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RCB0007 : HeLa  update : 2018/07/06
細胞特性(Comment:英)Just like ATCC CCL 2, HeLa
細胞特性(日)培養細胞の中で最もよく利用されるヒト子宮頸部癌細胞である。多数の亜株があるが、これはGeyのオリジナル株由来である。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)Basically, there is no restriction regarding academic use.
使用条件(日)学術研究における利用につきましては原則として使用制限はありません。
備考(英)
備考(日)
提供申込書類 依頼書C-0001.pdf   同意書(非営利)C-0003.pdf   同意書(営利)C-0003p.pdf  
提供同意書は、使用機関及び使用内容に応じて二種類あります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は別途ご相談(cellbank.brc@riken.jp)を承ります。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Soeda, Eiichi
樹立者 Gey, G. O. et al.
寄託日 1986
動物種 human < Mammals
属名 Homo
種名 sapiens
性別 Female
31 years
採取組織 cervix
病歴 cervical carcinoma
細胞分類 cancer
初代培養日 1952
細胞寿命 infinite
細胞形態 epithelial-like
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 MEM + 10% CS
抗生物質 Free
継代方法 0.25% trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : 1-2 times/week, Medium Renewal : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
個体識別検査 OK
ウィルス(HIV) (-)
アイソザイム検査 LD, NP
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 3件
Reference(日) 4件
利用者成果(英) 118件
利用者成果(日) 0件

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Reference(英)
150  Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium.  Gey,G.O., Coffman,W.D. and Kubicek,M.T.  Cancer Res  1952  12:264-265 
4660  The minimum vitamin requirements of the L and HeLa cells in tissue culture, the production of specific vitamin deficiencies, and their cure.  EAGLE H.  J Exp Med  1955  102(5):595-600  PubMed ID: 3271674
1444  A RAPID METHOD FOR VIABLE CELL TITRATION AND CLONE PRODUCTION WITH HELA CELLS IN TISSUE CULTURE: THE USE OF X-IRRADIATED CELLS TO SUPPLY CONDITIONING FACTORS.  Puck TT1, Marcus PI.  Proc Natl Acad Sci U S A  1955  41(7):432-7  PubMed ID: 16589695

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Reference(日)
1228  バイオテクノロジ-素材としての培養細胞 体細胞遺伝学  花岡文雄  蛋白質 核酸 酵素  1988  33:291-292 
1248  バイオテクノロジ-素材としての培養細胞 細胞周期  花岡文雄  蛋白質 核酸 酵素  1988  33:1331-1331 
1276  バイオテクノロジ-素材としての培養細胞 生化学実験  花岡文雄  蛋白質 核酸 酵素  1988  33:1576-1577 
1714  ヒト子宮頸癌 : HeLa  安光英太郎  生体の科学  1992  43:409 

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利用者成果(英)
3389  Evaluation of the nuclear delivery and intra-nuclear transcription of plasmid DNA condensed with micro (mu) and NLS-micro by cytoplasmic and nuclear microinjection: a comparative study with poly-L-lysine.  Akita, Hidetaka, Tanimoto, Mitsuhide, Masuda, Tomoya, Kogure, Kentaro, Hama, Susumu, Ninomiya, Keiko, Futaki, Shiroh, Harashima, Hideyoshi  J Gene Med  2006  8:198-206  PubMed ID: 16285003
2701  Inhibition of attachment of virions of Norwalk virus to mammalian cells by soluble histone molecules.  Tamura M, Natori K, Kobayashi M, Miyamura T, Takeda N  Arch Virol  2003  148:1659-70  PubMed ID: 14505080
2955  The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor.  Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H  Mol Endocrinol  2005  19:1110-24  PubMed ID: 15677712
2382  Chain length of cationic alpha-helical peptide sufficient for gene delivery into cells.  Niidome T, Takaji K, Urakawa M, Ohmori N, Wada A, Hirayama T, Aoyagi H  Bioconjug Chem  1999  10:773-80  PubMed ID: 10502342
7046  IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact.  Bonneau B, Ando H, Kawaai K, Hirose M, Takahashi-Iwanaga H, Mikoshiba K.  Elife  2016  5:  PubMed ID: 27995898
7048  Five colour variants of bright luminescent protein for real-time multicolour bioimaging.  Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.  Nat Commun  2016  7:13718  PubMed ID: 27966527
7058  Constitutive activation of DIA1 (DIAPH1) via C-terminal truncation causes human sensorineural hearing loss.  Ueyama T, Ninoyu Y, Nishio SY, Miyoshi T, Torii H, Nishimura K, Sugahara K, Sakata H, Thumkeo D, Sakaguchi H, Watanabe N, Usami SI, Saito N, Kitajiri SI.  EMBO Mol Med  2016  8:1310-1324  PubMed ID: 27707755
7060  Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.  Kanda S, Yanagitani K, Yokota Y, Esaki Y, Kohno K.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E5886-E5895  PubMed ID: 27651490
7090  Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.  Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, Kataoka K, Saito T, Chung UI, Ohba S.  Sci Rep  2016  6:18743  PubMed ID: 26728350
7100  Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium.  Bannai H, Niwa F, Sherwood MW, Shrivastava AN, Arizono M, Miyamoto A, Sugiura K, Levi S, Triller A, Mikoshiba K.  Cell Rep  2015  13:2768-80  PubMed ID: 26711343
7154  Rolling Circle Translation of Circular RNA in Living Human Cells.  Abe N, Matsumoto K, Nishihara M, Nakano Y, Shibata A, Maruyama H, Shuto S, Matsuda A, Yoshida M, Ito Y, Abe H.  Sci Rep  2015  5:16435  PubMed ID: 26553571
7339  BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy.  Kobayashi S, Koujin T, Kojidani T, Osakada H, Mori C, Hiraoka Y, Haraguchi T.  Proc. Natl. Acad. Sci. U.S.A.  2015  112:7027-32  PubMed ID: 25991860
7614  Diphosphorylated but not monophosphorylated myosin II regulatory light chain localizes to the midzone without its heavy chain during cytokinesis.  Kondo T, Isoda R, Uchimura T, Sugiyama M, Hamao K, Hosoya H.  Biochem. Biophys. Res. Commun.  2011  417:686-91  PubMed ID: 22166199
7617  β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.  Satow R, Shitashige M, Jigami T, Fukami K, Honda K, Kitabayashi I, Yamada T.  Gastroenterology  2011  142:572-81  PubMed ID: 22155184
7739  Accumulation of p21 proteins at DNA damage sites independent of p53 and core NHEJ factors following irradiation.  Koike M, Yutoku Y, Koike A.  Biochem. Biophys. Res. Commun.  2011  412:39-43  PubMed ID: 21787748
7809  Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51.  Ochiai K, Yoshikawa Y, Yoshimatsu K, Oonuma T, Tomioka Y, Takeda E, Arikawa J, Mominoki K, Omi T, Hashizume K, Morimatsu M.  FEBS Lett.  2011  585:1771-7  PubMed ID: 21601571
7923  Induction of cell-cell connections by using in situ laser lithography on a perfluoroalkyl-coated cultivation platform.  Okano K, Yu D, Matsui A, Maezawa Y, Hosokawa Y, Kira A, Matsubara M, Liau I, Tsubokawa H, Masuhara H.  Chembiochem  2011  12:795-801  PubMed ID: 21341350
7953  Module M1 of zebrafish neuroglobin acts as a structural and functional protein building block for a cell-membrane-penetrating activity.  Watanabe S, Wakasugi K.  PLoS ONE  2011  6:e16808  PubMed ID: 21304818
7983  Enhancement of myosin II/actin turnover at the contractile ring induces slower furrowing in dividing HeLa cells.  Kondo T, Hamao K, Kamijo K, Kimura H, Morita M, Takahashi M, Hosoya H.  Biochem. J.  2011  435:569-76  PubMed ID: 21231914
7995  Photocontrol of cell adhesion on amino-bearing surfaces by reversible conjugation of poly(ethylene glycol) via a photocleavable linker.  Kaneko S, Nakayama H, Yoshino Y, Fushimi D, Yamaguchi K, Horiike Y, Nakanishi J.  Phys Chem Chem Phys  2011  13:4051-9  PubMed ID: 21225032
8341  Separation of viable and nonviable animal cell using dielectrophoretic filter.  Hakoda M, Wakizaka Y, Hirota Y.  Biotechnol. Prog.  2010  26:1061-7  PubMed ID: 20205163
8436  Cytotoxic constituents of propolis from Myanmar and their structure-activity relationship.  Li F, Awale S, Tezuka Y, Kadota S.  Biol. Pharm. Bull.  2009  32:2075-8  PubMed ID: 19952433
8509  Cytotoxic constituents of Soymida febrifuga from Myanmar.  Awale S, Miyamoto T, Linn TZ, Li F, Win NN, Tezuka Y, Esumi H, Kadota S.  J. Nat. Prod.  2009  72:1631-6  PubMed ID: 19689125
8605  Direct evidence for roles of phosphorylated regulatory light chain of myosin II in furrow ingression during cytokinesis in HeLa cells.  Asano S, Hamao K, Hosoya H.  Genes Cells  2009  14:555-68  PubMed ID: 19371382
8606  New function of the proline rich domain in dynamin-2 to negatively regulate its interaction with microtubules in mammalian cells.  Hamao K, Morita M, Hosoya H.  Exp. Cell Res.  2009  315:1336-45  PubMed ID: 19331814
8644  Differential recognition of heat shock elements by members of the heat shock transcription factor family.  Yamamoto N, Takemori Y, Sakurai M, Sugiyama K, Sakurai H.  FEBS J.  2009  276:1962-74  PubMed ID: 19250318
8677  Organic Solvent-Free Fluorescence Confocal Imaging of Living Cells Using Pure Nanocrystal Forms of Fluorescent Dyes  Koichi Baba, Hitoshi Kasai, Akito Masuhara, Hidetoshi Oikawa, and Hachiro Nakanishi  Jpn J Appl Phys.  2009  48:117002-1-117002-4 
8759  Zebrafish neuroglobin is a cell-membrane-penetrating globin.  Watanabe S, Wakasugi K.  Biochemistry  2008  47:5266-70  PubMed ID: 18416560
8791  Human tryptophanyl-tRNA synthetase binds with heme to enhance its aminoacylation activity.  Wakasugi K.  Biochemistry  2007  46:11291-8  PubMed ID: 17877375
8808  The effect of copper concentration on the virulence of pathogenic Vibrio harveyi.  Nakayama T, Nomura N, Matsumura M.  J. Appl. Microbiol.  2007  102:1300-6  PubMed ID: 17448165
8810  Cerasome as an infusible and cell-friendly gene carrier: synthesis of cerasome-forming lipids and transfection using cerasome.  Sasaki Y, Matsui K, Aoyama Y, Kikuchi J.  Nat Protoc  2007  1:1227-34  PubMed ID: 17406406
8856  Myosin II activity is not essential for recruitment of myosin II to the furrow in dividing HeLa cells.  Miyauchi K, Yamamoto Y, Kosaka T, Hosoya H.  Biochem. Biophys. Res. Commun.  2006  350:543-8  PubMed ID: 17022938
8860  Systematic lactose-functionalization of amphiphilic octaamine macrocycle as a gene carrier. Optimization of the charge, size, toxicity, and receptor factors for hepatocyte targeting.  Horiuchi S, Aoyama Y.  J Control Release  2006  116:107-14  PubMed ID: 16905218
8864  Study on the relationship of protease production and luminescence in Vibrio harveyi.  Nakayama T, Nomura N, Matsumura M.  J. Appl. Microbiol.  2006  101:200-5  PubMed ID: 16834607
8880  Comparison of Vibrio harveyi strains isolated from shrimp farms and from culture collection in terms of toxicity and antibiotic resistance.  Nakayama T, Ito E, Nomura N, Nomura N, Matsumura M.  FEMS Microbiol. Lett.  2006  258:194-9  PubMed ID: 16640572
8903  RNAi silencing of exogenous and endogenous reporter genes using a macrocyclic octaamine as a "compact" siRNA carrier. Studies on the nonsilenced residual activity.  Matsui K, Horiuchi S, Sando S, Sera T, Aoyama Y.  Bioconjug. Chem.  2006  17:132-8  PubMed ID: 16417261
9502  PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.  Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.  Cancer Cell  2018  33:355-367.e7  PubMed ID: 29533781
9505  Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand.  Yoshida W, Saikyo H, Nakabayashi K, Yoshioka H, Bay DH, Iida K, Kawai T, Hata K, Ikebukuro K, Nagasawa K, Karube I.  Sci Rep  2018  8:3116  PubMed ID: 29449667
9802  Effects of intronic single nucleotide polymorphisms (iSNPs) of a polysialyltransferase, ST8SIA2 gene found in psychiatric disorders on its gene products.  Hane M, Kitajima K, Sato C.  Biochem. Biophys. Res. Commun.  2016  478:1123-9  PubMed ID: 27565727
9826  Mode of existence and seasonality of midge larvae (Diptera: Chironomidae) in man-made lakes in the Coachella Valley, southern California.  Lothrop BB, Mulla MS.  J. Am. Mosq. Control Assoc.  1995  11:77-85  PubMed ID: 7616195
10018  Dissection of local Ca(2+) signals inside cytosol by ER-targeted Ca(2+) indicator.  Niwa F, Sakuragi S, Kobayashi A, Takagi S, Oda Y, Bannai H, Mikoshiba K.  Biochem. Biophys. Res. Commun.  2016  479:67-73  PubMed ID: 27616195
10024  Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation.  Matsumura K, Nakata S, Taniguchi K, Ii H, Ashihara E, Kageyama S, Kawauchi A, Yoshiki T.  BMC Cancer  2016  16:748  PubMed ID: 27658708
10129  Diacylglycerol kinase ε localizes to subsurface cisterns of cerebellar Purkinje cells.  Hozumi Y, Fujiwara H, Kaneko K, Fujii S, Topham MK, Watanabe M, Goto K.  Cell Tissue Res.  2017  368:441-458  PubMed ID: 28191598
10236  Human-derived fusogenic peptides for the intracellular delivery of proteins.  Sudo K, Niikura K, Iwaki K, Kohyama S, Fujiwara K, Doi N.  J Control Release  2017  255:1-11  PubMed ID: 28385674
10475  Condensin II plays an essential role in reversible assembly of mitotic chromosomes in situ.  Ono T, Sakamoto C, Nakao M, Saitoh N, Hirano T.  Mol. Biol. Cell  2017  28:2875-2886  PubMed ID: 28835373
10628  FAD104, a regulator of adipogenesis, is a novel suppressor of TGF-β-mediated EMT in cervical cancer cells.  Goto M, Osada S, Imagawa M, Nishizuka M.  Sci Rep  2017  7:16365  PubMed ID: 29180690
10629  Arctigenin induces the apoptosis of primary effusion lymphoma cells under conditions of glucose deprivation.  Baba Y, Shigemi Z, Hara N, Moriguchi M, Ikeda M, Watanabe T, Fujimuro M.  Int. J. Oncol.  2018  52:505-517  PubMed ID: 29207179
10637  An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.  Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.  BMC Nephrol  2017  18:353  PubMed ID: 29202719
10807  Super-long single-molecule tracking reveals dynamic-anchorage-induced integrin function.  Tsunoyama TA, Watanabe Y, Goto J, Naito K, Kasai RS, Suzuki KGN, Fujiwara TK, Kusumi A.  Nat. Chem. Biol.  2018  14:497-506  PubMed ID: 29610485
10812  Laser-induced surface deformation microscope for the study of the dynamic viscoelasticity of plasma membrane in a living cell.  Morisaku T, Yui H.  Analyst  2018  143:2397-2404  PubMed ID: 29700531
10913  Clinical potential of DAC-70 sol    Integr Mol Med  2016  3: 645-648 
10924  Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin    RSC Adv  2017  7, 2392-2402 
10945  Development of a Cartridge-type Cell Culture Device Combined with Poly(N-isopropylacrylamide) Coated Substrates    IEEJ Transactions on Sensors and Micromachines  2017  137, 78-83 
11011  Pick-and-Place Operation of Single Cell Using Optical and Electrical Measurements for Robust Manipulation  Nagai M, Kato K, Oohara K, Shibata T.  Micromachines (Basel)  2017  8(12). pii: E350  PubMed ID: 30400543
11117  Construction of Anti-HER2 Recombinants as Targeting Modules for a Drug-delivery System Against HER2-positive Cells.  Tang Q, Onitsuka M, Tabata A, Tomoyasu T, Nagamune H.  Anticancer Res.  2018  38(7):4319-4325  PubMed ID: 29970568
11158  Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting.  Matsumoto S, Caliskan N, Rodnina MV, Murata A, Nakatani K.  Nucleic Acids Res.  2018  46(16):8079-8089  PubMed ID: 30085309
11494  Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport.  Shima T, Morikawa M, Kaneshiro J, Kambara T, Kamimura S, Yagi T, Iwamoto H, Uemura S, Shigematsu H, Shirouzu M, Ichimura T, Watanabe TM, Nitta R, Okada Y, Hirokawa N.  J. Cell Biol.  2018  217(12):4164-4183  PubMed ID: 30297389
11444  Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers.  Mitsuhashi H, Homma S, Beermann ML, Ishimaru S, Takeda H, Yu BK, Liu K, Duraiswamy S, Boyce FM, Miller JB.  Sci Rep  2019    PubMed ID: 30783185
11492  Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators.  Bannai H, Hirose M, Niwa F, Mikoshiba K.  J Vis Exp  2019    PubMed ID: 30958464
4056  tLyP-1-conjugated Au-nanorod@SiO(2) core-shell nanoparticles for tumor-targeted drug delivery and photothermal therapy.  Xu B, Ju Y, Cui Y, Song G, Iwase Y, Hosoi A, Morita Y.  Langmuir  2014  30:7789-97  PubMed ID: 24921672
4058  Initial Cell Adhesion onto a Phospholipid Polymer Brush Surface Modified with a Terminal Cell Adhesion Peptide.  Inoue Y, Onodera Y, Ishihara K.  ACS Appl Mater Interfaces  2018  10:15250-15257  PubMed ID: 29652126
4087  A protein-coupled fluorescent probe for organelle-specific imaging of Na+  Ryo Taguchia, Takuya Teraia, Tasuku Uenoa, Toru Komatsua, Kenjiro Hanaokaa, Yasuteru Urano  Sensors and Actuators B: Chemical   2018  265, 575-581 
4089  Quantitative Analysis of Cargo Density in Single-extracellular Vesicles by Imaging   Taketoshi Kajimoto, Shun-ichi Nakamura   bio-protocol  2018  8 
4205  β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.  Shintani Y, Hayata-Takano A, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H.  PLoS ONE  2018    PubMed ID: 29734363
4206  Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4-Positive Cancer Cell Population.  Miyamoto T, Mizuno N, Kosaka M, Fujitani Y, Ohno E, Ohtsuka A.  Stem Cells  2018    PubMed ID: 29770522
4207  2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) Disrupts Carbohydrate Metabolism of HeLa Cells by Adduct Formation with Intracellular Free Sulfhydryl-Groups, and Induces ATP Depletion and Necrosis.  Takahashi T, Mine Y, Okamoto T.  Biol. Pharm. Bull.  2018    PubMed ID: 30504682
4208  Effects of mismatches distant from the target position on gene correction with a 5'-tailed duplex.  Suzuki T, Yanai Y, Nishigaki N, Nakatsu Y, Tsuzuki T, Kamiya H.  J. Biosci. Bioeng.  2018    PubMed ID: 29361419
4210  Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.  Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Nakamura Y, Chuang VTG, Kinoshita R, Nishida K, Tanaka R, Enoki Y, Ishima Y, Kuniyasu A, Kobashigawa Y, Morioka H, Futaki S, Otagiri M, Maruyama T.  J Control Release  2018    PubMed ID: 29530390
4478  A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.  Omachi K, Kamura M, Teramoto K, Kojima H, Yokota T, Kaseda S, Kuwazuru J, Fukuda R, Koyama K, Matsuyama S, Motomura K, Shuto T, Suico MA, Kai H.  Cell Chem Biol  2018  25(5):634-643.e4  PubMed ID: 29526710
4479  Intracellular reduction of coenzyme Q homologues with a short isoprenoid side chain induces apoptosis of HeLa cells.  Takahashi T, Mine Y, Okamoto T.  J. Biochem.  2018  163(4):329-339  PubMed ID: 29319808
4480  Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3.  Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, Tagaya M.  J. Lipid Res.  2018  59(5):805-819  PubMed ID: 29549094
4481  Michellamines A6 and A7, and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese Ancistrocladus liana and their antiausterity activities against pancreatic cancer cells  Blaise Kimbadi Lombe, Doris Feineis, Virima Mudogo, Reto Brun, Suresh Awale and Gerhard Bringmann  RSC Adv  2018  8:5243 
4530  Dual temperature- and pH-responsive polymeric micelle for selective and efficient two-step doxorubicin delivery  Yuki Hiruta, ORCID logo, Yuki Kanda, Naoya Katsuyama and Hideko Kanazawa  RSC Adv.  2017  7, 29540-29549 
5344  Elasticity and Topography-Controlled Collagen Hydrogels Mimicking Native Cellular Milieus  Tomoko Gowa Oyama, View ORCID ProfileKotaro Oyama, Atsushi Kimura, Fumiya Yoshida, Ryo Ishida, Masashi Yamazaki, Hiromi Miyoshi, View ORCID ProfileMitsumasa Taguchi  bioRxiv  2019   
5357  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.  Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.  Mol Cell  2019  76(5):797-810  PubMed ID: 31606272
5372  Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.  Nakajima Y, Kanno T, Nagaya T, Kuribayashi K, Nakano T, Gotoh A, Nishizaki T.  Cell Physiol Biochem  2015  35(1):51-60  PubMed ID: 25547995
5401  Ligand-independent activation of the glucocorticoid receptor by ursodeoxycholic acid. Repression of IFN-gamma-induced MHC class II gene expression via a glucocorticoid receptor-dependent pathway.  Tanaka H, Makino Y, Miura T, Hirano F, Okamoto K, Komura K, Sato Y, Makino I.  J Immunol  1996  156(4):1601-8  PubMed ID: 8568266
2377  Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action.  Morishima N.  Genes Cells  1999  4(7):401-14  PubMed ID: 10469173
2648  Stability of a recombinant adenoviral vector: optimization of conditions for storage, transport and delivery.  Ugai H, Watanabe S, Suzuki E, Tsutsui-Nakata H, Yokoyama KK, Murata T.  Jpn J Cancer Res  2002  93(5):598-603  PubMed ID: 12036457
2702  Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins.  Futaki S, Niwa M, Nakase I, Tadokoro A, Zhang Y, Nagaoka M, Wakako N, Sugiura Y.  Bioconjug Chem  2004  15(3):475-81  PubMed ID: 15149174
2844  Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells.  Mise-Omata S, Obata Y, Iwase S, Mise N, Doi TS.  Biochem Biophys Res Commun  2005  328(4):1034-42  PubMed ID: 15707982
2861  A fast, simple method for screening radiation susceptibility genes by RNA interference.  Tsuji AB, Sudo H, Sugyo A, Otsuki M, Miyagishi M, Taira K, Imai T, Harada YN.  Biochem Biophys Res Commun  2005  333(4):1370-7  PubMed ID: 15979584
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