Biochem. Biotechnol.  2018  184:414-431  PubMed ID: 28721651
10551  The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content.  Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K.  Food Funct  2017  8:4150-4158  PubMed ID: 29022634
10557  Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells.  Elfeky M, Yoneshiro T, Okamatsu-Ogura Y, Kimura K.  J. Biochem.  2018  163:143-153  PubMed ID: 29048484
10569  Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation.  Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  J. Cell. Mol. Med.  2018  22:1138-1147  PubMed ID: 29063666
10614  From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-κB/Nrf2 expression.  Stockler-Pinto MB, Soulage CO, Borges NA, Cardozo LFMF, Dolenga CJ, Nakao LS, Pecoits-Filho R, Fouque D, Mafra D.  Int Urol Nephrol  2018  50:347-354  PubMed ID: 29151180
10645  Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.  Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.  Biochem. Biophys. Res. Commun.  2018  495:1901-1907  PubMed ID: 29225172
10696  Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages.  Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y.  Biol. Pharm. Bull.  2018  41:132-137  PubMed ID: 29311475
10704  Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities.  Hanagata N, Li X, Chen MH, Li J, Hattori S.  Int J Nanomedicine  2018  13:43-62  PubMed ID: 29317815
10708  CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.  Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K.  Int J Mol Sci  2018  19:  PubMed ID: 29316651
10711  Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis.  Egami Y, Araki N.  Microscopy (Oxf)  2018  67:68-74  PubMed ID: 29340604
10714  Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.  Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.  J Clin Biochem Nutr  2018  62:139-147  PubMed ID: 29610553
10782  Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages.  Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K.  J Oleo Sci  2018  67:471-477  PubMed ID: 29526880
10790  Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence.  El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M.  Phytomedicine  2018  42:126-134  PubMed ID: 29655678
10799  Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.  Kawai C, Yamauchi A, Kuribayashi F.  Microbiol. Immunol.  2018  62:269-280  PubMed ID: 29573449
10852  In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root  Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang  Journal of the Taiwan Institute of Chemical Engineers  2016  61:75-82 
10857  Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients     Journal of Cosmetics, Dermatological Sciences and Applications  2016  6, 9-18 
10869  Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves    Food Science and Technology Research  2016  22 
10915  Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity    Journal of Biomaterials and Tissue Engineering,  2017  7, 139-146 
10949  Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells    International Journal of Chemistry  2017  9 
11027  Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy  Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.  Mol Ther Nucleic Acids  2018  10:159-169  PubMed ID: 29499930
11198  Coupling of bone resorption and formation by RANKL reverse signalling.  Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.  Nature  2018  561(7722):195-200  PubMed ID: 30185903
4050  Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line.  Mukai Y, Yamanishi R.  Food Sci Nutr  2018    PubMed ID: 30258608
11098  The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.  Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T.  Sci Rep  2018  8(1):8836  PubMed ID: 29892000
11116  Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein.  Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y.  Anticancer Res.  2018  38(7):4299-4304  PubMed ID: 29970565
11122  Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel.  Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T.  Biomacromolecules  2018  19(8):3280-3290  PubMed ID: 29985587
11167  Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1).  Chaweewannakorn W, Ariyoshi W, Okinaga T, Fujita Y, Maki K, Nishihara T.  J. Cell. Physiol.  2019  234(2):1745-175  PubMed ID: 30105896
11173  The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin.  Madhyastha R, Madhyastha H, Pengjam Y, Nurrahmah QI, Nakajima Y, Maruyama M.  J Nat Med  2019  73(1):59-66  PubMed ID: 30116953
11186  Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.  Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y.  Biosci. Biotechnol. Biochem.  2018  82(12):2109-2117  PubMed ID: 30146952
11200  Sendai virus C protein limits NO production in infected RAW264.7 macrophages.  Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.  Innate Immun  2018  24(7):430-438  PubMed ID: 30189760
11074  Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.  Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.  J. Biol. Chem.  2018  293(26):10186-10201  PubMed ID: 29760187
11112  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.  Biochem. Pharmacol.  2018  155:182-197  PubMed ID: 29940171
11249  2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.  Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S.  Food Chem. Toxicol.  2018    PubMed ID: 30316843
11279  Characterization of polysaccharide from Helicteres angustifolia L. and its immunomodulatory activities on macrophages RAW264.7.  Sun S, Li K, Xiao L, Lei Z, Zhang Z.  Biomed. Pharmacother.  2019    PubMed ID: 30396084
11335  The effect of mesenchymal stem cells on osteoclast precursor cell differentiation.  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Ando K, Tanimoto K.  J Oral Sci  2019    PubMed ID: 30541990
11493  Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice.  Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Polymers (Basel)  2018  10(12)  PubMed ID: 30961309
11349  5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages.  Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura SI.  BMC Immunol.  2018    PubMed ID: 30567499
11361  Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization.  Islam Z, Inui T, Ishibashi O.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30595385
11380  Liposomes with temperature-responsive reversible surface properties.  Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H.  Colloids Surf B Biointerfaces  2019    PubMed ID: 30641302
11396  Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.  Yoshinaga N, Uchida S, Naito M, Osada K, Cabral H, Kataoka K.  Biomaterials  2019    PubMed ID: 30669016
11383  Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors.  Manabe Y, Hirata T, Sugawara T.  J Oleo Sci  2019    PubMed ID: 30651415
11389  Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers.  Wang W, Nakashima KI, Hirai T, Inoue M.  J Nat Med  2019    PubMed ID: 30656541
11457  Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells.  Takahashi S, Yoshida M, Watanabe MM, Isoda H.  Biomed Res Int  2019    PubMed ID: 30809537
11437  Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin.  Yanagihara Y, Inoue K, Saeki N, Sawada Y, Yoshida S, Lee J, Iimura T, Imai Y.  Bone  2019    PubMed ID: 30771488
11454  In vitro activity and mode of action of phenolic compounds on Leishmania donovani.  Antwi CA, Amisigo CM, Adjimani JP, Gwira TM.  PLoS Negl Trop Dis  2019    PubMed ID: 30802252
11477  Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.  Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T.  Cell Chem Biol  2019    PubMed ID: 30853417
4441  Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels  Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi  Trends in Immunotherapy  2018  2 
4324  Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages.  Quan H, Kim Y, Park HC, Yang HC.  J Biomed Mater Res A  2018    PubMed ID: 29781181
4325  Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.  Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K.  Int J Nanomedicine  2018    PubMed ID: 30122920
4326  Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells.  Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30301531
4327  Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull.  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K.  J Dent Sci  2018    PubMed ID: 30895145
4328  The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells.  Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K.  J Oral Sci  2018    PubMed ID: 29925706
4329  Mechanisms involved in enhancement of osteoclast formation by activin-A.  Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T.  J. Cell. Biochem.  2018    PubMed ID: 29737562
4330  Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.  Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.  Int. Immunopharmacol.  2018    PubMed ID: 30005227
4331  New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella.  El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S.  Fitoterapia  2018    PubMed ID: 29729401
4332  Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.  Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K.  Oxid Med Cell Longev  2018    PubMed ID: 30533177
4333  Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis.  Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H.  Biosci. Biotechnol. Biochem.  2018    PubMed ID: 29165050
4334  Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.  Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y.  Cancer Sci.  2018    PubMed ID: 29444368
4335  Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase.  Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N.  Biochim Biophys Acta Mol Cell Biol Lipids  2018    PubMed ID: 29447909
4336  Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells.  Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H.  Front Physiol  2018    PubMed ID: 30319432
4496  Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.  Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ.  Bone  2018  116:232-247  PubMed ID: 30125729
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4498  Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide.  Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H.  Biochem. Cell Biol.  2018  96(6):769-776  PubMed ID: 29958095
4499  Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.  Choodej S, Pudhom K, Mitsunaga T.  Planta Med.  2018  84(5):329-335  PubMed ID: 28962049
4526  Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells  Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata  Mutation Research/Genetic Toxicology and Environmental Mutagenesis  2017  818, 7-16  PubMed ID: 28477879
4881  Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.  Honda H, Nagai Y, Matsunaga T, Saitoh S, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A, Takatsu K.  J Leukoc Biol  2012  91(6):967-76  PubMed ID: 22422925
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5357  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.  Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.  Mol Cell  2019  76(5):797-810  PubMed ID: 31606272
5375  Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy.  Nishida K, Kuchiiwa S, Oiso S, Futagawa T, Masuda S, Takeda Y, Yamada K.  Cancer Sci  2008  99(8):1618-25  PubMed ID: 18754875
5417  Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage.  Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N.  J Transl Med  2012  10:80  PubMed ID: 22546323
5424  Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells  Takeshi KAWAHARA, Daichi NAKAYAMA, Keisuke TODA, Shyuichiro INAGAKI, Katsumi TANAKA, Hisako YASUI  Food Sci. Technol. Res  2013  19 (6), 1019 – 1027 
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6334  Antimicrobial and anti-inflammatory properties of nostocionone isolated from Nostoc commune Vauch and its derivatives against Propionibacterium acnes.  Itoh T, Tsuchida A, Muramatsu Y, Ninomiya M, Ando M, Tsukamasa Y, Koketsu M.  Anaerobe  2014  27:56-63  PubMed ID: 24699048
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6477  Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).  Ogasawara T, Katagiri M, Yamamoto A, Hoshi K, Takato T, Nakamura K, Tanaka S, Okayama H, Kawaguchi H.  J Bone Miner Res  2004  19(7):1128-36  PubMed ID: 15176996
11498  Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques.  Narita Y, Shimizu K, Ikemoto K, Uchino R, Kosugi M, Maess MB, Magata Y, Oku N, Ogawa M.  J Control Release  2019    PubMed ID: 30936020
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