CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [HPS0002 : 253G1]

3673 Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N, Yamanaka S. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008 26(1):101-6 PubMed ID: 18059259 DOI: 10.1038/nbt1374

Top

User's Publication

21544 Ueki M, Suzuki T, Kato Y. Large-scale cultivation of human iPS cells in bioreactor with reciprocal mixing. J Biosci Bioeng 2024 PubMed ID: 38185598 DOI: 10.1016/j.jbiosc.2023.12.008

21546 Kuroda T, Yasuda S, Matsuyama S, Miura T, Sawada R, Matsuyama A, Yamamoto Y, Morioka MS, Kawaji H, Kasukawa T, Itoh M, Akutsu H, Kawai J, Sato Y. ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons. Sci Rep 2024 14(1):690 PubMed ID: 38184695 DOI: 10.1038/s41598-023-51082-4

21601 Kitano M, Hayashi Y, Ohnishi H, Okuyama H, Yoshimatsu M, Mizuno K, Kuwata F, Tada T, Kishimoto Y, Morita S, Omori K. Changes in the Proportion of Each Cell Type After hiPSC-Derived Airway Epithelia Transplantation. Cell Transplant 2024 33:9636897241228026 PubMed ID: 38372247 DOI: 10.1177/09636897241228026

21727 Hideaki Fujita, Takayuki Haruki, Kazuhiro Sudo, Yumiko Koga, Yukio Nakamura, Kuniya Abe, Yasuhiko Yoshida, Keiichi Koizumi, Tomonobu M Watanabe Yuragi biomarker concept for evaluating human induced pluripotent stem cells using heterogeneity-based Raman finger-printing Biophysics and Physicobiology 2024 e211016 DOI: 10.2142/biophysico.bppb-v21.s016

21781 Kitano M, Ohnishi H, Makino A, Miyamoto T, Hayashi Y, Mizuno K, Kaba S, Kawai Y, Kojima T, Kishimoto Y, Yamamoto N, Tomonaga K, Omori K. An infection model for SARS-CoV-2 using rat transplanted with hiPSC-airway epithelial cells. Tissue Eng Part A 2024 PubMed ID: 38832872 DOI: 10.1089/ten.TEA.2024.0016

22197 Nakai-Futatsugi Y, Jin J, Ogawa T, Sakai N, Maeda A, Hironaka KI, Fukuda M, Danno H, Tanaka Y, Hori S, Shiroguchi K, Takahashi M. Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile Elife 2024 12:RP92510 PubMed ID: 38722314 DOI: 10.7554/eLife.92510

22198 Kumar M, Chinnathambi S, Bakhori N, Abu N, Etezadi F, Thangavel V, Packwood D, Sivaniah E, Pandian GN. Biomass-derived carbon dots as fluorescent quantum probes to visualize and modulate inflammation Sci Rep 2024 14(1):12665 PubMed ID: 82056 DOI: 10.1038/s41598-024-62901-7

22206 Inomata Y, Kawatani N, Yamashita H, Hattori F. Lgr6-expressing functional nail stem-like cells differentiated from human-induced pluripotent stem cells PLoS One 2024 19(5):e0303260 PubMed ID: 38743670 DOI: 10.1371/journal.pone.0303260

22207 Zhang J, Li J, Qu X, Liu Y, Sun L, Harada A, Hua Y, Sougawa N, Tabata A, Liu L, Miyagawa S. Development of composite functional tissue sheets using hiPSC-CMs and hADSCs to improve the cardiac function after myocardial infarction Bioact Mater 2024 37:533-548 PubMed ID: 38689657 DOI: 10.1016/j.bioactmat.2024.03.028

22208 Li J, Hua Y, Liu Y, Qu X, Zhang J, Ishida M, Yoshida N, Tabata A, Miyoshi H, Shiba M, Higo S, Sougawa N, Takeda M, Kawamura T, Matsuura R, Okuzaki D, Toyofuku T, Sawa Y, Liu L, Miyagawa S. Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment iScience 2024 27(2):108992 PubMed ID: 38333703 DOI: 10.1016/j.isci.2024.108992

17876 Fujita H, Kaneshiro J, Takeda M, Sasaki K, Yamamoto R, Umetsu D, Kuranaga E, Higo S, Kondo T, Asano Y, Sakata Y, Miyagawa S, Watanabe TM. Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation Life Sci Alliance 2023 6(7):e202302070 PubMed ID: 37236659 DOI: 10.26508/lsa.202302070

21125 Togo H, Terada K, Ujitsugu A, Hirose Y, Takeuchi H, Kusunoki M. Fabrication Scaffold with High Dimensional Control for Spheroids with Undifferentiated iPS Cell Properties. Cells 2023 12(2) PubMed ID: 36672213 DOI: 10.3390/cells12020278

21160 Yue F, Era T, Yamaguchi T, Kosho T. Pathophysiological Investigation of Skeletal Deformities of Musculocontractural Ehlers-Danlos Syndrome Using Induced Pluripotent Stem Cells. Genes (Basel) 2023 14(3) PubMed ID: 36981001 DOI: 10.3390/genes14030730

21340 Hanafusa Y, Shiraishi A, Hattori F. Machine learning discriminates P2X7-mediated intracellular calcium sparks in human-induced pluripotent stem cell-derived neural stem cells. Sci Rep 2023 13(1):12673 PubMed ID: 37542080 DOI: 10.1038/s41598-023-39846-4

21395 Tanaka Y, Kadota S, Zhao J, Kobayashi H, Okano S, Izumi M, Honda Y, Ichimura H, Shiba N, Uemura T, Wada Y, Chuma S, Nakada T, Tohyama S, Fukuda K, Yamada M, Seto T, Kuwahara K, Shiba Y. Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin. Stem Cell Res Ther 2023 14(1):240 PubMed ID: 37679796 DOI: 10.1186/s13287-023-03468-4

21414 Abu N, Chinnathambi S, Kumar M, Etezadi F, Bakhori NM, Zubir ZA, Md Salleh SN, Shueb RH, Karthikeyan S, Thangavel V, Abdullah J, Pandian GN. Development of biomass waste-based carbon quantum dots and their potential application as non-toxic bioimaging agents. RSC Adv 2023 13(40):28230-28249 PubMed ID: 37753403 DOI: 10.1039/d3ra05840a

21418 Kitada Y, Ohnishi H, Yamamoto N, Kuwata F, Kitano M, Mizuno K, Omori K. Transplantation of iPSC-derived airway epithelia with a collagen scaffold into the nasal cavity. Tissue Eng Part C Methods 2023 PubMed ID: 37756360 DOI: 10.1089/ten.TEC.2023.0074

21447 Hashida A, Nakazato T, Uemura T, Liu L, Miyagawa S, Sawa Y, Kino-Oka M. Effect of morphological change on the maturation of human induced pluripotent stem cell-derived cardiac tissue in rotating flow culture. Regen Ther 2023 24:479-488 PubMed ID: 37767182 DOI: 10.1016/j.reth.2023.09.002

21470 Hayashi Y, Ohnishi H, Kitano M, Kishimoto Y, Takezawa T, Okuyama H, Yoshimatsu M, Kuwata F, Tada T, Mizuno K, Omori K. Comparative study of immunodeficient rat strains in engraftment of hiPSC-derived airway epithelia. Tissue Eng Part A 2023 PubMed ID: 37950719 DOI: 10.1089/ten.TEA.2023.0214

22210 Lin CY, Ching YY, Wu SF, Lee YK, Fan HC, Su LY, Tsai SY, Chen YC, Shen CI, Su HL. Coating-Free Culture Medium for Establishing and Maintaining Human Induced Pluripotent Stem Cells Cell Transplant 2023 32:9636897231198172 PubMed ID: 37698258 DOI: 10.1177/09636897231198172

17644 Norimasa Miura, Keigo Miura Mutation Reduction of Alopecia-Related Genes in hiPSC Using miR-520d-5p Re:GEN Open 2022 2:136-144 DOI: 10.1089/regen.2022.0042

17707 Kuwata F, Ohnishi H, Yamamoto N, Takezawa T, Yamashita M, Okuyama H, Hayashi Y, Yoshimatsu M, Kitada Y, Tada T, Kobayashi M, Omori K. Transplantation of Human Induced Pluripotent Stem Cell-Derived Airway Cells on Vitrigel Membrane into Rat Nasal Cavity Tissue Eng Part A 2022 28(13-14):586-594 PubMed ID: 34841888 DOI: 10.1089/ten.TEA.2021.0071

13918 Kanda GN, Tsuzuki T, Terada M, Sakai N, Motozawa N, Masuda T, Nishida M, Watanabe CT, Higashi T, Horiguchi SA, Kudo T, Kamei M, Sunagawa GA, Matsukuma K, Sakurada T, Ozawa Y, Takahashi M, Takahashi K, Natsume T. Robotic search for optimal cell culture in regenerative medicine Elife 2022 11:e77007 PubMed ID: 35762203 DOI: 10.1101/2020.11.25.392936

16925 Nakazato T, Kawamura T, Uemura T, Liu L, Li J, Sasai M, Harada A, Ito E, Iseoka H, Toda K, Sawa Y, Miyagawa S. Engineered three-dimensional cardiac tissues maturing in a rotating wall vessel bioreactor remodel diseased hearts in rats with myocardial infarction Stem Cell Reports 2022 17(5):1170-1182 PubMed ID: 35427484 DOI: 10.1016/j.stemcr.2022.03.012

20948 Shirasago Y, Fukazawa H, Nagase S, Shimizu Y, Mizukami T, Wakita T, Suzuki T, Tani H, Kondoh M, Kuroda T, Yasuda S, Sato Y, Hanada K, Fukasawa M. A single mutation in the E2 glycoprotein of hepatitis C virus broadens the claudin specificity for its infection. Sci Rep 2022 12(1):20243 PubMed ID: 36424447 DOI: 10.1038/s41598-022-23824-3

21028 Yamada S, Masuno H, Kagechika H, Tanatani A, Kanda Y. A Novel Lithocholic Acid Derivative Upregulates Detoxification-Related Genes in Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids. Biol Pharm Bull 2022 45(11):1720-1724 PubMed ID: 36328508 DOI: 10.1248/bpb.b22-00492

22205 Shimizu E, Iguchi H, Le MNT, Nakamura Y, Kobayashi D, Arai Y, Takakura K, Benno S, Yoshida N, Tsukahara M, Haneda S, Hasegawa K. A chemically-defined plastic scaffold for the xeno-free production of human pluripotent stem cells Sci Rep 2022 12(1):2516 PubMed ID: 35169157 DOI: 10.1038/s41598-022-06356-8

22212 Ishigaki M, Hitomi H, Ozaki Y, Nishiyama A. Exposing intracellular molecular changes during the differentiation of human-induced pluripotent stem cells into erythropoietin-producing cells using Raman spectroscopy and imaging Sci Rep 2022 12(1):20454 PubMed ID: 36443362 DOI: 10.1038/s41598-022-24725-1

22213 Hua Y, Yoshimochi K, Li J, Takekita K, Shimotsuma M, Li L, Qu X, Zhang J, Sawa Y, Liu L, Miyagawa S. Development and evaluation of a novel xeno-free culture medium for human-induced pluripotent stem cells Stem Cell Res Ther 2022 13(1):223 PubMed ID: 35658933 DOI: 10.1186/s13287-022-02879-z

22214 Kametani Y, Tanaka S, Wada Y, Suzuki S, Umeda A, Nishinaka K, Okada Y, Maeda M, Miyagawa S, Sawa Y, Obana M, Fujio Y. Yes-associated protein activation potentiates glycogen synthase kinase-3 inhibitor-induced proliferation of neonatal cardiomyocytes and iPS cell-derived cardiomyocytes J Cell Physiol 2022 237(5):2539-2549 PubMed ID: 35312066 DOI: 10.1002/jcp.30724

19491 Takeda M, Miyagawa S, Ito E, Harada A, Mochizuki-Oda N, Matsusaki M, Akashi M, Sawa Y. Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types Sci Rep 2021 11(1):5654 PubMed ID: 33707655 DOI: 10.1038/s41598-021-85261-y

12690 Yoshida K, Uehara O, Kurashige Y, Paudel D, Onishi A, Neopane P, Hiraki D, Morikawa T, Harada F, Takai R, Sato J, Saitoh M, Abiko Y. Direct reprogramming of epithelial cell rests of malassez into mesenchymal-like cells by epigenetic agents Sci Rep 2021 11(1):1852 PubMed ID: 33473142 DOI: 10.1038/s41598-020-79426-4

13203 Uto S, Hikita A, Sakamoto T, Mori D, Yano F, Ohba S, Saito T, Takato T, Hoshi K. Ear Cartilage Reconstruction Combining Induced Pluripotent Stem Cell-Derived Cartilage and Three-Dimensional Shape-Memory Scaffold. Tissue Eng Part A 2021 27(9-10):604-617 PubMed ID: 32883178 DOI: 10.1089/ten.TEA.2020.0106

20011 Chikae S, Kubota A, Nakamura H, Oda A, Yamanaka A, Akagi T, Akashi M. Bioprinting 3D human cardiac tissue chips using the pin type printer "Microscopic painting device" and analysis for cardiotoxicity. Biomed Mater 2021 PubMed ID: 33445157 DOI: 10.1088/1748-605X/abdbde

20102 Murayama MA, Arimitsu N, Shimizu J, Fujiwara N, Takai K, Okada Y, Hirotsu C, Takada E, Suzuki T, Suzuki N. Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation. Exp Anim 2021 PubMed ID: 33828024 DOI: 10.1538/expanim.21-0008

14063 Yokoyama J, Miyagawa S, Akagi T, Akashi M, Sawa Y. Human induced pluripotent stem cell-derived three-dimensional cardiomyocyte tissues ameliorate the rat ischemic myocardium by remodeling the extracellular matrix and cardiac protein phenotype PLoS One 2021 16(3):e0245571 PubMed ID: 33720933 DOI: 10.1371/journal.pone.0245571

20162 Hirai T, Kono K, Sawada R, Kuroda T, Yasuda S, Matsuyama S, Matsuyama A, Koizumi N, Utoguchi N, Mizuguchi H, Sato Y. A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell-derived neural progenitor cells. Sci Rep 2021 11(1)11407 PubMed ID: 34075124 DOI: 10.1038/s41598-021-90928-7

20185 Motosugi N, Okada C, Sugiyama A, Kawasaki T, Kimura M, Shiina T, Umezawa A, Akutsu H, Fukuda A. Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs. Cell Rep 2021 35(10):109222 PubMed ID: 34107248 DOI: 10.1016/j.celrep.2021.109222

20193 Iseoka H, Miyagawa S, Sakai Y, Sawa Y. Cardiac fibrosis models using human induced pluripotent stem cell-derived cardiac tissues allow anti-fibrotic drug screening in vitro. Stem Cell Res 2021 54:102420 PubMed ID: 34126557 DOI: 10.1016/j.scr.2021.102420

20319 Takeda M, Ito E, Minami K, Harada A, Mochizuki-Oda N, Sawa Y, Miyagawa S. Elimination of residual undifferentiated induced pluripotent stem cells (iPSCs) using irradiation for safe clinical applications of iPSC-derived cardiomyocytes. Biochem Biophys Res Commun 2021 574:91-96 PubMed ID: 34450429 DOI: 10.1016/j.bbrc.2021.08.065

20325 Tsuji K, Yamada S, Hirai K, Asakura H, Kanda Y. Development of alveolar and airway cells from human iPS cells: toward SARS-CoV-2 research and drug toxicity testing. J Toxicol Sci 2021 46(9):425-435 PubMed ID: 34470994 DOI: 10.2131/jts.46.425

20329 Tadano K, Miyagawa S, Takeda M, Tsukamoto Y, Kazusa K, Takamatsu K, Akashi M, Sawa Y. Cardiotoxicity assessment using 3D vascularized cardiac tissue consisting of human iPSC-derived cardiomyocytes and fibroblasts. Mol Ther Methods Clin Dev 2021 22:338-349 PubMed ID: 34514026 DOI: 10.1016/j.omtm.2021.05.007

15511 Taku Futenma, Yasunori Akiyama, Sho Tanaka, Masaki Honda, Taku Toriumi Epithelial Cell Differentiation from Human Induced Pluripotent Stem Cells Using a Single-Cell Culture Method Journal of Hard Tissue Biology 2021 30:151-160 DOI: 10.2485/jhtb.30.151

16068 Ota A, Hyon SH, Sumi S, Matsumura K. Gene expression analysis of human induced pluripotent stem cells cryopreserved by vitrification using StemCell Keep Biochem Biophys Rep 2021 28:101172 PubMed ID: 34825070 DOI: 10.1016/j.bbrep.2021.101172

19490 Tsujimura T, Takase O, Yoshikawa M, Sano E, Hayashi M, Hoshi K, Takato T, Toyoda A, Okano H, Hishikawa K. Controlling gene activation by enhancers through a drug-inducible topological insulator Elife 2020 9:e47980. PubMed ID: 32369019 DOI: 10.7554/eLife.47980

4117 Csobonyeiova M, Polak S, Danisovic L. Generation of Pancreatic β-cells From iPSCs and their Potential for Type 1 Diabetes Mellitus Replacement Therapy and Modelling. Exp. Clin. Endocrinol. Diabetes 2020 PubMed ID: 30114722 DOI: 10.1055/a-0661-5873

11778 Tateno H, Hiemori K, Minoshima F, Kiyoi K, Matoba K, Katayama J, Kumada Y. Oriented immobilization of rBC2LCN lectin for highly sensitive detection of human pluripotent stem cells using cell culture supernatants. J. Biosci. Bioeng. 2020 129(2):215-222. PubMed ID: 31473147 DOI: 10.1016/j.jbiosc.2019.08.003

11938 Hashida A, Uemura T, Kino-Oka M. Kinetics on aggregate behaviors of human induced pluripotent stem cells in static suspension and rotating flow cultures. J. Biosci. Bioeng. 2020 PubMed ID: 31826834 DOI: 10.1016/j.jbiosc.2019.11.005

12023 Nishimoto S, Mizuno T, Takahashi K, Nagano F, Yuzawa Y, Nishiyama A, Osafune K, Hitomi H, Nagamatsu T. CD140b and CD73 are markers for human induced pluripotent stem cell-derived erythropoietin-producing cells. FEBS Open Bio 2020 PubMed ID: 31977161 DOI: 10.1002/2211-5463.12800

12042 Ninomiya H, Intoh A, Ishimine H, Onuma Y, Ito Y, Michiue T, Tazaki A, Kato M. Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals. Chemosphere 2020 PubMed ID: 32092576 DOI: 10.1016/j.chemosphere.2020.126124

12075 Sasano Y, Fukumoto K, Tsukamoto Y, Akagi T, Akashi M. Construction of 3D cardiac tissue with synchronous powerful beating using human cardiomyocytes from human iPS cells prepared by a convenient differentiation method. J. Biosci. Bioeng. 2020 PubMed ID: 32151485 DOI: 10.1016/j.jbiosc.2020.01.001

12108 Tsukamoto Y, Akagi T, Akashi M. Vascularized cardiac tissue construction with orientation by layer-by-layer method and 3D printer. Sci Rep 2020 PubMed ID: 32218447 DOI: 10.1038/s41598-020-59371-y

13105 Takayama Y, Kushige H, Akagi Y, Suzuki Y, Kumagai Y, Kida YS. Selective Induction of Human Autonomic Neurons Enables Precise Control of Cardiomyocyte Beating. Sci Rep 2020 PubMed ID: 32528170 DOI: 10.1038/s41598-020-66303-3

13247 Shimbo E, Nukuzuma S, Tagawa YI. Human iPS cell-derived astrocytes support efficient replication of progressive multifocal leukoencephalopathy-type JC polyomavirus. Biochem Biophys Res Commun 2020 PubMed ID: 33008586 DOI: 10.1016/j.bbrc.2020.09.117

13619 Noninvasive optical coherence tomography imaging of three-dimensional cardiac tissues derived from human induced pluripotent stem cells Noninvasive optical coherence tomography imaging of three-dimensional cardiac tissues derived from human induced pluripotent stem cells J Tissue Eng Regen Med 2020 14(10):1384-1393 PubMed ID: 32593199 DOI: 10.1002/term.3092

13637 Ikeda M, Akagi T, Nagao M, Akashi M. Formulation Stability of Amphiphilic Poly(γ-Glutamic Acid) Nanoparticle and Evaluation of Cardiotoxicity of NPs With Human iPSC-Derived 3D-Cardiomyocyte Tissues J Pharm Sci 2020 109(10):2969-2974 PubMed ID: 32070703 DOI: 10.1016/j.xphs.2020.01.032

13641 Tsukamoto Y, Akagi T, Akashi M. Supersensitive Layer-by-Layer 3D Cardiac Tissues Fabricated on a Collagen Culture Vessel Using Human-Induced Pluripotent Stem Cells Tissue Eng Part C Methods 2020 26(9):493-502 PubMed ID: 32873187 DOI: 10.1089/ten.TEC.2020.0195

13854 Samura T, Miyagawa S, Kawamura T, Fukushima S, Yokoyama JY, Takeda M, Harada A, Ohashi F, Sato-Nishiuchi R, Toyofuku T, Toda K, Sekiguchi K, Sawa Y. Laminin-221 Enhances Therapeutic Effects of Human-Induced Pluripotent Stem Cell-Derived 3-Dimensional Engineered Cardiac Tissue Transplantation in a Rat Ischemic Cardiomyopathy Model J Am Heart Assoc 2020 9(16):e015841 PubMed ID: 32783519 DOI: 10.1161/JAHA.119.015841

11235 Yoda K, Ohnuki Y, Kurosawa H. Optimization of the treatment conditions with glycogen synthase kinase-3 inhibitor towards enhancing the proliferation of human induced pluripotent stem cells while maintaining an undifferentiated state under feeder-free conditions. J. Biosci. Bioeng. 2019 127(3):381-387 PubMed ID: 30292671 DOI: 10.1016/j.jbiosc.2018.09.002

11400 Konagaya S, Iwata H. Chemically defined conditions for long-term maintenance of pancreatic progenitors derived from human induced pluripotent stem cells. Sci Rep 2019 PubMed ID: 30679498 DOI: 10.1038/s41598-018-36606-7

11424 Dion J, Minoshima F, Saito S, Kiyoi K, Hasehira K, Tateno H. Photoactivable elimination of tumorigenic human induced pluripotent stem cells using a lectin-doxorubicin prodrug conjugate. Chembiochem 2019 PubMed ID: 30737871 DOI: 10.1002/cbic.201900086

11482 Matsumoto E, Koide N, Hanzawa H, Kiyama M, Ohta M, Kuwabara J, Takeda S, Takahashi M. Fabricating retinal pigment epithelial cell sheets derived from human induced pluripotent stem cells in an automated closed culture system for regenerative medicine. PLoS ONE 2019 PubMed ID: 30865653 DOI: 10.1371/journal.pone.0212369

4572 Kuroda T, Yasuda S, Tachi S, Matsuyama S, Kusakawa S, Tano K, Miura T, Matsuyama A, Sato Y. SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation. Nat Commun 2019 10(1):2175 PubMed ID: 31092818 DOI: 10.1038/s41467-019-09511-4

11600 Miura N, Ishihara Y, Miura Y, Kimoto M, Miura K. miR-520d-5p can reduce the mutations in hepatoma cancer cells and iPSCs-derivatives. BMC Cancer 2019 PubMed ID: 31202279 DOI: 10.1186/s12885-019-5786-y

11732 Chikae S, Kubota A, Nakamura H, Oda A, Yamanaka A, Akagi T, Akashi M. Three-dimensional bioprinting human cardiac tissue chips of using a painting needle method. Biotechnol. Bioeng. 2019 PubMed ID: 31369146 DOI: 10.1002/bit.27126

11735 Umemura Y, Maki I, Tsuchiya Y, Koike N, Yagita K. Human Circadian Molecular Oscillation Development Using Induced Pluripotent Stem Cells. J. Biol. Rhythms 2019 PubMed ID: 31368392 DOI: 10.1177/0748730419865436

11829 Sato M, Shiba N, Miyazaki D, Shiba Y, Echigoya Y, Yokota T, Takizawa H, Aoki Y, Takeda S, Nakamura A. Amelioration of intracellular Ca2+ regulation by exon-45 skipping in Duchenne muscular dystrophy-induced pluripotent stem cell-derived cardiomyocytes. Biochem. Biophys. Res. Commun. 2019 PubMed ID: 31585729 DOI: 10.1016/j.bbrc.2019.09.095

6890 Yamada S, Kanda Y. Retinoic acid promotes barrier functions in human iPSC-derived intestinal epithelial monolayers. J Pharmacol Sci 2019 140(4):337-344 PubMed ID: 31399314 DOI: 10.1016/j.jphs.2019.06.012

10388 Ken Tomochika, Nagisa Arimitsu, Masanori A. Murayama, Chieko Hirotsu, Kazufumi Nagata, Kenji Takai, Jun Shimizu, Tsutomu Akazawa, Yoshiaki Torii, Tasuku Umehara, Masahiro Iinuma, Hisateru Niki, Noboru Suzuki Transplantation of Human iPS Cell-Derived Neural Cells with an Artificial Nerve Conduit Leads to Cellular Retention in the Transplanted Area and Improves Motor Function in a Mouse Spinal Cord Injury Model Journal of St. Marianna University 2019 10:27-37 DOI: 10.17264/stmarieng.10.27

12314 Kanji Hori, Junichi Kuwabara, Yuji Tanaka, Mitsuhiro Nishida, Naoshi Koide, Masayo Takahashi A simple and static preservation system for shipping retinal pigment epithelium cell sheets J Tissue Eng Regen Med 2019 13(3):459-468 PubMed ID: 30644171 DOI: 10.1002/term.2805

12358 Ito E, Miyagawa S, Takeda M, Kawamura A, Harada A, Iseoka H, Yajima S, Sougawa N, Mochizuki-Oda N, Yasuda S, Sato Y, Sawa Y. Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application Sci Rep 2019 9(1):1881 PubMed ID: 30760836 DOI: 10.1038/s41598-018-38325-5

12369 Kamao H, Miki A, Kiryu J. Evaluation of Retinal Pigment Epithelial Cell Cytotoxicity of Recombinant Tissue Plasminogen Activat J Ophthalmol 2019 2019:7189241 PubMed ID: 31016039 DOI: 10.1155/2019/7189241

16886 Fujii S, Yoshida S, Inagaki E, Hatou S, Tsubota K, Takahashi M, Shimmura S, Sugita S. Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells Stem Cells Dev 2019 28(1):28-43 PubMed ID: 30251915 DOI: 10.1089/scd.2018.0058

10308 Iseoka H, Miyagawa S, Fukushima S, Saito A, Masuda S, Yajima S, Ito E, Sougawa N, Takeda M, Harada A, Lee JK, Sawa Y. Pivotal Role of Non-cardiomyocytes in Electromechanical and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissue. Tissue Eng Part A 2018 24:287-300 PubMed ID: 28498040 DOI: 10.1089/ten.TEA.2016.0535

10737 Kato Y, Kim MH, Kino-Oka M. Comparison of growth kinetics between static and dynamic cultures of human induced pluripotent stem cells. J. Biosci. Bioeng. 2018 125(6):736-740 PubMed ID: 29398548 DOI: 10.1016/j.jbiosc.2018.01.002

11171 Yamada S, Kubo Y, Yamazaki D, Sekino Y, Nomura Y, Yoshida S, Kanda Y. Tributyltin Inhibits Neural Induction of Human Induced Pluripotent Stem Cells. Sci Rep 2018 8(1):12155 PubMed ID: 30108368 DOI: 10.1038/s41598-018-30615-2

11234 Yasuda S, Kusakawa S, Kuroda T, Miura T, Tano K, Takada N, Matsuyama S, Matsuyama A, Nasu M, Umezawa A, Hayakawa T, Tsutsumi H, Sato Y. Tumorigenicity-associated characteristics of human iPS cell lines. PLoS ONE 2018 PubMed ID: 30286143 DOI: 10.1371/journal.pone.0205022

11325 Yamada S, Yamazaki D, Kanda Y. 5-Fluorouracil inhibits neural differentiation via Mfn1/2 reduction in human induced pluripotent stem cells. J Toxicol Sci 2018 PubMed ID: 30518710 DOI: 10.2131/jts.43.727

4069 Tadashi Kosawada, Email author Keita, Ohnishi, Hiroaki Satoh, Zhong-gang Feng, Kaoru Goto Novel methods to apply micro dynamic stimulations on cultured adhesive cells and its application in constructing gel-embedded three-dimensional neuronal structures differentiated from human iPS cells Microsystem Technologies 2018 24:625–638 DOI: 10.1007/s00542-017-3399-4

4113 Shoji M, Minato H, Ogaki S, Seki M, Suzuki Y, Kume S, Kuzuhara T. Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells. PLoS ONE 2018 PubMed ID: 30048506 DOI: 10.1371/journal.pone.0201239

4116 Uto S, Nishizawa S, Hikita A, Takato T, Hoshi K. Application of induced pluripotent stem cells for cartilage regeneration in CLAWN miniature pig osteochondral replacement model. Regen Ther 2018 PubMed ID: 30525076 DOI: 10.1016/j.reth.2018.06.003

4463 Masuda S, Matsuura K, Shimizu T. Preparation of iPS cell-derived CD31⁺ endothelial cells using three-dimensional suspension culture. Regen Ther 2018 9:1-9 PubMed ID: 30525069 DOI: 10.1016/j.reth.2018.06.004

4464 Takeda M, Miyagawa S, Fukushima S, Saito A, Ito E, Harada A, Matsuura R, Iseoka H, Sougawa N, Mochizuki-Oda N, Matsusaki M, Akashi M, Sawa Y. Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells. Tissue Eng Part C Methods 2018 24(1):56-67 PubMed ID: 28967302 DOI: 10.1089/ten.TEC.2017.0247

5773 Kim MH, Matsubara Y, Fujinaga Y, Kino-Oka M. A Simple and Robust Method for Culturing Human-Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Hemagglutinin. Biotechnol J 2018 13(2) PubMed ID: 29027750 DOI: 10.1002/biot.201700384

5777 Nakashima Y, Miyagi-Shiohira C, Noguchi H2, Omasa T. Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells. Mol Ther 2018 26(7):1715-1734 PubMed ID: 29929789 DOI: 10.1016/j.ymthe.2018.06.005

5799 Yasuda SY1, Ikeda T1,Shahsavarani H, Yoshida N, Nayer B, Hino M, Vartak-Sharma N, Suemori H, Hasegawa K. Chemically defined and growth-factor-free culture system for the expansion and derivation of human pluripotent stem cells. Nat Biomed Eng 2018 2(3):173-182 PubMed ID: 31015717 DOI: 10.1038/s41551-018-0200-7

5800 Sakai T et al Phenotypic Screening Using Patient-Derived Induced Pluripotent Stem Cells Identified Pyr3 as a Candidate Compound for the Treatment of Infantile Hypertrophic Cardiomyopathy. Int Heart J 2018 59(5):1096-1105 PubMed ID: 30101858 DOI: 10.1536/ihj.17-730

14053 Yamada S, Yamazaki D, Kanda Y. Silver nanoparticles inhibit neural induction in human induced pluripotent stem cells Nanotoxicology 2018 12(8):836-846 PubMed ID: 29902946 DOI: 10.1080/17435390.2018.1481238

7038 Liu L, Kamei KI, Yoshioka M, Nakajima M, Li J, Fujimoto N, Terada S, Tokunaga Y, Koyama Y, Sato H, Hasegawa K, Nakatsuji N, Chen Y. Nano-on-micro fibrous extracellular matrices for scalable expansion of human ES/iPS cells. Biomaterials 2017 124:47-54 PubMed ID: 28187394 DOI: 10.1016/j.biomaterials.2017.01.039

9814 Suga M, Tachikawa S, Tateyama D, Ohnuma K, Furue MK. Imaging-cytometry revealed spatial heterogeneities of marker expression in undifferentiated human pluripotent stem cells. In Vitro Cell. Dev. Biol. Anim. 2017 53:83-91 PubMed ID: 27573412 DOI: 10.1007/s11626-016-0084-3

10071 Kamao H, Mandai M, Ohashi W, Hirami Y, Kurimoto Y, Kiryu J, Takahashi M. Evaluation of the Surgical Device and Procedure for Extracellular Matrix-Scaffold-Supported Human iPSC-Derived Retinal Pigment Epithelium Cell Sheet Transplantation. Invest. Ophthalmol. Vis. Sci. 2017 58:211-220 PubMed ID: 28114582 DOI: 10.1167/iovs.16-19778

10426 Tateno H, Saito S. Engineering of a Potent Recombinant Lectin-Toxin Fusion Protein to Eliminate Human Pluripotent Stem Cells. Molecules 2017 22: PubMed ID: 28698527 DOI: 10.3390/molecules22071151

10503 Suzuki T, Shimizu Y, Furuhata E, Maeda S, Kishima M, Nishimura H, Enomoto S, Hayashizaki Y, Suzuki H. RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells. Blood Adv 2017 1:1699-1711 PubMed ID: 29296817 DOI: 10.1182/bloodadvances.2017005710

10933 Impairment of the transition from proliferative stage to prehypertrophic stage in chondrogenic differentiation of human induced pluripotent stem cells harboring the causative mutation of achondroplasia in fibroblast growth factor receptor 3 Regenerative Therapy 2017 6, 15-20 PubMed ID: 30271835 DOI: 10.1016/j.reth.2016.11.002

5765 Tateno H et al Development of a practical sandwich assay to detect human pluripotent stem cells using cell culture media. Regen Ther 2017 6:1-8 PubMed ID: 30271833 DOI: 10.1016/j.reth.2016.12.002

5766 Suzuki N, Arimitsu N, Shimizu J, Takai K, Hirotsu C, Ueda Y, Wakisaka S, Fujiwara N, Suzuki T. Neuronal Cell Sheets of Cortical Motor Neuron Phenotype Derived from Human iPSCs. Cell Transplant 2017 26(8):1355-1364 PubMed ID: 28901192 DOI: 10.1177/0963689717720280

5767 Ito M, Sun S, Fukuhara T, Suzuki R, Tamai M, Yamauchi T, Nakashima K, Tagawa Y, Okazaki S, Matsuura Y, Wakita T, Suzuki T. Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation. Oncotarget 2017 8(33):53899-53915 PubMed ID: 28903311 DOI: 10.18632/oncotarget.19108

5768 Alsayegh K, Matsuura K, Sekine H, Shimizu T. Dinaciclib potently suppresses MCL-1 and selectively induces the cell death in human iPS cells without affecting the viability of cardiac tissue. Sci Rep 2017 7:45577 PubMed ID: 28361959 DOI: 10.1038/srep45577

5774 Miyagoe-Suzuki Y, Nishiyama T, Nakamura M, Narita A, Takemura F, Masuda S, Minami N, Murayama K, Komaki H, Goto YI, Takeda S. Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status. Stem Cells Int 2017 2017:7906843 PubMed ID: 28491099 DOI: 10.1155/2017/7906843

5795 Shigeru Yamada Yusuke Kubo Daiju Yamazaki Yuko Sekino and Yasunari Kandaa Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells Sci Rep. 2017 7:40925. PubMed ID: 28112198 DOI: 10.1038/srep40925

5796 Komae H, Sekine H, Dobashi I, Matsuura K, Ono M, Okano T, Shimizu T. Three-dimensional functional human myocardial tissues fabricated from induced pluripotent stem cells. J Tissue Eng Regen Med 2017 11(3):926-935 PubMed ID: 25628251 DOI: 10.1002/term.1995

5797 Arauchi A, Matsuura K, Shimizu T, Okano T. Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture. Front Endocrinol (Lausanne) 2017 8:103 PubMed ID: 28588551 DOI: 10.3389/fendo.2017.00103

5798 Mihara Y, Matsuura K, Sakamoto Y, Okano T, Kokudo N, Shimizu T. Production of pancreatic progenitor cells from human induced pluripotent stem cells using a three-dimensional suspension bioreactor system. J Tissue Eng Regen Med 2017 11(11):3193-3201 PubMed ID: 28317340 DOI: 10.1002/term.2228

7047 Numaga-Tomita T, Kitajima N, Kuroda T, Nishimura A, Miyano K, Yasuda S, Kuwahara K, Sato Y, Ide T, Birnbaumer L, Sumimoto H, Mori Y, Nishida M. TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis. Sci Rep 2016 6:39383 PubMed ID: 27991560 DOI: 10.1038/srep39383

7080 Hayashi R, Ishikawa Y, Sasamoto Y, Katori R, Nomura N, Ichikawa T, Araki S, Soma T, Kawasaki S, Sekiguchi K, Quantock AJ, Tsujikawa M, Nishida K. Co-ordinated ocular development from human iPS cells and recovery of corneal function. Nature 2016 531:376-80 PubMed ID: 26958835 DOI: 10.1038/nature17000

7083 Matsuura K, Seta H, Haraguchi Y, Alsayegh K, Sekine H, Shimizu T, Hagiwara N, Yamazaki K, Okano T. TRPV-1-mediated elimination of residual iPS cells in bioengineered cardiac cell sheet tissues. Sci Rep 2016 6:21747 PubMed ID: 26888607 DOI: 10.1038/srep21747

9539 Amano Y, Nishiguchi A, Matsusaki M, Iseoka H, Miyagawa S, Sawa Y, Seo M, Yamaguchi T, Akashi M. Development of vascularized iPSC derived 3D-cardiomyocyte tissues by filtration Layer-by-Layer technique and their application for pharmaceutical assays. Acta Biomater 2016 33:110-21 PubMed ID: 26821339 DOI: 10.1016/j.actbio.2016.01.033

9674 Yamada S, Asanagi M, Hirata N, Itagaki H, Sekino Y, Kanda Y. Tributyltin induces mitochondrial fission through Mfn1 degradation in human induced pluripotent stem cells. Toxicol In Vitro 2016 34:257-63 PubMed ID: 27133438 DOI: 10.1016/j.tiv.2016.04.013

9838 Tomotsune D, Hirashima K, Fujii M, Yue F, Matsumoto K, Takizawa-Shirasawa S, Yokoyama T, Sasaki K. Enrichment of Pluripotent Stem Cell-Derived Hepatocyte-Like Cells by Ammonia Treatment. PLoS ONE 2016 11:e0162693 PubMed ID: 27632182 DOI: 10.1371/journal.pone.0162693

10891 Human iPS cell derived neural cell sheets exhibit mature neural and extendable scaffold functions and promote recovery in injured mouse spinal cords J Stem Cell Res Med 2016 1: 41-47 DOI: 10.15761/JSCRM.1000107

7271 Fujiwara N, Shimizu J, Takai K, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N. Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells. Exp. Neurol. 2015 271:423-31 PubMed ID: 26196079 DOI: 10.1016/j.expneurol.2015.07.008

7518 Kagawa Y, Matsuura K, Shimizu T, Tsuneda S. Direct measurement of local dissolved oxygen concentration spatial profiles in a cell culture environment. Biotechnol. Bioeng. 2015 112:1263-74 PubMed ID: 25565074 DOI: 10.1002/bit.25531

7542 M Iinuma, T Umehara, N Arimitsu, J Shimizu, H Misawa, K Takai, N Fujiwara, A Fujii, Y Ueda, S Wakisaka, T Suzuki, C Hirotsu, M Beppu, N Suzuki Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the trans-plantation to totally transected spinal cords in mice. Inflammation and Regeneration 2015 35:154-163 DOI: 10.2492/inflammregen.35.154

7562 Takuya Kuroda, Satoshi Yasuda, Satoko Matsuyama a, Keiko Tano, Shinji Kusakawa, Yoshiki Sawa, Shin Kawamata, Yoji Sato Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells. Regenerative Therapy 2015 2:17-23 PubMed ID: 31245455 DOI: 10.1016/j.reth.2015.08.001

5449 Tateno H, Onuma Y, Ito Y, Minoshima F, Saito S, Shimizu M, Aiki Y, Asashima M, Hirabayashi J. Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein. Stem Cell Reports 2015 4(5):811-20 PubMed ID: 25866158 DOI: 10.1016/j.stemcr.2015.02.016

5729 Matsuura K, Kodama F, Sugiyama K, Shimizu T, Hagiwara N, Okano T. Elimination of remaining undifferentiated induced pluripotent stem cells in the process of human cardiac cell sheet fabrication using a methionine-free culture condition. Tissue Eng Part C Methods 2015 21(3):330-8 PubMed ID: 25245976 DOI: 10.1089/ten.TEC.2014.0198

5752 Onuma Y, Higuchi K, Aiki Y, Shu Y, Asada M, Asashima M, Suzuki M, Imamura T, Ito Y. A stable chimeric fibroblast growth factor (FGF) can successfully replace basic FGF in human pluripotent stem cell culture. PLoS One 2015 10(4):e0118931 PubMed ID: 25850016 DOI: 10.1371/journal.pone.0118931

5753 Komatsu M, Konagaya S, Egawa EY, Iwata H. Maturation of human iPS cell-derived dopamine neuron precursors in alginate-Ca(2+) hydrogel. Biochim Biophys Acta 2015 1850(9):1669-75 PubMed ID: 25952075 DOI: 10.1016/j.bbagen.2015.04.011

5755 Konagaya S, Iwata H. Microencapsulation of dopamine neurons derived from human induced pluripotent stem cells. Biochim Biophys Acta 2015 1850(1):22-32 PubMed ID: 25281770 DOI: 10.1016/j.bbagen.2014.09.025

5757 Haraguchi Y, Matsuura K, Shimizu T, Yamato M, Okano T. Simple suspension culture system of human iPS cells maintaining their pluripotency for cardiac cell sheet engineering. J Tissue Eng Regen Med 2015 9(12):1363-75 PubMed ID: 23728860 DOI: 10.1002/term.1761

5788 Toriumi T, Takayama N, Murakami M, Sato M, Yuguchi M, Yamazaki Y, Eto K, Otsu M, Nakauchi H, Shirakawa T, Isokawa K, Honda MJ. Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth. Biomed Res 2015 36(1):31-45 PubMed ID: 25749149 DOI: 10.2220/biomedres.36.31

5789 Takaki Shiratsuchi, Hiroko Misawa, Asako Saito, Jun Shimizu, Masahiro Iinuma, Naruyoshi Fujiwara, Kenji Takai, Nagisa Arimitsu, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Moroe Beppu, Noboru Suzuki Sonic Hedgehog Supplementation Rapidly induces Myogenesis in Human Induced Pluripotent Stem Cells Journal of St. Marianna University 2015 6:225-233 DOI: 10.17264/stmarieng.6.225

5790 Konagaya S, Ando T, Yamauchi T, Suemori H, Iwata H. Long-term maintenance of human induced pluripotent stem cells by automated cell culture system. Sci Rep 2015 5:16647 PubMed ID: 26573336 DOI: 10.1038/srep16647

5792 Nagaoka M, Kobayashi M, Kawai C, Mallanna SK, Duncan SA. Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells. PLoS One 2015 10(8):e0136350 PubMed ID: 26308339 DOI: 10.1371/journal.pone.0136350

5793 Arai D, Hayakawa K, Ohgane J, Hirosawa M, Nakao Y, Tanaka S, Shiota K. An epigenetic regulatory element of the Nodal gene in the mouse and human genomes. Mech Dev 2015 136:143-54 PubMed ID: 25528267 DOI: 10.1016/j.mod.2014.12.003

5794 Mitsui K, Ide K, Takayama A, Wada T, Irie R, Kosai K. Conditionally replicating adenovirus prevents pluripotent stem cell-derived teratoma by specifically eliminating undifferentiated cells. Mol Ther Methods Clin Dev 2015 2:15026 PubMed ID: 26269798 DOI: 10.1038/mtm.2015.26

15253 Liu CY, Matsusaki M, Akashi M. Control of Cell-Cell Distance and Cell Densities in Millimeter-Sized 3D Tissues Constructed by Collagen Nanofiber Coating Techniques ACS Biomater Sci Eng 2015 1(8):639-645 PubMed ID: 33435087 DOI: 10.1021/acsbiomaterials.5b00015

5725 Imaizumi K, Nishishita N, Muramatsu M, Yamamoto T, Takenaka C, Kawamata S, Kobayashi K, Nishikawa S, Akuta T. A simple and highly effective method for slow-freezing human pluripotent stem cells using dimethyl sulfoxide, hydroxyethyl starch and ethylene glycol. PLoS One 2014 9(2):e88696 PubMed ID: 24533137 DOI: 10.1371/journal.pone.0088696

5732 Tokunaga K, Saitoh N, Goldberg IG, Sakamoto C, Yasuda Y, Yoshida Y, Yamanaka S, Nakao M. Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells. Sci Rep 2014 4:6996 PubMed ID: 25385348 DOI: 10.1038/srep06996

5733 Ohnuma K, Fujiki A, Yanagihara K, Tachikawa S, Hayashi Y, Ito Y, Onuma Y, Chan T, Michiue T, Furue MK, Asashima M Enzyme-free passage of human pluripotent stem cells by controlling divalent cations. Sci Rep 2014 4:4646 PubMed ID: 24721898 DOI: 10.1038/srep04646

5734 Tateno H, Onuma Y, Ito Y, Hiemori K, Aiki Y, Shimizu M, Higuchi K, Fukuda M, Warashina M, Honda S, Asashima M, Hirabayashi J. A medium hyperglycosylated podocalyxin enables noninvasive and quantitative detection of tumorigenic human pluripotent stem cells. Sci Rep 2014 4:4069 PubMed ID: 24518842 DOI: 10.1038/srep04069

5735 Yamada R, Hattori K, Tachikawa S, Tagaya M, Sasaki T, Sugiura S, Kanamori T, Ohnuma K. Control of adhesion of human induced pluripotent stem cells to plasma-patterned polydimethylsiloxane coated with vitronectin and γ-globulin. J Biosci Bioeng 2014 118(3):315-22 PubMed ID: 24656306 DOI: 10.1016/j.jbiosc.2014.02.009

5741 Tano K, Yasuda S, Kuroda T, Saito H, Umezawa A, Sato Y. A novel in vitro method for detecting undifferentiated human pluripotent stem cells as impurities in cell therapy products using a highly efficient culture system. PLoS One 2014 9(10):e110496 PubMed ID: 25347300 DOI: 10.1371/journal.pone.0110496

5745 Luo L, Kawakatsu M, Guo CW, Urata Y, Huang WJ, Ali H, Doi H, Kitajima Y, Tanaka T, Goto S, Ono Y, Xin HB, Hamano K, Li TS. Effects of antioxidants on the quality and genomic stability of induced pluripotent stem cells. Sci Rep 2014 4:3779 PubMed ID: 24445363 DOI: 10.1038/srep03779

5785 Kamao H, Mandai M, Okamoto S, Sakai N, Suga A, Sugita S, Kiryu J, Takahashi M Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application. Stem Cell Reports 2014 2(2):205-18 PubMed ID: 24527394 DOI: 10.1016/j.stemcr.2013.12.007

5786 Sekine K, Kagawa Y, Maeyama E, Ota H, Haraguchi Y, Matsuura K, Shimizu T. Oxygen consumption of human heart cells in monolayer culture. Biochem Biophys Res Commun 2014 452(3):834-9. PubMed ID: 25218502 DOI: 10.1016/j.bbrc.2014.09.018

5787 Kamao H, Mandai M, Wakamiya S, Ishida J, Goto K, Ono T, Suda T, Takahashi M, Kiryu J. Objective evaluation of the degree of pigmentation in human induced pluripotent stem cell-derived RPE. Invest Ophthalmol Vis Sci 2014 55(12):8309-18. PubMed ID: 25389202 DOI: 10.1167/iovs.14-14694

13757 Ishihara Y, Tsuno S, Kuwamoto S, Yamashita T, Endo Y, Hasegawa J, Miura N. Hsa-miR-520d converts fibroblasts into CD105+ populations Drugs R D 2014 14(4):253-64. PubMed ID: 25303886 DOI: 10.1007/s40268-014-0064-6

5710 Fujiwara N, Shimizu J, Takai K, Arimitsu N, Saito A, Kono T, Umehara T, Ueda Y, Wakisaka S, Suzuki T, Suzuki N. Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells. Neurosci Lett 2013 557 Pt B:129-34 PubMed ID: 24466594

5714 Onuma Y, Tateno H, Hirabayashi J, Ito Y, Asashima M. rBC2LCN, a new probe for live cell imaging of human pluripotent stem cells. Biochem Biophys Res Commun 2013 431(3):524-9 PubMed ID: 23321312 DOI: 10.1016/j.bbrc.2013.01.025

5722 Guo CW, Kawakatsu M, Idemitsu M, Urata Y, Goto S, Ono Y, Hamano K, Li TS. Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells. J Cell Physiol 2013 228(11):2159-66 PubMed ID: 23589166 DOI: 10.1002/jcp.24389

5783 Kanemura H, Go MJ, Nishishita N, Sakai N, Kamao H, Sato Y, Takahashi M, Kawamata S. Pigment epithelium-derived factor secreted from retinal pigment epithelium facilitates apoptotic cell death of iPSC. Sci Rep 2013 3:2334 PubMed ID: 23903667 DOI: 10.1038/srep02334

5784 Hiroyuki KAMAO, Junko ISHIDA, Taiji SUDA, Junichi KIRYU Generation of retinal pigment epithelium from human induced pluripotent stem cells showed polarized secretion of VEGF and PEDF Kawasaki Medical Journal 2013 39:155－162

7597 Teramura T, Takehara T, Onodera Y, Nakagawa K, Hamanishi C, Fukuda K. Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells. Biochem. Biophys. Res. Commun. 2012 417:836-41 PubMed ID: 22206673 DOI: 10.1016/j.bbrc.2011.12.052

5702 Hayashi R, Ishikawa Y, Ito M, Kageyama T, Takashiba K, Fujioka T, Tsujikawa M, Miyoshi H, Yamato M, Nakamura Y, Nishida K. Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium. PLoS One 2012 7(9):e45435 PubMed ID: 23029008 DOI: 10.1371/journal.pone.0045435

5706 Otsuji TG, Kurose Y, Suemori H, Tada M, Nakatsuji N. Dynamic link between histone H3 acetylation and an increase in the functional characteristics of human ESC/iPSC-derived cardiomyocytes. PLoS One 2012 7(9):e45010 PubMed ID: 22984602 DOI: 10.1371/journal.pone.0045010

5781 Matsuura K, Wada M, Shimizu T, Haraguchi Y, Sato F, Sugiyama K, Konishi K, Shiba Y, Ichikawa H, Tachibana A, Ikeda U, Yamato M, Hagiwara N, Okano T. Creation of human cardiac cell sheets using pluripotent stem cells. Biochem Biophys Res Commun 2012 425(2):321-7 PubMed ID: 22842572 DOI: 10.1016/j.bbrc.2012.07.089

5782 Ueda Y, Fujita S, Nishigaki T, Arima Y, Iwata H. Substrates for human pluripotent stem cell cultures in conditioned medium of mesenchymal stem cells. J Biomater Sci Polym Ed 2012 23(1-4):153-65 PubMed ID: 22133351 DOI: 10.1163/092050610X545797

7771 Ogawa S, Tokumoto Y, Miyake J, Nagamune T. Induction of oligodendrocyte differentiation from adult human fibroblast-derived induced pluripotent stem cells. In Vitro Cell. Dev. Biol. Anim. 2011 47:464-9 PubMed ID: 21695581 DOI: 10.1007/s11626-011-9435-2

5750 Kumazaki T, Kurata S, Matsuo T, Mitsui Y, Takahashi T. Establishment of human induced pluripotent stem cell lines from normal fibroblast TIG-1. Hum Cell 2011 24(2):96-103 PubMed ID: 21562774 DOI: 10.1007/s13577-011-0016-1

5780 Nishigaki T, Teramura Y, Nasu A, Takada K, Toguchida J, Iwata H. Highly efficient cryopreservation of human induced pluripotent stem cells using a dimethyl sulfoxide-free solution. Int J Dev Biol 2011 55(3):305-11 PubMed ID: 21710436 DOI: 10.1387/ijdb.103145tn

5779 Takenaka C, Nishishita N, Takada N, Jakt LM, Kawamata S. Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53. Exp Hematol 2010 38(2):154-62 PubMed ID: 19922768 DOI: 10.1016/j.exphem.2009.11.003

10089 Burden ML, Burden AC. The American Diabetes Association screening questionnaire for diabetes. Is it worthwhile in the U.K.? Diabetes Care 1994 17:97 PubMed ID: 8112198 DOI: 10.2337/diacare.17.1.97