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Cell No. : Cell Name
RCB0435 : U-937 DE-4  update : 2024/03/14
CommentCloned U-937, differentiate with TNF
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Iwamoto, Sanju
Originator Sundstrom, C. & Nilsson, K.
Year of deposit 1990
Another name DE-4
Original cell U-937
Animal _human < Mammals
Genus Homo
Species sapiens
Gender Male
Age at sampling 37 years
Tissue pleural effusion
Disease name histiocyte lymphoma
Classification cancer
History J. Minowada (RPMI)
Memo_1 Mycoplasma was eliminated with MC-210.
Lifespan infinite
Morphology lymphocyte-like
Cellosaurus(Expasy) CVCL_8765
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Culture medium RPMI1640 + 10% FBS
Culture method
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 10 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Virus (HTLV-1) (-)
Isozyme LD, NP
Chromosome mode 40-62(50) : /49(3),50(5),51(10),52(6),53(6),54(5)/
STR(human) OK
Reference information Reference 8
User's Publication 67


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Reference
3507  Biochem Biophys Res Commun  Lymphotoxin lacks effects on 75-kDa receptors in cytotoxicity on U-937 cells.  Iwamoto S, Shibuya I, Takeda K, Takeda M.  1994  199(1):70-7  PubMed ID: 8123048   DOI: 10.1006/bbrc.1994.1195
3505  Iwamoto S, Takeda K, Kamijo R, Konno K.  Induction of resistance to TNF cytotoxicity and mitochondrial superoxide dismutase on U-937 cells by 1,25-dihydroxyvitamin D3.  Biochem Biophys Res Commun  1990  170(1):73-9  PubMed ID: 2372299   DOI: 10.1016/0006-291x(90)91242-k
3506  Iwanami M, Takeda K, Iwamoto S, Konno K.  Combination effects of interferon-gamma and cholera toxin on induction of differentiation of an insensitive U-937 clone.  Jpn J Cancer Res  1990  81(5):520-6  PubMed ID: 2166023   DOI: 10.1111/j.1349-7006.1990.tb02601.x
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194  Nilsson K, Andersson Lc, Gahmberg CG.  Cell surface characteristics of human histiocytic lymhoma lines--I. Surface glycoprotein patterns  Leuk Res  1980  4(3):271-7.  PubMed ID: 6997636   DOI: 10.1016/0145-2126(80)90034-x
1142  Koren, H S, Anderson, S J, Larrick, J W  In vitro activation of a human macrophage-like cell line.  Nature  1979  279:328-31  PubMed ID: 450085   DOI: 10.1038/279328a0
1141  Ralph P, Moore, M A, Nilsson K  Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines.  J Exp Med  1976  143:1528-33  PubMed ID: 1083890   DOI: 10.1084/jem.143.6.1528
193  Sundström C, Nilsson K.  Establishment and characterization of a human histiocytic lymphoma cell line (U-937)  Int J Cancer  1976  17(5):565-77.  PubMed ID: 178611   DOI: 10.1002/ijc.2910170504

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User's Publication
19788  Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi  Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells  Fundamental Toxicological Sciences  2023  10:233-240    DOI: 10.2131/fts.10.233
19927  Ishihara T, Tanaka KI, Takafuji A, Miura K, Mizushima T.  Attenuation of LPS-Induced Lung Injury by Benziodarone via Reactive Oxygen Species Reduction  Int J Mol Sci  2023  24(12):10035  PubMed ID: 37373184   DOI: 10.3390/ijms241210035
17511  Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi  Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells  Fundamental Toxicological Sciences  2022  9:151-157    DOI: 10.2131/fts.9.151
20451  Phan TKT, Do TL, Tachibana K, Kihara T.  Alpha-mangostin dephosphorylates ERM to induce adhesion and decrease surface stiffness in KG-1 cells.  Hum Cell  2022    PubMed ID: 34817798   DOI: 10.1007/s13577-021-00651-8
17332  Kikuchi H, Harata K, Akiyoshi S, Sagara T, Madhyastha H, Kuribayashi F.  Potential role of green tea amino acid l-theanine in the activation of innate immune response by enhancing expression of cytochrome b558 responsible for the reactive oxygen species-generating ability of leukocytes  Microbiol Immunol  2022  66(6):342-349  PubMed ID: 35338668   DOI: 10.1111/1348-0421.12977
14198  Zha S, Ueno M, Liang Y, Okada S, Oda T, Ishibashi F.  Induction of Apoptotic Cell Death in Human Leukemia U937 Cells by C18 Hydroxy Unsaturated Fatty Acid Isolated from Red Alga Tricleocarpa jejuensis  Mar Drugs  2021  19(3):138  PubMed ID: 33801204   DOI: 10.3390/md19030138
14477  Zhao Y, Zhu XY, Song T, Zhang L, Eirin A, Conley S, Tang H, Saadiq I, Jordan K, Lerman A, Lerman LO.  Mesenchymal stem cells protect renal tubular cells via TSG-6 regulating macrophage function and phenotype switching  Am J Physiol Renal Physiol  2021  320(3):F454-F463  PubMed ID: 33554782   DOI: 10.1152/ajprenal.00426.2020
20265  Kikuchi H, Harata K, Madhyastha H, Kuribayashi F.  Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells.  Biochem Biophys Rep  2021  25:100891  PubMed ID: 33490645   DOI: 10.1016/j.bbrep.2020.100891
14475  Hidehiko Kikuchi, Kaori Harata, Chikage Kawai, Harishkumar Madhyastha, Akira Yamauchi, Futoshi Kuribayashi  Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils  Fundamental Toxicological Sciences  2020  7:201-206    DOI: 10.2131/fts.7.201
6891  Sumiko Akiyoshi, Hidehiko Kikuchi, Futoshi Kuribayashi, Harishkumar Madhyastha, Hisanori Minami  Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells  Fundamental Toxicological Sciences  2019  6:319-325    DOI: 10.2131/fts.6.319
9138  Aki Kawano, Wataru Ariyoshi, Yoshie Yoshioka, Hisako Hikiji, Tatsuji Nishihara, Toshinori Okinaga  Docosahexaenoic Acid Enhances M2 Macrophage Polarization via the p38 Signaling Pathway and Autophagy  J Cell Biochem  2019  120 (8), 12604-12617  PubMed ID: 30825233   DOI: 10.1002/jcb.28527
9810  Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda  Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves  Plant Signal Behav  2019  14(10):e1644594  PubMed ID: 31342859   DOI: 10.1080/15592324.2019.1644594
10626  Kikuchi H, Mimuro H, Kuribayashi F.  Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells.  Biochem. Biophys. Res. Commun.  2018  495:1195-1200  PubMed ID: 29183727   DOI: 10.1016/j.bbrc.2017.11.161
4445  Hidehiko Kikuchi, Futoshi Kuribayashi, Harishkumar Madhyastha  Positions and numbers of hydroxyl groups in hydroxychalcone derivatives are involved in cytotoxicity against human monoblastic U937 cells  Fundamental Toxicological Sciences  2018  5, 149-152    DOI: 10.2131/fts.5.149
14353  Pang L, Han S, Jiao Y, Jiang S, He X, Li P.  Bu Fei Decoction attenuates the tumor associated macrophage stimulated proliferation, migration, invasion and immunosuppression of non-small cell lung cancer, partially via IL-10 and PD-L1 regulation  Int J Oncol  2017  Jul;51(1):25-38  PubMed ID: 28534943   DOI: 10.3892/ijo.2017.4014
14457  Okamura Y, Otani K, Sekiguchi A, Kogane T, Kakuda C, Sakamoto Y, Kodama T, Okada M, Yamawaki H.  Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4  Pflugers Arch  2017  469(9):1177-1188  PubMed ID: 28405802   DOI: 10.1007/s00424-017-1976-0
14471  Otsuka M, Okinaga T, Ariyoshi W, Kitamura C, Nishihara T.  Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages  J Cell Biochem  2017  118(10):3308-3317  PubMed ID: 28295583   DOI: 10.1002/jcb.25983
12240  Hirofumi Sawai, Hideo Ogiso, Toshiro Okazaki  Differential changes in sphingolipids between TNF-induced necroptosis and apoptosis in U937 cells and necroptosis-resistant sublines  Leuk Res  2015  39(9):964-70  PubMed ID: 26189109   DOI: 10.1016/j.leukres.2015.06.002
14463  Taniguchi K, Hikiji H, Okinaga T, Hashidate-Yoshida T, Shindou H, Ariyoshi W, Shimizu T, Tominaga K, Nishihara T.  Essential Role of Lysophosphatidylcholine Acyltransferase 3 in the Induction of Macrophage Polarization in PMA-Treated U937 Cells  J Cell Biochem  2015  116(12):2840-8  PubMed ID: 25994902   DOI: 10.1002/jcb.25230
15533  Masahito Miki, Masafumi Morita  Evaluation of the Biocompatibility of a Ti-Ta-Sn Alloy Using Cell Cultures.  Materials Transactions  2015  56:1087-109    DOI: 10.2320/matertrans.M2015062
17135  Tomoki Nishiguchi, Zedong Jiang, Mikinori Ueno, Satoshi Takeshita, Kichul Cho, Seong Woon Roh, Kyong-Hwa Kang, Kenichi Yamaguchi, Daekyung Kim, Tatsuya Oda  Reevaluation of bactericidal, cytotoxic, and macrophage-stimulating activities of commercially available Fucus vesiculosus fucoidan  ALGAE  2014  29:237-247    DOI: 10.4490/algae.2014.29.3.237
4993  Tsubaki M, Itoh T, Satou T, Imano M, Komai M, Ogawa N, Mukai J, Nishida S.  Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.  Biochem Pharmacol  2013  85(2):163-72  PubMed ID: 23085435   DOI: 10.1016/j.bcp.2012.10.009
13725  Abe K, Ichinomiya R, Kanai T, Yamamoto K.  Effect of a Japanese energy healing method known as Johrei on viability and proliferation of cultured cancer cells in vitro  J Altern Complement Med  2012  18(3):221-8  PubMed ID: 22385045   DOI: 10.1089/acm.2011.0467
7684  Kim SH, Yamamoto T, Fourmy D, Fujii T.  Electroactive microwell arrays for highly efficient single-cell trapping and analysis.  Small  2011  7:3239-47  PubMed ID: 21932278   DOI: 10.1002/smll.201101028
7752  Sawai H, Domae N.  Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells.  Biochem. Biophys. Res. Commun.  2011  411:569-73  PubMed ID: 21763280   DOI: 10.1016/j.bbrc.2011.06.186
7778  Phalitakul S, Okada M, Hara Y, Yamawaki H.  Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells.  Pharmacol. Res.  2011  64:493-500  PubMed ID: 21683791   DOI: 10.1016/j.phrs.2011.06.001
7822  Aida J, Higuchi S, Hasegawa Y, Nagano-Ito M, Hirabayashi Y, Banba A, Shimizu T, Kikuchi A, Saga M, Ichikawa S.  Up-regulation of ceramide glucosyltransferase during the differentiation of U937 cells.  J. Biochem.  2011  150:303-10  PubMed ID: 21558327   DOI: 10.1093/jb/mvr058
7845  Yamawaki H, Kuramoto J, Kameshima S, Usui T, Okada M, Hara Y.  Omentin, a novel adipocytokine inhibits TNF-induced vascular inflammation in human endothelial cells.  Biochem. Biophys. Res. Commun.  2011  408:339-43  PubMed ID: 21514279   DOI: 10.1016/j.bbrc.2011.04.039
7886  Saito Y, Nakahata S, Yamakawa N, Kaneda K, Ichihara E, Suekane A, Morishita K.  CD52 as a molecular target for immunotherapy to treat acute myeloid leukemia with high EVI1 expression.  Leukemia  2011  25:921-31  PubMed ID: 21394097   DOI: 10.1038/leu.2011.36
8227  Tsubosaka Y, Murata T, Yamada K, Uemura D, Hori M, Ozaki H.  Halichlorine reduces monocyte adhesion to endothelium through the suppression of nuclear factor-kappaB activation.  J. Pharmacol. Sci.  2010  113:208-13  PubMed ID: 20562517   DOI: 10.1254/jphs.10065fp
18575  Nozaki H, Yanagida M, Koide K, Shiotani K, Kinoshita M, Kobayashi Y, Watarai S, Nakamura K, Suzuki A, Ariga T, Kushi Y.  Production and characterization of monoclonal antibodies specific to lactotriaosylceramide  Glycobiology  2010  20(12):1631-42  PubMed ID: 20693232   DOI: 10.1093/glycob/cwq117
4869  Kitagawa J, Hara T, Tsurumi H, Kanemura N, Kasahara S, Shimizu M, Moriwaki H.  Cell cycle-dependent priming action of granulocyte colony-stimulating factor (G-CSF) enhances in vitro apoptosis induction by cytarabine and etoposide in leukemia cell lines.  J Clin Exp Hematop  2010  50(2):99-105  PubMed ID: 21123967   DOI: 10.3960/jslrt.50.99
6125  Shimahara A, Yamakawa N, Nishikata I, Morishita K.  Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2.  J Biol Chem  2010  285(22):16967-77  PubMed ID: 20363750   DOI: 10.1074/jbc.M110.102046
8505  Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Astrocyte elevated gene-1 (AEG-1) is induced by lipopolysaccharide as toll-like receptor 4 (TLR4) ligand and regulates TLR4 signalling.  Immunology  2009  128:e700-6  PubMed ID: 19740331   DOI: 10.1111/j.1365-2567.2009.03063.x
8579  Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M.  Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells.  J. Steroid Biochem. Mol. Biol.  2009  114:144-51  PubMed ID: 19429444   DOI: 10.1016/j.jsbmb.2009.01.022
8602  Nakayasu S, Soegima R, Yamaguchi K, Oda T.  Biological activities of fucose-containing polysaccharide ascophyllan isolated from the brown alga Ascophyllum nodosum.  Biosci. Biotechnol. Biochem.  2009  73:961-4  PubMed ID: 19352011   DOI: 10.1271/bbb.80845
6436  Hisao Haniu, Yoshikazu Matsuda, Kenji Takeuchi  Potential of a Novel Safety Evaluation of Nanomaterials Using a Proteomic Approach  Journal of Health Science  2009  55:428-434    DOI: 10.1248/jhs.55.428
6804  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivatio  Biochem Biophys Res Commun  2008  374(4):683-7  PubMed ID: 18662673   DOI: 10.1016/j.bbrc.2008.07.090
9068  Yasuhiro Yamasaki, Daisuke Katsuo, Seiichiro Nakayasu, Cristina Salati, JingJing Duan, Yanan Zou, Yukihiko Matsuyama, Kenichi Yamaguchi, Tatsuya Oda  Purification and Characterization of a Novel High Molecular Weight Exotoxin Produced by Red Tide Phytoplankton, Alexandrium Tamarense  J Biochem Mol Toxicol  2008  22 (6), 405-15  PubMed ID: 19111002   DOI: 10.1002/jbt.20253
16902  Fujita K, Tsujimura A, Miyagawa Y, Kiuchi H, Matsuoka Y, Takao T, Takada S, Nonomura N, Okuyama A.  Isolation of germ cells from leukemia and lymphoma cells in a human in vitro model: potential clinical application for restoring human fertility after anticancer therapy  Cancer Res  2006  66(23):11166-71  PubMed ID: 17145860   DOI: 10.1158/0008-5472.CAN-06-2326
2808  Pang, Zhongcun, Otaka, Kodo, Maoka, Takashi, Hidaka, Kumi, Ishijima, Sumio, Oda, Masayuki, Ohnishi, Masatake  Structure of beta-glucan oligomer from laminarin and its effect on human monocytes to inhibit the proliferation of U937 cells.  Biosci Biotechnol Biochem  2005  69:553-8  PubMed ID: 15784984   DOI: 10.1271/bbb.69.553
3270  Inamura J, Ikuta K, Jimbo J, Shindo M, Sato K, Torimoto Y, Kohgo Y.  Upregulation of hepcidin by interleukin-1beta in human hepatoma cell lines.  Hepatol. Res.  2005  33:198-205  PubMed ID: 16198622   DOI: 10.1016/j.hepres.2005.08.005
9048  Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye  Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines  J Agric Food Chem  2005  53 (16), 6313-8  PubMed ID: 16076112   DOI: 10.1021/jf0506129
12837  Fujita H, Utsumi T, Muranaka S, Ogino T, Yano H, Akiyama J, Yasuda T, Utsumi K.  Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B  Biochem Pharmacol  2005  69(12):1773-84.  PubMed ID: 15869745   DOI: 10.1016/j.bcp.2005.03.006
15551  Hirohisa Matsushita, Hiroaki Kuwabara, Satoko Ishikawa, Masataka Mochizuki  Apoptosis Induced in Human Cell Lines by a Butanol Extract from Chlorophytum comosum Roots  Journal of Health Science  2005  51:341-345    DOI: 10.1248/jhs.51.341
2848  Feng, Xingmin, Chuhjo, Tatsuya, Sugimori, Chiharu, Kotani, Takeharu, Lu, Xuzhang, Takami, Akiyoshi, Takamatsu, Hiroyuki, Yamazaki, Hirohito, Nakao, Shinji  Diazepam-binding inhibitor-related protein 1: a candidate autoantigen in acquired aplastic anemia patients harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells.  Blood  2004  104:2425-31  PubMed ID: 15217832   DOI: 10.1182/blood-2004-05-1839
5409  Fukushima K, Ishiyama C, Yamashita K.  Recognition by TNF-alpha of the GPI-anchor glycan induces apoptosis of U937 cells.  Arch Biochem Biophys  2004  426(2):298-305  PubMed ID: 15158680   DOI: 10.1016/j.abb.2004.02.028
13883  Kobayashi H, Takemura Y, Hayashi T, Ujiiye T, Kawase M, Niino Y, Miyachi H, Ohshima T, Hotta T.  Expression level of MDR1 message in peripheral blood leukocytes from healthy adults: a competitive nucleic acid sequence-based amplification assay for its determination  Clin Chem Lab Med  2004  42(10):1098-101  PubMed ID: 15552266   DOI: 10.1515/CCLM.2004.226
2662  Akiyama, Hidehiko, Ino, Teruo, Tokunaga, Etsuko, Katsuda, Itsurou, Ezaki, Kohji  A synergistic increase of apoptosis utilizing Fas antigen expression induced by low doses of anticancer drug.  Rinsho Byori  2003  51:733-9  PubMed ID: 13677932  
18798  Bamba H, Ota S, Kato A, Miyatani H, Kawamoto C, Yoshida Y, Fujiwara K.  Effect of rebamipide on prostaglandin receptors-mediated increase of inflammatory cytokine production by macrophages  Aliment Pharmacol Ther  2003  Suppl 1:113-8  PubMed ID: 12925148   DOI: 10.1046/j.1365-2036.18.s1.13.x
3979  Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M, Nozawa Y.  Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.  J Nat Prod  2003  66(8):1124-7  PubMed ID: 12932141   DOI: 10.1021/np020546u
6708  Hikasa M, Yamamoto E, Kawasaki H, Komai K, Shiozawa K, Hashiramoto A, Miura Y, Shiozawa S.  p21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients.  Biochem Biophys Res Commun  2003  304(1):143-7  PubMed ID: 12705898   DOI: 10.1016/s0006-291x(03)00574-6
15544  MAKOTO NOGUCHI, ICHIRO ARIFUKU, AKIMICHI YAMASHITA, KENZO SATO  Induction of hepatocyte growth factor and inhibition of proliferationby extracellular matrix component derived from fish skin of Reinhararditushippoglossoides  Fisheries Science  2003  69:401-407    DOI: 10.1046/j.1444-2906.2003.00635.x
2549  Nagai, Fusako, Hiyoshi, Yasuko, Sugimachi, Kumiko, Tamura, Hiro-Omi  Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines.  Biol Pharm Bull  2002  25:383-5  PubMed ID: 11913539   DOI: 10.1248/bpb.25.383
17078  Hashizume K, Hatanaka Y, Fukuda I, Sano T, Yamaguchi Y, Tani Y, Danno G, Suzuki K, Ashida H.  N-acetyl-L-cysteine suppresses constitutive expression of CD11a/LFA-1alpha protein in myeloid lineage  Leuk Res  2002  26(10):939-44  PubMed ID: 12163056   DOI: 10.1016/s0145-2126(02)00037-1
9032  N Kiyokawa, T Mori, T Taguchi, M Saito, K Mimori, T Suzuki, T Sekino, N Sato, H Nakajima, Y U Katagiri, T Takeda, J Fujimoto  Activation of the Caspase Cascade During Stx1-induced Apoptosis in Burkitt's Lymphoma Cells  J Cell Biochem  2001  81 (1), 128-42  PubMed ID: 11180403   DOI: 10.1002/1097-4644(20010401)81:1<128::aid-jcb1029>3.0.co;2-g
9021  N Hasegawa, Y Kimura, T Oda, N Komatsu, T Muramatsu  Isolated Ricin B-chain-mediated Apoptosis in U937 Cells  Biosci Biotechnol Biochem  2000  64 (7), 1422-9  PubMed ID: 10945259   DOI: 10.1271/bbb.64.1422
1899  Bamba H, Ota S, Kato A, Kawamoto C, Fujiwara K.  Prostaglandins up-regulate vascular endothelial growth factor production through distinct pathways in differentiated U937 cells  Biochem Biophys Res Commun  2000  273(2):485-91  PubMed ID: 10873632   DOI: 10.1006/bbrc.2000.2969
11971  Watabe M, Kakeya H, Onose R, Osada H.  Activation of MST/Krs and c-Jun N-terminal kinases by different signaling pathways during cytotrienin A-induced apoptosis  J Biol Chem  2000  275(12):8766-71  PubMed ID: 10722720   DOI: 10.1074/jbc.275.12.8766
17259  Kaneko A, Suzuki S, Hara M, Mori J, Kumagai M, Yajima H, Yamashita K, Kakizawa T, Yamazaki M, Takeda T, Miyamoto T, Ichikawa K, Hashizume K.  1,25-Dihydroxyvitamin D3 suppresses the expression of the VCAM-1 receptor, VLA-4 in human leukemic HL-60 cells  Biochem Biophys Res Commun  1999  255(2):371-6  PubMed ID: 10049715   DOI: 10.1006/bbrc.1999.0186
18031  Imai T, Fujii K, Shiraishi S, Otagiri M.  Alteration of pharmacokinetics and nephrotoxicity of cisplatin by alginates  J Pharm Sci  1997  86(2):244-7  PubMed ID: 9040103   DOI: 10.1021/js9601997
18078  Atsumi G, Murakami M, Tajima M, Shimbara S, Hara N, Kudo I.  The perturbed membrane of cells undergoing apoptosis is susceptible to type II secretory phospholipase A2 to liberate arachidonic acid  Biochim Biophys Acta  1997  1349(1):43-54  PubMed ID: 9421195   DOI: 10.1016/s0005-2760(97)00082-9
3753  Murakami K, Nomiyama H, Miura R, Follens A, Fiten P, Van Coillie E, Van Damme J, Opdenakker G.  Structural and functional analysis of the promoter region of the human MCP-3 gene: transactivation of expression by novel recognition sequences adjacent to the transcription initiation site.  DNA Cell Biol  1997  16(2):173-83  PubMed ID: 9052738   DOI: 10.1089/dna.1997.16.173
17982  Koseki T, Yamato K, Krajewski S, Reed JC, Tsujimoto Y, Nishihara T.  Activin A-induced apoptosis is suppressed by BCL-2  FEBS Lett  1995  376(3):247-50  PubMed ID: 7498552   DOI: 10.1016/0014-5793(95)01290-7
1855  Hashimoto E, Kage K, Ogita T, Nakaoka T, Matsuoka R, Kira Y  Adenosine as an endogenous mediator of hypoxia for induction of vascular endothelial growth factor mRNA in U-937 cells.  Biochem Biophys Res Commun  1994  204:318-24  PubMed ID: 7945378   DOI: 10.1006/bbrc.1994.2462
15581  Kojima N, Saito M, Tsuji S.  Role of cell surface O-linked oligosaccharides in adhesion of HL60 cells to fibronectin: regulation of integrin-dependent cell adhesion by O-linked oligosaccharide elongation  Exp Cell Res  1994  214(2):537-42  PubMed ID: 7925647   DOI: 10.1006/excr.1994.1291
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