細胞番号 : 細胞名
RCB0483 : LA-N-1
update : 2023/06/30
|
| 細胞特性(Comment:英) | Human cell line derived from Neuroblastoma. N-myc gene is amplified. Derived from metastatic tumor in bone marrow. |
| 細胞特性(日) | ヒト神経芽細胞腫由来細胞株。N-myc遺伝子の増幅がある。骨髄転移巣由来。 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | Non-profit institutions only. |
| 使用条件(日) | 非営利機関に限る。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
|
|
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
|
| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
|
|
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
|
| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
|
細胞基本情報
|
|
寄託者 |
Nishi, Yoshisuke
|
| 樹立者 |
Seeger, Robert C.
|
| 寄託日 |
1990
|
| 動物種 |
_human
< Mammals
|
| 属名 |
Homo
|
| 種名 |
sapiens
|
| 性別 |
Male
|
| 齢 |
2 years
|
| 採取組織 |
bone marrow
|
| 病名 |
neuroblastoma (stage IV)
|
| 転移 |
Yes
|
| 転移巣 |
bone marrow
|
| 細胞分類 |
cancer
|
| 入手歴 |
Latt, S. A.
|
|
細胞寿命 |
infinite
|
| 細胞形態 |
other
|
| Cellosaurus(Expasy) |
CVCL_1827
|
|
細胞培養・検査情報
| |
寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
|
培養形態 |
|
Adherent cells
|
| 培地 |
|
RPMI1640 + 10% FBS
|
| 抗生物質 |
|
Free
|
|
継代方法 |
|
0.25% Trypsin (1min.) or pipetting
|
|
継代密度 |
|
1 : 8 split
|
| 継代・培地交換頻度 |
|
Subculture : once/week, Medium Renewal : 2 times/week
|
| 培養最適温度 |
|
37
℃
|
| 二酸化炭素濃度 |
|
5
%
|
| 凍結培地 |
|
Medium + 10% DMSO
|
| 凍結方法 |
|
Slow freezing
|
| マイコプラズマ |
|
(-)
|
| ウィルス（HIV) |
|
(-)
|
| アイソザイム検査 |
|
LD, NP
|
| 染色体検査 |
|
69-83(50) : /78(3),79(3),80(3),81(13),82(18),83(5)
|
| 個体識別検査 |
|
OK
|
| 画像情報 |
寄託時情報 | ロット情報 |
|
|
|
| 文献情報 |
Reference(英) |
8件
|
| Reference(日) |
0件
|
| 利用者成果(英) |
11件
|
| 利用者成果(日) |
0件
|
| Reference(英) |
|
4701
Chen RL1, Reynolds CP, Seeger RC.
Neutrophils are cytotoxic and growth-inhibiting for neuroblastoma cells with an anti-GD2 antibody but, without cytotoxicity, can be growth-stimulating.
Cancer Immunol Immunother.
2000
48(11):603-12
PubMed ID: 10663607
DOI: 10.1007/s002620050008
|
|
247
Uçar K, Seeger RC, Challita PM, Watanabe CT, Yen TL, Morgan JP, Amado R, Chou E, McCallister T, Barber JR, et al.
Sustained cytokine production and immunophenotypic changes in human neuroblastoma cell lines transduced with a human gamma interferon vector
Cancer Gene Ther
1995
2(3):171-81
PubMed ID: 8528960
|
|
1287
Gilbert F, Feder M, Balaban G, Brangman D, Lurie, D K, Podolsky R, Rinaldt V, Vinikoor N, Weisband J
Human neuroblastomas and abnormalities of chromosomes 1 and 17.
Cancer Res
1984
44:5444-9
PubMed ID: 6488196
|
|
4697
Sidell N, Altman A, Haussler MR, Seeger RC.
Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines.
Exp Cell Res
1983
148(1):21-30
PubMed ID: 6313408
DOI: 10.1016/0014-4827(83)90184-2
|
|
4695
Danon YL, Epstein MB, Siegel MM, Rucker N, Myers CP, Norman A, Benedict WF, Seeger RC.
Variability in DNA distributions of human neuroblastomas after cyclophosphamide.
Cancer Treat Rep
1980
64(12):1275-81
PubMed ID: 7471116
|
|
4696
Siegel MM, Chung HS, Rucker N, Siegel SE, Seeger RC, Isaacs H Jr, Benedict WF.
In vitro and in vivo preclinical chemotherapy studies of human neuroblastoma.
Cancer Treat Rep
1980
64(8-9):975-9
PubMed ID: 7448832
|
|
1122
Seeger, R C, Rayner, S A, Banerjee A, Chung H, Laug, W E, Neustein, H B, Benedict, W F
Morphology, growth, chromosomal pattern and fibrinolytic activity of two new human neuroblastoma cell lines.
Cancer Res
1977
37:1364-71
PubMed ID: 856461
|
|
4694
West GJ, Uki J, Herschman HR, Seeger RC.
Adrenergic, cholinergic, and inactive human neuroblastoma cell lines with the action-potential Na+ ionophore.
Cancer Res
1977
37(5):1372-6
PubMed ID: 15722
|
| 利用者成果(英) |
|
21143
Ma G, Tan C, Shan Y, Shao N, Wang F, Dimitrov DS, Wang L, Zhao Q.
An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth.
J Cancer
2022
13(6):1830-1836
PubMed ID: 35399718
DOI: 10.7150/jca.69064
|
|
10728
Kurita M, Takada T, Wakabayashi N, Asami S, Ono S, Uchiyama T, Suzuki T.
Antitumor Effect of Burchellin Derivatives Against Neuroblastoma.
Anticancer Res.
2018
38:855-862
PubMed ID: 29374712
DOI: 10.21873/anticanres.12294
|
|
14467
Tabata K, Nishimura Y, Takeda T, Kurita M, Uchiyama T, Suzuki T.
Sesquiterpene lactones derived from Saussurea lappa induce apoptosis and inhibit invasion and migration in neuroblastoma cells
J Pharmacol Sci
2015
127(4):397-403
PubMed ID: 25953266
DOI: 10.1016/j.jphs.2015.01.002
|
|
15018
So WW, Liu WN, Leung KN.
Omega-3 Polyunsaturated Fatty Acids Trigger Cell Cycle Arrest and Induce Apoptosis in Human Neuroblastoma LA-N-1 Cells
Nutrients
2015
7(8):6956-73
PubMed ID: 26295255
DOI: 10.3390/nu7085319
|
|
18238
Liao X, Leung KN.
Tryptanthrin induces growth inhibition and neuronal differentiation in the human neuroblastoma LA-N-1 cells
Chem Biol Interact
2013
203(2):512-21
PubMed ID: 23500671
DOI: 10.1016/j.cbi.2013.03.001
|
|
12725
Kitano T, Yoda H, Tabata K, Miura M, Toriyama M, Motohashi S, Suzuki T.
Vitamin K3 analogs induce selective tumor cytotoxicity in neuroblastoma
Biol Pharm Bull
2012
35(4):617-23
PubMed ID: 22466570
DOI: 10.1248/bpb.35.617
|
|
15082
Tabata K, Kim M, Makino M, Satoh M, Satoh Y, Suzuki T.
Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells
Anticancer Res
2012
32(11):4781-9
PubMed ID: 23155243
|
|
7941
Hayama T, Tabata K, Uchiyama T, Fujimoto Y, Suzuki T.
Ferrearin C induces apoptosis via heme oxygenase-1 (HO-1) induction in neuroblastoma.
J Nat Med
2011
65:431-9
PubMed ID: 21327520
DOI: 10.1007/s11418-011-0514-1
|
|
9486
F H Lo, N K Mak, K N Leung
Studies on the Anti-Tumor Activities of the Soy Isoflavone Daidzein on Murine Neuroblastoma Cells
Biomed Pharmacother
2007
61(9):591-5
PubMed ID: 17905565
DOI: 10.1016/j.biopha.2007.08.021
|
|
17984
Nishimura E, Sasaki K, Maruyama K, Tsukada T, Yamaguchi K.
Decrease in neuron-restrictive silencer factor (NRSF) mRNA levels during differentiation of cultured neuroblastoma cells
Neurosci Lett
1996
211(2):101-4
PubMed ID: 8830854
DOI: 10.1016/0304-3940(96)12722-1
|
|
1969
Maruyama K, Tsukada T, Bandoh S, Sasaki K, Ohkura N, Yamaguchi K
Expression of NOR-1 and its closely related members of the steroid/thyroid hormone receptor superfamily in human neuroblastoma cell lines.
Cancer Lett
1995
96:117-22
PubMed ID: 7553599
DOI: 10.1016/0304-3835(95)03921-i
|
戻る
細胞材料の再培養方法 (
HPS以外・
HPS )
ページトップへ
細胞材料開発室サイト
