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RCB0467 : Lu-134-B  update : 2018/07/31
CommentSmall cell carcinoma, classic type. See Lu-134-A. Application consideration
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC( regarding any kind of for-profit use.
Basic information Depositor Terasaki, Takeo
Originator Terasaki, T. & Shimosato, Y.
Year of deposit 1990
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Male
Age at sampling 80 years
Tissue lung
Case history small cell carcinoma
Classification cancer
Year of origin 1982
Lifespan infinite
Morphology other
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 2 split
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 48-93(50) : /61(5),62(5),63(6),64(9),65(9),66(2)/
Reference information Reference 9
User's Publication 5

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1368  Matsumoto T, Terasaki T, Mukai K, Wada M, Okamoto A, Yokota J, Yamaguchi K, Kato K, Nagatsu T, Shimosato Y  Relation between nucleolar size and growth characteristics in small cell lung cancer cell lines.  Jpn J Cancer Res   1991  82:820-8  PubMed ID: 1715338
1320  Terasaki T, Shimosato Y, Wada M, Yokota J, Terada M  Selection of Radioresistant Cell by Vitamin A Deficiency in a Small Cell Lung Cancer Cell Line  Jpn J Cancer Res  1990  81:780-785  PubMed ID: 2168867
1114  Terasaki T, Shimosato Y, Nakajima T, Tsumuraya M, Ichinose H, Nagatsu T, Kato K  Reversible squamous cell characteristics induced by vitamin A deficiency in a small cell lung cancer cell line.  Cancer Res  1987  47:3533-7  PubMed ID: 2438038
3142  Nakagawa K, Yokota J, Wada M, Sasaki Y, Fujiwara Y, Sakai M, Muramatsu M, Terasaki T, Tsunokawa Y, Terada M, et al.  Levels of glutathione S transferase pi mRNA in human lung cancer cell lines correlate with the resistance to cisplatin and carboplatin.  Jpn J Cancer Res  1988  79:301-4  PubMed ID: 2836347
1118  Terasaki T, Shimosato Y, Nakajima T, Tsumuraya M, Morinaga S, Hirohashi S, Yamaguchi K, Kato K, Ichinose H, Nagatsu T  Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.  Jpn J Clin Oncol  1986  16:203-12  PubMed ID: 3022030
735  Terasaki T, Kameya T, Nakajima T, Tsumuraya M, Shimosato Y, Kato K, Ichinose H, Nagatsu T, Hasegawa T  Interconversion of biological characteristics of small cell lung cancer depending on culture conditions.  Gann  1984  75:1089-99  PubMed ID: 6098504
3144  Shimoyama Y, Gotoh M, Terasaki T, Kitajima M, Hirohashi S  Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells.  Cancer Res  1995  55:2206-11  PubMed ID: 7743525
3140  Koh T, Yokota J, Ookawa K, Kina T, Koshimura K, Miwa S, Ariyasu T, Yamada H, Osaka M, Haga H, et al.  Alternative splicing of the neurofibromatosis 1 gene correlates with growth patterns and neuroendocrine properties of human small-cell lung-carcinoma cells.  Int J Cancer  1995  60:843-7  PubMed ID: 7896456
3150  Tanaka K, Terasaki T  Development and elongation of neurite-like outgrowth on small cell lung cancer cell lines  Oncogene  1997  88:176-183  PubMed ID: 9119746

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User's Publication
3094  Kaneda, Atsushi, Wakazono, Kuniko, Tsukamoto, Tetsuya, Watanabe, Naoko, Yagi, Yukiko, Tatematsu, Masae, Kaminishi, Michio, Sugimura, Takashi, Ushijima, Toshikazu  Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.  Cancer Res  2004  64:6410-5  PubMed ID: 15374948
8174  Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K.  Identification of thymidylate synthase as a potential therapeutic target for lung cancer.  Br. J. Cancer  2010  103:354-61  PubMed ID: 20628382
11097  Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnstrom H, Micke P, Nagase T, Saito A.  An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer.  J. Pathol.  2018    PubMed ID: 29876935
6407  Matsushima Y, Kinoshita Y, Nakata H, Inomoto-Naribayashi Y, Asahara M, Kawanami C, Nakamura A, Ito M, Matsui T, Fujiwara T, et al.  Gastrin receptor gene expression in several human carcinomas.  Jpn J Cancer Res  1994  85(8):819-24  PubMed ID: 7928627
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309

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