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RCB0247 : 10T1/2  update : 2018/07/06
CommentClone 8, Contact-inhibited semi-normal
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC( regarding any kind of for-profit use.
Basic information Depositor Terasima, Toyozo
Originator Reznikoff, Catherine A.
Year of deposit 1988
Another name 10T1/2(clone8)
Animal mouse < Mammals
Strain name C3H
Age at sampling embryo
Tissue embryo
Classification normal
Lifespan infinite
Morphology fibroblast-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives BME (2mM L-Glutamine) + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage cell No 5 x 10^(4) cells/60 mm dish
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP (mouse) OK
Isozyme LD, NP
Chromosome mode 65-81(50) : /75(1),76(1),77(3),78(5),79(12),80(25)/
deposit info
lot info
Reference information Reference 5
User's Publication 96

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2000  Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine.  Taylor, S M, Jones, P A  Cell  1979  17:771-9  PubMed ID: 90553
44  Neoplasms produced from C3H/10T 1/2 cells attached to plastic plates; saturation density, anchorage dependence and serum requirement of in vitro lines correlated with growth aggressiveness in vivo.  Paranjpe M, del Ande Eaton S, Boone, C W  J Cell Physiol  1978  96:63-71  PubMed ID: 659520
2001  The myoD gene family: nodal point during specification of the muscle cell lineage.  Weintraub H, Davis R, Tapscott S, Thayer M, Krause M, Benezra R, Blackwell, T K, Turner D, Rupp R, Hollenberg S, et al.  Science  1991  251:761-6  PubMed ID: 1846704
961  Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.  Reznikoff, C A, Brankow, D W, Heidelberger C  Cancer Res  1973  33:3231-8  PubMed ID: 4357355
962  Radiation-induced transformation of 10T 1/2 mouse cells in the plateau phase: post-irradiation changes and serum dependence.  Terasima T, Yasukawa M, Kimura M  Gann  1981  72:762-8  PubMed ID: 7327374

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User's Publication
2644  Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription  Funato N, Ohyama K, Kuroda T, Nakamura M  J Biol Chem  2002  278:7486-7493  PubMed ID: 12493738
2635  Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis.  Hata K, Nishimura R, Ikeda F, Yamashita K, Matsubara T, Nokubi T, Yoneda T  Mol Biol Cell  2003  14:545-55  PubMed ID: 12589053
2874  The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.  Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung UI  Biochem Biophys Res Commun  2005  333:1300-8  PubMed ID: 15979579
2915  Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling.  Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A  J Biol Chem  2005  280:15842-8  PubMed ID: 15695512
2936  Odd-skipped related 2 splicing variants show opposite transcriptional activity.  Kawai S, Kato T, Inaba H, Okahashi N, Amano A  Biochem Biophys Res Commun  2005  328:306-11  PubMed ID: 15670784
1329  The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2.  Katagiri T, Yamaguchi A, Ikeda T, Yoshiki S, Wozney, J M, Rosen V, Wang, E A, Tanaka H, Omura S, Suda T  Biochem Biophys Res Commun  1990  172:295-9  PubMed ID: 1699539
2480  Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development.  Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S  J Biol Chem  2001  276:3628-34  PubMed ID: 11071891
2893  Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation.  Ichida, Fumitaka, Nishimura, Riko, Hata, Kenji, Matsubara, Takuma, Ikeda, Fumiyo, Hisada, Kunihiro, Yatani, Hirofumi, Cao, Xu, Komori, Toshihisa, Yamaguchi, Akira, Yoneda, Toshiyuki  J Biol Chem  2004  279:34015-22  PubMed ID: 15175325
2899  Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling.  Fujita, Takashi, Azuma, Yasutaka, Fukuyama, Ryo, Hattori, Yuji, Yoshida, Carolina, Koida, Masao, Ogita, Kiyokazu, Komori, Toshihisa  J Cell Biol  2004  166:85-95  PubMed ID: 15226309
3343  Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs.  Ishihara, Keiichi, Yamagishi, Nobuyuki, Hatayama, Takumi  Eur J Biochem  2004  271:4552-8  PubMed ID: 15560796
3183  A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes.  Hata, Kenji, Nishimura, Riko, Ueda, Mio, Ikeda, Fumiyo, Matsubara, Takuma, Ichida, Fumitaka, Hisada, Kunihiro, Nokubi, Takashi, Yamaguchi, Akira, Yoneda, Toshiyuki  Mol Cell Biol  2005  25:1971-9  PubMed ID: 15713650
7113  Influence of polymer molecular weight on the in vitro cytotoxicity of poly (N-isopropylacrylamide).  Mellati A, Valizadeh Kiamahalleh M, Dai S, Bi J, Jin B, Zhang H.  Mater Sci Eng C Mater Biol Appl  2015  59:509-513  PubMed ID: 26652402
7378  Cell-selective encapsulation in hydrogel sheaths via biospecific identification and biochemical cross-linking.  Sakai S, Liu Y, Sengoku M, Taya M.  Biomaterials  2015  53:494-501  PubMed ID: 25890746
7632  Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes.  Kawato Y, Hirao M, Ebina K, Tamai N, Shi K, Hashimoto J, Yoshikawa H, Myoui A.  Biochem. Biophys. Res. Commun.  2011  416:205-10  PubMed ID: 22093831
7688  The effect of valproic Acid on mesenchymal pluripotent cell proliferation and differentiation in extracellular matrices.  Hatakeyama Y, Hatakeyama J, Takahashi A, Oka K, Tsuruga E, Inai T, Sawa Y.  Drug Target Insights  2011  5:1-9  PubMed ID: 21904447
7804  Characterization of stress sensitivity and chaperone activity of Hsp105 in mammalian cells.  Yamagishi N, Yokota M, Yasuda K, Saito Y, Nagata K, Hatayama T.  Biochem. Biophys. Res. Commun.  2011  409:90-5  PubMed ID: 21557931
7855  Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells.  Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M.  J. Biol. Chem.  2011  286:19138-48  PubMed ID: 21471203
8035  CD271/p75(NTR) inhibits the differentiation of mesenchymal stem cells into osteogenic, adipogenic, chondrogenic, and myogenic lineages.  Mikami Y, Ishii Y, Watanabe N, Shirakawa T, Suzuki S, Irie S, Isokawa K, Honda MJ.  Stem Cells Dev.  2010  20:901-13  PubMed ID: 21142793
8153  Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells.  Takarada-Iemata M, Takarada T, Nakamura Y, Nakatani E, Hori O, Yoneda Y.  J. Cell. Physiol.  2010  226:652-65  PubMed ID: 20717926
8179  Odd-skipped related 2 regulates genes related to proliferation and development.  Kawai S, Abiko Y, Amano A.  Biochem. Biophys. Res. Commun.  2010  398:184-90  PubMed ID: 20599744
8272  Odd-skipped related 2 is epigenetically regulated in cellular quiescence.  Kawai S, Amano A.  Biochem. Biophys. Res. Commun.  2010  396:831-6  PubMed ID: 20450884
8407  Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells.  Mikami Y, Asano M, Honda MJ, Takagi M.  J. Cell. Physiol.  2009  223:123-33  PubMed ID: 20039267
8562  Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation.  Yuasa K, Masuda T, Yoshikawa C, Nagahama M, Matsuda Y, Tsuji A.  J. Biochem.  2009  146:407-15  PubMed ID: 19520771
8595  Osteoinduction by microbubble-enhanced transcutaneous sonoporation of human bone morphogenetic protein-2.  Osawa K, Okubo Y, Nakao K, Koyama N, Bessho K.  J Gene Med  2009  11:633-41  PubMed ID: 19396932
8725  Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells.  Takahata Y, Takarada T, Iemata M, Yamamoto T, Nakamura Y, Kodama A, Yoneda Y.  J. Cell. Physiol.  2008  218:268-75  PubMed ID: 18814142
8727  Odd-skipped related 1 gene expression is regulated by Runx2 and Ikzf1 transcription factors.  Yamauchi M, Kawai S, Kato T, Ooshima T, Amano A.  Gene  2008  426:81-90  PubMed ID: 18804520
8803  Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation.  Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A.  J. Bone Miner. Res.  2007  22:1362-72  PubMed ID: 17547533
9730  Poly(N-isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering.  Mellati A, Kiamahalleh MV, Madani SH, Dai S, Bi J, Jin B, Zhang H.  J Biomed Mater Res A  2016  104:2764-74  PubMed ID: 27325374
9773  Microengineered 3D cell-laden thermoresponsive hydrogels for mimicking cell morphology and orientation in cartilage tissue engineering.  Mellati A, Fan CM, Tamayol A, Annabi N, Dai S, Bi J, Jin B, Xian C, Khademhosseini A, Zhang H.  Biotechnol. Bioeng.  2017  114:217-231  PubMed ID: 27477393
9786  Anchoring PEG-oleate to cell membranes stimulates reactive oxygen species production.  Sakai S, Nomura K, Mochizuki K, Taya M.  Colloids Surf B Biointerfaces  2016  147:336-342  PubMed ID: 27544656
10343  Fabrication of single and bundled filament-like tissues using biodegradable hyaluronic acid-based hollow hydrogel fibers.  Khanmohammadi M, Sakai S, Taya M.  Int. J. Biol. Macromol.  2017  104:204-212  PubMed ID: 28596006
11004  Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a MicroPatterned Gelatin Matrix    International Journal of Theoretical and Applied Nanotechnology  2017  5:20-26 
11014  Versatility of hydrogelation by dual-enzymatic reactions with oxidases and peroxidase    Biochemical Engineering Journal  2018  131, 1-8 
11047  Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro    Cancer Translational Medicine  2018  4, 9-16 
11132  Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex?Vivo Production.  Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K.  Cell  2018  174(3):636-648  PubMed ID: 30017246
11182  Peroxidase-catalyzed microextrusion bioprinting of cell-laden hydrogel constructs in vaporized ppm-level hydrogen peroxide.  Sakai S, Mochizuki K, Qu Y, Mail M, Nakahata M, Taya M.  Biofabrication  2018  10(4):045007  PubMed ID: 30137024
11138  SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.  Nat Commun  2018  9(1):2833  PubMed ID: 30026585
11367  The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.  Ishijima Y, Ohmori S, Uneme A, Aoki Y, Kobori M, Ohida T, Arai M, Hosaka M, Ohneda K.  Mol. Cell. Endocrinol.  2019    PubMed ID: 30615908
11397  Horseradish peroxidase-catalyzed hydrogelation consuming enzyme-produced hydrogen peroxide in the presence of reducing sugars.  Gantumur E, Sakai S, Nakahata M, Taya M.  Soft Matter  2019    PubMed ID: 30672948
4059  Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.  Yoshida K, Teramachi J, Uchibe K, Ikegame M, Qiu L, Yang D, Okamura H.  Mol. Cell. Endocrinol.  2018  470:251-258  PubMed ID: 29128580
4109  Micro patterning of hydroxyapatite by soft lithography on hydrogels for selective osteoconduction.  Kiyama R, Nonoyama T, Wada S, Semba S, Kitamura N, Nakajima T, Kurokawa T, Yasuda K, Tanaka S, Gong JP.  Acta Biomater  2018    PubMed ID: 30292679
4110  Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations.  Takei H, Edahiro Y, Mano S, Masubuchi N, Mizukami Y, Imai M, Morishita S, Misawa K, Ochiai T, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.  Br. J. Haematol.  2018    PubMed ID: 29741776
3584  Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation.  Muramatsu S, Wakabayashi M, Ohno T, Amano K, Ooishi R, Sugahara T, Shiojiri S, Tashiro K, Suzuki Y, Nishimura R, Kuhara S, Sugano S, Yoneda T, Matsuda A.  J Biol Chem  2007  282(44):32158-67  PubMed ID: 17804410
3926  Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact.  Jimi E, Nakamura I, Amano H, Taguchi Y, Tsurukai T, Tamura M, Takahashi N, Suda T.  Endocrinology.  1996  137(8):2187-90  PubMed ID: 8754795
3808  Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation.  Kinto N, Iwamoto M, Enomoto-Iwamoto M, Noji S, Ohuchi H, Yoshioka H, Kataoka H, Wada Y, Yuhao G, Takahashi HE, Yoshiki S, Yamaguchi A.  FEBS Lett  1997  404(2-3):319-23  PubMed ID: 9119087
3937  Cloning and characterization of the 5'-flanking region of the mouse diastrophic dysplasia sulfate transporter gene.  Kobayashi T, Sugimoto T, Saijoh K, Fujii M, Chihara K.  Biochem Biophys Res Commun  1997  238(3):738-43  PubMed ID: 9325159
3921  Identification of an enhancer sequence in 5'-flanking region of 1A exon of mouse liver/bone/kidney-type alkaline phosphatase gene.  Kobayashi T, Sugimoto T, Kanzawa M, Chihara K.  Biochem Mol Biol Int  1998  44(4):683-91  PubMed ID: 9584982
3922  1,25-Dihydroxyvitamin D3 upregulates natriuretic peptide receptor-C expression in mouse osteoblasts.  Yanaka N, Akatsuka H, Kawai E, Omori K.  Am J Physiol  1998  275(6):E965-73  PubMed ID: 9843738
3968  Identification of DERMO-1 as a member of helix-loop-helix type transcription factors expressed in osteoblastic cells.  Tamura M, Noda M.  J Cell Biochem  1999  72(2):167-76  PubMed ID: 10022499
3969  Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5.  Akiyama H1, Hiraki Y, Noda M, Shigeno C, Ito H, Nakamura T.  J Biol Chem  1999.  274(45):32192-7  PubMed ID: 10542256
3989  The Role of Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) in the Differentiation of Osteoblasts and Chondrocytes  Yoshimasa FUJIMAKI  The Showa University Journal of Medical Sciences  2000  12:39-49 
3997  Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation.  Enomoto-Iwamoto M, Nakamura T, Aikawa T, Higuchi Y, Yuasa T, Yamaguchi A, Nohno T, Noji S, Matsuya T, Kurisu K, Koyama E, Pacifici M, Iwamoto M.  J Bone Miner Res  2000  15(9):1659-68  PubMed ID: 10976986
3999  A chemical probe that labels human pluripotent stem cells.  Hirata N et al  Cell Rep  2014  6(6):1165-1174  PubMed ID: 24613351
5990  Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells.  Kikuchi Y, Kume A, Urabe M, Mizukami H, Suzuki T, Ozaki K, Nagai T, Ozawa K.  J Stem Cells Regen Med  2011  7(2):61-8  PubMed ID: 24693172
5991  In vitro generation of megakaryocytes and platelets from human embryonic stem cells and induced pluripotent stem cells.  Takayama N, Eto K.  Methods Mol Biol  2012  788:205-17  PubMed ID: 22130710
6001  Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein (BMP) signaling.  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, Hoshi K.  J Cell Physiol  2013  228(1):163-71  PubMed ID: 22585661
6012  Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4.  Zhao WH1, Hu ZQ.  Cytokine  2012  58(2):267-73  PubMed ID: 22370606
6028  Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells.  Kawamura F et al  Sci Rep  2017  7(1):1659  PubMed ID: 28490810
6073  Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes.  Nakagawa Y, Nakamura S, Nakajima M, Endo H, Dohda T, Takayama N, Nakauchi H, Arai F, Fukuda T, Eto K.  Exp Hematol  2013  41(8):742-8  PubMed ID: 23618622
6131  The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.  Stem Cells  2009  27(5):1120-9  PubMed ID: 19415782
6157  Reversible integration of the dominant negative retinoid receptor gene for ex vivo expansion of hematopoietic stem/progenitor cells.  Muramatsu M, Hanazono Y, Ogasawara Y, Okada T, Mizukami H, Kume A, Mizoguchi H, Ozawa K.  Biochem Biophys Res Commun  2001  285(4):891-6  PubMed ID: 11467834
3546  Modulation of Osteonectin and Osteopontin Expression during Fracture Healing of Mouse Bone Tissue  Hideyoshi Kashimoto, Riko Kitazawa, Sakan Maeda, Kosaku Mizuno, Sohei Kitazawa  ACTA HISTOCHEMICA ET CYTOCHEMICA  1998  31:501-508 
3540  Characterization of a bone morphogenetic protein-responsive Smad-binding element.  Kusanagi K, Inoue H, Ishidou Y, Mishima HK, Kawabata M, Miyazono K.  Mol Biol Cell  2000  11(2):555-65  PubMed ID: 10679014
3542  Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.  Ito H, Akiyama H, Iguchi H, Iyama K, Miyamoto M, Ohsawa K, Nakamura T.  J Biol Chem  2001  276(26):24023-9  PubMed ID: 11292829
3560  New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.  Fujita T, Meguro T, Fukuyama R, Nakamuta H, Koida M.  J Biol Chem  2002  277(25):22191-200  PubMed ID: 11956184
4944  Anti-membrane-bound transferrin-like protein antibodies induce cell-shape change and chondrocyte differentiation in the presence or absence of concanavalin A.  Oda R, Suardita K, Fujimoto K, Pan H, Yan W, Shimazu A, Shintani H, Kato Y.  J Cell Sci  2003  116(Pt 10):2029-38  PubMed ID: 12679380
6519  Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice.  Hata K, Nishimura R, Muramatsu S, Matsuda A, Matsubara T, Amano K, Ikeda F, Harley VR, Yoneda T.  J Clin Invest  2008  118(9):3098-108  PubMed ID: 18677406
6534  Transcriptional regulation of fibrillin-2 gene by E2F family members in chondrocyte differentiation.  Yanagino T, Yuasa K, Nagahama M, Matsuda Y, Tsuji A.  J Cell Biochem  2009  106(4):580-8  PubMed ID: 19142862
11582  TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN.  Numaga-Tomita T, Shimauchi T, Oda S, Tanaka T, Nishiyama K, Nishimura A, Birnbaumer L, Mori Y, Nishida M.  FASEB J.  2019    PubMed ID: 31162976
11589  Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.  Aoki H, Yamashita M, Hashita T, Nakayama M, Yagi M, Iwao T, Matsunaga T.  Biochem. Biophys. Res. Commun.  2019  515(4):672-678  PubMed ID: 31178142
11681  Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells  Hiroe Morimoto-Ito, Masako Mizuno-Kamiya, Naoki Umemura, Yoshinori Inagaki, Eiji Takayama, Harumi Kawaki, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh  The Open Dentistry Journal  2019  13:221-227 
11738  In Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem Cells.  Iriguchi S, Kaneko S.  Methods Mol. Biol.  2019    PubMed ID: 31396934
11743  Redifferentiation of Adaptive Naïve-Like CTL from T-Cell-Derived iPSC.  Kawai Y, Kaneko S.  Methods Mol. Biol.  2019    PubMed ID: 31396930
11765  The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity.  Abe T, Sato T, Yoda T, Hoshi K.  Regen Ther  2019    PubMed ID: 31489343
11838  Endothelial specific deletion of FOXO1 alters pericyte coverage in the developing retina.  Niimi K, Adachi Y, Ishikawa H, Yamaguchi W, Kubota Y, Inagaki S, Furuyama T.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31601422
4679  The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.  Takigawa Y, Hata K, Muramatsu S, Amano K, Ono K, Wakabayashi M, Matsuda A, Takada K, Nishimura R, Yoneda T.  J Cell Sci  2010  123(Pt 21):3780-8  PubMed ID: 20940257
5318  Basic helix-loop-helix transcription factor Twist1 inhibits transactivator function of master chondrogenic regulator Sox9.  Gu S, Boyer TG, Naski MC.  J Biol Chem.   2012  287(25):21082-92  PubMed ID: 22532563
6554  Impact of medium volume and oxygen concentration in the incubator on pericellular oxygen concentration and differentiation of murine chondrogenic cell culture.  Oze H, Hirao M, Ebina K, Shi K, Kawato Y, Kaneshiro S, Yoshikawa H, Hashimoto J.  In Vitro Cell Dev Biol Anim  2012  48(2):123-30  PubMed ID: 22259015
6578  Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes.  Zanotti S1, Canalis E.  Endocrinology  2013  154(2):762-72  PubMed ID: 23264614
6572  SOX11 contributes to the regulation of GDF5 in joint maintenance.  Kan A, Ikeda T, Fukai A, Nakagawa T, Nakamura K, Chung UI, Kawaguchi H, Tabin CJ.  BMC Dev Biol  2013  13:4  PubMed ID: 23356643
6575  Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes.  Hata K, Takashima R, Amano K, Ono K, Nakanishi M, Yoshida M, Wakabayashi M, Matsuda A, Maeda Y, Suzuki Y, Sugano S, Whitson RH, Nishimura R, Yoneda T.  Nat Commun  2013  4:2850  PubMed ID: 24276541
6647  Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.  Takahata Y, Nakamura E, Hata K, Wakabayashi M, Murakami T, Wakamori K, Yoshikawa H, Matsuda A, Fukui N, Nishimura R.  FASEB J  2019  33(1):619-630  PubMed ID: 30016600
6659  The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/carrier complex on bone repair.  Tamura S, Kataoka H, Matsui Y, Shionoya Y, Ohno K, Michi KI, Takahashi K, Yamaguchi A.  Bone  2001  29(2):169-75  PubMed ID: 11502479
6691  Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2.  Yuasa T, Kataoka H, Kinto N, Iwamoto M, Enomoto-Iwamoto M, Iemura S, Ueno N, Shibata Y, Kurosawa H, Yamaguchi A.  J Cell Physiol  2002  193(2):225-32  PubMed ID: 12385000
6699  FK506 enhanced osteoblastic differentiation in mesenchymal cells.  Tang L, Ebara S, Kawasaki S, Wakabayashi S, Nikaido T, Takaoka K.  Cell Biol Int  2002  26(1):75-84  PubMed ID: 11779223
6703  Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis.  Katagiri T, Imada M, Yanai T, Suda T, Takahashi N, Kamijo R.  Genes Cells  2002  7(9):949-60  PubMed ID: 12296825
5039  Effect of the phosphodiesterase 4 inhibitor, rolipram, on retinoic acid-increased alkaline phosphatase activity in the mouse fibroblastic C3H10T1/2 cell line.  Murata T, Sugatani T, Shimizu K, Manganiello VC, Tagawa T.  Arch Oral Biol  2003  48(1):63-7  PubMed ID: 12615143
6714  Bone morphogenetic protein-2 induces differentiation of multipotent C3H10T1/2 cells into osteoblasts, chondrocytes, and adipocytes in vivo and in vitro.  Date T, Doiguchi Y, Nobuta M, Shindo H.  J Orthop Sci  2004  9(5):503-8  PubMed ID: 15449126
6876  Hepatocyte growth factor contributes to fracture repair by upregulating the expression of BMP receptors.  Imai Y, Terai H, Nomura-Furuwatari C, Mizuno S, Matsumoto K, Nakamura T, Takaoka K.  J Bone Miner Res  2005  20(10):1723-30  PubMed ID: 16160730
6878  Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation.  Yano F, Ohba S, Murahashi Y, Tanaka S, Saito T, Chung UI.  Sci Rep  2019  9(1):7666  PubMed ID: 31113964
6884  In Vitro Differentiation of T Cells: From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.  Iriguchi S, Kaneko S.  Methods Mol Biol  2019  2048:59-70  PubMed ID: 31396929
6907  A method of producing genetically manipulated mouse mammary gland.  Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, Ohashi Y, Mikami H, Yamamoto M, Ihara T, Kumazawa K, Sugihara K, Goshima N, Watanabe S, Semba K.  Breast Cancer Res  2019  21(1):1  PubMed ID: 30611295
6998  Odd-skipped related 2 gene transcription is regulated by CCAAT enhancer-binding protein delta in mesenchymal C3H10T1/2 cells.  Kawai S, Kato T, Sato M, Amano A.  Genes Cells  2006  11(2):163-75  PubMed ID: 16436053
3357  Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.  Hiroyama, Takashi, Miharada, Kenichi, Aoki, Naoko, Fujioka, Tsuyoshi, Sudo, Kazuhiro, Danjo, Inaho, Nagasawa, Toshiro, Nakamura, Yukio  Exp Hematol  2006  34:760-9  PubMed ID: 16728281
3158  Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds.  Nishimura, Haruki, Nishimura, Masahiro, Oda, Ryo, Yamanaka, Katsuyuki, Matsubara, Takehiro, Ozaki, Yoshie, Sekiya, Kensuke, Hamada, Taizo, Kato, Yukio  Exp Cell Res  2004  295:119-27  PubMed ID: 15051495
3159  Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion.  Miharada, Ken-ichi, Hiroyama, Takashi, Sudo, Kazuhiro, Nagasawa, Toshiro, Nakamura, Yukio  FASEB J  2005  19:1881-3  PubMed ID: 16157692

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