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RCB0455 : LC-1/sq  update : 2018/08/14
CommentLung Cancer-1/squamous. Parent cell line of RCB0438 LC-1/sq-SF, the same patient as RCB0439 LC-F. Cell growth is slow.
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Itoh, Hiroshi
Originator Kataoka, Hiroaki
Year of deposit 1989
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Male
Age at sampling 69 years
Tissue lung
Classification cancer
Year of origin 1986
History H. Kataoka
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives (HamF12 : RPMI1640 = 1 : 1) + 25mM HEPES + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/1-2 weeks, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR (human) OK
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 82-467(50) : /94(3),95(7),96(7),97(2),98(2),99(4)/
Images
deposit info
lot info
Reference information Reference 1
User's Publication 9


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Reference
1779  Itoh H, Kataoka H, Koita H, Nabeshima K, Inoue T, Kangawa K, Koono M  Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.  Int J Cancer  1991  49:436-43  PubMed ID: 1917142

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User's Publication
3028  Tajima K, Demachi A, Ito Y, Nishida K, Akatsuka Y, Tsujimura K, Kuwano H, Mitsudomi T, Takahashi T, Kuzushima K  Identification of an epitope from the epithelial cell adhesion molecule eliciting HLA-A*2402-restricted cytotoxic T-lymphocyte responses.  Tissue Antigens  2004  64:650-9  PubMed ID: 15546337
3113  Yoshimasu, Tatsuya, Sakurai, Teruhisa, Oura, Shoji, Hirai, Issei, Tanino, Hirokazu, Kokawa, Yozo, Naito, Yasuaki, Okamura, Yoshitaka, Ota, Ichiro, Tani, Naoyuki, Matsuura, Nariaki  Increased expression of integrin alpha3beta1 in highly brain metastatic subclone of a human non-small cell lung cancer cell line.  Cancer Sci  2004  95:142-8  PubMed ID: 14965364
3027  Tajima, Kouhei, Ito, Yoshinori, Demachi, Ayako, Nishida, Keiko, Akatsuka, Yoshiki, Tsujimura, Kunio, Hida, Toyoaki, Morishima, Yasuo, Kuwano, Hiroyuki, Mitsudomi, Tetsuya, Takahashi, Toshitada, Kuzushima, Kiyotaka  Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes.  Int J Cancer  2004  110:403-12  PubMed ID: 15095306
3338  Seike, Masahiro, Kondo, Tadashi, Fujii, Kazuyasu, Yamada, Tesshi, Gemma, Akihiko, Kudoh, Shoji, Hirohashi, Setsuo  Proteomic signature of human cancer cells.  Proteomics  2004  4:2776-88  PubMed ID: 15352251
3094  Kaneda, Atsushi, Wakazono, Kuniko, Tsukamoto, Tetsuya, Watanabe, Naoko, Yagi, Yukiko, Tatematsu, Masae, Kaminishi, Michio, Sugimura, Takashi, Ushijima, Toshikazu  Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.  Cancer Res  2004  64:6410-5  PubMed ID: 15374948
9522  Nishijima N, Seike M, Soeno C, Chiba M, Miyanaga A, Noro R, Sugano T, Matsumoto M, Kubota K, Gemma A.  miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.  Int. J. Oncol.  2016  48:937-44  PubMed ID: 26783187
9887  Ye X, Zhou Q, Matsumoto Y, Moriyama M, Kageyama S, Komatsu M, Satoh S, Tsuchida M, Saijo Y.  Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.  Anticancer Res.  2016  36:6021-6029  PubMed ID: 27793929
11379  Omoto K, Matsuda R, Nakai Y, Tatsumi Y, Nakazawa T, Tanaka Y, Shida Y, Murakami T, Nishimura F, Nakagawa I, Motoyama Y, Nakamura M, Fujimoto K, Hiroyuki N.  Expression of peptide transporter 1 has a positive correlation in protoporphyrin IX accumulation induced by 5-aminolevulinic acid with photodynamic detection of non-small cell lung cancer and metastatic brain tumor specimens originating from non-small cell lung cancer.  Photodiagnosis Photodyn Ther  2019    PubMed ID: 30639584
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309



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